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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

Affx-52368559
log Bayes Factor = 10.3508
Chromosome 6   position 31,237,764  (GRCh37) Explore Affx-52368559 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.002 0.998
L40.5 Arthropathic psoriasis
0.000 0.003 0.997
M06 Other rheumatoid arthritis
0.000 0.012 0.988
E10-E14 Diabetes mellitus
0.000 0.012 0.988
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.017 0.983
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.017 0.983
E10 Insulin-dependent diabetes mellitus
0.000 0.017 0.983
# Top node
0.000 0.018 0.982
D50-D53 Nutritional anaemias
0.000 0.018 0.982
D50 Iron deficiency anaemia
0.000 0.020 0.980
D50.9 Iron deficiency anaemia, unspecified
0.000 0.020 0.980
M05-M14 Inflammatory polyarthropathies
0.000 0.027 0.973
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.027 0.972
E10.9 Without complications
0.000 0.032 0.968
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.056 0.944
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.058 0.942
L08 Other local infections of skin and subcutaneous tissue
0.000 0.059 0.941
D60-D64 Aplastic and other anaemias
0.000 0.074 0.926
N43.3 Hydrocele, unspecified
0.920 0.080 0.000
N40-N51 Diseases of male genital organs
0.919 0.081 0.000
N43 Hydrocele and spermatocele
0.919 0.081 0.000
N48 Other disorders of penis
0.917 0.083 0.000
N48.6 Balanitis xerotica obliterans
0.907 0.093 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.095 0.905
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.099 0.901
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.108 0.892
E10.3 With ophthalmic complications
0.000 0.111 0.889
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.116 0.884
D64 Other anaemias
0.000 0.120 0.880
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.120 0.880
Chapter VI Diseases of the nervous system
0.000 0.123 0.877
M07 Psoriatic and enteropathic arthropathies
0.000 0.129 0.871
N41 Inflammatory diseases of prostate
0.864 0.136 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.141 0.859
L57.0 Actinic keratosis
0.000 0.145 0.855
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.148 0.852
D64.9 Anaemia, unspecified
0.000 0.152 0.848
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.155 0.845
M06.0 Seronegative rheumatoid arthritis
0.000 0.157 0.843
E06 Thyroiditis
0.000 0.161 0.839
E40-E46 Malnutrition
0.000 0.168 0.832
N48.0 Leukoplakia of penis
0.830 0.170 0.000
L40.0 Psoriasis vulgaris
0.000 0.171 0.829
Chapter VII Diseases of the eye and adnexa
0.000 0.177 0.823
M05 Seropositive rheumatoid arthritis
0.000 0.181 0.819
G30-G32 Other degenerative diseases of the nervous system
0.000 0.184 0.816
G35 Multiple sclerosis
0.000 0.184 0.816
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.191 0.809
N50 Other disorders of male genital organs
0.805 0.195 0.000
E50-E64 Other nutritional deficiencies
0.000 0.196 0.804
M07.3 Other psoriatic arthropathies
0.000 0.203 0.797
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.206 0.794
N42 Other disorders of prostate
0.790 0.210 0.000
E70-E90 Metabolic disorders
0.000 0.215 0.785
D51 Vitamin B12 deficiency anaemia
0.000 0.216 0.784
N48.8 Other specified disorders of penis
0.776 0.224 0.000
E14 Unspecified diabetes mellitus
0.000 0.226 0.774
H40-H42 Glaucoma
0.000 0.227 0.773
L81 Other disorders of pigmentation
0.000 0.229 0.771
E10.5 With peripheral circulatory complications
0.000 0.232 0.768
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.235 0.765
N50.8 Other specified disorders of male genital organs
0.765 0.235 0.000
H43-H45 Disorders of vitreous body and globe
0.000 0.245 0.755
N48.2 Other inflammatory disorders of penis
0.754 0.246 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.247 0.753
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.254 0.746
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.256 0.744
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.257 0.743
Chapter I Certain infectious and parasitic diseases
0.000 0.258 0.742
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.260 0.740
N47 Redundant prepuce, phimosis and paraphimosis
0.740 0.260 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.261 0.739
H53-H54 Visual disturbances and blindness
0.000 0.261 0.739
H40 Glaucoma
0.000 0.263 0.737
N41.9 Inflammatory disease of prostate, unspecified
0.736 0.263 0.000
C44 Other malignant neoplasms of skin
0.000 0.264 0.736
N41.0 Acute prostatitis
0.736 0.264 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.267 0.733
L20-L30 Dermatitis and eczema
0.000 0.267 0.733
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.268 0.732
D61 Other aplastic anaemias
0.000 0.269 0.731
D72 Other disorders of white blood cells
0.000 0.270 0.730
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.271 0.729
N42.8 Other specified disorders of prostate
0.729 0.271 0.000
E07 Other disorders of thyroid
0.000 0.272 0.728
L85 Other epidermal thickening
0.000 0.273 0.727
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.275 0.725
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.000 0.275 0.725
E06.3 Autoimmune thyroiditis
0.000 0.275 0.725
N41.1 Chronic prostatitis
0.719 0.281 0.000
L91 Hypertrophic disorders of skin
0.000 0.282 0.718
L40.8 Other psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E03.8 Other specified hypothyroidism
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
C44.3 Skin of other and unspecified parts of face
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.716
L41 Parapsoriasis
0.000 0.284 0.716
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.716
C44.4 Skin of scalp and neck
0.000 0.284 0.716
L10-L14 Bullous disorders
0.000 0.284 0.716
E10.4 With neurological complications
0.000 0.285 0.715
E46 Unspecified protein-energy malnutrition
0.000 0.288 0.712
C44.7 Skin of lower limb, including hip
0.000 0.288 0.712
M11 Other crystal arthropathies
0.000 0.289 0.711
C44.1 Skin of eyelid, including canthus
0.000 0.290 0.710
D52 Folate deficiency anaemia
0.000 0.291 0.709
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.292 0.708
M06.8 Other specified rheumatoid arthritis
0.000 0.292 0.708
M06.2 Rheumatoid bursitis
0.000 0.292 0.708
M06.1 Adult-onset Still's disease
0.000 0.292 0.708
E12 Malnutrition-related diabetes mellitus
0.000 0.292 0.708
E86 Volume depletion
0.000 0.292 0.708
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.293 0.707
D55-D59 Haemolytic anaemias
0.000 0.295 0.705
E10.8 With unspecified complications
0.000 0.295 0.705
E10.7 With multiple complications
0.000 0.295 0.705
E10.6 With other specified complications
0.000 0.295 0.705
E10.2 With renal complications
0.000 0.295 0.705
E10.0 With coma
0.000 0.295 0.705
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.296 0.704
D53 Other nutritional anaemias
0.000 0.296 0.704
L81.4 Other melanin hyperpigmentation
0.000 0.297 0.703
H43 Disorders of vitreous body
0.000 0.297 0.703
D50.1 Sideropenic dysphagia
0.000 0.297 0.703
N45 Orchitis and epididymitis
0.702 0.298 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.299 0.700
E89.0 Postprocedural hypothyroidism
0.000 0.300 0.700
N48.9 Disorder of penis, unspecified
0.699 0.301 0.000
M12 Other specific arthropathies
0.000 0.302 0.698
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.302 0.698
M08 Juvenile arthritis
0.000 0.302 0.698
L04 Acute lymphadenitis
0.000 0.303 0.697
L01 Impetigo
0.000 0.303 0.697
L00 Staphylococcal scalded skin syndrome
0.000 0.303 0.697
M10 Gout
0.000 0.303 0.697
E10.1 With ketoacidosis
0.000 0.303 0.697
E13 Other specified diabetes mellitus
0.000 0.303 0.697
H53 Visual disturbances
0.000 0.305 0.695
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.306 0.694
H40.0 Glaucoma suspect
0.000 0.307 0.693
E53 Deficiency of other B group vitamins
0.000 0.307 0.693
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.308 0.692
M14 Arthropathies in other diseases classified elsewhere
0.000 0.309 0.691
M00-M03 Infectious arthropathies
0.000 0.309 0.691
G30 Alzheimer's disease
0.000 0.314 0.686
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.316 0.684
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.316 0.684
L05 Pilonidal cyst
0.000 0.317 0.683
M06.3 Rheumatoid nodule
0.000 0.319 0.681
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.321 0.679
E65-E68 Obesity and other hyperalimentation
0.000 0.321 0.679
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.323 0.677
L58 Radiodermatitis
0.000 0.323 0.677
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.323 0.677
L55 Sunburn
0.000 0.323 0.677
H40.9 Glaucoma, unspecified
0.000 0.324 0.676
D75 Other diseases of blood and blood-forming organs
0.000 0.324 0.676
L08.1 Erythrasma
0.000 0.325 0.675
L08.0 Pyoderma
0.000 0.325 0.675
L83 Acanthosis nigricans
0.000 0.330 0.670
M45-M49 Spondylopathies
0.000 0.331 0.669
D73 Diseases of spleen
0.000 0.333 0.667
E04 Other non-toxic goitre
0.000 0.334 0.666
L90 Atrophic disorders of skin
0.000 0.335 0.665
B35-B49 Mycoses
0.000 0.336 0.664
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.336 0.664
G70-G73 Diseases of myoneural junction and muscle
0.000 0.339 0.661
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.340 0.660
N51 Disorders of male genital organs in diseases classified elsewhere
0.659 0.341 0.000
N46 Male infertility
0.659 0.341 0.000
N44 Torsion of testis
0.659 0.341 0.000
N43.4 Spermatocele
0.659 0.341 0.000
N43.2 Other hydrocele
0.659 0.341 0.000
N43.1 Infected hydrocele
0.659 0.341 0.000
N43.0 Encysted hydrocele
0.659 0.341 0.000
B25-B34 Other viral diseases
0.000 0.342 0.658
G37 Other demyelinating diseases of central nervous system
0.000 0.342 0.658
N48.5 Ulcer of penis
0.657 0.343 0.000
N48.3 Priapism
0.657 0.343 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.343 0.657
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.344 0.656
D72.8 Other specified disorders of white blood cells
0.000 0.350 0.650
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.351 0.649
L57.5 Actinic granuloma
0.000 0.351 0.649
L57.4 Cutis laxa senilis
0.000 0.351 0.649
L57.3 Poikiloderma of Civatte
0.000 0.351 0.649
L57.2 Cutis rhomboidalis nuchae
0.000 0.351 0.649
L57.1 Actinic reticuloid
0.000 0.351 0.649
D80-D89 Certain disorders involving the immune mechanism
0.000 0.357 0.642
G81 Hemiplegia
0.000 0.358 0.642
M65-M68 Disorders of synovium and tendon
0.000 0.359 0.641
D50.8 Other iron deficiency anaemias
0.000 0.362 0.638
B37 Candidiasis
0.000 0.362 0.638
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.364 0.636
M45 Ankylosing spondylitis
0.000 0.365 0.635
M60-M63 Disorders of muscles
0.000 0.365 0.635
H53.2 Diplopia
0.000 0.365 0.635
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.367 0.633
D64.8 Other specified anaemias
0.000 0.369 0.631
D64.4 Congenital dyserythropoietic anaemia
0.000 0.369 0.631
D64.3 Other sideroblastic anaemias
0.000 0.369 0.631
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.369 0.631
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.369 0.631
D64.0 Hereditary sideroblastic anaemia
0.000 0.369 0.631
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.000 0.369 0.631
L94 Other localised connective tissue disorders
0.000 0.369 0.631
L87 Transepidermal elimination disorders
0.000 0.369 0.631
L88 Pyoderma gangrenosum
0.000 0.369 0.631
L86 Keratoderma in diseases classified elsewhere
0.000 0.369 0.631
L80 Vitiligo
0.000 0.369 0.631
N50.9 Disorder of male genital organs, unspecified
0.630 0.370 0.000
E14.9 Without complications
0.000 0.370 0.630
G31.8 Other specified degenerative diseases of nervous system
0.000 0.371 0.629
M80-M85 Disorders of bone density and structure
0.000 0.371 0.629
E05.9 Thyrotoxicosis, unspecified
0.000 0.372 0.628
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.372 0.628
L93 Lupus erythematosus
0.000 0.372 0.627
L95 Vasculitis limited to skin, not elsewhere classified
0.000 0.373 0.627
L84 Corns and callosities
0.000 0.373 0.627
M07.6 Other enteropathic arthropathies
0.000 0.376 0.624
M07.5 Arthropathy in ulcerative colitis
0.000 0.376 0.624
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.376 0.624
M07.2 Psoriatic spondylitis
0.000 0.376 0.624
M07.1 Arthritis mutilans
0.000 0.376 0.624
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.376 0.624
L89 Decubitus ulcer
0.000 0.377 0.623
L03 Cellulitis
0.000 0.379 0.621
C50.9 Breast, unspecified
0.621 0.379 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.620 0.380 0.000
H43.8 Other disorders of vitreous body
0.000 0.380 0.620
N41.8 Other inflammatory diseases of prostate
0.619 0.381 0.000
N41.3 Prostatocystitis
0.619 0.381 0.000
N41.2 Abscess of prostate
0.619 0.381 0.000
L91.8 Other hypertrophic disorders of skin
0.000 0.382 0.618
D74 Methaemoglobinaemia
0.000 0.384 0.616
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.384 0.616
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.384 0.616
H43.3 Other vitreous opacities
0.000 0.385 0.615
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.386 0.614
C50 Malignant neoplasm of breast
0.614 0.386 0.001
E53.8 Deficiency of other specified B group vitamins
0.000 0.387 0.613
E20-E35 Disorders of other endocrine glands
0.000 0.388 0.612
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.389 0.611
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.389 0.611
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.389 0.611
L50-L54 Urticaria and erythema
0.000 0.392 0.608
G36 Other acute disseminated demyelination
0.000 0.394 0.606
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.395 0.604
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.395 0.604
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.395 0.604
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.395 0.604
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.395 0.604
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.395 0.604
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.395 0.604
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.395 0.604
C44.6 Skin of upper limb, including shoulder
0.000 0.396 0.604
G62 Other polyneuropathies
0.000 0.397 0.602
E06.9 Thyroiditis, unspecified
0.000 0.398 0.602
E06.5 Other chronic thyroiditis
0.000 0.398 0.602
E06.4 Drug-induced thyroiditis
0.000 0.398 0.602
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.398 0.602
E06.1 Subacute thyroiditis
0.000 0.398 0.602
E06.0 Acute thyroiditis
0.000 0.398 0.602
B37.8 Candidiasis of other sites
0.000 0.399 0.601
L29 Pruritus
0.000 0.401 0.599
G80 Infantile cerebral palsy
0.000 0.401 0.598
C50.4 Upper-outer quadrant of breast
0.598 0.402 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.402 0.598
B34 Viral infection of unspecified site
0.000 0.402 0.598
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.403 0.597
H53.1 Subjective visual disturbances
0.000 0.403 0.597
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.404 0.596
E45 Retarded development following protein-energy malnutrition
0.000 0.404 0.596
E43 Unspecified severe protein-energy malnutrition
0.000 0.404 0.596
E42 Marasmic kwashiorkor
0.000 0.404 0.596
E41 Nutritional marasmus
0.000 0.404 0.596
E40 Kwashiorkor
0.000 0.404 0.596
D70 Agranulocytosis
0.000 0.406 0.594
M95.0 Acquired deformity of nose
0.000 0.407 0.593
L42 Pityriasis rosea
0.000 0.407 0.593
G30.9 Alzheimer's disease, unspecified
0.000 0.408 0.592
L85.9 Epidermal thickening, unspecified
0.000 0.408 0.592
D61.9 Aplastic anaemia, unspecified
0.000 0.409 0.591
E88 Other metabolic disorders
0.000 0.412 0.587
M05.8 Other seropositive rheumatoid arthritis
0.000 0.413 0.587
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.413 0.587
M05.2 Rheumatoid vasculitis
0.000 0.413 0.587
M05.1 Rheumatoid lung disease
0.000 0.413 0.587
M05.0 Felty's syndrome
0.000 0.413 0.587
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.413 0.587
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.414 0.586
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.415 0.585
L90.0 Lichen sclerosus et atrophicus
0.000 0.415 0.585
C44.2 Skin of ear and external auricular canal
0.000 0.416 0.584
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.417 0.583
D62 Acute posthaemorrhagic anaemia
0.000 0.418 0.582
E05.5 Thyroid crisis or storm
0.000 0.420 0.580
E05.4 Thyrotoxicosis factitia
0.000 0.420 0.580
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.420 0.580
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.420 0.580
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.420 0.580
H30-H36 Disorders of choroid and retina
0.000 0.420 0.580
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.421 0.578
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.424 0.576
E63 Other nutritional deficiencies
0.000 0.424 0.576
E56 Other vitamin deficiencies
0.000 0.424 0.576
E51 Thiamine deficiency
0.000 0.424 0.576
E50 Vitamin A deficiency
0.000 0.424 0.576
E60 Dietary zinc deficiency
0.000 0.424 0.576
E59 Dietary selenium deficiency
0.000 0.424 0.576
E58 Dietary calcium deficiency
0.000 0.424 0.576
E54 Ascorbic acid deficiency
0.000 0.424 0.576
E52 Niacin deficiency [pellagra]
0.000 0.424 0.576
Chapter XXII Codes for special purposes
0.000 0.425 0.574
M07.38 Other psoriatic arthropathies (Other)
0.000 0.428 0.571
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.428 0.571
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.428 0.571
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.428 0.571
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.428 0.571
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.428 0.571
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.428 0.571
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.428 0.571
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.428 0.571
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.430 0.570
L05.0 Pilonidal cyst with abscess
0.000 0.432 0.568
G81.9 Hemiplegia, unspecified
0.000 0.432 0.568
L28 Lichen simplex chronicus and prurigo
0.000 0.432 0.568
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.432 0.567
B37.0 Candidal stomatitis
0.000 0.433 0.567
C44.0 Skin of lip
0.000 0.434 0.566
N42.3 Dysplasia of prostate
0.566 0.434 0.000
N42.0 Calculus of prostate
0.566 0.434 0.000
M91-M94 Chondropathies
0.000 0.434 0.566
L43 Lichen planus
0.000 0.434 0.565
E84 Cystic fibrosis
0.000 0.437 0.563
E79 Disorders of purine and pyrimidine metabolism
0.000 0.437 0.563
E77 Disorders of glycoprotein metabolism
0.000 0.437 0.563
E76 Disorders of glycosaminoglycan metabolism
0.000 0.437 0.563
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.437 0.563
E73 Lactose intolerance
0.000 0.437 0.563
E72 Other disorders of amino-acid metabolism
0.000 0.437 0.563
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.437 0.563
E70 Disorders of aromatic amino-acid metabolism
0.000 0.437 0.563
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.437 0.563
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.438 0.562
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.438 0.562
D51.2 Transcobalamin II deficiency
0.000 0.438 0.562
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.438 0.562
E89.2 Postprocedural hypoparathyroidism
0.000 0.438 0.561
L98.4 Chronic ulcer of skin, not elsewhere classified
0.000 0.439 0.561
L85.8 Other specified epidermal thickening
0.000 0.440 0.560
H44 Disorders of globe
0.000 0.442 0.558
H10-H13 Disorders of conjunctiva
0.000 0.442 0.558
D75.1 Secondary polycythaemia
0.000 0.443 0.557
G70 Myasthenia gravis and other myoneural disorders
0.000 0.444 0.556
E04.2 Non-toxic multinodular goitre
0.000 0.444 0.556
N42.2 Atrophy of prostate
0.556 0.444 0.000
E14.8 With unspecified complications
0.000 0.445 0.555
E14.7 With multiple complications
0.000 0.445 0.555
E14.6 With other specified complications
0.000 0.445 0.555
E14.5 With peripheral circulatory complications
0.000 0.445 0.555
E14.4 With neurological complications
0.000 0.445 0.555
E14.2 Withrenal complications
0.000 0.445 0.555
E14.1 With ketoacidosis
0.000 0.445 0.555
E14.0 With coma
0.000 0.445 0.555
C50.3 Lower-inner quadrant of breast
0.555 0.445 0.000
H42 Glaucoma in diseases classified elsewhere
0.000 0.446 0.554
B34.9 Viral infection, unspecified
0.000 0.446 0.554
L81.8 Other specified disorders of pigmentation
0.000 0.447 0.553
L81.7 Pigmented purpuric dermatosis
0.000 0.447 0.553
L81.6 Other disorders of diminished melanin formation
0.000 0.447 0.553
L81.5 Leukoderma, not elsewhere classified
0.000 0.447 0.553
L81.3 Cafe au lait spots
0.000 0.447 0.553
L81.2 Freckles
0.000 0.447 0.553
L81.1 Chloasma
0.000 0.447 0.553
L81.0 Postinflammatory hyperpigmentation
0.000 0.447 0.553
M80 Osteoporosis with pathological fracture
0.000 0.447 0.552
E55 Vitamin D deficiency
0.000 0.447 0.552
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.449 0.551
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.450 0.550
A30-A49 Other bacterial diseases
0.000 0.450 0.550
N42.9 Disorder of prostate, unspecified
0.548 0.452 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.547 0.453 0.000
B99-B99 Other infectious diseases
0.000 0.453 0.547
E61 Deficiency of other nutrient elements
0.000 0.455 0.545
D73.0 Hyposplenism
0.000 0.455 0.545
H40.5 Glaucoma secondary to other eye disorders
0.000 0.457 0.543
H36 Retinal disorders in diseases classified elsewhere
0.000 0.457 0.543
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.457 0.542
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.458 0.542
E14.3 With ophthalmic complications
0.000 0.458 0.542
H40.2 Primary angle-closure glaucoma
0.000 0.460 0.540
M99 Biomechanical lesions, not elsewhere classified
0.000 0.460 0.540
H53.9 Visual disturbance, unspecified
0.000 0.460 0.539
G62.9 Polyneuropathy, unspecified
0.000 0.463 0.537
N50.0 Atrophy of testis
0.534 0.465 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.466 0.534
B65-B83 Helminthiases
0.000 0.466 0.534
E07.9 Disorder of thyroid, unspecified
0.000 0.466 0.534
E27 Other disorders of adrenal gland
0.000 0.467 0.533
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.468 0.532
B50-B64 Protozoal diseases
0.000 0.468 0.532
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.468 0.532
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.468 0.532
A75-A79 Rickettsioses
0.000 0.468 0.532
A70-A74 Other diseases caused by chlamydiae
0.000 0.468 0.532
A65-A69 Other spirochaetal diseases
0.000 0.468 0.532
A20-A28 Certain zoonotic bacterial diseases
0.000 0.468 0.532
A15-A19 Tuberculosis
0.000 0.468 0.532
G31.2 Degeneration of nervous system due to alcohol
0.000 0.470 0.530
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.470 0.530
G31.0 Circumscribed brain atrophy
0.000 0.470 0.530
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.470 0.530
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.470 0.530
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.470 0.530
E89.5 Postprocedural testicular hypofunction
0.000 0.470 0.530
E89.4 Postprocedural ovarian failure
0.000 0.470 0.530
E89.1 Postprocedural hypoinsulinaemia
0.000 0.470 0.530
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.471 0.529
E89.3 Postprocedural hypopituitarism
0.000 0.471 0.529
H40.6 Glaucoma secondary to drugs
0.000 0.471 0.529
H40.4 Glaucoma secondary to eye inflammation
0.000 0.471 0.529
H40.3 Glaucoma secondary to eye trauma
0.000 0.471 0.529
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.472 0.528
L03.3 Cellulitis of trunk
0.000 0.472 0.528
C44.8 Overlapping lesion of skin
0.000 0.472 0.528
N48.4 Impotence of organic origin
0.527 0.473 0.000
M13 Other arthritis
0.000 0.473 0.527
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.473 0.526
L25 Unspecified contact dermatitis
0.000 0.474 0.525
L24 Irritant contact dermatitis
0.000 0.474 0.525
L23 Allergic contact dermatitis
0.000 0.474 0.525
L21 Seborrhoeic dermatitis
0.000 0.474 0.525
L20 Atopic dermatitis
0.000 0.474 0.525
L26 Exfoliative dermatitis
0.000 0.474 0.525
L22 Diaper [napkin] dermatitis
0.000 0.474 0.525
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.474 0.525
L29.0 Pruritus ani
0.000 0.475 0.525
H53.4 Visual field defects
0.000 0.475 0.525
D61.8 Other specified aplastic anaemias
0.000 0.476 0.524
D61.3 Idiopathic aplastic anaemia
0.000 0.476 0.524
D61.2 Aplastic anaemia due to other external agents
0.000 0.476 0.524
D61.1 Drug-induced aplastic anaemia
0.000 0.476 0.524
D61.0 Constitutional aplastic anaemia
0.000 0.476 0.524
M11.2 Other chondrocalcinosis
0.000 0.477 0.523
E80.4 Gilbert's syndrome
0.000 0.477 0.523
D72.9 Disorder of white blood cells, unspecified
0.000 0.477 0.523
D72.0 Genetic anomalies of leukocytes
0.000 0.477 0.523
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.477 0.523
E07.8 Other specified disorders of thyroid
0.000 0.478 0.522
E07.1 Dyshormogenetic goitre
0.000 0.478 0.522
E07.0 Hypersecretion of calcitonin
0.000 0.478 0.522
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.478 0.521
L85.3 Xerosis cutis
0.000 0.479 0.521
L85.2 Keratosis punctata (palmaris et plantaris)
0.000 0.479 0.521
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.000 0.479 0.521
L85.0 Acquired ichthyosis
0.000 0.479 0.521
L81.9 Disorder of pigmentation, unspecified
0.000 0.479 0.521
L98.7 Excessive and redundant skin and subcutaneous tissue
0.000 0.480 0.520
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.000 0.480 0.520
L98.5 Mucinosis of skin
0.000 0.480 0.520
L98.3 Eosinophilic cellulitis [Wells]
0.000 0.480 0.520
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.000 0.480 0.520
L98.1 Factitial dermatitis
0.000 0.480 0.520
M65 Synovitis and tenosynovitis
0.000 0.482 0.518
M86-M90 Other osteopathies
0.000 0.483 0.517
H36.0 Diabetic retinopathy
0.000 0.483 0.517
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.483 0.516
L91.9 Hypertrophic disorder of skin, unspecified
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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