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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0004
log Bayes Factor = 32.8452
contains 2 variants:
rs6658988
lBF = 17.834
Chr 1 : 4,987,953
rs79655101
lBF = 9.704
Chr 4 : 53,338,793
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
F30-F39 Mood [affective] disorders
1.000 0.000 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
N40-N51 Diseases of male genital organs
1.000 0.000 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
N20-N23 Urolithiasis
0.999 0.001 0.000
F31 Bipolar affective disorder
0.999 0.001 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.999 0.001 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z51 Other medical care
0.999 0.001 0.000
Z46 Fitting and adjustment of other devices
0.998 0.002 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
N20 Calculus of kidney and ureter
0.997 0.003 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
Y95 Nosocomial condition
0.997 0.003 0.000
E11 Non-insulin-dependent diabetes mellitus
0.996 0.004 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.996 0.004 0.000
Z51.1 Chemotherapy session for neoplasm
0.996 0.004 0.000
Chapter II Neoplasms
0.994 0.006 0.000
E11.4 With neurological complications
0.994 0.006 0.000
C60-C63 Malignant neoplasms of male genital organs
0.993 0.007 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.993 0.007 0.000
Z50 Care involving use of rehabilitation procedures
0.992 0.008 0.000
C61 Malignant neoplasm of prostate
0.992 0.008 0.000
M48 Other spondylopathies
0.992 0.008 0.000
Z46.6 Fitting and adjustment of urinary device
0.990 0.010 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.989 0.011 0.000
N30-N39 Other diseases of urinary system
0.989 0.011 0.000
N48 Other disorders of penis
0.988 0.012 0.000
M48.0 Spinal stenosis
0.984 0.016 0.000
M48.06 Spinal stenosis (Lumbar region)
0.983 0.017 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.982 0.018 0.000
N35 Urethral stricture
0.981 0.019 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.979 0.021 0.000
F31.9 Bipolar affective disorder, unspecified
0.978 0.022 0.000
N20.2 Calculus of kidney with calculus of ureter
0.978 0.022 0.000
N35.9 Urethral stricture, unspecified
0.977 0.023 0.000
N40 Hyperplasia of prostate
0.975 0.025 0.000
G62 Other polyneuropathies
0.974 0.026 0.000
M80-M85 Disorders of bone density and structure
0.974 0.026 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.973 0.027 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.969 0.031 0.000
N41 Inflammatory diseases of prostate
0.968 0.032 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.967 0.033 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.966 0.034 0.000
N32 Other disorders of bladder
0.961 0.039 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.960 0.040 0.000
Z50.2 Alcohol rehabilitation
0.958 0.042 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.957 0.043 0.000
M65-M68 Disorders of synovium and tendon
0.957 0.043 0.000
N00-N08 Glomerular diseases
0.955 0.045 0.000
Y40 Systemic antibiotics
0.955 0.045 0.000
M46 Other inflammatory spondylopathies
0.954 0.046 0.000
Chapter I Certain infectious and parasitic diseases
0.952 0.048 0.000
E87.0 Hyperosmolality and hypernatraemia
0.946 0.054 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.942 0.058 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.941 0.059 0.000
E11.2 With renal complications
0.939 0.061 0.000
G82 Paraplegia and tetraplegia
0.934 0.066 0.000
N48.8 Other specified disorders of penis
0.933 0.067 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.930 0.070 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.927 0.073 0.000
G40-G47 Episodic and paroxysmal disorders
0.927 0.073 0.000
N21 Calculus of lower urinary tract
0.926 0.074 0.000
G81 Hemiplegia
0.926 0.074 0.000
N32.1 Vesicointestinal fistula
0.924 0.076 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.924 0.076 0.000
F10.2 Dependence syndrome
0.923 0.077 0.000
N32.0 Bladder-neck obstruction
0.920 0.080 0.000
M91-M94 Chondropathies
0.919 0.081 0.000
A30-A49 Other bacterial diseases
0.916 0.084 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.914 0.086 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.914 0.086 0.000
N48.0 Leukoplakia of penis
0.913 0.087 0.000
N20.1 Calculus of ureter
0.913 0.087 0.000
E87.5 Hyperkalaemia
0.913 0.087 0.000
M85 Other disorders of bone density and structure
0.910 0.090 0.000
Y43 Primarily systemic agents
0.910 0.090 0.000
G62.9 Polyneuropathy, unspecified
0.910 0.090 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.907 0.092 0.000
M40-M43 Deforming dorsopathies
0.907 0.093 0.000
Z51.3 Blood transfusion without reported diagnosis
0.905 0.095 0.000
G63.2 Diabetic polyneuropathy
0.902 0.098 0.000
G47 Sleep disorders
0.899 0.101 0.000
F10.1 Harmful use
0.898 0.102 0.000
M65 Synovitis and tenosynovitis
0.897 0.103 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.897 0.103 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.897 0.103 0.000
B95-B98 Bacterial, viral and other infectious agents
0.896 0.104 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.890 0.110 0.000
M60-M63 Disorders of muscles
0.887 0.113 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.886 0.114 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.884 0.116 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.883 0.117 0.000
C34 Malignant neoplasm of bronchus and lung
0.883 0.117 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.881 0.119 0.000
N48.1 Balanoposthitis
0.879 0.121 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.879 0.121 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.878 0.122 0.000
G81.9 Hemiplegia, unspecified
0.878 0.122 0.000
M84 Disorders of continuity of bone
0.876 0.124 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.876 0.124 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.872 0.128 0.000
Z46.8 Fitting and adjustment of other specified devices
0.869 0.131 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.868 0.132 0.000
G47.3 Sleep apnoea
0.867 0.133 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.867 0.133 0.000
N21.0 Calculus in bladder
0.867 0.133 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.866 0.134 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.864 0.136 0.000
G62.8 Other specified polyneuropathies
0.864 0.136 0.000
G82.2 Paraplegia, unspecified
0.864 0.136 0.000
Z43 Attention to artificial openings
0.864 0.136 0.000
M80 Osteoporosis with pathological fracture
0.860 0.140 0.000
A40 Streptococcal septicaemia
0.859 0.141 0.000
F30 Manic episode
0.859 0.141 0.000
N20.0 Calculus of kidney
0.858 0.142 0.000
W20-W49 Exposure to inanimate mechanical forces
0.858 0.142 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.856 0.144 0.000
G54 Nerve root and plexus disorders
0.855 0.145 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.855 0.145 0.000
C34.9 Bronchus or lung, unspecified
0.855 0.145 0.000
G44 Other headache syndromes
0.853 0.147 0.000
E87.3 Alkalosis
0.852 0.148 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.852 0.148 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.852 0.148 0.000
Z52 Donors of organs and tissues
0.851 0.149 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.848 0.152 0.000
M41 Scoliosis
0.848 0.152 0.000
X60-X84 Intentional self-harm
0.846 0.154 0.000
N48.6 Balanitis xerotica obliterans
0.842 0.158 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.840 0.160 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.839 0.161 0.000
E11.3 With ophthalmic complications
0.837 0.163 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.836 0.164 0.000
Y48 Anaesthetics and therapeutic gases
0.835 0.165 0.000
F10.0 Acute intoxication
0.835 0.165 0.000
V80-V89 Other land transport accidents
0.834 0.165 0.000
F33 Recurrent depressive disorder
0.832 0.168 0.000
G80 Infantile cerebral palsy
0.831 0.169 0.000
N20.9 Urinary calculus, unspecified
0.830 0.170 0.000
N46 Male infertility
0.829 0.171 0.000
Y57 Other and unspecified drugs and medicaments
0.828 0.172 0.000
G61 Inflammatory polyneuropathy
0.826 0.174 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.826 0.174 0.000
E74 Other disorders of carbohydrate metabolism
0.826 0.174 0.000
F10.4 Withdrawal state with delirium
0.824 0.176 0.000
N75 Diseases of Bartholin's gland
0.824 0.176 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.822 0.178 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.820 0.180 0.000
E87.7 Fluid overload
0.819 0.181 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.818 0.182 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.816 0.184 0.000
N23 Unspecified renal colic
0.816 0.184 0.000
N73 Other female pelvic inflammatory diseases
0.816 0.184 0.000
G58 Other mononeuropathies
0.814 0.186 0.000
Z40 Prophylactic surgery
0.813 0.187 0.000
G59.0 Diabetic mononeuropathy
0.811 0.189 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.811 0.189 0.000
C62 Malignant neoplasm of testis
0.811 0.189 0.000
M66 Spontaneous rupture of synovium and tendon
0.810 0.190 0.000
N75.0 Cyst of Bartholin's gland
0.810 0.190 0.000
M94 Other disorders of cartilage
0.809 0.191 0.000
Y43.3 Other antineoplastic drugs
0.807 0.193 0.000
M41.9 Scoliosis, unspecified
0.805 0.195 0.000
B15-B19 Viral hepatitis
0.805 0.195 0.000
G83 Other paralytic syndromes
0.803 0.197 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.803 0.197 0.000
M45 Ankylosing spondylitis
0.802 0.198 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.801 0.199 0.000
Y40.3 Macrolides
0.800 0.200 0.000
Z51.6 Desensitisation to allergens
0.799 0.201 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.798 0.202 0.000
Y40.8 Other systemic antibiotics
0.797 0.203 0.000
E13 Other specified diabetes mellitus
0.797 0.203 0.000
G35 Multiple sclerosis
0.797 0.203 0.000
Y40.0 Penicillins
0.796 0.203 0.000
A40.8 Other streptococcal septicaemia
0.795 0.205 0.000
N34 Urethritis and urethral syndrome
0.795 0.205 0.000
M85.8 Other specified disorders of bone density and structure
0.794 0.206 0.000
F32 Depressive episode
0.793 0.207 0.000
G20-G26 Extrapyramidal and movement disorders
0.793 0.207 0.000
Z57 Occupational exposure to risk-factors
0.791 0.209 0.000
N48.5 Ulcer of penis
0.791 0.209 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.791 0.209 0.000
A46 Erysipelas
0.790 0.210 0.000
Z29 Need for other prophylactic measures
0.789 0.211 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.789 0.211 0.000
M00-M03 Infectious arthropathies
0.788 0.212 0.000
G62.1 Alcoholic polyneuropathy
0.787 0.212 0.000
N17-N19 Renal failure
0.787 0.213 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.787 0.213 0.000
E11.8 With unspecified complications
0.786 0.214 0.000
C15-C26 Malignant neoplasms of digestive organs
0.785 0.215 0.000
G54.0 Brachial plexus disorders
0.785 0.215 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.784 0.216 0.000
D80-D89 Certain disorders involving the immune mechanism
0.784 0.216 0.000
Z63 Other problems related to primary support group, including family circumstances
0.782 0.218 0.000
Y43.1 Antineoplastic antimetabolites
0.781 0.219 0.000
Z53.9 Procedure not carried out, unspecified reason
0.779 0.221 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.778 0.222 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.777 0.223 0.000
G47.8 Other sleep disorders
0.776 0.224 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.775 0.225 0.000
Z41 Procedures for purposes other than remedying health state
0.774 0.226 0.000
M85.0 Fibrous dysplasia (monostotic)
0.773 0.227 0.000
Chapter VII Diseases of the eye and adnexa
0.773 0.227 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.772 0.228 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.771 0.229 0.000
W00-W19 Falls
0.770 0.230 0.000
G44.2 Tension-type headache
0.767 0.233 0.000
F80-F89 Disorders of psychological development
0.766 0.234 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.766 0.234 0.000
Z49 Care involving dialysis
0.765 0.235 0.000
E73 Lactose intolerance
0.764 0.236 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.764 0.236 0.000
G70-G73 Diseases of myoneural junction and muscle
0.764 0.236 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.764 0.236 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.762 0.238 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.762 0.238 0.000
E11.1 With ketoacidosis
0.760 0.240 0.000
F34 Persistent mood [affective] disorders
0.759 0.241 0.000
V01-V09 Pedestrian injured in transport accident
0.758 0.242 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.757 0.243 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.757 0.243 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.754 0.245 0.000
W50-W64 Exposure to animate mechanical forces
0.754 0.245 0.000
C71 Malignant neoplasm of brain
0.754 0.246 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.753 0.247 0.000
G82.5 Tetraplegia, unspecified
0.753 0.247 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.753 0.247 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.753 0.247 0.000
M84.0 Malunion of fracture
0.751 0.249 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.750 0.250 0.000
F03 Unspecified dementia
0.750 0.250 0.000
H25-H28 Disorders of lens
0.748 0.252 0.000
M93 Other osteochondropathies
0.746 0.254 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.746 0.254 0.000
M62 Other disorders of muscle
0.745 0.254 0.000
E11.6 With other specified complications
0.745 0.255 0.000
N73.6 Female pelvic peritoneal adhesions
0.745 0.255 0.000
M60 Myositis
0.744 0.256 0.000
N05 Unspecified nephritic syndrome
0.744 0.256 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.742 0.258 0.000
G25 Other extrapyramidal and movement disorders
0.742 0.258 0.000
M94.8 Other specified disorders of cartilage
0.741 0.258 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.741 0.259 0.000
M46.4 Discitis, unspecified
0.740 0.260 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.740 0.260 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.740 0.260 0.000
H26 Other cataract
0.738 0.262 0.000
N17 Acute renal failure
0.736 0.264 0.000
C60 Malignant neoplasm of penis
0.733 0.267 0.000
N32.9 Bladder disorder, unspecified
0.733 0.267 0.000
F01 Vascular dementia
0.733 0.267 0.000
C25 Malignant neoplasm of pancreas
0.732 0.268 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.732 0.268 0.000
Z52.4 Kidney donor
0.731 0.269 0.000
F30.0 Hypomania
0.728 0.272 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.728 0.272 0.000
E11.0 With coma
0.728 0.272 0.000
Z43.5 Attention to cyctostomy
0.727 0.273 0.000
G62.0 Drug-induced polyneuropathy
0.726 0.274 0.000
Y52 Agents primarily affecting the cardiovascular system
0.724 0.276 0.000
A65-A69 Other spirochaetal diseases
0.724 0.276 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.721 0.279 0.000
M85.6 Other cyst of bone
0.721 0.279 0.000
N03 Chronic nephritic syndrome
0.720 0.280 0.000
D86 Sarcoidosis
0.720 0.280 0.000
G30-G32 Other degenerative diseases of the nervous system
0.720 0.280 0.000
A41 Other septicaemia
0.719 0.281 0.000
F10.3 Withdrawal state
0.719 0.281 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.719 0.281 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.718 0.282 0.000
W25 Contact with sharp glass
0.718 0.282 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
F38 Other mood [affective] disorders
0.717 0.283 0.000
E87.4 Mixed disorder of acid-base balance
0.717 0.283 0.000
N44 Torsion of testis
0.717 0.283 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.717 0.283 0.000
G52 Disorders of other cranial nerves
0.717 0.283 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.717 0.283 0.000
F31.7 Bipolar affective disorder, currently in remission
0.716 0.284 0.000
F31.8 Other bipolar affective disorders
0.716 0.284 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.716 0.284 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.716 0.284 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
Y58 Bacterial vaccines
0.716 0.284 0.000
Y59 Other and unspecified vaccines and biological substances
0.716 0.284 0.000
Y40.9 Systemic antibiotic, unspecified
0.716 0.284 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.716 0.284 0.000
Z46.1 Fitting and adjustment of hearing aid
0.716 0.284 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.716 0.284 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.716 0.284 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.716 0.284 0.000
Y96 Work-related condition
0.715 0.284 0.000
Y97 Environmental-pollution-related condition
0.715 0.284 0.000
Y98 Lifestyle-related condition
0.715 0.284 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.715 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
H26.4 After-cataract
0.715 0.285 0.000
Z44 Fitting and adjustment of external prosthetic device
0.715 0.285 0.000
G80.9 Infantile cerebral palsy, unspecified
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.714 0.285 0.000
W18 Other fall on same level
0.714 0.286 0.000
E11.7 With multiple complications
0.714 0.286 0.000
G64 Other disorders of peripheral nervous system
0.714 0.286 0.000
M49 Spondylopathies in diseases classified elsewhere
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
M92 Other juvenile osteochondrosis
0.712 0.288 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.712 0.288 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.712 0.288 0.000
Z50.3 Drug rehabilitation
0.711 0.289 0.000
Z50.6 Orthoptic training
0.711 0.289 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.711 0.289 0.000
M48.2 Kissing spine
0.711 0.289 0.000
M48.3 Traumatic spondylopathy
0.711 0.289 0.000
M48.4 Fatigue fracture of vertebra
0.711 0.289 0.000
M48.8 Other specified spondylopathies
0.711 0.289 0.000
M48.9 Spondylopathy, unspecified
0.711 0.289 0.000
N33 Bladder disorders in diseases classified elsewhere
0.709 0.291 0.000
N37 Urethral disorders in diseases classified elsewhere
0.709 0.291 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.708 0.291 0.000
N48.3 Priapism
0.708 0.292 0.000
A40.9 Streptococcal septicaemia, unspecified
0.708 0.292 0.000
Z51.9 Medical care, unspecified
0.708 0.292 0.000
M66.4 Spontaneous rupture of other tendons
0.708 0.292 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.708 0.292 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.708 0.292 0.000
Z54 Convalescence
0.707 0.293 0.000
G82.1 Spastic paraplegia
0.706 0.294 0.000
Z29.1 Prophylactic immunotherapy
0.706 0.294 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.705 0.294 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.705 0.295 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.705 0.295 0.000
M48.04 Spinal stenosis (Thoracic region)
0.705 0.295 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.705 0.295 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.705 0.295 0.000
N36 Other disorders of urethra
0.705 0.295 0.000
N04 Nephrotic syndrome
0.705 0.295 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.705 0.295 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.705 0.295 0.000
F10.5 Psychotic disorder
0.704 0.295 0.000
M40 Kyphosis and lordosis
0.704 0.296 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.704 0.296 0.000
N35.0 Posttraumatic urethral stricture
0.703 0.296 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.703 0.296 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.703 0.297 0.000
G60 Hereditary and idiopathic neuropathy
0.702 0.298 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.702 0.298 0.000
F11 Mental and behavioural disorders due to use of opioids
0.702 0.298 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.702 0.298 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.702 0.298 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.702 0.298 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.702 0.298 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.702 0.298 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.702 0.298 0.000
M67 Other disorders of synovium and tendon
0.701 0.298 0.000
G44.0 Cluster headache syndrome
0.701 0.299 0.000
V20-V29 Motorcycle rider injured in transport accident
0.701 0.299 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.700 0.299 0.000
Z51.8 Other specified medical care
0.700 0.300 0.000
F02 Dementia in other diseases classified elsewhere
0.700 0.300 0.000
C10 Malignant neoplasm of oropharynx
0.700 0.300 0.000
Z56 Problems related to employment and unemployment
0.699 0.301 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.699 0.301 0.000
G62.2 Polyneuropathy due to other toxic agents
0.699 0.301 0.000
M83 Adult osteomalacia
0.698 0.302 0.000
F10.6 Amnesic syndrome
0.698 0.302 0.000
F10.7 Residual and late-onset psychotic disorder
0.698 0.302 0.000
F10.8 Other mental and behavioural disorders
0.698 0.302 0.000
N21.1 Calculus in urethra
0.697 0.303 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.697 0.303 0.000
M65.8 Other synovitis and tenosynovitis
0.696 0.304 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.696 0.304 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.696 0.304 0.000
X78 Intentional self-harm by sharp object
0.696 0.304 0.000
M05-M14 Inflammatory polyarthropathies
0.696 0.304 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.304 0.000
G43 Migraine
0.695 0.305 0.000
C09 Malignant neoplasm of tonsil
0.695 0.305 0.000
D80 Immunodeficiency with predominantly antibody defects
0.695 0.305 0.000
Y45.2 Propionic acid derivatives
0.694 0.306 0.000
N41.2 Abscess of prostate
0.694 0.306 0.000
N41.3 Prostatocystitis
0.694 0.306 0.000
N41.8 Other inflammatory diseases of prostate
0.694 0.306 0.000
D38.1 Trachea, bronchus and lung
0.694 0.306 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.693 0.306 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.693 0.307 0.000
Z52.0 Blood donor
0.692 0.308 0.000
Y45.8 Other analgesics and antipyretics
0.692 0.308 0.000
F39 Unspecified mood [affective] disorder
0.691 0.308 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.690 0.310 0.000
N17.9 Acute renal failure, unspecified
0.690 0.310 0.000
N32.2 Vesical fistula, not elsewhere classified
0.689 0.311 0.000
N32.4 Rupture of bladder, nontraumatic
0.689 0.311 0.000
G61.0 Guillain-Barre syndrome
0.689 0.311 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.689 0.311 0.000
E88 Other metabolic disorders
0.687 0.312 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.687 0.313 0.000
F33.9 Recurrent depressive disorder, unspecified
0.687 0.313 0.000
M82 Osteoporosis in diseases classified elsewhere
0.687 0.313 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.686 0.314 0.000
E20-E35 Disorders of other endocrine glands
0.686 0.314 0.000
B50-B64 Protozoal diseases
0.685 0.315 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.685 0.315 0.000
Z43.2 Attention to ileostomy
0.685 0.315 0.000
N00 Acute nephritic syndrome
0.685 0.315 0.000
N01 Rapidly progressive nephritic syndrome
0.685 0.315 0.000
N06 Isolated proteinuria with specified morphological lesion
0.685 0.315 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.685 0.315 0.000
Y40.2 Chloramphenicol group
0.684 0.315 0.000
Y40.4 Tetracyclines
0.684 0.315 0.000
Y40.5 Aminoglycosides
0.684 0.315 0.000
Y40.6 Rifamycins
0.684 0.315 0.000
Y40.7 Antifungal antibiotics, systemically used
0.684 0.315 0.000
M46.0 Spinal enthesopathy
0.684 0.316 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.684 0.316 0.000
M46.2 Osteomyelitis of vertebra
0.684 0.316 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.684 0.316 0.000
M46.5 Other infective spondylopathies
0.684 0.316 0.000
M46.8 Other specified inflammatory spondylopathies
0.684 0.316 0.000
F06.7 Mild cognitive disorder
0.684 0.316 0.000
C15 Malignant neoplasm of oesophagus
0.684 0.316 0.000
Y00-Y09 Assault
0.683 0.316 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.683 0.316 0.000
A15-A19 Tuberculosis
0.682 0.318 0.000
A20-A28 Certain zoonotic bacterial diseases
0.682 0.318 0.000
A70-A74 Other diseases caused by chlamydiae
0.682 0.318 0.000
A75-A79 Rickettsioses
0.682 0.318 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.682 0.318 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.682 0.318 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.682 0.318 0.000
Z43.1 Attention to gastrostomy
0.681 0.319 0.000
C62.9 Testis, unspecified
0.680 0.320 0.000
E65-E68 Obesity and other hyperalimentation
0.680 0.320 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.679 0.321 0.000
Y48.2 Other and unspecified general anaesthetics
0.677 0.323 0.000
C71.9 Brain, unspecified
0.676 0.324 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.676 0.324 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.676 0.324 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.675 0.325 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.675 0.325 0.000
G63.1 Polyneuropathy in neoplastic disease
0.675 0.325 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.675 0.325 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.675 0.325 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.675 0.325 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.675 0.325 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.675 0.325 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.675 0.325 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.674 0.326 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.673 0.327 0.000
F30.9 Manic episode, unspecified
0.672 0.328 0.000
E85 Amyloidosis
0.672 0.328 0.000
C34.3 Lower lobe, bronchus or lung
0.672 0.328 0.000
Chapter X Diseases of the respiratory system
0.671 0.329 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.671 0.329 0.000
G41 Status epilepticus
0.671 0.329 0.000
B65-B83 Helminthiases
0.671 0.329 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.670 0.330 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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