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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1015465
log Bayes Factor = 34.1173
Chromosome 6   position 30,086,340  (GRCh37) Explore rs1015465 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.003 0.997
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.003 0.997
E03 Other hypothyroidism
0.000 0.005 0.995
E00-E07 Disorders of thyroid gland
0.000 0.008 0.992
E10 Insulin-dependent diabetes mellitus
0.000 0.009 0.991
E10.9 Without complications
0.000 0.011 0.989
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.014 0.986
E10-E14 Diabetes mellitus
0.000 0.016 0.984
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.016 0.984
J33 Nasal polyp
0.000 0.025 0.975
J33.0 Polyp of nasal cavity
0.000 0.027 0.973
J47 Bronchiectasis
0.000 0.031 0.969
J40-J47 Chronic lower respiratory diseases
0.000 0.035 0.965
J33.9 Nasal polyp, unspecified
0.000 0.038 0.962
Chapter X Diseases of the respiratory system
0.000 0.039 0.961
J30-J39 Other diseases of upper respiratory tract
0.000 0.042 0.958
E10.3 With ophthalmic complications
0.000 0.044 0.956
E04 Other non-toxic goitre
0.000 0.058 0.942
J44 Other chronic obstructive pulmonary disease
0.000 0.058 0.942
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.068 0.932
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.071 0.929
E04.2 Non-toxic multinodular goitre
0.000 0.077 0.923
K51.9 Ulcerative colitis, unspecified
0.000 0.077 0.923
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.083 0.917
E10.1 With ketoacidosis
0.000 0.106 0.894
L40.8 Other psoriasis
0.886 0.114 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.116 0.884
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.119 0.881
E06 Thyroiditis
0.000 0.126 0.874
K51 Ulcerative colitis
0.000 0.126 0.874
L40.0 Psoriasis vulgaris
0.855 0.145 0.000
J33.8 Other polyp of sinus
0.000 0.147 0.853
E50-E64 Other nutritional deficiencies
0.000 0.173 0.827
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.176 0.824
J84 Other interstitial pulmonary diseases
0.000 0.177 0.823
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.179 0.821
E06.3 Autoimmune thyroiditis
0.000 0.192 0.808
J30 Vasomotor and allergic rhinitis
0.000 0.194 0.806
E10.2 With renal complications
0.000 0.196 0.804
J90-J94 Other diseases of pleura
0.000 0.200 0.800
E10.4 With neurological complications
0.000 0.201 0.799
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.222 0.778
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.223 0.777
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.225 0.775
K51.4 Pseudopolyposis of colon
0.000 0.233 0.767
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.236 0.764
J42 Unspecified chronic bronchitis
0.000 0.238 0.761
E53 Deficiency of other B group vitamins
0.000 0.240 0.760
E10.5 With peripheral circulatory complications
0.000 0.241 0.759
E10.8 With unspecified complications
0.000 0.241 0.759
E04.0 Non-toxic diffuse goitre
0.000 0.243 0.757
E20-E35 Disorders of other endocrine glands
0.000 0.251 0.749
J30.1 Allergic rhinitis due to pollen
0.000 0.261 0.739
E10.0 With coma
0.000 0.261 0.739
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.261 0.738
E27 Other disorders of adrenal gland
0.000 0.278 0.722
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
L40.1 Generalised pustular psoriasis
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.285 0.715
E03.5 Myxoedema coma
0.000 0.286 0.713
E03.4 Atrophy of thyroid (acquired)
0.000 0.286 0.713
E03.3 Postinfectious hypothyroidism
0.000 0.286 0.713
E03.1 Congenital hypothyroidism without goitre
0.000 0.286 0.713
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.286 0.713
E53.8 Deficiency of other specified B group vitamins
0.000 0.287 0.713
E03.8 Other specified hypothyroidism
0.000 0.287 0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.289 0.711
E00 Congenital iodine-deficiency syndrome
0.000 0.289 0.711
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.289 0.711
J32 Chronic sinusitis
0.000 0.289 0.711
E10.7 With multiple complications
0.000 0.289 0.711
E27.1 Primary adrenocortical insufficiency
0.000 0.291 0.709
E12 Malnutrition-related diabetes mellitus
0.000 0.295 0.705
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.297 0.703
J90 Pleural effusion, not elsewhere classified
0.000 0.299 0.701
J33.1 Polypoid sinus degeneration
0.000 0.301 0.699
E13 Other specified diabetes mellitus
0.000 0.302 0.698
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.303 0.697
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.306 0.694
J41 Simple and mucopurulent chronic bronchitis
0.000 0.308 0.692
J95-J99 Other diseases of the respiratory system
0.000 0.310 0.690
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.311 0.688
K51.5 Mucosal proctocolitis
0.000 0.313 0.687
E04.8 Other specified non-toxic goitre
0.000 0.324 0.676
M06 Other rheumatoid arthritis
0.014 0.325 0.661
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.325 0.675
E40-E46 Malnutrition
0.000 0.327 0.673
J93 Pneumothorax
0.000 0.346 0.654
K51.2 Ulcerative (chronic) proctitis
0.000 0.351 0.649
J20-J22 Other acute lower respiratory infections
0.000 0.352 0.648
J84.8 Other specified interstitial pulmonary diseases
0.000 0.353 0.647
E22 Hyperfunction of pituitary gland
0.000 0.356 0.644
E07 Other disorders of thyroid
0.000 0.357 0.643
J00-J06 Acute upper respiratory infections
0.000 0.363 0.637
K51.8 Other ulcerative colitis
0.000 0.369 0.631
E06.5 Other chronic thyroiditis
0.000 0.373 0.627
E06.4 Drug-induced thyroiditis
0.000 0.373 0.627
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.373 0.627
E06.1 Subacute thyroiditis
0.000 0.373 0.627
E06.0 Acute thyroiditis
0.000 0.373 0.627
E10.6 With other specified complications
0.000 0.374 0.626
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.378 0.622
J94 Other pleural conditions
0.000 0.383 0.617
J09-J18 Influenza and pneumonia
0.000 0.389 0.611
J37 Chronic laryngitis and laryngotracheitis
0.000 0.393 0.607
J32.9 Chronic sinusitis, unspecified
0.000 0.393 0.607
M05-M14 Inflammatory polyarthropathies
0.026 0.396 0.578
E24 Cushing's syndrome
0.000 0.397 0.603
E65-E68 Obesity and other hyperalimentation
0.000 0.400 0.600
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.403 0.597
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.407 0.593
E63 Other nutritional deficiencies
0.000 0.407 0.593
E56 Other vitamin deficiencies
0.000 0.407 0.593
E51 Thiamine deficiency
0.000 0.407 0.593
E50 Vitamin A deficiency
0.000 0.407 0.593
E60 Dietary zinc deficiency
0.000 0.407 0.593
E59 Dietary selenium deficiency
0.000 0.407 0.593
E58 Dietary calcium deficiency
0.000 0.407 0.593
E54 Ascorbic acid deficiency
0.000 0.407 0.593
E52 Niacin deficiency [pellagra]
0.000 0.407 0.593
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.407 0.592
J31.0 Chronic rhinitis
0.000 0.408 0.592
J84.0 Alveolar and parietoalveolar conditions
0.000 0.410 0.590
J31.2 Chronic pharyngitis
0.000 0.410 0.590
J80 Adult respiratory distress syndrome
0.000 0.413 0.587
E04.9 Non-toxic goitre, unspecified
0.000 0.413 0.587
J81 Pulmonary oedema
0.000 0.416 0.584
J93.1 Other spontaneous pneumothorax
0.000 0.416 0.584
M05 Seropositive rheumatoid arthritis
0.013 0.417 0.570
J91 Pleural effusion in conditions classified elsewhere
0.000 0.418 0.582
J30.2 Other seasonal allergic rhinitis
0.000 0.422 0.578
J30.0 Vasomotor rhinitis
0.000 0.422 0.578
J00 Acute nasopharyngitis [common cold]
0.000 0.423 0.577
M05.9 Seropositive rheumatoid arthritis, unspecified
0.003 0.432 0.565
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.433 0.567
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.437 0.563
E06.9 Thyroiditis, unspecified
0.000 0.437 0.562
J32.4 Chronic pansinusitis
0.000 0.439 0.561
J18 Pneumonia, organism unspecified
0.000 0.439 0.561
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.442 0.558
J20 Acute bronchitis
0.000 0.442 0.558
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.448 0.552
J30.3 Other allergic rhinitis
0.000 0.448 0.552
J95.0 Tracheostomy malfunction
0.000 0.450 0.550
E61 Deficiency of other nutrient elements
0.000 0.451 0.549
J31.1 Chronic nasopharyngitis
0.000 0.452 0.548
J43 Emphysema
0.000 0.453 0.547
E53.9 Vitamin B deficiency, unspecified
0.000 0.455 0.545
E53.1 Pyridoxine deficiency
0.000 0.455 0.545
E53.0 Riboflavin deficiency
0.000 0.455 0.545
J60-J70 Lung diseases due to external agents
0.000 0.455 0.545
E22.1 Hyperprolactinaemia
0.000 0.456 0.544
E27.2 Addisonian crisis
0.000 0.458 0.542
J95.8 Other postprocedural respiratory disorders
0.000 0.461 0.539
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.463 0.537
E32 Diseases of thymus
0.000 0.463 0.537
E31 Polyglandular dysfunction
0.000 0.463 0.537
E30 Disorders of puberty, not elsewhere classified
0.000 0.463 0.537
E25 Adrenogenital disorders
0.000 0.463 0.537
J18.9 Pneumonia, unspecified
0.000 0.464 0.536
J36 Peritonsillar abscess
0.000 0.466 0.534
M35.0 Sicca syndrome [Sjogren]
0.000 0.469 0.531
J93.8 Other pneumothorax
0.000 0.470 0.530
J85 Abscess of lung and mediastinum
0.000 0.471 0.529
K90.0 Coeliac disease
0.000 0.482 0.518
J93.0 Spontaneous tension pneumothorax
0.000 0.482 0.518
E27.5 Adrenomedullary hyperfunction
0.000 0.482 0.518
E27.0 Other adrenocortical overactivity
0.000 0.482 0.518
K50-K52 Noninfective enteritis and colitis
0.000 0.490 0.510
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.490 0.510
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.490 0.510
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.490 0.510
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.490 0.510
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.490 0.510
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.490 0.510
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.490 0.510
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.490 0.510
J32.3 Chronic sphenoidal sinusitis
0.000 0.490 0.510
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.001 0.490 0.509
H40.9 Glaucoma, unspecified
0.000 0.493 0.507
E12.9 Without complications
0.000 0.494 0.506
E12.8 With unspecified complications
0.000 0.494 0.506
E12.7 With multiple complications
0.000 0.494 0.506
E12.6 With other specified complications
0.000 0.494 0.506
E12.5 With peripheral circulatory complications
0.000 0.494 0.506
E12.4 With neurological complications
0.000 0.494 0.506
E12.3 With ophthalmic complications
0.000 0.494 0.506
E12.2 With renal complications
0.000 0.494 0.506
E12.1 With ketoacidosis
0.000 0.494 0.506
E12.0 With coma
0.000 0.494 0.506
M35 Other systemic involvement of connective tissue
0.000 0.494 0.506
H40 Glaucoma
0.000 0.494 0.506
J20.9 Acute bronchitis, unspecified
0.000 0.496 0.504
J94.2 Haemothorax
0.000 0.497 0.503
E20 Hypoparathyroidism
0.000 0.498 0.501
J32.2 Chronic ethmoidal sinusitis
0.000 0.499 0.501
E13.8 With unspecified complications
0.000 0.499 0.500
E13.7 With multiple complications
0.000 0.499 0.500
E13.6 With other specified complications
0.000 0.499 0.500
E13.5 With peripheral circulatory complications
0.000 0.499 0.500
E13.4 With neurological complications
0.000 0.499 0.500
E13.3 With ophthalmic complications
0.000 0.499 0.500
E13.2 With renal complications
0.000 0.499 0.500
E13.1 With ketoacidosis
0.000 0.499 0.500
E13.0 With coma
0.000 0.499 0.500
K90 Intestinal malabsorption
0.000 0.501 0.499
E24.9 Cushing's syndrome, unspecified
0.000 0.502 0.498
J01 Acute sinusitis
0.000 0.502 0.498
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.504 0.496
J41.1 Mucopurulent chronic bronchitis
0.000 0.504 0.496
J41.0 Simple chronic bronchitis
0.000 0.504 0.496
J96 Respiratory failure, not elsewhere classified
0.000 0.505 0.495
E13.9 Without complications
0.000 0.507 0.493
E55 Vitamin D deficiency
0.000 0.507 0.493
E22.0 Acromegaly and pituitary gigantism
0.000 0.509 0.491
H40-H42 Glaucoma
0.000 0.509 0.491
E26 Hyperaldosteronism
0.000 0.512 0.488
J10 Influenza due to identified influenza virus
0.000 0.512 0.488
J32.8 Other chronic sinusitis
0.000 0.514 0.486
E14 Unspecified diabetes mellitus
0.000 0.514 0.485
J39 Other diseases of upper respiratory tract
0.000 0.515 0.485
# Top node
0.000 0.515 0.485
M06.8 Other specified rheumatoid arthritis
0.010 0.516 0.474
M06.2 Rheumatoid bursitis
0.010 0.516 0.474
M06.1 Adult-onset Still's disease
0.010 0.516 0.474
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.517 0.483
E45 Retarded development following protein-energy malnutrition
0.000 0.517 0.483
E43 Unspecified severe protein-energy malnutrition
0.000 0.517 0.483
E42 Marasmic kwashiorkor
0.000 0.517 0.483
E41 Nutritional marasmus
0.000 0.517 0.483
E40 Kwashiorkor
0.000 0.517 0.483
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.519 0.481
Chapter VII Diseases of the eye and adnexa
0.000 0.519 0.481
Chapter XI Diseases of the digestive system
0.000 0.521 0.479
E07.8 Other specified disorders of thyroid
0.000 0.522 0.478
J18.0 Bronchopneumonia, unspecified
0.000 0.523 0.477
M35.3 Polymyalgia rheumatica
0.000 0.523 0.477
E27.8 Other specified disorders of adrenal gland
0.000 0.525 0.475
J30.4 Allergic rhinitis, unspecified
0.000 0.525 0.475
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.526 0.474
K90-K93 Other diseases of the digestive system
0.000 0.526 0.474
J21 Acute bronchiolitis
0.000 0.530 0.470
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.020 0.535 0.445
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.536 0.464
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.538 0.462
E22.8 Other hyperfunction of pituitary gland
0.000 0.538 0.462
H40.1 Primary open-angle glaucoma
0.000 0.538 0.462
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.539 0.461
E07.1 Dyshormogenetic goitre
0.000 0.539 0.461
E07.0 Hypersecretion of calcitonin
0.000 0.539 0.461
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.539 0.461
