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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-28452186
log Bayes Factor = 28.6349
Chromosome 6   position 31,321,882  (GRCh37) Explore Affx-28452186 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.002 0.998
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
E65-E68 Obesity and other hyperalimentation
0.000 0.004 0.996
E66 Obesity
0.000 0.007 0.993
E66.8 Other obesity
0.000 0.008 0.992
J45.9 Asthma, unspecified
0.992 0.008 0.000
L40.0 Psoriasis vulgaris
0.000 0.045 0.955
E10.2 With renal complications
0.000 0.056 0.944
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.061 0.939
E50-E64 Other nutritional deficiencies
0.000 0.076 0.924
E06 Thyroiditis
0.000 0.082 0.918
E05.9 Thyrotoxicosis, unspecified
0.000 0.115 0.885
L40-L45 Papulosquamous disorders
0.000 0.127 0.873
E40-E46 Malnutrition
0.000 0.130 0.870
E10.4 With neurological complications
0.000 0.136 0.864
G37 Other demyelinating diseases of central nervous system
0.000 0.144 0.856
E53 Deficiency of other B group vitamins
0.000 0.156 0.844
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.157 0.843
M07.3 Other psoriatic arthropathies
0.000 0.159 0.841
E10.1 With ketoacidosis
0.000 0.163 0.837
E66.0 Obesity due to excess calories
0.000 0.164 0.836
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.167 0.833
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.167 0.833
D86 Sarcoidosis
0.000 0.173 0.827
D80-D89 Certain disorders involving the immune mechanism
0.000 0.175 0.825
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.176 0.824
E10.5 With peripheral circulatory complications
0.000 0.177 0.823
D60-D64 Aplastic and other anaemias
0.000 0.178 0.822
E11 Non-insulin-dependent diabetes mellitus
0.000 0.182 0.818
D61 Other aplastic anaemias
0.000 0.183 0.817
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.183 0.817
D61.9 Aplastic anaemia, unspecified
0.000 0.185 0.815
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.190 0.810
D86.9 Sarcoidosis, unspecified
0.000 0.193 0.807
# Top node
0.000 0.198 0.802
M07 Psoriatic and enteropathic arthropathies
0.000 0.199 0.801
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.201 0.799
Chapter VI Diseases of the nervous system
0.000 0.202 0.798
E06.3 Autoimmune thyroiditis
0.000 0.203 0.797
E06.9 Thyroiditis, unspecified
0.000 0.204 0.796
E53.8 Deficiency of other specified B group vitamins
0.000 0.213 0.787
N47 Redundant prepuce, phimosis and paraphimosis
0.783 0.217 0.000
D86.0 Sarcoidosis of lung
0.000 0.217 0.783
G40-G47 Episodic and paroxysmal disorders
0.000 0.219 0.781
E46 Unspecified protein-energy malnutrition
0.000 0.223 0.777
K90 Intestinal malabsorption
0.000 0.225 0.775
D75 Other diseases of blood and blood-forming organs
0.000 0.225 0.775
G47.9 Sleep disorder, unspecified
0.000 0.226 0.774
M05-M14 Inflammatory polyarthropathies
0.000 0.228 0.772
G47 Sleep disorders
0.000 0.229 0.771
E10.6 With other specified complications
0.000 0.233 0.767
L40.8 Other psoriasis
0.000 0.233 0.767
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.234 0.766
E10.8 With unspecified complications
0.000 0.235 0.765
E55 Vitamin D deficiency
0.000 0.245 0.755
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.249 0.751
G40 Epilepsy
0.000 0.252 0.748
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.265 0.734
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.270 0.730
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.000 0.274 0.726
D86.1 Sarcoidosis of lymph nodes
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E65 Localised adiposity
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E67 Other hyperalimentation
0.000 0.286 0.714
E68 Sequelae of hyperalimentation
0.000 0.286 0.714
N48.6 Balanitis xerotica obliterans
0.714 0.286 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.288 0.712
E66.1 Drug-induced obesity
0.000 0.288 0.712
M20-M25 Other joint disorders
0.000 0.289 0.711
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.291 0.709
L89 Decubitus ulcer
0.000 0.292 0.708
D72 Other disorders of white blood cells
0.000 0.292 0.708
N48 Other disorders of penis
0.705 0.295 0.000
E11.4 With neurological complications
0.000 0.301 0.699
G40.8 Other epilepsy
0.000 0.309 0.691
N40-N51 Diseases of male genital organs
0.687 0.313 0.000
N48.0 Leukoplakia of penis
0.679 0.321 0.000
M35 Other systemic involvement of connective tissue
0.000 0.326 0.674
G36 Other acute disseminated demyelination
0.000 0.327 0.673
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.328 0.672
E11.5 With peripheral circulatory complications
0.000 0.332 0.668
D73 Diseases of spleen
0.000 0.336 0.664
E05.8 Other thyrotoxicosis
0.000 0.336 0.664
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.337 0.663
E63 Other nutritional deficiencies
0.000 0.337 0.663
E56 Other vitamin deficiencies
0.000 0.337 0.663
E51 Thiamine deficiency
0.000 0.337 0.663
E50 Vitamin A deficiency
0.000 0.337 0.663
E60 Dietary zinc deficiency
0.000 0.337 0.663
E59 Dietary selenium deficiency
0.000 0.337 0.663
E58 Dietary calcium deficiency
0.000 0.337 0.663
E54 Ascorbic acid deficiency
0.000 0.337 0.663
E52 Niacin deficiency [pellagra]
0.000 0.337 0.663
M15-M19 Arthrosis
0.000 0.338 0.662
D86.8 Sarcoidosis of other and combined sites
0.000 0.339 0.661
M17 Gonarthrosis [arthrosis of knee]
0.000 0.340 0.660
E06.5 Other chronic thyroiditis
0.000 0.342 0.658
E06.4 Drug-induced thyroiditis
0.000 0.342 0.658
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.342 0.658
E06.1 Subacute thyroiditis
0.000 0.342 0.658
E06.0 Acute thyroiditis
0.000 0.342 0.658
L89.9 Decubitus ulcer and pressure area, unspecified
0.000 0.343 0.657
E61 Deficiency of other nutrient elements
0.000 0.348 0.652
M35.0 Sicca syndrome [Sjogren]
0.000 0.350 0.650
M17.1 Other primary gonarthrosis
0.000 0.352 0.648
E11.6 With other specified complications
0.000 0.354 0.646
M17.0 Primary gonarthrosis, bilateral
0.000 0.354 0.646
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.358 0.642
D64 Other anaemias
0.000 0.361 0.639
M25 Other joint disorders, not elsewhere classified
0.000 0.361 0.639
D72.8 Other specified disorders of white blood cells
0.000 0.361 0.639
E11.2 With renal complications
0.000 0.364 0.636
E11.3 With ophthalmic complications
0.000 0.367 0.633
E55.9 Vitamin D deficiency, unspecified
0.000 0.367 0.633
E11.8 With unspecified complications
0.000 0.373 0.627
L44 Other papulosquamous disorders
0.000 0.374 0.626
L41 Parapsoriasis
0.000 0.374 0.626
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.374 0.626
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.376 0.624
E45 Retarded development following protein-energy malnutrition
0.000 0.376 0.624
E43 Unspecified severe protein-energy malnutrition
0.000 0.376 0.624
E42 Marasmic kwashiorkor
0.000 0.376 0.624
E41 Nutritional marasmus
0.000 0.376 0.624
E40 Kwashiorkor
0.000 0.376 0.624
D75.1 Secondary polycythaemia
0.000 0.378 0.622
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.378 0.622
L43 Lichen planus
0.000 0.378 0.622
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.379 0.621
E10.0 With coma
0.000 0.379 0.621
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.382 0.618
L10-L14 Bullous disorders
0.000 0.383 0.617
L89.0 Stage I decubitus ulcer and pressure area
0.000 0.384 0.616
L81 Other disorders of pigmentation
0.000 0.385 0.615
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.386 0.613
G37.5 Concentric sclerosis [Balo]
0.000 0.386 0.613
G37.4 Subacute necrotising myelitis
0.000 0.386 0.613
G37.2 Central pontine myelinolysis
0.000 0.386 0.613
G37.1 Central demyelination of corpus callosum
0.000 0.386 0.613
G37.0 Diffuse sclerosis
0.000 0.386 0.613
D63.0 Anaemia in neoplastic disease
0.000 0.387 0.613
D61.1 Drug-induced aplastic anaemia
0.000 0.390 0.610
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.393 0.607
L89.1 Stage II decubitus ulcer
0.000 0.393 0.607
E53.1 Pyridoxine deficiency
0.000 0.395 0.605
E53.0 Riboflavin deficiency
0.000 0.395 0.605
M14 Arthropathies in other diseases classified elsewhere
0.000 0.396 0.604
E53.9 Vitamin B deficiency, unspecified
0.000 0.397 0.603
M07.38 Other psoriatic arthropathies (Other)
0.000 0.397 0.603
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.397 0.603
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.397 0.603
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.397 0.603
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.397 0.603
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.397 0.603
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.397 0.603
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.397 0.603
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.400 0.600
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.401 0.599
E14 Unspecified diabetes mellitus
0.000 0.404 0.596
D86.3 Sarcoidosis of skin
0.000 0.407 0.593
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.407 0.593
D82 Immunodeficiency associated with other major defects
0.000 0.408 0.591
D81 Combined immunodeficiencies
0.000 0.408 0.591
L83 Acanthosis nigricans
0.000 0.409 0.591
M34 Systemic sclerosis
0.000 0.412 0.588
E11.7 With multiple complications
0.000 0.414 0.586
D61.8 Other specified aplastic anaemias
0.000 0.414 0.586
D61.3 Idiopathic aplastic anaemia
0.000 0.414 0.586
D61.2 Aplastic anaemia due to other external agents
0.000 0.414 0.586
E10.9 Without complications
0.000 0.415 0.585
D74 Methaemoglobinaemia
0.000 0.419 0.581
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.419 0.581
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.419 0.581
E13 Other specified diabetes mellitus
0.000 0.420 0.580
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.420 0.580
M13 Other arthritis
0.000 0.423 0.577
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.425 0.575
M07.6 Other enteropathic arthropathies
0.000 0.426 0.574
M07.5 Arthropathy in ulcerative colitis
0.000 0.426 0.574
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.426 0.574
M07.2 Psoriatic spondylitis
0.000 0.426 0.574
M07.1 Arthritis mutilans
0.000 0.426 0.574
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.426 0.574
E16 Other disorders of pancreatic internal secretion
0.000 0.428 0.572
M25.9 Joint disorder, unspecified
0.000 0.428 0.572
L20-L30 Dermatitis and eczema
0.000 0.429 0.571
E11.1 With ketoacidosis
0.000 0.430 0.570
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.000 0.431 0.569
L89.2 Stage III decubitus ulcer
0.000 0.433 0.567
M60-M63 Disorders of muscles
0.000 0.434 0.566
K90-K93 Other diseases of the digestive system
0.000 0.436 0.564
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.437 0.563
L81.4 Other melanin hyperpigmentation
0.000 0.438 0.562
G47.1 Disorders of excessive somnolence [hypersomnias]
0.000 0.438 0.561
M17.5 Other secondary gonarthrosis
0.000 0.439 0.561
M25.4 Effusion of joint
0.000 0.440 0.560
D83 Common variable immunodeficiency
0.000 0.442 0.557
D61.0 Constitutional aplastic anaemia
0.000 0.443 0.556
G41 Status epilepticus
0.000 0.444 0.556
K90.3 Pancreatic steatorrhoea
0.000 0.444 0.556
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.444 0.556
K90.1 Tropical sprue
0.000 0.444 0.556
D75.0 Familial erythrocytosis
0.000 0.444 0.556
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.446 0.554
M08 Juvenile arthritis
0.000 0.446 0.554
G47.2 Disorders of the sleep-wake schedule
0.000 0.447 0.553
L85 Other epidermal thickening
0.000 0.449 0.551
M32 Systemic lupus erythematosus
0.000 0.449 0.551
K90.9 Intestinal malabsorption, unspecified
0.000 0.449 0.551
M33 Dermatopolymyositis
0.000 0.452 0.548
K90.8 Other intestinal malabsorption
0.000 0.453 0.547
L89.3 Stage IV decubitus ulcer
0.000 0.453 0.547
L80 Vitiligo
0.000 0.456 0.544
M21 Other acquired deformities of limbs
0.000 0.456 0.544
M45-M49 Spondylopathies
0.000 0.457 0.543
M00-M03 Infectious arthropathies
0.000 0.457 0.543
L92.0 Granuloma annulare
0.000 0.458 0.542
E55.0 Rickets, active
0.000 0.459 0.541
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.460 0.540
G45 Transient cerebral ischaemic attacks and related syndromes
0.000 0.461 0.539
D73.8 Other diseases of spleen
0.000 0.461 0.539
E15 Nondiabetic hypoglycaemic coma
0.000 0.462 0.538
G40.4 Other generalised epilepsy and epileptic syndromes
0.000 0.464 0.536
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.000 0.464 0.536
M45 Ankylosing spondylitis
0.000 0.464 0.536
G46 Vascular syndromes of brain in cerebrovascular diseases
0.000 0.464 0.536
D55-D59 Haemolytic anaemias
0.000 0.467 0.533
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.467 0.533
M91-M94 Chondropathies
0.000 0.469 0.531
N48.5 Ulcer of penis
0.530 0.469 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.530 0.470 0.000
M11 Other crystal arthropathies
0.000 0.471 0.529
M80-M85 Disorders of bone density and structure
0.000 0.472 0.528
L94 Other localised connective tissue disorders
0.000 0.472 0.528
D75.2 Essential thrombocytosis
0.000 0.473 0.527
M12 Other specific arthropathies
0.000 0.473 0.527
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.527 0.473 0.000
D73.0 Hyposplenism
0.000 0.474 0.526
M35.7 Hypermobility syndrome
0.000 0.474 0.526
D50-D53 Nutritional anaemias
0.000 0.474 0.525
M35.3 Polymyalgia rheumatica
0.000 0.475 0.525
M06 Other rheumatoid arthritis
0.000 0.477 0.523
L28 Lichen simplex chronicus and prurigo
0.000 0.480 0.520
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.481 0.519
M24 Other specific joint derangements
0.000 0.483 0.517
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.486 0.514
L87 Transepidermal elimination disorders
0.000 0.486 0.514
L88 Pyoderma gangrenosum
0.000 0.486 0.514
L86 Keratoderma in diseases classified elsewhere
0.000 0.486 0.514
G47.8 Other sleep disorders
0.000 0.486 0.514
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.486 0.513
E14.3 With ophthalmic complications
0.000 0.486 0.514
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.487 0.513
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
M25.0 Haemarthrosis
0.000 0.487 0.513
E67.8 Other specified hyperalimentation
0.000 0.488 0.512
E67.3 Hypervitaminosis D
0.000 0.488 0.512
E67.2 Megavitamin-B6 syndrome
0.000 0.488 0.512
E67.1 Hypercarotenaemia
0.000 0.488 0.512
E67.0 Hypervitaminosis A
0.000 0.488 0.512
D84 Other immunodeficiencies
0.000 0.489 0.511
N48.2 Other inflammatory disorders of penis
0.511 0.489 0.000
M30 Polyarteritis nodosa and related conditions
0.000 0.490 0.510
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.490 0.509
M14.6 Neuropathic arthropathy
0.000 0.491 0.509
M80 Osteoporosis with pathological fracture
0.000 0.492 0.508
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.492 0.508
N48.8 Other specified disorders of penis
0.508 0.492 0.000
D72.9 Disorder of white blood cells, unspecified
0.000 0.493 0.507
D72.0 Genetic anomalies of leukocytes
0.000 0.493 0.507
L93 Lupus erythematosus
0.000 0.493 0.507
D64.9 Anaemia, unspecified
0.000 0.493 0.507
N48.3 Priapism
0.506 0.494 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.000 0.499 0.501
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.499 0.500
M25.46 Effusion of joint (Lower leg)
0.000 0.503 0.497
M25.7 Osteophyte
0.000 0.505 0.495
D72.1 Eosinophilia
0.000 0.505 0.495
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.507 0.493
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.507 0.493
G40.5 Special epileptic syndromes
0.000 0.508 0.492
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.508 0.492
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.509 0.491
M25.96 Joint disorder, unspecified (Lower leg)
0.000 0.509 0.491
M25.5 Pain in joint
0.000 0.511 0.489
G47.4 Narcolepsy and cataplexy
0.000 0.515 0.484
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.516 0.483
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.516 0.483
M35.5 Multifocal fibrosclerosis
0.000 0.516 0.483
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.516 0.483
M25.97 Joint disorder, unspecified (Ankle and foot)
0.000 0.517 0.483
G36.9 Acute disseminated demyelination, unspecified
0.000 0.517 0.483
G36.8 Other specified acute disseminated demyelination
0.000 0.517 0.483
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.517 0.483
G36.0 Neuromyelitis optica [Devic]
0.000 0.517 0.483
E11.0 With coma
0.000 0.518 0.482
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.518 0.482
L58 Radiodermatitis
0.000 0.518 0.482
L55 Sunburn
0.000 0.518 0.482
L28.0 Lichen simplex chronicus
0.000 0.519 0.481
L42 Pityriasis rosea
0.000 0.519 0.480
L43.8 Other lichen planus
0.000 0.520 0.480
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.520 0.480
M34.1 CR(E)ST syndrome
0.000 0.521 0.479
D73.5 Infarction of spleen
0.000 0.523 0.477
D73.9 Disease of spleen, unspecified
0.000 0.523 0.476
D73.4 Cyst of spleen
0.000 0.523 0.476
D73.3 Abscess of spleen
0.000 0.523 0.476
D73.2 Chronic congestive splenomegaly
0.000 0.523 0.476
M22 Disorders of patella
0.000 0.524 0.476
E50.9 Vitamin A deficiency, unspecified
0.000 0.525 0.475
E50.8 Other manifestations of vitamin A deficiency
0.000 0.525 0.475
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.525 0.475
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.525 0.475
E50.5 Vitamin A deficiency with night blindness
0.000 0.525 0.475
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.525 0.475
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.525 0.475
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.525 0.475
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.525 0.475
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.525 0.475
E51.9 Thiamine deficiency, unspecified
0.000 0.525 0.475
E51.8 Other manifestations of thiamine deficiency
0.000 0.525 0.475
E51.2 Wernicke's encephalopathy
0.000 0.525 0.475
E51.1 Beriberi
0.000 0.525 0.475
E56.9 Vitamin deficiency, unspecified
0.000 0.525 0.475
E56.8 Deficiency of other vitamins
0.000 0.525 0.475
E56.1 Deficiency of vitamin K
0.000 0.525 0.475
E56.0 Deficiency of vitamin E
0.000 0.525 0.475
E63.9 Nutritional deficiency, unspecified
0.000 0.525 0.475
E63.8 Other specified nutritional deficiencies
0.000 0.525 0.475
E63.1 Imbalance of constituents of food intake
0.000 0.525 0.475
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.525 0.475
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.525 0.475
E64.8 Sequelae of other nutritional deficiencies
0.000 0.525 0.475
E64.3 Sequelae of rickets
0.000 0.525 0.475
E64.2 Sequelae of vitamin C deficiency
0.000 0.525 0.475
E64.1 Sequelae of vitamin A deficiency
0.000 0.525 0.475
E64.0 Sequelae of protein-energy malnutrition
0.000 0.525 0.475
M25.45 Effusion of joint (Pelvic region and thigh)
0.000 0.525 0.475
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.525 0.475
M21.4 Flat foot [pes planus] (acquired)
0.000 0.526 0.474
M17.2 Posttraumatic gonarthrosis, bilateral
0.000 0.526 0.473
N48.9 Disorder of penis, unspecified
0.471 0.529 0.000
E07 Other disorders of thyroid
0.000 0.529 0.470
M21.0 Valgus deformity, not elsewhere classified
0.000 0.530 0.470
E61.9 Deficiency of nutrient element, unspecified
0.000 0.532 0.468
E61.8 Deficiency of other specified nutrient elements
0.000 0.532 0.468
E61.7 Deficiency of multiple nutrient elements
0.000 0.532 0.468
E61.6 Vanadium deficiency
0.000 0.532 0.468
E61.5 Molybdenum deficiency
0.000 0.532 0.468
E61.4 Chromium deficiency
0.000 0.532 0.468
E61.3 Manganese deficiency
0.000 0.532 0.468
E61.0 Copper deficiency
0.000 0.532 0.468
L12 Pemphigoid
0.000 0.533 0.467
Chapter XI Diseases of the digestive system
0.000 0.535 0.465
E61.1 Iron deficiency
0.000 0.536 0.464
L21 Seborrhoeic dermatitis
0.000 0.537 0.463
M35.2 Behcet's disease
0.000 0.537 0.463
L81.8 Other specified disorders of pigmentation
0.000 0.537 0.463
E61.2 Magnesium deficiency
0.000 0.538 0.461
D80 Immunodeficiency with predominantly antibody defects
0.000 0.539 0.461
L92.2 Granuloma faciale [eosinophilic granuloma of skin]
0.000 0.540 0.460
L92.1 Necrobiosis lipoidica, not elsewhere classified
0.000 0.540 0.460
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.540 0.460
D64.8 Other specified anaemias
0.000 0.540 0.460
M05 Seropositive rheumatoid arthritis
0.000 0.541 0.459
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.542 0.458
D64.4 Congenital dyserythropoietic anaemia
0.000 0.542 0.458
D64.3 Other sideroblastic anaemias
0.000 0.542 0.458
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.542 0.458
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.542 0.458
D64.0 Hereditary sideroblastic anaemia
0.000 0.542 0.458
M25.2 Flail joint
0.000 0.542 0.458
M25.1 Fistula of joint
0.000 0.542 0.458
M35.1 Other overlap syndromes
0.000 0.542 0.458
G40.7 Petit mal, unspecified, without grand mal seizures
0.000 0.543 0.457
N44 Torsion of testis
0.456 0.543 0.000
N45 Orchitis and epididymitis
0.457 0.543 0.000
N48.1 Balanoposthitis
0.456 0.544 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.544 0.456
M06.0 Seronegative rheumatoid arthritis
0.000 0.545 0.455
M31 Other necrotising vasculopathies
0.000 0.546 0.454
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.546 0.454
D73.1 Hypersplenism
0.000 0.548 0.452
N46 Male infertility
0.450 0.550 0.000
N43 Hydrocele and spermatocele
0.449 0.551 0.000
L41.9 Parapsoriasis, unspecified
0.000 0.551 0.449
L41.8 Other parapsoriasis
0.000 0.551 0.449
L41.5 Retiform parapsoriasis
0.000 0.551 0.449
L41.4 Large plaque parapsoriasis
0.000 0.551 0.449
L41.3 Small plaque parapsoriasis
0.000 0.551 0.449
L41.2 Lymphomatoid papulosis
0.000 0.551 0.449
L41.1 Pityriasis lichenoides chronica
0.000 0.551 0.449
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.551 0.449
L44.9 Papulosquamous disorder, unspecified
0.000 0.551 0.449
L44.8 Other specified papulosquamous disorders
0.000 0.551 0.449
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.551 0.449
L44.3 Lichen ruber moniliformis
0.000 0.551 0.449
L44.2 Lichen striatus
0.000 0.551 0.449
L44.1 Lichen nitidus
0.000 0.551 0.449
L44.0 Pityriasis rubra pilaris
0.000 0.551 0.449
L13 Other bullous disorders
0.000 0.551 0.449
D76.3 Other histiocytosis syndromes
0.000 0.551 0.449
G45.4 Transient global amnesia
0.000 0.551 0.449
M24.2 Disorder of ligament
0.000 0.552 0.448
L94.0 Localised scleroderma [morphea]
0.000 0.552 0.448
E44.1 Mild protein-energy malnutrition
0.000 0.553 0.447
E44.0 Moderate protein-energy malnutrition
0.000 0.553 0.447
L43.3 Subacute (active) lichen planus
0.000 0.554 0.446
L43.2 Lichenoid drug reaction
0.000 0.554 0.446
L43.1 Bullous lichen planus
0.000 0.554 0.446
L43.0 Hypertrophic lichen planus
0.000 0.554 0.446
L25 Unspecified contact dermatitis
0.000 0.556 0.444
L11 Other acantholytic disorders
0.000 0.558 0.442
L10 Pemphigus
0.000 0.558 0.442
L14 Bullous disorders in diseases classified elsewhere
0.000 0.558 0.442
M17.3 Other posttraumatic gonarthrosis
0.000 0.558 0.442
M34.9 Systemic sclerosis, unspecified
0.000 0.558 0.442
L81.7 Pigmented purpuric dermatosis
0.000 0.559 0.441
L81.6 Other disorders of diminished melanin formation
0.000 0.559 0.441
L81.5 Leukoderma, not elsewhere classified
0.000 0.559 0.441
L81.3 Cafe au lait spots
0.000 0.559 0.441
L81.1 Chloasma
0.000 0.559 0.441
L81.0 Postinflammatory hyperpigmentation
0.000 0.559 0.441
M25.91 Joint disorder, unspecified (Shoulder region)
0.000 0.560 0.440
M13.99 Arthritis, unspecified (Site unspecified)
0.000 0.561 0.439
M25.77 Osteophyte (Ankle and foot)
0.000 0.561 0.439
E14.4 With neurological complications
0.000 0.562 0.438
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.564 0.436
M25.43 Effusion of joint (Forearm)
0.000 0.564 0.436
M13.9 Arthritis, unspecified
0.000 0.564 0.436
E16.2 Hypoglycaemia, unspecified
0.000 0.565 0.435
M34.8 Other forms of systemic sclerosis
0.000 0.566 0.434
N42 Other disorders of prostate
0.434 0.566 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.567 0.433
M14.4 Arthropathy in amyloidosis
0.000 0.567 0.433
M14.3 Lipoid dermatoarthritis
0.000 0.567 0.433
M14.2 Diabetic arthropathy
0.000 0.567 0.433
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.567 0.433
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.567 0.433
M25.76 Osteophyte (Lower leg)
0.000 0.567 0.433
M24.0 Loose body in joint
0.000 0.568 0.432
N49.8 Inflammatory disorders of other specified male genital organs
0.430 0.570 0.000
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.570 0.430
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.570 0.430
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.570 0.430
M13.8 Other specified arthritis
0.000 0.571 0.429
G70-G73 Diseases of myoneural junction and muscle
0.000 0.572 0.428
E14.8 With unspecified complications
0.000 0.572 0.428
E14.7 With multiple complications
0.000 0.572 0.428
E14.6 With other specified complications
0.000 0.572 0.428
E14.0 With coma
0.000 0.572 0.428
G41.9 Status epilepticus, unspecified
0.000 0.573 0.427
M15 Polyarthrosis
0.000 0.573 0.427
L85.8 Other specified epidermal thickening
0.000 0.574 0.426
M25.94 Joint disorder, unspecified (Hand)
0.000 0.574 0.425
D81.9 Combined immunodeficiency, unspecified
0.000 0.576 0.424
D81.8 Other combined immunodeficiencies
0.000 0.576 0.424
D81.7 Major histocompatibility complex class II deficiency
0.000 0.576 0.424
D81.6 Major histocompatibility complex class I deficiency
0.000 0.576 0.424
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.576 0.424

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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