TreeWAS – Variant ID: rs10130556

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G93 Other disorders of brain	0.475	0.525	0.000
G93.6 Cerebral oedema	0.468	0.532	0.000
G93.8 Other specified disorders of brain	0.467	0.533	0.000
G93.2 Benign intracranial hypertension	0.456	0.544	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.454	0.546	0.000
G93.9 Disorder of brain, unspecified	0.415	0.585	0.000
G93.7 Reye's syndrome	0.340	0.659	0.000
G93.3 Postviral fatigue syndrome	0.329	0.671	0.000
G93.5 Compression of brain	0.323	0.677	0.000
G93.4 Encephalopathy, unspecified	0.270	0.730	0.000
G93.0 Cerebral cysts	0.197	0.803	0.000
G90-G99 Other disorders of the nervous system	0.039	0.961	0.000
I67.2 Cerebral atherosclerosis	0.031	0.969	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.030	0.970	0.000
G91 Hydrocephalus	0.029	0.971	0.000
I67.1 Cerebral aneurysm, nonruptured	0.029	0.971	0.000
G92 Toxic encephalopathy	0.028	0.971	0.000
I67 Other cerebrovascular diseases	0.028	0.972	0.000
G96 Other disorders of central nervous system	0.028	0.972	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.027	0.973	0.000
G91.9 Hydrocephalus, unspecified	0.027	0.973	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.026	0.974	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.026	0.974	0.000
I67.9 Cerebrovascular disease, unspecified	0.025	0.975	0.000
G25.3 Myoclonus	0.023	0.977	0.000
G96.0 Cerebrospinal fluid leak	0.023	0.977	0.000
G20-G26 Extrapyramidal and movement disorders	0.023	0.977	0.000
G91.0 Communicating hydrocephalus	0.023	0.977	0.000
D32.0 Cerebral meninges	0.023	0.977	0.000
G91.2 Normal-pressure hydrocephalus	0.023	0.977	0.000
I67.4 Hypertensive encephalopathy	0.022	0.978	0.000
G25 Other extrapyramidal and movement disorders	0.022	0.978	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.022	0.978	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.022	0.978	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.022	0.978	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.022	0.978	0.000
G30.9 Alzheimer's disease, unspecified	0.022	0.978	0.000
G20 Parkinson's disease	0.022	0.978	0.000
Chapter VI Diseases of the nervous system	0.021	0.979	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.021	0.979	0.000
D32.9 Meninges, unspecified	0.021	0.979	0.000
G30 Alzheimer's disease	0.020	0.979	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.020	0.980	0.000
I67.5 Moyamoya disease	0.020	0.980	0.000
I67.3 Progressive vascular leukoencephalopathy	0.020	0.980	0.000
G70-G73 Diseases of myoneural junction and muscle	0.020	0.980	0.000
G96.9 Disorder of central nervous system, unspecified	0.020	0.980	0.000
G30-G32 Other degenerative diseases of the nervous system	0.020	0.980	0.000
G70 Myasthenia gravis and other myoneural disorders	0.020	0.980	0.000
D32 Benign neoplasm of meninges	0.019	0.980	0.000
G96.8 Other specified disorders of central nervous system	0.019	0.981	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.019	0.981	0.000
G70.0 Myasthenia gravis	0.019	0.981	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.018	0.981	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.018	0.981	0.000
G25.0 Essential tremor	0.019	0.981	0.000
G24 Dystonia	0.019	0.981	0.000
G25.2 Other specified forms of tremor	0.018	0.982	0.000
G94.1 Hydrocephalus in neoplastic disease	0.018	0.982	0.000
G12 Spinal muscular atrophy and related syndromes	0.018	0.982	0.000
G24.9 Dystonia, unspecified	0.018	0.982	0.000
G91.8 Other hydrocephalus	0.017	0.982	0.000
G12.2 Motor neuron disease	0.017	0.983	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.017	0.983	0.000
G22 Parkinsonism in diseases classified elsewhere	0.017	0.983	0.000
G23 Other degenerative diseases of basal ganglia	0.016	0.983	0.000
G21 Secondary Parkinsonism	0.016	0.983	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.016	0.984	0.000
G25.4 Drug-induced chorea	0.016	0.984	0.000
G70.9 Myoneural disorder, unspecified	0.016	0.984	0.000
G30.1 Alzheimer's disease with late onset	0.016	0.984	0.000
G30.0 Alzheimer's disease with early onset	0.016	0.984	0.000
G72 Other myopathies	0.015	0.985	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.015	0.985	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.015	0.985	0.000
