TreeWAS – Variant ID: rs10015037

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D35.1 Parathyroid gland	0.044	0.956	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.985	0.015
E16.2 Hypoglycaemia, unspecified	0.012	0.988	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.990	0.010
M19.01 Primary arthrosis of other joints (Shoulder region)	0.008	0.992	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.993	0.007
Z50.1 Other physical therapy	0.007	0.993	0.000
E16 Other disorders of pancreatic internal secretion	0.007	0.993	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.007	0.993	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.006	0.994	0.000
E27.9 Disorder of adrenal gland, unspecified	0.006	0.994	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.006	0.994	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.006	0.994	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.006	0.994	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.994	0.006
T92.1 Sequelae of fracture of arm	0.006	0.994	0.000
E27.1 Primary adrenocortical insufficiency	0.006	0.994	0.000
M19.0 Primary arthrosis of other joints	0.006	0.994	0.000
E16.1 Other hypoglycaemia	0.005	0.995	0.000
K60.1 Chronic anal fissure	0.000	0.995	0.005
E27.2 Addisonian crisis	0.005	0.995	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.005	0.995	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.005	0.995	0.000
E16.4 Abnormal secretion of gastrin	0.005	0.995	0.000
E16.3 Increased secretion of glucagon	0.005	0.995	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.005	0.995	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.005	0.995	0.000
E27.8 Other specified disorders of adrenal gland	0.005	0.995	0.000
D35.9 Endocrine gland, unspecified	0.005	0.995	0.000
D35.8 Pluriglandular involvement	0.005	0.995	0.000
D35.7 Other specified endocrine glands	0.005	0.995	0.000
D35.6 Aortic body and other paraganglia	0.005	0.995	0.000
D35.5 Carotid body	0.005	0.995	0.000
D35.4 Pineal gland	0.005	0.995	0.000
D35.3 Craniopharyngeal duct	0.005	0.995	0.000
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.005	0.995	0.000
D06.9 Cervix, unspecified	0.005	0.995	0.000
G45.3 Amaurosis fugax	0.005	0.995	0.000
D69.6 Thrombocytopenia, unspecified	0.005	0.995	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.005	0.995	0.000
M19.08 Primary arthrosis of other joints (Other)	0.005	0.995	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.004	0.996	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.004	0.996	0.000
H36.0 Diabetic retinopathy	0.000	0.996	0.004
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.996	0.004
D69 Purpura and other haemorrhagic conditions	0.004	0.996	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.004	0.996	0.000
D69.5 Secondary thrombocytopenia	0.004	0.996	0.000
K60 Fissure and fistula of anal and rectal regions	0.000	0.996	0.004
G45.0 Vertebro-basilar artery syndrome	0.004	0.996	0.000
S42.30 Fracture of shaft of humerus (closed)	0.004	0.996	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.004	0.996	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.004	0.996	0.000
Y83.5 Amputation of limb(s)	0.004	0.996	0.000
D68 Other coagulation defects	0.004	0.996	0.000
D68.8 Other specified coagulation defects	0.004	0.996	0.000
K60.0 Acute anal fissure	0.000	0.996	0.004
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.004	0.996	0.000
S42.10 Fracture of scapula (closed)	0.004	0.996	0.000
K60.4 Rectal fistula	0.000	0.996	0.004
D69.3 Idiopathic thrombocytopenic purpura	0.003	0.996	0.000
D66 Hereditary factor VIII deficiency	0.003	0.997	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.003	0.997	0.000
K60.5 Anorectal fistula	0.000	0.997	0.003
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
D69.1 Qualitative platelet defects	0.003	0.997	0.000
D35.2 Pituitary gland	0.003	0.997	0.000
D68.0 Von Willebrand's disease	0.003	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.003	0.997	0.000
N84.1 Polyp of cervix uteri	0.000	0.997	0.003
K60.2 Anal fissure, unspecified	0.000	0.997	0.003
D68.1 Hereditary factor XI deficiency	0.003	0.997	0.000
S42.3 Fracture of shaft of humerus	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.997	0.003
M19.09 Primary arthrosis of other joints (Site unspecified)	0.003	0.997	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
K60.3 Anal fistula	0.000	0.997	0.003
D68.4 Acquired coagulation factor deficiency	0.003	0.997	0.000
D69.0 Allergic purpura	0.003	0.997	0.000
S42.1 Fracture of scapula	0.003	0.997	0.000
J38.2 Nodules of vocal cords	0.000	0.997	0.003
F10.3 Withdrawal state	0.000	0.997	0.003
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.003
D67 Hereditary factor IX deficiency	0.003	0.997	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
