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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-28441669
log Bayes Factor = 98.3349
Chromosome 6   position 31,084,075  (GRCh37) Explore Affx-28441669 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M45 Ankylosing spondylitis
0.995 0.005 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.993 0.007 0.000
L40.0 Psoriasis vulgaris
0.986 0.014 0.000
G35 Multiple sclerosis
0.000 0.018 0.982
E06 Thyroiditis
0.000 0.033 0.967
E06.3 Autoimmune thyroiditis
0.000 0.054 0.946
L40.8 Other psoriasis
0.936 0.064 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.099 0.901
E10-E14 Diabetes mellitus
0.000 0.112 0.888
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.115 0.885
L40.4 Guttate psoriasis
0.877 0.123 0.000
E10.3 With ophthalmic complications
0.000 0.124 0.876
E10.1 With ketoacidosis
0.000 0.135 0.865
E10.2 With renal complications
0.000 0.153 0.847
L40.1 Generalised pustular psoriasis
0.842 0.158 0.000
E10.4 With neurological complications
0.000 0.170 0.830
M45.X2 Ankylosing spondylitis (Cervical region)
0.821 0.179 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.213 0.787
E14 Unspecified diabetes mellitus
0.000 0.237 0.763
M45.X6 Ankylosing spondylitis (Lumbar region)
0.755 0.245 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.745 0.254 0.000
E40-E46 Malnutrition
0.000 0.267 0.733
E14.3 With ophthalmic complications
0.000 0.281 0.719
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.714 0.286 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.714 0.286 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.714 0.286 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.714 0.286 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.714 0.286 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.287 0.713
E06.9 Thyroiditis, unspecified
0.000 0.295 0.705
E05.8 Other thyrotoxicosis
0.000 0.297 0.703
E06.5 Other chronic thyroiditis
0.000 0.298 0.702
E03.1 Congenital hypothyroidism without goitre
0.000 0.298 0.701
M35.0 Sicca syndrome [Sjogren]
0.000 0.299 0.701
E10.5 With peripheral circulatory complications
0.000 0.302 0.698
E06.4 Drug-induced thyroiditis
0.000 0.307 0.693
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.307 0.693
E06.0 Acute thyroiditis
0.000 0.307 0.693
L40.3 Pustulosis palmaris et plantaris
0.676 0.324 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.324 0.676
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.343 0.657
E10.0 With coma
0.000 0.350 0.650
E12 Malnutrition-related diabetes mellitus
0.000 0.363 0.636
E10.7 With multiple complications
0.000 0.368 0.632
E06.1 Subacute thyroiditis
0.000 0.372 0.628
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.372 0.628
E10.9 Without complications
0.000 0.375 0.625
E46 Unspecified protein-energy malnutrition
0.000 0.377 0.623
E03.8 Other specified hypothyroidism
0.000 0.377 0.623
E07 Other disorders of thyroid
0.000 0.380 0.620
E27.1 Primary adrenocortical insufficiency
0.000 0.380 0.620
E10.6 With other specified complications
0.000 0.383 0.617
E10.8 With unspecified complications
0.000 0.384 0.616
E14.8 With unspecified complications
0.000 0.386 0.614
E14.2 Withrenal complications
0.000 0.394 0.606
E14.6 With other specified complications
0.000 0.402 0.597
E27 Other disorders of adrenal gland
0.000 0.405 0.595
E20-E35 Disorders of other endocrine glands
0.000 0.405 0.594
E14.1 With ketoacidosis
0.000 0.426 0.574
E14.5 With peripheral circulatory complications
0.000 0.433 0.566
E14.7 With multiple complications
0.000 0.453 0.547
E14.0 With coma
0.000 0.453 0.547
E27.2 Addisonian crisis
0.000 0.467 0.533
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.474 0.525
E45 Retarded development following protein-energy malnutrition
0.000 0.474 0.525
E43 Unspecified severe protein-energy malnutrition
0.000 0.474 0.525
E42 Marasmic kwashiorkor
0.000 0.474 0.525
E41 Nutritional marasmus
0.000 0.474 0.525
E40 Kwashiorkor
0.000 0.474 0.525
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E04 Other non-toxic goitre
0.000 0.492 0.508
E13 Other specified diabetes mellitus
0.000 0.506 0.494
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.510 0.490
E07.8 Other specified disorders of thyroid
0.000 0.529 0.471
E20 Hypoparathyroidism
0.000 0.532 0.468
E04.0 Non-toxic diffuse goitre
0.000 0.537 0.462
E12.9 Without complications
0.000 0.543 0.456
E12.8 With unspecified complications
0.000 0.543 0.456
E12.7 With multiple complications
0.000 0.543 0.456
E12.6 With other specified complications
0.000 0.543 0.456
E12.5 With peripheral circulatory complications
0.000 0.543 0.456
E12.4 With neurological complications
0.000 0.543 0.456
E12.3 With ophthalmic complications
0.000 0.543 0.456
E12.2 With renal complications
0.000 0.543 0.456
E12.1 With ketoacidosis
0.000 0.543 0.456
E12.0 With coma
0.000 0.543 0.456
E07.1 Dyshormogenetic goitre
0.000 0.555 0.445
E07.0 Hypersecretion of calcitonin
0.000 0.555 0.445
E27.5 Adrenomedullary hyperfunction
0.000 0.573 0.426
E27.0 Other adrenocortical overactivity
0.000 0.573 0.426
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.574 0.426
E32 Diseases of thymus
0.000 0.574 0.426
E31 Polyglandular dysfunction
0.000 0.574 0.426
E30 Disorders of puberty, not elsewhere classified
0.000 0.574 0.426
E28 Ovarian dysfunction
0.000 0.576 0.424
K90 Intestinal malabsorption
0.000 0.579 0.421
E50-E64 Other nutritional deficiencies
0.000 0.604 0.396
L40-L45 Papulosquamous disorders
0.389 0.611 0.000
E13.3 With ophthalmic complications
0.000 0.612 0.388
R31 Unspecified haematuria
0.381 0.619 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.623 0.377
E44.1 Mild protein-energy malnutrition
0.000 0.623 0.377
E44.0 Moderate protein-energy malnutrition
0.000 0.623 0.377
G36 Other acute disseminated demyelination
0.000 0.623 0.376
E15 Nondiabetic hypoglycaemic coma
0.000 0.631 0.369
G37 Other demyelinating diseases of central nervous system
0.000 0.633 0.367
E04.8 Other specified non-toxic goitre
0.000 0.636 0.364
E28.3 Primary ovarian failure
0.000 0.641 0.359
E25 Adrenogenital disorders
0.001 0.645 0.354
E13.8 With unspecified complications
0.000 0.646 0.354
E13.7 With multiple complications
0.000 0.646 0.354
E13.6 With other specified complications
0.000 0.646 0.354
E13.5 With peripheral circulatory complications
0.000 0.646 0.354
E13.4 With neurological complications
0.000 0.646 0.354
E13.2 With renal complications
0.000 0.646 0.354
E13.1 With ketoacidosis
0.000 0.646 0.354
E13.0 With coma
0.000 0.646 0.354
E26 Hyperaldosteronism
0.000 0.654 0.345
E20.8 Other hypoparathyroidism
0.000 0.664 0.335
E20.1 Pseudohypoparathyroidism
0.000 0.664 0.335
E20.0 Idiopathic hypoparathyroidism
0.000 0.664 0.335
E14.4 With neurological complications
0.001 0.669 0.331
E34 Other endocrine disorders
0.000 0.673 0.327
E65-E68 Obesity and other hyperalimentation
0.000 0.674 0.325
K90.8 Other intestinal malabsorption
0.000 0.678 0.322
L41 Parapsoriasis
0.321 0.679 0.000
E24 Cushing's syndrome
0.000 0.680 0.320
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.682 0.318
E30.9 Disorder of puberty, unspecified
0.000 0.694 0.306
E30.8 Other disorders of puberty
0.000 0.694 0.306
E30.1 Precocious puberty
0.000 0.694 0.306
E30.0 Delayed puberty
0.000 0.694 0.306
E31.9 Polyglandular dysfunction, unspecified
0.000 0.694 0.306
E31.8 Other polyglandular dysfunction
0.000 0.694 0.306
E31.1 Polyglandular hyperfunction
0.000 0.694 0.306
E31.0 Autoimmune polyglandular failure
0.000 0.694 0.306
E32.9 Disease of thymus, unspecified
0.000 0.694 0.306
E32.8 Other diseases of thymus
0.000 0.694 0.306
E32.1 Abscess of thymus
0.000 0.694 0.306
E32.0 Persistent hyperplasia of thymus
0.000 0.694 0.306
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.694 0.306
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.694 0.306
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.694 0.306
E28.9 Ovarian dysfunction, unspecified
0.000 0.696 0.304
E28.8 Other ovarian dysfunction
0.000 0.696 0.304
E28.1 Androgen excess
0.000 0.696 0.304
E28.0 Oestrogen excess
0.000 0.696 0.304
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.698 0.302
K90.3 Pancreatic steatorrhoea
0.000 0.698 0.302
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.698 0.302
K90.1 Tropical sprue
0.000 0.698 0.302
E27.8 Other specified disorders of adrenal gland
0.000 0.698 0.301
E07.9 Disorder of thyroid, unspecified
0.000 0.699 0.301
E51 Thiamine deficiency
0.000 0.699 0.301
E53 Deficiency of other B group vitamins
0.000 0.703 0.297
M45-M49 Spondylopathies
0.296 0.704 0.000
G36.0 Neuromyelitis optica [Devic]
0.000 0.705 0.295
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.706 0.294
E54 Ascorbic acid deficiency
0.000 0.707 0.293
L42 Pityriasis rosea
0.293 0.707 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.715 0.285
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.716 0.284
E63 Other nutritional deficiencies
0.000 0.716 0.284
E50 Vitamin A deficiency
0.000 0.716 0.284
E60 Dietary zinc deficiency
0.000 0.716 0.284
E59 Dietary selenium deficiency
0.000 0.716 0.284
E52 Niacin deficiency [pellagra]
0.000 0.716 0.284
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.716 0.284
K90.9 Intestinal malabsorption, unspecified
0.000 0.717 0.283
L44 Other papulosquamous disorders
0.282 0.718 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.279 0.721 0.000
M07.3 Other psoriatic arthropathies
0.277 0.723 0.000
L41.1 Pityriasis lichenoides chronica
0.273 0.727 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.272 0.728 0.000
E29 Testicular dysfunction
0.002 0.729 0.269
M35 Other systemic involvement of connective tissue
0.000 0.730 0.270
G36.9 Acute disseminated demyelination, unspecified
0.000 0.730 0.270
G36.8 Other specified acute disseminated demyelination
0.000 0.730 0.270
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.730 0.270
M07.39 Other psoriatic arthropathies (Site unspecified)
0.267 0.733 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.736 0.264
G37.4 Subacute necrotising myelitis
0.000 0.736 0.264
G37.2 Central pontine myelinolysis
0.000 0.736 0.264
G37.1 Central demyelination of corpus callosum
0.000 0.736 0.264
G37.0 Diffuse sclerosis
0.000 0.736 0.264
E27.9 Disorder of adrenal gland, unspecified
0.001 0.737 0.263
E56 Other vitamin deficiencies
0.000 0.737 0.262
E23 Hypofunction and other disorders of pituitary gland
0.001 0.739 0.261
E04.9 Non-toxic goitre, unspecified
0.000 0.741 0.259
E21.0 Primary hyperparathyroidism
0.000 0.742 0.258
E25.9 Adrenogenital disorder, unspecified
0.001 0.745 0.254
E25.8 Other adrenogenital disorders
0.001 0.745 0.254
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.253 0.747 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.751 0.249
E26.8 Other hyperaldosteronism
0.000 0.752 0.248
E26.1 Secondary hyperaldosteronism
0.000 0.752 0.248
E04.2 Non-toxic multinodular goitre
0.000 0.753 0.247
E26.9 Hyperaldosteronism, unspecified
0.000 0.754 0.245
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.759 0.240
E24.2 Drug-induced Cushing's syndrome
0.000 0.761 0.239
E58 Dietary calcium deficiency
0.000 0.762 0.238
M49 Spondylopathies in diseases classified elsewhere
0.237 0.763 0.000
M35.7 Hypermobility syndrome
0.000 0.763 0.237
E34.5 Androgen resistance syndrome
0.000 0.765 0.234
E34.4 Constitutional tall stature
0.000 0.765 0.234
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.765 0.234
E34.1 Other hypersecretion of intestinal hormones
0.000 0.765 0.234
E34.9 Endocrine disorder, unspecified
0.000 0.766 0.233
E67 Other hyperalimentation
0.000 0.766 0.233
E68 Sequelae of hyperalimentation
0.000 0.766 0.233
M07.34 Other psoriatic arthropathies (Hand)
0.233 0.766 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.767 0.233
E53.9 Vitamin B deficiency, unspecified
0.000 0.767 0.233
E51.2 Wernicke's encephalopathy
0.000 0.768 0.232
L41.9 Parapsoriasis, unspecified
0.230 0.769 0.000
L41.8 Other parapsoriasis
0.230 0.769 0.000
L41.5 Retiform parapsoriasis
0.230 0.769 0.000
L41.4 Large plaque parapsoriasis
0.230 0.769 0.000
L41.3 Small plaque parapsoriasis
0.230 0.769 0.000
L41.2 Lymphomatoid papulosis
0.230 0.769 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.230 0.769 0.000
M07.38 Other psoriatic arthropathies (Other)
0.230 0.770 0.000
E24.8 Other Cushing's syndrome
0.000 0.770 0.230
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.770 0.229
E24.3 Ectopic ACTH syndrome
0.000 0.770 0.229
E24.1 Nelson's syndrome
0.000 0.770 0.229
E23.2 Diabetes insipidus
0.000 0.775 0.224
E61 Deficiency of other nutrient elements
0.000 0.776 0.224
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.780 0.220
M07.31 Other psoriatic arthropathies (Shoulder region)
0.218 0.781 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.782 0.217
E51.9 Thiamine deficiency, unspecified
0.000 0.784 0.216
E51.8 Other manifestations of thiamine deficiency
0.000 0.784 0.216
E51.1 Beriberi
0.000 0.784 0.216
E34.8 Other specified endocrine disorders
0.000 0.786 0.214
E53.1 Pyridoxine deficiency
0.000 0.787 0.213
E53.0 Riboflavin deficiency
0.000 0.787 0.213
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.787 0.213
M35.1 Other overlap syndromes
0.000 0.790 0.210
L44.0 Pityriasis rubra pilaris
0.206 0.794 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.794 0.206
E22 Hyperfunction of pituitary gland
0.000 0.795 0.204
E21.2 Other hyperparathyroidism
0.000 0.795 0.204
E50.9 Vitamin A deficiency, unspecified
0.000 0.796 0.204
E50.8 Other manifestations of vitamin A deficiency
0.000 0.796 0.204
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.796 0.204
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.796 0.204
E50.5 Vitamin A deficiency with night blindness
0.000 0.796 0.204
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.796 0.204
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.796 0.204
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.796 0.204
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.796 0.204
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.796 0.204
E63.9 Nutritional deficiency, unspecified
0.000 0.796 0.204
E63.8 Other specified nutritional deficiencies
0.000 0.796 0.204
E63.1 Imbalance of constituents of food intake
0.000 0.796 0.204
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.796 0.204
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.796 0.204
E64.8 Sequelae of other nutritional deficiencies
0.000 0.796 0.204
E64.3 Sequelae of rickets
0.000 0.796 0.204
E64.2 Sequelae of vitamin C deficiency
0.000 0.796 0.204
E64.1 Sequelae of vitamin A deficiency
0.000 0.796 0.204
E64.0 Sequelae of protein-energy malnutrition
0.000 0.796 0.204
L44.9 Papulosquamous disorder, unspecified
0.202 0.797 0.000
L44.8 Other specified papulosquamous disorders
0.202 0.797 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.202 0.797 0.000
L44.3 Lichen ruber moniliformis
0.202 0.797 0.000
L44.2 Lichen striatus
0.202 0.797 0.000
L44.1 Lichen nitidus
0.202 0.797 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.202 0.797 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.202 0.798 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.800 0.199
M07.33 Other psoriatic arthropathies (Forearm)
0.199 0.801 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.199 0.801 0.000
E65 Localised adiposity
0.000 0.802 0.198
E28.2 Polycystic ovarian syndrome
0.000 0.802 0.198
E55 Vitamin D deficiency
0.000 0.802 0.197
E24.9 Cushing's syndrome, unspecified
0.000 0.803 0.197
M49.5 Collapsed vertebra in diseases classified elsewhere
0.196 0.804 0.000
M47 Spondylosis
0.195 0.805 0.000
E29.9 Testicular dysfunction, unspecified
0.002 0.805 0.193
E29.8 Other testicular dysfunction
0.002 0.805 0.193
E29.0 Testicular hyperfunction
0.002 0.805 0.193
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.806 0.194
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.806 0.194
M35.5 Multifocal fibrosclerosis
0.000 0.806 0.194
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.806 0.194
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.806 0.194
E56.9 Vitamin deficiency, unspecified
0.000 0.811 0.188
E56.8 Deficiency of other vitamins
0.000 0.811 0.188
E56.0 Deficiency of vitamin E
0.000 0.811 0.188
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.812 0.187
E23.1 Drug-induced hypopituitarism
0.001 0.812 0.187
M35.8 Other specified systemic involvement of connective tissue
0.000 0.816 0.184
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.817 0.182
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.821 0.179
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.821 0.179
E16.4 Abnormal secretion of gastrin
0.000 0.821 0.179
E16.3 Increased secretion of glucagon
0.000 0.821 0.179
M47.8 Other spondylosis
0.179 0.821 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.825 0.175
E34.0 Carcinoid syndrome
0.001 0.826 0.173
E61.2 Magnesium deficiency
0.000 0.827 0.173
E23.6 Other disorders of pituitary gland
0.001 0.828 0.172
E26.0 Primary hyperaldosteronism
0.001 0.828 0.171
M49.8 Spondylopathy in other diseases classified elsewhere
0.170 0.830 0.000
M49.4 Neuropathic spondylopathy
0.170 0.830 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.170 0.830 0.000
M49.2 Enterobacterial spondylitis
0.170 0.830 0.000
M49.1 Brucella spondylitis
0.170 0.830 0.000
M49.0 Tuberculosis of spine
0.170 0.830 0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.168 0.832 0.000
E67.8 Other specified hyperalimentation
0.000 0.832 0.167
E67.3 Hypervitaminosis D
0.000 0.832 0.167
E67.2 Megavitamin-B6 syndrome
0.000 0.832 0.167
E67.1 Hypercarotenaemia
0.000 0.832 0.167
E67.0 Hypervitaminosis A
0.000 0.832 0.167
E56.1 Deficiency of vitamin K
0.000 0.833 0.167
M07 Psoriatic and enteropathic arthropathies
0.166 0.834 0.000
M46 Other inflammatory spondylopathies
0.166 0.834 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.166 0.834 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.839 0.161
E61.8 Deficiency of other specified nutrient elements
0.000 0.839 0.161
E61.7 Deficiency of multiple nutrient elements
0.000 0.839 0.161
E61.6 Vanadium deficiency
0.000 0.839 0.161
E61.5 Molybdenum deficiency
0.000 0.839 0.161
E61.4 Chromium deficiency
0.000 0.839 0.161
E61.3 Manganese deficiency
0.000 0.839 0.161
E61.0 Copper deficiency
0.000 0.839 0.161
M35.2 Behcet's disease
0.000 0.841 0.159
E24.0 Pituitary-dependent Cushing's disease
0.001 0.842 0.157
M47.89 Other spondylosis (Site unspecified)
0.156 0.844 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.845 0.155
M46.4 Discitis, unspecified
0.151 0.849 0.000
L43 Lichen planus
0.150 0.849 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.150 0.850 0.000
E22.8 Other hyperfunction of pituitary gland
0.000 0.853 0.147
M48 Other spondylopathies
0.146 0.854 0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.145 0.855 0.000
M47.2 Other spondylosis with radiculopathy
0.142 0.858 0.000
E55.0 Rickets, active
0.000 0.858 0.142
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.858 0.141
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.140 0.859 0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.140 0.859 0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.140 0.859 0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.140 0.859 0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.140 0.859 0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.140 0.859 0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.140 0.859 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.140 0.860 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.861 0.139
M47.84 Other spondylosis (Thoracic region)
0.137 0.862 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.135 0.865 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.135 0.865 0.000
E23.7 Disorder of pituitary gland, unspecified
0.001 0.867 0.132
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.130 0.870 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.129 0.871 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.128 0.872 0.000
E16.1 Other hypoglycaemia
0.000 0.874 0.126
M47.85 Other spondylosis (Thoracolumbar region)
0.126 0.874 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.123 0.877 0.000
M47.1 Other spondylosis with myelopathy
0.123 0.877 0.000
M49.09 Tuberculosis of spine (Site unspecified)
0.122 0.878 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.122 0.878 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.122 0.878 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.122 0.878 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.122 0.878 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.122 0.878 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.122 0.878 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.122 0.878 0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.122 0.878 0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.122 0.878 0.000
M49.19 Brucella spondylitis (Site unspecified)
0.122 0.878 0.000
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.122 0.878 0.000
M49.17 Brucella spondylitis (Lumbosacral region)
0.122 0.878 0.000
M49.16 Brucella spondylitis (Lumbar region)
0.122 0.878 0.000
M49.15 Brucella spondylitis (Thoracolumbar region)
0.122 0.878 0.000
M49.14 Brucella spondylitis (Thoracic region)
0.122 0.878 0.000
M49.13 Brucella spondylitis (Cervicothoracic region)
0.122 0.878 0.000
M49.12 Brucella spondylitis (Cervical region)
0.122 0.878 0.000
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.122 0.878 0.000
M49.10 Brucella spondylitis (Multiple sites in spine)
0.122 0.878 0.000
M49.29 Enterobacterial spondylitis (Site unspecified)
0.122 0.878 0.000
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)
0.122 0.878 0.000
M49.27 Enterobacterial spondylitis (Lumbosacral region)
0.122 0.878 0.000
M49.26 Enterobacterial spondylitis (Lumbar region)
0.122 0.878 0.000
M49.25 Enterobacterial spondylitis (Thoracolumbar region)
0.122 0.878 0.000
M49.24 Enterobacterial spondylitis (Thoracic region)
0.122 0.878 0.000
M49.23 Enterobacterial spondylitis (Cervicothoracic region)
0.122 0.878 0.000
M49.22 Enterobacterial spondylitis (Cervical region)
0.122 0.878 0.000
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)
0.122 0.878 0.000
M49.20 Enterobacterial spondylitis (Multiple sites in spine)
0.122 0.878 0.000
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)
0.122 0.878 0.000
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)
0.122 0.878 0.000
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)
0.122 0.878 0.000
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)
0.122 0.878 0.000
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)
0.122 0.878 0.000
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)
0.122 0.878 0.000
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)
0.122 0.878 0.000
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)
0.122 0.878 0.000
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)
0.122 0.878 0.000
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)
0.122 0.878 0.000
M49.49 Neuropathic spondylopathy (Site unspecified)
0.122 0.878 0.000
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)
0.122 0.878 0.000
M49.47 Neuropathic spondylopathy (Lumbosacral region)
0.122 0.878 0.000
M49.46 Neuropathic spondylopathy (Lumbar region)
0.122 0.878 0.000
M49.45 Neuropathic spondylopathy (Thoracolumbar region)
0.122 0.878 0.000
M49.44 Neuropathic spondylopathy (Thoracic region)
0.122 0.878 0.000
M49.43 Neuropathic spondylopathy (Cervicothoracic region)
0.122 0.878 0.000
M49.42 Neuropathic spondylopathy (Cervical region)
0.122 0.878 0.000
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)
0.122 0.878 0.000
M49.40 Neuropathic spondylopathy (Multiple sites in spine)
0.122 0.878 0.000
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)
0.122 0.878 0.000
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)
0.122 0.878 0.000
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)
0.122 0.878 0.000
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)
0.122 0.878 0.000
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)
0.122 0.878 0.000
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)
0.122 0.878 0.000
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)
0.122 0.878 0.000
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)
0.122 0.878 0.000
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)
0.122 0.878 0.000
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)
0.122 0.878 0.000
E13.9 Without complications
0.001 0.880 0.119
M07.5 Arthropathy in ulcerative colitis
0.119 0.880 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.119 0.880 0.000
M07.2 Psoriatic spondylitis
0.119 0.880 0.000
M07.1 Arthritis mutilans
0.119 0.880 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.119 0.880 0.000
M46.8 Other specified inflammatory spondylopathies
0.119 0.881 0.000
M46.5 Other infective spondylopathies
0.119 0.881 0.000
M46.42 Discitis, unspecified (Cervical region)
0.118 0.882 0.000
M35.3 Polymyalgia rheumatica
0.000 0.882 0.118
M07.6 Other enteropathic arthropathies
0.118 0.882 0.000
M46.0 Spinal enthesopathy
0.117 0.882 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.117 0.883 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.115 0.885 0.000
M48.9 Spondylopathy, unspecified
0.113 0.887 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.888 0.112
E22.0 Acromegaly and pituitary gigantism
0.000 0.888 0.112
E16.2 Hypoglycaemia, unspecified
0.000 0.888 0.112
M46.1 Sacro-iliitis, not elsewhere classified
0.110 0.890 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.110 0.890 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.110 0.890 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.108 0.892 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.108 0.892 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.108 0.892 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.108 0.892 0.000
L43.3 Subacute (active) lichen planus
0.108 0.892 0.000
L43.2 Lichenoid drug reaction
0.108 0.892 0.000
L43.1 Bullous lichen planus
0.108 0.892 0.000
L43.0 Hypertrophic lichen planus
0.108 0.892 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.106 0.894 0.000
E22.1 Hyperprolactinaemia
0.001 0.895 0.104
M48.4 Fatigue fracture of vertebra
0.105 0.895 0.000
M48.3 Traumatic spondylopathy
0.105 0.895 0.000
M48.2 Kissing spine
0.105 0.895 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.105 0.895 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.102 0.898 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.102 0.898 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.102 0.898 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.102 0.898 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.102 0.898 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.102 0.898 0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)
0.101 0.899 0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)
0.101 0.899 0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)
0.101 0.899 0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)
0.101 0.899 0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)
0.101 0.899 0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)
0.101 0.899 0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)
0.101 0.899 0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)
0.101 0.899 0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)
0.101 0.899 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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