TreeWAS – Variant ID: rs1004467

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I20.0 Unstable angina	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.014	0.986
I10 Essential (primary) hypertension	0.000	0.018	0.982
I25.1 Atherosclerotic heart disease	0.000	0.019	0.981
I24 Other acute ischaemic heart diseases	0.000	0.021	0.979
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.025	0.975
I25.2 Old myocardial infarction	0.000	0.027	0.973
I21 Acute myocardial infarction	0.000	0.064	0.936
I10-I15 Hypertensive diseases	0.000	0.066	0.934
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.083	0.917
I22 Subsequent myocardial infarction	0.000	0.092	0.908
Chapter IX Diseases of the circulatory system	0.000	0.093	0.907
I21.4 Acute subendocardial myocardial infarction	0.000	0.103	0.897
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.105	0.895
I24.8 Other forms of acute ischaemic heart disease	0.000	0.110	0.890
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.156	0.844
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.174	0.826
I60-I69 Cerebrovascular diseases	0.000	0.182	0.818
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.196	0.804
I20.1 Angina pectoris with documented spasm	0.000	0.200	0.800
I25.4 Coronary artery aneurysm	0.000	0.218	0.782
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.218	0.782
I69 Sequelae of cerebrovascular disease	0.000	0.224	0.776
I15 Secondary hypertension	0.000	0.226	0.774
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.269	0.731
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.287	0.713
I25.3 Aneurysm of heart	0.000	0.291	0.709
I22.8 Subsequent myocardial infarction of other sites	0.000	0.295	0.705
I24.1 Dressler's syndrome	0.000	0.298	0.702
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.308	0.692
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.315	0.685
I25.5 Ischaemic cardiomyopathy	0.000	0.321	0.678
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.329	0.671
I13 Hypertensive heart and renal disease	0.000	0.330	0.670
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.331	0.669
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.338	0.662
I15.1 Hypertension secondary to other renal disorders	0.000	0.341	0.659
I23 Certain current complications following acute myocardial infarction	0.000	0.346	0.654
I69.3 Sequelae of cerebral infarction	0.000	0.349	0.651
I00-I02 Acute rheumatic fever	0.000	0.350	0.650
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.360	0.640
I65.2 Occlusion and stenosis of carotid artery	0.000	0.376	0.624
I62 Other nontraumatic intracranial haemorrhage	0.000	0.377	0.623
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.382	0.618
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.388	0.612
I11 Hypertensive heart disease	0.000	0.402	0.598
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.414	0.586
I63 Cerebral infarction	0.000	0.415	0.585
I60 Subarachnoid haemorrhage	0.000	0.443	0.557
I15.9 Seconday hypertension, unspecified	0.000	0.445	0.555
I15.8 Other secondary hypertension	0.000	0.445	0.555
I15.2 Hypertension secondary to endocrine disorders	0.000	0.445	0.555
I15.0 Renovascular hypertension	0.000	0.445	0.555
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.478	0.521
I12 Hypertensive renal disease	0.000	0.478	0.522
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.479	0.521
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.504	0.496
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.504	0.496
I65.1 Occlusion and stenosis of basilar artery	0.000	0.504	0.496
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.508	0.492
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.509	0.491
I67 Other cerebrovascular diseases	0.000	0.514	0.486
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.516	0.484
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.519	0.481
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.519	0.480
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.519	0.480
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.519	0.480
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.519	0.480
I21.9 Acute myocardial infarction, unspecified	0.000	0.524	0.476
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.524	0.476
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.525	0.475
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.531	0.469
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.531	0.469
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.531	0.469
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.531	0.469
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.531	0.469
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.531	0.469
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.531	0.469
I02 Rheumatic chorea	0.000	0.534	0.466
I01 Rheumatic fever with heart involvement	0.000	0.534	0.466
I00 Rheumatic fever without mention of heart involvement	0.000	0.534	0.466
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.540	0.459
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.541	0.459
I62.1 Nontraumatic extradural haemorrhage	0.000	0.553	0.447
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.561	0.439
I60.8 Other subarachnoid haemorrhage	0.000	0.563	0.437
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.564	0.436
I67.1 Cerebral aneurysm, nonruptured	0.000	0.565	0.435
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.569	0.431
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.571	0.429
I63.8 Other cerebral infarction	0.000	0.574	0.426
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.579	0.420
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.579	0.420
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.579	0.420
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.579	0.420
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.579	0.420
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.579	0.420
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.579	0.420
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.580	0.420
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.580	0.420
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.580	0.420
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.584	0.416
I23.8 Other current complications following acute myocardial infarction	0.000	0.594	0.405
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.601	0.399
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.601	0.399
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.601	0.399
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.601	0.399
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.601	0.399
I12.9 Hypertensive renal disease without renal failure	0.000	0.612	0.388
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.614	0.386
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.626	0.374
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.626	0.374
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.626	0.374
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.627	0.373
I99 Other and unspecified disorders of circulatory system	0.000	0.629	0.371
I67.2 Cerebral atherosclerosis	0.000	0.641	0.359
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.643	0.356
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.647	0.352
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.651	0.349
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.651	0.349
I67.5 Moyamoya disease	0.000	0.651	0.349
I67.4 Hypertensive encephalopathy	0.000	0.651	0.349
I67.3 Progressive vascular leukoencephalopathy	0.000	0.651	0.349
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.651	0.349
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.666	0.334
I01.8 Other acute rheumatic heart disease	0.000	0.666	0.334
I01.2 Acute rheumatic myocarditis	0.000	0.666	0.334
I01.1 Acute rheumatic endocarditis	0.000	0.666	0.334
I01.0 Acute rheumatic pericarditis	0.000	0.666	0.334
I02.9 Rheumatic chorea without heart involvement	0.000	0.666	0.334
I02.0 Rheumatic chorea with heart involvement	0.000	0.666	0.334
I68.0 Cerebral amyloid angiopathy	0.001	0.690	0.309
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.717	0.283
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.727	0.272
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.001	0.727	0.272
I05-I09 Chronic rheumatic heart diseases	0.000	0.728	0.272
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.744	0.256
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.747	0.253
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.747	0.253
I98.0 Cardiovascular syphilis	0.000	0.747	0.253
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.757	0.242
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.766	0.234
I20.8 Other forms of angina pectoris	0.000	0.768	0.231
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.781	0.219
I67.8 Other specified cerebrovascular diseases	0.000	0.789	0.211
I97.9 Postprocedural disorder of circulatory system, unspecified	0.001	0.804	0.195
I97.0 Postcardiotomy syndrome	0.001	0.804	0.195
I77 Other disorders of arteries and arterioles	0.000	0.804	0.196
I09 Other rheumatic heart diseases	0.000	0.805	0.195
I06 Rheumatic aortic valve diseases	0.000	0.805	0.195
I12.0 Hypertensive renal disease with renal failure	0.000	0.806	0.194
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.815	0.185
I07 Rheumatic tricuspid valve diseases	0.000	0.818	0.182
I77.1 Stricture of artery	0.000	0.821	0.179
I61 Intracerebral haemorrhage	0.002	0.823	0.175
I28 Other diseases of pulmonary vessels	0.001	0.829	0.171
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.831	0.169
I71 Aortic aneurysm and dissection	0.000	0.835	0.165
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.841	0.158
I70 Atherosclerosis	0.000	0.847	0.153
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.850	0.150
I78 Diseases of capillaries	0.000	0.854	0.145
I77.6 Arteritis, unspecified	0.000	0.855	0.145
I97.1 Other functional disturbances following cardiac surgery	0.001	0.857	0.143
I67.9 Cerebrovascular disease, unspecified	0.000	0.858	0.142
I77.5 Necrosis of artery	0.000	0.859	0.141
I77.4 Coeliac artery compression syndrome	0.000	0.859	0.141
I77.3 Arterial fibromuscular dysplasia	0.000	0.859	0.141
I77.2 Rupture of artery	0.000	0.859	0.141
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.860	0.140
I06.8 Other rheumatic aortic valve diseases	0.000	0.860	0.140
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.860	0.140
I06.1 Rheumatic aortic insufficiency	0.000	0.860	0.140
I06.0 Rheumatic aortic stenosis	0.000	0.860	0.140
I09.9 Rheumatic heart disease, unspecified	0.000	0.860	0.140
I09.8 Other specified rheumatic heart diseases	0.000	0.860	0.140
I09.2 Chronic rheumatic pericarditis	0.000	0.860	0.140
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.860	0.140
I09.0 Rheumatic myocarditis	0.000	0.860	0.140
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.860	0.140
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.863	0.137
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.864	0.136
I71.0 Dissection of aorta [any part]	0.000	0.864	0.136
I05 Rheumatic mitral valve diseases	0.001	0.865	0.134
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.867	0.133
I79.1 Aortitis in diseases classified elsewhere	0.000	0.867	0.133
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.867	0.133
I07.9 Tricuspid valve disease, unspecified	0.000	0.869	0.130
I07.8 Other tricuspid valve diseases	0.000	0.869	0.130
I07.2 Tricuspid stenosis with insufficiency	0.000	0.869	0.130
I07.0 Tricuspid stenosis	0.000	0.869	0.130
I77.8 Other specified disorders of arteries and arterioles	0.000	0.869	0.131
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.870	0.129
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.001	0.871	0.127
I27 Other pulmonary heart diseases	0.001	0.872	0.127
I61.6 Intracerebral haemorrhage, multiple localised	0.002	0.873	0.125
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.874	0.126
Z95.2 Presence of prosthetic heart valve	0.000	0.877	0.123
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.877	0.122
I28.1 Aneurysm of pulmonary artery	0.001	0.877	0.122
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.877	0.122
I74 Arterial embolism and thrombosis	0.000	0.877	0.123
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.002	0.880	0.119
I77.0 Arteriovenous fistula, acquired	0.000	0.880	0.120
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.881	0.118
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.882	0.118
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.882	0.118
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.882	0.118
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.882	0.118
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.882	0.118
I07.1 Tricuspid insufficiency	0.000	0.882	0.117
I61.4 Intracerebral haemorrhage in cerebellum	0.002	0.887	0.111
I61.8 Other intracerebral haemorrhage	0.002	0.889	0.110
I70.9 Generalised and unspecified atherosclerosis	0.000	0.890	0.110
I70.8 Atherosclerosis of other arteries	0.000	0.890	0.110
I70.1 Atherosclerosis of renal artery	0.000	0.890	0.110
Z95.3 Presence of xenogenic heart valve	0.000	0.892	0.108
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.894	0.106
I70.0 Atherosclerosis of aorta	0.000	0.894	0.105
I78.9 Disease of capillaries, unspecified	0.000	0.895	0.104
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.897	0.103
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.899	0.101
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.899	0.101
I78.8 Other diseases of capillaries	0.000	0.899	0.100
I05.1 Rheumatic mitral insufficiency	0.000	0.901	0.099
I28.8 Other specified diseases of pulmonary vessels	0.001	0.901	0.098
I05.8 Other mitral valve diseases	0.001	0.903	0.096
I72 Other aneurysm	0.000	0.903	0.096
I74.5 Embolism and thrombosis of iliac artery	0.000	0.904	0.096
I27.0 Primary pulmonary hypertension	0.000	0.905	0.095
I27.8 Other specified pulmonary heart diseases	0.000	0.905	0.094
I63.9 Cerebral infarction, unspecified	0.000	0.908	0.092
I27.1 Kyphoscoliotic heart disease	0.001	0.908	0.091
Z95.4 Presence of other heart-valve replacement	0.000	0.909	0.091
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.909	0.089
Z95.0 Presence of cardiac pacemaker	0.000	0.910	0.090
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.910	0.090
I26 Pulmonary embolism	0.001	0.910	0.089
I78.1 Naevus, nonneoplastic	0.000	0.911	0.089
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.912	0.088
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.912	0.088
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.912	0.088
I05.9 Mitral valve disease, unspecified	0.001	0.912	0.087
I74.8 Embolism and thrombosis of other arteries	0.000	0.914	0.086
I05.2 Mitral stenosis with insufficiency	0.001	0.919	0.081
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.921	0.079
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.921	0.079
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.921	0.079
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.921	0.079
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.921	0.079
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.921	0.079
I72.0 Aneurysm of carotid artery	0.000	0.922	0.078
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.922	0.078
I27.9 Pulmonary heart disease, unspecified	0.001	0.924	0.075
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.924	0.076
I05.0 Mitral stenosis	0.001	0.926	0.073
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.927	0.073
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.927	0.072
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.927	0.072
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.929	0.071
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.931	0.069
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.931	0.069
I72.1 Aneurysm of artery of upper extremity	0.000	0.931	0.069
I72.8 Aneurysm of other specified arteries	0.000	0.933	0.067
I72.2 Aneurysm of renal artery	0.000	0.935	0.064
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.937	0.063
I95 Hypotension	0.001	0.937	0.062
I72.9 Aneurysm of unspecified site	0.000	0.940	0.060
I08 Multiple valve diseases	0.001	0.945	0.054
I30-I52 Other forms of heart disease	0.000	0.948	0.052
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.001	0.949	0.050
I72.4 Aneurysm of artery of lower extremity	0.000	0.950	0.049
I45 Other conduction disorders	0.000	0.952	0.048
I44 Atrioventricular and left bundle-branch block	0.000	0.952	0.048
I72.3 Aneurysm of iliac artery	0.001	0.952	0.047
I73 Other peripheral vascular diseases	0.000	0.954	0.046
I50 Heart failure	0.000	0.954	0.046
I95.8 Other hypotension	0.001	0.954	0.044
I95.0 Idiopathic hypotension	0.001	0.954	0.044
I45.1 Other and unspecified right bundle-branch block	0.000	0.955	0.045
I44.1 Atrioventricular block, second degree	0.000	0.956	0.044
I44.7 Left bundle-branch block, unspecified	0.000	0.956	0.044
I50.1 Left ventricular failure	0.000	0.957	0.043
Z95.1 Presence of aortocoronary bypass graft	0.000	0.957	0.043
I61.9 Intracerebral haemorrhage, unspecified	0.003	0.957	0.040
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.958	0.042
R07.4 Chest pain, unspecified	0.000	0.959	0.041
I27.2 Other secondary pulmonary hypertension	0.001	0.959	0.040
I45.2 Bifascicular block	0.000	0.960	0.040
I08.9 Multiple valve disease, unspecified	0.001	0.960	0.039
I45.6 Preexcitation syndrome	0.000	0.961	0.039
I44.0 Atrioventricular block, first degree	0.000	0.961	0.039
I46 Cardiac arrest	0.000	0.962	0.038
I52 Other heart disorders in diseases classified elsewhere	0.000	0.963	0.037
I48 Atrial fibrillation and flutter	0.000	0.963	0.037
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.963	0.037
I41 Myocarditis in diseases classified elsewhere	0.000	0.963	0.037
I40 Acute myocarditis	0.000	0.963	0.037
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.963	0.037
I32 Pericarditis in diseases classified elsewhere	0.000	0.963	0.037
I44.6 Other and unspecified fascicular block	0.000	0.964	0.036
I36 Nonrheumatic tricuspid valve disorders	0.000	0.964	0.036
I45.3 Trifascicular block	0.000	0.964	0.036
I37 Pulmonary valve disorders	0.000	0.965	0.035
I33 Acute and subacute endocarditis	0.000	0.965	0.035
I45.0 Right fascicular block	0.000	0.965	0.035
I44.5 Left posterior fascicular block	0.000	0.965	0.035
I45.4 Nonspecific intraventricular block	0.000	0.966	0.034
I95.2 Hypotension due to drugs	0.001	0.966	0.033
I08.8 Other multiple valve diseases	0.001	0.966	0.033
I45.8 Other specified conduction disorders	0.000	0.966	0.033
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.967	0.033
I50.0 Congestive heart failure	0.000	0.967	0.033
I44.3 Other and unspecified atrioventricular block	0.000	0.968	0.032
I73.8 Other specified peripheral vascular diseases	0.000	0.968	0.031
I45.5 Other specified heart block	0.000	0.969	0.031
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.969	0.030
I46.0 Cardiac arrest with successful resuscitation	0.000	0.970	0.030
I31 Other diseases of pericardium	0.000	0.972	0.028
I45.9 Conduction disorder, unspecified	0.000	0.972	0.028
I46.1 Sudden cardiac death, so described	0.000	0.973	0.027
I30 Acute pericarditis	0.000	0.973	0.027
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.973	0.027
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.973	0.027
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.973	0.027
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.973	0.027
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.973	0.027
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.973	0.027
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.973	0.027
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.973	0.027
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.973	0.027
I40.9 Acute myocarditis, unspecified	0.000	0.973	0.027
I40.8 Other acute myocarditis	0.000	0.973	0.027
I40.1 Isolated myocarditis	0.000	0.973	0.027
I40.0 Infective myocarditis	0.000	0.973	0.027
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.973	0.027
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.973	0.027
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.973	0.027
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.973	0.027
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.973	0.027
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.973	0.027
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.973	0.027
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.973	0.027
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.973	0.027
I48.4 Atypical atrial flutter	0.000	0.973	0.027
I48.3 Typical atrial flutter	0.000	0.973	0.027
I48.2 Chronic atrial fibrillation	0.000	0.973	0.027
I48.1 Persistent atrial fibrillation	0.000	0.973	0.027
I48.0 Paroxysmal atrial fibrillation	0.000	0.973	0.027
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.973	0.027
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.973	0.027
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.973	0.027
I44.4 Left anterior fascicular block	0.000	0.973	0.026
I50.9 Heart failure, unspecified	0.000	0.974	0.026
I38 Endocarditis, valve unspecified	0.000	0.974	0.026
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.974	0.026
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.974	0.026
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.974	0.026
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.974	0.026
I42 Cardiomyopathy	0.000	0.975	0.025
I37.9 Pulmonary valve disorder, unspecified	0.000	0.975	0.025
I37.8 Other pulmonary valve disorders	0.000	0.975	0.025
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.975	0.025
I37.0 Pulmonary valve stenosis	0.000	0.975	0.025
I33.9 Acute endocarditis, unspecified	0.000	0.975	0.025
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.975	0.025
I35 Nonrheumatic aortic valve disorders	0.000	0.975	0.025
I46.9 Cardiac arrest, unspecified	0.000	0.975	0.025
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.976	0.024
I44.2 Atrioventricular block, complete	0.000	0.976	0.024
I37.1 Pulmonary valve insufficiency	0.000	0.977	0.023
I33.0 Acute and subacute infective endocarditis	0.000	0.977	0.023
I49 Other cardiac arrhythmias	0.000	0.979	0.021
I31.8 Other specified diseases of pericardium	0.000	0.979	0.021
I31.2 Haemopericardium, not elsewhere classified	0.000	0.979	0.021
I31.1 Chronic constrictive pericarditis	0.000	0.979	0.021
I31.0 Chronic adhesive pericarditis	0.000	0.979	0.021
I42.6 Alcoholic cardiomyopathy	0.000	0.979	0.021
I49.0 Ventricular fibrillation and flutter	0.000	0.980	0.020
I42.0 Dilated cardiomyopathy	0.000	0.980	0.020
I30.8 Other forms of acute pericarditis	0.000	0.980	0.019
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.980	0.019
I35.9 Aortic valve disorder, unspecified	0.000	0.981	0.019
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.981	0.018
I42.5 Other restrictive cardiomyopathy	0.000	0.981	0.018
I42.4 Endocardial fibroelastosis	0.000	0.981	0.018
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.981	0.018
I35.1 Aortic (valve) insufficiency	0.000	0.982	0.018
I31.3 Pericardial effusion (noninflammatory)	0.000	0.982	0.018
I42.2 Other hypertrophic cardiomyopathy	0.000	0.983	0.017
I30.1 Infective pericarditis	0.000	0.983	0.017
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.983	0.016
I35.0 Aortic (valve) stenosis	0.000	0.984	0.016
I31.9 Disease of pericardium, unspecified	0.000	0.984	0.016
R07 Pain in throat and chest	0.000	0.984	0.016
I49.2 Junctional premature depolarisation	0.000	0.984	0.015
I49.1 Atrial premature depolarisation	0.000	0.985	0.015
R22.4 Localised swelling, mass and lump, lower limb	0.015	0.985	0.000
R22.1 Localised swelling, mass and lump, neck	0.014	0.986	0.000
G40.9 Epilepsy, unspecified	0.000	0.986	0.014
I30.9 Acute pericarditis, unspecified	0.000	0.986	0.014
R07.2 Precordial pain	0.000	0.986	0.014
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.014	0.986	0.000
I35.8 Other aortic valve disorders	0.000	0.986	0.014
G40 Epilepsy	0.000	0.986	0.014
I42.8 Other cardiomyopathies	0.000	0.987	0.013
R07.0 Pain in throat	0.000	0.987	0.013
I95.1 Orthostatic hypotension	0.001	0.987	0.012
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.987	0.013
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.987	0.013
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.013	0.987	0.000
R22.0 Localised swelling, mass and lump, head	0.013	0.987	0.000
I47 Paroxysmal tachycardia	0.000	0.987	0.013
I49.8 Other specified cardiac arrhythmias	0.000	0.987	0.012
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.012	0.988	0.000
I49.4 Other and unspecified premature depolarisation	0.000	0.988	0.012
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.988	0.012
I42.9 Cardiomyopathy, unspecified	0.000	0.988	0.012
I49.9 Cardiac arrhythmia, unspecified	0.000	0.988	0.012
I08.0 Disorders of both mitral and aortic valves	0.001	0.988	0.011
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.012	0.988	0.000
I49.5 Sick sinus syndrome	0.000	0.988	0.012
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.988	0.012
R22.2 Localised swelling, mass and lump, trunk	0.012	0.988	0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.011	0.989	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.989	0.011
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.011	0.989	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.011	0.989	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.990	0.010
R22.7 Localised swelling, mass and lump, multiple sites	0.010	0.990	0.000
G40.8 Other epilepsy	0.000	0.990	0.010
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.990	0.010
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.990	0.010
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.990	0.010
I87 Other disorders of veins	0.000	0.990	0.010
K62.0 Anal polyp	0.010	0.990	0.000
M25.46 Effusion of joint (Lower leg)	0.010	0.990	0.000
G40.5 Special epileptic syndromes	0.000	0.991	0.009
I88 Nonspecific lymphadenitis	0.000	0.991	0.009
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.009	0.991	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.009	0.991	0.000
I87.1 Compression of vein	0.000	0.991	0.008
I49.3 Ventricular premature depolarisation	0.000	0.991	0.008
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.992	0.008
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.992	0.008
I82 Other venous embolism and thrombosis	0.000	0.992	0.008
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.992	0.008
I47.0 Reentry ventricular arrhythmia	0.000	0.992	0.008
M07.39 Other psoriatic arthropathies (Site unspecified)	0.008	0.992	0.000
C20 Malignant neoplasm of rectum	0.008	0.992	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.992	0.008
M07.3 Other psoriatic arthropathies	0.008	0.992	0.000
I81 Portal vein thrombosis	0.000	0.992	0.007
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.007	0.992	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.008	0.992	0.000
I86 Varicose veins of other sites	0.000	0.992	0.007
I87.9 Disorder of vein, unspecified	0.000	0.993	0.007
I87.0 Postphlebitic syndrome	0.000	0.993	0.007
I89.1 Lymphangitis	0.000	0.993	0.007
M07.36 Other psoriatic arthropathies (Lower leg)	0.007	0.993	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.993	0.007
R22.9 Localised swelling, mass and lump, unspecified	0.007	0.993	0.000
I47.2 Ventricular tachycardia	0.000	0.993	0.007
I88.8 Other nonspecific lymphadenitis	0.000	0.993	0.007
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.993	0.007
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.993	0.007
M07.34 Other psoriatic arthropathies (Hand)	0.007	0.993	0.000
I51.4 Myocarditis, unspecified	0.000	0.993	0.007
I73.0 Raynaud's syndrome	0.000	0.993	0.007
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.993	0.006
R07.1 Chest pain on breathing	0.000	0.993	0.006
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.993	0.006
M07.30 Other psoriatic arthropathies (Multiple sites)	0.006	0.993	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.994	0.006
R07.3 Other chest pain	0.000	0.994	0.006
M65.9 Synovitis and tenosynovitis, unspecified	0.006	0.994	0.000
I82.3 Embolism and thrombosis of renal vein	0.000	0.994	0.006
I82.1 Thrombophlebitis migrans	0.000	0.994	0.006
I82.0 Budd-Chiari syndrome	0.000	0.994	0.006
G40-G47 Episodic and paroxysmal disorders	0.000	0.994	0.006
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.006	0.994	0.000
G45.3 Amaurosis fugax	0.000	0.994	0.006
H52.1 Myopia	0.006	0.994	0.000
F31 Bipolar affective disorder	0.000	0.994	0.006
I51.5 Myocardial degeneration	0.000	0.994	0.006
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.994	0.006
I51.0 Cardiac septal defect, acquired	0.000	0.994	0.006
I73.9 Peripheral vascular disease, unspecified	0.000	0.994	0.006
I82.2 Embolism and thrombosis of vena cava	0.000	0.994	0.006
M07.38 Other psoriatic arthropathies (Other)	0.006	0.994	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.006	0.994	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.006	0.994	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.006	0.994	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations