TreeWAS – Variant ID: rs10198175

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C15-C26 Malignant neoplasms of digestive organs	0.323	0.677	0.000
C25 Malignant neoplasm of pancreas	0.310	0.690	0.000
C18 Malignant neoplasm of colon	0.308	0.692	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.302	0.698	0.000
C18.2 Ascending colon	0.288	0.712	0.000
C20 Malignant neoplasm of rectum	0.285	0.715	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.284	0.716	0.000
C15 Malignant neoplasm of oesophagus	0.280	0.720	0.000
C18.9 Colon, unspecified	0.279	0.721	0.000
C25.2 Tail of pancreas	0.271	0.729	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.262	0.738	0.000
C21 Malignant neoplasm of anus and anal canal	0.261	0.739	0.000
C25.0 Head of pancreas	0.259	0.741	0.000
C22.0 Liver cell carcinoma	0.254	0.746	0.000
C25.9 Pancreas, unspecified	0.250	0.749	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.250	0.750	0.000
C25.1 Body of pancreas	0.248	0.752	0.000
C18.0 Caecum	0.246	0.754	0.000
C23 Malignant neoplasm of gallbladder	0.246	0.754	0.000
C18.8 Overlapping lesion of colon	0.244	0.756	0.000
C25.3 Pancreatic duct	0.236	0.764	0.000
C25.4 Endocrine pancreas	0.235	0.765	0.000
C16 Malignant neoplasm of stomach	0.235	0.765	0.000
C18.5 Splenic flexure	0.225	0.775	0.000
C15.9 Oesophagus, unspecified	0.223	0.777	0.000
C24.0 Extrahepatic bile duct	0.221	0.779	0.000
C15.3 Upper third of oesophagus	0.218	0.781	0.000
C25.7 Other parts of pancreas	0.216	0.784	0.000
C22.1 Intrahepatic bile duct carcinoma	0.216	0.784	0.000
C18.6 Descending colon	0.216	0.784	0.000
C15.1 Thoracic part of oesophagus	0.216	0.784	0.000
C15.0 Cervical part of oesophagus	0.214	0.786	0.000
C26.0 Intestinal tract, part unspecified	0.213	0.787	0.000
C15.4 Middle third of oesophagus	0.205	0.795	0.000
C25.8 Overlapping lesion of pancreas	0.204	0.796	0.000
C22.7 Other specified carcinomas of liver	0.204	0.796	0.000
C22.4 Other sarcomas of liver	0.204	0.796	0.000
C22.3 Angiosarcoma of liver	0.204	0.796	0.000
C22.2 Hepatoblastoma	0.204	0.796	0.000
C18.7 Sigmoid colon	0.204	0.796	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.204	0.796	0.000
C21.0 Anus, unspecified	0.203	0.797	0.000
C15.8 Overlapping lesion of oesophagus	0.201	0.799	0.000
C15.2 Abdominal part of oesophagus	0.201	0.799	0.000
C22.9 Liver, unspecified	0.199	0.801	0.000
C18.4 Transverse colon	0.198	0.802	0.000
C15.5 Lower third of oesophagus	0.194	0.806	0.000
C18.3 Hepatic flexure	0.191	0.809	0.000
C24.1 Ampulla of Vater	0.189	0.810	0.000
C24.8 Overlapping lesion of biliary tract	0.188	0.812	0.000
C16.3 Pyloric antrum	0.188	0.812	0.000
C16.2 Body of stomach	0.188	0.812	0.000
C21.2 Cloacogenic zone	0.187	0.813	0.000
C21.1 Anal canal	0.186	0.813	0.000
C24.9 Biliary tract, unspecified	0.183	0.817	0.000
C16.6 Greater curvature of stomach, unspecified	0.181	0.819	0.000
C26.8 Overlapping lesion of digestive system	0.180	0.820	0.000
C26.1 Spleen	0.180	0.820	0.000
C18.1 Appendix	0.179	0.821	0.000
C16.4 Pylorus	0.169	0.830	0.000
C16.8 Overlapping lesion of stomach	0.169	0.831	0.000
C16.1 Fundus of stomach	0.165	0.835	0.000
C17 Malignant neoplasm of small intestine	0.160	0.840	0.000
C16.5 Lesser curvature of stomach, unspecified	0.154	0.846	0.000
C26.9 Ill-defined sites within the digestive system	0.153	0.847	0.000
C16.9 Stomach, unspecified	0.148	0.852	0.000
C16.0 Cardia	0.139	0.861	0.000
C17.8 Overlapping lesion of small intestine	0.115	0.885	0.000
C17.3 Meckel's diverticulum	0.115	0.885	0.000
C17.0 Duodenum	0.112	0.887	0.000
C17.1 Jejunum	0.111	0.888	0.000
C17.9 Small intestine, unspecified	0.095	0.904	0.000
C17.2 Ileum	0.087	0.913	0.001
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.019	0.981	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.985	0.015
C34.0 Main bronchus	0.000	0.985	0.015
C34 Malignant neoplasm of bronchus and lung	0.000	0.986	0.014
C34.3 Lower lobe, bronchus or lung	0.000	0.987	0.013
I84.8 Unspecified haemorrhoids with other complications	0.000	0.988	0.012
C34.8 Overlapping lesion of bronchus and lung	0.000	0.989	0.011
C34.2 Middle lobe, bronchus or lung	0.000	0.989	0.011