H30-H36 Disorders of choroid and retina
0.000 0.540 0.460
J46 Status asthmaticus
0.000 0.542 0.458
E29 Testicular dysfunction
0.000 0.545 0.455
J32.1 Chronic frontal sinusitis
0.000 0.545 0.455
J11 Influenza, virus not identified
0.000 0.546 0.454
E46 Unspecified protein-energy malnutrition
0.000 0.549 0.450
H36 Retinal disorders in diseases classified elsewhere
0.000 0.551 0.449
J94.8 Other specified pleural conditions
0.000 0.552 0.448
M14 Arthropathies in other diseases classified elsewhere
0.017 0.553 0.430
J95.5 Postprocedural subglottic stenosis
0.000 0.554 0.446
J95.4 Mendelson's syndrome
0.000 0.554 0.446
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.554 0.446
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.554 0.446
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.554 0.446
E28 Ovarian dysfunction
0.000 0.557 0.443
J94.9 Pleural condition, unspecified
0.000 0.557 0.443
J94.0 Chylous effusion
0.000 0.557 0.443
K70-K77 Diseases of liver
0.000 0.558 0.442
M20-M25 Other joint disorders
0.000 0.558 0.442
H36.0 Diabetic retinopathy
0.000 0.559 0.441
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.562 0.438
J09 Influenza due to certain identified influenza virus
0.000 0.562 0.438
E34 Other endocrine disorders
0.000 0.563 0.437
M11 Other crystal arthropathies
0.016 0.564 0.420
E14.3 With ophthalmic complications
0.000 0.564 0.436
J37.1 Chronic laryngotracheitis
0.000 0.565 0.435
M12 Other specific arthropathies
0.019 0.566 0.415
M09 Juvenile arthritis in diseases classified elsewhere
0.019 0.566 0.415
M08 Juvenile arthritis
0.019 0.566 0.415
E24.8 Other Cushing's syndrome
0.000 0.567 0.432
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.567 0.432
E24.3 Ectopic ACTH syndrome
0.000 0.567 0.432
E24.2 Drug-induced Cushing's syndrome
0.000 0.567 0.432
E24.1 Nelson's syndrome
0.000 0.567 0.432
E24.0 Pituitary-dependent Cushing's disease
0.000 0.567 0.432
M06.4 Inflammatory polyarthropathy
0.010 0.568 0.422
M06.3 Rheumatoid nodule
0.010 0.569 0.421
E27.9 Disorder of adrenal gland, unspecified
0.000 0.569 0.431
E67 Other hyperalimentation
0.000 0.569 0.430
E68 Sequelae of hyperalimentation
0.000 0.569 0.430
J43.2 Centrilobular emphysema
0.000 0.573 0.427
E65 Localised adiposity
0.000 0.574 0.426
K90.9 Intestinal malabsorption, unspecified
0.000 0.574 0.426
J40 Bronchitis, not specified as acute or chronic
0.000 0.574 0.426
H40.5 Glaucoma secondary to other eye disorders
0.000 0.575 0.425
E50.9 Vitamin A deficiency, unspecified
0.000 0.575 0.425
E50.8 Other manifestations of vitamin A deficiency
0.000 0.575 0.425
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.575 0.425
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.575 0.425
E50.5 Vitamin A deficiency with night blindness
0.000 0.575 0.425
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.575 0.425
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.575 0.425
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.575 0.425
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.575 0.425
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.575 0.425
E51.9 Thiamine deficiency, unspecified
0.000 0.575 0.425
E51.8 Other manifestations of thiamine deficiency
0.000 0.575 0.425
E51.2 Wernicke's encephalopathy
0.000 0.575 0.425
E51.1 Beriberi
0.000 0.575 0.425
E56.9 Vitamin deficiency, unspecified
0.000 0.575 0.425
E56.8 Deficiency of other vitamins
0.000 0.575 0.425
E56.1 Deficiency of vitamin K
0.000 0.575 0.425
E56.0 Deficiency of vitamin E
0.000 0.575 0.425
E63.9 Nutritional deficiency, unspecified
0.000 0.575 0.425
E63.8 Other specified nutritional deficiencies
0.000 0.575 0.425
E63.1 Imbalance of constituents of food intake
0.000 0.575 0.425
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.575 0.425
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.575 0.425
E64.8 Sequelae of other nutritional deficiencies
0.000 0.575 0.425
E64.3 Sequelae of rickets
0.000 0.575 0.425
E64.2 Sequelae of vitamin C deficiency
0.000 0.575 0.425
E64.1 Sequelae of vitamin A deficiency
0.000 0.575 0.425
E64.0 Sequelae of protein-energy malnutrition
0.000 0.575 0.425
J85.2 Abscess of lung without pneumonia
0.000 0.575 0.425
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.575 0.425
J18.8 Other pneumonia, organism unspecified
0.000 0.577 0.423
K75 Other inflammatory liver diseases
0.000 0.580 0.420
Chapter VIII Diseases of the ear and mastoid process
0.000 0.580 0.420
J12 Viral pneumonia, not elsewhere classified
0.000 0.581 0.419
J03 Acute tonsillitis
0.000 0.582 0.418
M05.8 Other seropositive rheumatoid arthritis
0.009 0.582 0.409
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.009 0.582 0.409
M05.2 Rheumatoid vasculitis
0.009 0.582 0.409
M05.1 Rheumatoid lung disease
0.009 0.582 0.409
M05.0 Felty's syndrome
0.009 0.582 0.409
J17 Pneumonia in diseases classified elsewhere
0.000 0.582 0.418
J94.1 Fibrothorax
0.000 0.587 0.413
E61.1 Iron deficiency
0.000 0.587 0.413
L40-L45 Papulosquamous disorders
0.307 0.588 0.104
E04.1 Non-toxic single thyroid nodule
0.000 0.590 0.410
M07 Psoriatic and enteropathic arthropathies
0.161 0.591 0.248
H33 Retinal detachments and breaks
0.000 0.592 0.408
H60-H62 Diseases of external ear
0.000 0.592 0.408
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.002 0.593 0.405
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.002 0.593 0.405
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.002 0.593 0.405
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.002 0.593 0.405
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.002 0.593 0.405
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.002 0.593 0.405
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.002 0.593 0.405
J32.0 Chronic maxillary sinusitis
0.000 0.593 0.407
J86 Pyothorax
0.000 0.594 0.406
H43-H45 Disorders of vitreous body and globe
0.000 0.595 0.405
H61 Other disorders of external ear
0.000 0.596 0.404
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.002 0.597 0.401
J18.2 Hypostatic pneumonia, unspecified
0.000 0.598 0.402
M34 Systemic sclerosis
0.000 0.598 0.402
E15 Nondiabetic hypoglycaemic coma
0.000 0.600 0.400
J20.7 Acute bronchitis due to echovirus
0.000 0.600 0.400
J20.6 Acute bronchitis due to rhinovirus
0.000 0.600 0.400
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.600 0.400
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.600 0.400
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.600 0.400
J20.2 Acute bronchitis due to streptococcus
0.000 0.600 0.400
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.600 0.400
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.600 0.400
K75.4 Autoimmune hepatitis
0.000 0.600 0.400
H61.2 Impacted cerumen
0.000 0.605 0.395
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.606 0.394
E61.9 Deficiency of nutrient element, unspecified
0.000 0.606 0.393
E61.8 Deficiency of other specified nutrient elements
0.000 0.606 0.393
E61.7 Deficiency of multiple nutrient elements
0.000 0.606 0.393
E61.6 Vanadium deficiency
0.000 0.606 0.393
E61.5 Molybdenum deficiency
0.000 0.606 0.393
E61.4 Chromium deficiency
0.000 0.606 0.393
E61.3 Manganese deficiency
0.000 0.606 0.393
E61.0 Copper deficiency
0.000 0.606 0.393
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.607 0.393
J43.8 Other emphysema
0.000 0.608 0.392
J43.1 Panlobular emphysema
0.000 0.608 0.392
J43.0 MacLeod's syndrome
0.000 0.608 0.392
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.609 0.391
J66 Airway disease due to specific organic dust
0.000 0.609 0.391
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.609 0.391
J62 Pneumoconiosis due to dust containing silica
0.000 0.609 0.391
J65 Pneumoconiosis associated with tuberculosis
0.000 0.609 0.391
J64 Unspecified pneumoconiosis
0.000 0.609 0.391
J60 Coalworker's pneumoconiosis
0.000 0.609 0.391
H33.0 Retinal detachment with retinal break
0.000 0.609 0.391
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.610 0.390
J69 Pneumonitis due to solids and liquids
0.000 0.611 0.389
M35.1 Other overlap syndromes
0.000 0.614 0.386
E25.9 Adrenogenital disorder, unspecified
0.000 0.614 0.385
E25.8 Other adrenogenital disorders
0.000 0.614 0.385
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.614 0.385
E30.9 Disorder of puberty, unspecified
0.000 0.614 0.385
E30.8 Other disorders of puberty
0.000 0.614 0.385
E30.1 Precocious puberty
0.000 0.614 0.385
E30.0 Delayed puberty
0.000 0.614 0.385
E31.9 Polyglandular dysfunction, unspecified
0.000 0.614 0.385
E31.8 Other polyglandular dysfunction
0.000 0.614 0.385
E31.1 Polyglandular hyperfunction
0.000 0.614 0.385
E31.0 Autoimmune polyglandular failure
0.000 0.614 0.385
E32.9 Disease of thymus, unspecified
0.000 0.614 0.385
E32.8 Other diseases of thymus
0.000 0.614 0.385
E32.1 Abscess of thymus
0.000 0.614 0.385
E32.0 Persistent hyperplasia of thymus
0.000 0.614 0.385
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.614 0.385
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.614 0.385
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.614 0.385
J01.9 Acute sinusitis, unspecified
0.000 0.618 0.382
K74 Fibrosis and cirrhosis of liver
0.000 0.620 0.380
J85.3 Abscess of mediastinum
0.000 0.620 0.379
J85.1 Abscess of lung with pneumonia
0.000 0.620 0.379
J85.0 Gangrene and necrosis of lung
0.000 0.620 0.379
J01.0 Acute maxillary sinusitis
0.000 0.623 0.377
K73 Chronic hepatitis, not elsewhere classified
0.000 0.626 0.374
J20.8 Acute bronchitis due to other specified organisms
0.000 0.630 0.370
H40.2 Primary angle-closure glaucoma
0.000 0.632 0.368
E07.9 Disorder of thyroid, unspecified
0.000 0.633 0.367
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.634 0.366
J04 Acute laryngitis and tracheitis
0.000 0.635 0.364
K74.3 Primary biliary cirrhosis
0.000 0.635 0.365
J38.2 Nodules of vocal cords
0.000 0.636 0.364
J39.9 Disease of upper respiratory tract, unspecified
0.000 0.637 0.363
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.637 0.363
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.637 0.363
M35.5 Multifocal fibrosclerosis
0.000 0.637 0.363
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.637 0.363
M35.2 Behcet's disease
0.000 0.637 0.363
H40.6 Glaucoma secondary to drugs
0.000 0.637 0.363
H40.4 Glaucoma secondary to eye inflammation
0.000 0.637 0.363
H40.3 Glaucoma secondary to eye trauma
0.000 0.637 0.363
M31 Other necrotising vasculopathies
0.000 0.637 0.363
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.000 0.638 0.362
M07.3 Other psoriatic arthropathies
0.349 0.639 0.012
E20.8 Other hypoparathyroidism
0.000 0.640 0.360
E20.1 Pseudohypoparathyroidism
0.000 0.640 0.360
E20.0 Idiopathic hypoparathyroidism
0.000 0.640 0.360
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.641 0.359
H43 Disorders of vitreous body
0.000 0.642 0.358
H33.1 Retinoschisis and retinal cysts
0.000 0.642 0.358
J45 Asthma
0.000 0.642 0.358
K90.8 Other intestinal malabsorption
0.000 0.642 0.358
K90.3 Pancreatic steatorrhoea
0.000 0.642 0.358
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.642 0.358
K90.1 Tropical sprue
0.000 0.642 0.358
J01.8 Other acute sinusitis
0.000 0.643 0.357
J01.4 Acute pansinusitis
0.000 0.643 0.357
J01.3 Acute sphenoidal sinusitis
0.000 0.643 0.357
J01.2 Acute ethmoidal sinusitis
0.000 0.643 0.357
J01.1 Acute frontal sinusitis
0.000 0.643 0.357
E23 Hypofunction and other disorders of pituitary gland
0.000 0.644 0.355
H40.8 Other glaucoma
0.000 0.645 0.355
J37.0 Chronic laryngitis
0.000 0.645 0.355
J96.9 Respiratory failure, unspecified
0.000 0.645 0.355
J96.1 Chronic respiratory failure
0.000 0.645 0.355
J96.0 Acute respiratory failure
0.000 0.645 0.355
J38.0 Paralysis of vocal cords and larynx
0.000 0.646 0.354
E55.0 Rickets, active
0.000 0.647 0.353
H10-H13 Disorders of conjunctiva
0.000 0.648 0.352
H42 Glaucoma in diseases classified elsewhere
0.000 0.648 0.352
E26.9 Hyperaldosteronism, unspecified
0.000 0.650 0.350
E26.8 Other hyperaldosteronism
0.000 0.650 0.350
E26.1 Secondary hyperaldosteronism
0.000 0.650 0.350
J35 Chronic diseases of tonsils and adenoids
0.000 0.650 0.350
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.650 0.350
M30 Polyarteritis nodosa and related conditions
0.000 0.650 0.350
M07.30 Other psoriatic arthropathies (Multiple sites)
0.348 0.650 0.002
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.651 0.349
E14.7 With multiple complications
0.000 0.652 0.348
E14.6 With other specified complications
0.000 0.652 0.348
E14.2 Withrenal complications
0.000 0.652 0.348
E14.1 With ketoacidosis
0.000 0.652 0.348
E14.0 With coma
0.000 0.652 0.348
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified
0.000 0.652 0.348
J39.1 Other abscess of pharynx
0.000 0.652 0.348
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.652 0.348
K35-K38 Diseases of appendix
0.000 0.653 0.347
M06.19 Adult-onset Still's disease (Site unspecified)
0.008 0.653 0.340
M06.18 Adult-onset Still's disease (Other)
0.008 0.653 0.340
M06.17 Adult-onset Still's disease (Ankle and foot)
0.008 0.653 0.340
M06.16 Adult-onset Still's disease (Lower leg)
0.008 0.653 0.340
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.008 0.653 0.340
M06.14 Adult-onset Still's disease (Hand)
0.008 0.653 0.340
M06.13 Adult-onset Still's disease (Forearm)
0.008 0.653 0.340
M06.12 Adult-onset Still's disease (Upper arm)
0.008 0.653 0.340
M06.11 Adult-onset Still's disease (Shoulder region)
0.008 0.653 0.340
M06.10 Adult-onset Still's disease (Multiple sites)
0.008 0.653 0.340
M06.29 Rheumatoid bursitis (Site unspecified)
0.008 0.653 0.340
M06.28 Rheumatoid bursitis (Other)
0.008 0.653 0.340
M06.27 Rheumatoid bursitis (Ankle and foot)
0.008 0.653 0.340
M06.26 Rheumatoid bursitis (Lower leg)
0.008 0.653 0.340

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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