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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1011665
log Bayes Factor = 42.223
Chromosome 6   position 27,332,298  (GRCh37) Explore rs1011665 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E83 Disorders of mineral metabolism
0.000 0.221 0.779
E10 Insulin-dependent diabetes mellitus
0.000 0.231 0.769
E10-E14 Diabetes mellitus
0.000 0.243 0.757
E70-E90 Metabolic disorders
0.000 0.247 0.753
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.248 0.752
E10.5 With peripheral circulatory complications
0.000 0.254 0.746
E88 Other metabolic disorders
0.000 0.263 0.737
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.274 0.726
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.274 0.726
E10.9 Without complications
0.000 0.284 0.716
E16 Other disorders of pancreatic internal secretion
0.000 0.292 0.708
E10.4 With neurological complications
0.000 0.300 0.700
E16.2 Hypoglycaemia, unspecified
0.000 0.303 0.697
E10.8 With unspecified complications
0.000 0.326 0.674
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.355 0.645
E13 Other specified diabetes mellitus
0.000 0.356 0.644
E10.2 With renal complications
0.000 0.381 0.619
E10.6 With other specified complications
0.000 0.407 0.593
E10.7 With multiple complications
0.000 0.413 0.587
E88.3 Tumour lysis syndrome
0.000 0.415 0.585
E13.9 Without complications
0.000 0.422 0.578
E80.4 Gilbert's syndrome
0.000 0.424 0.576
E40-E46 Malnutrition
0.000 0.429 0.571
E84 Cystic fibrosis
0.000 0.437 0.562
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.440 0.560
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.441 0.559
E83.8 Other disorders of mineral metabolism
0.000 0.441 0.559
E83.2 Disorders of zinc metabolism
0.000 0.441 0.559
E83.0 Disorders of copper metabolism
0.000 0.441 0.559
E27.1 Primary adrenocortical insufficiency
0.000 0.444 0.556
E70 Disorders of aromatic amino-acid metabolism
0.000 0.449 0.550
E20-E35 Disorders of other endocrine glands
0.000 0.453 0.547
E27 Other disorders of adrenal gland
0.000 0.454 0.546
E12 Malnutrition-related diabetes mellitus
0.000 0.457 0.542
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.458 0.542
E77 Disorders of glycoprotein metabolism
0.000 0.460 0.540
E76 Disorders of glycosaminoglycan metabolism
0.000 0.460 0.540
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.460 0.540
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.460 0.540
E10.0 With coma
0.000 0.463 0.537
E14 Unspecified diabetes mellitus
0.000 0.469 0.531
E72 Other disorders of amino-acid metabolism
0.000 0.472 0.527
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.473 0.527
E10.3 With ophthalmic complications
0.000 0.475 0.525
E15 Nondiabetic hypoglycaemic coma
0.000 0.479 0.521
E10.1 With ketoacidosis
0.000 0.484 0.516
E88.9 Metabolic disorder, unspecified
0.000 0.488 0.512
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.492 0.508
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.492 0.508
E16.4 Abnormal secretion of gastrin
0.000 0.492 0.508
E16.3 Increased secretion of glucagon
0.000 0.492 0.508
E14.3 With ophthalmic complications
0.000 0.507 0.493
E88.2 Lipomatosis, not elsewhere classified
0.000 0.508 0.492
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.513 0.487
E88.8 Other specified metabolic disorders
0.000 0.514 0.486
E73 Lactose intolerance
0.000 0.523 0.477
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.525 0.475
E80.6 Other disorders of bilirubin metabolism
0.000 0.530 0.470
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.538 0.462
E80.5 Crigler-Najjar syndrome
0.000 0.538 0.462
E80.3 Defects of catalase and peroxydase
0.000 0.538 0.462
E80.1 Porphyria cutanea tarda
0.000 0.538 0.462
E80.0 Hereditary erythropoietic porphyria
0.000 0.538 0.462
E13.8 With unspecified complications
0.000 0.538 0.462
E13.7 With multiple complications
0.000 0.538 0.462
E13.6 With other specified complications
0.000 0.538 0.462
E13.5 With peripheral circulatory complications
0.000 0.538 0.462
E13.4 With neurological complications
0.000 0.538 0.462
E13.2 With renal complications
0.000 0.538 0.462
E13.1 With ketoacidosis
0.000 0.538 0.462
E13.0 With coma
0.000 0.538 0.462
E79 Disorders of purine and pyrimidine metabolism
0.000 0.541 0.459
E65-E68 Obesity and other hyperalimentation
0.000 0.541 0.459
E00-E07 Disorders of thyroid gland
0.000 0.548 0.452
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.553 0.447
E84.9 Cystic fibrosis, unspecified
0.000 0.556 0.444
E46 Unspecified protein-energy malnutrition
0.000 0.559 0.441
E25 Adrenogenital disorders
0.000 0.562 0.438
E20 Hypoparathyroidism
0.000 0.567 0.433
E83.3 Disorders of phosphorus metabolism
0.000 0.570 0.430
E80.2 Other porphyria
0.000 0.570 0.429
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.574 0.426
E13.3 With ophthalmic complications
0.000 0.580 0.420
E14.5 With peripheral circulatory complications
0.000 0.582 0.417
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.588 0.412
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.591 0.409
E45 Retarded development following protein-energy malnutrition
0.000 0.591 0.409
E43 Unspecified severe protein-energy malnutrition
0.000 0.591 0.409
E42 Marasmic kwashiorkor
0.000 0.591 0.409
E41 Nutritional marasmus
0.000 0.591 0.409
E40 Kwashiorkor
0.000 0.591 0.409
E70.3 Albinism
0.000 0.595 0.405
E89.4 Postprocedural ovarian failure
0.000 0.595 0.405
E84.8 Cystic fibrosis with other manifestations
0.000 0.596 0.403
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.596 0.403
E16.1 Other hypoglycaemia
0.000 0.597 0.403
E74 Other disorders of carbohydrate metabolism
0.000 0.598 0.401
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.605 0.395
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.605 0.395
E70.2 Disorders of tyrosine metabolism
0.000 0.605 0.395
E70.1 Other hyperphenylalaninaemias
0.000 0.605 0.395
E70.0 Classical phenylketonuria
0.000 0.605 0.395
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.608 0.392
E32 Diseases of thymus
0.000 0.608 0.392
E31 Polyglandular dysfunction
0.000 0.608 0.392
E30 Disorders of puberty, not elsewhere classified
0.000 0.608 0.392
E14.2 Withrenal complications
0.000 0.608 0.392
E27.5 Adrenomedullary hyperfunction
0.000 0.609 0.391
E27.0 Other adrenocortical overactivity
0.000 0.609 0.391
E12.9 Without complications
0.000 0.611 0.389
E12.8 With unspecified complications
0.000 0.611 0.389
E12.7 With multiple complications
0.000 0.611 0.389
E12.6 With other specified complications
0.000 0.611 0.389
E12.5 With peripheral circulatory complications
0.000 0.611 0.389
E12.4 With neurological complications
0.000 0.611 0.389
E12.3 With ophthalmic complications
0.000 0.611 0.389
E12.2 With renal complications
0.000 0.611 0.389
E12.1 With ketoacidosis
0.000 0.611 0.389
E12.0 With coma
0.000 0.611 0.389
E65 Localised adiposity
0.000 0.612 0.388
E71.3 Disorders of fatty-acid metabolism
0.000 0.612 0.387
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.612 0.387
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.612 0.387
E71.0 Maple-syrup-urine disease
0.000 0.612 0.387
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.612 0.387
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.612 0.387
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.612 0.387
E76.2 Other mucopolysaccharidoses
0.000 0.612 0.387
E76.1 Mucopolysaccharidosis, type II
0.000 0.612 0.387
E76.0 Mucopolysaccharidosis, type I
0.000 0.612 0.387
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.612 0.387
E77.8 Other disorders of glycoprotein metabolism
0.000 0.612 0.387
E77.1 Defects in glycoprotein degradation
0.000 0.612 0.387
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.612 0.387
E78.4 Other hyperlipidaemia
0.000 0.615 0.385
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.616 0.384
E14.7 With multiple complications
0.000 0.619 0.381
E14.0 With coma
0.000 0.619 0.381
E89.0 Postprocedural hypothyroidism
0.000 0.620 0.380
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.621 0.379
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.622 0.378
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.622 0.378
E72.5 Disorders of glycine metabolism
0.000 0.622 0.378
E72.4 Disorders of ornithine metabolism
0.000 0.622 0.378
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.622 0.378
E72.2 Disorders of urea cycle metabolism
0.000 0.622 0.378
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.622 0.378
E75.6 Lipid storage disorder, unspecified
0.000 0.622 0.378
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.622 0.378
E75.3 Sphingolipidosis, unspecified
0.000 0.622 0.378
E75.1 Other gangliosidosis
0.000 0.622 0.378
E75.0 GM2 gangliosidosis
0.000 0.622 0.378
E75.5 Other lipid storage disorders
0.000 0.623 0.377
E29 Testicular dysfunction
0.000 0.623 0.377
E26 Hyperaldosteronism
0.000 0.624 0.376
E24 Cushing's syndrome
0.000 0.625 0.375
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.625 0.374
E78.6 Lipoprotein deficiency
0.000 0.630 0.370
E75.2 Other sphingolipidosis
0.000 0.634 0.366
E72.0 Disorders of amino-acid transport
0.000 0.634 0.366
E85 Amyloidosis
0.000 0.634 0.365
E14.6 With other specified complications
0.000 0.635 0.365
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.640 0.360
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.640 0.360
E14.1 With ketoacidosis
0.000 0.640 0.359
E14.4 With neurological complications
0.000 0.644 0.356
E20.9 Hypoparathyroidism, unspecified
0.000 0.648 0.352
E83.4 Disorders of magnesium metabolism
0.000 0.650 0.350
E83.5 Disorders of calcium metabolism
0.000 0.653 0.347
E05.9 Thyrotoxicosis, unspecified
0.000 0.655 0.345
E73.8 Other lactose intolerance
0.000 0.658 0.342
E73.1 Secondary lactase deficiency
0.000 0.658 0.342
E73.0 Congenital lactase deficiency
0.000 0.658 0.342
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.659 0.341
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.659 0.341
E89.1 Postprocedural hypoinsulinaemia
0.000 0.659 0.341
E27.2 Addisonian crisis
0.000 0.667 0.333
E06 Thyroiditis
0.000 0.667 0.333
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.671 0.329
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.671 0.329
E79.1 Lesch-Nyhan syndrome
0.000 0.671 0.329
E67 Other hyperalimentation
0.000 0.671 0.329
E68 Sequelae of hyperalimentation
0.000 0.671 0.329
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.676 0.324
E00 Congenital iodine-deficiency syndrome
0.000 0.676 0.324
E78.3 Hyperchylomicronaemia
0.000 0.676 0.324
E25.9 Adrenogenital disorder, unspecified
0.000 0.686 0.314
E25.8 Other adrenogenital disorders
0.000 0.686 0.314
E20.8 Other hypoparathyroidism
0.000 0.689 0.311
E20.1 Pseudohypoparathyroidism
0.000 0.689 0.311
E20.0 Idiopathic hypoparathyroidism
0.000 0.689 0.311
E05.8 Other thyrotoxicosis
0.000 0.692 0.308
E24.2 Drug-induced Cushing's syndrome
0.000 0.698 0.302
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.701 0.299
E05.5 Thyroid crisis or storm
0.000 0.705 0.295
E05.4 Thyrotoxicosis factitia
0.000 0.705 0.295
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.705 0.295
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.706 0.294
E44.1 Mild protein-energy malnutrition
0.000 0.706 0.293
E44.0 Moderate protein-energy malnutrition
0.000 0.706 0.293
E14.8 With unspecified complications
0.000 0.707 0.293
E34 Other endocrine disorders
0.000 0.708 0.292
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.712 0.288
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.712 0.288
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.712 0.288
E74.2 Disorders of galactose metabolism
0.000 0.712 0.288
E74.1 Disorders of fructose metabolism
0.000 0.712 0.288
E24.8 Other Cushing's syndrome
0.000 0.718 0.282
E30.9 Disorder of puberty, unspecified
0.000 0.719 0.281
E30.8 Other disorders of puberty
0.000 0.719 0.281
E30.1 Precocious puberty
0.000 0.719 0.281
E30.0 Delayed puberty
0.000 0.719 0.281
E31.9 Polyglandular dysfunction, unspecified
0.000 0.719 0.281
E31.8 Other polyglandular dysfunction
0.000 0.719 0.281
E31.1 Polyglandular hyperfunction
0.000 0.719 0.281
E31.0 Autoimmune polyglandular failure
0.000 0.719 0.281
E32.9 Disease of thymus, unspecified
0.000 0.719 0.281
E32.8 Other diseases of thymus
0.000 0.719 0.281
E32.1 Abscess of thymus
0.000 0.719 0.281
E32.0 Persistent hyperplasia of thymus
0.000 0.719 0.281
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.719 0.281
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.719 0.281
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.719 0.281
E85.8 Other amyloidosis
0.000 0.719 0.281
E03 Other hypothyroidism
0.000 0.720 0.280
E73.9 Lactose intolerance, unspecified
0.000 0.721 0.278
E26.0 Primary hyperaldosteronism
0.000 0.721 0.278
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.721 0.278
E07 Other disorders of thyroid
0.000 0.722 0.278
E89.5 Postprocedural testicular hypofunction
0.000 0.722 0.277
K90 Intestinal malabsorption
0.000 0.725 0.275
E78.8 Other disorders of lipoprotein metabolism
0.000 0.728 0.271
E29.9 Testicular dysfunction, unspecified
0.000 0.730 0.270
E29.8 Other testicular dysfunction
0.000 0.730 0.270
E29.0 Testicular hyperfunction
0.000 0.730 0.270
E78.2 Mixed hyperlipidaemia
0.000 0.730 0.270
E26.8 Other hyperaldosteronism
0.000 0.730 0.270
E26.1 Secondary hyperaldosteronism
0.000 0.730 0.270
E23 Hypofunction and other disorders of pituitary gland
0.000 0.731 0.269
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.731 0.269
E24.3 Ectopic ACTH syndrome
0.000 0.731 0.269
E24.1 Nelson's syndrome
0.000 0.731 0.269
E24.0 Pituitary-dependent Cushing's disease
0.000 0.732 0.268
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.738 0.262
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.738 0.262
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.738 0.262
E78.1 Pure hyperglyceridaemia
0.000 0.741 0.259
E29.1 Testicular hypofunction
0.000 0.745 0.255
E03.8 Other specified hypothyroidism
0.000 0.749 0.251
E06.3 Autoimmune thyroiditis
0.000 0.751 0.249
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.752 0.247
E06.1 Subacute thyroiditis
0.000 0.752 0.247
E26.9 Hyperaldosteronism, unspecified
0.000 0.756 0.243
E06.5 Other chronic thyroiditis
0.000 0.757 0.243
E28 Ovarian dysfunction
0.000 0.759 0.240
E74.0 Glycogen storage disease
0.001 0.760 0.240
E06.4 Drug-induced thyroiditis
0.000 0.761 0.238
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.761 0.238
E06.0 Acute thyroiditis
0.000 0.761 0.238
E67.8 Other specified hyperalimentation
0.000 0.764 0.236
E67.3 Hypervitaminosis D
0.000 0.764 0.236
E67.2 Megavitamin-B6 syndrome
0.000 0.764 0.236
E67.1 Hypercarotenaemia
0.000 0.764 0.236
E67.0 Hypervitaminosis A
0.000 0.764 0.236
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.767 0.233
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.767 0.233
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.767 0.233
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.767 0.233
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.767 0.233
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.767 0.233
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.767 0.233
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.767 0.233
E89.2 Postprocedural hypoparathyroidism
0.000 0.767 0.232
E85.9 Amyloidosis, unspecified
0.000 0.768 0.231
E85.3 Secondary systemic amyloidosis
0.000 0.776 0.224
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.776 0.224
E06.9 Thyroiditis, unspecified
0.000 0.780 0.220
E27.9 Disorder of adrenal gland, unspecified
0.001 0.784 0.216
E23.2 Diabetes insipidus
0.000 0.787 0.213
E34.9 Endocrine disorder, unspecified
0.000 0.788 0.211
E34.5 Androgen resistance syndrome
0.000 0.790 0.209
E34.4 Constitutional tall stature
0.000 0.790 0.209
E34.3 Short stature, not elsewhere classified
0.000 0.790 0.209
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.790 0.209
E34.1 Other hypersecretion of intestinal hormones
0.000 0.790 0.209
K90.8 Other intestinal malabsorption
0.000 0.792 0.208
E89.3 Postprocedural hypopituitarism
0.000 0.794 0.205
E11 Non-insulin-dependent diabetes mellitus
0.000 0.798 0.202
E03.5 Myxoedema coma
0.000 0.799 0.201
E03.4 Atrophy of thyroid (acquired)
0.000 0.799 0.201
E03.3 Postinfectious hypothyroidism
0.000 0.799 0.201
E07.9 Disorder of thyroid, unspecified
0.000 0.799 0.201
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.800 0.200
E27.8 Other specified disorders of adrenal gland
0.001 0.800 0.199
E07.1 Dyshormogenetic goitre
0.000 0.801 0.199
E07.0 Hypersecretion of calcitonin
0.000 0.801 0.199
K90.3 Pancreatic steatorrhoea
0.000 0.803 0.197
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.803 0.197
K90.1 Tropical sprue
0.000 0.803 0.197
E03.1 Congenital hypothyroidism without goitre
0.000 0.803 0.196
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.807 0.193
E23.1 Drug-induced hypopituitarism
0.000 0.807 0.193
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.810 0.190
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.812 0.188
E23.7 Disorder of pituitary gland, unspecified
0.000 0.815 0.185
E23.6 Other disorders of pituitary gland
0.000 0.824 0.176
E34.8 Other specified endocrine disorders
0.000 0.824 0.175
E85.4 Organ-limited amyloidosis
0.001 0.826 0.173
E28.9 Ovarian dysfunction, unspecified
0.000 0.827 0.172
E28.8 Other ovarian dysfunction
0.000 0.827 0.172
E28.1 Androgen excess
0.000 0.827 0.172
E28.0 Oestrogen excess
0.000 0.827 0.172
E11.2 With renal complications
0.000 0.827 0.173
E24.9 Cushing's syndrome, unspecified
0.000 0.829 0.171
E34.0 Carcinoid syndrome
0.000 0.840 0.160
E11.1 With ketoacidosis
0.000 0.842 0.158
E11.6 With other specified complications
0.000 0.842 0.157
E50-E64 Other nutritional deficiencies
0.000 0.846 0.153
E07.8 Other specified disorders of thyroid
0.000 0.850 0.150
E11.8 With unspecified complications
0.000 0.851 0.149
E11.7 With multiple complications
0.000 0.855 0.145
E22 Hyperfunction of pituitary gland
0.000 0.855 0.144
E14.9 Without complications
0.000 0.863 0.137
E04 Other non-toxic goitre
0.000 0.864 0.136
E28.2 Polycystic ovarian syndrome
0.000 0.871 0.129
E11.0 With coma
0.000 0.875 0.125
E11.4 With neurological complications
0.000 0.880 0.120
E04.0 Non-toxic diffuse goitre
0.000 0.887 0.112
K90.9 Intestinal malabsorption, unspecified
0.000 0.888 0.112
E11.5 With peripheral circulatory complications
0.000 0.889 0.111
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.890 0.110
E63 Other nutritional deficiencies
0.000 0.890 0.110
E50 Vitamin A deficiency
0.000 0.890 0.110
E60 Dietary zinc deficiency
0.000 0.890 0.110
E59 Dietary selenium deficiency
0.000 0.890 0.110
E52 Niacin deficiency [pellagra]
0.000 0.890 0.110
E28.3 Primary ovarian failure
0.001 0.893 0.106
E51 Thiamine deficiency
0.000 0.894 0.106
E58 Dietary calcium deficiency
0.000 0.894 0.105
E56 Other vitamin deficiencies
0.000 0.895 0.105
E22.8 Other hyperfunction of pituitary gland
0.000 0.896 0.104
E04.8 Other specified non-toxic goitre
0.000 0.902 0.098
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.907 0.093
E53 Deficiency of other B group vitamins
0.000 0.908 0.092
E54 Ascorbic acid deficiency
0.000 0.911 0.088
E04.9 Non-toxic goitre, unspecified
0.000 0.913 0.087
E55 Vitamin D deficiency
0.000 0.920 0.080
E50.9 Vitamin A deficiency, unspecified
0.000 0.921 0.079
E50.8 Other manifestations of vitamin A deficiency
0.000 0.921 0.079
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.921 0.079
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.921 0.079
E50.5 Vitamin A deficiency with night blindness
0.000 0.921 0.079
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.921 0.079
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.921 0.079
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.921 0.079
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.921 0.079
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.921 0.079
E63.9 Nutritional deficiency, unspecified
0.000 0.921 0.079
E63.8 Other specified nutritional deficiencies
0.000 0.921 0.079
E63.1 Imbalance of constituents of food intake
0.000 0.921 0.079
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.921 0.079
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.921 0.079
E64.8 Sequelae of other nutritional deficiencies
0.000 0.921 0.079
E64.3 Sequelae of rickets
0.000 0.921 0.079
E64.2 Sequelae of vitamin C deficiency
0.000 0.921 0.079
E64.1 Sequelae of vitamin A deficiency
0.000 0.921 0.079
E64.0 Sequelae of protein-energy malnutrition
0.000 0.921 0.079
E51.9 Thiamine deficiency, unspecified
0.000 0.924 0.076
E51.8 Other manifestations of thiamine deficiency
0.000 0.924 0.076
E51.1 Beriberi
0.000 0.924 0.076
E22.1 Hyperprolactinaemia
0.000 0.924 0.076
E56.9 Vitamin deficiency, unspecified
0.000 0.924 0.075
E56.8 Deficiency of other vitamins
0.000 0.924 0.075
E56.0 Deficiency of vitamin E
0.000 0.924 0.075
E66 Obesity
0.000 0.927 0.073
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.927 0.073
E53.9 Vitamin B deficiency, unspecified
0.000 0.927 0.073
E51.2 Wernicke's encephalopathy
0.000 0.928 0.072
E23.0 Hypopituitarism
0.000 0.928 0.072
E56.1 Deficiency of vitamin K
0.000 0.930 0.070
E22.0 Acromegaly and pituitary gigantism
0.000 0.933 0.066
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.933 0.066
E53.1 Pyridoxine deficiency
0.000 0.934 0.066
E53.0 Riboflavin deficiency
0.000 0.934 0.066
E86 Volume depletion
0.000 0.934 0.066
E61 Deficiency of other nutrient elements
0.000 0.935 0.065
E55.0 Rickets, active
0.000 0.942 0.057
E11.3 With ophthalmic complications
0.000 0.942 0.058
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.945 0.054
E66.1 Drug-induced obesity
0.000 0.947 0.053
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.951 0.048
E61.9 Deficiency of nutrient element, unspecified
0.000 0.953 0.047
E61.8 Deficiency of other specified nutrient elements
0.000 0.953 0.047
E61.7 Deficiency of multiple nutrient elements
0.000 0.953 0.047
E61.6 Vanadium deficiency
0.000 0.953 0.047
E61.5 Molybdenum deficiency
0.000 0.953 0.047
E61.4 Chromium deficiency
0.000 0.953 0.047
E61.3 Manganese deficiency
0.000 0.953 0.047
E61.0 Copper deficiency
0.000 0.953 0.047
E04.2 Non-toxic multinodular goitre
0.000 0.954 0.046
E21.4 Other specified disorders of parathyroid gland
0.000 0.954 0.046
E21.2 Other hyperparathyroidism
0.000 0.955 0.045
E66.0 Obesity due to excess calories
0.000 0.958 0.042
E61.2 Magnesium deficiency
0.000 0.959 0.041
K51.2 Ulcerative (chronic) proctitis
0.035 0.965 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.967 0.033
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.969 0.031
E55.9 Vitamin D deficiency, unspecified
0.000 0.973 0.027
E11.9 Without complications
0.000 0.981 0.019
E61.1 Iron deficiency
0.001 0.982 0.017
E04.1 Non-toxic single thyroid nodule
0.000 0.983 0.016
K90-K93 Other diseases of the digestive system
0.000 0.984 0.016
G35 Multiple sclerosis
0.000 0.984 0.016
E78.5 Hyperlipidaemia, unspecified
0.000 0.984 0.016
E21.3 Hyperparathyroidism, unspecified
0.000 0.984 0.015
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.987 0.013
E66.9 Obesity, unspecified
0.000 0.988 0.012
E21.0 Primary hyperparathyroidism
0.000 0.988 0.012
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.988 0.012
G30.9 Alzheimer's disease, unspecified
0.000 0.988 0.012
R31 Unspecified haematuria
0.011 0.989 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.011 0.989 0.000
H11 Other disorders of conjunctiva
0.011 0.989 0.000
H11.9 Disorder of conjunctiva, unspecified
0.011 0.989 0.000
H11.8 Other specified disorders of conjunctiva
0.010 0.990 0.000
E87.7 Fluid overload
0.000 0.990 0.010
H11.0 Pterygium
0.010 0.990 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.991 0.009
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.009 0.991 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.991 0.009
K93.1 Megacolon in Chagas' disease
0.000 0.991 0.009
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.991 0.009
N04.9 Unspecified
0.000 0.991 0.009
G30 Alzheimer's disease
0.000 0.991 0.009
H11.1 Conjunctival degenerations and deposits
0.008 0.992 0.000
E87.5 Hyperkalaemia
0.000 0.992 0.008
E87.0 Hyperosmolality and hypernatraemia
0.000 0.992 0.007
H11.2 Conjunctival scars
0.007 0.993 0.000
G30.0 Alzheimer's disease with early onset
0.000 0.993 0.007
E03.9 Hypothyroidism, unspecified
0.000 0.993 0.007
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.993 0.007
G30.1 Alzheimer's disease with late onset
0.000 0.993 0.007
O04.9 Complete or unspecified, without complication
0.006 0.994 0.000
M41.9 Scoliosis, unspecified
0.006 0.994 0.000
G30.8 Other Alzheimer's disease
0.000 0.994 0.006
M41.96 Scoliosis, unspecified (Lumbar region)
0.006 0.994 0.000
G30-G32 Other degenerative diseases of the nervous system
0.000 0.994 0.006
E87.3 Alkalosis
0.000 0.994 0.006
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.006 0.994 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.994 0.006
G31.8 Other specified degenerative diseases of nervous system
0.000 0.994 0.006
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.006 0.994 0.000
G31.0 Circumscribed brain atrophy
0.000 0.995 0.005
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.995 0.005
M41.99 Scoliosis, unspecified (Site unspecified)
0.005 0.995 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.005 0.995 0.000
N04 Nephrotic syndrome
0.000 0.995 0.005
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.005 0.995 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.005 0.995 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.005 0.995 0.000
D73.8 Other diseases of spleen
0.000 0.995 0.005
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.005 0.995 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.995 0.005
M41.92 Scoliosis, unspecified (Cervical region)
0.004 0.995 0.000
C71.2 Temporal lobe
0.004 0.996 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.996 0.004
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.996 0.004
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.004 0.996 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.996 0.004
D73 Diseases of spleen
0.000 0.996 0.004
D73.5 Infarction of spleen
0.000 0.996 0.004
H10-H13 Disorders of conjunctiva
0.004 0.996 0.000
E66.8 Other obesity
0.000 0.996 0.004
N04.0 Minor glomerular abnormality
0.000 0.996 0.004
N04.8 Other
0.000 0.996 0.004
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.996 0.004
N04.6 Dense deposit disease
0.000 0.996 0.004
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.996 0.004
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.996 0.004
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.996 0.004
N04.2 Diffuse membranous glomerulonephritis
0.000 0.996 0.004
N04.1 Focal and segmental glomerular lesions
0.000 0.996 0.004
Z88.1 Personal history of allergy to other antibiotic agents
0.004 0.996 0.000
M25.57 Pain in joint (Ankle and foot)
0.000 0.996 0.004
G37 Other demyelinating diseases of central nervous system
0.000 0.996 0.004
V23.4 Driver injured in traffic accident
0.000 0.996 0.004
H11.3 Conjunctival haemorrhage
0.003 0.996 0.000
G36 Other acute disseminated demyelination
0.000 0.996 0.003
D73.0 Hyposplenism
0.000 0.996 0.004
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.996 0.004
D73.9 Disease of spleen, unspecified
0.000 0.996 0.003
Z74.0 Reduced mobility
0.000 0.996 0.004
M41 Scoliosis
0.004 0.996 0.000
D73.3 Abscess of spleen
0.000 0.997 0.003
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.997 0.003
Q65.8 Other congenital deformities of hip
0.003 0.997 0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.997 0.003
D73.2 Chronic congestive splenomegaly
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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