TreeWAS – Variant ID: Affx-89026413

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.998	0.002	0.000
I20 Angina pectoris	0.996	0.004	0.000
I25 Chronic ischaemic heart disease	0.994	0.006	0.000
I25.1 Atherosclerotic heart disease	0.990	0.010	0.000
I21 Acute myocardial infarction	0.990	0.010	0.000
E10.9 Without complications	0.000	0.014	0.986
I20.0 Unstable angina	0.980	0.020	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.020	0.980
I20.9 Angina pectoris, unspecified	0.976	0.024	0.000
I21.9 Acute myocardial infarction, unspecified	0.975	0.025	0.000
E78.0 Pure hypercholesterolaemia	0.949	0.051	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.947	0.053	0.000
E10-E14 Diabetes mellitus	0.008	0.065	0.927
I22 Subsequent myocardial infarction	0.931	0.069	0.000
E14 Unspecified diabetes mellitus	0.002	0.095	0.902
J45 Asthma	0.014	0.104	0.881
I25.8 Other forms of chronic ischaemic heart disease	0.892	0.108	0.000
E03 Other hypothyroidism	0.890	0.110	0.000
E10.3 With ophthalmic complications	0.000	0.110	0.890
I22.1 Subsequent myocardial infarction of inferior wall	0.882	0.118	0.000
E14.9 Without complications	0.000	0.122	0.878
J45.0 Predominantly allergic asthma	0.002	0.148	0.850
E00-E07 Disorders of thyroid gland	0.846	0.154	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.846	0.154	0.000
E10.1 With ketoacidosis	0.000	0.166	0.834
Chapter IV Endocrine, nutritional and metabolic diseases	0.827	0.171	0.002
E70-E90 Metabolic disorders	0.820	0.180	0.000
I23 Certain current complications following acute myocardial infarction	0.792	0.208	0.000
E10.4 With neurological complications	0.000	0.209	0.791
I25.9 Chronic ischaemic heart disease, unspecified	0.785	0.215	0.000
I25.3 Aneurysm of heart	0.777	0.223	0.000
E14.3 With ophthalmic complications	0.001	0.232	0.767
E06 Thyroiditis	0.758	0.242	0.000
E10.2 With renal complications	0.000	0.254	0.746
I22.9 Subsequent myocardial infarction of unspecified site	0.717	0.283	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.716	0.284	0.000
I25.6 Silent myocardial ischaemia	0.712	0.288	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.712	0.288	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.710	0.290	0.000
E10.5 With peripheral circulatory complications	0.000	0.294	0.706
I24 Other acute ischaemic heart diseases	0.703	0.297	0.000
E10.8 With unspecified complications	0.000	0.297	0.702
E10.7 With multiple complications	0.000	0.297	0.702
E10.6 With other specified complications	0.000	0.297	0.702
E10.0 With coma	0.000	0.297	0.702
I20.8 Other forms of angina pectoris	0.684	0.316	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.317	0.683
I25.5 Ischaemic cardiomyopathy	0.680	0.320	0.000
E12 Malnutrition-related diabetes mellitus	0.006	0.329	0.665
E13 Other specified diabetes mellitus	0.005	0.330	0.665
I21.1 Acute transmural myocardial infarction of inferior wall	0.665	0.335	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.660	0.340	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.654	0.346	0.000
E06.9 Thyroiditis, unspecified	0.651	0.349	0.000
E14.7 With multiple complications	0.002	0.351	0.647
E14.6 With other specified complications	0.002	0.351	0.647
E14.5 With peripheral circulatory complications	0.002	0.351	0.647
E14.4 With neurological complications	0.002	0.351	0.647
E14.2 Withrenal complications	0.002	0.351	0.647
E14.1 With ketoacidosis	0.002	0.351	0.647
E14.0 With coma	0.002	0.351	0.647
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.647	0.353	0.000
I23.8 Other current complications following acute myocardial infarction	0.644	0.355	0.000
J45.8 Mixed asthma	0.010	0.358	0.632
J45.1 Nonallergic asthma	0.010	0.358	0.632
I25.4 Coronary artery aneurysm	0.641	0.359	0.000
E03.5 Myxoedema coma	0.638	0.362	0.000
E03.4 Atrophy of thyroid (acquired)	0.638	0.362	0.000
E03.3 Postinfectious hypothyroidism	0.638	0.362	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.638	0.362	0.000
E03.1 Congenital hypothyroidism without goitre	0.638	0.362	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.638	0.362	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.636	0.364	0.000
# Top node	0.636	0.364	0.000
F30-F39 Mood [affective] disorders	0.633	0.367	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.632	0.367	0.000
K90 Intestinal malabsorption	0.000	0.368	0.632
Chapter V Mental and behavioural disorders	0.631	0.369	0.000
E06.3 Autoimmune thyroiditis	0.630	0.369	0.000
E78.4 Other hyperlipidaemia	0.628	0.372	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.623	0.377	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.623	0.377	0.000
I22.8 Subsequent myocardial infarction of other sites	0.621	0.379	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.621	0.379	0.000
I20.1 Angina pectoris with documented spasm	0.618	0.382	0.000
E20-E35 Disorders of other endocrine glands	0.611	0.388	0.001
T91 Sequelae of injuries of neck and trunk	0.610	0.390	0.000
E65-E68 Obesity and other hyperalimentation	0.608	0.391	0.001
Chapter IX Diseases of the circulatory system	0.609	0.391	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.606	0.393	0.000
E00 Congenital iodine-deficiency syndrome	0.606	0.393	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.606	0.393	0.000
E78.6 Lipoprotein deficiency	0.606	0.393	0.000
E78.3 Hyperchylomicronaemia	0.606	0.393	0.000
E78.1 Pure hyperglyceridaemia	0.606	0.393	0.000
F33 Recurrent depressive disorder	0.604	0.396	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.604	0.396	0.000
Q60-Q64 Congenital malformations of the urinary system	0.601	0.399	0.000
Q50-Q56 Congenital malformations of genital organs	0.599	0.401	0.000
E11.1 With ketoacidosis	0.000	0.403	0.597
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.596	0.404	0.000
E11.5 With peripheral circulatory complications	0.000	0.404	0.596
Q80-Q89 Other congenital malformations	0.593	0.407	0.000
E40-E46 Malnutrition	0.592	0.407	0.002
E84 Cystic fibrosis	0.588	0.412	0.000
E79 Disorders of purine and pyrimidine metabolism	0.588	0.412	0.000
E77 Disorders of glycoprotein metabolism	0.588	0.412	0.000
E76 Disorders of glycosaminoglycan metabolism	0.588	0.412	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.588	0.412	0.000
E72 Other disorders of amino-acid metabolism	0.588	0.412	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.588	0.412	0.000
E70 Disorders of aromatic amino-acid metabolism	0.588	0.412	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.588	0.412	0.000
E83 Disorders of mineral metabolism	0.583	0.417	0.000
E74 Other disorders of carbohydrate metabolism	0.582	0.417	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.583	0.417	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.581	0.419	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.580	0.419	0.000
F32 Depressive episode	0.575	0.425	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.575	0.425	0.000
Q25 Congenital malformations of great arteries	0.571	0.429	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.568	0.432	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.568	0.432	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.568	0.432	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.568	0.432	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.568	0.432	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.568	0.432	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.568	0.432	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.559	0.441	0.000
E73 Lactose intolerance	0.552	0.448	0.000
E14.8 With unspecified complications	0.002	0.449	0.549
Q23 Congenital malformations of aortic and mitral valves	0.551	0.449	0.000
Q54 Hypospadias	0.551	0.449	0.000
S40-S49 Injuries to the shoulder and upper arm	0.549	0.450	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.451	0.549
E21.0 Primary hyperparathyroidism	0.545	0.455	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.544	0.456	0.000
F30 Manic episode	0.544	0.456	0.000
E06.5 Other chronic thyroiditis	0.543	0.457	0.000
E06.4 Drug-induced thyroiditis	0.543	0.457	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.543	0.457	0.000
E06.1 Subacute thyroiditis	0.543	0.457	0.000
E06.0 Acute thyroiditis	0.543	0.457	0.000
E11.4 With neurological complications	0.000	0.457	0.543
F80-F89 Disorders of psychological development	0.543	0.457	0.000
F60-F69 Disorders of adult personality and behaviour	0.543	0.457	0.000
T42.4 Benzodiazepines	0.542	0.458	0.000
Q61 Cystic kidney disease	0.542	0.458	0.000
E65 Localised adiposity	0.541	0.459	0.000
E11.3 With ophthalmic complications	0.000	0.460	0.540
F33.9 Recurrent depressive disorder, unspecified	0.538	0.462	0.000
T91.3 Sequelae of injury of spinal cord	0.538	0.462	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.536	0.464	0.000
T91.1 Sequelae of fracture of spine	0.532	0.468	0.000
Q27 Other congenital malformations of peripheral vascular system	0.532	0.468	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.529	0.471	0.000
F39 Unspecified mood [affective] disorder	0.529	0.471	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.527	0.473	0.000
E85 Amyloidosis	0.526	0.473	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.527	0.473	0.000
F32.0 Mild depressive episode	0.525	0.475	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.524	0.476	0.000
E78.8 Other disorders of lipoprotein metabolism	0.523	0.477	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.523	0.477	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.522	0.478	0.000
S10-S19 Injuries to the neck	0.513	0.487	0.000
E83.5 Disorders of calcium metabolism	0.512	0.488	0.000
T79-T79 Certain early complications of trauma	0.511	0.489	0.000
E07 Other disorders of thyroid	0.511	0.489	0.000
F31 Bipolar affective disorder	0.509	0.491	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.508	0.492	0.000
Q25.1 Coarctation of aorta	0.506	0.494	0.000
Chapter XX External causes of morbidity and mortality	0.505	0.495	0.000
I24.1 Dressler's syndrome	0.504	0.496	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.504	0.496	0.000
Q23.1 Congenital insufficiency of aortic valve	0.501	0.499	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.499	0.501	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.498	0.502	0.000
E80.4 Gilbert's syndrome	0.498	0.502	0.000
F32.1 Moderate depressive episode	0.497	0.503	0.000
E50-E64 Other nutritional deficiencies	0.494	0.504	0.002
T20-T25 Burns and corrosions of external body surface, specified by site	0.495	0.505	0.000
E78.5 Hyperlipidaemia, unspecified	0.494	0.506	0.000
E11.7 With multiple complications	0.000	0.510	0.490
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.489	0.511	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.486	0.514	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.485	0.515	0.000
T36 Poisoning by systemic antibiotics	0.483	0.517	0.000
T93 Sequelae of injuries of lower limb	0.483	0.517	0.000
Q25.4 Other congenital malformations of aorta	0.483	0.517	0.000
F84 Pervasive developmental disorders	0.483	0.517	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.483	0.517	0.000
Q63 Other congenital malformations of kidney	0.482	0.518	0.000
E11.8 With unspecified complications	0.000	0.518	0.482
E12.9 Without complications	0.004	0.519	0.477
E12.8 With unspecified complications	0.004	0.519	0.477
E12.7 With multiple complications	0.004	0.519	0.477
E12.6 With other specified complications	0.004	0.519	0.477
E12.5 With peripheral circulatory complications	0.004	0.519	0.477
E12.4 With neurological complications	0.004	0.519	0.477
E12.3 With ophthalmic complications	0.004	0.519	0.477
E12.2 With renal complications	0.004	0.519	0.477
E12.1 With ketoacidosis	0.004	0.519	0.477
E12.0 With coma	0.004	0.519	0.477
T91.8 Sequelae of other specified injuries of neck and trunk	0.481	0.519	0.000
E13.8 With unspecified complications	0.004	0.519	0.477
E13.7 With multiple complications	0.004	0.519	0.477
E13.6 With other specified complications	0.004	0.519	0.477
E13.5 With peripheral circulatory complications	0.004	0.519	0.477
E13.4 With neurological complications	0.004	0.519	0.477
E13.3 With ophthalmic complications	0.004	0.519	0.477
E13.2 With renal complications	0.004	0.519	0.477
E13.1 With ketoacidosis	0.004	0.519	0.477
E13.0 With coma	0.004	0.519	0.477
T90 Sequelae of injuries of head	0.480	0.520	0.000
E13.9 Without complications	0.003	0.520	0.477
E78.2 Mixed hyperlipidaemia	0.480	0.520	0.000
E11.6 With other specified complications	0.000	0.520	0.479
Q64 Other congenital malformations of urinary system	0.479	0.521	0.000
F02 Dementia in other diseases classified elsewhere	0.479	0.521	0.000
Q54.1 Hypospadias, penile	0.478	0.522	0.000
E26 Hyperaldosteronism	0.476	0.523	0.001
T42.1 Iminostilbenes	0.476	0.524	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.474	0.524	0.002
F05.9 Delirium, unspecified	0.475	0.525	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.475	0.525	0.000
F60 Specific personality disorders	0.474	0.526	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.474	0.526	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.473	0.527	0.000
E89.4 Postprocedural ovarian failure	0.473	0.527	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.473	0.527	0.000
T00-T07 Injuries involving multiple body regions	0.473	0.527	0.000
F70-F79 Mental retardation	0.473	0.527	0.000
T95 Sequelae of burns, corrosions and frostbite	0.471	0.529	0.000
E04 Other non-toxic goitre	0.471	0.529	0.000
I21.4 Acute subendocardial myocardial infarction	0.471	0.529	0.000
Q83 Congenital malformations of breast	0.470	0.530	0.000
T43.2 Other and unspecified antidepressants	0.468	0.532	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.467	0.533	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.467	0.533	0.000
Q00-Q07 Congenital malformations of the nervous system	0.467	0.533	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.464	0.536	0.000
Q35-Q37 Cleft lip and cleft palate	0.464	0.536	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.464	0.536	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.462	0.538	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.459	0.541	0.000
S42 Fracture of shoulder and upper arm	0.458	0.542	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.457	0.543	0.000
T59 Toxic effect of other gases, fumes and vapours	0.456	0.544	0.000
Q87.4 Marfan's syndrome	0.456	0.544	0.000
T33-T35 Frostbite	0.456	0.544	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.456	0.544	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.456	0.544	0.000
F38 Other mood [affective] disorders	0.454	0.546	0.000
F34 Persistent mood [affective] disorders	0.454	0.546	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.453	0.546	0.000
E80.6 Other disorders of bilirubin metabolism	0.453	0.546	0.000
E80.5 Crigler-Najjar syndrome	0.453	0.546	0.000
E80.3 Defects of catalase and peroxydase	0.453	0.546	0.000
E80.2 Other porphyria	0.453	0.546	0.000
E80.1 Porphyria cutanea tarda	0.453	0.546	0.000
E80.0 Hereditary erythropoietic porphyria	0.453	0.546	0.000
K90.8 Other intestinal malabsorption	0.000	0.547	0.453
K90.3 Pancreatic steatorrhoea	0.000	0.547	0.453
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.547	0.453
K90.1 Tropical sprue	0.000	0.547	0.453
F30.9 Manic episode, unspecified	0.453	0.547	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.453	0.547	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.452	0.548	0.000
Q61.9 Cystic kidney disease, unspecified	0.451	0.549	0.000
S50-S59 Injuries to the elbow and forearm	0.450	0.550	0.000
E83.4 Disorders of magnesium metabolism	0.449	0.551	0.000
Q54.9 Hypospadias, unspecified	0.449	0.551	0.000
Q89 Other congenital malformations, not elsewhere classified	0.448	0.552	0.000
T66-T78 Other and unspecified effects of external causes	0.448	0.552	0.000
F00 Dementia in Alzheimer's disease	0.448	0.552	0.000
E89.2 Postprocedural hypoparathyroidism	0.447	0.553	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.447	0.553	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.447	0.553	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.447	0.553	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.447	0.553	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.446	0.553	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.446	0.553	0.000
E21.3 Hyperparathyroidism, unspecified	0.446	0.554	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.554	0.445
Q26 Congenital malformations of great veins	0.445	0.555	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.445	0.555	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.445	0.555	0.000
F05.8 Other delirium	0.445	0.555	0.000
V10-V19 Pedal cyclist injured in transport accident	0.444	0.556	0.000
F31.9 Bipolar affective disorder, unspecified	0.443	0.557	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.443	0.557	0.000
E03.8 Other specified hypothyroidism	0.441	0.558	0.001
F84.5 Asperger's syndrome	0.440	0.560	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.440	0.560	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.438	0.561	0.001
E32 Diseases of thymus	0.438	0.561	0.001
E31 Polyglandular dysfunction	0.438	0.561	0.001
E30 Disorders of puberty, not elsewhere classified	0.438	0.561	0.001
E25 Adrenogenital disorders	0.438	0.561	0.001
E20 Hypoparathyroidism	0.438	0.561	0.001
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.438	0.562	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.438	0.562	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.438	0.562	0.000
E67 Other hyperalimentation	0.436	0.563	0.001
E68 Sequelae of hyperalimentation	0.436	0.563	0.001
I00-I02 Acute rheumatic fever	0.437	0.563	0.000
Q54.0 Hypospadias, balanic	0.437	0.563	0.000
F30.0 Hypomania	0.436	0.564	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.435	0.565	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.435	0.565	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.435	0.565	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.435	0.565	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.435	0.565	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.435	0.565	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.435	0.565	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.435	0.565	0.000
E34 Other endocrine disorders	0.434	0.565	0.001
T43.0 Tricyclic and tetracyclic antidepressants	0.435	0.565	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.434	0.566	0.000
F33.8 Other recurrent depressive disorders	0.433	0.567	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.433	0.567	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.433	0.567	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.433	0.567	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.432	0.568	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.431	0.568	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.431	0.569	0.000
S20-S29 Injuries to the thorax	0.431	0.569	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.431	0.569	0.000
Q61.0 Congenital single renal cyst	0.430	0.570	0.000
E28 Ovarian dysfunction	0.429	0.570	0.001
Q56 Indeterminate sex and pseudohermaphroditism	0.429	0.570	0.000
Q55 Other congenital malformations of male genital organs	0.429	0.570	0.000
Q52 Other congenital malformations of female genitalia	0.429	0.570	0.000
S40 Superficial injury of shoulder and upper arm	0.429	0.571	0.000
Q24 Other congenital malformations of heart	0.429	0.571	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.427	0.572	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.427	0.572	0.000
T42.3 Barbiturates	0.427	0.572	0.000
T42.2 Succinimides and oxazolidinediones	0.427	0.572	0.000
T42.0 Hydantoin derivatives	0.427	0.572	0.000
Q61.2 Polycystic kidney, adult type	0.427	0.573	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.426	0.574	0.000
E83.3 Disorders of phosphorus metabolism	0.426	0.574	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.425	0.574	0.000
Q84 Other congenital malformations of integument	0.425	0.574	0.000
Q81 Epidermolysis bullosa	0.425	0.574	0.000
Q80 Congenital ichthyosis	0.425	0.574	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.424	0.575	0.001
E45 Retarded development following protein-energy malnutrition	0.424	0.575	0.001
E43 Unspecified severe protein-energy malnutrition	0.424	0.575	0.001
E42 Marasmic kwashiorkor	0.424	0.575	0.001
E41 Nutritional marasmus	0.424	0.575	0.001
E40 Kwashiorkor	0.424	0.575	0.001
S41 Open wound of shoulder and upper arm	0.425	0.575	0.000
T17 Foreign body in respiratory tract	0.425	0.575	0.000
E46 Unspecified protein-energy malnutrition	0.423	0.576	0.001
Q51 Congenital malformations of uterus and cervix	0.424	0.576	0.000
Y57 Other and unspecified drugs and medicaments	0.423	0.577	0.000
J40-J47 Chronic lower respiratory diseases	0.376	0.578	0.046
F32.8 Other depressive episodes	0.422	0.578	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.422	0.578	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.421	0.578	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.421	0.578	0.000
E70.3 Albinism	0.421	0.578	0.000
E70.2 Disorders of tyrosine metabolism	0.421	0.578	0.000
E70.1 Other hyperphenylalaninaemias	0.421	0.578	0.000
E70.0 Classical phenylketonuria	0.421	0.578	0.000
E71.3 Disorders of fatty-acid metabolism	0.421	0.578	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.421	0.578	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.421	0.578	0.000
E71.0 Maple-syrup-urine disease	0.421	0.578	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.421	0.578	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.421	0.578	0.000
E72.5 Disorders of glycine metabolism	0.421	0.578	0.000
E72.4 Disorders of ornithine metabolism	0.421	0.578	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.421	0.578	0.000
E72.2 Disorders of urea cycle metabolism	0.421	0.578	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.421	0.578	0.000
E72.0 Disorders of amino-acid transport	0.421	0.578	0.000
E75.6 Lipid storage disorder, unspecified	0.421	0.578	0.000
E75.5 Other lipid storage disorders	0.421	0.578	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.421	0.578	0.000
E75.3 Sphingolipidosis, unspecified	0.421	0.578	0.000
E75.2 Other sphingolipidosis	0.421	0.578	0.000
E75.1 Other gangliosidosis	0.421	0.578	0.000
E75.0 GM2 gangliosidosis	0.421	0.578	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.421	0.578	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.421	0.578	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.421	0.578	0.000
E76.2 Other mucopolysaccharidoses	0.421	0.578	0.000
E76.1 Mucopolysaccharidosis, type II	0.421	0.578	0.000
E76.0 Mucopolysaccharidosis, type I	0.421	0.578	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.421	0.578	0.000
E77.8 Other disorders of glycoprotein metabolism	0.421	0.578	0.000
E77.1 Defects in glycoprotein degradation	0.421	0.578	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.421	0.578	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.421	0.578	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.421	0.578	0.000
E79.1 Lesch-Nyhan syndrome	0.421	0.578	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.421	0.578	0.000
E84.9 Cystic fibrosis, unspecified	0.421	0.578	0.000
E84.8 Cystic fibrosis with other manifestations	0.421	0.578	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.421	0.578	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.421	0.578	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.422	0.578	0.000
E88 Other metabolic disorders	0.420	0.579	0.001
Chapter X Diseases of the respiratory system	0.420	0.579	0.001
F81 Specific developmental disorders of scholastic skills	0.420	0.580	0.000
Q85 Phakomatoses, not elsewhere classified	0.420	0.580	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.418	0.582	0.000
E83.8 Other disorders of mineral metabolism	0.418	0.582	0.000
E83.2 Disorders of zinc metabolism	0.418	0.582	0.000
E83.0 Disorders of copper metabolism	0.418	0.582	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.418	0.582	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.418	0.582	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.418	0.582	0.000
E74.2 Disorders of galactose metabolism	0.418	0.582	0.000
E74.1 Disorders of fructose metabolism	0.418	0.582	0.000
E74.0 Glycogen storage disease	0.418	0.582	0.000
Q53 Undescended testicle	0.418	0.582	0.000
W50-W64 Exposure to animate mechanical forces	0.417	0.583	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.417	0.583	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.416	0.583	0.000
E21.4 Other specified disorders of parathyroid gland	0.416	0.583	0.000
E21.2 Other hyperparathyroidism	0.416	0.583	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.416	0.584	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.416	0.584	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.416	0.584	0.000
E89.5 Postprocedural testicular hypofunction	0.416	0.584	0.000
E89.1 Postprocedural hypoinsulinaemia	0.416	0.584	0.000
E11.2 With renal complications	0.000	0.584	0.415
J30-J39 Other diseases of upper respiratory tract	0.415	0.584	0.000
I24.8 Other forms of acute ischaemic heart disease	0.415	0.585	0.000
Q43 Other congenital malformations of intestine	0.414	0.585	0.000
S10 Superficial injury of neck	0.414	0.586	0.000
Q28 Other congenital malformations of circulatory system	0.414	0.586	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.412	0.587	0.000
X10-X19 Contact with heat and hot substances	0.412	0.587	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.412	0.587	0.000
F09 Unspecified organic or symptomatic mental disorder	0.412	0.587	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.412	0.587	0.000
Y57.9 Drug or medicament, unspecified	0.412	0.588	0.000
Q61.3 Polycystic kidney, unspecified	0.411	0.589	0.000
T38.1 Thyroid hormones and substitutes	0.410	0.589	0.000
J32 Chronic sinusitis	0.410	0.590	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.410	0.590	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.410	0.590	0.000
Q25.8 Other congenital malformations of great arteries	0.410	0.590	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.410	0.590	0.000
Q25.6 Stenosis of pulmonary artery	0.410	0.590	0.000
Q25.5 Atresia of pulmonary artery	0.410	0.590	0.000
Q25.3 Stenosis of aorta	0.410	0.590	0.000
Q25.2 Atresia of aorta	0.410	0.590	0.000
Q25.0 Patent ductus arteriosus	0.410	0.590	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.409	0.590	0.000
T98 Sequelae of other and unspecified effects of external causes	0.409	0.590	0.000
S19 Other and unspecified injuries of neck	0.409	0.591	0.000
T59.8 Other specified gases, fumes and vapours	0.409	0.591	0.000
J35 Chronic diseases of tonsils and adenoids	0.409	0.591	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.406	0.594	0.000
J32.9 Chronic sinusitis, unspecified	0.406	0.594	0.000
S37 Injury of urinary and pelvic organs	0.406	0.594	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.406	0.594	0.000
S42.0 Fracture of clavicle	0.403	0.597	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.403	0.597	0.000
F69 Unspecified disorder of adult personality and behaviour	0.402	0.598	0.000
E61 Deficiency of other nutrient elements	0.401	0.598	0.001
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.402	0.598	0.000
T31 Burns classified according to extent of body surface involved	0.401	0.599	0.000
S11 Open wound of neck	0.401	0.599	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.400	0.600	0.000
I05-I09 Chronic rheumatic heart diseases	0.398	0.602	0.000
S42.1 Fracture of scapula	0.398	0.602	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.396	0.604	0.000
Q23.0 Congenital stenosis of aortic valve	0.396	0.604	0.000
E73.8 Other lactose intolerance	0.396	0.604	0.000
E73.1 Secondary lactase deficiency	0.396	0.604	0.000
E73.0 Congenital lactase deficiency	0.396	0.604	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.396	0.604	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.395	0.604	0.000
F60.3 Emotionally unstable personality disorder	0.395	0.605	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.395	0.605	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.395	0.605	0.000
Q23.4 Hypoplastic left heart syndrome	0.395	0.605	0.000
Q23.3 Congenital mitral insufficiency	0.395	0.605	0.000
Q23.2 Congenital mitral stenosis	0.395	0.605	0.000
Q54.8 Other hypospadias	0.395	0.605	0.000
Q54.4 Congenital chordee	0.395	0.605	0.000
Q54.3 Hypospadias, perineal	0.395	0.605	0.000
Q54.2 Hypospadias, penoscrotal	0.395	0.605	0.000
S48 Traumatic amputation of shoulder and upper arm	0.394	0.606	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.394	0.606	0.000
S44 Injury of nerves at shoulder and upper arm level	0.394	0.606	0.000
S47 Crushing injury of shoulder and upper arm	0.394	0.606	0.000
Q82 Other congenital malformations of skin	0.394	0.606	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.392	0.607	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations