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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1002925
log Bayes Factor = 52.9041
Chromosome 6   position 28,801,383  (GRCh37) Explore rs1002925 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.005 0.995
E16.2 Hypoglycaemia, unspecified
0.000 0.007 0.993
E16 Other disorders of pancreatic internal secretion
0.000 0.007 0.993
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.007 0.993
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.008 0.992
E00-E07 Disorders of thyroid gland
0.000 0.010 0.990
E10.2 With renal complications
0.000 0.048 0.952
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.051 0.949
E10.1 With ketoacidosis
0.000 0.087 0.913
E10.4 With neurological complications
0.000 0.102 0.898
E13 Other specified diabetes mellitus
0.000 0.179 0.821
E05.8 Other thyrotoxicosis
0.000 0.188 0.812
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.213 0.787
E16.1 Other hypoglycaemia
0.000 0.224 0.776
E10.7 With multiple complications
0.000 0.251 0.749
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.748 0.252 0.000
E10.0 With coma
0.000 0.279 0.721
E05.5 Thyroid crisis or storm
0.000 0.286 0.714
E05.4 Thyrotoxicosis factitia
0.000 0.286 0.714
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.286 0.714
E12 Malnutrition-related diabetes mellitus
0.000 0.287 0.713
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.712
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.712
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.712
E16.3 Increased secretion of glucagon
0.000 0.288 0.712
E15 Nondiabetic hypoglycaemic coma
0.000 0.288 0.712
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.290 0.710
E00 Congenital iodine-deficiency syndrome
0.000 0.290 0.710
E14 Unspecified diabetes mellitus
0.000 0.295 0.705
E13.9 Without complications
0.000 0.306 0.694
E40-E46 Malnutrition
0.000 0.330 0.670
E10.6 With other specified complications
0.000 0.332 0.668
E10.5 With peripheral circulatory complications
0.000 0.355 0.645
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.364 0.635
E14.3 With ophthalmic complications
0.000 0.390 0.610
E13.3 With ophthalmic complications
0.000 0.407 0.593
E13.8 With unspecified complications
0.000 0.411 0.589
E13.7 With multiple complications
0.000 0.411 0.589
E13.6 With other specified complications
0.000 0.411 0.589
E13.5 With peripheral circulatory complications
0.000 0.411 0.589
E13.4 With neurological complications
0.000 0.411 0.589
E13.2 With renal complications
0.000 0.411 0.589
E13.1 With ketoacidosis
0.000 0.411 0.589
E13.0 With coma
0.000 0.411 0.589
E06 Thyroiditis
0.000 0.413 0.587
E07 Other disorders of thyroid
0.000 0.414 0.586
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.428 0.571
E14.1 With ketoacidosis
0.000 0.431 0.569
E10.8 With unspecified complications
0.000 0.462 0.537
E14.6 With other specified complications
0.000 0.464 0.536
E14.4 With neurological complications
0.000 0.475 0.525
E12.9 Without complications
0.000 0.488 0.511
E12.8 With unspecified complications
0.000 0.488 0.511
E12.7 With multiple complications
0.000 0.488 0.511
E12.6 With other specified complications
0.000 0.488 0.511
E12.5 With peripheral circulatory complications
0.000 0.488 0.511
E12.4 With neurological complications
0.000 0.488 0.511
E12.3 With ophthalmic complications
0.000 0.488 0.511
E12.2 With renal complications
0.000 0.488 0.511
E12.1 With ketoacidosis
0.000 0.488 0.511
E12.0 With coma
0.000 0.488 0.511
E14.8 With unspecified complications
0.000 0.488 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.491 0.509
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.491 0.509
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.491 0.509
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.491 0.509
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.491 0.509
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.491 0.509
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.491 0.509
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.491 0.509
E14.7 With multiple complications
0.000 0.494 0.506
E14.2 Withrenal complications
0.000 0.517 0.483
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.519 0.481
E45 Retarded development following protein-energy malnutrition
0.000 0.519 0.481
E43 Unspecified severe protein-energy malnutrition
0.000 0.519 0.481
E42 Marasmic kwashiorkor
0.000 0.519 0.481
E41 Nutritional marasmus
0.000 0.519 0.481
E40 Kwashiorkor
0.000 0.519 0.481
E14.5 With peripheral circulatory complications
0.000 0.523 0.477
E06.9 Thyroiditis, unspecified
0.000 0.526 0.474
E14.0 With coma
0.000 0.527 0.473
E07.8 Other specified disorders of thyroid
0.000 0.551 0.449
E06.1 Subacute thyroiditis
0.000 0.559 0.441
E46 Unspecified protein-energy malnutrition
0.000 0.561 0.439
E06.4 Drug-induced thyroiditis
0.000 0.579 0.421
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.579 0.421
E06.0 Acute thyroiditis
0.000 0.579 0.421
E07.1 Dyshormogenetic goitre
0.000 0.580 0.420
E07.0 Hypersecretion of calcitonin
0.000 0.580 0.420
K90 Intestinal malabsorption
0.000 0.595 0.405
E06.5 Other chronic thyroiditis
0.000 0.596 0.403
E03 Other hypothyroidism
0.000 0.607 0.393
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.617 0.383
E44.1 Mild protein-energy malnutrition
0.000 0.655 0.345
E44.0 Moderate protein-energy malnutrition
0.000 0.655 0.345
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.656 0.344
E65-E68 Obesity and other hyperalimentation
0.000 0.679 0.321
E50-E64 Other nutritional deficiencies
0.000 0.693 0.307
E11 Non-insulin-dependent diabetes mellitus
0.000 0.699 0.301
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.706 0.294
K90.3 Pancreatic steatorrhoea
0.000 0.710 0.290
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.710 0.290
K90.1 Tropical sprue
0.000 0.710 0.290
E03.5 Myxoedema coma
0.000 0.718 0.282
E03.4 Atrophy of thyroid (acquired)
0.000 0.718 0.282
E03.3 Postinfectious hypothyroidism
0.000 0.718 0.282
E11.6 With other specified complications
0.000 0.722 0.278
K90.8 Other intestinal malabsorption
0.000 0.723 0.277
E03.1 Congenital hypothyroidism without goitre
0.000 0.728 0.271
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.729 0.271
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.729 0.271
E11.1 With ketoacidosis
0.000 0.747 0.253
E11.0 With coma
0.000 0.750 0.250
E07.9 Disorder of thyroid, unspecified
0.000 0.764 0.236
E67 Other hyperalimentation
0.000 0.769 0.230
E68 Sequelae of hyperalimentation
0.000 0.769 0.230
E03.8 Other specified hypothyroidism
0.000 0.772 0.227
E54 Ascorbic acid deficiency
0.000 0.776 0.224
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.779 0.220
E63 Other nutritional deficiencies
0.000 0.779 0.220
E50 Vitamin A deficiency
0.000 0.779 0.220
E60 Dietary zinc deficiency
0.000 0.779 0.220
E59 Dietary selenium deficiency
0.000 0.779 0.220
E52 Niacin deficiency [pellagra]
0.000 0.779 0.220
E51 Thiamine deficiency
0.000 0.781 0.219
E11.2 With renal complications
0.000 0.782 0.218
E11.7 With multiple complications
0.000 0.784 0.216
E56 Other vitamin deficiencies
0.000 0.792 0.208
E83 Disorders of mineral metabolism
0.179 0.796 0.025
M45.X9 Ankylosing spondylitis (Site unspecified)
0.198 0.802 0.000
E55 Vitamin D deficiency
0.000 0.805 0.195
E58 Dietary calcium deficiency
0.000 0.809 0.191
K90.9 Intestinal malabsorption, unspecified
0.000 0.812 0.188
E20-E35 Disorders of other endocrine glands
0.000 0.821 0.179
C15-C26 Malignant neoplasms of digestive organs
0.000 0.821 0.179
E11.8 With unspecified complications
0.000 0.822 0.178
C20 Malignant neoplasm of rectum
0.000 0.823 0.177
C15 Malignant neoplasm of oesophagus
0.000 0.826 0.174
E65 Localised adiposity
0.000 0.828 0.172
E67.8 Other specified hyperalimentation
0.000 0.834 0.165
E67.3 Hypervitaminosis D
0.000 0.834 0.165
E67.2 Megavitamin-B6 syndrome
0.000 0.834 0.165
E67.1 Hypercarotenaemia
0.000 0.834 0.165
E67.0 Hypervitaminosis A
0.000 0.834 0.165
E61 Deficiency of other nutrient elements
0.000 0.835 0.164
E24 Cushing's syndrome
0.000 0.840 0.160
E83.3 Disorders of phosphorus metabolism
0.154 0.840 0.006
E50.9 Vitamin A deficiency, unspecified
0.000 0.842 0.158
E50.8 Other manifestations of vitamin A deficiency
0.000 0.842 0.158
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.842 0.158
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.842 0.158
E50.5 Vitamin A deficiency with night blindness
0.000 0.842 0.158
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.842 0.158
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.842 0.158
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.842 0.158
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.842 0.158
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.842 0.158
E63.9 Nutritional deficiency, unspecified
0.000 0.842 0.158
E63.8 Other specified nutritional deficiencies
0.000 0.842 0.158
E63.1 Imbalance of constituents of food intake
0.000 0.842 0.158
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.842 0.158
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.842 0.158
E64.8 Sequelae of other nutritional deficiencies
0.000 0.842 0.158
E64.3 Sequelae of rickets
0.000 0.842 0.158
E64.2 Sequelae of vitamin C deficiency
0.000 0.842 0.158
E64.1 Sequelae of vitamin A deficiency
0.000 0.842 0.158
E64.0 Sequelae of protein-energy malnutrition
0.000 0.842 0.158
E51.9 Thiamine deficiency, unspecified
0.000 0.843 0.157
E51.8 Other manifestations of thiamine deficiency
0.000 0.843 0.157
E51.1 Beriberi
0.000 0.843 0.157
I83 Varicose veins of lower extremities
0.157 0.843 0.000
E51.2 Wernicke's encephalopathy
0.000 0.844 0.156
C15.4 Middle third of oesophagus
0.000 0.845 0.155
C25 Malignant neoplasm of pancreas
0.000 0.846 0.154
E53 Deficiency of other B group vitamins
0.000 0.847 0.153
C15.5 Lower third of oesophagus
0.000 0.850 0.150
E56.9 Vitamin deficiency, unspecified
0.000 0.851 0.149
E56.8 Deficiency of other vitamins
0.000 0.851 0.149
E56.0 Deficiency of vitamin E
0.000 0.851 0.149
E06.3 Autoimmune thyroiditis
0.001 0.851 0.148
E83.8 Other disorders of mineral metabolism
0.129 0.854 0.018
E83.2 Disorders of zinc metabolism
0.129 0.854 0.018
E83.0 Disorders of copper metabolism
0.129 0.854 0.018
E83.9 Disorder of mineral metabolism, unspecified
0.128 0.854 0.017
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.854 0.146
C15.9 Oesophagus, unspecified
0.000 0.857 0.143
E55.0 Rickets, active
0.000 0.860 0.140
E56.1 Deficiency of vitamin K
0.000 0.863 0.137
E21.3 Hyperparathyroidism, unspecified
0.000 0.863 0.137
E11.5 With peripheral circulatory complications
0.000 0.864 0.136
E28 Ovarian dysfunction
0.000 0.865 0.135
E24.9 Cushing's syndrome, unspecified
0.000 0.866 0.134
E20 Hypoparathyroidism
0.000 0.866 0.134
E24.0 Pituitary-dependent Cushing's disease
0.000 0.867 0.133
C15.3 Upper third of oesophagus
0.000 0.869 0.131
C17 Malignant neoplasm of small intestine
0.000 0.869 0.131
C15.0 Cervical part of oesophagus
0.000 0.870 0.130
C25.2 Tail of pancreas
0.000 0.870 0.130
E14.9 Without complications
0.000 0.871 0.129
E70-E90 Metabolic disorders
0.002 0.871 0.127
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.872 0.128
E32 Diseases of thymus
0.000 0.872 0.128
E30 Disorders of puberty, not elsewhere classified
0.000 0.872 0.128
E25 Adrenogenital disorders
0.000 0.872 0.128
C25.3 Pancreatic duct
0.000 0.872 0.128
C15.1 Thoracic part of oesophagus
0.000 0.874 0.126
E03.9 Hypothyroidism, unspecified
0.000 0.874 0.126
E31 Polyglandular dysfunction
0.000 0.874 0.126
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.875 0.125
C15.8 Overlapping lesion of oesophagus
0.000 0.875 0.125
C15.2 Abdominal part of oesophagus
0.000 0.875 0.125
C25.1 Body of pancreas
0.000 0.875 0.125
C17.0 Duodenum
0.000 0.876 0.124
C25.4 Endocrine pancreas
0.000 0.877 0.123
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.878 0.122
E24.2 Drug-induced Cushing's syndrome
0.000 0.879 0.121
C25.8 Overlapping lesion of pancreas
0.000 0.880 0.120
E78.2 Mixed hyperlipidaemia
0.000 0.881 0.119
E61.9 Deficiency of nutrient element, unspecified
0.000 0.882 0.118
E61.8 Deficiency of other specified nutrient elements
0.000 0.882 0.118
E61.7 Deficiency of multiple nutrient elements
0.000 0.882 0.118
E61.6 Vanadium deficiency
0.000 0.882 0.118
E61.5 Molybdenum deficiency
0.000 0.882 0.118
E61.4 Chromium deficiency
0.000 0.882 0.118
E61.3 Manganese deficiency
0.000 0.882 0.118
E61.0 Copper deficiency
0.000 0.882 0.118
E24.8 Other Cushing's syndrome
0.000 0.884 0.116
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.885 0.115
E24.3 Ectopic ACTH syndrome
0.000 0.885 0.115
E24.1 Nelson's syndrome
0.000 0.885 0.115
E55.9 Vitamin D deficiency, unspecified
0.000 0.886 0.114
C21 Malignant neoplasm of anus and anal canal
0.000 0.886 0.114
E53.9 Vitamin B deficiency, unspecified
0.000 0.888 0.112
I83.0 Varicose veins of lower extremities with ulcer
0.111 0.889 0.000
E29 Testicular dysfunction
0.000 0.889 0.110
C24.0 Extrahepatic bile duct
0.000 0.890 0.110
E53.1 Pyridoxine deficiency
0.000 0.890 0.109
E53.0 Riboflavin deficiency
0.000 0.890 0.109
E28.2 Polycystic ovarian syndrome
0.000 0.892 0.108
C25.9 Pancreas, unspecified
0.000 0.892 0.108
E78.1 Pure hyperglyceridaemia
0.000 0.893 0.107
E21.2 Other hyperparathyroidism
0.000 0.895 0.105
E21.4 Other specified disorders of parathyroid gland
0.000 0.895 0.105
E61.2 Magnesium deficiency
0.000 0.896 0.104
E88 Other metabolic disorders
0.000 0.896 0.104
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.898 0.102
E20.9 Hypoparathyroidism, unspecified
0.000 0.898 0.102
M45 Ankylosing spondylitis
0.101 0.899 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.899 0.100
C25.7 Other parts of pancreas
0.000 0.899 0.100
E34 Other endocrine disorders
0.000 0.900 0.100
E78.5 Hyperlipidaemia, unspecified
0.000 0.901 0.099
E74 Other disorders of carbohydrate metabolism
0.001 0.902 0.097
E78.6 Lipoprotein deficiency
0.000 0.902 0.098
E28.9 Ovarian dysfunction, unspecified
0.000 0.903 0.097
E28.8 Other ovarian dysfunction
0.000 0.903 0.097
E28.1 Androgen excess
0.000 0.903 0.097
E28.0 Oestrogen excess
0.000 0.903 0.097
E20.8 Other hypoparathyroidism
0.000 0.904 0.096
E20.1 Pseudohypoparathyroidism
0.000 0.904 0.096
E20.0 Idiopathic hypoparathyroidism
0.000 0.904 0.096
E11.3 With ophthalmic complications
0.000 0.906 0.094
C17.8 Overlapping lesion of small intestine
0.000 0.906 0.094
C17.3 Meckel's diverticulum
0.000 0.906 0.094
E73 Lactose intolerance
0.001 0.906 0.093
E84 Cystic fibrosis
0.001 0.907 0.092
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.093 0.907 0.000
E77 Disorders of glycoprotein metabolism
0.001 0.907 0.091
E76 Disorders of glycosaminoglycan metabolism
0.001 0.907 0.091
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.907 0.091
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.907 0.091
E30.9 Disorder of puberty, unspecified
0.000 0.908 0.092
E30.8 Other disorders of puberty
0.000 0.908 0.092
E30.1 Precocious puberty
0.000 0.908 0.092
E30.0 Delayed puberty
0.000 0.908 0.092
E32.9 Disease of thymus, unspecified
0.000 0.908 0.092
E32.8 Other diseases of thymus
0.000 0.908 0.092
E32.1 Abscess of thymus
0.000 0.908 0.092
E32.0 Persistent hyperplasia of thymus
0.000 0.908 0.092
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.908 0.092
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.908 0.092
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.908 0.092
E78.3 Hyperchylomicronaemia
0.000 0.908 0.092
E85 Amyloidosis
0.001 0.908 0.091
E25.9 Adrenogenital disorder, unspecified
0.000 0.908 0.092
E25.8 Other adrenogenital disorders
0.000 0.908 0.092
E28.3 Primary ovarian failure
0.000 0.908 0.092
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.909 0.091
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.909 0.091
E31.9 Polyglandular dysfunction, unspecified
0.000 0.909 0.090
E31.8 Other polyglandular dysfunction
0.000 0.909 0.090
E31.1 Polyglandular hyperfunction
0.000 0.909 0.090
C24.8 Overlapping lesion of biliary tract
0.000 0.910 0.090
E88.9 Metabolic disorder, unspecified
0.000 0.910 0.090
E31.0 Autoimmune polyglandular failure
0.000 0.912 0.088
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.912 0.088
E70 Disorders of aromatic amino-acid metabolism
0.001 0.912 0.087
E79 Disorders of purine and pyrimidine metabolism
0.001 0.913 0.085
E61.1 Iron deficiency
0.000 0.914 0.086
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.915 0.085
C24.9 Biliary tract, unspecified
0.000 0.915 0.085
E72 Other disorders of amino-acid metabolism
0.001 0.916 0.083
E26 Hyperaldosteronism
0.000 0.916 0.084
C17.1 Jejunum
0.000 0.916 0.083
C23 Malignant neoplasm of gallbladder
0.000 0.917 0.083
C21.2 Cloacogenic zone
0.000 0.918 0.082
E88.2 Lipomatosis, not elsewhere classified
0.000 0.918 0.081
E29.9 Testicular dysfunction, unspecified
0.000 0.919 0.081
M45.X2 Ankylosing spondylitis (Cervical region)
0.080 0.920 0.000
E75.5 Other lipid storage disorders
0.001 0.920 0.079
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.920 0.079
E29.8 Other testicular dysfunction
0.000 0.920 0.079
E29.0 Testicular hyperfunction
0.000 0.920 0.079
M45.X6 Ankylosing spondylitis (Lumbar region)
0.078 0.922 0.000
E21.0 Primary hyperparathyroidism
0.000 0.922 0.078
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.922 0.078
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.922 0.078
E78.4 Other hyperlipidaemia
0.000 0.922 0.078
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.922 0.077
E85.4 Organ-limited amyloidosis
0.000 0.924 0.075
E83.4 Disorders of magnesium metabolism
0.065 0.925 0.010
E75.2 Other sphingolipidosis
0.001 0.927 0.073
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.073 0.927 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.073 0.927 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.073 0.927 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.073 0.927 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.073 0.927 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.073 0.927 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.927 0.073
E75.6 Lipid storage disorder, unspecified
0.001 0.928 0.072
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.928 0.072
E75.3 Sphingolipidosis, unspecified
0.001 0.928 0.072
E75.1 Other gangliosidosis
0.001 0.928 0.072
E75.0 GM2 gangliosidosis
0.001 0.928 0.072
E34.5 Androgen resistance syndrome
0.000 0.928 0.072
E34.4 Constitutional tall stature
0.000 0.928 0.072
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.928 0.072
E34.1 Other hypersecretion of intestinal hormones
0.000 0.928 0.072
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.929 0.071
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.929 0.070
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.929 0.070
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.929 0.070
E74.2 Disorders of galactose metabolism
0.001 0.929 0.070
E74.1 Disorders of fructose metabolism
0.001 0.929 0.070
E88.8 Other specified metabolic disorders
0.000 0.930 0.070
C21.0 Anus, unspecified
0.000 0.930 0.070
E23 Hypofunction and other disorders of pituitary gland
0.000 0.930 0.070
E22 Hyperfunction of pituitary gland
0.000 0.931 0.069
E85.3 Secondary systemic amyloidosis
0.001 0.931 0.068
E73.9 Lactose intolerance, unspecified
0.001 0.931 0.068
E74.0 Glycogen storage disease
0.001 0.931 0.068
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.931 0.068
E73.8 Other lactose intolerance
0.001 0.932 0.067
E73.1 Secondary lactase deficiency
0.001 0.932 0.067
E73.0 Congenital lactase deficiency
0.001 0.932 0.067
E84.8 Cystic fibrosis with other manifestations
0.001 0.933 0.066
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.933 0.066
E34.8 Other specified endocrine disorders
0.000 0.933 0.067
E85.8 Other amyloidosis
0.001 0.933 0.066
E71.3 Disorders of fatty-acid metabolism
0.001 0.933 0.066
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.933 0.066
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.933 0.066
E71.0 Maple-syrup-urine disease
0.001 0.933 0.066
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.933 0.066
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.933 0.066
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.933 0.066
E76.2 Other mucopolysaccharidoses
0.001 0.933 0.066
E76.1 Mucopolysaccharidosis, type II
0.001 0.933 0.066
E76.0 Mucopolysaccharidosis, type I
0.001 0.933 0.066
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.933 0.066
E77.8 Other disorders of glycoprotein metabolism
0.001 0.933 0.066
E77.1 Defects in glycoprotein degradation
0.001 0.933 0.066
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.933 0.066
E84.9 Cystic fibrosis, unspecified
0.001 0.934 0.066
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.934 0.065
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.934 0.065
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.934 0.065
C21.1 Anal canal
0.000 0.934 0.066
E34.9 Endocrine disorder, unspecified
0.000 0.935 0.065
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.937 0.062
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.937 0.062
E70.2 Disorders of tyrosine metabolism
0.001 0.937 0.062
E70.1 Other hyperphenylalaninaemias
0.001 0.937 0.062
E70.0 Classical phenylketonuria
0.001 0.937 0.062
C17.9 Small intestine, unspecified
0.000 0.938 0.062
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.938 0.061
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.938 0.061
E79.1 Lesch-Nyhan syndrome
0.001 0.938 0.061
E11.4 With neurological complications
0.000 0.938 0.062
E88.3 Tumour lysis syndrome
0.001 0.938 0.061
C17.2 Ileum
0.000 0.939 0.061
I83.1 Varicose veins of lower extremities with inflammation
0.061 0.939 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.939 0.060
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.939 0.060
E72.5 Disorders of glycine metabolism
0.001 0.939 0.060
E72.4 Disorders of ornithine metabolism
0.001 0.939 0.060
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.939 0.060
E72.2 Disorders of urea cycle metabolism
0.001 0.939 0.060
E26.8 Other hyperaldosteronism
0.000 0.939 0.060
E26.1 Secondary hyperaldosteronism
0.000 0.939 0.060
E23.7 Disorder of pituitary gland, unspecified
0.000 0.940 0.060
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.060 0.940 0.000
E29.1 Testicular hypofunction
0.000 0.940 0.059
E34.0 Carcinoid syndrome
0.000 0.941 0.059
E72.0 Disorders of amino-acid transport
0.001 0.941 0.058
E70.3 Albinism
0.001 0.941 0.057
C22.9 Liver, unspecified
0.000 0.943 0.056
C22.7 Other specified carcinomas of liver
0.000 0.944 0.056
C22.4 Other sarcomas of liver
0.000 0.944 0.056
C22.3 Angiosarcoma of liver
0.000 0.944 0.056
C22.2 Hepatoblastoma
0.000 0.944 0.056
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.944 0.055
C26.8 Overlapping lesion of digestive system
0.000 0.944 0.056
C26.1 Spleen
0.000 0.944 0.056
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.945 0.053
E26.9 Hyperaldosteronism, unspecified
0.001 0.947 0.053
E78.8 Other disorders of lipoprotein metabolism
0.000 0.948 0.052
C22.1 Intrahepatic bile duct carcinoma
0.000 0.948 0.052
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.950 0.050
E23.1 Drug-induced hypopituitarism
0.000 0.950 0.050
E22.8 Other hyperfunction of pituitary gland
0.000 0.950 0.050
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.950 0.048
C24.1 Ampulla of Vater
0.001 0.951 0.048
E04 Other non-toxic goitre
0.002 0.952 0.045
E22.1 Hyperprolactinaemia
0.000 0.953 0.047
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.953 0.046
R31 Unspecified haematuria
0.046 0.954 0.000
C25.0 Head of pancreas
0.000 0.954 0.046
E85.9 Amyloidosis, unspecified
0.001 0.956 0.043
E78.0 Pure hypercholesterolaemia
0.000 0.956 0.044
C26.9 Ill-defined sites within the digestive system
0.001 0.960 0.039
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.962 0.038
E80.2 Other porphyria
0.001 0.962 0.037
C16 Malignant neoplasm of stomach
0.000 0.964 0.036
C26.0 Intestinal tract, part unspecified
0.000 0.964 0.036
E23.6 Other disorders of pituitary gland
0.000 0.964 0.035
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.964 0.035
E80.5 Crigler-Najjar syndrome
0.001 0.964 0.035
E80.3 Defects of catalase and peroxydase
0.001 0.964 0.035
E80.0 Hereditary erythropoietic porphyria
0.001 0.964 0.035
C18 Malignant neoplasm of colon
0.000 0.964 0.036
C18.1 Appendix
0.000 0.965 0.035
E23.2 Diabetes insipidus
0.000 0.965 0.034
E53.8 Deficiency of other specified B group vitamins
0.000 0.966 0.034
E04.8 Other specified non-toxic goitre
0.002 0.966 0.033
I73.9 Peripheral vascular disease, unspecified
0.000 0.966 0.034
I73 Other peripheral vascular diseases
0.000 0.967 0.033
C18.9 Colon, unspecified
0.000 0.967 0.033
I77 Other disorders of arteries and arterioles
0.000 0.967 0.033
E26.0 Primary hyperaldosteronism
0.001 0.968 0.031
E22.0 Acromegaly and pituitary gigantism
0.000 0.968 0.031
I77.6 Arteritis, unspecified
0.000 0.969 0.031
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.969 0.031
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.969 0.031
E80.6 Other disorders of bilirubin metabolism
0.001 0.970 0.029
E80.1 Porphyria cutanea tarda
0.001 0.970 0.029
I73.0 Raynaud's syndrome
0.000 0.970 0.030
I77.8 Other specified disorders of arteries and arterioles
0.000 0.972 0.028
E66 Obesity
0.000 0.972 0.028
I74 Arterial embolism and thrombosis
0.000 0.973 0.027
I72 Other aneurysm
0.000 0.973 0.027
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.026 0.974 0.000
C16.2 Body of stomach
0.000 0.974 0.026
E04.0 Non-toxic diffuse goitre
0.002 0.974 0.024
I74.5 Embolism and thrombosis of iliac artery
0.000 0.974 0.026
I73.8 Other specified peripheral vascular diseases
0.000 0.974 0.025
C18.8 Overlapping lesion of colon
0.000 0.974 0.025
E27 Other disorders of adrenal gland
0.000 0.975 0.025
I77.3 Arterial fibromuscular dysplasia
0.000 0.975 0.025
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.975 0.025
K90-K93 Other diseases of the digestive system
0.000 0.975 0.025
C16.6 Greater curvature of stomach, unspecified
0.000 0.976 0.024
E83.5 Disorders of calcium metabolism
0.007 0.976 0.018
C16.5 Lesser curvature of stomach, unspecified
0.000 0.976 0.024
I70 Atherosclerosis
0.000 0.976 0.024
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.024 0.976 0.000
C16.0 Cardia
0.000 0.976 0.024
I77.2 Rupture of artery
0.000 0.976 0.024
I77.5 Necrosis of artery
0.000 0.976 0.024
I77.4 Coeliac artery compression syndrome
0.000 0.976 0.024
I72.4 Aneurysm of artery of lower extremity
0.000 0.976 0.024
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.976 0.023
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.977 0.023
C16.8 Overlapping lesion of stomach
0.000 0.977 0.023
I86 Varicose veins of other sites
0.023 0.977 0.000
C16.4 Pylorus
0.000 0.977 0.023
C18.6 Descending colon
0.000 0.977 0.023
I77.1 Stricture of artery
0.000 0.978 0.022
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.978 0.022
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.022 0.978 0.000
M45-M49 Spondylopathies
0.022 0.978 0.000
I86.8 Varicose veins of other specified sites
0.022 0.978 0.000
I89.0 Lymphoedema, not elsewhere classified
0.022 0.978 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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