TreeWAS – Variant ID: Affx-28396995

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.000	1.000
E10.9 Without complications	0.000	0.001	0.999
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.001	0.999
E10-E14 Diabetes mellitus	0.000	0.003	0.997
E16.2 Hypoglycaemia, unspecified	0.000	0.003	0.997
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.003	0.997
E16 Other disorders of pancreatic internal secretion	0.000	0.003	0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.003	0.997
E00-E07 Disorders of thyroid gland	0.000	0.004	0.996
E10.3 With ophthalmic complications	0.000	0.007	0.993
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.038	0.962
E10.2 With renal complications	0.000	0.044	0.956
E10.4 With neurological complications	0.000	0.115	0.885
E10.1 With ketoacidosis	0.000	0.120	0.880
E05.8 Other thyrotoxicosis	0.000	0.196	0.804
E16.1 Other hypoglycaemia	0.000	0.205	0.795
E13 Other specified diabetes mellitus	0.000	0.226	0.774
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.239	0.761
E10.7 With multiple complications	0.000	0.245	0.755
E40-E46 Malnutrition	0.000	0.256	0.743
E05.5 Thyroid crisis or storm	0.000	0.284	0.716
E05.4 Thyrotoxicosis factitia	0.000	0.284	0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.284	0.716
E12 Malnutrition-related diabetes mellitus	0.000	0.285	0.715
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.285	0.715
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.285	0.715
E16.4 Abnormal secretion of gastrin	0.000	0.285	0.715
E16.3 Increased secretion of glucagon	0.000	0.285	0.715
E15 Nondiabetic hypoglycaemic coma	0.000	0.285	0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.286	0.714
E00 Congenital iodine-deficiency syndrome	0.000	0.286	0.714
E10.0 With coma	0.000	0.287	0.713
E14 Unspecified diabetes mellitus	0.000	0.291	0.709
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.681	0.319	0.000
E10.6 With other specified complications	0.000	0.342	0.658
E10.5 With peripheral circulatory complications	0.000	0.357	0.643
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.358	0.642
E07 Other disorders of thyroid	0.000	0.366	0.634
E13.9 Without complications	0.000	0.378	0.622
E14.3 With ophthalmic complications	0.000	0.384	0.616
E06 Thyroiditis	0.000	0.401	0.599
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.412	0.587
E46 Unspecified protein-energy malnutrition	0.000	0.438	0.562
E14.1 With ketoacidosis	0.000	0.438	0.562
E13.8 With unspecified complications	0.000	0.445	0.555
E13.7 With multiple complications	0.000	0.445	0.555
E13.6 With other specified complications	0.000	0.445	0.555
E13.5 With peripheral circulatory complications	0.000	0.445	0.555
E13.4 With neurological complications	0.000	0.445	0.555
E13.2 With renal complications	0.000	0.445	0.555
E13.1 With ketoacidosis	0.000	0.445	0.555
E13.0 With coma	0.000	0.445	0.555
E03 Other hypothyroidism	0.000	0.453	0.547
E14.8 With unspecified complications	0.000	0.458	0.542
E13.3 With ophthalmic complications	0.000	0.458	0.541
E14.4 With neurological complications	0.000	0.463	0.537
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.467	0.533
E45 Retarded development following protein-energy malnutrition	0.000	0.467	0.533
E43 Unspecified severe protein-energy malnutrition	0.000	0.467	0.533
E42 Marasmic kwashiorkor	0.000	0.467	0.533
E41 Nutritional marasmus	0.000	0.467	0.533
E40 Kwashiorkor	0.000	0.467	0.533
E10.8 With unspecified complications	0.000	0.470	0.530
E14.6 With other specified complications	0.000	0.474	0.526
E12.9 Without complications	0.000	0.487	0.513
E12.8 With unspecified complications	0.000	0.487	0.513
E12.7 With multiple complications	0.000	0.487	0.513
E12.6 With other specified complications	0.000	0.487	0.513
E12.5 With peripheral circulatory complications	0.000	0.487	0.513
E12.4 With neurological complications	0.000	0.487	0.513
E12.3 With ophthalmic complications	0.000	0.487	0.513
E12.2 With renal complications	0.000	0.487	0.513
E12.1 With ketoacidosis	0.000	0.487	0.513
E12.0 With coma	0.000	0.487	0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.488	0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.488	0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.488	0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.488	0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.488	0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.488	0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.488	0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.488	0.512
E14.7 With multiple complications	0.000	0.492	0.508
E07.8 Other specified disorders of thyroid	0.000	0.498	0.502
E06.9 Thyroiditis, unspecified	0.000	0.501	0.499
E14.5 With peripheral circulatory complications	0.000	0.513	0.487
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.516	0.484
E14.0 With coma	0.000	0.521	0.479
E14.2 Withrenal complications	0.000	0.530	0.470
E07.1 Dyshormogenetic goitre	0.000	0.545	0.455
E07.0 Hypersecretion of calcitonin	0.000	0.545	0.455
K90 Intestinal malabsorption	0.000	0.560	0.440
E06.1 Subacute thyroiditis	0.000	0.563	0.437
E06.4 Drug-induced thyroiditis	0.000	0.570	0.430
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.570	0.430
E06.0 Acute thyroiditis	0.000	0.570	0.430
E06.5 Other chronic thyroiditis	0.000	0.583	0.417
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.587	0.413
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.596	0.404
E03.5 Myxoedema coma	0.000	0.608	0.392
E03.4 Atrophy of thyroid (acquired)	0.000	0.608	0.392
E03.3 Postinfectious hypothyroidism	0.000	0.608	0.392
E44.1 Mild protein-energy malnutrition	0.000	0.618	0.382
E44.0 Moderate protein-energy malnutrition	0.000	0.618	0.382
E03.1 Congenital hypothyroidism without goitre	0.000	0.618	0.382
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.638	0.362
E65-E68 Obesity and other hyperalimentation	0.000	0.639	0.361
E03.8 Other specified hypothyroidism	0.000	0.659	0.341
K90.3 Pancreatic steatorrhoea	0.000	0.684	0.315
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.684	0.315
K90.1 Tropical sprue	0.000	0.684	0.315
E50-E64 Other nutritional deficiencies	0.000	0.690	0.310
K90.8 Other intestinal malabsorption	0.000	0.692	0.308
R31 Unspecified haematuria	0.283	0.717	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.719	0.281
E20-E35 Disorders of other endocrine glands	0.000	0.733	0.267
E03.9 Hypothyroidism, unspecified	0.000	0.733	0.267
E67 Other hyperalimentation	0.000	0.741	0.259
E68 Sequelae of hyperalimentation	0.000	0.741	0.259
K90.9 Intestinal malabsorption, unspecified	0.000	0.742	0.258
E24 Cushing's syndrome	0.000	0.752	0.248
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.755	0.245
E21.3 Hyperparathyroidism, unspecified	0.000	0.763	0.237
E51 Thiamine deficiency	0.000	0.777	0.223
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.777	0.223
E50 Vitamin A deficiency	0.000	0.777	0.223
E60 Dietary zinc deficiency	0.000	0.777	0.223
E59 Dietary selenium deficiency	0.000	0.777	0.223
E52 Niacin deficiency [pellagra]	0.000	0.777	0.223
E65 Localised adiposity	0.000	0.778	0.221
E54 Ascorbic acid deficiency	0.000	0.781	0.219
E24.9 Cushing's syndrome, unspecified	0.000	0.785	0.215
E56 Other vitamin deficiencies	0.000	0.788	0.212
E24.0 Pituitary-dependent Cushing's disease	0.000	0.792	0.208
E58 Dietary calcium deficiency	0.000	0.794	0.205
E63 Other nutritional deficiencies	0.000	0.798	0.202
E24.2 Drug-induced Cushing's syndrome	0.000	0.804	0.196
E20 Hypoparathyroidism	0.000	0.806	0.194
E25 Adrenogenital disorders	0.000	0.808	0.192
E21.4 Other specified disorders of parathyroid gland	0.000	0.808	0.192
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.808	0.192
E32 Diseases of thymus	0.000	0.808	0.192
E30 Disorders of puberty, not elsewhere classified	0.000	0.808	0.192
E61 Deficiency of other nutrient elements	0.000	0.811	0.189
E55 Vitamin D deficiency	0.000	0.813	0.187
E67.8 Other specified hyperalimentation	0.000	0.814	0.186
E67.3 Hypervitaminosis D	0.000	0.814	0.186
E67.2 Megavitamin-B6 syndrome	0.000	0.814	0.186
E67.1 Hypercarotenaemia	0.000	0.814	0.186
E67.0 Hypervitaminosis A	0.000	0.814	0.186
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.815	0.185
E31 Polyglandular dysfunction	0.000	0.816	0.184
E24.8 Other Cushing's syndrome	0.000	0.822	0.178
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.822	0.178
E24.3 Ectopic ACTH syndrome	0.000	0.822	0.178
E24.1 Nelson's syndrome	0.000	0.822	0.178
E21.2 Other hyperparathyroidism	0.000	0.822	0.178
E28 Ovarian dysfunction	0.000	0.834	0.166
E53 Deficiency of other B group vitamins	0.000	0.835	0.165
E51.2 Wernicke's encephalopathy	0.000	0.839	0.160
E51.9 Thiamine deficiency, unspecified	0.000	0.840	0.160
E51.8 Other manifestations of thiamine deficiency	0.000	0.840	0.160
E51.1 Beriberi	0.000	0.840	0.160
E50.9 Vitamin A deficiency, unspecified	0.000	0.840	0.160
E50.8 Other manifestations of vitamin A deficiency	0.000	0.840	0.160
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.840	0.160
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.840	0.160
E50.5 Vitamin A deficiency with night blindness	0.000	0.840	0.160
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.840	0.160
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.840	0.160
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.840	0.160
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.840	0.160
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.840	0.160
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.840	0.160
E64.8 Sequelae of other nutritional deficiencies	0.000	0.840	0.160
E64.3 Sequelae of rickets	0.000	0.840	0.160
E64.2 Sequelae of vitamin C deficiency	0.000	0.840	0.160
E64.1 Sequelae of vitamin A deficiency	0.000	0.840	0.160
E64.0 Sequelae of protein-energy malnutrition	0.000	0.840	0.160
E29 Testicular dysfunction	0.000	0.841	0.158
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.848	0.152
E56.9 Vitamin deficiency, unspecified	0.000	0.848	0.152
E56.8 Deficiency of other vitamins	0.000	0.848	0.152
E56.0 Deficiency of vitamin E	0.000	0.848	0.152
E83 Disorders of mineral metabolism	0.148	0.849	0.004
M45.X9 Ankylosing spondylitis (Site unspecified)	0.150	0.850	0.000
E34 Other endocrine disorders	0.000	0.851	0.149
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.854	0.146
E63.8 Other specified nutritional deficiencies	0.000	0.855	0.145
E63.1 Imbalance of constituents of food intake	0.000	0.855	0.145
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.855	0.145
E20.9 Hypoparathyroidism, unspecified	0.000	0.858	0.142
E56.1 Deficiency of vitamin K	0.000	0.859	0.141
E20.8 Other hypoparathyroidism	0.000	0.860	0.139
E20.1 Pseudohypoparathyroidism	0.000	0.860	0.139
E20.0 Idiopathic hypoparathyroidism	0.000	0.860	0.139
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.861	0.139
I83 Varicose veins of lower extremities	0.138	0.862	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.862	0.138
E25.8 Other adrenogenital disorders	0.000	0.862	0.138
E30.9 Disorder of puberty, unspecified	0.000	0.862	0.138
E30.8 Other disorders of puberty	0.000	0.862	0.138
E30.1 Precocious puberty	0.000	0.862	0.138
E30.0 Delayed puberty	0.000	0.862	0.138
E32.9 Disease of thymus, unspecified	0.000	0.862	0.138
E32.8 Other diseases of thymus	0.000	0.862	0.138
E32.1 Abscess of thymus	0.000	0.862	0.138
E32.0 Persistent hyperplasia of thymus	0.000	0.862	0.138
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.862	0.138
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.862	0.138
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.862	0.138
E61.9 Deficiency of nutrient element, unspecified	0.000	0.864	0.135
E61.8 Deficiency of other specified nutrient elements	0.000	0.864	0.135
E61.7 Deficiency of multiple nutrient elements	0.000	0.864	0.135
E61.6 Vanadium deficiency	0.000	0.864	0.135
E61.5 Molybdenum deficiency	0.000	0.864	0.135
E61.4 Chromium deficiency	0.000	0.864	0.135
E61.3 Manganese deficiency	0.000	0.864	0.135
E61.0 Copper deficiency	0.000	0.864	0.135
E06.3 Autoimmune thyroiditis	0.001	0.865	0.134
E55.0 Rickets, active	0.000	0.866	0.134
E31.9 Polyglandular dysfunction, unspecified	0.000	0.868	0.132
E31.8 Other polyglandular dysfunction	0.000	0.868	0.132
E31.1 Polyglandular hyperfunction	0.000	0.868	0.132
E53.9 Vitamin B deficiency, unspecified	0.000	0.871	0.128
E26 Hyperaldosteronism	0.000	0.873	0.127
E83.3 Disorders of phosphorus metabolism	0.126	0.873	0.001
E61.1 Iron deficiency	0.000	0.876	0.124
E63.9 Nutritional deficiency, unspecified	0.000	0.876	0.124
E31.0 Autoimmune polyglandular failure	0.000	0.876	0.124
E11 Non-insulin-dependent diabetes mellitus	0.000	0.880	0.120
E28.9 Ovarian dysfunction, unspecified	0.000	0.881	0.119
E28.8 Other ovarian dysfunction	0.000	0.881	0.119
E28.1 Androgen excess	0.000	0.881	0.119
E28.0 Oestrogen excess	0.000	0.881	0.119
E21.0 Primary hyperparathyroidism	0.000	0.881	0.119
E53.1 Pyridoxine deficiency	0.000	0.881	0.118
E53.0 Riboflavin deficiency	0.000	0.881	0.118
E22 Hyperfunction of pituitary gland	0.000	0.883	0.117
E61.2 Magnesium deficiency	0.000	0.884	0.116
E29.9 Testicular dysfunction, unspecified	0.000	0.886	0.114
E29.8 Other testicular dysfunction	0.000	0.886	0.114
E29.0 Testicular hyperfunction	0.000	0.886	0.114
E28.2 Polycystic ovarian syndrome	0.000	0.888	0.112
E34.3 Short stature, not elsewhere classified	0.000	0.891	0.109
E83.8 Other disorders of mineral metabolism	0.106	0.891	0.003
E83.2 Disorders of zinc metabolism	0.106	0.891	0.003
E83.0 Disorders of copper metabolism	0.106	0.891	0.003
E83.9 Disorder of mineral metabolism, unspecified	0.105	0.892	0.003
E34.5 Androgen resistance syndrome	0.000	0.893	0.107
E34.4 Constitutional tall stature	0.000	0.893	0.107
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.893	0.107
E34.1 Other hypersecretion of intestinal hormones	0.000	0.893	0.107
E11.6 With other specified complications	0.000	0.893	0.107
E28.3 Primary ovarian failure	0.000	0.898	0.102
C15-C26 Malignant neoplasms of digestive organs	0.000	0.900	0.100
C20 Malignant neoplasm of rectum	0.000	0.900	0.100
E34.9 Endocrine disorder, unspecified	0.000	0.901	0.099
E55.9 Vitamin D deficiency, unspecified	0.000	0.902	0.098
C15 Malignant neoplasm of oesophagus	0.000	0.902	0.098
I83.0 Varicose veins of lower extremities with ulcer	0.095	0.905	0.000
E34.8 Other specified endocrine disorders	0.000	0.906	0.094
E34.0 Carcinoid syndrome	0.000	0.908	0.092
E11.0 With coma	0.000	0.908	0.092
E26.8 Other hyperaldosteronism	0.000	0.908	0.091
E26.1 Secondary hyperaldosteronism	0.000	0.908	0.091
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.090	0.910	0.000
C15.5 Lower third of oesophagus	0.000	0.910	0.090
E11.2 With renal complications	0.000	0.911	0.089
C25 Malignant neoplasm of pancreas	0.000	0.913	0.087
E22.1 Hyperprolactinaemia	0.000	0.913	0.086
E11.1 With ketoacidosis	0.000	0.914	0.086
E11.7 With multiple complications	0.000	0.914	0.086
C15.4 Middle third of oesophagus	0.000	0.915	0.085
E14.9 Without complications	0.000	0.915	0.085
E22.8 Other hyperfunction of pituitary gland	0.000	0.916	0.084
E26.9 Hyperaldosteronism, unspecified	0.001	0.919	0.081
E29.1 Testicular hypofunction	0.000	0.919	0.080
C15.9 Oesophagus, unspecified	0.000	0.920	0.080
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.920	0.079
C17 Malignant neoplasm of small intestine	0.000	0.921	0.079
C17.0 Duodenum	0.000	0.925	0.075
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.925	0.075
C25.1 Body of pancreas	0.000	0.926	0.074
C15.0 Cervical part of oesophagus	0.000	0.926	0.074
C25.3 Pancreatic duct	0.000	0.927	0.073
E23 Hypofunction and other disorders of pituitary gland	0.000	0.928	0.072
E11.8 With unspecified complications	0.000	0.929	0.071
C15.8 Overlapping lesion of oesophagus	0.000	0.930	0.070
C15.2 Abdominal part of oesophagus	0.000	0.930	0.070
C25.2 Tail of pancreas	0.000	0.930	0.070
Z71.8 Other specified counselling	0.069	0.931	0.000
M45 Ankylosing spondylitis	0.069	0.931	0.000
C15.1 Thoracic part of oesophagus	0.000	0.931	0.069
C25.4 Endocrine pancreas	0.000	0.932	0.068
C24.0 Extrahepatic bile duct	0.000	0.933	0.067
C25.8 Overlapping lesion of pancreas	0.000	0.934	0.066
C15.3 Upper third of oesophagus	0.000	0.936	0.064
E22.0 Acromegaly and pituitary gigantism	0.000	0.937	0.063
C25.9 Pancreas, unspecified	0.000	0.938	0.062
C25.7 Other parts of pancreas	0.000	0.942	0.057
E23.7 Disorder of pituitary gland, unspecified	0.000	0.943	0.057
C17.8 Overlapping lesion of small intestine	0.000	0.943	0.056
C17.3 Meckel's diverticulum	0.000	0.943	0.056
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.944	0.056
M45.X2 Ankylosing spondylitis (Cervical region)	0.055	0.945	0.000
C21 Malignant neoplasm of anus and anal canal	0.000	0.946	0.054
C24.8 Overlapping lesion of biliary tract	0.000	0.946	0.054
C17.1 Jejunum	0.000	0.946	0.054
M45.X6 Ankylosing spondylitis (Lumbar region)	0.053	0.947	0.000
C24.9 Biliary tract, unspecified	0.000	0.948	0.052
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.948	0.052
E23.1 Drug-induced hypopituitarism	0.000	0.948	0.052
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.050	0.950	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.050	0.950	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.050	0.950	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.050	0.950	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.050	0.950	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.050	0.950	0.000
E26.0 Primary hyperaldosteronism	0.001	0.950	0.049
E27 Other disorders of adrenal gland	0.000	0.951	0.048
E04 Other non-toxic goitre	0.002	0.951	0.046
E83.4 Disorders of magnesium metabolism	0.046	0.952	0.002
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.954	0.046
C23 Malignant neoplasm of gallbladder	0.000	0.955	0.044
E11.3 With ophthalmic complications	0.000	0.957	0.043
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.957	0.043
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.957	0.043
C17.9 Small intestine, unspecified	0.000	0.958	0.042
E11.5 With peripheral circulatory complications	0.000	0.960	0.040
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.961	0.039
C21.2 Cloacogenic zone	0.000	0.961	0.039
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.038	0.962	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.038	0.962	0.000
C17.2 Ileum	0.000	0.963	0.037
E27.1 Primary adrenocortical insufficiency	0.000	0.964	0.036
C18.9 Colon, unspecified	0.000	0.965	0.035
C18 Malignant neoplasm of colon	0.000	0.965	0.035
E27.5 Adrenomedullary hyperfunction	0.000	0.965	0.035
E27.0 Other adrenocortical overactivity	0.000	0.965	0.035
E04.8 Other specified non-toxic goitre	0.002	0.965	0.033
E23.6 Other disorders of pituitary gland	0.001	0.965	0.034
C26.8 Overlapping lesion of digestive system	0.000	0.967	0.033
C26.1 Spleen	0.000	0.967	0.033
C18.1 Appendix	0.000	0.967	0.033
E53.8 Deficiency of other specified B group vitamins	0.000	0.967	0.033
S02.4 Fracture of malar and maxillary bones	0.000	0.967	0.033
C22.9 Liver, unspecified	0.000	0.968	0.032
E23.2 Diabetes insipidus	0.000	0.969	0.031
E27.9 Disorder of adrenal gland, unspecified	0.000	0.969	0.031
C22.7 Other specified carcinomas of liver	0.000	0.969	0.031
C22.4 Other sarcomas of liver	0.000	0.969	0.031
C22.3 Angiosarcoma of liver	0.000	0.969	0.031
C22.2 Hepatoblastoma	0.000	0.969	0.031
C25.0 Head of pancreas	0.000	0.969	0.031
E27.2 Addisonian crisis	0.000	0.970	0.030
C24.1 Ampulla of Vater	0.001	0.970	0.029
C21.0 Anus, unspecified	0.000	0.971	0.029
S02 Fracture of skull and facial bones	0.000	0.971	0.029
C21.1 Anal canal	0.000	0.972	0.028
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.028	0.972	0.000
E66 Obesity	0.000	0.972	0.028
K90-K93 Other diseases of the digestive system	0.000	0.973	0.027
E70-E90 Metabolic disorders	0.002	0.973	0.025
C18.8 Overlapping lesion of colon	0.000	0.973	0.027
C22.1 Intrahepatic bile duct carcinoma	0.000	0.974	0.026
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.026	0.974	0.000
S02.0 Fracture of vault of skull	0.000	0.975	0.025
E04.0 Non-toxic diffuse goitre	0.002	0.975	0.023
S02.8 Fractures of other skull and facial bones	0.000	0.975	0.025
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.975	0.024
C26.9 Ill-defined sites within the digestive system	0.000	0.975	0.024
I89.0 Lymphoedema, not elsewhere classified	0.024	0.976	0.000
S02.3 Fracture of orbital floor	0.000	0.976	0.024
C18.4 Transverse colon	0.000	0.976	0.024
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.977	0.023
C26.0 Intestinal tract, part unspecified	0.000	0.977	0.023
S02.6 Fracture of mandible	0.000	0.977	0.023
S02.00 Fracture of vault of skull (closed)	0.000	0.977	0.023
I86 Varicose veins of other sites	0.023	0.977	0.000
S02.5 Fracture of tooth	0.000	0.977	0.023
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.023	0.977	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.977	0.023
E78.2 Mixed hyperlipidaemia	0.000	0.977	0.022
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.978	0.022
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.978	0.022
E27.8 Other specified disorders of adrenal gland	0.000	0.978	0.022
E23.0 Hypopituitarism	0.000	0.978	0.022
I85 Oesophageal varices	0.022	0.978	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.979	0.021
I81 Portal vein thrombosis	0.021	0.979	0.000
E11.4 With neurological complications	0.000	0.979	0.021
E73 Lactose intolerance	0.001	0.979	0.020
E11.9 Without complications	0.000	0.980	0.020
S02.30 Fracture of orbital floor (closed)	0.000	0.980	0.020
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.980	0.020
E66.1 Drug-induced obesity	0.000	0.980	0.020
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.001	0.980	0.019
I87 Other disorders of veins	0.020	0.980	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.980	0.020
S02.2 Fracture of nasal bones	0.000	0.980	0.020
E74 Other disorders of carbohydrate metabolism	0.001	0.980	0.019
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.980	0.020
E77 Disorders of glycoprotein metabolism	0.001	0.980	0.018
E76 Disorders of glycosaminoglycan metabolism	0.001	0.980	0.018
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.001	0.980	0.018
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.001	0.980	0.018
I86.8 Varicose veins of other specified sites	0.020	0.980	0.000
I86.4 Gastric varices	0.019	0.981	0.000
I85.9 Oesophageal varices without bleeding	0.019	0.981	0.000
C18.6 Descending colon	0.000	0.981	0.019
E85 Amyloidosis	0.001	0.981	0.018
H40.2 Primary angle-closure glaucoma	0.019	0.981	0.000
E70 Disorders of aromatic amino-acid metabolism	0.002	0.981	0.018
S02.60 Fracture of mandible (closed)	0.000	0.981	0.019
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.981	0.019
I89.1 Lymphangitis	0.019	0.981	0.000
S02.50 Fracture of tooth (closed)	0.000	0.981	0.019
E78.6 Lipoprotein deficiency	0.000	0.981	0.019
S02.01 Fracture of vault of skull (open)	0.000	0.982	0.018
E72 Other disorders of amino-acid metabolism	0.002	0.982	0.017
E79 Disorders of purine and pyrimidine metabolism	0.002	0.982	0.017
E88 Other metabolic disorders	0.001	0.982	0.018
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.982	0.018
S02.81 Fractures of other skull and facial bones (open)	0.000	0.982	0.018
E78.3 Hyperchylomicronaemia	0.000	0.982	0.018
E84 Cystic fibrosis	0.002	0.982	0.016
S02.31 Fracture of orbital floor (open)	0.000	0.983	0.017
I87.8 Other specified disorders of veins	0.017	0.983	0.000
I88 Nonspecific lymphadenitis	0.017	0.983	0.000
I86.3 Vulval varices	0.017	0.983	0.000
C18.7 Sigmoid colon	0.000	0.983	0.017
C16 Malignant neoplasm of stomach	0.000	0.983	0.017
I86.2 Pelvic varices	0.017	0.983	0.000
S02.61 Fracture of mandible (open)	0.000	0.983	0.017
I86.0 Sublingual varices	0.017	0.983	0.000
S02.51 Fracture of tooth (open)	0.000	0.983	0.017
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.983	0.016
I82 Other venous embolism and thrombosis	0.016	0.984	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.984	0.016
E66.0 Obesity due to excess calories	0.000	0.984	0.016
S02.1 Fracture of base of skull	0.000	0.984	0.016
E73.9 Lactose intolerance, unspecified	0.001	0.984	0.015
E78.4 Other hyperlipidaemia	0.000	0.985	0.015
I87.9 Disorder of vein, unspecified	0.015	0.985	0.000
E85.4 Organ-limited amyloidosis	0.001	0.985	0.015
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.985	0.015
E88.9 Metabolic disorder, unspecified	0.000	0.985	0.015
E75.5 Other lipid storage disorders	0.001	0.985	0.014
E73.8 Other lactose intolerance	0.001	0.985	0.014
E73.1 Secondary lactase deficiency	0.001	0.985	0.014
E73.0 Congenital lactase deficiency	0.001	0.985	0.014
E74.3 Other disorders of intestinal carbohydrate absorption	0.001	0.985	0.014
C18.3 Hepatic flexure	0.000	0.985	0.015
E75.6 Lipid storage disorder, unspecified	0.001	0.985	0.014
E75.4 Neuronal ceroid lipofuscinosis	0.001	0.985	0.014
E75.3 Sphingolipidosis, unspecified	0.001	0.985	0.014
E75.1 Other gangliosidosis	0.001	0.985	0.014
E75.0 GM2 gangliosidosis	0.001	0.985	0.014
I87.0 Postphlebitic syndrome	0.014	0.985	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.001	0.985	0.014
E74.8 Other specified disorders of carbohydrate metabolism	0.001	0.985	0.014
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.001	0.985	0.014
E74.2 Disorders of galactose metabolism	0.001	0.985	0.014
E74.1 Disorders of fructose metabolism	0.001	0.985	0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.985	0.014
K93.1 Megacolon in Chagas' disease	0.000	0.985	0.014
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.985	0.014
E71.3 Disorders of fatty-acid metabolism	0.001	0.986	0.013
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.001	0.986	0.013
E71.1 Other disorders of branched-chain amino-acid metabolism	0.001	0.986	0.013
E71.0 Maple-syrup-urine disease	0.001	0.986	0.013
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.001	0.986	0.013
E76.8 Other disorders of glucosaminoglycan metabolism	0.001	0.986	0.013
E76.3 Mucopolysaccharidosis, unspecified	0.001	0.986	0.013
E76.2 Other mucopolysaccharidoses	0.001	0.986	0.013
E76.1 Mucopolysaccharidosis, type II	0.001	0.986	0.013
E76.0 Mucopolysaccharidosis, type I	0.001	0.986	0.013
E77.9 Disorder of glycoprotein metabolism, unspecified	0.001	0.986	0.013
E77.8 Other disorders of glycoprotein metabolism	0.001	0.986	0.013
E77.1 Defects in glycoprotein degradation	0.001	0.986	0.013
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.001	0.986	0.013
E75.2 Other sphingolipidosis	0.001	0.986	0.013
E85.3 Secondary systemic amyloidosis	0.001	0.986	0.013
E74.0 Glycogen storage disease	0.001	0.986	0.013
E85.8 Other amyloidosis	0.001	0.986	0.013
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.986	0.013
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.986	0.013
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.986	0.013
I77.6 Arteritis, unspecified	0.000	0.986	0.014
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.986	0.014
I77 Other disorders of arteries and arterioles	0.000	0.986	0.014
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.001	0.986	0.013
E70.8 Other disorders of aromatic amino-acid metabolism	0.001	0.986	0.013
E70.2 Disorders of tyrosine metabolism	0.001	0.986	0.013
E70.1 Other hyperphenylalaninaemias	0.001	0.986	0.013
E70.0 Classical phenylketonuria	0.001	0.986	0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations