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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-28442697
log Bayes Factor = 56.1801
Chromosome 6   position 31,130,502  (GRCh37) Explore Affx-28442697 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
E11.9 Without complications
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
E78.0 Pure hypercholesterolaemia
0.000 0.011 0.989
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.015 0.985
E70-E90 Metabolic disorders
0.000 0.020 0.980
G35 Multiple sclerosis
0.980 0.020 0.000
L40 Psoriasis
0.000 0.060 0.940
E14 Unspecified diabetes mellitus
0.000 0.075 0.925
E11.0 With coma
0.000 0.121 0.879
L40.5 Arthropathic psoriasis
0.000 0.125 0.875
E78.8 Other disorders of lipoprotein metabolism
0.000 0.131 0.869
E07 Other disorders of thyroid
0.000 0.147 0.853
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.164 0.836
E10.3 With ophthalmic complications
0.000 0.170 0.830
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.188 0.812
E14.3 With ophthalmic complications
0.000 0.189 0.811
E78.2 Mixed hyperlipidaemia
0.000 0.193 0.807
E03.8 Other specified hypothyroidism
0.000 0.197 0.803
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.200 0.800
L40.0 Psoriasis vulgaris
0.000 0.206 0.794
E11.1 With ketoacidosis
0.000 0.222 0.778
L40.8 Other psoriasis
0.000 0.223 0.777
E14.9 Without complications
0.000 0.224 0.776
E79 Disorders of purine and pyrimidine metabolism
0.000 0.234 0.766
E74 Other disorders of carbohydrate metabolism
0.000 0.238 0.762
E78.4 Other hyperlipidaemia
0.000 0.241 0.759
E07.9 Disorder of thyroid, unspecified
0.000 0.241 0.759
K90 Intestinal malabsorption
0.000 0.250 0.750
E10.8 With unspecified complications
0.000 0.250 0.750
E10.6 With other specified complications
0.000 0.260 0.740
E11.2 With renal complications
0.000 0.261 0.739
E78.1 Pure hyperglyceridaemia
0.000 0.268 0.732
E14.5 With peripheral circulatory complications
0.000 0.271 0.729
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
G35-G37 Demyelinating diseases of the central nervous system
0.716 0.284 0.000
E13 Other specified diabetes mellitus
0.000 0.286 0.714
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
E10.0 With coma
0.000 0.291 0.709
E78.6 Lipoprotein deficiency
0.000 0.293 0.707
E78.3 Hyperchylomicronaemia
0.000 0.293 0.706
L40.1 Generalised pustular psoriasis
0.000 0.295 0.705
E10.1 With ketoacidosis
0.000 0.296 0.704
E77 Disorders of glycoprotein metabolism
0.000 0.297 0.703
E76 Disorders of glycosaminoglycan metabolism
0.000 0.297 0.703
E72 Other disorders of amino-acid metabolism
0.000 0.297 0.703
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.297 0.703
E70 Disorders of aromatic amino-acid metabolism
0.000 0.297 0.703
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.297 0.703
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.310 0.690
E14.4 With neurological complications
0.000 0.311 0.689
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.314 0.686
E83 Disorders of mineral metabolism
0.654 0.314 0.032
E40-E46 Malnutrition
0.000 0.316 0.684
E78.5 Hyperlipidaemia, unspecified
0.000 0.319 0.681
E16 Other disorders of pancreatic internal secretion
0.000 0.322 0.678
E84 Cystic fibrosis
0.000 0.324 0.676
L40.2 Acrodermatitis continua
0.000 0.326 0.674
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.332 0.668
L40.4 Guttate psoriasis
0.000 0.332 0.668
E14.1 With ketoacidosis
0.000 0.335 0.665
E14.7 With multiple complications
0.000 0.337 0.663
E14.0 With coma
0.000 0.337 0.663
E14.2 Withrenal complications
0.000 0.344 0.656
E14.6 With other specified complications
0.000 0.346 0.654
G37 Other demyelinating diseases of central nervous system
0.649 0.351 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.360 0.639
E03.1 Congenital hypothyroidism without goitre
0.000 0.366 0.634
E80.6 Other disorders of bilirubin metabolism
0.000 0.371 0.629
E11.8 With unspecified complications
0.000 0.376 0.624
E14.8 With unspecified complications
0.000 0.377 0.623
E05.8 Other thyrotoxicosis
0.000 0.379 0.621
E10.2 With renal complications
0.000 0.386 0.613
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.387 0.613
E07.1 Dyshormogenetic goitre
0.000 0.388 0.611
E07.0 Hypersecretion of calcitonin
0.000 0.388 0.611
K90.9 Intestinal malabsorption, unspecified
0.000 0.390 0.610
E80.2 Other porphyria
0.000 0.390 0.610
E10.5 With peripheral circulatory complications
0.000 0.397 0.603
E80.4 Gilbert's syndrome
0.000 0.400 0.600
G37.9 Demyelinating disease of central nervous system, unspecified
0.587 0.413 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.418 0.582
E07.8 Other specified disorders of thyroid
0.000 0.418 0.582
C83.3 Large cell (diffuse)
0.000 0.420 0.580
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.427 0.573
E80.5 Crigler-Najjar syndrome
0.000 0.427 0.573
E80.3 Defects of catalase and peroxydase
0.000 0.427 0.573
E80.0 Hereditary erythropoietic porphyria
0.000 0.427 0.573
E83.3 Disorders of phosphorus metabolism
0.561 0.430 0.009
E88 Other metabolic disorders
0.000 0.431 0.569
E80.1 Porphyria cutanea tarda
0.000 0.432 0.568
E73 Lactose intolerance
0.000 0.433 0.566
L40.3 Pustulosis palmaris et plantaris
0.000 0.448 0.552
E16.2 Hypoglycaemia, unspecified
0.000 0.449 0.551
L40-L45 Papulosquamous disorders
0.000 0.450 0.550
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.450 0.549
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.450 0.549
E79.1 Lesch-Nyhan syndrome
0.000 0.450 0.549
G36 Other acute disseminated demyelination
0.549 0.450 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.454 0.546
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.454 0.546
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.454 0.546
E74.2 Disorders of galactose metabolism
0.000 0.454 0.546
E74.1 Disorders of fructose metabolism
0.000 0.454 0.546
E13.9 Without complications
0.000 0.460 0.540
K90.3 Pancreatic steatorrhoea
0.000 0.462 0.538
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.462 0.538
K90.1 Tropical sprue
0.000 0.462 0.538
K90.8 Other intestinal malabsorption
0.000 0.463 0.537
E83.9 Disorder of mineral metabolism, unspecified
0.516 0.464 0.020
E16.1 Other hypoglycaemia
0.000 0.472 0.528
E11.5 With peripheral circulatory complications
0.000 0.473 0.527
G37.8 Other specified demyelinating diseases of central nervous system
0.523 0.477 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.477 0.523
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E13.8 With unspecified complications
0.000 0.488 0.512
E13.7 With multiple complications
0.000 0.488 0.512
E13.6 With other specified complications
0.000 0.488 0.512
E13.5 With peripheral circulatory complications
0.000 0.488 0.512
E13.4 With neurological complications
0.000 0.488 0.512
E13.2 With renal complications
0.000 0.488 0.512
E13.1 With ketoacidosis
0.000 0.488 0.512
E13.0 With coma
0.000 0.488 0.512
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.496 0.504
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.496 0.504
E70.3 Albinism
0.000 0.496 0.504
E70.2 Disorders of tyrosine metabolism
0.000 0.496 0.504
E70.1 Other hyperphenylalaninaemias
0.000 0.496 0.504
E70.0 Classical phenylketonuria
0.000 0.496 0.504
E71.3 Disorders of fatty-acid metabolism
0.000 0.496 0.504
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.496 0.504
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.496 0.504
E71.0 Maple-syrup-urine disease
0.000 0.496 0.504
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.496 0.504
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.496 0.504
E72.5 Disorders of glycine metabolism
0.000 0.496 0.504
E72.4 Disorders of ornithine metabolism
0.000 0.496 0.504
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.496 0.504
E72.2 Disorders of urea cycle metabolism
0.000 0.496 0.504
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.496 0.504
E72.0 Disorders of amino-acid transport
0.000 0.496 0.504
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.496 0.504
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.496 0.504
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.496 0.504
E76.2 Other mucopolysaccharidoses
0.000 0.496 0.504
E76.1 Mucopolysaccharidosis, type II
0.000 0.496 0.504
E76.0 Mucopolysaccharidosis, type I
0.000 0.496 0.504
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.496 0.504
E77.8 Other disorders of glycoprotein metabolism
0.000 0.496 0.504
E77.1 Defects in glycoprotein degradation
0.000 0.496 0.504
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.496 0.504
E75.6 Lipid storage disorder, unspecified
0.000 0.508 0.492
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.508 0.492
E75.3 Sphingolipidosis, unspecified
0.000 0.508 0.492
E75.2 Other sphingolipidosis
0.000 0.508 0.492
E75.1 Other gangliosidosis
0.000 0.508 0.492
E75.0 GM2 gangliosidosis
0.000 0.508 0.492
E83.8 Other disorders of mineral metabolism
0.469 0.508 0.023
E83.2 Disorders of zinc metabolism
0.469 0.508 0.023
E83.0 Disorders of copper metabolism
0.469 0.508 0.023
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.509 0.491
E45 Retarded development following protein-energy malnutrition
0.000 0.509 0.491
E43 Unspecified severe protein-energy malnutrition
0.000 0.509 0.491
E42 Marasmic kwashiorkor
0.000 0.509 0.491
E41 Nutritional marasmus
0.000 0.509 0.491
E40 Kwashiorkor
0.000 0.509 0.491
E10.4 With neurological complications
0.000 0.509 0.490
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.510 0.489
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.514 0.486
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.514 0.486
E16.4 Abnormal secretion of gastrin
0.000 0.514 0.486
E16.3 Increased secretion of glucagon
0.000 0.514 0.486
E74.0 Glycogen storage disease
0.000 0.515 0.485
E84.8 Cystic fibrosis with other manifestations
0.000 0.515 0.485
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.515 0.485
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.515 0.485
E75.5 Other lipid storage disorders
0.000 0.524 0.475
E13.3 With ophthalmic complications
0.000 0.524 0.475
G37.5 Concentric sclerosis [Balo]
0.466 0.534 0.000
G37.4 Subacute necrotising myelitis
0.466 0.534 0.000
G37.2 Central pontine myelinolysis
0.466 0.534 0.000
G37.1 Central demyelination of corpus callosum
0.466 0.534 0.000
G37.0 Diffuse sclerosis
0.466 0.534 0.000
L43 Lichen planus
0.000 0.535 0.465
E11.6 With other specified complications
0.000 0.537 0.463
E84.9 Cystic fibrosis, unspecified
0.000 0.541 0.458
E46 Unspecified protein-energy malnutrition
0.000 0.542 0.458
E11.4 With neurological complications
0.000 0.552 0.448
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.445 0.554 0.000
E88.2 Lipomatosis, not elsewhere classified
0.000 0.556 0.444
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.568 0.431
E85 Amyloidosis
0.001 0.569 0.430
G36.0 Neuromyelitis optica [Devic]
0.430 0.569 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.572 0.428
L43.9 Lichen planus, unspecified
0.000 0.576 0.424
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.578 0.422
C83 Diffuse non-Hodgkin's lymphoma
0.005 0.589 0.406
E88.9 Metabolic disorder, unspecified
0.000 0.592 0.408
E88.8 Other specified metabolic disorders
0.000 0.592 0.408
L42 Pityriasis rosea
0.000 0.593 0.407
E73.8 Other lactose intolerance
0.000 0.594 0.406
E73.1 Secondary lactase deficiency
0.000 0.594 0.406
E73.0 Congenital lactase deficiency
0.000 0.594 0.406
E88.3 Tumour lysis syndrome
0.000 0.597 0.403
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.001 0.601 0.398
E89.4 Postprocedural ovarian failure
0.000 0.602 0.398
L44 Other papulosquamous disorders
0.000 0.605 0.395
L41 Parapsoriasis
0.000 0.605 0.395
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.605 0.395
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.605 0.394
G36.9 Acute disseminated demyelination, unspecified
0.394 0.606 0.000
G36.8 Other specified acute disseminated demyelination
0.394 0.606 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.394 0.606 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.007 0.607 0.386
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.609 0.391
C85.1 B-cell lymphoma, unspecified
0.000 0.610 0.390
E06 Thyroiditis
0.000 0.613 0.386
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.002 0.619 0.379
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.624 0.376
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.625 0.375
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.625 0.375
E89.5 Postprocedural testicular hypofunction
0.000 0.625 0.375
E89.1 Postprocedural hypoinsulinaemia
0.000 0.625 0.375
E83.4 Disorders of magnesium metabolism
0.350 0.638 0.011
E89.3 Postprocedural hypopituitarism
0.000 0.641 0.359
E44.1 Mild protein-energy malnutrition
0.000 0.648 0.352
E44.0 Moderate protein-energy malnutrition
0.000 0.648 0.352
E20-E35 Disorders of other endocrine glands
0.000 0.651 0.348
L43.3 Subacute (active) lichen planus
0.000 0.667 0.333
L43.2 Lichenoid drug reaction
0.000 0.667 0.333
L43.1 Bullous lichen planus
0.000 0.667 0.333
L43.0 Hypertrophic lichen planus
0.000 0.667 0.333
E65-E68 Obesity and other hyperalimentation
0.000 0.673 0.327
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.676 0.324
C83.7 Burkitt's tumour
0.003 0.683 0.314
E89.2 Postprocedural hypoparathyroidism
0.000 0.685 0.315
E28 Ovarian dysfunction
0.000 0.686 0.314
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.691 0.309
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.691 0.309
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.691 0.309
C82.2 Large cell, follicular
0.001 0.693 0.306
E83.5 Disorders of calcium metabolism
0.297 0.700 0.003
E28.2 Polycystic ovarian syndrome
0.000 0.702 0.298
C83.6 Undifferentiated (diffuse)
0.004 0.705 0.291
C83.5 Lymphoblastic (diffuse)
0.004 0.705 0.291
C83.4 Immunoblastic (diffuse)
0.004 0.705 0.291
C83.2 Mixed small and large cell (diffuse)
0.004 0.705 0.291
C82.3 Follicular lymphoma grade IIIa
0.001 0.705 0.293
E85.8 Other amyloidosis
0.001 0.706 0.293
E50-E64 Other nutritional deficiencies
0.000 0.709 0.291
E85.9 Amyloidosis, unspecified
0.000 0.711 0.288
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.001 0.714 0.285
C85.0 Lymphosarcoma
0.001 0.714 0.285
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.003 0.716 0.281
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.716 0.284
C81 Hodgkin's disease
0.004 0.716 0.280
L41.9 Parapsoriasis, unspecified
0.000 0.717 0.283
L41.8 Other parapsoriasis
0.000 0.717 0.283
L41.5 Retiform parapsoriasis
0.000 0.717 0.283
L41.4 Large plaque parapsoriasis
0.000 0.717 0.283
L41.3 Small plaque parapsoriasis
0.000 0.717 0.283
L41.2 Lymphomatoid papulosis
0.000 0.717 0.283
L41.1 Pityriasis lichenoides chronica
0.000 0.717 0.283
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.717 0.283
L44.9 Papulosquamous disorder, unspecified
0.000 0.717 0.283
L44.8 Other specified papulosquamous disorders
0.000 0.717 0.283
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.717 0.283
L44.3 Lichen ruber moniliformis
0.000 0.717 0.283
L44.2 Lichen striatus
0.000 0.717 0.283
L44.1 Lichen nitidus
0.000 0.717 0.283
L44.0 Pityriasis rubra pilaris
0.000 0.717 0.283
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.005 0.718 0.277
C86 Other specified types of T/NK-cell lymphoma
0.005 0.718 0.277
M06.9 Rheumatoid arthritis, unspecified
0.000 0.719 0.281
E24 Cushing's syndrome
0.000 0.720 0.280
E23 Hypofunction and other disorders of pituitary gland
0.000 0.721 0.279
C84 Peripheral and cutaneous T-cell lymphomas
0.004 0.721 0.275
E06.5 Other chronic thyroiditis
0.000 0.723 0.277
E06.4 Drug-induced thyroiditis
0.000 0.723 0.277
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.723 0.277
E06.0 Acute thyroiditis
0.000 0.723 0.277
C85.7 Other specified types of non-Hodgkin's lymphoma
0.001 0.724 0.276
C82.6 Cutaneous follicle centre lymphoma
0.002 0.727 0.272
C82.5 Diffuse follicle centre lymphoma
0.002 0.727 0.272
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.001 0.728 0.270
E73.9 Lactose intolerance, unspecified
0.001 0.730 0.270
L43.8 Other lichen planus
0.000 0.735 0.265
E06.1 Subacute thyroiditis
0.000 0.736 0.263
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.737 0.263
C82.0 Small cleaved cell, follicular
0.002 0.740 0.259
C94 Other leukaemias of specified cell type
0.006 0.741 0.253
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.743 0.257
C82.4 Follicular lymphoma grade IIIb
0.002 0.747 0.252
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.747 0.253
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.750 0.250
E32 Diseases of thymus
0.000 0.750 0.250
E31 Polyglandular dysfunction
0.000 0.750 0.250
E30 Disorders of puberty, not elsewhere classified
0.000 0.750 0.250
E25 Adrenogenital disorders
0.000 0.750 0.250
E85.4 Organ-limited amyloidosis
0.001 0.752 0.248
C93 Monocytic leukaemia
0.006 0.759 0.235
C81.9 Hodgkin's disease, unspecified
0.001 0.760 0.239
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.762 0.238
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.763 0.237
C83.1 Small cleaved cell (diffuse)
0.004 0.764 0.232
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.765 0.235
E67 Other hyperalimentation
0.000 0.765 0.235
E68 Sequelae of hyperalimentation
0.000 0.765 0.235
E85.3 Secondary systemic amyloidosis
0.001 0.769 0.230
E26 Hyperaldosteronism
0.000 0.769 0.231
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.771 0.229
E21.3 Hyperparathyroidism, unspecified
0.000 0.772 0.228
E23.7 Disorder of pituitary gland, unspecified
0.000 0.773 0.227
E28.9 Ovarian dysfunction, unspecified
0.000 0.775 0.225
E28.8 Other ovarian dysfunction
0.000 0.775 0.225
E28.1 Androgen excess
0.000 0.775 0.225
E28.0 Oestrogen excess
0.000 0.775 0.225
E24.2 Drug-induced Cushing's syndrome
0.000 0.776 0.224
C88 Malignant immunoproliferative diseases
0.006 0.778 0.216
E23.2 Diabetes insipidus
0.000 0.780 0.220
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.780 0.220
E11.3 With ophthalmic complications
0.000 0.781 0.219
C91 Lymphoid leukaemia
0.004 0.786 0.210
E24.9 Cushing's syndrome, unspecified
0.000 0.789 0.211
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.790 0.210
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.791 0.209
E63 Other nutritional deficiencies
0.000 0.791 0.209
E50 Vitamin A deficiency
0.000 0.791 0.209
E60 Dietary zinc deficiency
0.000 0.791 0.209
E59 Dietary selenium deficiency
0.000 0.791 0.209
E54 Ascorbic acid deficiency
0.000 0.791 0.209
E52 Niacin deficiency [pellagra]
0.000 0.791 0.209
C84.5 Other and unspecified T-cell lymphomas
0.002 0.793 0.204
E20 Hypoparathyroidism
0.000 0.795 0.205
E56 Other vitamin deficiencies
0.000 0.795 0.204
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.003 0.796 0.201
C81.3 Lymphocytic depletion
0.003 0.796 0.201
C81.2 Mixed cellularity
0.003 0.796 0.201
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.004 0.797 0.199
C86.5 Angioimmunoblastic T-cell lymphoma
0.004 0.797 0.199
C86.4 Blastic NK-cell lymphoma
0.004 0.797 0.199
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.004 0.797 0.199
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.004 0.797 0.199
C86.1 Hepatosplenic T-cell lymphoma
0.004 0.797 0.199
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.004 0.797 0.199
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.004 0.797 0.199
C96.8 Histiocytic sarcoma
0.004 0.797 0.199
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.004 0.797 0.199
C96.6 Unifocal Langerhans-cell histiocytosis
0.004 0.797 0.199
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.004 0.797 0.199
C96.4 Sarcoma of dendritic cells (accessory cells)
0.004 0.797 0.199
C96.3 True histiocytic lymphoma
0.004 0.797 0.199
C96.2 Malignant mast cell tumour
0.004 0.797 0.199
C96.1 Malignant histiocytosis
0.004 0.797 0.199
C96.0 Letterer-Siwe disease
0.004 0.797 0.199
E58 Dietary calcium deficiency
0.000 0.798 0.202
C81.7 Other Hodgkin's disease
0.003 0.799 0.199
E24.8 Other Cushing's syndrome
0.000 0.799 0.201
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.799 0.201
E24.3 Ectopic ACTH syndrome
0.000 0.799 0.201
E24.1 Nelson's syndrome
0.000 0.799 0.201
E24.0 Pituitary-dependent Cushing's disease
0.000 0.799 0.201
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.799 0.200
E23.1 Drug-induced hypopituitarism
0.000 0.799 0.200
C84.0 Mycosis fungoides
0.003 0.800 0.197
C84.9 Mature T/NK-cell lymphoma, unspecified
0.003 0.800 0.197
C84.8 Cutaneous T-cell lymphoma, unspecified
0.003 0.800 0.197
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.003 0.800 0.197
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.003 0.800 0.197
C84.3 Lymphoepithelioid lymphoma
0.003 0.800 0.197
C84.2 T-zone lymphoma
0.003 0.800 0.197
C84.1 Sezary's diease
0.003 0.800 0.197
E61 Deficiency of other nutrient elements
0.000 0.800 0.199
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.804 0.196
C82.1 Mixed small cleaved and large cell, follicular
0.002 0.804 0.194
C81.0 Lymphocytic predominance
0.003 0.804 0.193
E51 Thiamine deficiency
0.000 0.804 0.195
E23.6 Other disorders of pituitary gland
0.000 0.806 0.194
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.808 0.192
E29 Testicular dysfunction
0.000 0.808 0.191
C91.9 Lymphoid leukaemia, unspecified
0.002 0.810 0.188
C84.4 Peripheral T-cell lymphoma
0.003 0.811 0.186
E23.0 Hypopituitarism
0.000 0.812 0.188
E06.3 Autoimmune thyroiditis
0.000 0.813 0.186
C94.7 Other specified leukaemias
0.004 0.814 0.181
C94.5 Acute myelofibrosis
0.004 0.814 0.181
C94.4 Acute panmyelosis
0.004 0.814 0.181
C94.3 Mast cell leukaemia
0.004 0.814 0.181
C94.2 Acute megakaryoblastic leukaemia
0.004 0.814 0.181
C94.1 Chronic erythraemia
0.004 0.814 0.181
C94.0 Acute erythraemia and erythroleukaemia
0.004 0.814 0.181
E21.4 Other specified disorders of parathyroid gland
0.000 0.815 0.185
E21.2 Other hyperparathyroidism
0.000 0.815 0.185
C95 Leukaemia of unspecified cell type
0.007 0.816 0.177
E28.3 Primary ovarian failure
0.000 0.816 0.183
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.818 0.182
E25.9 Adrenogenital disorder, unspecified
0.000 0.820 0.179
E25.8 Other adrenogenital disorders
0.000 0.820 0.179
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.820 0.179
E30.9 Disorder of puberty, unspecified
0.000 0.820 0.179
E30.8 Other disorders of puberty
0.000 0.820 0.179
E30.1 Precocious puberty
0.000 0.820 0.179
E30.0 Delayed puberty
0.000 0.820 0.179
E31.9 Polyglandular dysfunction, unspecified
0.000 0.820 0.179
E31.8 Other polyglandular dysfunction
0.000 0.820 0.179
E31.1 Polyglandular hyperfunction
0.000 0.820 0.179
E31.0 Autoimmune polyglandular failure
0.000 0.820 0.179
E32.9 Disease of thymus, unspecified
0.000 0.820 0.179
E32.8 Other diseases of thymus
0.000 0.820 0.179
E32.1 Abscess of thymus
0.000 0.820 0.179
E32.0 Persistent hyperplasia of thymus
0.000 0.820 0.179
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.820 0.179
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.820 0.179
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.820 0.179
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.004 0.826 0.169
E06.9 Thyroiditis, unspecified
0.001 0.827 0.172
C93.9 Monocytic leukaemia, unspecified
0.004 0.827 0.168
C93.7 Other monocytic leukaemia
0.004 0.827 0.168
C93.3 Juvenile myelomonocytic leukaemia
0.004 0.827 0.168
C93.2 Subacute monocytic leukaemia
0.004 0.827 0.168
C93.0 Acute monocytic leukaemia
0.004 0.827 0.168
E65 Localised adiposity
0.000 0.829 0.171
E22 Hyperfunction of pituitary gland
0.000 0.830 0.170
E67.8 Other specified hyperalimentation
0.000 0.831 0.168
E67.3 Hypervitaminosis D
0.000 0.831 0.168
E67.2 Megavitamin-B6 syndrome
0.000 0.831 0.168
E67.1 Hypercarotenaemia
0.000 0.831 0.168
E67.0 Hypervitaminosis A
0.000 0.831 0.168
E26.9 Hyperaldosteronism, unspecified
0.000 0.834 0.165
E26.8 Other hyperaldosteronism
0.000 0.834 0.165
E26.1 Secondary hyperaldosteronism
0.000 0.834 0.165
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.005 0.838 0.157
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.004 0.838 0.158
C83.0 Small cell (diffuse)
0.005 0.838 0.157
C88.9 Malignant immunoproliferative disease, unspecified
0.005 0.841 0.155
C88.7 Other malignant immunoproliferative diseases
0.005 0.841 0.155
C88.3 Immunoproliferative small intestinal disease
0.005 0.841 0.155
C88.2 Gamma heavy chain disease
0.005 0.841 0.155
C88.1 Alpha heavy chain disease
0.005 0.841 0.155
C91.5 Adult T-cell leukaemia
0.003 0.845 0.151
C92 Myeloid leukaemia
0.006 0.846 0.148
C91.8 Mature B-cell leukaemia Burkitt-type
0.003 0.846 0.150
C91.7 Other lymphoid leukaemia
0.003 0.846 0.150
C91.6 Prolymphocytic leukaemia of T-cell type
0.003 0.846 0.150
C91.3 Prolymphocytic leukaemia
0.003 0.846 0.150
C91.2 Subacute lymphocytic leukaemia
0.003 0.846 0.150
C81.1 Nodular sclerosis
0.003 0.848 0.148
E50.9 Vitamin A deficiency, unspecified
0.000 0.850 0.150
E50.8 Other manifestations of vitamin A deficiency
0.000 0.850 0.150
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.850 0.150
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.850 0.150
E50.5 Vitamin A deficiency with night blindness
0.000 0.850 0.150
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.850 0.150
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.850 0.150
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.850 0.150
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.850 0.150
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.850 0.150
E63.9 Nutritional deficiency, unspecified
0.000 0.850 0.150
E63.8 Other specified nutritional deficiencies
0.000 0.850 0.150
E63.1 Imbalance of constituents of food intake
0.000 0.850 0.150
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.850 0.150

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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