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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10179686
log Bayes Factor = 6.26048
Chromosome 2   position 135,214,570  (GRCh37) Explore rs10179686 on Ensembl!
Variant rs10179686 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.989 0.011 0.000
G90-G99 Other disorders of the nervous system
0.987 0.013 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.985 0.015 0.000
H90-H95 Other disorders of ear
0.984 0.016 0.000
G93 Other disorders of brain
0.976 0.024 0.000
Chapter XX External causes of morbidity and mortality
0.969 0.031 0.000
H65-H75 Diseases of middle ear and mastoid
0.960 0.040 0.000
H91 Other hearing loss
0.950 0.050 0.000
M70-M79 Other soft tissue disorders
0.949 0.051 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.947 0.053 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.941 0.059 0.000
R30-R39 Symptoms and signs involving the urinary system
0.937 0.063 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.936 0.064 0.000
H80-H83 Diseases of inner ear
0.931 0.069 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.928 0.072 0.000
H30-H36 Disorders of choroid and retina
0.922 0.078 0.000
G20-G26 Extrapyramidal and movement disorders
0.921 0.079 0.000
S00-S09 Injuries to the head
0.920 0.080 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.918 0.082 0.000
H91.9 Hearing loss, unspecified
0.918 0.082 0.000
S50-S59 Injuries to the elbow and forearm
0.918 0.082 0.000
H65 Nonsuppurative otitis media
0.915 0.085 0.000
G93.3 Postviral fatigue syndrome
0.913 0.087 0.000
R33 Retention of urine
0.913 0.087 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.910 0.090 0.000
T39.1 4-Aminophenol derivatives
0.907 0.093 0.000
S70-S79 Injuries to the hip and thigh
0.906 0.094 0.000
Chapter V Mental and behavioural disorders
0.901 0.099 0.000
T40.2 Other opioids
0.893 0.107 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.891 0.109 0.000
H81 Disorders of vestibular function
0.884 0.116 0.000
G93.9 Disorder of brain, unspecified
0.882 0.118 0.000
M75 Shoulder lesions
0.877 0.123 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.874 0.126 0.000
H02 Other disorders of eyelid
0.871 0.129 0.000
S52 Fracture of forearm
0.871 0.129 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.871 0.129 0.000
H90 Conductive and sensorineural hearing loss
0.863 0.137 0.000
H02.3 Blepharochalasis
0.862 0.138 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.862 0.138 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.857 0.143 0.000
H33 Retinal detachments and breaks
0.853 0.147 0.000
G91 Hydrocephalus
0.847 0.153 0.000
G20 Parkinson's disease
0.840 0.160 0.000
M20-M25 Other joint disorders
0.839 0.161 0.000
H81.1 Benign paroxysmal vertigo
0.838 0.162 0.000
F30-F39 Mood [affective] disorders
0.838 0.162 0.000
H65.3 Chronic mucoid otitis media
0.838 0.162 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.834 0.166 0.000
S80-S89 Injuries to the knee and lower leg
0.832 0.168 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.830 0.170 0.000
S00 Superficial injury of head
0.828 0.172 0.000
W00-W19 Falls
0.827 0.173 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.827 0.173 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.821 0.179 0.000
T93 Sequelae of injuries of lower limb
0.819 0.181 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.816 0.184 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.816 0.184 0.000
H53-H54 Visual disturbances and blindness
0.815 0.185 0.000
T66-T78 Other and unspecified effects of external causes
0.815 0.185 0.000
M40-M43 Deforming dorsopathies
0.814 0.186 0.000
M80-M85 Disorders of bone density and structure
0.813 0.187 0.000
M75.2 Bicipital tendinitis
0.811 0.189 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.811 0.189 0.000
T51 Toxic effect of alcohol
0.810 0.190 0.000
Chapter I Certain infectious and parasitic diseases
0.809 0.191 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.808 0.192 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.804 0.196 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.803 0.197 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.802 0.198 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.800 0.200 0.000
R32 Unspecified urinary incontinence
0.799 0.201 0.000
S52.5 Fracture of lower end of radius
0.798 0.202 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.796 0.204 0.000
M75.1 Rotator cuff syndrome
0.795 0.205 0.000
T36 Poisoning by systemic antibiotics
0.793 0.207 0.000
G93.8 Other specified disorders of brain
0.789 0.211 0.000
H33.2 Serous retinal detachment
0.789 0.211 0.000
R31 Unspecified haematuria
0.789 0.211 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.788 0.212 0.000
H21 Other disorders of iris and ciliary body
0.785 0.215 0.000
X60-X84 Intentional self-harm
0.783 0.217 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.782 0.218 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.781 0.219 0.000
F32 Depressive episode
0.771 0.229 0.000
W50-W64 Exposure to animate mechanical forces
0.771 0.229 0.000
G93.0 Cerebral cysts
0.771 0.229 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.768 0.232 0.000
T79-T79 Certain early complications of trauma
0.768 0.232 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.768 0.232 0.000
Y83.8 Other surgical procedures
0.768 0.232 0.000
H72 Perforation of tympanic membrane
0.766 0.234 0.000
H02.6 Xanthelasma of eyelid
0.765 0.235 0.000
H55-H59 Other disorders of eye and adnexa
0.764 0.236 0.000
H60-H62 Diseases of external ear
0.763 0.236 0.000
M15-M19 Arthrosis
0.763 0.237 0.000
M91-M94 Chondropathies
0.761 0.239 0.000
M20 Acquired deformities of fingers and toes
0.761 0.239 0.000
H33.0 Retinal detachment with retinal break
0.757 0.243 0.000
S71 Open wound of hip and thigh
0.755 0.245 0.000
M77 Other enthesopathies
0.753 0.247 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.752 0.247 0.000
M86-M90 Other osteopathies
0.752 0.248 0.000
R34 Anuria and oliguria
0.752 0.248 0.000
M75.3 Calcific tendinitis of shoulder
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.751 0.249 0.000
S06 Intracranial injury
0.751 0.249 0.000
F60-F69 Disorders of adult personality and behaviour
0.751 0.249 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.750 0.250 0.000
S60-S69 Injuries to the wrist and hand
0.749 0.251 0.000
T91 Sequelae of injuries of neck and trunk
0.747 0.252 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.747 0.253 0.000
H91.8 Other specified hearing loss
0.746 0.254 0.000
S52.50 Fracture of lower end of radius (closed)
0.746 0.254 0.000
H01 Other inflammation of eyelid
0.746 0.254 0.000
H35 Other retinal disorders
0.746 0.254 0.000
M65-M68 Disorders of synovium and tendon
0.746 0.254 0.000
H05 Disorders of orbit
0.745 0.255 0.000
T56 Toxic effect of metals
0.745 0.255 0.000
F99-F99 Unspecified mental disorder
0.744 0.256 0.000
M19 Other arthrosis
0.741 0.259 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.741 0.259 0.000
H80 Otosclerosis
0.739 0.261 0.000
G90 Disorders of autonomic nervous system
0.736 0.264 0.000
R39 Other symptoms and signs involving the urinary system
0.735 0.265 0.000
Chapter XXII Codes for special purposes
0.731 0.269 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.730 0.270 0.000
S72 Fracture of femur
0.729 0.271 0.000
H18 Other disorders of cornea
0.729 0.271 0.000
S52.0 Fracture of upper end of ulna
0.728 0.272 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.727 0.273 0.000
H74 Other disorders of middle ear and mastoid
0.727 0.273 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.726 0.273 0.000
G93.2 Benign intracranial hypertension
0.726 0.273 0.000
S70 Superficial injury of hip and thigh
0.726 0.274 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.725 0.275 0.000
M43 Other deforming dorsopathies
0.724 0.276 0.000
G70-G73 Diseases of myoneural junction and muscle
0.720 0.279 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.720 0.280 0.000
M24 Other specific joint derangements
0.720 0.280 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.719 0.281 0.000
G24 Dystonia
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G25 Other extrapyramidal and movement disorders
0.716 0.284 0.000
M19.9 Arthrosis, unspecified
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
H34 Retinal vascular occlusions
0.713 0.287 0.000
S02 Fracture of skull and facial bones
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.711 0.289 0.000
G93.6 Cerebral oedema
0.711 0.289 0.000
V10-V19 Pedal cyclist injured in transport accident
0.711 0.289 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.711 0.289 0.000
M23 Internal derangement of knee
0.709 0.291 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.708 0.292 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.708 0.292 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.708 0.292 0.000
G92 Toxic encephalopathy
0.708 0.292 0.000
M60-M63 Disorders of muscles
0.706 0.293 0.000
M00-M03 Infectious arthropathies
0.706 0.293 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.706 0.294 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.706 0.294 0.000
G95 Other diseases of spinal cord
0.704 0.296 0.000
M76 Enthesopathies of lower limb, excluding foot
0.703 0.296 0.000
T17 Foreign body in respiratory tract
0.703 0.297 0.000
H66 Suppurative and unspecified otitis media
0.702 0.298 0.000
G91.9 Hydrocephalus, unspecified
0.702 0.298 0.000
M20.5 Other deformities of toe(s) (acquired)
0.702 0.298 0.000
H65.2 Chronic serous otitis media
0.701 0.299 0.000
S00.9 Superficial injury of head, part unspecified
0.700 0.299 0.000
R87 Abnormal findings in specimens from female genital organs
0.700 0.300 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.700 0.300 0.000
G93.7 Reye's syndrome
0.699 0.300 0.000
G93.5 Compression of brain
0.699 0.300 0.000
H71 Cholesteatoma of middle ear
0.698 0.302 0.000
W19 Unspecified fall
0.697 0.303 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.697 0.303 0.000
M20.1 Hallux valgus (acquired)
0.696 0.304 0.000
H95.1 Other disorders following mastoidectomy
0.696 0.304 0.000
R20 Disturbances of skin sensation
0.696 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X20-X29 Contact with venomous animals and plants
0.695 0.305 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V40-V49 Car occupant injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.305 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.694 0.306 0.000
H93 Other disorders of ear, not elsewhere classified
0.693 0.307 0.000
T51.0 Ethanol
0.693 0.307 0.000
S80 Superficial injury of lower leg
0.692 0.308 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.692 0.308 0.000
T98 Sequelae of other and unspecified effects of external causes
0.691 0.309 0.000
H90.3 Sensorineural hearing loss, bilateral
0.690 0.310 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.690 0.310 0.000
G96 Other disorders of central nervous system
0.690 0.310 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.688 0.312 0.000
H70 Mastoiditis and related conditions
0.688 0.312 0.000
H69 Other disorders of Eustachian tube
0.688 0.312 0.000
H68 Eustachian salpingitis and obstruction
0.688 0.312 0.000
H67 Otitis media in diseases classified elsewhere
0.688 0.312 0.000
M05-M14 Inflammatory polyarthropathies
0.687 0.313 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.686 0.314 0.000
R47-R49 Symptoms and signs involving speech and voice
0.684 0.316 0.000
H10-H13 Disorders of conjunctiva
0.684 0.316 0.000
S09 Other and unspecified injuries of head
0.684 0.316 0.000
W06 Fall involving bed
0.683 0.317 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.682 0.318 0.000
T78 Adverse effects, not elsewhere classified
0.682 0.318 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.681 0.319 0.000
H91.3 Deaf mutism, not elsewhere classified
0.681 0.319 0.000
H91.2 Sudden idiopathic hearing loss
0.681 0.319 0.000
H91.1 Presbycusis
0.681 0.319 0.000
H91.0 Ototoxic hearing loss
0.681 0.319 0.000
G91.1 Obstructive hydrocephalus
0.681 0.319 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.681 0.319 0.000
G93.4 Encephalopathy, unspecified
0.680 0.319 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.679 0.321 0.000
B35-B49 Mycoses
0.679 0.321 0.000
H81.0 Meniere's disease
0.678 0.322 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.677 0.323 0.000
M79.1 Myalgia
0.677 0.323 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.675 0.325 0.000
Y83.6 Removal of other organ (partial) (total)
0.675 0.325 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.675 0.325 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.675 0.325 0.000
T39.4 Antirheumatics, not elsewhere classified
0.675 0.325 0.000
T39.2 Pyrazolone derivatives
0.675 0.325 0.000
R41.0 Disorientation, unspecified
0.675 0.325 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.674 0.326 0.000
M19.94 Arthrosis, unspecified (Hand)
0.674 0.326 0.000
A00-A09 Intestinal infectious diseases
0.674 0.326 0.000
H90.5 Sensorineural hearing loss, unspecified
0.673 0.327 0.000
M71 Other bursopathies
0.673 0.327 0.000
F33 Recurrent depressive disorder
0.673 0.327 0.000
H90.0 Conductive hearing loss, bilateral
0.672 0.328 0.000
R36 Urethral discharge
0.672 0.328 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.671 0.329 0.000
T40.8 Lysergide [LSD]
0.671 0.329 0.000
T40.7 Cannabis (derivatives)
0.671 0.329 0.000
T40.6 Other and unspecified narcotics
0.671 0.329 0.000
T40.5 Cocaine
0.671 0.329 0.000
T40.4 Other synthetic narcotics
0.671 0.329 0.000
T40.3 Methadone
0.671 0.329 0.000
T40.1 Heroin
0.671 0.329 0.000
T40.0 Opium
0.671 0.329 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.671 0.329 0.000
T51.9 Alcohol, unspecified
0.670 0.329 0.000
S00.0 Superficial injury of scalp
0.670 0.330 0.000
T90 Sequelae of injuries of head
0.669 0.331 0.000
S79 Other and unspecified injuries of hip and thigh
0.668 0.332 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.668 0.332 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.666 0.334 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.666 0.334 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.665 0.335 0.000
H92 Otalgia and effusion of ear
0.664 0.336 0.000
Q50-Q56 Congenital malformations of genital organs
0.662 0.338 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.661 0.339 0.000
H31 Other disorders of choroid
0.661 0.339 0.000
H30 Chorioretinal inflammation
0.661 0.339 0.000
M75.9 Shoulder lesion, unspecified
0.661 0.339 0.000
H90.2 Conductive hearing loss, unspecified
0.661 0.339 0.000
G23 Other degenerative diseases of basal ganglia
0.661 0.339 0.000
G21 Secondary Parkinsonism
0.661 0.339 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.661 0.339 0.000
G22 Parkinsonism in diseases classified elsewhere
0.661 0.339 0.000
S08 Traumatic amputation of part of head
0.659 0.340 0.000
S07 Crushing injury of head
0.659 0.340 0.000
S05 Injury of eye and orbit
0.659 0.340 0.000
S04 Injury of cranial nerves
0.659 0.340 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.659 0.340 0.000
H81.2 Vestibular neuronitis
0.659 0.341 0.000
H00 Hordeolum and chalazion
0.659 0.341 0.000
T95 Sequelae of burns, corrosions and frostbite
0.658 0.342 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.658 0.342 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.658 0.342 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.658 0.342 0.000
S59 Other and unspecified injuries of forearm
0.658 0.342 0.000
S58 Traumatic amputation of forearm
0.658 0.342 0.000
S57 Crushing injury of forearm
0.658 0.342 0.000
S56 Injury of muscle and tendon at forearm level
0.658 0.342 0.000
S55 Injury of blood vessels at forearm level
0.658 0.342 0.000
S54 Injury of nerves at forearm level
0.658 0.342 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.658 0.342 0.000
S50 Superficial injury of forearm
0.658 0.342 0.000
H73 Other disorders of tympanic membrane
0.657 0.343 0.000
H65.1 Other acute nonsuppurative otitis media
0.656 0.344 0.000
H65.0 Acute serous otitis media
0.656 0.344 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.654 0.346 0.000
R20.2 Paraesthesia of skin
0.654 0.346 0.000
W20-W49 Exposure to inanimate mechanical forces
0.653 0.347 0.000
S52.6 Fracture of lower end of both ulna and radius
0.653 0.347 0.000
T65 Toxic effect of other and unspecified substances
0.653 0.347 0.000
T63 Toxic effect of contact with venomous animals
0.653 0.347 0.000
T62 Toxic effect of other noxious substances eaten as food
0.653 0.347 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.653 0.347 0.000
T60 Toxic effect of pesticides
0.653 0.347 0.000
T59 Toxic effect of other gases, fumes and vapours
0.653 0.347 0.000
T57 Toxic effect of other inorganic substances
0.653 0.347 0.000
T54 Toxic effect of corrosive substances
0.653 0.347 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.653 0.347 0.000
T52 Toxic effect of organic solvents
0.653 0.347 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.653 0.347 0.000
T58 Toxic effect of carbon monoxide
0.653 0.347 0.000
T55 Toxic effect of soaps and detergents
0.653 0.347 0.000
M43.1 Spondylolisthesis
0.653 0.347 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.652 0.348 0.000
Q60-Q64 Congenital malformations of the urinary system
0.651 0.349 0.000
M79.6 Pain in limb
0.650 0.350 0.000
S52.1 Fracture of upper end of radius
0.650 0.350 0.000
S78 Traumatic amputation of hip and thigh
0.649 0.350 0.000
S77 Crushing injury of hip and thigh
0.649 0.350 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.649 0.350 0.000
S75 Injury of blood vessels at hip and thigh level
0.649 0.350 0.000
S74 Injury of nerves at hip and thigh level
0.649 0.350 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.649 0.350 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.649 0.351 0.000
S71.1 Open wound of thigh
0.648 0.352 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.647 0.353 0.000
H53 Visual disturbances
0.647 0.353 0.000
T36.0 Penicillins
0.646 0.353 0.000
T93.2 Sequelae of other fractures of lower limb
0.646 0.354 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.646 0.354 0.000
F70-F79 Mental retardation
0.646 0.354 0.000
B15-B19 Viral hepatitis
0.646 0.354 0.000
S89 Other and unspecified injuries of lower leg
0.645 0.355 0.000
H65.4 Other chronic nonsuppurative otitis media
0.645 0.355 0.000
H52 Disorders of refraction and accommodation
0.645 0.355 0.000
H21.8 Other specified disorders of iris and ciliary body
0.644 0.355 0.000
M81 Osteoporosis without pathological fracture
0.644 0.356 0.000
H54 Blindness and low vision
0.643 0.357 0.000
F60 Specific personality disorders
0.643 0.357 0.000
M23.8 Other internal derangements of knee
0.641 0.359 0.000
H35.3 Degeneration of macula and posterior pole
0.640 0.360 0.000
T92 Sequelae of injuries of upper limb
0.639 0.361 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.638 0.361 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.638 0.361 0.000
H17 Corneal scars and opacities
0.638 0.361 0.000
H16 Keratitis
0.638 0.361 0.000
H15 Disorders of sclera
0.638 0.361 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.638 0.362 0.000
M50-M54 Other dorsopathies
0.638 0.362 0.000
Y85 Sequelae of transport accidents
0.637 0.362 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.635 0.364 0.000
V20-V29 Motorcycle rider injured in transport accident
0.635 0.365 0.000
H50 Other strabismus
0.634 0.366 0.000
H81.9 Disorder of vestibular function, unspecified
0.634 0.366 0.000
H81.8 Other disorders of vestibular function
0.634 0.366 0.000
H81.4 Vertigo of central origin
0.634 0.366 0.000
H81.3 Other peripheral vertigo
0.634 0.366 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.634 0.366 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.632 0.368 0.000
H61 Other disorders of external ear
0.632 0.368 0.000
F99 Mental disorder, not otherwise specified
0.631 0.369 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.631 0.369 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.631 0.369 0.000
T39.0 Salicylates
0.630 0.370 0.000
S00.7 Multiple superficial injuries of head
0.629 0.370 0.000
W55 Bitten or struck by other mammals
0.629 0.371 0.000
M72 Fibroblastic disorders
0.629 0.371 0.000
M75.8 Other shoulder lesions
0.629 0.371 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.628 0.372 0.000
R87.6 Abnormal cytological findings
0.628 0.372 0.000
H20 Iridocyclitis
0.627 0.373 0.000
S52.8 Fracture of other parts of forearm
0.627 0.373 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.626 0.373 0.000
T56.8 Other metals
0.626 0.374 0.000
M21 Other acquired deformities of limbs
0.626 0.374 0.000
S52.00 Fracture of upper end of ulna (closed)
0.626 0.374 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.625 0.375 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.625 0.375 0.000
H02.2 Lagophthalmos
0.625 0.375 0.000
S52.9 Fracture of forearm, part unspecified
0.625 0.375 0.000
S52.7 Multiple fractures of forearm
0.625 0.375 0.000
S52.4 Fracture of shafts of both ulna and radius
0.625 0.375 0.000
S52.3 Fracture of shaft of radius
0.625 0.375 0.000
S52.2 Fracture of shaft of ulna
0.625 0.375 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.625 0.375 0.000
Q80-Q89 Other congenital malformations
0.625 0.375 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.625 0.375 0.000
Q35-Q37 Cleft lip and cleft palate
0.625 0.375 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.625 0.375 0.000
X58 Exposure to other specified factors
0.623 0.377 0.000
S82 Fracture of lower leg, including ankle
0.623 0.377 0.000
H33.5 Other retinal detachments
0.623 0.377 0.000
W19.9 Unspecified place
0.623 0.377 0.000
M84 Disorders of continuity of bone
0.622 0.378 0.000
S20-S29 Injuries to the thorax
0.619 0.381 0.000
G40-G47 Episodic and paroxysmal disorders
0.619 0.381 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.619 0.381 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.619 0.381 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.619 0.381 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.619 0.381 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.619 0.381 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.619 0.381 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.618 0.382 0.000
T17.2 Foreign body in pharynx
0.618 0.382 0.000
Q00-Q07 Congenital malformations of the nervous system
0.616 0.384 0.000
H05.0 Acute inflammation of orbit
0.614 0.386 0.000
Chapter X Diseases of the respiratory system
0.613 0.387 0.000
S00.1 Contusion of eyelid and periocular area
0.613 0.387 0.000
M79.7 Fibromyalgia
0.613 0.387 0.000
M77.9 Enthesopathy, unspecified
0.612 0.387 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.612 0.388 0.000
H01.8 Other specified inflammation of eyelid
0.612 0.388 0.000
H33.4 Traction detachment of retina
0.612 0.388 0.000
H33.1 Retinoschisis and retinal cysts
0.612 0.388 0.000
F80-F89 Disorders of psychological development
0.612 0.388 0.000
M89 Other disorders of bone
0.611 0.389 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.611 0.389 0.000
M19.0 Primary arthrosis of other joints
0.610 0.390 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.610 0.390 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.610 0.390 0.000
S06.2 Diffuse brain injury
0.608 0.391 0.000
F31 Bipolar affective disorder
0.608 0.392 0.000
G91.8 Other hydrocephalus
0.607 0.393 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.607 0.393 0.000
G91.2 Normal-pressure hydrocephalus
0.607 0.393 0.000
G91.0 Communicating hydrocephalus
0.607 0.393 0.000
J40-J47 Chronic lower respiratory diseases
0.606 0.394 0.000
T43.2 Other and unspecified antidepressants
0.606 0.394 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.605 0.395 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.604 0.396 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.603 0.397 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.603 0.397 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.602 0.398 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.602 0.398 0.000
S40-S49 Injuries to the shoulder and upper arm
0.602 0.398 0.000
H80.9 Otosclerosis, unspecified
0.602 0.398 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.601 0.399 0.000
M34 Systemic sclerosis
0.601 0.399 0.000
M33 Dermatopolymyositis
0.601 0.399 0.000
M32 Systemic lupus erythematosus
0.601 0.399 0.000
M30 Polyarteritis nodosa and related conditions
0.601 0.399 0.000
F38 Other mood [affective] disorders
0.601 0.399 0.000
F34 Persistent mood [affective] disorders
0.601 0.399 0.000
F30 Manic episode
0.601 0.399 0.000
F39 Unspecified mood [affective] disorder
0.601 0.399 0.000
S06.5 Traumatic subdural haemorrhage
0.600 0.400 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.600 0.400 0.000
M85 Other disorders of bone density and structure
0.600 0.400 0.000
G61 Inflammatory polyneuropathy
0.600 0.400 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.598 0.402 0.000
H02.9 Disorder of eyelid, unspecified
0.598 0.402 0.000
H43-H45 Disorders of vitreous body and globe
0.598 0.402 0.000
S70.0 Contusion of hip
0.597 0.403 0.000
T42.4 Benzodiazepines
0.597 0.403 0.000
S88 Traumatic amputation of lower leg
0.597 0.403 0.000
S87 Crushing injury of lower leg
0.597 0.403 0.000
S86 Injury of muscle and tendon at lower leg level
0.597 0.403 0.000
S85 Injury of blood vessels at lower leg level
0.597 0.403 0.000
S84 Injury of nerves at lower leg level
0.597 0.403 0.000
J43 Emphysema
0.596 0.404 0.000
R41.3 Other amnesia
0.596 0.404 0.000
M80 Osteoporosis with pathological fracture
0.596 0.404 0.000
H55 Nystagmus and other irregular eye movements
0.596 0.404 0.000
M67 Other disorders of synovium and tendon
0.595 0.405 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.595 0.405 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.595 0.405 0.000
T46.7 Peripheral vasodilators
0.595 0.405 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.595 0.405 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.595 0.405 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.595 0.405 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.595 0.405 0.000
T46.1 Calcium-channel blockers
0.595 0.405 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.595 0.405 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.595 0.405 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.594 0.406 0.000
S00.5 Superficial injury of lip and oral cavity
0.594 0.406 0.000
S00.4 Superficial injury of ear
0.594 0.406 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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