G25.1 Drug-induced tremor	0.015	0.985	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.015	0.985	0.000
G25.5 Other chorea	0.015	0.985	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.015	0.985	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.014	0.985	0.000
G71 Primary disorders of muscles	0.014	0.986	0.000
G70.8 Other specified myoneural disorders	0.014	0.986	0.000
G70.2 Congenital and developmental myasthenia	0.014	0.986	0.000
G70.1 Toxic myoneural disorders	0.014	0.986	0.000
I67.8 Other specified cerebrovascular diseases	0.014	0.986	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.014	0.986	0.000
E23.0 Hypopituitarism	0.014	0.986	0.000
G24.4 Idiopathic orofacial dystonia	0.013	0.986	0.000
G24.2 Idiopathic nonfamilial dystonia	0.013	0.986	0.000
G24.1 Idiopathic familial dystonia	0.013	0.986	0.000
G24.0 Drug-induced dystonia	0.013	0.986	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.013	0.986	0.000
G11 Hereditary ataxia	0.013	0.987	0.000
G72.9 Myopathy, unspecified	0.013	0.987	0.000
G14 Postpolio syndrome	0.013	0.987	0.000
G10 Huntington's disease	0.013	0.987	0.000
G12.9 Spinal muscular atrophy, unspecified	0.013	0.987	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.013	0.987	0.000
G12.1 Other inherited spinal muscular atrophy	0.013	0.987	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.013	0.987	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.013	0.987	0.000
G21.9 Secondary Parkinsonism, unspecified	0.013	0.987	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.012	0.987	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.012	0.988	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.012	0.988	0.000
G21.8 Other secondary Parkinsonism	0.012	0.988	0.000
G21.4 Vascular parkinsonism	0.012	0.988	0.000
G21.3 Postencephalitic Parkinsonism	0.012	0.988	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.012	0.988	0.000
G21.0 Malignant neuroleptic syndrome	0.012	0.988	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.012	0.988	0.000
G23.3 Multiple system atrophy, cerebellar type	0.012	0.988	0.000
G23.2 Striatonigral degeneration	0.012	0.988	0.000
G23.0 Hallervorden-Spatz disease	0.012	0.988	0.000
G30.8 Other Alzheimer's disease	0.012	0.988	0.000
G24.5 Blepharospasm	0.012	0.988	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.012	0.988	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.012	0.988	0.000
G24.3 Spasmodic torticollis	0.012	0.988	0.000
G24.8 Other dystonia	0.011	0.988	0.000
G11.4 Hereditary spastic paraplegia	0.011	0.988	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.011	0.988	0.000
G72.8 Other specified myopathies	0.011	0.989	0.000
G60 Hereditary and idiopathic neuropathy	0.011	0.989	0.000
G72.3 Periodic paralysis	0.011	0.989	0.000
G72.2 Myopathy due to other toxic agents	0.011	0.989	0.000
D32.1 Spinal meninges	0.011	0.989	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.011	0.989	0.000
G90 Disorders of autonomic nervous system	0.011	0.989	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.011	0.989	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.011	0.989	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.011	0.989	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.011	0.989	0.000
G71.1 Myotonic disorders	0.011	0.989	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.011	0.989	0.000
G73.7 Myopathy other diseases classified elsewhere	0.011	0.989	0.000
G73.6 Myopathy in metabolic diseases	0.011	0.989	0.000
G73.5 Myopathy in endocrine diseases	0.011	0.989	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.011	0.989	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.011	0.989	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.011	0.989	0.000
G73.1 Eaton-Lambert syndrome	0.011	0.989	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.011	0.989	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.010	0.989	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.010	0.989	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.010	0.989	0.000
G71.9 Primary disorder of muscle, unspecified	0.010	0.989	0.000
G71.8 Other primary disorders of muscles	0.010	0.989	0.000
G71.2 Congenital myopathies	0.010	0.989	0.000
G64 Other disorders of peripheral nervous system	0.010	0.989	0.000
G72.1 Alcoholic myopathy	0.010	0.990	0.000
U80.1 Methicillin resistant agent	0.010	0.990	0.000
G72.0 Drug-induced myopathy	0.010	0.990	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.990	0.010
G61 Inflammatory polyneuropathy	0.010	0.990	0.000
G95 Other diseases of spinal cord	0.010	0.990	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.010	0.990	0.000
G11.8 Other hereditary ataxias	0.010	0.990	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.010	0.990	0.000
G11.2 Late-onset cerebellar ataxia	0.010	0.990	0.000
G11.0 Congenital nonprogressive ataxia	0.010	0.990	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.010	0.990	0.000
G97.8 Other postprocedural disorders of nervous system	0.009	0.990	0.000
G11.1 Early-onset cerebellar ataxia	0.009	0.991	0.000
G36 Other acute disseminated demyelination	0.009	0.991	0.000
G62 Other polyneuropathies	0.009	0.991	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.009	0.991	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.009	0.991	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.009	0.991	0.000
G90.8 Other disorders of autonomic nervous system	0.008	0.991	0.000
G60.3 Idiopathic progressive neuropathy	0.008	0.992	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.008	0.992	0.000
G60.1 Refsum's disease	0.008	0.992	0.000
I44.2 Atrioventricular block, complete	0.000	0.992	0.008
G36.0 Neuromyelitis optica [Devic]	0.008	0.992	0.000
G90.4 Autonomic dysreflexia	0.008	0.992	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.008	0.992	0.000
G61.0 Guillain-Barre syndrome	0.008	0.992	0.000
H65.3 Chronic mucoid otitis media	0.008	0.992	0.000
G95.1 Vascular myelopathies	0.008	0.992	0.000
K01.1 Impacted teeth	0.008	0.992	0.000
G71.0 Muscular dystrophy	0.008	0.992	0.000
G62.0 Drug-induced polyneuropathy	0.008	0.992	0.000
G91.1 Obstructive hydrocephalus	0.006	0.992	0.002
G61.1 Serum neuropathy	0.007	0.992	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.007	0.992	0.000
G95.0 Syringomyelia and syringobulbia	0.007	0.993	0.000
S83.2 Tear of meniscus, current	0.007	0.993	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.007	0.993	0.000
G60.0 Hereditary motor and sensory neuropathy	0.007	0.993	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.007	0.993	0.000
G37 Other demyelinating diseases of central nervous system	0.007	0.993	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.007	0.993	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.993	0.007
G62.1 Alcoholic polyneuropathy	0.007	0.993	0.000
U80 Agent resistant to penicillin and related antibiotics	0.007	0.993	0.000
G36.9 Acute disseminated demyelination, unspecified	0.007	0.993	0.000
G36.8 Other specified acute disseminated demyelination	0.007	0.993	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.007	0.993	0.000
G62.2 Polyneuropathy due to other toxic agents	0.007	0.993	0.000
U80.0 Penicillin resistant agent	0.007	0.993	0.000
G62.8 Other specified polyneuropathies	0.007	0.993	0.000
N60.3 Fibrosclerosis of breast	0.000	0.993	0.007
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.006	0.994	0.000
G90.3 Multisystem degeneration	0.006	0.994	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.006	0.994	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.006	0.994	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.006	0.994	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.006	0.994	0.000
G11.9 Hereditary ataxia, unspecified	0.006	0.994	0.000
H74 Other disorders of middle ear and mastoid	0.006	0.994	0.000
H73 Other disorders of tympanic membrane	0.006	0.994	0.000
S82.00 Fracture of patella (closed)	0.006	0.994	0.000
H74.1 Adhesive middle ear disease	0.006	0.994	0.000
H65-H75 Diseases of middle ear and mastoid	0.006	0.994	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.006	0.994	0.000
E23 Hypofunction and other disorders of pituitary gland	0.006	0.994	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.006	0.994	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
G95.9 Disease of spinal cord, unspecified	0.006	0.994	0.000
H65 Nonsuppurative otitis media	0.006	0.994	0.000
X49.9 Unspecified place	0.006	0.994	0.000
G31.0 Circumscribed brain atrophy	0.006	0.994	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.006	0.994	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.005	0.994	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.005	0.995	0.000
G37.5 Concentric sclerosis [Balo]	0.005	0.995	0.000
G37.4 Subacute necrotising myelitis	0.005	0.995	0.000
G37.2 Central pontine myelinolysis	0.005	0.995	0.000
G37.1 Central demyelination of corpus callosum	0.005	0.995	0.000
G37.0 Diffuse sclerosis	0.005	0.995	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.005	0.995	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.005	0.995	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.005	0.995	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.005	0.995	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.005	0.995	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.005	0.995	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.005	0.995	0.000
G63.1 Polyneuropathy in neoplastic disease	0.005	0.995	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
H72 Perforation of tympanic membrane	0.005	0.995	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.005	0.995	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.005	0.995	0.000
H71 Cholesteatoma of middle ear	0.005	0.995	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.005	0.995	0.000
G90.2 Horner's syndrome	0.005	0.995	0.000
H73.8 Other specified disorders of tympanic membrane	0.005	0.995	0.000
S83.1 Dislocation of knee	0.005	0.995	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.005	0.995	0.000
S83.7 Injury to multiple structures of knee	0.005	0.995	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.005	0.995	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.004	0.995	0.001
S82.01 Fracture of patella (open)	0.005	0.995	0.000
H73.0 Acute myringitis	0.005	0.995	0.000
H74.4 Polyp of middle ear	0.005	0.995	0.000
H68 Eustachian salpingitis and obstruction	0.005	0.995	0.000
S82.0 Fracture of patella	0.005	0.995	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.005	0.995	0.000
S83.0 Dislocation of patella	0.005	0.995	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.004	0.995	0.000
M72.2 Plantar fascial fibromatosis	0.000	0.995	0.005
H70 Mastoiditis and related conditions	0.005	0.995	0.000
H69 Other disorders of Eustachian tube	0.005	0.995	0.000
H72.2 Other marginal perforations of tympanic membrane	0.005	0.995	0.000
G00 Bacterial meningitis, not elsewhere classified	0.004	0.995	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.004	0.995	0.000
H65.0 Acute serous otitis media	0.004	0.995	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.995	0.000
H67 Otitis media in diseases classified elsewhere	0.004	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.004	0.995	0.000
S83.3 Tear of articular cartilage of knee, current	0.004	0.995	0.000
N60.8 Other benign mammary dysplasias	0.000	0.995	0.004
G03 Meningitis due to other and unspecified causes	0.004	0.995	0.000
N60 Benign mammary dysplasia	0.000	0.996	0.004
G31.2 Degeneration of nervous system due to alcohol	0.004	0.996	0.000
H65.1 Other acute nonsuppurative otitis media	0.004	0.996	0.000
H72.8 Other perforations of tympanic membrane	0.004	0.996	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.004	0.996	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
G02.1 Meningitis in mycoses	0.004	0.996	0.000
G62.9 Polyneuropathy, unspecified	0.004	0.996	0.000
H72.1 Attic perforation of tympanic membrane	0.004	0.996	0.000
N60.1 Diffuse cystic mastopathy	0.000	0.996	0.004
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.004	0.996	0.000
H73.1 Chronic myringitis	0.004	0.996	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.004	0.996	0.000
G06.0 Intracranial abscess and granuloma	0.004	0.996	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.004	0.996	0.000
G95.8 Other specified diseases of spinal cord	0.004	0.996	0.000
E22.0 Acromegaly and pituitary gigantism	0.004	0.996	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.004	0.996	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.004	0.996	0.000
H70.0 Acute mastoiditis	0.004	0.996	0.000
E23.2 Diabetes insipidus	0.004	0.996	0.000
C71 Malignant neoplasm of brain	0.004	0.996	0.000
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.004	0.996	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.004	0.996	0.000
C71.1 Frontal lobe	0.004	0.996	0.000
G61.8 Other inflammatory polyneuropathies	0.004	0.996	0.001
H68.1 Obstruction of Eustachian tube	0.004	0.996	0.000
E23.7 Disorder of pituitary gland, unspecified	0.004	0.996	0.000
N60.9 Benign mammary dysplasia, unspecified	0.000	0.996	0.004
G00.8 Other bacterial meningitis	0.004	0.996	0.000
G06.2 Extradural and subdural abscess, unspecified	0.004	0.996	0.000
X49.6 Industrial and construction area	0.004	0.996	0.000
M23.5 Chronic instability of knee	0.004	0.996	0.000
S82.20 Fracture of shaft of tibia (closed)	0.004	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.004	0.996	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.004	0.996	0.000
H69.8 Other specified disorders of Eustachian tube	0.004	0.996	0.000
H70.1 Chronic mastoiditis	0.004	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.004	0.996	0.000
G31.8 Other specified degenerative diseases of nervous system	0.004	0.996	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.004	0.996	0.000
C71.4 Occipital lobe	0.004	0.996	0.000
E23.6 Other disorders of pituitary gland	0.004	0.996	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.996	0.004
C71.0 Cerebrum, except lobes and ventricles	0.004	0.996	0.000
H65.2 Chronic serous otitis media	0.004	0.996	0.000
H68.0 Eustachian salpingitis	0.004	0.996	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.003	0.996	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.003	0.996	0.000
G00.3 Staphylococcal meningitis	0.003	0.996	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.003	0.996	0.000
M72.28 Plantar fascial fibromatosis-Other	0.000	0.996	0.003
M72.26 Plantar fascial fibromatosis-Lower Leg	0.000	0.996	0.003
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.000	0.996	0.003
M72.24 Plantar fascial fibromatosis-Hand	0.000	0.996	0.003
M72.23 Plantar fascial fibromatosis-Forearm	0.000	0.996	0.003
M72.22 Plantar fascial fibromatosis-Upper arm	0.000	0.996	0.003
M72.21 Plantar fascial fibromatosis-Shldr region	0.000	0.996	0.003
M72.20 Plantar fascial fibromatosis-Mult sites	0.000	0.996	0.003
H70.2 Petrositis	0.003	0.996	0.000
H69.0 Patulous Eustachian tube	0.003	0.996	0.000
G00.0 Haemophilus meningitis	0.003	0.996	0.000
K01 Embedded and impacted teeth	0.004	0.996	0.000
G00.2 Streptococcal meningitis	0.003	0.996	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.003	0.996	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.003	0.996	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.003	0.996	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.996	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
S93.1 Dislocation of toe(s)	0.000	0.996	0.004
M72.29 Plantar fascial fibromatosis-Site unspec	0.000	0.996	0.003
G03.8 Meningitis due to other specified causes	0.003	0.996	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.003	0.996	0.000
G03.1 Chronic meningitis	0.003	0.996	0.000
G03.0 Nonpyogenic meningitis	0.003	0.996	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.003	0.996	0.000
C71.6 Cerebellum	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.997	0.003
C71.2 Temporal lobe	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.003	0.997	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.003	0.997	0.000
G81 Hemiplegia	0.003	0.997	0.000
X49.4 Street and highway	0.003	0.997	0.000
X49.0 Home	0.003	0.997	0.000
X49.8 Other specified place	0.003	0.997	0.000
X49.7 Farm	0.003	0.997	0.000
X49.5 Trade and service area	0.003	0.997	0.000
X49.3 Sports and athletics area	0.003	0.997	0.000
X49.2 School, other institution and public administrative area	0.003	0.997	0.000
X49.1 Residential institution	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
L85.9 Epidermal thickening, unspecified	0.000	0.997	0.003
C71.5 Cerebral ventricle	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.003	0.997	0.000
G95.2 Cord compression, unspecified	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
G82 Paraplegia and tetraplegia	0.003	0.997	0.000
G00.9 Bacterial meningitis, unspecified	0.003	0.997	0.000
G83 Other paralytic syndromes	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.997	0.003
M23.57 Chronic instability of knee (Capsular ligament)	0.003	0.997	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.003	0.997	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.003	0.997	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.003	0.997	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.003	0.997	0.000
G04.1 Tropical spastic paraplegia	0.003	0.997	0.000
G04.0 Acute disseminated encephalitis	0.003	0.997	0.000
G81.1 Spastic hemiplegia	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.997	0.003
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.003	0.997	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.003	0.997	0.000
N60.0 Solitary cyst of breast	0.000	0.997	0.003
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.003	0.997	0.000
C34.2 Middle lobe, bronchus or lung	0.000	0.997	0.003
C71.3 Parietal lobe	0.003	0.997	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.003	0.997	0.000
E34 Other endocrine disorders	0.003	0.997	0.000
K01.0 Embedded teeth	0.003	0.997	0.000
G06.1 Intraspinal abscess and granuloma	0.002	0.997	0.000
I45.3 Trifascicular block	0.000	0.997	0.003
E31 Polyglandular dysfunction	0.003	0.997	0.000
G83.3 Monoplegia, unspecified	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
G00.1 Pneumococcal meningitis	0.002	0.997	0.000
G81.0 Flaccid hemiplegia	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.003	0.997	0.000
X49.09 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Home; During unspecified activity	0.002	0.997	0.000
X49.48 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances; Street and highway;While engaged in other specified activities	0.002	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
U81 Agent resistant to vancomycin and related antibiotics	0.003	0.997	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.997	0.003
I45.2 Bifascicular block	0.000	0.997	0.003
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.002	0.997	0.000
G83.9 Paralytic syndrome, unspecified	0.003	0.997	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.997	0.003
G82.5 Tetraplegia, unspecified	0.003	0.997	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.003	0.997	0.000
G82.3 Flaccid tetraplegia	0.002	0.997	0.000
G82.0 Flaccid paraplegia	0.002	0.997	0.000
I45.5 Other specified heart block	0.000	0.997	0.003
G82.1 Spastic paraplegia	0.002	0.997	0.000
G83.5 Locked-in syndrome	0.002	0.997	0.000
G83.0 Diplegia of upper limbs	0.002	0.997	0.000
G03.9 Meningitis, unspecified	0.002	0.997	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.002	0.997	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.997	0.002
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.997	0.002
I45.4 Nonspecific intraventricular block	0.000	0.997	0.002
N60.4 Mammary duct ectasia	0.000	0.997	0.002
E26 Hyperaldosteronism	0.002	0.997	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.003	0.997	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.997	0.002
F06.7 Mild cognitive disorder	0.002	0.998	0.000
I45 Other conduction disorders	0.000	0.998	0.002
N60.2 Fibroadenosis of breast	0.000	0.998	0.002
U81.0 Vancomycin resistant agent	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
M19.94 Arthrosis, unspecified (Hand)	0.002	0.998	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.000	0.998	0.002
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.002
B35.1 Tinea unguium	0.000	0.998	0.002
G82.4 Spastic tetraplegia	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.002
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.002	0.998	0.000
U50 Level of care administered to neonates	0.002	0.998	0.000
U07 Emergency use of U07	0.002	0.998	0.000
U06 Emergency use of U06	0.002	0.998	0.000
U04 Severe acute respiratory syndrome [SARS]	0.002	0.998	0.000
U52 First in a series of a regular day/night admissions	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
I45.9 Conduction disorder, unspecified	0.000	0.998	0.002
X47.0 Home	0.002	0.998	0.000
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
D41.4 Bladder	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
G83.2 Monoplegia of upper limb	0.002	0.998	0.000
X47.9 Unspecified place	0.002	0.998	0.000
Y83.8 Other surgical procedures	0.000	0.998	0.002
G83.1 Monoplegia of lower limb	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.002
G83.8 Other specified paralytic syndromes	0.002	0.998	0.000
U81.8 Agent resistant to other vancomycin-related antibiotic	0.002	0.998	0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations