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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1002985
log Bayes Factor = 12.1832
Chromosome 6   position 32,852,448  (GRCh37) Explore rs1002985 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.000 0.003 0.997
E10-E14 Diabetes mellitus
0.000 0.020 0.980
E11 Non-insulin-dependent diabetes mellitus
0.000 0.036 0.964
E11.9 Without complications
0.000 0.057 0.943
E10.1 With ketoacidosis
0.000 0.066 0.934
E10.4 With neurological complications
0.000 0.081 0.919
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.184 0.816
E11.2 With renal complications
0.000 0.189 0.811
E00-E07 Disorders of thyroid gland
0.000 0.201 0.799
E03 Other hypothyroidism
0.000 0.209 0.791
E03.9 Hypothyroidism, unspecified
0.000 0.214 0.786
K90.0 Coeliac disease
0.000 0.225 0.775
G35-G37 Demyelinating diseases of the central nervous system
0.766 0.234 0.000
E11.3 With ophthalmic complications
0.000 0.258 0.742
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.262 0.738
E11.4 With neurological complications
0.000 0.277 0.723
E11.1 With ketoacidosis
0.000 0.280 0.720
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.5 With peripheral circulatory complications
0.000 0.283 0.717
E10.2 With renal complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E13 Other specified diabetes mellitus
0.000 0.292 0.708
E12 Malnutrition-related diabetes mellitus
0.000 0.297 0.703
E11.7 With multiple complications
0.000 0.309 0.691
E11.6 With other specified complications
0.000 0.309 0.691
E11.0 With coma
0.000 0.316 0.684
E16 Other disorders of pancreatic internal secretion
0.000 0.317 0.683
E11.5 With peripheral circulatory complications
0.000 0.339 0.661
E70-E90 Metabolic disorders
0.000 0.354 0.646
E07 Other disorders of thyroid
0.000 0.357 0.643
E16.2 Hypoglycaemia, unspecified
0.000 0.357 0.643
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.382 0.618
E40-E46 Malnutrition
0.000 0.388 0.612
G37 Other demyelinating diseases of central nervous system
0.606 0.394 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.395 0.605
E06 Thyroiditis
0.000 0.398 0.602
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.403 0.597
E03.8 Other specified hypothyroidism
0.000 0.410 0.590
E11.8 With unspecified complications
0.000 0.414 0.585
E14 Unspecified diabetes mellitus
0.000 0.425 0.575
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.427 0.573
E00 Congenital iodine-deficiency syndrome
0.000 0.427 0.573
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.427 0.573
E03.5 Myxoedema coma
0.000 0.432 0.567
E03.4 Atrophy of thyroid (acquired)
0.000 0.432 0.567
E03.3 Postinfectious hypothyroidism
0.000 0.432 0.567
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.432 0.567
E03.1 Congenital hypothyroidism without goitre
0.000 0.432 0.567
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.432 0.567
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.439 0.561
G36 Other acute disseminated demyelination
0.549 0.451 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.458 0.542
Chapter VI Diseases of the nervous system
0.539 0.461 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.471 0.529
E88 Other metabolic disorders
0.000 0.478 0.522
G80-G83 Cerebral palsy and other paralytic syndromes
0.521 0.479 0.000
E13.9 Without complications
0.000 0.487 0.513
E13.8 With unspecified complications
0.000 0.492 0.508
E13.7 With multiple complications
0.000 0.492 0.508
E13.6 With other specified complications
0.000 0.492 0.508
E13.5 With peripheral circulatory complications
0.000 0.492 0.508
E13.4 With neurological complications
0.000 0.492 0.508
E13.3 With ophthalmic complications
0.000 0.492 0.508
E13.2 With renal complications
0.000 0.492 0.508
E13.1 With ketoacidosis
0.000 0.492 0.508
E13.0 With coma
0.000 0.492 0.508
E12.9 Without complications
0.000 0.496 0.504
E12.8 With unspecified complications
0.000 0.496 0.504
E12.7 With multiple complications
0.000 0.496 0.504
E12.6 With other specified complications
0.000 0.496 0.504
E12.5 With peripheral circulatory complications
0.000 0.496 0.504
E12.4 With neurological complications
0.000 0.496 0.504
E12.3 With ophthalmic complications
0.000 0.496 0.504
E12.2 With renal complications
0.000 0.496 0.504
E12.1 With ketoacidosis
0.000 0.496 0.504
E12.0 With coma
0.000 0.496 0.504
G37.9 Demyelinating disease of central nervous system, unspecified
0.504 0.496 0.000
G82 Paraplegia and tetraplegia
0.498 0.502 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.503 0.497
G70-G73 Diseases of myoneural junction and muscle
0.496 0.504 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.510 0.489
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.510 0.489
E16.4 Abnormal secretion of gastrin
0.000 0.510 0.489
E16.3 Increased secretion of glucagon
0.000 0.510 0.489
E16.1 Other hypoglycaemia
0.000 0.510 0.489
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.510 0.489
G83 Other paralytic syndromes
0.477 0.523 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.527 0.473
E89.0 Postprocedural hypothyroidism
0.000 0.530 0.470
E78.8 Other disorders of lipoprotein metabolism
0.000 0.533 0.467
E46 Unspecified protein-energy malnutrition
0.000 0.534 0.466
E84 Cystic fibrosis
0.000 0.537 0.463
E79 Disorders of purine and pyrimidine metabolism
0.000 0.537 0.463
E77 Disorders of glycoprotein metabolism
0.000 0.537 0.463
E76 Disorders of glycosaminoglycan metabolism
0.000 0.537 0.463
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.537 0.463
E72 Other disorders of amino-acid metabolism
0.000 0.537 0.463
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.537 0.463
E70 Disorders of aromatic amino-acid metabolism
0.000 0.537 0.463
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.537 0.463
E07.1 Dyshormogenetic goitre
0.000 0.538 0.461
E07.0 Hypersecretion of calcitonin
0.000 0.538 0.461
E06.3 Autoimmune thyroiditis
0.000 0.539 0.461
E85 Amyloidosis
0.000 0.539 0.460
E78.2 Mixed hyperlipidaemia
0.000 0.544 0.456
G82.2 Paraplegia, unspecified
0.450 0.550 0.000
G71 Primary disorders of muscles
0.449 0.551 0.000
E73 Lactose intolerance
0.000 0.552 0.448
E07.8 Other specified disorders of thyroid
0.000 0.556 0.444
E78.6 Lipoprotein deficiency
0.000 0.557 0.443
E78.4 Other hyperlipidaemia
0.000 0.557 0.443
E78.3 Hyperchylomicronaemia
0.000 0.557 0.443
E89.2 Postprocedural hypoparathyroidism
0.000 0.558 0.442
E65-E68 Obesity and other hyperalimentation
0.000 0.561 0.439
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.561 0.439
E45 Retarded development following protein-energy malnutrition
0.000 0.561 0.439
E43 Unspecified severe protein-energy malnutrition
0.000 0.561 0.439
E42 Marasmic kwashiorkor
0.000 0.561 0.439
E41 Nutritional marasmus
0.000 0.561 0.439
E40 Kwashiorkor
0.000 0.561 0.439
E74 Other disorders of carbohydrate metabolism
0.000 0.564 0.436
G37.8 Other specified demyelinating diseases of central nervous system
0.435 0.565 0.000
G37.5 Concentric sclerosis [Balo]
0.435 0.565 0.000
G37.4 Subacute necrotising myelitis
0.435 0.565 0.000
G37.2 Central pontine myelinolysis
0.435 0.565 0.000
G37.1 Central demyelination of corpus callosum
0.435 0.565 0.000
G37.0 Diffuse sclerosis
0.435 0.565 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.565 0.435
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.566 0.434
E06.9 Thyroiditis, unspecified
0.000 0.568 0.432
E06.5 Other chronic thyroiditis
0.000 0.568 0.432
E06.4 Drug-induced thyroiditis
0.000 0.568 0.432
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.568 0.432
E06.1 Subacute thyroiditis
0.000 0.568 0.432
E06.0 Acute thyroiditis
0.000 0.568 0.432
E05.8 Other thyrotoxicosis
0.000 0.572 0.428
E05.5 Thyroid crisis or storm
0.000 0.572 0.428
E05.4 Thyrotoxicosis factitia
0.000 0.572 0.428
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.572 0.428
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.572 0.428
G82.1 Spastic paraplegia
0.424 0.575 0.000
E14.3 With ophthalmic complications
0.000 0.580 0.420
G90-G99 Other disorders of the nervous system
0.418 0.582 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.418 0.582 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.582 0.417
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.414 0.586 0.000
E14.8 With unspecified complications
0.000 0.588 0.412
E14.7 With multiple complications
0.000 0.588 0.412
E14.6 With other specified complications
0.000 0.588 0.412
E14.5 With peripheral circulatory complications
0.000 0.588 0.412
E14.4 With neurological complications
0.000 0.588 0.412
E14.2 Withrenal complications
0.000 0.588 0.412
E14.1 With ketoacidosis
0.000 0.588 0.412
E14.0 With coma
0.000 0.588 0.412
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.589 0.411
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.589 0.411
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.589 0.411
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.589 0.411
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.589 0.411
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.589 0.411
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.589 0.411
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.589 0.411
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.598 0.402
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.598 0.402
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.598 0.402
E89.5 Postprocedural testicular hypofunction
0.000 0.598 0.402
E89.4 Postprocedural ovarian failure
0.000 0.598 0.402
E89.1 Postprocedural hypoinsulinaemia
0.000 0.598 0.402
G83.4 Cauda equina syndrome
0.400 0.600 0.000
G82.5 Tetraplegia, unspecified
0.399 0.601 0.000
G83.9 Paralytic syndrome, unspecified
0.396 0.604 0.000
G36.9 Acute disseminated demyelination, unspecified
0.394 0.606 0.000
G36.8 Other specified acute disseminated demyelination
0.394 0.606 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.394 0.606 0.000
G36.0 Neuromyelitis optica [Devic]
0.394 0.606 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.607 0.393
E86 Volume depletion
0.000 0.609 0.391
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.386 0.614 0.000
G70 Myasthenia gravis and other myoneural disorders
0.383 0.617 0.000
G83.1 Monoplegia of lower limb
0.383 0.617 0.000
G72 Other myopathies
0.383 0.617 0.000
E83 Disorders of mineral metabolism
0.000 0.623 0.377
E78.5 Hyperlipidaemia, unspecified
0.000 0.624 0.376
E88.9 Metabolic disorder, unspecified
0.000 0.625 0.375
E88.8 Other specified metabolic disorders
0.000 0.625 0.375
E88.3 Tumour lysis syndrome
0.000 0.625 0.375
E88.2 Lipomatosis, not elsewhere classified
0.000 0.625 0.375
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.625 0.375
G95 Other diseases of spinal cord
0.374 0.626 0.000
G71.0 Muscular dystrophy
0.373 0.627 0.000
G30-G32 Other degenerative diseases of the nervous system
0.368 0.632 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.634 0.365
G71.3 Mitochondrial myopathy, not elsewhere classified
0.366 0.634 0.000
G71.1 Myotonic disorders
0.361 0.639 0.000
G82.4 Spastic tetraplegia
0.357 0.643 0.000
G82.3 Flaccid tetraplegia
0.357 0.643 0.000
G82.0 Flaccid paraplegia
0.357 0.643 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.356 0.644 0.000
G80 Infantile cerebral palsy
0.346 0.653 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.343 0.657 0.000
G83.8 Other specified paralytic syndromes
0.342 0.658 0.000
G83.5 Locked-in syndrome
0.342 0.658 0.000
G83.3 Monoplegia, unspecified
0.342 0.658 0.000
G83.2 Monoplegia of upper limb
0.342 0.658 0.000
G83.0 Diplegia of upper limbs
0.342 0.658 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.668 0.332
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.668 0.332
E70.3 Albinism
0.000 0.668 0.332
E70.2 Disorders of tyrosine metabolism
0.000 0.668 0.332
E70.1 Other hyperphenylalaninaemias
0.000 0.668 0.332
E70.0 Classical phenylketonuria
0.000 0.668 0.332
E71.3 Disorders of fatty-acid metabolism
0.000 0.668 0.332
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.668 0.332
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.668 0.332
E71.0 Maple-syrup-urine disease
0.000 0.668 0.332
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.668 0.332
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.668 0.332
E72.5 Disorders of glycine metabolism
0.000 0.668 0.332
E72.4 Disorders of ornithine metabolism
0.000 0.668 0.332
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.668 0.332
E72.2 Disorders of urea cycle metabolism
0.000 0.668 0.332
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.668 0.332
E72.0 Disorders of amino-acid transport
0.000 0.668 0.332
E75.6 Lipid storage disorder, unspecified
0.000 0.668 0.332
E75.5 Other lipid storage disorders
0.000 0.668 0.332
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.668 0.332
E75.3 Sphingolipidosis, unspecified
0.000 0.668 0.332
E75.2 Other sphingolipidosis
0.000 0.668 0.332
E75.1 Other gangliosidosis
0.000 0.668 0.332
E75.0 GM2 gangliosidosis
0.000 0.668 0.332
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.668 0.332
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.668 0.332
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.668 0.332
E76.2 Other mucopolysaccharidoses
0.000 0.668 0.332
E76.1 Mucopolysaccharidosis, type II
0.000 0.668 0.332
E76.0 Mucopolysaccharidosis, type I
0.000 0.668 0.332
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.668 0.332
E77.8 Other disorders of glycoprotein metabolism
0.000 0.668 0.332
E77.1 Defects in glycoprotein degradation
0.000 0.668 0.332
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.668 0.332
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.668 0.332
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.668 0.332
E79.1 Lesch-Nyhan syndrome
0.000 0.668 0.332
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.668 0.332
E84.9 Cystic fibrosis, unspecified
0.000 0.668 0.332
E84.8 Cystic fibrosis with other manifestations
0.000 0.668 0.332
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.668 0.332
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.668 0.332
E85.9 Amyloidosis, unspecified
0.000 0.670 0.330
E85.8 Other amyloidosis
0.000 0.670 0.330
E85.3 Secondary systemic amyloidosis
0.000 0.670 0.330
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.670 0.330
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.670 0.330
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.670 0.330
G98 Other disorders of nervous system, not elsewhere classified
0.330 0.670 0.000
G95.9 Disease of spinal cord, unspecified
0.328 0.672 0.000
E85.4 Organ-limited amyloidosis
0.000 0.672 0.328
E50-E64 Other nutritional deficiencies
0.001 0.674 0.325
E65 Localised adiposity
0.000 0.674 0.326
G71.9 Primary disorder of muscle, unspecified
0.322 0.678 0.000
G71.8 Other primary disorders of muscles
0.322 0.678 0.000
G71.2 Congenital myopathies
0.322 0.678 0.000
E73.8 Other lactose intolerance
0.000 0.679 0.321
E73.1 Secondary lactase deficiency
0.000 0.679 0.321
E73.0 Congenital lactase deficiency
0.000 0.679 0.321
E67 Other hyperalimentation
0.000 0.685 0.315
E68 Sequelae of hyperalimentation
0.000 0.685 0.315
E44.1 Mild protein-energy malnutrition
0.000 0.685 0.315
E44.0 Moderate protein-energy malnutrition
0.000 0.685 0.315
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.687 0.312
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.687 0.312
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.687 0.312
E74.2 Disorders of galactose metabolism
0.000 0.687 0.312
E74.1 Disorders of fructose metabolism
0.000 0.687 0.312
E74.0 Glycogen storage disease
0.000 0.687 0.312
G40-G47 Episodic and paroxysmal disorders
0.312 0.688 0.000
J18.1 Lobar pneumonia, unspecified
0.310 0.690 0.000
K90 Intestinal malabsorption
0.000 0.693 0.307
E73.9 Lactose intolerance, unspecified
0.000 0.694 0.306
G95.1 Vascular myelopathies
0.304 0.696 0.000
G70.0 Myasthenia gravis
0.303 0.697 0.000
G72.9 Myopathy, unspecified
0.301 0.698 0.000
G81 Hemiplegia
0.301 0.699 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.300 0.700 0.000
G95.8 Other specified diseases of spinal cord
0.300 0.700 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.300 0.700 0.000
G92 Toxic encephalopathy
0.300 0.700 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.300 0.700 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.300 0.700 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.300 0.700 0.000
G00 Bacterial meningitis, not elsewhere classified
0.300 0.700 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.300 0.700 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.300 0.700 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.300 0.700 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.300 0.700 0.000
E83.5 Disorders of calcium metabolism
0.000 0.701 0.299
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.299 0.701 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.296 0.704 0.000
G96 Other disorders of central nervous system
0.291 0.709 0.000
G90 Disorders of autonomic nervous system
0.288 0.712 0.000
G20-G26 Extrapyramidal and movement disorders
0.286 0.714 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.715 0.285
G30 Alzheimer's disease
0.283 0.716 0.000
G91 Hydrocephalus
0.280 0.720 0.000
G03 Meningitis due to other and unspecified causes
0.280 0.720 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.277 0.723 0.000
G11 Hereditary ataxia
0.277 0.723 0.000
G14 Postpolio syndrome
0.277 0.723 0.000
G10 Huntington's disease
0.277 0.723 0.000
G12 Spinal muscular atrophy and related syndromes
0.276 0.724 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.724 0.276
G70.9 Myoneural disorder, unspecified
0.275 0.725 0.000
G70.8 Other specified myoneural disorders
0.275 0.725 0.000
G70.2 Congenital and developmental myasthenia
0.275 0.725 0.000
G70.1 Toxic myoneural disorders
0.275 0.725 0.000
G72.8 Other specified myopathies
0.274 0.725 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.274 0.725 0.000
G72.3 Periodic paralysis
0.274 0.725 0.000
G72.2 Myopathy due to other toxic agents
0.274 0.725 0.000
G72.1 Alcoholic myopathy
0.274 0.725 0.000
G72.0 Drug-induced myopathy
0.274 0.725 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.273 0.726 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.730 0.270
E83.8 Other disorders of mineral metabolism
0.000 0.730 0.270
E83.2 Disorders of zinc metabolism
0.000 0.730 0.270
E83.0 Disorders of copper metabolism
0.000 0.730 0.270
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.269 0.731 0.000
G95.0 Syringomyelia and syringobulbia
0.268 0.731 0.000
E14.9 Without complications
0.000 0.732 0.268
E05.9 Thyrotoxicosis, unspecified
0.000 0.732 0.268
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.264 0.736 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.738 0.262
E80.6 Other disorders of bilirubin metabolism
0.000 0.738 0.262
E80.5 Crigler-Najjar syndrome
0.000 0.738 0.262
E80.3 Defects of catalase and peroxydase
0.000 0.738 0.262
E80.2 Other porphyria
0.000 0.738 0.262
E80.1 Porphyria cutanea tarda
0.000 0.738 0.262
E80.0 Hereditary erythropoietic porphyria
0.000 0.738 0.262
G73.7 Myopathy other diseases classified elsewhere
0.255 0.745 0.000
G73.6 Myopathy in metabolic diseases
0.255 0.745 0.000
G73.5 Myopathy in endocrine diseases
0.255 0.745 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.255 0.745 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.255 0.745 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.255 0.745 0.000
G73.1 Eaton-Lambert syndrome
0.255 0.745 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.255 0.745 0.000
G80.8 Other infantile cerebral palsy
0.248 0.751 0.000
G80.4 Ataxic cerebral palsy
0.248 0.751 0.000
G80.3 Dyskinetic cerebral palsy
0.248 0.751 0.000
G80.2 Infantile hemiplegia
0.248 0.751 0.000
G80.1 Spastic diplegia
0.248 0.751 0.000
G80.0 Spastic cerebral palsy
0.248 0.751 0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.246 0.754 0.000
G04.1 Tropical spastic paraplegia
0.246 0.754 0.000
G04.0 Acute disseminated encephalitis
0.246 0.754 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.756 0.244
G41 Status epilepticus
0.243 0.757 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.236 0.764 0.000
G61 Inflammatory polyneuropathy
0.234 0.766 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.766 0.233
E63 Other nutritional deficiencies
0.001 0.766 0.233
E56 Other vitamin deficiencies
0.001 0.766 0.233
E51 Thiamine deficiency
0.001 0.766 0.233
E50 Vitamin A deficiency
0.001 0.766 0.233
E60 Dietary zinc deficiency
0.001 0.766 0.233
E59 Dietary selenium deficiency
0.001 0.766 0.233
E58 Dietary calcium deficiency
0.001 0.766 0.233
E54 Ascorbic acid deficiency
0.001 0.766 0.233
E52 Niacin deficiency [pellagra]
0.001 0.766 0.233
G44 Other headache syndromes
0.233 0.767 0.000
E67.8 Other specified hyperalimentation
0.000 0.774 0.226
E67.3 Hypervitaminosis D
0.000 0.774 0.226
E67.2 Megavitamin-B6 syndrome
0.000 0.774 0.226
E67.1 Hypercarotenaemia
0.000 0.774 0.226
E67.0 Hypervitaminosis A
0.000 0.774 0.226
E20-E35 Disorders of other endocrine glands
0.001 0.774 0.225
G46 Vascular syndromes of brain in cerebrovascular diseases
0.224 0.776 0.000
G30.9 Alzheimer's disease, unspecified
0.223 0.777 0.000
G80.9 Infantile cerebral palsy, unspecified
0.221 0.779 0.000
K90.8 Other intestinal malabsorption
0.000 0.779 0.220
K90.3 Pancreatic steatorrhoea
0.000 0.779 0.220
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.779 0.220
K90.1 Tropical sprue
0.000 0.779 0.220
G95.2 Cord compression, unspecified
0.220 0.779 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.218 0.782 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.217 0.783 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.216 0.784 0.000
G81.1 Spastic hemiplegia
0.216 0.784 0.000
G81.0 Flaccid hemiplegia
0.216 0.784 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.215 0.784 0.000
G97.8 Other postprocedural disorders of nervous system
0.215 0.784 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.215 0.784 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.215 0.784 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.215 0.785 0.000
G94.2 Hydrocephalus in other diseases classified elsewhere
0.215 0.785 0.000
G94.1 Hydrocephalus in neoplastic disease
0.215 0.785 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.215 0.785 0.000
G00.9 Bacterial meningitis, unspecified
0.215 0.785 0.000
G00.8 Other bacterial meningitis
0.215 0.785 0.000
G00.3 Staphylococcal meningitis
0.215 0.785 0.000
G00.2 Streptococcal meningitis
0.215 0.785 0.000
G00.1 Pneumococcal meningitis
0.215 0.785 0.000
G00.0 Haemophilus meningitis
0.215 0.785 0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.215 0.785 0.000
G02.1 Meningitis in mycoses
0.215 0.785 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.215 0.785 0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.215 0.785 0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.215 0.785 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.215 0.785 0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.215 0.785 0.000
G06.2 Extradural and subdural abscess, unspecified
0.215 0.785 0.000
G06.1 Intraspinal abscess and granuloma
0.215 0.785 0.000
G06.0 Intracranial abscess and granuloma
0.215 0.785 0.000
G64 Other disorders of peripheral nervous system
0.214 0.785 0.000
G60 Hereditary and idiopathic neuropathy
0.214 0.786 0.000
G40 Epilepsy
0.213 0.787 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.213 0.787 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.213 0.787 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.210 0.790 0.000
G96.9 Disorder of central nervous system, unspecified
0.208 0.791 0.000
G96.8 Other specified disorders of central nervous system
0.208 0.791 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.208 0.791 0.000
E61 Deficiency of other nutrient elements
0.001 0.793 0.206
G90.8 Other disorders of autonomic nervous system
0.207 0.793 0.000
G90.4 Autonomic dysreflexia
0.207 0.793 0.000
G90.3 Multisystem degeneration
0.207 0.793 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.207 0.793 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.206 0.793 0.000
J18 Pneumonia, organism unspecified
0.206 0.794 0.000
E04 Other non-toxic goitre
0.000 0.794 0.205
G23 Other degenerative diseases of basal ganglia
0.205 0.795 0.000
G21 Secondary Parkinsonism
0.205 0.795 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.205 0.795 0.000
G22 Parkinsonism in diseases classified elsewhere
0.205 0.795 0.000
G30.8 Other Alzheimer's disease
0.203 0.796 0.000
G30.1 Alzheimer's disease with late onset
0.203 0.796 0.000
G30.0 Alzheimer's disease with early onset
0.203 0.796 0.000
G91.8 Other hydrocephalus
0.201 0.799 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.201 0.799 0.000
G91.2 Normal-pressure hydrocephalus
0.201 0.799 0.000
G91.1 Obstructive hydrocephalus
0.201 0.799 0.000
G91.0 Communicating hydrocephalus
0.201 0.799 0.000
G03.8 Meningitis due to other specified causes
0.201 0.799 0.000
G03.2 Benign recurrent meningitis [Mollaret]
0.201 0.799 0.000
G03.1 Chronic meningitis
0.201 0.799 0.000
G03.0 Nonpyogenic meningitis
0.201 0.799 0.000
G24 Dystonia
0.201 0.799 0.000
G96.0 Cerebrospinal fluid leak
0.199 0.800 0.000
G11.9 Hereditary ataxia, unspecified
0.198 0.801 0.000
G11.8 Other hereditary ataxias
0.198 0.801 0.000
G11.4 Hereditary spastic paraplegia
0.198 0.801 0.000
G11.3 Cerebellar ataxia with defective DNA repair
0.198 0.801 0.000
G11.2 Late-onset cerebellar ataxia
0.198 0.801 0.000
G11.1 Early-onset cerebellar ataxia
0.198 0.801 0.000
G11.0 Congenital nonprogressive ataxia
0.198 0.801 0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.198 0.801 0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.198 0.801 0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.198 0.801 0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.198 0.801 0.000
G40.9 Epilepsy, unspecified
0.199 0.801 0.000
G12.9 Spinal muscular atrophy, unspecified
0.198 0.802 0.000
G12.8 Other spinal muscular atrophies and related syndromes
0.198 0.802 0.000
G12.1 Other inherited spinal muscular atrophy
0.198 0.802 0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.198 0.802 0.000
G12.2 Motor neuron disease
0.197 0.803 0.000
G93 Other disorders of brain
0.196 0.804 0.000
G41.9 Status epilepticus, unspecified
0.193 0.807 0.000
G90.2 Horner's syndrome
0.192 0.808 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.808 0.191
G45.3 Amaurosis fugax
0.191 0.809 0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.189 0.810 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.189 0.810 0.000
G43 Migraine
0.189 0.811 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.183 0.816 0.000
G44.8 Other specified headache syndromes
0.182 0.818 0.000
G03.9 Meningitis, unspecified
0.181 0.819 0.000
G91.9 Hydrocephalus, unspecified
0.181 0.819 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.180 0.819 0.000
J09-J18 Influenza and pneumonia
0.180 0.820 0.000
G61.8 Other inflammatory polyneuropathies
0.180 0.820 0.000
G61.0 Guillain-Barre syndrome
0.178 0.822 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.176 0.824 0.000
G47 Sleep disorders
0.175 0.825 0.000
G41.8 Other status epilepticus
0.174 0.825 0.000
G41.2 Complex partial status epilepticus
0.174 0.825 0.000
G41.1 Petit mal status epilepticus
0.174 0.825 0.000
G41.0 Grand mal status epilepticus
0.174 0.825 0.000
G31.2 Degeneration of nervous system due to alcohol
0.174 0.826 0.000
E53 Deficiency of other B group vitamins
0.001 0.828 0.171
J13 Pneumonia due to Streptococcus pneumoniae
0.172 0.828 0.000
G20 Parkinson's disease
0.170 0.830 0.000
G44.0 Cluster headache syndrome
0.168 0.831 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.168 0.832 0.000
G61.1 Serum neuropathy
0.168 0.832 0.000
E50.9 Vitamin A deficiency, unspecified
0.001 0.832 0.167

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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