TreeWAS – Variant ID: rs10159528

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23 Internal derangement of knee	0.578	0.422	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.575	0.425	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.571	0.429	0.000
M23.4 Loose body in knee	0.568	0.432	0.000
M23.49 Loose body in knee-Unspec lig/men	0.566	0.434	0.000
M23.3 Other meniscus derangements	0.566	0.434	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.565	0.435	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.524	0.476	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.504	0.496	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.502	0.498	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.496	0.504	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.490	0.510	0.000
M23.0 Cystic meniscus	0.486	0.514	0.000
M23.5 Chronic instability of knee	0.454	0.546	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.448	0.552	0.000
M23.40 Loose body in knee-Mult sites	0.415	0.585	0.000
M20-M25 Other joint disorders	0.414	0.586	0.000
M22 Disorders of patella	0.414	0.586	0.000
M23.43 Loose body in knee-Med lig/oth men	0.413	0.587	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.409	0.591	0.000
M23.47 Loose body in knee-Capsular lig	0.408	0.592	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.408	0.592	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.408	0.592	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.407	0.593	0.000
M23.1 Discoid meniscus (congenital)	0.407	0.593	0.000
M23.37 Other meniscus derangements-Capsular lig	0.406	0.594	0.000
M22.4 Chondromalacia patellae	0.392	0.608	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.392	0.608	0.000
M24 Other specific joint derangements	0.391	0.609	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.391	0.609	0.000
M24.1 Other articular cartilage disorders	0.386	0.614	0.000
M23.8 Other internal derangements of knee	0.379	0.621	0.000
M22.2 Patellofemoral disorders	0.377	0.623	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.377	0.623	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.377	0.623	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.371	0.629	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.368	0.632	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.364	0.635	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.364	0.636	0.000
M31 Other necrotising vasculopathies	0.363	0.637	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.362	0.638	0.000
M23.46 Loose body in knee-O/unsp lat men	0.353	0.646	0.000
M23.07 Cystic meniscus-Capsular lig	0.349	0.651	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.349	0.651	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.349	0.651	0.000
M23.00 Cystic meniscus (Multiple sites)	0.349	0.651	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.344	0.656	0.000
M32 Systemic lupus erythematosus	0.342	0.658	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.341	0.659	0.000
M22.8 Other disorders of patella	0.336	0.664	0.000
M22.3 Other derangements of patella	0.330	0.670	0.000
M24.5 Contracture of joint	0.327	0.673	0.000
M23.9 Internal derangement of knee, unspecified	0.326	0.674	0.000
M31.3 Wegener's granulomatosis	0.326	0.674	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.325	0.675	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.325	0.675	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.325	0.675	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.325	0.675	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.325	0.675	0.000
M34 Systemic sclerosis	0.320	0.680	0.000
M24.6 Ankylosis of joint	0.317	0.683	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.310	0.689	0.000
M22.0 Recurrent dislocation of patella	0.310	0.690	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.307	0.692	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.304	0.696	0.000
M31.8 Other specified necrotising vasculopathies	0.302	0.698	0.000
M22.9 Disorder of patella, unspecified	0.302	0.698	0.000
M24.7 Protrusio acetabuli	0.298	0.702	0.000
M22.1 Recurrent subluxation of patella	0.297	0.703	0.000
M24.0 Loose body in joint	0.294	0.706	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.292	0.708	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.292	0.708	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.292	0.708	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.292	0.708	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.292	0.708	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.292	0.708	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.292	0.708	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.292	0.708	0.000
M24.14 Other articular cartilage disorders (Hand)	0.292	0.708	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.289	0.711	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.287	0.713	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.287	0.713	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.284	0.716	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.281	0.719	0.000
M24.9 Joint derangement, unspecified	0.281	0.719	0.000
M31.9 Necrotising vasculopathy, unspecified	0.280	0.720	0.000
M32.8 Other forms of systemic lupus erythematosus	0.277	0.723	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.277	0.723	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.277	0.723	0.000
M24.18 Other articular cartilage disorders (Other)	0.277	0.723	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.277	0.723	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.277	0.723	0.000
M31.0 Hypersensitivity angiitis	0.274	0.726	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.272	0.728	0.000
M24.56 Contracture of joint (Lower leg)	0.272	0.728	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.269	0.731	0.000
M31.1 Thrombotic microangiopathy	0.265	0.735	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.263	0.737	0.000
M31.2 Lethal midline granuloma	0.260	0.740	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.258	0.742	0.000
M24.52 Contracture of joint (Upper arm)	0.257	0.743	0.000
M34.8 Other forms of systemic sclerosis	0.256	0.744	0.000
M31.7 Microscopic polyangiitis	0.255	0.745	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.253	0.747	0.000
M24.57 Contracture of joint (Ankle and foot)	0.252	0.748	0.000
M24.66 Ankylosis of joint (Lower leg)	0.251	0.749	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.249	0.751	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.248	0.752	0.000
M24.01 Loose body in joint (Shoulder region)	0.247	0.753	0.000
M34.9 Systemic sclerosis, unspecified	0.247	0.753	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.245	0.755	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.245	0.755	0.000
M34.0 Progressive systemic sclerosis	0.245	0.755	0.000
M30 Polyarteritis nodosa and related conditions	0.239	0.761	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.238	0.761	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.238	0.761	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.236	0.764	0.000
M24.59 Contracture of joint (Site unspecified)	0.235	0.765	0.000
M24.58 Contracture of joint (Other)	0.235	0.765	0.000
M24.53 Contracture of joint (Forearm)	0.235	0.765	0.000
M24.50 Contracture of joint (Multiple sites)	0.235	0.765	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.234	0.766	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.234	0.766	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.234	0.766	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.234	0.766	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.234	0.766	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.234	0.766	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.234	0.766	0.000
M24.07 Loose body in joint (Ankle and foot)	0.234	0.766	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.233	0.767	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.231	0.769	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.230	0.770	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.227	0.772	0.000
M24.68 Ankylosis of joint (Other)	0.227	0.772	0.000
M24.63 Ankylosis of joint (Forearm)	0.227	0.772	0.000
M24.62 Ankylosis of joint (Upper arm)	0.227	0.772	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.227	0.772	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.227	0.772	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.226	0.774	0.000
M24.2 Disorder of ligament	0.225	0.775	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.223	0.777	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.223	0.777	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.223	0.777	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.223	0.777	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.223	0.777	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.223	0.777	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.223	0.777	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.223	0.777	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.222	0.777	0.000
M24.03 Loose body in joint (Forearm)	0.221	0.779	0.000
M24.64 Ankylosis of joint (Hand)	0.221	0.779	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.221	0.779	0.000
M31.6 Other giant cell arteritis	0.218	0.782	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.217	0.783	0.000
M24.79 Protrusio acetabuli-Site unspec	0.214	0.786	0.000
M24.78 Protrusio acetabuli-Other	0.214	0.786	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.214	0.786	0.000
M24.76 Protrusio acetabuli-Lower leg	0.214	0.786	0.000
M24.74 Protrusio acetabuli-Hand	0.214	0.786	0.000
M24.73 Protrusio acetabuli-Forearm	0.214	0.786	0.000
M24.72 Protrusio acetabuli-Upper arm	0.214	0.786	0.000
M24.71 Protrusio acetabuli-Shldr region	0.214	0.786	0.000
M24.70 Protrusio acetabuli-Mult sites	0.214	0.786	0.000
M24.04 Loose body in joint (Hand)	0.214	0.786	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.213	0.787	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.212	0.787	0.000
M24.09 Loose body in joint (Site unspecified)	0.211	0.789	0.000
M24.08 Loose body in joint (Other)	0.211	0.789	0.000
M24.00 Loose body in joint (Multiple sites)	0.211	0.789	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.208	0.792	0.000
M24.54 Contracture of joint (Hand)	0.207	0.793	0.000
M33 Dermatopolymyositis	0.206	0.793	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.206	0.794	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.206	0.794	0.000
M36.3 Arthropathy in other blood disorders	0.206	0.794	0.000
M36.2 Haemophilic arthropathy	0.206	0.794	0.000
M36.1 Arthropathy in neoplastic disease	0.206	0.794	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.206	0.794	0.000
M21 Other acquired deformities of limbs	0.202	0.797	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.202	0.798	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.201	0.798	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.201	0.798	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.201	0.798	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.201	0.798	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.201	0.798	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.201	0.798	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.201	0.798	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.201	0.798	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.201	0.798	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.201	0.798	0.000
M24.98 Joint derangement, unspecified (Other)	0.201	0.798	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.201	0.798	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.201	0.798	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.201	0.798	0.000
M24.94 Joint derangement, unspecified (Hand)	0.201	0.798	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.201	0.798	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.201	0.798	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.201	0.798	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.201	0.798	0.000
M24.06 Loose body in joint-Lower leg	0.200	0.800	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.196	0.804	0.000
M24.28 Disorder of ligament (Other)	0.188	0.812	0.000
M24.51 Contracture of joint (Shoulder region)	0.187	0.813	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.184	0.815	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.181	0.818	0.000
M34.1 CR(E)ST syndrome	0.180	0.820	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.177	0.823	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.176	0.824	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.174	0.826	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.174	0.826	0.000
M24.21 Disorder of ligament (Shoulder region)	0.173	0.826	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.171	0.828	0.000
M30.2 Juvenile polyarteritis	0.171	0.828	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.171	0.829	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.164	0.835	0.001
M21.7 Unequal limb length (acquired)	0.163	0.837	0.000
M24.02 Loose body in joint (Upper arm)	0.162	0.837	0.000
M24.29 Disorder of ligament (Site unspecified)	0.161	0.838	0.000
M24.22 Disorder of ligament (Upper arm)	0.161	0.838	0.000
M24.20 Disorder of ligament (Multiple sites)	0.161	0.838	0.000
M24.23 Disorder of ligament (Forearm)	0.161	0.839	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.158	0.842	0.000
M21.3 Wrist or foot drop (acquired)	0.155	0.845	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.151	0.848	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.149	0.851	0.000
M33.9 Dermatopolymyositis, unspecified	0.148	0.852	0.000
M33.0 Juvenile dermatomyositis	0.148	0.852	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.148	0.852	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.147	0.852	0.001
M30.0 Polyarteritis nodosa	0.139	0.860	0.000
M21.6 Other acquired deformities of ankle and foot	0.138	0.862	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.131	0.869	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.131	0.869	0.000
M33.1 Other dermatomyositis	0.130	0.870	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.130	0.870	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.130	0.870	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.130	0.870	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.130	0.870	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.130	0.870	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.130	0.870	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.130	0.870	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.130	0.870	0.000
M21.8 Other specified acquired deformities of limbs	0.130	0.870	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.129	0.871	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.127	0.873	0.000
M21.9 Acquired deformity of limb, unspecified	0.125	0.875	0.000
M21.1 Varus deformity, not elsewhere classified	0.119	0.881	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.119	0.881	0.001
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.118	0.881	0.001
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.118	0.881	0.001
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.118	0.881	0.001
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.118	0.881	0.001
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.118	0.881	0.001
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.118	0.881	0.001
M21.0 Valgus deformity, not elsewhere classified	0.118	0.882	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.117	0.882	0.001
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.117	0.883	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.117	0.883	0.000
M21.78 Unequal limb length (acquired)-Other	0.117	0.883	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.117	0.883	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.117	0.883	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.117	0.883	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.117	0.883	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.117	0.883	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.116	0.884	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.111	0.889	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.111	0.889	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.111	0.889	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.111	0.889	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.111	0.889	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.111	0.889	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.111	0.889	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.111	0.889	0.000
M21.4 Flat foot [pes planus] (acquired)	0.111	0.889	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.107	0.892	0.001
M24.24 Disorder of ligament (Hand)	0.108	0.892	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.107	0.892	0.001
M24.26 Disorder of ligament (Lower leg)	0.107	0.893	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.106	0.894	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.100	0.900	0.001
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.099	0.900	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.099	0.900	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.099	0.900	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.099	0.900	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.099	0.900	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.099	0.900	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.099	0.900	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.099	0.900	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.099	0.900	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.099	0.901	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.097	0.903	0.000
M21.2 Flexion deformity	0.096	0.903	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.095	0.905	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.093	0.906	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.093	0.906	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.093	0.906	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.093	0.906	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.093	0.906	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.093	0.906	0.000
M33.2 Polymyositis	0.092	0.907	0.001
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.092	0.908	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.092	0.908	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.090	0.910	0.001
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.089	0.910	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.089	0.910	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.089	0.910	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.089	0.910	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.089	0.910	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.089	0.910	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.089	0.910	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.089	0.910	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.085	0.914	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.085	0.914	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.085	0.914	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.085	0.914	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.085	0.914	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.085	0.914	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.085	0.914	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.085	0.915	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.085	0.915	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.085	0.915	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.085	0.915	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.085	0.915	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.085	0.915	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.085	0.915	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.085	0.915	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.084	0.915	0.001
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.084	0.915	0.001
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.082	0.917	0.001
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.082	0.918	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.082	0.918	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.081	0.918	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.081	0.919	0.001
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.080	0.920	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.080	0.920	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.080	0.920	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.080	0.920	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.080	0.920	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.080	0.920	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.080	0.920	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.080	0.920	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.080	0.920	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.079	0.920	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.076	0.924	0.000
M21.23 Flexion deformity (Forearm)	0.070	0.929	0.000
M35 Other systemic involvement of connective tissue	0.069	0.930	0.001
M21.29 Flexion deformity (Site unspecified)	0.069	0.930	0.000
M21.28 Flexion deformity (Other)	0.069	0.930	0.000
M21.21 Flexion deformity (Shoulder region)	0.069	0.930	0.000
M21.20 Flexion deformity (Multiple sites)	0.069	0.930	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.068	0.931	0.001
M21.27 Flexion deformity (Ankle and foot)	0.067	0.933	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.064	0.935	0.001
M21.22 Flexion deformity (Upper arm)	0.064	0.936	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.062	0.938	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.060	0.938	0.001
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.057	0.943	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.055	0.944	0.001
M35.9 Systemic involvement of connective tissue, unspecified	0.050	0.950	0.001
M35.6 Relapsing panniculitis [Weber-Christian]	0.050	0.950	0.001
M35.5 Multifocal fibrosclerosis	0.050	0.950	0.001
M35.4 Diffuse (eosinophilic) fasciitis	0.050	0.950	0.001
M21.24 Flexion deformity (Hand)	0.050	0.950	0.000
M35.3 Polymyalgia rheumatica	0.049	0.951	0.000
M21.26 Flexion deformity (Lower leg)	0.049	0.951	0.000
M35.2 Behcet's disease	0.048	0.951	0.000
M35.8 Other specified systemic involvement of connective tissue	0.047	0.953	0.001
M23.30 Other meniscus derangements (Multiple sites)	0.045	0.954	0.001
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.045	0.954	0.001
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.043	0.956	0.001
M35.1 Other overlap syndromes	0.040	0.959	0.001
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.036	0.964	0.001
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.033	0.965	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.032	0.967	0.002
M35.7 Hypermobility syndrome	0.029	0.970	0.001
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.976	0.024
R25 Abnormal involuntary movements	0.000	0.977	0.023
R25.1 Tremor, unspecified	0.000	0.977	0.023
R25.2 Cramp and spasm	0.000	0.979	0.021
M13.94 Arthritis, unspecified (Hand)	0.000	0.982	0.018
R25.0 Abnormal head movements	0.000	0.983	0.017
R25.3 Fasciculation	0.000	0.984	0.016
G95.9 Disease of spinal cord, unspecified	0.000	0.986	0.014
R27.0 Ataxia, unspecified	0.000	0.987	0.013
G95.2 Cord compression, unspecified	0.000	0.987	0.013
G95 Other diseases of spinal cord	0.000	0.987	0.013
G95.8 Other specified diseases of spinal cord	0.000	0.987	0.013
R27 Other lack of coordination	0.000	0.988	0.012
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.990	0.010
G95.0 Syringomyelia and syringobulbia	0.000	0.990	0.010
R27.8 Other and unspecified lack of coordination	0.000	0.990	0.010
G82.2 Paraplegia, unspecified	0.000	0.991	0.009
Z98.1 Arthrodesis status	0.000	0.991	0.009
Z98.8 Other specified postsurgical states	0.000	0.992	0.008
O14.9 Preeclampsia, unspecified	0.000	0.992	0.008
D09.0 Bladder	0.007	0.993	0.000
G95.1 Vascular myelopathies	0.000	0.993	0.006
R59.1 Generalised enlarged lymph nodes	0.006	0.994	0.000
Z98 Other postsurgical states	0.000	0.994	0.006
D37.4 Colon	0.000	0.994	0.006
D37.1 Stomach	0.000	0.994	0.006
G82 Paraplegia and tetraplegia	0.000	0.994	0.006
D37.5 Rectum	0.000	0.995	0.005
G82.5 Tetraplegia, unspecified	0.000	0.995	0.005
R59.9 Enlarged lymph nodes, unspecified	0.000	0.995	0.005
M35.0 Sicca syndrome [Sjogren]	0.004	0.995	0.001
D25.0 Submucous leiomyoma of uterus	0.000	0.995	0.005
M13.93 Arthritis, unspecified (Forearm)	0.000	0.995	0.005
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.995	0.005
G82.4 Spastic tetraplegia	0.000	0.995	0.005
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.995	0.005
D37.9 Digestive organ, unspecified	0.000	0.995	0.004
G82.3 Flaccid tetraplegia	0.000	0.996	0.004
G82.0 Flaccid paraplegia	0.000	0.996	0.004
M13.9 Arthritis, unspecified	0.000	0.996	0.004
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.996	0.004
S80.9 Superficial injury of lower leg, unspecified	0.000	0.996	0.004
G82.1 Spastic paraplegia	0.000	0.996	0.004
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.996	0.004
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.996	0.004
D37.0 Lip, oral cavity and pharynx	0.000	0.996	0.003
N30.0 Acute cystitis	0.000	0.996	0.004
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.996	0.004
D37.3 Appendix	0.000	0.997	0.003
I27.2 Other secondary pulmonary hypertension	0.000	0.997	0.003
D37.2 Small intestine	0.000	0.997	0.003
D37.6 Liver, gallbladder and bile ducts	0.000	0.997	0.003
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.003	0.997	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.997	0.003
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.997	0.003
M13.98 Arthritis, unspecified (Other)	0.000	0.997	0.003
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.997	0.003
G50.0 Trigeminal neuralgia	0.000	0.997	0.003
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
D09 Carcinoma in situ of other and unspecified sites	0.003	0.997	0.000
T17.2 Foreign body in pharynx	0.003	0.997	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
R57.2 Septic shock	0.002	0.998	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.002	0.998	0.000
O14.2 HELLP syndrome	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.000	0.998	0.002
M20 Acquired deformities of fingers and toes	0.002	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.002	0.998	0.000
T17.5 Foreign body in bronchus	0.002	0.998	0.000
D37.7 Other digestive organs	0.000	0.998	0.002
T17.3 Foreign body in larynx	0.002	0.998	0.000
T17 Foreign body in respiratory tract	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.002	0.998	0.000
M13 Other arthritis	0.000	0.998	0.002
S22.50 Flail chest (closed)	0.000	0.998	0.002
S36.00 Injury of spleen (without open wound into cavity)	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.998	0.002
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
M13.89 Other specified arthritis (Site unspecified)	0.000	0.998	0.002
M13.8 Other specified arthritis	0.000	0.998	0.002
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.002	0.998	0.000
Z63.0 Problems in relationship with spouse or partner	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.000	0.998	0.002
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.998	0.002
R26 Abnormalities of gait and mobility	0.000	0.998	0.002
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
T17.4 Foreign body in trachea	0.002	0.998	0.000
T17.1 Foreign body in nostril	0.002	0.998	0.000
T17.0 Foreign body in nasal sinus	0.002	0.998	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.002	0.998	0.000
V22.4 Driver injured in traffic accident	0.002	0.998	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.998	0.002
J39.8 Other specified diseases of upper respiratory tract	0.002	0.998	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.002	0.998	0.000
M13.1 Monoarthritis, not elsewhere classified	0.000	0.998	0.002
H40.2 Primary angle-closure glaucoma	0.002	0.998	0.000
Z93.2 Ileostomy status	0.000	0.998	0.002
M13.86 Other specified arthritis (Lower leg)	0.000	0.998	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.002
M13.88 Other specified arthritis (Other)	0.000	0.998	0.002
M13.85 Other specified arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M13.84 Other specified arthritis (Hand)	0.000	0.998	0.002
M13.83 Other specified arthritis (Forearm)	0.000	0.998	0.002
M13.82 Other specified arthritis (Upper arm)	0.000	0.998	0.002
M13.81 Other specified arthritis (Shoulder region)	0.000	0.998	0.002
M13.80 Other specified arthritis (Multiple sites)	0.000	0.998	0.002
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.998	0.002
H61.2 Impacted cerumen	0.002	0.998	0.000
S27.3 Other injuries of lung	0.000	0.998	0.002
M20.3 Other deformity of hallux (acquired)	0.002	0.998	0.000
R26.0 Ataxic gait	0.000	0.998	0.002
S27 Injury of other and unspecified intrathoracic organs	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations