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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-28396994
log Bayes Factor = 52.6925
Chromosome 6   position 29,114,616  (GRCh37) Explore Affx-28396994 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.009 0.991
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.038 0.962
E10.2 With renal complications
0.000 0.044 0.956
E10.1 With ketoacidosis
0.000 0.122 0.878
E10.4 With neurological complications
0.000 0.132 0.868
E05.8 Other thyrotoxicosis
0.000 0.196 0.804
E16.1 Other hypoglycaemia
0.000 0.204 0.796
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.214 0.786
E13 Other specified diabetes mellitus
0.000 0.227 0.773
E40-E46 Malnutrition
0.000 0.236 0.764
E10.7 With multiple complications
0.000 0.245 0.754
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E10.0 With coma
0.000 0.288 0.712
E10.6 With other specified complications
0.000 0.311 0.689
E14 Unspecified diabetes mellitus
0.000 0.312 0.688
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.357 0.642
E10.5 With peripheral circulatory complications
0.000 0.358 0.642
E07 Other disorders of thyroid
0.000 0.376 0.624
E03 Other hypothyroidism
0.000 0.378 0.622
E13.9 Without complications
0.000 0.379 0.621
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.615 0.385 0.000
E06 Thyroiditis
0.000 0.401 0.599
E14.3 With ophthalmic complications
0.000 0.403 0.597
E46 Unspecified protein-energy malnutrition
0.000 0.405 0.595
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.412 0.588
E13.8 With unspecified complications
0.000 0.446 0.554
E13.7 With multiple complications
0.000 0.446 0.554
E13.6 With other specified complications
0.000 0.446 0.554
E13.5 With peripheral circulatory complications
0.000 0.446 0.554
E13.4 With neurological complications
0.000 0.446 0.554
E13.2 With renal complications
0.000 0.446 0.554
E13.1 With ketoacidosis
0.000 0.446 0.554
E13.0 With coma
0.000 0.446 0.554
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.452 0.547
E45 Retarded development following protein-energy malnutrition
0.000 0.452 0.547
E43 Unspecified severe protein-energy malnutrition
0.000 0.452 0.547
E42 Marasmic kwashiorkor
0.000 0.452 0.547
E41 Nutritional marasmus
0.000 0.452 0.547
E40 Kwashiorkor
0.000 0.452 0.547
E14.1 With ketoacidosis
0.000 0.455 0.545
E13.3 With ophthalmic complications
0.000 0.459 0.541
E10.8 With unspecified complications
0.000 0.470 0.530
E14.8 With unspecified complications
0.000 0.474 0.526
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E14.6 With other specified complications
0.000 0.489 0.511
E14.4 With neurological complications
0.000 0.497 0.502
E06.9 Thyroiditis, unspecified
0.000 0.502 0.498
E07.8 Other specified disorders of thyroid
0.000 0.506 0.494
E14.7 With multiple complications
0.000 0.506 0.493
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.517 0.483
E14.5 With peripheral circulatory complications
0.000 0.527 0.473
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.531 0.469
E14.0 With coma
0.000 0.535 0.465
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.541 0.459
E14.2 Withrenal complications
0.000 0.543 0.456
E07.1 Dyshormogenetic goitre
0.000 0.553 0.447
E07.0 Hypersecretion of calcitonin
0.000 0.553 0.447
E03.5 Myxoedema coma
0.000 0.554 0.446
E03.4 Atrophy of thyroid (acquired)
0.000 0.554 0.446
E03.3 Postinfectious hypothyroidism
0.000 0.554 0.446
K90 Intestinal malabsorption
0.000 0.562 0.438
E06.1 Subacute thyroiditis
0.000 0.564 0.436
E03.1 Congenital hypothyroidism without goitre
0.000 0.566 0.434
E06.4 Drug-induced thyroiditis
0.000 0.571 0.429
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.571 0.429
E06.0 Acute thyroiditis
0.000 0.571 0.429
E06.5 Other chronic thyroiditis
0.000 0.584 0.416
E44.1 Mild protein-energy malnutrition
0.000 0.607 0.393
E44.0 Moderate protein-energy malnutrition
0.000 0.607 0.393
E03.9 Hypothyroidism, unspecified
0.000 0.611 0.389
E03.8 Other specified hypothyroidism
0.000 0.613 0.387
E65-E68 Obesity and other hyperalimentation
0.000 0.621 0.379
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.640 0.360
E50-E64 Other nutritional deficiencies
0.000 0.668 0.332
K90.3 Pancreatic steatorrhoea
0.000 0.686 0.314
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.686 0.314
K90.1 Tropical sprue
0.000 0.686 0.314
K90.8 Other intestinal malabsorption
0.000 0.693 0.307
E20-E35 Disorders of other endocrine glands
0.000 0.727 0.273
R31 Unspecified haematuria
0.272 0.728 0.000
E67 Other hyperalimentation
0.000 0.728 0.272
E68 Sequelae of hyperalimentation
0.000 0.728 0.272
E07.9 Disorder of thyroid, unspecified
0.000 0.740 0.260
K90.9 Intestinal malabsorption, unspecified
0.000 0.743 0.257
E24 Cushing's syndrome
0.000 0.747 0.253
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.750 0.250
E65 Localised adiposity
0.000 0.756 0.243
E21.3 Hyperparathyroidism, unspecified
0.000 0.761 0.239
E51 Thiamine deficiency
0.000 0.762 0.238
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.762 0.238
E50 Vitamin A deficiency
0.000 0.762 0.238
E60 Dietary zinc deficiency
0.000 0.762 0.238
E59 Dietary selenium deficiency
0.000 0.762 0.238
E52 Niacin deficiency [pellagra]
0.000 0.762 0.238
E54 Ascorbic acid deficiency
0.000 0.766 0.233
E56 Other vitamin deficiencies
0.000 0.774 0.226
E58 Dietary calcium deficiency
0.000 0.781 0.219
E24.9 Cushing's syndrome, unspecified
0.000 0.781 0.219
E63 Other nutritional deficiencies
0.000 0.784 0.216
E24.0 Pituitary-dependent Cushing's disease
0.000 0.788 0.212
E55 Vitamin D deficiency
0.000 0.793 0.207
E61 Deficiency of other nutrient elements
0.000 0.793 0.207
E24.2 Drug-induced Cushing's syndrome
0.000 0.800 0.200
E20 Hypoparathyroidism
0.000 0.802 0.198
E25 Adrenogenital disorders
0.000 0.803 0.196
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.804 0.196
E32 Diseases of thymus
0.000 0.804 0.196
E30 Disorders of puberty, not elsewhere classified
0.000 0.804 0.196
E21.4 Other specified disorders of parathyroid gland
0.000 0.804 0.196
E67.8 Other specified hyperalimentation
0.000 0.805 0.195
E67.3 Hypervitaminosis D
0.000 0.805 0.195
E67.2 Megavitamin-B6 syndrome
0.000 0.805 0.195
E67.1 Hypercarotenaemia
0.000 0.805 0.195
E67.0 Hypervitaminosis A
0.000 0.805 0.195
E21.2 Other hyperparathyroidism
0.000 0.811 0.189
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.812 0.188
E31 Polyglandular dysfunction
0.000 0.812 0.188
E24.8 Other Cushing's syndrome
0.000 0.818 0.182
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.818 0.182
E24.3 Ectopic ACTH syndrome
0.000 0.818 0.182
E24.1 Nelson's syndrome
0.000 0.818 0.182
E53 Deficiency of other B group vitamins
0.000 0.824 0.176
E28 Ovarian dysfunction
0.000 0.826 0.173
E51.2 Wernicke's encephalopathy
0.000 0.828 0.171
E51.9 Thiamine deficiency, unspecified
0.000 0.829 0.171
E51.8 Other manifestations of thiamine deficiency
0.000 0.829 0.171
E51.1 Beriberi
0.000 0.829 0.171
E50.9 Vitamin A deficiency, unspecified
0.000 0.829 0.171
E50.8 Other manifestations of vitamin A deficiency
0.000 0.829 0.171
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.829 0.171
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.829 0.171
E50.5 Vitamin A deficiency with night blindness
0.000 0.829 0.171
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.829 0.171
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.829 0.171
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.829 0.171
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.829 0.171
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.829 0.171
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.829 0.171
E64.8 Sequelae of other nutritional deficiencies
0.000 0.829 0.171
E64.3 Sequelae of rickets
0.000 0.829 0.171
E64.2 Sequelae of vitamin C deficiency
0.000 0.829 0.171
E64.1 Sequelae of vitamin A deficiency
0.000 0.829 0.171
E64.0 Sequelae of protein-energy malnutrition
0.000 0.829 0.171
E56.9 Vitamin deficiency, unspecified
0.000 0.838 0.162
E56.8 Deficiency of other vitamins
0.000 0.838 0.162
E56.0 Deficiency of vitamin E
0.000 0.838 0.162
E29 Testicular dysfunction
0.000 0.838 0.162
E63.8 Other specified nutritional deficiencies
0.000 0.845 0.155
E63.1 Imbalance of constituents of food intake
0.000 0.845 0.155
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.845 0.155
M45.X9 Ankylosing spondylitis (Site unspecified)
0.152 0.848 0.000
E34 Other endocrine disorders
0.000 0.848 0.152
E83 Disorders of mineral metabolism
0.147 0.849 0.004
E56.1 Deficiency of vitamin K
0.000 0.849 0.150
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.851 0.149
E55.0 Rickets, active
0.000 0.851 0.149
E61.9 Deficiency of nutrient element, unspecified
0.000 0.851 0.148
E61.8 Deficiency of other specified nutrient elements
0.000 0.851 0.148
E61.7 Deficiency of multiple nutrient elements
0.000 0.851 0.148
E61.6 Vanadium deficiency
0.000 0.851 0.148
E61.5 Molybdenum deficiency
0.000 0.851 0.148
E61.4 Chromium deficiency
0.000 0.851 0.148
E61.3 Manganese deficiency
0.000 0.851 0.148
E61.0 Copper deficiency
0.000 0.851 0.148
E20.9 Hypoparathyroidism, unspecified
0.000 0.855 0.145
E20.8 Other hypoparathyroidism
0.000 0.858 0.142
E20.1 Pseudohypoparathyroidism
0.000 0.858 0.142
E20.0 Idiopathic hypoparathyroidism
0.000 0.858 0.142
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.858 0.141
E25.9 Adrenogenital disorder, unspecified
0.000 0.859 0.141
E25.8 Other adrenogenital disorders
0.000 0.859 0.141
E61.1 Iron deficiency
0.000 0.859 0.141
E30.9 Disorder of puberty, unspecified
0.000 0.859 0.141
E30.8 Other disorders of puberty
0.000 0.859 0.141
E30.1 Precocious puberty
0.000 0.859 0.141
E30.0 Delayed puberty
0.000 0.859 0.141
E32.9 Disease of thymus, unspecified
0.000 0.859 0.141
E32.8 Other diseases of thymus
0.000 0.859 0.141
E32.1 Abscess of thymus
0.000 0.859 0.141
E32.0 Persistent hyperplasia of thymus
0.000 0.859 0.141
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.859 0.141
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.859 0.141
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.859 0.141
E53.9 Vitamin B deficiency, unspecified
0.000 0.863 0.137
E31.9 Polyglandular dysfunction, unspecified
0.000 0.865 0.135
E31.8 Other polyglandular dysfunction
0.000 0.865 0.135
E31.1 Polyglandular hyperfunction
0.000 0.865 0.135
E06.3 Autoimmune thyroiditis
0.001 0.866 0.133
E63.9 Nutritional deficiency, unspecified
0.000 0.867 0.132
E26 Hyperaldosteronism
0.000 0.870 0.130
E61.2 Magnesium deficiency
0.000 0.873 0.127
E31.0 Autoimmune polyglandular failure
0.000 0.873 0.126
E83.3 Disorders of phosphorus metabolism
0.125 0.874 0.001
E21.0 Primary hyperparathyroidism
0.000 0.874 0.126
E53.1 Pyridoxine deficiency
0.000 0.874 0.126
E53.0 Riboflavin deficiency
0.000 0.874 0.126
E28.9 Ovarian dysfunction, unspecified
0.000 0.875 0.124
E28.8 Other ovarian dysfunction
0.000 0.875 0.124
E28.1 Androgen excess
0.000 0.875 0.124
E28.0 Oestrogen excess
0.000 0.875 0.124
E28.2 Polycystic ovarian syndrome
0.000 0.879 0.121
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.880 0.120
E22 Hyperfunction of pituitary gland
0.000 0.881 0.119
E55.9 Vitamin D deficiency, unspecified
0.000 0.882 0.118
E29.9 Testicular dysfunction, unspecified
0.000 0.884 0.116
E29.8 Other testicular dysfunction
0.000 0.884 0.116
E29.0 Testicular hyperfunction
0.000 0.884 0.116
E11 Non-insulin-dependent diabetes mellitus
0.000 0.887 0.113
I83 Varicose veins of lower extremities
0.111 0.889 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.889 0.111
E34.5 Androgen resistance syndrome
0.000 0.891 0.109
E34.4 Constitutional tall stature
0.000 0.891 0.109
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.891 0.109
E34.1 Other hypersecretion of intestinal hormones
0.000 0.891 0.109
E83.8 Other disorders of mineral metabolism
0.105 0.891 0.003
E83.2 Disorders of zinc metabolism
0.105 0.891 0.003
E83.0 Disorders of copper metabolism
0.105 0.891 0.003
E83.9 Disorder of mineral metabolism, unspecified
0.104 0.893 0.003
E28.3 Primary ovarian failure
0.000 0.893 0.106
E34.9 Endocrine disorder, unspecified
0.000 0.899 0.100
E11.6 With other specified complications
0.000 0.901 0.099
E34.8 Other specified endocrine disorders
0.000 0.904 0.096
E14.9 Without complications
0.000 0.905 0.095
E34.0 Carcinoid syndrome
0.000 0.906 0.093
E26.8 Other hyperaldosteronism
0.000 0.906 0.093
E26.1 Secondary hyperaldosteronism
0.000 0.906 0.093
E22.1 Hyperprolactinaemia
0.000 0.912 0.088
E11.2 With renal complications
0.000 0.913 0.087
E11.0 With coma
0.000 0.913 0.086
E22.8 Other hyperfunction of pituitary gland
0.000 0.914 0.086
E26.9 Hyperaldosteronism, unspecified
0.001 0.917 0.082
E29.1 Testicular hypofunction
0.000 0.918 0.082
E11.1 With ketoacidosis
0.000 0.919 0.081
E11.7 With multiple complications
0.000 0.919 0.081
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.919 0.081
E23 Hypofunction and other disorders of pituitary gland
0.000 0.924 0.076
C15-C26 Malignant neoplasms of digestive organs
0.000 0.925 0.075
C20 Malignant neoplasm of rectum
0.000 0.925 0.075
I83.0 Varicose veins of lower extremities with ulcer
0.074 0.926 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.073 0.927 0.000
C15 Malignant neoplasm of oesophagus
0.000 0.928 0.072
M45 Ankylosing spondylitis
0.071 0.929 0.000
E11.8 With unspecified complications
0.000 0.933 0.067
C15.5 Lower third of oesophagus
0.000 0.934 0.066
C25 Malignant neoplasm of pancreas
0.000 0.935 0.065
E22.0 Acromegaly and pituitary gigantism
0.000 0.936 0.064
C15.4 Middle third of oesophagus
0.000 0.938 0.062
E23.7 Disorder of pituitary gland, unspecified
0.000 0.940 0.060
C17 Malignant neoplasm of small intestine
0.000 0.941 0.059
C15.9 Oesophagus, unspecified
0.000 0.942 0.058
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.943 0.057
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.943 0.057
M45.X2 Ankylosing spondylitis (Cervical region)
0.056 0.944 0.000
C17.0 Duodenum
0.000 0.944 0.056
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.944 0.056
C25.1 Body of pancreas
0.000 0.944 0.056
C25.3 Pancreatic duct
0.000 0.945 0.055
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.945 0.055
E23.1 Drug-induced hypopituitarism
0.000 0.945 0.055
C15.0 Cervical part of oesophagus
0.000 0.945 0.054
M45.X6 Ankylosing spondylitis (Lumbar region)
0.054 0.946 0.000
C25.2 Tail of pancreas
0.000 0.946 0.054
C15.8 Overlapping lesion of oesophagus
0.000 0.948 0.052
C15.2 Abdominal part of oesophagus
0.000 0.948 0.052
C25.4 Endocrine pancreas
0.000 0.949 0.051
C15.1 Thoracic part of oesophagus
0.000 0.949 0.051
E27 Other disorders of adrenal gland
0.000 0.949 0.051
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.051 0.949 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.051 0.949 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.051 0.949 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.051 0.949 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.051 0.949 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.051 0.949 0.000
E26.0 Primary hyperaldosteronism
0.001 0.949 0.050
C24.0 Extrahepatic bile duct
0.000 0.950 0.050
C25.8 Overlapping lesion of pancreas
0.000 0.950 0.050
S02.4 Fracture of malar and maxillary bones
0.000 0.951 0.049
E83.4 Disorders of magnesium metabolism
0.046 0.952 0.002
C15.3 Upper third of oesophagus
0.000 0.952 0.048
E04 Other non-toxic goitre
0.002 0.953 0.045
C25.9 Pancreas, unspecified
0.000 0.955 0.045
S02 Fracture of skull and facial bones
0.000 0.956 0.044
C25.7 Other parts of pancreas
0.000 0.957 0.043
C21 Malignant neoplasm of anus and anal canal
0.000 0.957 0.043
C17.8 Overlapping lesion of small intestine
0.000 0.958 0.042
C17.3 Meckel's diverticulum
0.000 0.958 0.042
C24.8 Overlapping lesion of biliary tract
0.000 0.960 0.040
C17.1 Jejunum
0.000 0.960 0.040
E11.3 With ophthalmic complications
0.000 0.960 0.040
E11.5 With peripheral circulatory complications
0.000 0.960 0.040
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.039 0.961 0.000
S02.0 Fracture of vault of skull
0.000 0.961 0.039
C24.9 Biliary tract, unspecified
0.000 0.961 0.039
E27.1 Primary adrenocortical insufficiency
0.000 0.962 0.038
E27.5 Adrenomedullary hyperfunction
0.000 0.963 0.037
E27.0 Other adrenocortical overactivity
0.000 0.963 0.037
E23.6 Other disorders of pituitary gland
0.001 0.964 0.036
S02.8 Fractures of other skull and facial bones
0.000 0.964 0.036
Z71.8 Other specified counselling
0.036 0.964 0.000
S02.3 Fracture of orbital floor
0.000 0.964 0.036
S02.00 Fracture of vault of skull (closed)
0.000 0.964 0.036
S02.6 Fracture of mandible
0.000 0.964 0.036
E23.2 Diabetes insipidus
0.000 0.965 0.035
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.965 0.034
S02.7 Multiple fractures involving skull and facial bones
0.000 0.966 0.034
E53.8 Deficiency of other specified B group vitamins
0.000 0.966 0.034
S02.5 Fracture of tooth
0.000 0.966 0.034
E04.8 Other specified non-toxic goitre
0.001 0.966 0.032
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.966 0.034
C23 Malignant neoplasm of gallbladder
0.000 0.967 0.033
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.967 0.033
S02.2 Fracture of nasal bones
0.000 0.967 0.033
E27.9 Disorder of adrenal gland, unspecified
0.000 0.967 0.032
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.968 0.032
C17.9 Small intestine, unspecified
0.000 0.969 0.031
E27.2 Addisonian crisis
0.000 0.969 0.031
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.969 0.031
C21.2 Cloacogenic zone
0.000 0.969 0.031
I83.1 Varicose veins of lower extremities with inflammation
0.031 0.969 0.000
S02.30 Fracture of orbital floor (closed)
0.000 0.969 0.031
C18.9 Colon, unspecified
0.000 0.970 0.030
S02.60 Fracture of mandible (closed)
0.000 0.970 0.030
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.971 0.029
C18 Malignant neoplasm of colon
0.000 0.971 0.029
S02.01 Fracture of vault of skull (open)
0.000 0.972 0.028
C17.2 Ileum
0.000 0.972 0.028
C18.1 Appendix
0.000 0.972 0.028
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.973 0.027
K90-K93 Other diseases of the digestive system
0.000 0.973 0.027
S02.21 Fracture of nasal bones (open)
0.000 0.973 0.027
S02.50 Fracture of tooth (closed)
0.000 0.973 0.027
E66 Obesity
0.000 0.973 0.027
S02.81 Fractures of other skull and facial bones (open)
0.000 0.974 0.026
S02.31 Fracture of orbital floor (open)
0.000 0.974 0.026
E70-E90 Metabolic disorders
0.002 0.974 0.024
S02.61 Fracture of mandible (open)
0.000 0.974 0.026
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.974 0.025
C26.8 Overlapping lesion of digestive system
0.000 0.975 0.025
C26.1 Spleen
0.000 0.975 0.025
S02.1 Fracture of base of skull
0.000 0.975 0.025
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.975 0.025
S02.51 Fracture of tooth (open)
0.000 0.975 0.024
E27.8 Other specified disorders of adrenal gland
0.000 0.976 0.024
C22.9 Liver, unspecified
0.000 0.976 0.024
E04.0 Non-toxic diffuse goitre
0.002 0.976 0.023
C21.0 Anus, unspecified
0.000 0.976 0.024
C22.7 Other specified carcinomas of liver
0.000 0.977 0.023
C22.4 Other sarcomas of liver
0.000 0.977 0.023
C22.3 Angiosarcoma of liver
0.000 0.977 0.023
C22.2 Hepatoblastoma
0.000 0.977 0.023
C25.0 Head of pancreas
0.000 0.977 0.023
C21.1 Anal canal
0.000 0.977 0.023
E23.0 Hypopituitarism
0.000 0.977 0.023
C24.1 Ampulla of Vater
0.001 0.978 0.022
C18.8 Overlapping lesion of colon
0.000 0.978 0.022
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.978 0.022
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.979 0.021
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.979 0.021
E78.2 Mixed hyperlipidaemia
0.000 0.979 0.021
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.980 0.020
E73 Lactose intolerance
0.001 0.980 0.019
C22.1 Intrahepatic bile duct carcinoma
0.000 0.980 0.020
E66.1 Drug-induced obesity
0.000 0.980 0.019
E11.4 With neurological complications
0.000 0.980 0.020
C18.4 Transverse colon
0.000 0.980 0.020
S02.20 Fracture of nasal bones (closed)
0.000 0.981 0.019
E74 Other disorders of carbohydrate metabolism
0.001 0.981 0.018
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.981 0.018
E78.5 Hyperlipidaemia, unspecified
0.000 0.981 0.019
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.981 0.019
E77 Disorders of glycoprotein metabolism
0.001 0.981 0.018
E76 Disorders of glycosaminoglycan metabolism
0.001 0.981 0.018
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.981 0.018
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.981 0.018
C26.9 Ill-defined sites within the digestive system
0.000 0.982 0.018
E78.1 Pure hyperglyceridaemia
0.000 0.982 0.018
E85 Amyloidosis
0.001 0.982 0.017
E70 Disorders of aromatic amino-acid metabolism
0.001 0.982 0.017
E88 Other metabolic disorders
0.001 0.982 0.017
S02.11 Fracture of base of skull (open)
0.000 0.982 0.017
E72 Other disorders of amino-acid metabolism
0.001 0.983 0.016
E79 Disorders of purine and pyrimidine metabolism
0.001 0.983 0.016
C26.0 Intestinal tract, part unspecified
0.000 0.983 0.017
E78.6 Lipoprotein deficiency
0.000 0.983 0.017
E84 Cystic fibrosis
0.001 0.983 0.016
E78.3 Hyperchylomicronaemia
0.000 0.983 0.017
E11.9 Without complications
0.000 0.983 0.017
H40.2 Primary angle-closure glaucoma
0.016 0.984 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.016 0.984 0.000
E73.9 Lactose intolerance, unspecified
0.001 0.985 0.015
C18.6 Descending colon
0.000 0.985 0.015
C18.7 Sigmoid colon
0.000 0.985 0.015
E66.0 Obesity due to excess calories
0.000 0.985 0.015
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.985 0.014
E88.9 Metabolic disorder, unspecified
0.000 0.985 0.014
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.015 0.985 0.000
E85.4 Organ-limited amyloidosis
0.000 0.985 0.014
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.985 0.015
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.985 0.014
K93.1 Megacolon in Chagas' disease
0.000 0.985 0.014
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.985 0.014
E75.5 Other lipid storage disorders
0.001 0.986 0.014
E73.8 Other lactose intolerance
0.001 0.986 0.014
E73.1 Secondary lactase deficiency
0.001 0.986 0.014
E73.0 Congenital lactase deficiency
0.001 0.986 0.014
E78.4 Other hyperlipidaemia
0.000 0.986 0.014
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.986 0.013
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.986 0.013
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.986 0.013
E74.2 Disorders of galactose metabolism
0.001 0.986 0.013
E74.1 Disorders of fructose metabolism
0.001 0.986 0.013
I89.0 Lymphoedema, not elsewhere classified
0.014 0.986 0.000
E75.6 Lipid storage disorder, unspecified
0.001 0.986 0.013
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.986 0.013
E75.3 Sphingolipidosis, unspecified
0.001 0.986 0.013
E75.1 Other gangliosidosis
0.001 0.986 0.013
E75.0 GM2 gangliosidosis
0.001 0.986 0.013
E74.0 Glycogen storage disease
0.001 0.986 0.013
E71.3 Disorders of fatty-acid metabolism
0.001 0.986 0.013
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.986 0.013
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.986 0.013
E71.0 Maple-syrup-urine disease
0.001 0.986 0.013
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.986 0.013
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.986 0.013
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.986 0.013
E76.2 Other mucopolysaccharidoses
0.001 0.986 0.013
E76.1 Mucopolysaccharidosis, type II
0.001 0.986 0.013
E76.0 Mucopolysaccharidosis, type I
0.001 0.986 0.013
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.986 0.013
E77.8 Other disorders of glycoprotein metabolism
0.001 0.986 0.013
E77.1 Defects in glycoprotein degradation
0.001 0.986 0.013
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.986 0.013
E75.2 Other sphingolipidosis
0.001 0.986 0.013
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.986 0.013
E85.3 Secondary systemic amyloidosis
0.001 0.986 0.013
E88.2 Lipomatosis, not elsewhere classified
0.000 0.987 0.013
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.987 0.013
E85.8 Other amyloidosis
0.001 0.987 0.013
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.987 0.013
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.987 0.013
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.987 0.013
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.013 0.987 0.000
C16 Malignant neoplasm of stomach
0.000 0.987 0.013
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.987 0.012
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.987 0.012
E70.2 Disorders of tyrosine metabolism
0.001 0.987 0.012
E70.1 Other hyperphenylalaninaemias
0.001 0.987 0.012
E70.0 Classical phenylketonuria
0.001 0.987 0.012
I86 Varicose veins of other sites
0.013 0.987 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.987 0.012
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.987 0.012
E72.5 Disorders of glycine metabolism
0.001 0.987 0.012
E72.4 Disorders of ornithine metabolism
0.001 0.987 0.012
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.987 0.012
E72.2 Disorders of urea cycle metabolism
0.001 0.987 0.012
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.987 0.012
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.987 0.012
E79.1 Lesch-Nyhan syndrome
0.001 0.987 0.012
E72.0 Disorders of amino-acid transport
0.001 0.987 0.011
E70.3 Albinism
0.001 0.988 0.011
E84.8 Cystic fibrosis with other manifestations
0.001 0.988 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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