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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-28458373
log Bayes Factor = 91.1887
Chromosome 6   position 31,480,874  (GRCh37) Explore Affx-28458373 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.003 0.997
E10.1 With ketoacidosis
0.000 0.003 0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.004 0.996
E10.4 With neurological complications
0.000 0.004 0.996
E14.9 Without complications
0.000 0.011 0.989
M45 Ankylosing spondylitis
0.000 0.012 0.988
E14.3 With ophthalmic complications
0.000 0.015 0.985
I20.9 Angina pectoris, unspecified
0.000 0.017 0.983
I20 Angina pectoris
0.000 0.018 0.982
I20-I25 Ischaemic heart diseases
0.000 0.018 0.982
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.018 0.982
I22 Subsequent myocardial infarction
0.000 0.026 0.974
I25 Chronic ischaemic heart disease
0.000 0.042 0.958
I25.1 Atherosclerotic heart disease
0.000 0.047 0.953
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.048 0.952
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.049 0.951
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.050 0.950
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.057 0.943
I25.5 Ischaemic cardiomyopathy
0.000 0.064 0.936
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.064 0.936
M35.0 Sicca syndrome [Sjogren]
0.000 0.066 0.934
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.067 0.933
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.072 0.928
L40 Psoriasis
0.922 0.078 0.000
E06 Thyroiditis
0.000 0.080 0.920
M35 Other systemic involvement of connective tissue
0.000 0.082 0.918
E10.2 With renal complications
0.000 0.083 0.917
E16 Other disorders of pancreatic internal secretion
0.000 0.084 0.916
L40.0 Psoriasis vulgaris
0.894 0.106 0.000
E10.0 With coma
0.000 0.124 0.876
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.130 0.870
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.139 0.861
E06.3 Autoimmune thyroiditis
0.000 0.143 0.857
I20.0 Unstable angina
0.000 0.146 0.854
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.147 0.853
M35.1 Other overlap syndromes
0.000 0.149 0.851
E10.5 With peripheral circulatory complications
0.000 0.150 0.850
E14.8 With unspecified complications
0.000 0.158 0.842
E16.2 Hypoglycaemia, unspecified
0.000 0.167 0.833
I23 Certain current complications following acute myocardial infarction
0.000 0.183 0.817
E14.6 With other specified complications
0.000 0.184 0.816
M35.2 Behcet's disease
0.000 0.195 0.805
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.214 0.785
I21 Acute myocardial infarction
0.000 0.218 0.782
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.219 0.781
I20.1 Angina pectoris with documented spasm
0.000 0.221 0.779
M06 Other rheumatoid arthritis
0.000 0.226 0.774
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.228 0.772
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.238 0.762
M35.3 Polymyalgia rheumatica
0.000 0.239 0.761
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.243 0.756
I24 Other acute ischaemic heart diseases
0.000 0.251 0.749
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.257 0.743
E10.8 With unspecified complications
0.000 0.261 0.739
M34 Systemic sclerosis
0.000 0.267 0.733
E13 Other specified diabetes mellitus
0.000 0.272 0.728
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.273 0.727
E83.1 Disorders of iron metabolism
0.726 0.274 0.000
M20-M25 Other joint disorders
0.000 0.277 0.723
L40.5 Arthropathic psoriasis
0.722 0.278 0.000
E14.4 With neurological complications
0.000 0.280 0.720
M34.1 CR(E)ST syndrome
0.000 0.280 0.720
E14.1 With ketoacidosis
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.286 0.714
E14.2 Withrenal complications
0.000 0.291 0.709
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.291 0.708
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.291 0.708
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.291 0.708
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.291 0.708
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.291 0.708
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.291 0.708
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.291 0.708
M34.9 Systemic sclerosis, unspecified
0.000 0.296 0.704
L40.1 Generalised pustular psoriasis
0.700 0.300 0.000
I23.8 Other current complications following acute myocardial infarction
0.000 0.300 0.700
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.302 0.698
M35.8 Other specified systemic involvement of connective tissue
0.000 0.310 0.690
I25.6 Silent myocardial ischaemia
0.000 0.313 0.687
E06.9 Thyroiditis, unspecified
0.000 0.317 0.683
E15 Nondiabetic hypoglycaemic coma
0.000 0.319 0.681
I21.9 Acute myocardial infarction, unspecified
0.000 0.331 0.669
L40.4 Guttate psoriasis
0.661 0.339 0.000
L40.2 Acrodermatitis continua
0.661 0.339 0.000
E06.5 Other chronic thyroiditis
0.000 0.340 0.659
E06.4 Drug-induced thyroiditis
0.000 0.340 0.659
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.340 0.659
E06.1 Subacute thyroiditis
0.000 0.340 0.659
E06.0 Acute thyroiditis
0.000 0.340 0.659
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.342 0.658
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.342 0.658
M35.5 Multifocal fibrosclerosis
0.000 0.342 0.658
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.342 0.658
I22.8 Subsequent myocardial infarction of other sites
0.000 0.343 0.657
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.343 0.656
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.343 0.656
E16.4 Abnormal secretion of gastrin
0.000 0.343 0.656
E16.3 Increased secretion of glucagon
0.000 0.343 0.656
M34.8 Other forms of systemic sclerosis
0.000 0.347 0.653
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.349 0.651
L40.3 Pustulosis palmaris et plantaris
0.650 0.350 0.000
I25.3 Aneurysm of heart
0.000 0.352 0.648
E10.6 With other specified complications
0.000 0.353 0.647
M35.7 Hypermobility syndrome
0.000 0.354 0.646
E07 Other disorders of thyroid
0.000 0.371 0.629
E40-E46 Malnutrition
0.000 0.375 0.625
E65-E68 Obesity and other hyperalimentation
0.000 0.381 0.619
M45-M49 Spondylopathies
0.000 0.382 0.618
E14.0 With coma
0.000 0.382 0.618
L40.8 Other psoriasis
0.616 0.384 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.389 0.610
M05-M14 Inflammatory polyarthropathies
0.000 0.397 0.603
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.398 0.602
M22 Disorders of patella
0.000 0.399 0.601
M06.3 Rheumatoid nodule
0.000 0.401 0.599
M06.0 Seronegative rheumatoid arthritis
0.000 0.403 0.597
E16.1 Other hypoglycaemia
0.000 0.407 0.592
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.414 0.586
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.414 0.586
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.414 0.586
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.414 0.586
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.414 0.586
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.414 0.586
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.414 0.586
E03.1 Congenital hypothyroidism without goitre
0.000 0.417 0.583
M32 Systemic lupus erythematosus
0.000 0.418 0.582
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.430 0.570
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.434 0.566
M06.8 Other specified rheumatoid arthritis
0.000 0.435 0.565
E13.3 With ophthalmic complications
0.000 0.438 0.562
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.439 0.561
M06.2 Rheumatoid bursitis
0.000 0.445 0.555
M06.1 Adult-onset Still's disease
0.000 0.445 0.555
E05.8 Other thyrotoxicosis
0.000 0.455 0.545
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.459 0.541
M06.34 Rheumatoid nodule (Hand)
0.000 0.462 0.538
M34.0 Progressive systemic sclerosis
0.000 0.463 0.537
M22.8 Other disorders of patella
0.000 0.466 0.534
K90 Intestinal malabsorption
0.000 0.474 0.526
M22.9 Disorder of patella, unspecified
0.000 0.474 0.526
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.474 0.526
E65 Localised adiposity
0.000 0.474 0.526
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.477 0.523
E13.8 With unspecified complications
0.000 0.478 0.522
E13.7 With multiple complications
0.000 0.478 0.522
E13.6 With other specified complications
0.000 0.478 0.522
E13.5 With peripheral circulatory complications
0.000 0.478 0.522
E13.4 With neurological complications
0.000 0.478 0.522
E13.2 With renal complications
0.000 0.478 0.522
E13.1 With ketoacidosis
0.000 0.478 0.522
E13.0 With coma
0.000 0.478 0.522
I25.4 Coronary artery aneurysm
0.000 0.481 0.518
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E03.8 Other specified hypothyroidism
0.000 0.492 0.508
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.493 0.506
I24.1 Dressler's syndrome
0.000 0.495 0.505
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.505 0.495
M23.3 Other meniscus derangements
0.000 0.506 0.494
M23 Internal derangement of knee
0.000 0.508 0.492
E13.9 Without complications
0.000 0.513 0.487
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.523 0.477
M49 Spondylopathies in diseases classified elsewhere
0.000 0.525 0.475
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.528 0.472
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.535 0.464
M22.3 Other derangements of patella
0.000 0.540 0.460
G35 Multiple sclerosis
0.453 0.547 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.548 0.452
E07.1 Dyshormogenetic goitre
0.000 0.549 0.451
E07.0 Hypersecretion of calcitonin
0.000 0.549 0.451
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.552 0.448
E45 Retarded development following protein-energy malnutrition
0.000 0.552 0.448
E43 Unspecified severe protein-energy malnutrition
0.000 0.552 0.448
E42 Marasmic kwashiorkor
0.000 0.552 0.448
E41 Nutritional marasmus
0.000 0.552 0.448
E40 Kwashiorkor
0.000 0.552 0.448
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.554 0.446
E67 Other hyperalimentation
0.000 0.556 0.444
E68 Sequelae of hyperalimentation
0.000 0.556 0.444
M30 Polyarteritis nodosa and related conditions
0.000 0.557 0.443
M06.4 Inflammatory polyarthropathy
0.000 0.560 0.440
M80-M85 Disorders of bone density and structure
0.000 0.565 0.435
M22.0 Recurrent dislocation of patella
0.000 0.566 0.434
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.567 0.432
E50-E64 Other nutritional deficiencies
0.000 0.568 0.432
M22.1 Recurrent subluxation of patella
0.000 0.569 0.431
I24.8 Other forms of acute ischaemic heart disease
0.000 0.570 0.430
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.570 0.430
M06.38 Rheumatoid nodule (Other)
0.000 0.570 0.430
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.570 0.430
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.570 0.430
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.570 0.430
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.572 0.428
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.572 0.428
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.572 0.428
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.572 0.428
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.572 0.428
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.575 0.425
M32.8 Other forms of systemic lupus erythematosus
0.000 0.576 0.423
E07.9 Disorder of thyroid, unspecified
0.000 0.578 0.422
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.000 0.582 0.418
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.583 0.417
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.583 0.417
M08 Juvenile arthritis
0.000 0.583 0.417
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.585 0.415
M33 Dermatopolymyositis
0.000 0.585 0.414
M80 Osteoporosis with pathological fracture
0.000 0.592 0.408
M82 Osteoporosis in diseases classified elsewhere
0.000 0.594 0.406
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.595 0.405
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.595 0.405
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.595 0.405
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.595 0.405
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.595 0.405
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.595 0.405
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.595 0.405
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.595 0.405
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.595 0.405
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.597 0.403
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.000 0.598 0.402
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.599 0.401
E07.8 Other specified disorders of thyroid
0.000 0.600 0.400
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.600 0.400
M05 Seropositive rheumatoid arthritis
0.000 0.602 0.398
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.602 0.398
M06.18 Adult-onset Still's disease (Other)
0.000 0.602 0.398
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.602 0.398
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.602 0.398
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.602 0.398
M06.14 Adult-onset Still's disease (Hand)
0.000 0.602 0.398
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.602 0.398
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.602 0.398
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.602 0.398
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.602 0.398
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.602 0.398
M06.28 Rheumatoid bursitis (Other)
0.000 0.602 0.398
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.602 0.398
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.602 0.398
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.602 0.398
M06.24 Rheumatoid bursitis (Hand)
0.000 0.602 0.398
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.602 0.398
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.602 0.398
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.602 0.398
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.602 0.398
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.603 0.397
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.000 0.604 0.396
M82.1 Osteoporosis in endocrine disorders
0.000 0.614 0.386
G35-G37 Demyelinating diseases of the central nervous system
0.382 0.618 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.000 0.622 0.378
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.622 0.378
K90.3 Pancreatic steatorrhoea
0.000 0.623 0.377
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.623 0.377
K90.1 Tropical sprue
0.000 0.623 0.377
K90.8 Other intestinal malabsorption
0.000 0.623 0.377
M10 Gout
0.000 0.626 0.374
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.628 0.372
M06.33 Rheumatoid nodule (Forearm)
0.000 0.629 0.370
G37 Other demyelinating diseases of central nervous system
0.370 0.630 0.000
M11 Other crystal arthropathies
0.000 0.632 0.367
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.000 0.637 0.363
M36.3 Arthropathy in other blood disorders
0.000 0.637 0.363
M36.2 Haemophilic arthropathy
0.000 0.637 0.363
M36.1 Arthropathy in neoplastic disease
0.000 0.637 0.363
M36.0 Dermato(poly)myositis in neoplastic disease
0.000 0.637 0.363
G37.9 Demyelinating disease of central nervous system, unspecified
0.363 0.637 0.000
M12 Other specific arthropathies
0.000 0.640 0.360
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.641 0.358
E46 Unspecified protein-energy malnutrition
0.000 0.643 0.357
M23.37 Other meniscus derangements-Capsular lig
0.000 0.645 0.354
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.000 0.648 0.352
E51 Thiamine deficiency
0.000 0.648 0.352
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.648 0.351
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.650 0.350
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.651 0.348
M30.0 Polyarteritis nodosa
0.000 0.654 0.346
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.654 0.346
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.659 0.340
M49.4 Neuropathic spondylopathy
0.000 0.659 0.340
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.659 0.340
M49.2 Enterobacterial spondylitis
0.000 0.659 0.340
M49.1 Brucella spondylitis
0.000 0.659 0.340
M49.0 Tuberculosis of spine
0.000 0.659 0.340
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.000 0.663 0.337
M70-M79 Other soft tissue disorders
0.000 0.666 0.334
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.000 0.669 0.331
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.674 0.326
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.675 0.324
M23.4 Loose body in knee
0.000 0.676 0.324
E44.1 Mild protein-energy malnutrition
0.000 0.678 0.321
E44.0 Moderate protein-energy malnutrition
0.000 0.678 0.321
M00-M03 Infectious arthropathies
0.000 0.680 0.320
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.680 0.320
E67.8 Other specified hyperalimentation
0.000 0.681 0.318
E67.3 Hypervitaminosis D
0.000 0.681 0.318
E67.2 Megavitamin-B6 syndrome
0.000 0.681 0.318
E67.1 Hypercarotenaemia
0.000 0.681 0.318
E67.0 Hypervitaminosis A
0.000 0.681 0.318
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.682 0.317
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.682 0.317
M30.2 Juvenile polyarteritis
0.000 0.682 0.317
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.684 0.316
M14 Arthropathies in other diseases classified elsewhere
0.000 0.684 0.316
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.684 0.315
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.684 0.315
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.684 0.315
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.684 0.315
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.684 0.315
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.684 0.315
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.684 0.315
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.684 0.315
M23.6 Other spontaneous disruption of ligament(s) of knee
0.000 0.686 0.314
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.688 0.312
E61 Deficiency of other nutrient elements
0.000 0.689 0.311
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.690 0.310
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.690 0.310
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.690 0.310
M09.0 Juvenile arthritis in psoriasis
0.000 0.690 0.310
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.690 0.309
E63 Other nutritional deficiencies
0.000 0.690 0.309
E50 Vitamin A deficiency
0.000 0.690 0.309
E60 Dietary zinc deficiency
0.000 0.690 0.309
E59 Dietary selenium deficiency
0.000 0.690 0.309
E52 Niacin deficiency [pellagra]
0.000 0.690 0.309
E58 Dietary calcium deficiency
0.000 0.691 0.309
M22.10 Recurrent subluxation of patella, unspecified knee
0.000 0.691 0.309
M23.5 Chronic instability of knee
0.000 0.692 0.308
E56 Other vitamin deficiencies
0.000 0.693 0.307
M70.4 Prepatellar bursitis
0.000 0.695 0.305
M83 Adult osteomalacia
0.000 0.695 0.305
M05.8 Other seropositive rheumatoid arthritis
0.000 0.696 0.304
M23.9 Internal derangement of knee, unspecified
0.000 0.696 0.303
M60-M63 Disorders of muscles
0.000 0.697 0.303
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.000 0.700 0.300
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.700 0.300
M23.0 Cystic meniscus
0.000 0.700 0.300
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites
0.000 0.700 0.299
M08.9 Juvenile arthritis, unspecified
0.000 0.700 0.299
M08.8 Other juvenile arthritis
0.000 0.700 0.299
M08.4 Pauciarticular juvenile arthritis
0.000 0.700 0.299
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.700 0.299
M08.2 Juvenile arthritis with systemic onset
0.000 0.700 0.299
M08.1 Juvenile ankylosing spondylitis
0.000 0.700 0.299
M33.9 Dermatopolymyositis, unspecified
0.000 0.702 0.297
M33.0 Juvenile dermatomyositis
0.000 0.702 0.297
E11 Non-insulin-dependent diabetes mellitus
0.000 0.703 0.297
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.705 0.295
M22.4 Chondromalacia patellae
0.000 0.705 0.294
E51.2 Wernicke's encephalopathy
0.000 0.706 0.294
M80.4 Drug-induced osteoporosis with pathological fracture
0.000 0.707 0.293
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.000 0.707 0.293
M80.2 Osteoporosis of disuse with pathological fracture
0.000 0.707 0.293
M82.8 Osteoporosis in other diseases classified elsewhere
0.000 0.709 0.291
M82.0 Osteoporosis in multiple myelomatosis
0.000 0.709 0.291
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.000 0.709 0.291
G37.8 Other specified demyelinating diseases of central nervous system
0.288 0.712 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.714 0.286
M05.1 Rheumatoid lung disease
0.000 0.714 0.286
M05.0 Felty's syndrome
0.000 0.714 0.286
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.000 0.715 0.285
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.000 0.715 0.285
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.000 0.715 0.285
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.000 0.715 0.285
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.000 0.715 0.285
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.000 0.715 0.285
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.000 0.715 0.285
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.000 0.715 0.285
M08.0 Juvenile rheumatoid arthritis
0.000 0.716 0.284
E54 Ascorbic acid deficiency
0.000 0.716 0.284
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.001 0.717 0.283
M70.6 Trochanteric bursitis
0.000 0.718 0.282
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.718 0.282
M23.1 Discoid meniscus (congenital)
0.000 0.722 0.277
M82.19 Osteoporosis in endocrine disorders (Site unspecified)
0.000 0.723 0.276
M82.18 Osteoporosis in endocrine disorders (Other)
0.000 0.723 0.276
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)
0.000 0.723 0.276
M82.16 Osteoporosis in endocrine disorders (Lower leg)
0.000 0.723 0.276
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)
0.000 0.723 0.276
M82.14 Osteoporosis in endocrine disorders (Hand)
0.000 0.723 0.276
M82.13 Osteoporosis in endocrine disorders (Forearm)
0.000 0.723 0.276
M82.12 Osteoporosis in endocrine disorders (Upper arm)
0.000 0.723 0.276
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.000 0.725 0.275
E11.0 With coma
0.000 0.729 0.271
M80.0 Postmenopausal osteoporosis with pathological fracture
0.000 0.731 0.268
M10.4 Other secondary gout
0.000 0.732 0.268
M10.3 Gout due to impairment of renal function
0.000 0.732 0.268
M10.2 Drug-induced gout
0.000 0.732 0.268
M10.1 Lead-induced gout
0.000 0.732 0.268
M10.9 Gout, unspecified
0.000 0.733 0.267
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.000 0.733 0.267
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.733 0.267
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.000 0.733 0.267
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.000 0.733 0.267
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.000 0.733 0.267
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.000 0.733 0.267
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.733 0.267
M33.2 Polymyositis
0.000 0.733 0.266
G37.5 Concentric sclerosis [Balo]
0.266 0.734 0.000
G37.4 Subacute necrotising myelitis
0.266 0.734 0.000
G37.2 Central pontine myelinolysis
0.266 0.734 0.000
G37.1 Central demyelination of corpus callosum
0.266 0.734 0.000
G37.0 Diffuse sclerosis
0.266 0.734 0.000
M80.8 Other osteoporosis with pathological fracture
0.000 0.734 0.265
M11.1 Familial chondrocalcinosis
0.000 0.736 0.264
M11.0 Hydroxyapatite deposition disease
0.000 0.736 0.264
M25 Other joint disorders, not elsewhere classified
0.000 0.737 0.263
M05.2 Rheumatoid vasculitis
0.000 0.739 0.261
M22.2 Patellofemoral disorders
0.000 0.740 0.260
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.741 0.258
M12.5 Traumatic arthropathy
0.000 0.741 0.258
M12.4 Intermittent hydrarthrosis
0.000 0.741 0.258
M12.1 Kaschin-Beck disease
0.000 0.741 0.258
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.741 0.258
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.742 0.258
G36 Other acute disseminated demyelination
0.256 0.744 0.000
M91-M94 Chondropathies
0.000 0.745 0.255
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.746 0.254
H36.0 Diabetic retinopathy
0.000 0.747 0.253
M11.9 Crystal arthropathy, unspecified
0.000 0.747 0.252
E51.9 Thiamine deficiency, unspecified
0.000 0.748 0.252
E51.8 Other manifestations of thiamine deficiency
0.000 0.748 0.252
E51.1 Beriberi
0.000 0.748 0.252
M07 Psoriatic and enteropathic arthropathies
0.001 0.749 0.250
I25.2 Old myocardial infarction
0.000 0.750 0.250
L40-L45 Papulosquamous disorders
0.249 0.750 0.001
M40-M43 Deforming dorsopathies
0.000 0.750 0.250
M25.4 Effusion of joint
0.000 0.752 0.248
M70.2 Olecranon bursitis
0.000 0.753 0.247
M23.43 Loose body in knee-Med lig/oth men
0.000 0.753 0.247
M11.2 Other chondrocalcinosis
0.000 0.754 0.246
E20-E35 Disorders of other endocrine glands
0.000 0.755 0.245
M49.09 Tuberculosis of spine (Site unspecified)
0.000 0.756 0.244
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.000 0.756 0.244
M49.07 Tuberculosis of spine (Lumbosacral region)
0.000 0.756 0.244
M49.06 Tuberculosis of spine (Lumbar region)
0.000 0.756 0.244
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.000 0.756 0.244
M49.04 Tuberculosis of spine (Thoracic region)
0.000 0.756 0.244
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.000 0.756 0.244
M49.02 Tuberculosis of spine (Cervical region)
0.000 0.756 0.244
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.000 0.756 0.244
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.000 0.756 0.244
M49.19 Brucella spondylitis (Site unspecified)
0.000 0.756 0.244
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.000 0.756 0.244
M49.17 Brucella spondylitis (Lumbosacral region)
0.000 0.756 0.244
M49.16 Brucella spondylitis (Lumbar region)
0.000 0.756 0.244
M49.15 Brucella spondylitis (Thoracolumbar region)
0.000 0.756 0.244
M49.14 Brucella spondylitis (Thoracic region)
0.000 0.756 0.244
M49.13 Brucella spondylitis (Cervicothoracic region)
0.000 0.756 0.244
M49.12 Brucella spondylitis (Cervical region)
0.000 0.756 0.244
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.000 0.756 0.244
M49.10 Brucella spondylitis (Multiple sites in spine)
0.000 0.756 0.244
M49.29 Enterobacterial spondylitis (Site unspecified)
0.000 0.756 0.244
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)
0.000 0.756 0.244
M49.27 Enterobacterial spondylitis (Lumbosacral region)
0.000 0.756 0.244
M49.26 Enterobacterial spondylitis (Lumbar region)
0.000 0.756 0.244
M49.25 Enterobacterial spondylitis (Thoracolumbar region)
0.000 0.756 0.244
M49.24 Enterobacterial spondylitis (Thoracic region)
0.000 0.756 0.244
M49.23 Enterobacterial spondylitis (Cervicothoracic region)
0.000 0.756 0.244
M49.22 Enterobacterial spondylitis (Cervical region)
0.000 0.756 0.244
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)
0.000 0.756 0.244

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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