R06.2 Wheezing	0.003	0.997	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.003	0.997	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.003	0.997	0.000
S02.30 Fracture of orbital floor (closed)	0.000	0.997	0.003
I42.0 Dilated cardiomyopathy	0.003	0.997	0.000
D35.0 Adrenal gland	0.002	0.997	0.000
S02 Fracture of skull and facial bones	0.000	0.997	0.003
S42.31 Fracture of shaft of humerus (open)	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.000	0.997	0.003
M23.30 Other meniscus derangements (Multiple sites)	0.003	0.997	0.000
Z74.0 Reduced mobility	0.003	0.997	0.000
D68.9 Coagulation defect, unspecified	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.997	0.003
S42 Fracture of shoulder and upper arm	0.003	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.997	0.003
S02.8 Fractures of other skull and facial bones	0.000	0.997	0.002
I74 Arterial embolism and thrombosis	0.000	0.997	0.003
E87.2 Acidosis	0.003	0.997	0.000
E87.5 Hyperkalaemia	0.000	0.998	0.002
E15 Nondiabetic hypoglycaemic coma	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
S42.11 Fracture of scapula (open)	0.002	0.998	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
A41.9 Septicaemia, unspecified	0.002	0.998	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
N05.9 Unspecified	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.002	0.998	0.000
H02.3 Blepharochalasis	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
S42.7 Multiple fractures of clavicle, scapula and humerus	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.002	0.998	0.000
V23.4 Driver injured in traffic accident	0.002	0.998	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.002	0.998	0.000
D06 Carcinoma in situ of cervix uteri	0.002	0.998	0.000
S42.20 Fracture of upper end of humerus (closed)	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.000	0.998	0.002
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
H93.1 Tinnitus	0.000	0.998	0.002
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.002
S02.7 Multiple fractures involving skull and facial bones	0.000	0.998	0.002
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.998	0.002
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.002
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.002	0.998	0.000
S02.5 Fracture of tooth	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.998	0.002
Z74.1 Need for assistance with personal care	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.000	0.998	0.002
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.002	0.998	0.000
S02.0 Fracture of vault of skull	0.000	0.998	0.002
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.998	0.002
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
I35 Nonrheumatic aortic valve disorders	0.000	0.998	0.002
K90.0 Coeliac disease	0.000	0.998	0.002
S42.21 Fracture of upper end of humerus (open)	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
M23.5 Chronic instability of knee	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.002
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.002
S42.9 Fracture of shoulder girdle, part unspecified	0.002	0.998	0.000
D06.0 Endocervix	0.002	0.998	0.000
Z72.2 Drug use	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.002	0.998	0.000
G45.4 Transient global amnesia	0.002	0.998	0.000
D75.0 Familial erythrocytosis	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.002
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.002	0.998	0.000
D06.7 Other parts of cervix	0.002	0.998	0.000
D06.1 Exocervix	0.002	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
H33.4 Traction detachment of retina	0.000	0.998	0.002
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
Z74 Problems related to care-provider dependency	0.002	0.998	0.000
H33.5 Other retinal detachments	0.000	0.998	0.002
T92.8 Sequelae of other specified injuries of upper limb	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.002
S02.6 Fracture of mandible	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.998	0.002
E20 Hypoparathyroidism	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.000	0.998	0.002
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.998	0.002
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.998	0.002
H33.1 Retinoschisis and retinal cysts	0.000	0.998	0.002
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.002
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.998	0.002
H33 Retinal detachments and breaks	0.000	0.998	0.002
E25 Adrenogenital disorders	0.002	0.998	0.000
X41.9 Unspecified place	0.002	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.001
M23.3 Other meniscus derangements	0.002	0.998	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.002	0.998	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.002	0.998	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.002	0.998	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.002	0.998	0.000
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.001	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.002	0.998	0.000
O43.8 Other placental disorders	0.002	0.998	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.998	0.002
C02.1 Border of tongue	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Z74.8 Other problems related to care-provider dependency	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.998	0.001
D29.1 Prostate	0.002	0.998	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.001
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.998	0.001
S42.4 Fracture of lower end of humerus	0.001	0.998	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.000	0.998	0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
S02.1 Fracture of base of skull	0.000	0.998	0.001
S64.3 Injury of digital nerve of thumb	0.000	0.998	0.002
Z74.3 Need for continuous supervision	0.001	0.998	0.000
E21.2 Other hyperparathyroidism	0.001	0.998	0.000
J38.7 Other diseases of larynx	0.000	0.998	0.002
T92.0 Sequelae of open wound of upper limb	0.001	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.002
M94.26 Chondromalacia (Lower leg)	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.000	0.998	0.001
E20.8 Other hypoparathyroidism	0.001	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.001	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.001	0.998	0.000
H33.2 Serous retinal detachment	0.000	0.998	0.002
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
E24 Cushing's syndrome	0.001	0.998	0.000
Q61 Cystic kidney disease	0.000	0.998	0.002
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.002
E21.5 Disorder of parathyroid gland, unspecified	0.001	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.998	0.001
C92.0 Acute myeloid leukaemia	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.001	0.998	0.000
E25.8 Other adrenogenital disorders	0.001	0.998	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.002	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.998	0.001
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.001	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.001	0.998	0.000
E30.8 Other disorders of puberty	0.001	0.998	0.000
E30.1 Precocious puberty	0.001	0.998	0.000
E30.0 Delayed puberty	0.001	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.001	0.998	0.000
E31.8 Other polyglandular dysfunction	0.001	0.998	0.000
E31.1 Polyglandular hyperfunction	0.001	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.001	0.998	0.000
E32.9 Disease of thymus, unspecified	0.001	0.998	0.000
E32.8 Other diseases of thymus	0.001	0.998	0.000
E32.1 Abscess of thymus	0.001	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.001	0.998	0.000
E34.8 Other specified endocrine disorders	0.001	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.001	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.001	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.001	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
I35.0 Aortic (valve) stenosis	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.001
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.001	0.998	0.000
S40 Superficial injury of shoulder and upper arm	0.001	0.998	0.000
M23.37 Other meniscus derangements-Capsular lig	0.001	0.998	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.001	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.001	0.998	0.000
E26 Hyperaldosteronism	0.001	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.999	0.001
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.001	0.999	0.000
J38.4 Oedema of larynx	0.000	0.999	0.001
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.999	0.001
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.999	0.001
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.001	0.999	0.000
F22.0 Delusional disorder	0.001	0.999	0.000
Z76.3 Healthy person accompanying sick person	0.001	0.999	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.999	0.001
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.999	0.000
S42.41 Fracture of lower end of humerus (open)	0.001	0.999	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.001	0.999	0.000
E34.0 Carcinoid syndrome	0.001	0.999	0.000
H33.3 Retinal breaks without detachment	0.000	0.999	0.001
K76.9 Liver disease, unspecified	0.000	0.999	0.001
S40.8 Other superficial injuries of shoulder and upper arm	0.001	0.999	0.000
S72.4 Fracture of lower end of femur	0.001	0.999	0.000
E34.5 Androgen resistance syndrome	0.001	0.999	0.000
E34.4 Constitutional tall stature	0.001	0.999	0.000
E34.3 Short stature, not elsewhere classified	0.001	0.999	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.999	0.000
E34.1 Other hypersecretion of intestinal hormones	0.001	0.999	0.000
F45.8 Other somatoform disorders	0.001	0.999	0.000
H02.6 Xanthelasma of eyelid	0.001	0.999	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.001	0.999	0.000
I35.8 Other aortic valve disorders	0.000	0.999	0.001
I71.0 Dissection of aorta [any part]	0.000	0.999	0.001
M47.99 Spondylosis, unspecified (Site unspecified)	0.001	0.999	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.999	0.001
E24.8 Other Cushing's syndrome	0.001	0.999	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.001	0.999	0.000
E24.3 Ectopic ACTH syndrome	0.001	0.999	0.000
E24.2 Drug-induced Cushing's syndrome	0.001	0.999	0.000
E24.1 Nelson's syndrome	0.001	0.999	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.999	0.001
S42.0 Fracture of clavicle	0.001	0.999	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.999	0.001
S64.8 Injury of other nerves at wrist and hand level	0.000	0.999	0.001
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.999	0.001
D72 Other disorders of white blood cells	0.001	0.999	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.999	0.001
I77.6 Arteritis, unspecified	0.000	0.999	0.001
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.999	0.001
Q61.8 Other cystic kidney diseases	0.000	0.999	0.001
Q61.4 Renal dysplasia	0.000	0.999	0.001
Q61.1 Polycystic kidney, infantile type	0.000	0.999	0.001
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.001	0.999	0.000
E29 Testicular dysfunction	0.001	0.999	0.000
D07.1 Vulva	0.000	0.999	0.001
N05.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N05.6 Dense deposit disease	0.001	0.999	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N05.0 Minor glomerular abnormality	0.001	0.999	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
S72.41 Fracture of lower end of femur (open)	0.001	0.999	0.000
E26.9 Hyperaldosteronism, unspecified	0.001	0.999	0.000
E26.8 Other hyperaldosteronism	0.001	0.999	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.999	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.999	0.001
S40.7 Multiple superficial injuries of shoulder and upper arm	0.001	0.999	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.999	0.001
F52.2 Failure of genital response	0.001	0.999	0.000
N83.1 Corpus luteum cyst	0.000	0.999	0.001
V23.9 Unspecified motorcycle rider injured in traffic accident	0.001	0.999	0.000
V23.5 Passenger injured in traffic accident	0.001	0.999	0.000
V23.3 Person injured while boarding or alighting	0.001	0.999	0.000
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.001	0.999	0.000
V23.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
V23.0 Driver injured in nontraffic accident	0.001	0.999	0.000
E28 Ovarian dysfunction	0.001	0.999	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
D72.1 Eosinophilia	0.001	0.999	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
S02.11 Fracture of base of skull (open)	0.000	0.999	0.001
S52.80 Fracture of other parts of forearm (closed)	0.000	0.999	0.001
E24.9 Cushing's syndrome, unspecified	0.001	0.999	0.000
N05.8 Other	0.001	0.999	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.999	0.001
M84.06 Malunion of fracture (Lower leg)	0.000	0.999	0.001
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.999	0.001
N05.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.001	0.999	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.999	0.001
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.999	0.001
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.999	0.001
S42.01 Fracture of clavicle (open)	0.001	0.999	0.000
D72.9 Disorder of white blood cells, unspecified	0.001	0.999	0.000
D72.0 Genetic anomalies of leukocytes	0.001	0.999	0.000
E24.0 Pituitary-dependent Cushing's disease	0.001	0.999	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.999	0.001
Q61.9 Cystic kidney disease, unspecified	0.000	0.999	0.001
V27.4 Driver injured in traffic accident	0.001	0.999	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.001	0.999	0.000
C26.0 Intestinal tract, part unspecified	0.001	0.999	0.000
E29.9 Testicular dysfunction, unspecified	0.001	0.999	0.000
E29.8 Other testicular dysfunction	0.001	0.999	0.000
E29.0 Testicular hyperfunction	0.001	0.999	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.001	0.999	0.001
D75.8 Other specified diseases of blood and blood-forming organs	0.001	0.999	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.999	0.001
K90.9 Intestinal malabsorption, unspecified	0.000	0.999	0.001
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.999	0.001
I70 Atherosclerosis	0.000	0.999	0.001
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.999	0.001
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.001	0.999	0.000
E28.9 Ovarian dysfunction, unspecified	0.001	0.999	0.000
E28.8 Other ovarian dysfunction	0.001	0.999	0.000
E28.1 Androgen excess	0.001	0.999	0.000
E28.0 Oestrogen excess	0.001	0.999	0.000
M93.9 Osteochondropathy, unspecified	0.001	0.999	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.001	0.999	0.000
H60.8 Other otitis externa	0.001	0.999	0.000
M77.9 Enthesopathy, unspecified	0.001	0.999	0.000
S40.0 Contusion of shoulder and upper arm	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
M19 Other arthrosis	0.001	0.999	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.001	0.999	0.000
M77.94 Enthesopathy, unspecified (Hand)	0.001	0.999	0.000
M84.02 Malunion of fracture (Upper arm)	0.000	0.999	0.001
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.001	0.999	0.000
S62.31 Fracture of other metacarpal bone (open)	0.001	0.999	0.000
E21.0 Primary hyperparathyroidism	0.001	0.999	0.000
H52.0 Hypermetropia	0.001	0.999	0.000
I97.1 Other functional disturbances following cardiac surgery	0.001	0.999	0.000
S70.0 Contusion of hip	0.000	0.999	0.001
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.000	0.999	0.001
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.001	0.999	0.000
G61.0 Guillain-Barre syndrome	0.001	0.999	0.000
I70.8 Atherosclerosis of other arteries	0.000	0.999	0.001
R09.2 Respiratory arrest	0.000	0.999	0.001
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.999	0.001
M77.99 Enthesopathy, unspecified (Site unspecified)	0.001	0.999	0.000
M77.98 Enthesopathy, unspecified (Other)	0.001	0.999	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.001	0.999	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.001	0.999	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.001	0.999	0.000
I70.0 Atherosclerosis of aorta	0.000	0.999	0.001
M19.2 Other secondary arthrosis	0.001	0.999	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.999	0.001
Z59.1 Inadequate housing	0.001	0.999	0.000
G20 Parkinson's disease	0.001	0.999	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.999	0.001
M84.04 Malunion of fracture (Hand)	0.000	0.999	0.001
S02.60 Fracture of mandible (closed)	0.000	0.999	0.001
M19.8 Other specified arthrosis	0.001	0.999	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.000	0.999	0.001
N75.0 Cyst of Bartholin's gland	0.000	0.999	0.001
T88.4 Failed or difficult intubation	0.001	0.999	0.000
Z00.5 Examination of potential donor of organ and tissue	0.001	0.999	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.999	0.001
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.999	0.001
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.001	0.999	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.999	0.001
E26.0 Primary hyperaldosteronism	0.001	0.999	0.000
E28.3 Primary ovarian failure	0.001	0.999	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.999	0.001
I70.1 Atherosclerosis of renal artery	0.000	0.999	0.001
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.999	0.001
M19.1 Posttraumatic arthrosis of other joints	0.001	0.999	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.000	0.999	0.001
M96.5 Postradiation scoliosis	0.000	0.999	0.001
M96.4 Postsurgical lordosis	0.000	0.999	0.001
M96.3 Postlaminectomy kyphosis	0.000	0.999	0.001
M96.2 Postradiation kyphosis	0.000	0.999	0.001
N70.1 Chronic salpingitis and oophoritis	0.000	0.999	0.001
T86.1 Kidney transplant failure and rejection	0.001	0.999	0.000
T91.3 Sequelae of injury of spinal cord	0.000	0.999	0.001
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.999	0.001
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.999	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.001	0.999	0.000
M19.28 Other secondary arthrosis (Other)	0.001	0.999	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.001	0.999	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.001	0.999	0.000
M19.24 Other secondary arthrosis (Hand)	0.001	0.999	0.000
M19.23 Other secondary arthrosis (Forearm)	0.001	0.999	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.001	0.999	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.001	0.999	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.001	0.999	0.000
C44.5 Skin of trunk	0.001	0.999	0.000
J38.6 Stenosis of larynx	0.000	0.999	0.001
M84.0 Malunion of fracture	0.000	0.999	0.001
M94.2 Chondromalacia	0.001	0.999	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.999	0.001
O26.2 Pregnancy care of habitual aborter	0.000	0.999	0.001
R77.9 Abnormality of plasma protein, unspecified	0.001	0.999	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.999	0.001
M19.89 Other specified arthrosis (Site unspecified)	0.001	0.999	0.000
M19.88 Other specified arthrosis (Other)	0.001	0.999	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations