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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10185178
log Bayes Factor = 4.19488
Chromosome 2   position 171,356,274  (GRCh37) Explore rs10185178 on Ensembl!
Variant rs10185178 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.000 0.000 1.000
Chapter XXI Factors influencing health status and contact with health services
0.000 0.000 1.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.000 0.004 0.996
Chapter II Neoplasms
0.000 0.020 0.980
Z40-Z54 Persons encountering health services for specific procedures and health care
0.000 0.020 0.980
Chapter XI Diseases of the digestive system
0.000 0.035 0.965
Z90 Acquired absence of organs, not elsewhere classified
0.000 0.042 0.958
K55-K64 Other diseases of intestines
0.000 0.049 0.951
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.072 0.928
Z51 Other medical care
0.000 0.073 0.927
Chapter XIV Diseases of the genitourinary system
0.000 0.084 0.916
K62 Other diseases of anus and rectum
0.000 0.089 0.911
Z86 Personal history of certain other diseases
0.000 0.100 0.900
Chapter IX Diseases of the circulatory system
0.000 0.100 0.900
Z92 Personal history of medical treatment
0.000 0.103 0.897
Chapter X Diseases of the respiratory system
0.000 0.106 0.894
K63 Other diseases of intestine
0.000 0.108 0.892
Z90.7 Acquired absence of genital organ(s)
0.000 0.120 0.880
N30-N39 Other diseases of urinary system
0.000 0.121 0.879
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.127 0.873
K62.5 Haemorrhage of anus and rectum
0.000 0.133 0.867
Z00-Z13 Persons encountering health services for examination and investigation
0.000 0.137 0.863
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.139 0.861
Z85 Personal history of malignant neoplasm
0.000 0.144 0.855
Z45 Adjustment and management of implanted device
0.000 0.153 0.847
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.000 0.155 0.845
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.155 0.845
K63.5 Polyp of colon
0.000 0.156 0.844
Chapter I Certain infectious and parasitic diseases
0.000 0.157 0.843
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.158 0.842
Z51.5 Palliative care
0.000 0.163 0.837
Chapter VI Diseases of the nervous system
0.000 0.163 0.837
Chapter V Mental and behavioural disorders
0.000 0.164 0.836
C79 Secondary malignant neoplasm of other sites
0.000 0.189 0.811
Z86.4 Personal history of psychoactive substance abuse
0.000 0.191 0.809
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.195 0.805
C15-C26 Malignant neoplasms of digestive organs
0.000 0.197 0.803
N39 Other disorders of urinary system
0.000 0.197 0.803
Z93 Artificial opening status
0.000 0.198 0.802
I20-I25 Ischaemic heart diseases
0.000 0.208 0.792
I30-I52 Other forms of heart disease
0.000 0.210 0.790
Z92.2 Personal history of long-term (current) use of other medicaments
0.000 0.212 0.788
Chapter VIII Diseases of the ear and mastoid process
0.000 0.218 0.782
Z80 Family history of malignant neoplasm
0.000 0.221 0.778
Z47 Other orthopaedic follow-up care
0.000 0.230 0.770
Z84 Family history of other conditions
0.000 0.232 0.768
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.000 0.236 0.764
Z83 Family history of other specific disorders
0.000 0.236 0.763
M70-M79 Other soft tissue disorders
0.000 0.243 0.757
Chapter VII Diseases of the eye and adnexa
0.000 0.244 0.756
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.245 0.755
Z90.4 Acquired absence of other parts of digestive tract
0.000 0.245 0.755
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.246 0.754
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.246 0.754
Z41 Procedures for purposes other than remedying health state
0.000 0.247 0.753
Z90.5 Acquired absence of kidney
0.000 0.247 0.753
Z51.1 Chemotherapy session for neoplasm
0.000 0.247 0.753
Z89 Acquired absence of limb
0.000 0.250 0.750
M50-M54 Other dorsopathies
0.000 0.250 0.750
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.251 0.749
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.000 0.251 0.749
J20-J22 Other acute lower respiratory infections
0.000 0.252 0.747
N70-N77 Inflammatory diseases of female pelvic organs
0.000 0.253 0.747
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.254 0.746
K60 Fissure and fistula of anal and rectal regions
0.000 0.255 0.745
Z42 Follow-up care involving plastic surgery
0.000 0.259 0.740
Z90.1 Acquired absence of breast(s)
0.000 0.260 0.739
N32 Other disorders of bladder
0.000 0.263 0.737
Z50 Care involving use of rehabilitation procedures
0.000 0.265 0.735
C78.7 Secondary malignant neoplasm of liver
0.000 0.266 0.734
Z40 Prophylactic surgery
0.000 0.267 0.733
Z48 Other surgical follow-up care
0.000 0.267 0.733
I60-I69 Cerebrovascular diseases
0.000 0.268 0.732
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.268 0.732
Z51.3 Blood transfusion without reported diagnosis
0.000 0.270 0.730
N39.0 Urinary tract infection, site not specified
0.000 0.272 0.728
C64-C68 Malignant neoplasms of urinary tract
0.000 0.272 0.728
C50-C50 Malignant neoplasm of breast
0.000 0.275 0.725
Z90.6 Acquired absence of other parts of urinary tract
0.000 0.276 0.724
Z86.0 Personal history of other neoplasms
0.000 0.276 0.724
Z13 Special screening examination for other diseases and disorders
0.000 0.276 0.724
N10-N16 Renal tubulo-interstitial diseases
0.000 0.277 0.723
D00-D09 In situ neoplasms
0.000 0.277 0.723
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.000 0.277 0.723
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.278 0.722
C51-C58 Malignant neoplasms of female genital organs
0.000 0.281 0.719
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
Z85.5 Personal history of malignant neoplasm of urinary tract
0.000 0.284 0.716
A00-A09 Intestinal infectious diseases
0.000 0.284 0.716
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.285 0.715
Z70-Z76 Persons encountering health services in other circumstances
0.000 0.285 0.715
J30-J39 Other diseases of upper respiratory tract
0.000 0.288 0.712
Z90.2 Acquired absence of lung [part of]
0.000 0.289 0.711
K62.8 Other specified diseases of anus and rectum
0.000 0.290 0.710
Z81 Family history of mental and behavioural disorders
0.000 0.291 0.708
Z86.7 Personal history of diseases of the circulatory system
0.000 0.292 0.708
Z94 Transplanted organ and tissue status
0.000 0.293 0.706
R50-R69 General symptoms and signs
0.000 0.294 0.706
G50-G59 Nerve, nerve root and plexus disorders
0.000 0.295 0.705
I25 Chronic ischaemic heart disease
0.000 0.295 0.705
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.000 0.296 0.704
N35 Urethral stricture
0.000 0.297 0.703
K63.3 Ulcer of intestine
0.000 0.298 0.702
C80 Malignant neoplasm without specification of site
0.000 0.298 0.702
Z51.0 Radiotherapy session
0.000 0.300 0.700
Chapter XXII Codes for special purposes
0.000 0.300 0.700
Z90.8 Acquired absence of other organs
0.000 0.301 0.699
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.301 0.699
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.301 0.699
Z92.4 Personal history of major surgery, not elsewhere classified
0.000 0.302 0.698
J09-J18 Influenza and pneumonia
0.000 0.302 0.698
Z44 Fitting and adjustment of external prosthetic device
0.000 0.302 0.697
C44 Other malignant neoplasms of skin
0.000 0.304 0.695
K35-K38 Diseases of appendix
0.000 0.305 0.695
K56 Paralytic ileus and intestinal obstruction without hernia
0.000 0.305 0.695
Z54 Convalescence
0.000 0.305 0.694
Z90.3 Acquired absence of part of stomach
0.000 0.307 0.693
I10-I15 Hypertensive diseases
0.000 0.307 0.693
Z53 Persons encountering health services for specifie procedures, not carried out
0.000 0.307 0.693
Z45.2 Adjustment and management of vascular access device
0.000 0.308 0.692
K62.1 Rectal polyp
0.000 0.309 0.691
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.310 0.690
Z51.2 Other chemotherapy
0.000 0.311 0.689
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.311 0.689
C43 Malignant melanoma of skin
0.000 0.312 0.688
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.312 0.688
Z52 Donors of organs and tissues
0.000 0.313 0.687
Z92.8 Personal history of other medical treatment
0.000 0.314 0.686
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.314 0.686
N00-N08 Glomerular diseases
0.000 0.316 0.684
Z49 Care involving dialysis
0.000 0.316 0.684
I44 Atrioventricular and left bundle-branch block
0.000 0.316 0.684
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.000 0.317 0.683
Z98 Other postsurgical states
0.000 0.317 0.683
K62.9 Disease of anus and rectum, unspecified
0.000 0.317 0.683
K64 Haemorrhoids and perianal venous thrombosis
0.000 0.318 0.682
J95-J99 Other diseases of the respiratory system
0.000 0.320 0.680
Z43 Attention to artificial openings
0.000 0.320 0.679
M80-M85 Disorders of bone density and structure
0.000 0.321 0.679
D70 Agranulocytosis
0.000 0.321 0.679
Z45.0 Adjustment and management of cardiac pacemaker
0.000 0.324 0.676
D10-D36 Benign neoplasms
0.000 0.325 0.675
Z90.0 Acquired absence of part of head and neck
0.000 0.325 0.675
C78.0 Secondary malignant neoplasm of lung
0.000 0.326 0.674
K58 Irritable bowel syndrome
0.000 0.327 0.673
N36 Other disorders of urethra
0.000 0.327 0.673
K62.3 Rectal prolapse
0.000 0.327 0.673
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.327 0.672
K65-K67 Diseases of peritoneum
0.000 0.328 0.672
F30-F39 Mood [affective] disorders
0.000 0.331 0.669
J90-J94 Other diseases of pleura
0.000 0.332 0.668
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.000 0.332 0.668
M45-M49 Spondylopathies
0.000 0.333 0.667
Z97 Presence of other devices
0.000 0.333 0.667
Z46 Fitting and adjustment of other devices
0.000 0.333 0.666
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.000 0.334 0.666
K40-K46 Hernia
0.000 0.334 0.665
G90-G99 Other disorders of the nervous system
0.000 0.336 0.664
Z51.6 Desensitisation to allergens
0.000 0.337 0.663
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.338 0.662
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.338 0.662
Z51.8 Other specified medical care
0.000 0.338 0.661
Z51.4 Preparatory care for treatment, not elsewhere classified
0.000 0.340 0.660
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.340 0.660
D80-D89 Certain disorders involving the immune mechanism
0.000 0.340 0.660
K61 Abscess of anal and rectal regions
0.000 0.340 0.660
Z08 Follow-up examination after treatment for malignant neoplasm
0.000 0.340 0.660
C79.8 Secondary malignant neoplasm of other specified sites
0.000 0.341 0.659
Z99.3 Dependence on wheelchair
0.000 0.341 0.659
Z51.9 Medical care, unspecified
0.000 0.341 0.659
K63.8 Other specified diseases of intestine
0.000 0.341 0.659
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.000 0.341 0.659
Z92.0 Personal history of contraception
0.000 0.341 0.658
N17-N19 Renal failure
0.000 0.342 0.658
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.342 0.658
Z04 Examination and observation for other reasons
0.000 0.342 0.658
K55 Vascular disorders of intestine
0.000 0.343 0.657
K57 Diverticular disease of intestine
0.000 0.343 0.657
Z92.3 Personal history of irradiation
0.000 0.345 0.655
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.345 0.655
K62.6 Ulcer of anus and rectum
0.000 0.345 0.655
M54 Dorsalgia
0.000 0.345 0.655
J00-J06 Acute upper respiratory infections
0.000 0.345 0.654
R53 Malaise and fatigue
0.000 0.347 0.653
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.000 0.347 0.653
M86-M90 Other osteopathies
0.000 0.347 0.653
D50-D53 Nutritional anaemias
0.000 0.347 0.653
N99-N99 Other disorders of the genitourinary system
0.000 0.348 0.651
Z45.8 Adjustment and management of other implanted devices
0.000 0.348 0.651
Z91 Personal history of risk-factors, not elsewhere classified
0.000 0.350 0.650
C18 Malignant neoplasm of colon
0.000 0.350 0.650
K62.2 Anal prolapse
0.000 0.350 0.649
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.000 0.351 0.649
M60-M63 Disorders of muscles
0.000 0.351 0.649
Z86.5 Personal history of other mental and behavioural disorders
0.000 0.352 0.648
C78.4 Secondary malignant neoplasm of small intestine
0.000 0.353 0.647
J22 Unspecified acute lower respiratory infection
0.000 0.354 0.646
K63.1 Perforation of intestine (nontraumatic)
0.000 0.355 0.645
I00-I02 Acute rheumatic fever
0.000 0.356 0.644
Z02 Examination and encounter for administrative purposes
0.000 0.357 0.643
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.357 0.643
Z92.9 Personal history of medical treatment, unspecified
0.000 0.357 0.643
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.357 0.643
Z92.5 Personal history of rehabilitation measures
0.000 0.357 0.643
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.000 0.357 0.642
N34 Urethritis and urethral syndrome
0.000 0.358 0.642
R07 Pain in throat and chest
0.000 0.358 0.642
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.359 0.641
I47 Paroxysmal tachycardia
0.000 0.360 0.640
Z12 Special screening examination for neoplasms
0.000 0.361 0.639
N25-N29 Other disorders of kidney and ureter
0.000 0.361 0.639
Z80.0 Family history of malignant neoplasm of digestive organs
0.000 0.361 0.639
Z95.0 Presence of cardiac pacemaker
0.000 0.361 0.639
M05-M14 Inflammatory polyarthropathies
0.000 0.362 0.638
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.362 0.638
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.362 0.637
K63.4 Enteroptosis
0.000 0.363 0.637
K62.4 Stenosis of anus and rectum
0.000 0.363 0.637
N39.3 Stress incontinence
0.000 0.363 0.637
Z85.3 Personal history of malignant neoplasm of breast
0.000 0.363 0.637
K50-K52 Noninfective enteritis and colitis
0.000 0.363 0.637
H65-H75 Diseases of middle ear and mastoid
0.000 0.364 0.636
K63.0 Abscess of intestine
0.000 0.364 0.636
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.365 0.635
K62.0 Anal polyp
0.000 0.365 0.635
K62.7 Radiation proctitis
0.000 0.365 0.635
Z92.6 Personal history of chemotherapy for neoplastic disease
0.000 0.366 0.634
H25-H28 Disorders of lens
0.000 0.366 0.634
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.368 0.632
Z85.4 Personal history of malignant neoplasm of genital organs
0.000 0.368 0.632
M65-M68 Disorders of synovium and tendon
0.000 0.368 0.632
N37 Urethral disorders in diseases classified elsewhere
0.000 0.370 0.630
N33 Bladder disorders in diseases classified elsewhere
0.000 0.370 0.630
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.370 0.630
B35-B49 Mycoses
0.000 0.371 0.629
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.372 0.628
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.372 0.627
N32.8 Other specified disorders of bladder
0.000 0.374 0.626
K63.2 Fistula of intestine
0.000 0.374 0.626
J60-J70 Lung diseases due to external agents
0.000 0.376 0.624
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.376 0.624
K90-K93 Other diseases of the digestive system
0.000 0.376 0.624
C78.2 Secondary malignant neoplasm of pleura
0.000 0.377 0.623
Z92.1 Personal history of long-term (current) use of anticoagulants
0.000 0.377 0.623
M91-M94 Chondropathies
0.000 0.377 0.623
C60-C63 Malignant neoplasms of male genital organs
0.000 0.379 0.621
Z10 Routine general health check-up of defined subpopulation
0.000 0.381 0.619
B99-B99 Other infectious diseases
0.000 0.381 0.619
M00-M03 Infectious arthropathies
0.000 0.381 0.618
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.381 0.618
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.000 0.382 0.618
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.382 0.618
Z93.3 Colostomy status
0.000 0.382 0.618
B25-B34 Other viral diseases
0.000 0.383 0.617
M40-M43 Deforming dorsopathies
0.000 0.383 0.617
N30 Cystitis
0.000 0.385 0.615
A30-A49 Other bacterial diseases
0.000 0.386 0.614
I46 Cardiac arrest
0.000 0.386 0.613
Z85.0 Personal history of malignant neoplasm of digestive organs
0.000 0.387 0.613
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.000 0.387 0.613
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.000 0.387 0.613
R47-R49 Symptoms and signs involving speech and voice
0.000 0.387 0.613
F60-F69 Disorders of adult personality and behaviour
0.000 0.388 0.612
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.388 0.612
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.388 0.612
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.389 0.611
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.000 0.389 0.611
A80-A89 Viral infections of the central nervous system
0.000 0.389 0.610
I42 Cardiomyopathy
0.000 0.390 0.610
N60-N64 Disorders of breast
0.000 0.391 0.609
D55-D59 Haemolytic anaemias
0.000 0.391 0.609
R30-R39 Symptoms and signs involving the urinary system
0.000 0.392 0.608
Z11 Special screening examination for infectious and parasitic diseases
0.000 0.392 0.608
Z85.9 Personal history of malignant neoplasm, unspecified
0.000 0.393 0.607
Z45.9 Adjustment and management of unspecified implanted device
0.000 0.393 0.606
K59 Other functional intestinal disorders
0.000 0.394 0.606
R95-R99 Ill-defined and unknown causes of mortality
0.000 0.394 0.606
Z45.3 Adjustment and management of implanted hearing device
0.000 0.394 0.606
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.000 0.395 0.605
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.395 0.604
A75-A79 Rickettsioses
0.000 0.395 0.604
A70-A74 Other diseases caused by chlamydiae
0.000 0.395 0.604
I21 Acute myocardial infarction
0.000 0.396 0.604
A20-A28 Certain zoonotic bacterial diseases
0.000 0.396 0.604
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.396 0.604
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.396 0.603
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.000 0.397 0.603
C17 Malignant neoplasm of small intestine
0.000 0.397 0.603
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.397 0.603
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.000 0.397 0.603
A65-A69 Other spirochaetal diseases
0.000 0.397 0.603
Z99.2 Dependence on renal dialysis
0.000 0.398 0.602
I05-I09 Chronic rheumatic heart diseases
0.000 0.398 0.602
A15-A19 Tuberculosis
0.000 0.399 0.601
B50-B64 Protozoal diseases
0.000 0.399 0.601
B65-B83 Helminthiases
0.000 0.399 0.601
J40-J47 Chronic lower respiratory diseases
0.000 0.399 0.601
C78.1 Secondary malignant neoplasm of mediastinum
0.000 0.400 0.600
C79.6 Secondary malignant neoplasm of ovary
0.000 0.400 0.600
B95-B98 Bacterial, viral and other infectious agents
0.000 0.400 0.599
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.401 0.599
F70-F79 Mental retardation
0.000 0.401 0.599
Z13.9 Special screening examination, unspecified
0.000 0.402 0.598
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.000 0.402 0.598
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.402 0.598
I20 Angina pectoris
0.000 0.402 0.598
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.000 0.402 0.597
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.000 0.403 0.597
G20-G26 Extrapyramidal and movement disorders
0.000 0.403 0.597
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.000 0.404 0.596
Z45.1 Adjustment and management of infusion pump
0.000 0.404 0.596
C79.2 Secondary malignant neoplasm of skin
0.000 0.404 0.596
Z93.8 Other artificial opening status
0.000 0.404 0.596
J34 Other disorders of nose and nasal sinuses
0.000 0.404 0.596
I36 Nonrheumatic tricuspid valve disorders
0.000 0.404 0.596
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.000 0.405 0.595
K63.9 Disease of intestine, unspecified
0.000 0.406 0.594
Z85.6 Personal history of leukaemia
0.000 0.406 0.594
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.407 0.593
C79.9 Secondary malignant neoplasm, unspecified site
0.000 0.407 0.593
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.000 0.407 0.592
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.000 0.407 0.592
F99-F99 Unspecified mental disorder
0.000 0.408 0.592
Chapter XX External causes of morbidity and mortality
0.000 0.408 0.592
Z93.4 Other artificial openings of gastro-intestinal tract status
0.000 0.408 0.591
F80-F89 Disorders of psychological development
0.000 0.409 0.591
Z80.8 Family history of malignant neoplasm of other organs or systems
0.000 0.409 0.591
Z83.5 Family history of eye and ear disorders
0.000 0.409 0.590
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.000 0.410 0.590
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.000 0.410 0.590
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.411 0.589
Z93.5 Cystostomy status
0.000 0.411 0.589
B15-B19 Viral hepatitis
0.000 0.411 0.589
Z93.2 Ileostomy status
0.000 0.412 0.588
Z93.0 Tracheostomy status
0.000 0.412 0.588
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.413 0.587
K14 Diseases of tongue
0.000 0.413 0.587
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.413 0.587
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.000 0.414 0.586
K22 Other diseases of oesophagus
0.000 0.414 0.586
C21 Malignant neoplasm of anus and anal canal
0.000 0.415 0.585
G70-G73 Diseases of myoneural junction and muscle
0.000 0.416 0.584
G30-G32 Other degenerative diseases of the nervous system
0.000 0.416 0.584
N39.4 Other specified urinary incontinence
0.000 0.416 0.584
Z50.1 Other physical therapy
0.000 0.416 0.584
Z99.1 Dependence on respirator
0.000 0.417 0.583
Z60 Problems related to social environment
0.000 0.417 0.583
I63 Cerebral infarction
0.000 0.417 0.583
K60.3 Anal fistula
0.000 0.418 0.582
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.000 0.418 0.582
H30-H36 Disorders of choroid and retina
0.000 0.419 0.581
Z47.8 Other specified orthopaedic follow-up care
0.000 0.419 0.581
I69 Sequelae of cerebrovascular disease
0.000 0.419 0.581
C25 Malignant neoplasm of pancreas
0.000 0.420 0.580
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.421 0.579
N35.9 Urethral stricture, unspecified
0.000 0.421 0.579
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.421 0.579
Z93.6 Other artificial openings of urinary tract status
0.000 0.422 0.578
I25.2 Old myocardial infarction
0.000 0.422 0.578
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.423 0.577
Z99.4 Dependence on artificial heart
0.000 0.423 0.577
Z99.0 Dependence on aspirator
0.000 0.423 0.577
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.423 0.577
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.424 0.576
I31 Other diseases of pericardium
0.000 0.424 0.576
G56 Mononeuropathies of upper limb
0.000 0.424 0.576
N39.2 Orthostatic proteinuria, unspecified
0.000 0.424 0.575
I10 Essential (primary) hypertension
0.000 0.425 0.575
Z88.6 Personal history of allergy to analgesic agent
0.000 0.425 0.575
Z03 Medical observation and evaluation for suspected diseases and conditions
0.000 0.425 0.575
Z56 Problems related to employment and unemployment
0.000 0.425 0.574
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.426 0.574
N39.8 Other specified disorders of urinary system
0.000 0.426 0.574
N39.1 Persistent proteinuria, unspecified
0.000 0.426 0.574
Z93.9 Artificial opening status, unspecified
0.000 0.427 0.573
C23 Malignant neoplasm of gallbladder
0.000 0.427 0.573
M79.6 Pain in limb
0.000 0.427 0.573
Z84.0 Family history of diseases of the skin and subcutaneous tissue
0.000 0.428 0.572
Z84.1 Family history of disorders of the kidney and ureter
0.000 0.428 0.572
Z84.2 Family history of other diseases of the genito-urinary system
0.000 0.428 0.572
C44.7 Skin of lower limb, including hip
0.000 0.428 0.572
K13 Other diseases of lip and oral mucosa
0.000 0.429 0.571
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.429 0.570
N20-N23 Urolithiasis
0.000 0.430 0.570
C15 Malignant neoplasm of oesophagus
0.000 0.430 0.570
R07.2 Precordial pain
0.000 0.431 0.569
N39.9 Disorder of urinary system, unspecified
0.000 0.432 0.568
I45 Other conduction disorders
0.000 0.432 0.568
C73 Malignant neoplasm of thyroid gland
0.000 0.433 0.567
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.433 0.567
N72 Inflammatory disease of cervix uteri
0.000 0.433 0.567
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.000 0.433 0.567
M72 Fibroblastic disorders
0.000 0.433 0.567
K04 Diseases of pulp and periapical tissues
0.000 0.433 0.567
I23 Certain current complications following acute myocardial infarction
0.000 0.434 0.566
I52 Other heart disorders in diseases classified elsewhere
0.000 0.434 0.566
I48 Atrial fibrillation and flutter
0.000 0.434 0.566
I41 Myocarditis in diseases classified elsewhere
0.000 0.434 0.566
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.434 0.566
I32 Pericarditis in diseases classified elsewhere
0.000 0.434 0.566
M54.5 Low back pain
0.000 0.434 0.566
Z48.0 Attention to surgical dressings and sutures
0.000 0.434 0.565
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.435 0.565
K01 Embedded and impacted teeth
0.000 0.435 0.565
I40 Acute myocarditis
0.000 0.435 0.565
H90-H95 Other disorders of ear
0.000 0.435 0.564
A04 Other bacterial intestinal infections
0.000 0.436 0.564
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.436 0.563
I37 Pulmonary valve disorders
0.000 0.437 0.563
H55-H59 Other disorders of eye and adnexa
0.000 0.437 0.562
I50 Heart failure
0.000 0.437 0.562
Z96 Presence of other functional implants
0.001 0.438 0.562
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.439 0.561
M50 Cervical disk disorders
0.000 0.440 0.560
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.000 0.440 0.560
Z59 Problems related to housing and economic circumstances
0.000 0.440 0.560
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.000 0.440 0.559
Z99.8 Dependence on other enabling machines and devices
0.000 0.441 0.559
G57 Mononeuropathies of lower limb
0.000 0.441 0.559
N73 Other female pelvic inflammatory diseases
0.000 0.441 0.559
I30 Acute pericarditis
0.000 0.441 0.558
K29 Gastritis and duodenitis
0.000 0.441 0.558
I33 Acute and subacute endocarditis
0.000 0.442 0.558
H60-H62 Diseases of external ear
0.000 0.442 0.558
Z89.2 Acquired absence of upper limb above wrist
0.000 0.442 0.558
Z42.0 Follow-up care involving plastic surgery of head and neck
0.000 0.442 0.558
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.443 0.557
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.000 0.443 0.557
M45 Ankylosing spondylitis
0.000 0.443 0.557
Z80.3 Family history of malignant neoplasm of breast
0.000 0.443 0.557
D60-D64 Aplastic and other anaemias
0.000 0.443 0.556
Z83.7 Family history of diseases of the digestive system
0.000 0.443 0.556
N76 Other inflammation of vagina and vulva
0.000 0.443 0.556
K12 Stomatitis and related lesions
0.000 0.444 0.556
C07 Malignant neoplasm of parotid gland
0.000 0.444 0.556
K81 Cholecystitis
0.000 0.444 0.555
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.000 0.445 0.555
M71 Other bursopathies
0.000 0.445 0.555
Z80.6 Family history of leukaemia
0.000 0.445 0.555
K70-K77 Diseases of liver
0.000 0.445 0.555
N32.9 Bladder disorder, unspecified
0.000 0.445 0.555
C75 Malignant neoplasm of other endocrine glands and related structures
0.000 0.445 0.555
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.000 0.445 0.555
C74 Malignant neoplasm of adrenal gland
0.000 0.445 0.555
K30 Dyspepsia
0.000 0.446 0.554
Z89.6 Acquired absence of leg above knee
0.000 0.446 0.554
I60 Subarachnoid haemorrhage
0.000 0.446 0.554
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.000 0.446 0.554
D73 Diseases of spleen
0.000 0.446 0.554
Z13.6 Special screening examination for cardiovascular disorders
0.000 0.446 0.554
K60.1 Chronic anal fissure
0.000 0.446 0.554
K09 Cysts of oral region, not elsewhere classified
0.000 0.447 0.553
Z93.1 Gastrostomy status
0.000 0.447 0.553
N40-N51 Diseases of male genital organs
0.000 0.447 0.553
C01 Malignant neoplasm of base of tongue
0.000 0.447 0.553
L40-L45 Papulosquamous disorders
0.000 0.447 0.553
H43-H45 Disorders of vitreous body and globe
0.000 0.447 0.553
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.447 0.552
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.000 0.448 0.552
C05 Malignant neoplasm of palate
0.000 0.449 0.551
I24 Other acute ischaemic heart diseases
0.000 0.449 0.551
Z84.3 Family history of consanguinity
0.000 0.449 0.551
I34 Nonrheumatic mitral valve disorders
0.000 0.449 0.551
I51 Complications and ill-defined descriptions of heart disease
0.000 0.449 0.551
Z47.9 Orthopaedic follow-up care, unspecified
0.000 0.449 0.550
C16 Malignant neoplasm of stomach
0.000 0.450 0.550
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.000 0.450 0.550
I44.7 Left bundle-branch block, unspecified
0.000 0.450 0.550
Z80.4 Family history of malignant neoplasm of genital organs
0.000 0.450 0.549
N70 Salpingitis and oophoritis
0.000 0.451 0.549
C20 Malignant neoplasm of rectum
0.000 0.452 0.548
Z63 Other problems related to primary support group, including family circumstances
0.000 0.452 0.548
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.000 0.452 0.548
Z80.5 Family history of malignant neoplasm of urinary tract
0.000 0.452 0.548
Z62 Other problems related to upbringing
0.000 0.452 0.548
Z55 Problems related to education and literacy
0.000 0.452 0.548
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.452 0.548
Z83.0 Family history of human immunodeficiency virus [HIV]
0.000 0.452 0.547
Z84.8 Family history of other specified conditions
0.000 0.453 0.547
Z65 Problems related to other psychosocial circumstances
0.000 0.453 0.547
I61 Intracerebral haemorrhage
0.000 0.453 0.547
Z80.9 Family history of malignant neoplasm, unspecified
0.000 0.454 0.546
I38 Endocarditis, valve unspecified
0.000 0.454 0.546
Z64 Problems related to certain psychosocial circumstances
0.000 0.454 0.546
Z61 Problems related to negative life events in childhood
0.000 0.454 0.546
Z83.6 Family history of diseases of the respiratory system
0.000 0.454 0.546
Z83.1 Family history of other infectious and parasitic diseases
0.000 0.454 0.546
M77 Other enthesopathies
0.000 0.454 0.545
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.455 0.545
K26 Duodenal ulcer
0.000 0.455 0.545
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.000 0.455 0.545
R07.3 Other chest pain
0.000 0.455 0.545
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.000 0.455 0.544
H80-H83 Diseases of inner ear
0.000 0.455 0.544
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.456 0.544
K60.2 Anal fissure, unspecified
0.000 0.456 0.544
Z58 Problems related to physical environment
0.000 0.456 0.543
F32 Depressive episode
0.000 0.456 0.544
I44.0 Atrioventricular block, first degree
0.000 0.457 0.543
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.457 0.543

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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