TreeWAS – Variant ID: rs10091038

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.286	0.714
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.304	0.696
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.314	0.686
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.330	0.670
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.351	0.649
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.364	0.636
T42.4 Benzodiazepines	0.000	0.371	0.629
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.374	0.626
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.399	0.601
T43.2 Other and unspecified antidepressants	0.000	0.399	0.601
T43.6 Psychostimulants with abuse potential	0.000	0.419	0.581
T46.1 Calcium-channel blockers	0.000	0.428	0.572
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.429	0.571
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.466	0.534
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.483	0.517
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.488	0.512
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.491	0.509
T43.9 Psychotropic drug, unspecified	0.000	0.494	0.506
T42.3 Barbiturates	0.000	0.511	0.489
T42.1 Iminostilbenes	0.000	0.522	0.478
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.523	0.477
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.535	0.465
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.538	0.462
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.541	0.459
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.541	0.459
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.544	0.456
T42.2 Succinimides and oxazolidinediones	0.000	0.544	0.456
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.546	0.454
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.550	0.450
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.551	0.448
T46.7 Peripheral vasodilators	0.000	0.551	0.448
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.552	0.448
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.560	0.440
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.569	0.431
T42.0 Hydantoin derivatives	0.000	0.571	0.429
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.573	0.427
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.576	0.424
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.578	0.422
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.585	0.415
T36 Poisoning by systemic antibiotics	0.000	0.596	0.404
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.600	0.400
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.601	0.399
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.602	0.398
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.606	0.394
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.612	0.388
T38.9 Other and unspecified hormone antagonists	0.000	0.617	0.383
T38.7 Androgens and anabolic congeners	0.000	0.617	0.383
T38.5 Other oestrogens and progestogens	0.000	0.617	0.383
T38.4 Oral contraceptives	0.000	0.617	0.383
T38.2 Antithyroid drugs	0.000	0.617	0.383
T38.1 Thyroid hormones and substitutes	0.000	0.618	0.382
T38.0 Glucocorticoids and synthetic analogues	0.000	0.623	0.377
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.631	0.368
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.646	0.354
T47.6 Antidiarrhoeal drugs	0.000	0.655	0.345
T49.9 Topical agent, unspecified	0.000	0.658	0.342
T49.8 Other topical agents	0.000	0.658	0.342
T49.7 Dental drugs, topically applied	0.000	0.658	0.342
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.658	0.342
T49.5 Ophthalmological drugs and preparations	0.000	0.658	0.342
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.658	0.342
T49.3 Emollients, demulcents and protectants	0.000	0.658	0.342
T49.2 Local astringents and local detergents	0.000	0.658	0.342
T49.1 Antipruritics	0.000	0.658	0.342
T40.6 Other and unspecified narcotics	0.000	0.661	0.339
T47.0 Histamine H(2)-receptor antagonists	0.000	0.664	0.336
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.665	0.335
T41.5 Therapeutic gases	0.000	0.666	0.334
T41.4 Anaesthetic, unspecified	0.000	0.666	0.334
T41.3 Local anaesthetics	0.000	0.666	0.334
T41.2 Other and unspecified general anaesthetics	0.000	0.666	0.334
T41.1 Intravenous anaesthetics	0.000	0.666	0.334
T41.0 Inhaled anaesthetics	0.000	0.666	0.334
T36.0 Penicillins	0.000	0.670	0.330
Z02.8 Other examinations for administrative purposes	0.000	0.670	0.330
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.677	0.323
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.677	0.323
T47.7 Emetics	0.000	0.677	0.323
T47.5 Digestants	0.000	0.677	0.323
T47.3 Saline and osmotic laxatives	0.000	0.677	0.323
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.678	0.321
T37.5 Antiviral drugs	0.000	0.678	0.321
T37.4 Anthelminthics	0.000	0.678	0.321
T37.3 Other antiprotozoal drugs	0.000	0.678	0.321
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.678	0.321
T37.1 Antimycobacterial drugs	0.000	0.678	0.321
T37.0 Sulphonamides	0.000	0.678	0.321
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.679	0.321
T40.4 Other synthetic narcotics	0.000	0.681	0.319
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.684	0.316
T48.4 Expectorants	0.000	0.684	0.316
T48.3 Antitussives	0.000	0.684	0.316
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.684	0.316
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.684	0.316
T48.0 Oxytocic drugs	0.000	0.684	0.316
T48.5 Anti-common-cold drugs	0.000	0.686	0.314
T40.1 Heroin	0.000	0.687	0.313
T45.5 Anticoagulants	0.000	0.689	0.311
T47.4 Other laxatives	0.000	0.691	0.309
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.695	0.304
T50.4 Drugs affecting uric acid metabolism	0.000	0.697	0.303
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.697	0.303
T40.8 Lysergide [LSD]	0.000	0.697	0.303
T40.7 Cannabis (derivatives)	0.000	0.697	0.303
T40.3 Methadone	0.000	0.697	0.303
T40.0 Opium	0.000	0.697	0.303
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.705	0.295
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.707	0.293
T40.5 Cocaine	0.000	0.708	0.291
T45.2 Vitamins, not elsewhere classified	0.000	0.709	0.291
T36.9 Systemic antibiotic, unspecified	0.000	0.710	0.290
T36.7 Antifungal antibiotics, systemically used	0.000	0.710	0.290
T36.6 Rifamycins	0.000	0.710	0.290
T36.5 Aminoglycosides	0.000	0.710	0.290
T36.2 Chloramphenicol group	0.000	0.710	0.290
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.710	0.290
T50.7 Analeptics and opioid receptor antagonists	0.000	0.713	0.287
T50.5 Appetite depressants	0.000	0.713	0.287
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.713	0.287
T50.0 Mineralocorticoids and their antagonists	0.000	0.713	0.287
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.717	0.282
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.717	0.282
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.717	0.282
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.717	0.282
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.717	0.282
T44.0 Anticholinesterase agents	0.000	0.717	0.282
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.718	0.282
T47.2 Stimulant laxatives	0.000	0.718	0.282
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.721	0.279
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.722	0.278
T45.8 Other primarily systemic and haematological agents	0.000	0.722	0.278
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.722	0.278
T45.6 Fibrinolysis-affecting drugs	0.000	0.722	0.278
T45.4 Iron and its compounds	0.000	0.722	0.278
T45.3 Enzymes, not elsewhere classified	0.000	0.722	0.278
T36.8 Other systemic antibiotics	0.000	0.726	0.274
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.752	0.248
T50.1 Loop [high-ceiling] diuretics	0.000	0.753	0.246
T50.8 Diagnostic agents	0.000	0.755	0.245
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.757	0.243
T36.3 Macrolides	0.000	0.759	0.240
T36.4 Tetracyclines	0.000	0.760	0.239
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.764	0.236
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.772	0.228
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.783	0.217
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.783	0.216
T45.0 Antiallergic and antiemetic drugs	0.000	0.819	0.181
T39.4 Antirheumatics, not elsewhere classified	0.000	0.825	0.174
T39.2 Pyrazolone derivatives	0.000	0.825	0.174
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.831	0.169
T40.2 Other opioids	0.000	0.848	0.152
Z02 Examination and encounter for administrative purposes	0.000	0.862	0.138
T39.0 Salicylates	0.000	0.882	0.118
Z02.9 Examination for administrative purposes, unspecified	0.000	0.901	0.099
Z02.7 Issue of medical certificate	0.000	0.901	0.099
Z02.6 Examination for insurance purposes	0.000	0.901	0.099
Z02.5 Examination for participation in sport	0.000	0.901	0.099
Z02.4 Examination for driving licence	0.000	0.901	0.099
Z02.3 Examination for recruitment to armed forces	0.000	0.901	0.099
Z02.2 Examination for admission to residential institution	0.000	0.901	0.099
Z02.1 Pre-employment examination	0.000	0.901	0.099
Z02.0 Examination for admission to educational institution	0.000	0.901	0.099
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.912	0.088
T39.1 4-Aminophenol derivatives	0.000	0.923	0.077
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.043	0.957	0.000
M85.8 Other specified disorders of bone density and structure	0.043	0.957	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.040	0.960	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.036	0.964	0.000
M85 Other disorders of bone density and structure	0.033	0.966	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.033	0.967	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.032	0.968	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.032	0.968	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.031	0.969	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.031	0.969	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.030	0.970	0.000
M85.0 Fibrous dysplasia (monostotic)	0.029	0.970	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.029	0.971	0.000
M85.4 Solitary bone cyst	0.026	0.973	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.026	0.974	0.000
M85.2 Hyperostosis of skull	0.026	0.974	0.000
M85.6 Other cyst of bone	0.026	0.974	0.000
M85.9 Disorder of bone density and structure, unspecified	0.025	0.975	0.000
M85.5 Aneurysmal bone cyst	0.024	0.976	0.000
M85.3 Osteitis condensans	0.024	0.976	0.000
M85.1 Skeletal fluorosis	0.024	0.976	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.023	0.977	0.000
M85.46 Solitary bone cyst (Lower leg)	0.022	0.978	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.021	0.979	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.021	0.979	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.021	0.979	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.021	0.979	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.021	0.979	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.021	0.979	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.021	0.979	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.021	0.979	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.021	0.979	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.021	0.979	0.000
M79.62 Pain in limb (Upper arm)	0.000	0.980	0.020
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.020	0.980	0.000
M85.22 Hyperostosis of skull-Upper arm	0.020	0.980	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.020	0.980	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.980	0.020
M85.49 Solitary bone cyst (Site unspecified)	0.019	0.981	0.000
M85.48 Solitary bone cyst (Other)	0.019	0.981	0.000
M85.44 Solitary bone cyst (Hand)	0.019	0.981	0.000
M85.43 Solitary bone cyst (Forearm)	0.019	0.981	0.000
M85.42 Solitary bone cyst (Upper arm)	0.019	0.981	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.019	0.981	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.019	0.981	0.000
M85.20 Hyperostosis of skull-Mult sites	0.019	0.981	0.000
M85.29 Hyperostosis of skull-Site unspec	0.019	0.981	0.000
M85.28 Hyperostosis of skull-Other	0.019	0.981	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.019	0.981	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.019	0.981	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.019	0.981	0.000
M85.24 Hyperostosis of skull-Hand	0.019	0.981	0.000
M85.23 Hyperostosis of skull-Forearm	0.019	0.981	0.000
M85.21 Hyperostosis of skull-Shldr region	0.019	0.981	0.000
O20.0 Threatened abortion	0.000	0.981	0.019
M85.69 Other cyst of bone (Site unspecified)	0.018	0.981	0.000
M85.63 Other cyst of bone (Forearm)	0.018	0.981	0.000
M85.62 Other cyst of bone (Upper arm)	0.018	0.981	0.000
M85.61 Other cyst of bone (Shoulder region)	0.018	0.981	0.000
M85.60 Other cyst of bone (Multiple sites)	0.018	0.981	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.018	0.981	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.018	0.981	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.018	0.981	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.018	0.981	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.018	0.981	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.018	0.981	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.018	0.981	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.018	0.981	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.018	0.981	0.000
M85.68 Other cyst of bone (Other)	0.018	0.982	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.017	0.982	0.000
M85.18 Skeletal fluorosis (Other)	0.017	0.982	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.017	0.982	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.017	0.982	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.017	0.982	0.000
M85.14 Skeletal fluorosis (Hand)	0.017	0.982	0.000
M85.13 Skeletal fluorosis (Forearm)	0.017	0.982	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.017	0.982	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.017	0.982	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.017	0.982	0.000
M85.39 Osteitis condensans (Site unspecified)	0.017	0.982	0.000
M85.38 Osteitis condensans (Other)	0.017	0.982	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.017	0.982	0.000
M85.36 Osteitis condensans (Lower leg)	0.017	0.982	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.017	0.982	0.000
M85.34 Osteitis condensans (Hand)	0.017	0.982	0.000
M85.33 Osteitis condensans (Forearm)	0.017	0.982	0.000
M85.32 Osteitis condensans (Upper arm)	0.017	0.982	0.000
M85.31 Osteitis condensans (Shoulder region)	0.017	0.982	0.000
M85.30 Osteitis condensans (Multiple sites)	0.017	0.982	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.017	0.982	0.000
M85.58 Aneurysmal bone cyst (Other)	0.017	0.982	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.017	0.982	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.017	0.982	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.017	0.982	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.017	0.982	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.017	0.982	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.017	0.982	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.017	0.982	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.017	0.982	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.017	0.983	0.000
M85.66 Other cyst of bone (Lower leg)	0.017	0.983	0.000
M85.64 Other cyst of bone (Hand)	0.017	0.983	0.000
O20 Haemorrhage in early pregnancy	0.000	0.983	0.017
M22.4 Chondromalacia patellae	0.000	0.984	0.016
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.984	0.016
O20.8 Other haemorrhage in early pregnancy	0.000	0.986	0.014
D47.3 Essential (haemorrhagic) thrombocythaemia	0.010	0.990	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.009	0.991	0.000
D47.1 Chronic myeloproliferative disease	0.009	0.991	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.008	0.991	0.000
D47.4 Osteomyelofibrosis	0.008	0.992	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.992	0.008
S30.2 Contusion of external genital organs	0.000	0.993	0.007
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.993	0.007
D47.2 Monoclonal gammopathy	0.007	0.993	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.006	0.993	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.006	0.993	0.000
F40.2 Specific (isolated) phobias	0.000	0.994	0.006
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.006	0.994	0.000
S30.1 Contusion of abdominal wall	0.000	0.994	0.006
S30.0 Contusion of lower back and pelvis	0.000	0.994	0.006
M13.09 Polyarthritis, unspecified (Site unspecified)	0.006	0.994	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.994	0.006
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.005	0.994	0.000
M94.8 Other specified disorders of cartilage	0.005	0.995	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.000	0.995	0.005
M13.00 Polyarthritis, unspecified (Multiple sites)	0.005	0.995	0.000
F40 Phobic anxiety disorders	0.000	0.995	0.005
M13.0 Polyarthritis, unspecified	0.005	0.995	0.000
F40.8 Other phobic anxiety disorders	0.000	0.995	0.005
M94.89 Other specified disorders of cartilage (Site unspecified)	0.004	0.995	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.996	0.004
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.004	0.996	0.000
F40.9 Phobic anxiety disorder, unspecified	0.000	0.996	0.004
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.004	0.996	0.000
S63.6 Sprain and strain of finger(s)	0.000	0.996	0.004
M94.84 Other specified disorders of cartilage (Hand)	0.004	0.996	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.004	0.996	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.004	0.996	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.004	0.996	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.004	0.996	0.000
F40.0 Agoraphobia	0.000	0.996	0.004
M13.04 Polyarthritis, unspecified (Hand)	0.004	0.996	0.000
F40.1 Social phobias	0.000	0.996	0.004
S92.30 Fracture of metatarsal bone (closed)	0.000	0.996	0.004
M13.06 Polyarthritis, unspecified (Lower leg)	0.004	0.996	0.000
M13.08 Polyarthritis, unspecified (Other)	0.004	0.996	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.004	0.996	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.004	0.996	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.004	0.996	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.004	0.996	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.996	0.004
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.996	0.004
E11.1 With ketoacidosis	0.004	0.996	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.996	0.004
S92.3 Fracture of metatarsal bone	0.000	0.997	0.003
S92.41 Fracture of great toe (open)	0.000	0.997	0.003
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.997	0.003
M94.88 Other specified disorders of cartilage (Other)	0.003	0.997	0.000
S92.4 Fracture of great toe	0.000	0.997	0.003
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.997	0.003
O21 Excessive vomiting in pregnancy	0.000	0.997	0.003
O28 Abnormal findings on antenatal screening of mother	0.000	0.997	0.003
S92 Fracture of foot, except ankle	0.000	0.997	0.003
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.997	0.003
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.997	0.003
H61.8 Other specified disorders of external ear	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.997	0.003
H80.9 Otosclerosis, unspecified	0.003	0.997	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.003	0.997	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.997	0.003
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.997	0.003
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.997	0.003
O29 Complications of anaesthesia during pregnancy	0.000	0.997	0.003
O25 Malnutrition in pregnancy	0.000	0.997	0.003
S92.2 Fracture of other tarsal bone(s)	0.000	0.997	0.003
O72 Postpartum haemorrhage	0.000	0.997	0.003
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.003	0.997	0.000
S92.40 Fracture of great toe (closed)	0.000	0.997	0.003
A69.9 Spirochaetal infection, unspecified	0.003	0.997	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.003	0.997	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.997	0.003
S92.31 Fracture of metatarsal bone (open)	0.000	0.997	0.003
A69.2 Lyme disease	0.003	0.997	0.000
O23 Infections of genito-urinary tract in pregnancy	0.000	0.997	0.003
O22 Venous complications in pregnancy	0.000	0.997	0.003
O21.8 Other vomiting complicating pregnancy	0.000	0.997	0.003
M70.46 Prepatellar bursitis-Lower Leg	0.003	0.997	0.000
S92.5 Fracture of other toe	0.000	0.997	0.003
S92.1 Fracture of talus	0.000	0.997	0.003
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.997	0.002
Z39.1 Care and examination of lactating mother	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.997	0.002
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.997	0.002
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.997	0.002
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.997	0.002
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.997	0.002
S91.1 Open wound of toe(s) without damage to nail	0.000	0.997	0.003
E83.4 Disorders of magnesium metabolism	0.003	0.997	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.997	0.002
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.997	0.002
O24 Diabetes mellitus in pregnancy	0.000	0.997	0.002
S42.40 Fracture of lower end of humerus (closed)	0.000	0.997	0.003
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.003	0.997	0.000
S51.0 Open wound of elbow	0.000	0.997	0.002
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.997	0.003
S37.00 Injury of kidney (without open wound into cavity)	0.000	0.998	0.002
O22.1 Genital varices in pregnancy	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
S92.51 Fracture of other toe (open)	0.000	0.998	0.002
A69 Other spirochaetal infections	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.002	0.998	0.000
O21.2 Late vomiting of pregnancy	0.000	0.998	0.002
O23.0 Infections of kidney in pregnancy	0.000	0.998	0.002
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.998	0.002
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.6 Failed or difficult intubation during pregnancy	0.000	0.998	0.002
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.998	0.002
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.998	0.002
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.998	0.002
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.998	0.002
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.000	0.998	0.002
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.998	0.002
O23.5 Infections of the genital tract in pregnancy	0.000	0.998	0.002
R22.3 Localised swelling, mass and lump, upper limb	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.000	0.998	0.002
H80 Otosclerosis	0.002	0.998	0.000
M22 Disorders of patella	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.000	0.998	0.002
O72.3 Postpartum coagulation defects	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.000	0.998	0.002
F43.0 Acute stress reaction	0.000	0.998	0.002
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.998	0.002
H60 Otitis externa	0.002	0.998	0.000
M94 Other disorders of cartilage	0.002	0.998	0.000
H60.8 Other otitis externa	0.002	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.000	0.998	0.002
O22.9 Venous complication in pregnancy, unspecified	0.000	0.998	0.002
O22.8 Other venous complications in pregnancy	0.000	0.998	0.002
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.998	0.002
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.998	0.002
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.998	0.002
O23.2 Infections of urethra in pregnancy	0.000	0.998	0.002
O23.1 Infections of bladder in pregnancy	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
M80-M85 Disorders of bone density and structure	0.002	0.998	0.001
H60.2 Malignant otitis externa	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.002	0.998	0.000
M22.9 Disorder of patella, unspecified	0.000	0.998	0.002
W44.0 Home	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.000	0.998	0.002
H80.8 Other otosclerosis	0.002	0.998	0.000
S37.0 Injury of kidney	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.000	0.998	0.002
M22.0 Recurrent dislocation of patella	0.000	0.998	0.002
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.998	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.998	0.002
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.998	0.002
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.998	0.002
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.998	0.002
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.002
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.998	0.002
K76.0 Fatty (change of) liver, not elsewhere classified	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.000	0.998	0.002
A69.8 Other specified spirochaetal infections	0.002	0.998	0.000
A69.1 Other Vincent's infections	0.002	0.998	0.000
A69.0 Necrotising ulcerative stomatitis	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.000	0.998	0.002
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
H80.2 Cochlear otosclerosis	0.002	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.000	0.998	0.002
S95 Injury of blood vessels at ankle and foot level	0.000	0.998	0.002
S94 Injury of nerves at ankle and foot level	0.000	0.998	0.002
M22.1 Recurrent subluxation of patella	0.000	0.998	0.002
V23.4 Driver injured in traffic accident	0.000	0.998	0.002
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.998	0.002
S90.0 Contusion of ankle	0.000	0.998	0.002
S37 Injury of urinary and pelvic organs	0.000	0.998	0.002
H80.0 Otosclerosis involving oval window, nonobliterative	0.002	0.998	0.000
M94.3 Chondrolysis	0.002	0.998	0.000
M94.1 Relapsing polychondritis	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.998	0.002
S90.2 Contusion of toe(s) with damage to nail	0.000	0.998	0.002
H61 Other disorders of external ear	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.002
S37.01 Injury of kidney (with open wound into cavity)	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
S05.1 Contusion of eyeball and orbital tissues	0.000	0.998	0.002
S97 Crushing injury of ankle and foot	0.000	0.998	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
H60.0 Abscess of external ear	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.998	0.002
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.000	0.998	0.002
S92.90 Fracture of foot, unspecified (closed)	0.000	0.998	0.001
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
M83 Adult osteomalacia	0.001	0.998	0.001
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
M92.7 Juvenile osteochondrosis of metatarsus	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.998	0.002
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.998	0.002
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.000	0.998	0.001
O22.4 Haemorrhoids in pregnancy	0.001	0.998	0.001
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.000	0.998	0.001
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations