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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-28453750
log Bayes Factor = 103.934
Chromosome 6   position 31,340,491  (GRCh37) Explore Affx-28453750 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
M45 Ankylosing spondylitis
0.999 0.001 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.999 0.001 0.000
E10.1 With ketoacidosis
0.000 0.003 0.997
E14.9 Without complications
0.000 0.003 0.997
G35 Multiple sclerosis
0.994 0.006 0.000
K51.4 Pseudopolyposis of colon
0.993 0.007 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.008 0.992
M06.9 Rheumatoid arthritis, unspecified
0.000 0.008 0.992
K51.2 Ulcerative (chronic) proctitis
0.988 0.012 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.016 0.984
E20-E35 Disorders of other endocrine glands
0.000 0.016 0.984
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.025 0.975
E10.4 With neurological complications
0.000 0.027 0.973
K51.3 Ulcerative (chronic) rectosigmoiditis
0.966 0.034 0.000
E27 Other disorders of adrenal gland
0.000 0.038 0.962
E00-E07 Disorders of thyroid gland
0.000 0.040 0.960
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.040 0.960
E05.9 Thyrotoxicosis, unspecified
0.000 0.045 0.955
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.052 0.948
E11.1 With ketoacidosis
0.000 0.053 0.947
E11.3 With ophthalmic complications
0.000 0.066 0.934
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.067 0.933
E10.0 With coma
0.000 0.074 0.926
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.079 0.921
E11.0 With coma
0.000 0.089 0.911
E27.1 Primary adrenocortical insufficiency
0.000 0.097 0.903
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.098 0.902
E10.8 With unspecified complications
0.000 0.100 0.900
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.111 0.889
E14.1 With ketoacidosis
0.000 0.114 0.886
K51.5 Mucosal proctocolitis
0.882 0.118 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.122 0.878
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.131 0.869
E10.6 With other specified complications
0.000 0.140 0.860
E23 Hypofunction and other disorders of pituitary gland
0.000 0.143 0.857
M45.X2 Ankylosing spondylitis (Cervical region)
0.837 0.163 0.000
E11.5 With peripheral circulatory complications
0.000 0.167 0.833
K51.8 Other ulcerative colitis
0.833 0.167 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.175 0.825
E14.6 With other specified complications
0.000 0.180 0.820
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.810 0.190 0.000
E22 Hyperfunction of pituitary gland
0.000 0.191 0.809
E10.2 With renal complications
0.000 0.196 0.804
E24 Cushing's syndrome
0.000 0.198 0.802
E14.3 With ophthalmic complications
0.000 0.205 0.795
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.206 0.794
E23.2 Diabetes insipidus
0.000 0.207 0.793
J45 Asthma
0.000 0.213 0.787
M45.X6 Ankylosing spondylitis (Lumbar region)
0.784 0.216 0.000
E16.1 Other hypoglycaemia
0.000 0.232 0.768
G35-G37 Demyelinating diseases of the central nervous system
0.768 0.232 0.000
E14.2 Withrenal complications
0.000 0.232 0.768
E13 Other specified diabetes mellitus
0.000 0.234 0.766
E10.5 With peripheral circulatory complications
0.000 0.242 0.758
E05.8 Other thyrotoxicosis
0.000 0.246 0.754
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.263 0.737
E25 Adrenogenital disorders
0.000 0.273 0.727
E40-E46 Malnutrition
0.000 0.275 0.725
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.280 0.720
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.716
E14.0 With coma
0.000 0.283 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.716
E16.3 Increased secretion of glucagon
0.000 0.283 0.716
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E14.8 With unspecified complications
0.000 0.286 0.714
E28 Ovarian dysfunction
0.000 0.287 0.713
G37 Other demyelinating diseases of central nervous system
0.712 0.288 0.000
E11.7 With multiple complications
0.000 0.289 0.711
E34 Other endocrine disorders
0.000 0.293 0.707
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.294 0.706
E32 Diseases of thymus
0.000 0.294 0.706
E30 Disorders of puberty, not elsewhere classified
0.000 0.294 0.706
E26 Hyperaldosteronism
0.000 0.294 0.706
E10.7 With multiple complications
0.000 0.297 0.702
E24.0 Pituitary-dependent Cushing's disease
0.000 0.306 0.694
J45.0 Predominantly allergic asthma
0.000 0.306 0.694
E14.5 With peripheral circulatory complications
0.000 0.310 0.690
E27.5 Adrenomedullary hyperfunction
0.000 0.310 0.690
E27.0 Other adrenocortical overactivity
0.000 0.310 0.690
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.312 0.688
E00 Congenital iodine-deficiency syndrome
0.000 0.312 0.688
E05.5 Thyroid crisis or storm
0.000 0.312 0.688
E05.4 Thyrotoxicosis factitia
0.000 0.312 0.688
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.312 0.688
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.312 0.688
K51.0 Ulcerative (chronic) enterocolitis
0.686 0.314 0.000
E31 Polyglandular dysfunction
0.000 0.316 0.684
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.325 0.675
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.325 0.675
E07 Other disorders of thyroid
0.000 0.326 0.674
E23.7 Disorder of pituitary gland, unspecified
0.000 0.330 0.670
G37.9 Demyelinating disease of central nervous system, unspecified
0.670 0.330 0.000
E29 Testicular dysfunction
0.000 0.331 0.669
M06 Other rheumatoid arthritis
0.002 0.332 0.666
E20 Hypoparathyroidism
0.000 0.337 0.662
E11.6 With other specified complications
0.000 0.347 0.653
J45.1 Nonallergic asthma
0.000 0.353 0.647
E22.0 Acromegaly and pituitary gigantism
0.000 0.354 0.646
M06.3 Rheumatoid nodule
0.000 0.355 0.645
E11.4 With neurological complications
0.000 0.359 0.641
E14.4 With neurological complications
0.000 0.361 0.639
E27.8 Other specified disorders of adrenal gland
0.000 0.363 0.637
K90 Intestinal malabsorption
0.000 0.377 0.623
E11.8 With unspecified complications
0.000 0.378 0.622
J45.8 Mixed asthma
0.000 0.379 0.621
K51.1 Ulcerative (chronic) ileocolitis
0.620 0.380 0.000
E11.9 Without complications
0.000 0.380 0.620
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.386 0.614
E23.1 Drug-induced hypopituitarism
0.000 0.386 0.614
E13.9 Without complications
0.000 0.387 0.613
E24.2 Drug-induced Cushing's syndrome
0.000 0.388 0.611
E11.2 With renal complications
0.000 0.395 0.605
M06.34 Rheumatoid nodule (Hand)
0.000 0.399 0.601
E28.2 Polycystic ovarian syndrome
0.000 0.403 0.597
G36 Other acute disseminated demyelination
0.591 0.408 0.000
E23.6 Other disorders of pituitary gland
0.000 0.409 0.591
E22.8 Other hyperfunction of pituitary gland
0.000 0.420 0.580
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.424 0.575
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.425 0.575
E24.3 Ectopic ACTH syndrome
0.000 0.425 0.575
E24.1 Nelson's syndrome
0.000 0.425 0.575
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.427 0.573
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.437 0.563
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.441 0.559
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.449 0.551
E13.8 With unspecified complications
0.000 0.451 0.549
E13.7 With multiple complications
0.000 0.451 0.549
E13.6 With other specified complications
0.000 0.451 0.549
E13.5 With peripheral circulatory complications
0.000 0.451 0.549
E13.4 With neurological complications
0.000 0.451 0.549
E13.2 With renal complications
0.000 0.451 0.549
E13.1 With ketoacidosis
0.000 0.451 0.549
E13.0 With coma
0.000 0.451 0.549
G37.8 Other specified demyelinating diseases of central nervous system
0.547 0.453 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.454 0.545
E07.8 Other specified disorders of thyroid
0.000 0.457 0.543
E22.1 Hyperprolactinaemia
0.000 0.457 0.543
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.458 0.542
E34.9 Endocrine disorder, unspecified
0.000 0.466 0.534
E13.3 With ophthalmic complications
0.000 0.471 0.529
E24.9 Cushing's syndrome, unspecified
0.000 0.471 0.529
E46 Unspecified protein-energy malnutrition
0.000 0.472 0.528
E24.8 Other Cushing's syndrome
0.000 0.472 0.527
E27.2 Addisonian crisis
0.000 0.473 0.527
K90.9 Intestinal malabsorption, unspecified
0.000 0.473 0.527
E25.9 Adrenogenital disorder, unspecified
0.000 0.479 0.521
E25.8 Other adrenogenital disorders
0.000 0.479 0.521
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.480 0.520
E45 Retarded development following protein-energy malnutrition
0.000 0.480 0.520
E43 Unspecified severe protein-energy malnutrition
0.000 0.480 0.520
E42 Marasmic kwashiorkor
0.000 0.480 0.520
E41 Nutritional marasmus
0.000 0.480 0.520
E40 Kwashiorkor
0.000 0.480 0.520
E34.0 Carcinoid syndrome
0.000 0.483 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E28.9 Ovarian dysfunction, unspecified
0.000 0.488 0.511
E28.8 Other ovarian dysfunction
0.000 0.488 0.511
E28.1 Androgen excess
0.000 0.488 0.511
E28.0 Oestrogen excess
0.000 0.488 0.511
G37.5 Concentric sclerosis [Balo]
0.510 0.490 0.000
G37.4 Subacute necrotising myelitis
0.510 0.490 0.000
G37.2 Central pontine myelinolysis
0.510 0.490 0.000
G37.1 Central demyelination of corpus callosum
0.510 0.490 0.000
G37.0 Diffuse sclerosis
0.510 0.490 0.000
E34.5 Androgen resistance syndrome
0.000 0.493 0.507
E34.4 Constitutional tall stature
0.000 0.493 0.507
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.493 0.507
E34.1 Other hypersecretion of intestinal hormones
0.000 0.493 0.507
E30.9 Disorder of puberty, unspecified
0.000 0.494 0.506
E30.8 Other disorders of puberty
0.000 0.494 0.506
E30.1 Precocious puberty
0.000 0.494 0.506
E30.0 Delayed puberty
0.000 0.494 0.506
E32.9 Disease of thymus, unspecified
0.000 0.494 0.506
E32.8 Other diseases of thymus
0.000 0.494 0.506
E32.1 Abscess of thymus
0.000 0.494 0.506
E32.0 Persistent hyperplasia of thymus
0.000 0.494 0.506
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.494 0.506
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.494 0.506
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.494 0.506
E26.8 Other hyperaldosteronism
0.000 0.494 0.506
E26.1 Secondary hyperaldosteronism
0.000 0.494 0.506
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.497 0.502
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.506 0.493
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.506 0.493
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.506 0.493
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.506 0.493
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.506 0.493
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.506 0.493
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.506 0.493
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.506 0.493
E31.9 Polyglandular dysfunction, unspecified
0.000 0.509 0.490
E31.8 Other polyglandular dysfunction
0.000 0.509 0.490
E31.1 Polyglandular hyperfunction
0.000 0.509 0.490
E34.3 Short stature, not elsewhere classified
0.000 0.512 0.488
E34.8 Other specified endocrine disorders
0.000 0.513 0.487
M06.8 Other specified rheumatoid arthritis
0.001 0.515 0.483
K90.8 Other intestinal malabsorption
0.000 0.516 0.484
E07.1 Dyshormogenetic goitre
0.000 0.517 0.483
E07.0 Hypersecretion of calcitonin
0.000 0.517 0.483
E29.9 Testicular dysfunction, unspecified
0.000 0.520 0.480
E29.8 Other testicular dysfunction
0.000 0.520 0.480
E29.0 Testicular hyperfunction
0.000 0.520 0.480
M06.2 Rheumatoid bursitis
0.001 0.521 0.477
M06.1 Adult-onset Still's disease
0.001 0.521 0.477
E20.8 Other hypoparathyroidism
0.000 0.525 0.475
E20.1 Pseudohypoparathyroidism
0.000 0.525 0.475
E20.0 Idiopathic hypoparathyroidism
0.000 0.525 0.475
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.475 0.525 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.530 0.470
E31.0 Autoimmune polyglandular failure
0.000 0.531 0.469
G36.0 Neuromyelitis optica [Devic]
0.465 0.535 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.537 0.462
M06.38 Rheumatoid nodule (Other)
0.000 0.537 0.462
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.537 0.462
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.537 0.462
M06.33 Rheumatoid nodule (Forearm)
0.000 0.537 0.462
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.537 0.462
E26.0 Primary hyperaldosteronism
0.000 0.543 0.457
E03 Other hypothyroidism
0.000 0.546 0.454
H20.9 Iridocyclitis, unspecified
0.450 0.550 0.000
M06.4 Inflammatory polyarthropathy
0.001 0.550 0.449
I10 Essential (primary) hypertension
0.000 0.553 0.447
E23.0 Hypopituitarism
0.000 0.553 0.447
K90.3 Pancreatic steatorrhoea
0.000 0.553 0.447
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.553 0.447
K90.1 Tropical sprue
0.000 0.553 0.447
E29.1 Testicular hypofunction
0.000 0.557 0.443
E20.9 Hypoparathyroidism, unspecified
0.000 0.568 0.432
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.569 0.431
G36.9 Acute disseminated demyelination, unspecified
0.424 0.576 0.000
G36.8 Other specified acute disseminated demyelination
0.424 0.576 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.424 0.576 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.582 0.418
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.584 0.416
H20 Iridocyclitis
0.396 0.604 0.000
E06 Thyroiditis
0.000 0.607 0.393
E28.3 Primary ovarian failure
0.000 0.624 0.376
E07.9 Disorder of thyroid, unspecified
0.000 0.626 0.374
E44.1 Mild protein-energy malnutrition
0.000 0.627 0.373
E44.0 Moderate protein-energy malnutrition
0.000 0.627 0.373
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.634 0.366
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.001 0.647 0.352
M06.88 Other specified rheumatoid arthritis (Other)
0.001 0.652 0.347
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.001 0.652 0.347
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.001 0.652 0.347
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.001 0.652 0.347
M06.84 Other specified rheumatoid arthritis (Hand)
0.001 0.652 0.347
M06.83 Other specified rheumatoid arthritis (Forearm)
0.001 0.652 0.347
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.001 0.652 0.347
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.001 0.652 0.347
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.001 0.652 0.347
H20.0 Acute and subacute iridocyclitis
0.346 0.654 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.001 0.657 0.342
M06.18 Adult-onset Still's disease (Other)
0.001 0.657 0.342
M06.17 Adult-onset Still's disease (Ankle and foot)
0.001 0.657 0.342
M06.16 Adult-onset Still's disease (Lower leg)
0.001 0.657 0.342
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.001 0.657 0.342
M06.14 Adult-onset Still's disease (Hand)
0.001 0.657 0.342
M06.13 Adult-onset Still's disease (Forearm)
0.001 0.657 0.342
M06.12 Adult-onset Still's disease (Upper arm)
0.001 0.657 0.342
M06.11 Adult-onset Still's disease (Shoulder region)
0.001 0.657 0.342
M06.10 Adult-onset Still's disease (Multiple sites)
0.001 0.657 0.342
M06.29 Rheumatoid bursitis (Site unspecified)
0.001 0.657 0.342
M06.28 Rheumatoid bursitis (Other)
0.001 0.657 0.342
M06.27 Rheumatoid bursitis (Ankle and foot)
0.001 0.657 0.342
M06.26 Rheumatoid bursitis (Lower leg)
0.001 0.657 0.342
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.001 0.657 0.342
M06.24 Rheumatoid bursitis (Hand)
0.001 0.657 0.342
M06.23 Rheumatoid bursitis (Forearm)
0.001 0.657 0.342
M06.22 Rheumatoid bursitis (Upper arm)
0.001 0.657 0.342
M06.21 Rheumatoid bursitis (Shoulder region)
0.001 0.657 0.342
M06.20 Rheumatoid bursitis (Multiple sites)
0.001 0.657 0.342
H20.8 Other iridocyclitis
0.330 0.670 0.000
K50-K52 Noninfective enteritis and colitis
0.327 0.673 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.001 0.674 0.325
E03.5 Myxoedema coma
0.000 0.674 0.325
E03.4 Atrophy of thyroid (acquired)
0.000 0.674 0.325
E03.3 Postinfectious hypothyroidism
0.000 0.674 0.325
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.674 0.325
H20.1 Chronic iridocyclitis
0.323 0.677 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.677 0.322
M06.48 Inflammatory polyarthropathy (Other)
0.001 0.677 0.322
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.001 0.677 0.322
M06.46 Inflammatory polyarthropathy (Lower leg)
0.001 0.677 0.322
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.001 0.677 0.322
M06.44 Inflammatory polyarthropathy (Hand)
0.001 0.677 0.322
M06.43 Inflammatory polyarthropathy (Forearm)
0.001 0.677 0.322
M06.42 Inflammatory polyarthropathy (Upper arm)
0.001 0.677 0.322
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.001 0.677 0.322
E03.1 Congenital hypothyroidism without goitre
0.000 0.678 0.322
E50-E64 Other nutritional deficiencies
0.000 0.691 0.308
E67 Other hyperalimentation
0.000 0.700 0.299
E68 Sequelae of hyperalimentation
0.000 0.700 0.299
E21.4 Other specified disorders of parathyroid gland
0.000 0.701 0.299
E03.8 Other specified hypothyroidism
0.000 0.705 0.295
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.001 0.711 0.288
H20.2 Lens-induced iridocyclitis
0.284 0.716 0.000
E06.4 Drug-induced thyroiditis
0.000 0.718 0.282
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.718 0.282
E06.0 Acute thyroiditis
0.000 0.718 0.282
E65 Localised adiposity
0.000 0.720 0.280
E06.1 Subacute thyroiditis
0.000 0.720 0.279
E06.5 Other chronic thyroiditis
0.000 0.732 0.268
E21.2 Other hyperparathyroidism
0.000 0.737 0.263
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.752 0.248
E21.3 Hyperparathyroidism, unspecified
0.000 0.759 0.240
E51 Thiamine deficiency
0.000 0.760 0.240
K50 Crohn's disease [regional enteritis]
0.239 0.761 0.000
H36.0 Diabetic retinopathy
0.000 0.764 0.236
E21.0 Primary hyperparathyroidism
0.000 0.767 0.233
E58 Dietary calcium deficiency
0.000 0.778 0.222
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.779 0.221
E63 Other nutritional deficiencies
0.000 0.779 0.221
E50 Vitamin A deficiency
0.000 0.779 0.221
E60 Dietary zinc deficiency
0.000 0.779 0.221
E59 Dietary selenium deficiency
0.000 0.779 0.221
E54 Ascorbic acid deficiency
0.000 0.779 0.221
E52 Niacin deficiency [pellagra]
0.000 0.779 0.221
E67.8 Other specified hyperalimentation
0.000 0.785 0.215
E67.3 Hypervitaminosis D
0.000 0.785 0.215
E67.2 Megavitamin-B6 syndrome
0.000 0.785 0.215
E67.1 Hypercarotenaemia
0.000 0.785 0.215
E67.0 Hypervitaminosis A
0.000 0.785 0.215
K50.9 Crohn's disease, unspecified
0.206 0.794 0.000
K50.1 Crohn's disease of large intestine
0.204 0.796 0.000
E56 Other vitamin deficiencies
0.000 0.798 0.202
E83 Disorders of mineral metabolism
0.200 0.798 0.002
E06.9 Thyroiditis, unspecified
0.000 0.805 0.195
E06.3 Autoimmune thyroiditis
0.000 0.805 0.195
H36 Retinal disorders in diseases classified elsewhere
0.000 0.809 0.191
E51.2 Wernicke's encephalopathy
0.000 0.809 0.190
K52 Other non-infective gastro-enteritis and colitis
0.183 0.816 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.177 0.823 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.828 0.172
E51.8 Other manifestations of thiamine deficiency
0.000 0.828 0.172
E51.1 Beriberi
0.000 0.828 0.172
K52.3 Indeterminate colitis
0.172 0.828 0.000
E61 Deficiency of other nutrient elements
0.000 0.830 0.170
H21 Other disorders of iris and ciliary body
0.166 0.834 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.164 0.836 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.841 0.159
E50.8 Other manifestations of vitamin A deficiency
0.000 0.841 0.159
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.841 0.159
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.841 0.159
E50.5 Vitamin A deficiency with night blindness
0.000 0.841 0.159
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.841 0.159
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.841 0.159
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.841 0.159
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.841 0.159
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.841 0.159
E63.9 Nutritional deficiency, unspecified
0.000 0.841 0.159
E63.8 Other specified nutritional deficiencies
0.000 0.841 0.159
E63.1 Imbalance of constituents of food intake
0.000 0.841 0.159
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.841 0.159
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.841 0.159
E64.8 Sequelae of other nutritional deficiencies
0.000 0.841 0.159
E64.3 Sequelae of rickets
0.000 0.841 0.159
E64.2 Sequelae of vitamin C deficiency
0.000 0.841 0.159
E64.1 Sequelae of vitamin A deficiency
0.000 0.841 0.159
E64.0 Sequelae of protein-energy malnutrition
0.000 0.841 0.159
H30-H36 Disorders of choroid and retina
0.000 0.842 0.158
E55 Vitamin D deficiency
0.000 0.843 0.157
K52.1 Toxic gastro-enteritis and colitis
0.154 0.846 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.855 0.145
E56.8 Deficiency of other vitamins
0.000 0.855 0.145
E56.0 Deficiency of vitamin E
0.000 0.855 0.145
E83.9 Disorder of mineral metabolism, unspecified
0.144 0.855 0.001
E83.8 Other disorders of mineral metabolism
0.144 0.855 0.001
E83.2 Disorders of zinc metabolism
0.144 0.855 0.001
E83.0 Disorders of copper metabolism
0.144 0.855 0.001
H33 Retinal detachments and breaks
0.000 0.857 0.143
E83.3 Disorders of phosphorus metabolism
0.141 0.859 0.001
K52.0 Gastro-enteritis and colitis due to radiation
0.138 0.862 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.863 0.137
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.137 0.863 0.000
H33.3 Retinal breaks without detachment
0.000 0.865 0.135
H21.8 Other specified disorders of iris and ciliary body
0.134 0.866 0.000
E04 Other non-toxic goitre
0.000 0.871 0.129
K50.0 Crohn's disease of small intestine
0.128 0.872 0.000
H30 Chorioretinal inflammation
0.000 0.873 0.127
H34 Retinal vascular occlusions
0.000 0.873 0.127
E56.1 Deficiency of vitamin K
0.000 0.874 0.126
H33.0 Retinal detachment with retinal break
0.000 0.875 0.125
E61.9 Deficiency of nutrient element, unspecified
0.000 0.878 0.122
E61.8 Deficiency of other specified nutrient elements
0.000 0.878 0.122
E61.7 Deficiency of multiple nutrient elements
0.000 0.878 0.122
E61.6 Vanadium deficiency
0.000 0.878 0.122
E61.5 Molybdenum deficiency
0.000 0.878 0.122
E61.4 Chromium deficiency
0.000 0.878 0.122
E61.3 Manganese deficiency
0.000 0.878 0.122
E61.0 Copper deficiency
0.000 0.878 0.122
H21.2 Degeneration of iris and ciliary body
0.122 0.878 0.000
M06.0 Seronegative rheumatoid arthritis
0.002 0.878 0.120
H33.1 Retinoschisis and retinal cysts
0.000 0.879 0.121
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.120 0.880 0.000
E53 Deficiency of other B group vitamins
0.000 0.880 0.119
H21.4 Pupillary membranes
0.119 0.881 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.119 0.881 0.000
H35.8 Other specified retinal disorders
0.000 0.881 0.119
H33.4 Traction detachment of retina
0.000 0.881 0.118
E83.4 Disorders of magnesium metabolism
0.117 0.883 0.000
H35 Other retinal disorders
0.000 0.883 0.117
H31 Other disorders of choroid
0.000 0.885 0.115
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.886 0.114
H17 Corneal scars and opacities
0.113 0.887 0.000
E55.0 Rickets, active
0.000 0.887 0.112
E61.1 Iron deficiency
0.000 0.891 0.108
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.108 0.892 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.108 0.892 0.000
H16 Keratitis
0.105 0.895 0.000
H30.9 Chorioretinal inflammation, unspecified
0.000 0.895 0.105
H34.8 Other retinal vascular occlusions
0.000 0.896 0.104
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.104 0.896 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.103 0.896 0.000
H15 Disorders of sclera
0.103 0.897 0.000
H35.6 Retinal haemorrhage
0.000 0.900 0.100
H34.2 Other retinal artery occlusions
0.000 0.901 0.099
H18 Other disorders of cornea
0.099 0.901 0.000
H35.4 Peripheral retinal degeneration
0.000 0.902 0.098
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.098 0.902 0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.098 0.902 0.000
H21.0 Hyphaema
0.095 0.905 0.000
E61.2 Magnesium deficiency
0.000 0.907 0.093
E04.8 Other specified non-toxic goitre
0.000 0.907 0.092
I10-I15 Hypertensive diseases
0.000 0.907 0.093
H21.1 Other vascular disorders of iris and ciliary body
0.092 0.908 0.000
H30.8 Other chorioretinal inflammations
0.000 0.909 0.091
H30.2 Posterior cyclitis
0.000 0.909 0.091
H30.1 Disseminated chorioretinal inflammation
0.000 0.909 0.091
H30.0 Focal chorioretinal inflammation
0.000 0.909 0.091
E83.5 Disorders of calcium metabolism
0.091 0.909 0.000
H34.0 Transient retinal artery occlusion
0.000 0.909 0.091
H31.1 Choroidal degeneration
0.000 0.910 0.090
H35.2 Other proliferative retinopathy
0.000 0.910 0.089
K50.8 Other Crohn's disease
0.089 0.911 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.002 0.912 0.086
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.002 0.912 0.086
M06.04 Seronegative rheumatoid arthritis (Hand)
0.002 0.912 0.086
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.002 0.912 0.086
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.002 0.912 0.086
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.086 0.914 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.086 0.914 0.000
E53.1 Pyridoxine deficiency
0.000 0.914 0.086
E53.0 Riboflavin deficiency
0.000 0.914 0.086
H31.0 Chorioretinal scars
0.000 0.914 0.086
H34.1 Central retinal artery occlusion
0.000 0.915 0.085
H34.9 Retinal vascular occlusion, unspecified
0.000 0.915 0.085
H35.1 Retinopathy of prematurity
0.000 0.916 0.084
H31.4 Choroidal detachment
0.000 0.917 0.083
H31.2 Hereditary choroidal dystrophy
0.000 0.917 0.083
E04.9 Non-toxic goitre, unspecified
0.000 0.917 0.083
H16.0 Corneal ulcer
0.083 0.917 0.000
H31.9 Disorder of choroid, unspecified
0.000 0.918 0.082
H15.9 Disorder of sclera, unspecified
0.082 0.918 0.000
H31.3 Choroidal haemorrhage and rupture
0.000 0.918 0.082
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.918 0.081
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.918 0.081
H17.1 Other central corneal opacity
0.081 0.919 0.000
H17.0 Adherent leukoma
0.081 0.919 0.000
H16.9 Keratitis, unspecified
0.081 0.919 0.000
H17.8 Other corneal scars and opacities
0.081 0.919 0.000
M45-M49 Spondylopathies
0.080 0.920 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.002 0.921 0.078
H18.6 Keratoconus
0.079 0.921 0.000
H18.3 Changes in corneal membranes
0.078 0.922 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.922 0.078
E04.0 Non-toxic diffuse goitre
0.000 0.924 0.076
H16.8 Other keratitis
0.076 0.924 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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