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.990	0.010
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.991	0.009
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.992	0.008
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.992	0.008
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.992	0.008
R20.2 Paraesthesia of skin	0.008	0.992	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.993	0.007
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.993	0.007
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.993	0.007
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.993	0.007
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.993	0.006
M84 Disorders of continuity of bone	0.000	0.994	0.006
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.994	0.006
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.994	0.006
M84.0 Malunion of fracture	0.000	0.994	0.006
M84.8 Other disorders of continuity of bone	0.000	0.994	0.005
M84.06 Malunion of fracture (Lower leg)	0.000	0.995	0.005
C32 Malignant neoplasm of larynx	0.000	0.995	0.005
M84.9 Disorder of continuity of bone, unspecified	0.000	0.995	0.005
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.005	0.995	0.000
M84.08 Malunion of fracture (Other)	0.000	0.995	0.005
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.995	0.005
M84.04 Malunion of fracture (Hand)	0.000	0.995	0.005
M84.2 Delayed union of fracture	0.000	0.995	0.005
M84.4 Pathological fracture, not elsewhere classified	0.000	0.995	0.005
C32.0 Glottis	0.000	0.995	0.005
C31 Malignant neoplasm of accessory sinuses	0.000	0.995	0.004
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.995	0.004
M84.3 Stress fracture, not elsewhere classified	0.000	0.995	0.004
C32.1 Supraglottis	0.000	0.995	0.004
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.995	0.004
C33 Malignant neoplasm of trachea	0.000	0.996	0.004
C32.2 Subglottis	0.000	0.996	0.004
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.996	0.004
C37 Malignant neoplasm of thymus	0.000	0.996	0.004
M84.09 Malunion of fracture (Site unspecified)	0.000	0.996	0.004
M84.00 Malunion of fracture (Multiple sites)	0.000	0.996	0.004
M84.02 Malunion of fracture (Upper arm)	0.000	0.996	0.004
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.996	0.004
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.996	0.004
M84.88 Other disorders of continuity of bone (Other)	0.000	0.996	0.004
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.996	0.004
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.996	0.004
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.996	0.004
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.996	0.004
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.996	0.004
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.996	0.004
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.996	0.004
N41.1 Chronic prostatitis	0.004	0.996	0.000
C32.8 Overlapping lesion of larynx	0.000	0.996	0.004
C32.9 Larynx, unspecified	0.000	0.996	0.004
M84.01 Malunion of fracture (Shoulder region)	0.000	0.996	0.004
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.996	0.004
N61 Inflammatory disorders of breast	0.004	0.996	0.000
C32.3 Laryngeal cartilage	0.000	0.996	0.004
M84.26 Delayed union of fracture (Lower leg)	0.000	0.996	0.004
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.004	0.996	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.996	0.004
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.996	0.004
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.996	0.004
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.996	0.004
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.996	0.004
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.996	0.004
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.996	0.004
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.996	0.004
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.996	0.004
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.996	0.004
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.996	0.004
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.996	0.003
M84.28 Delayed union of fracture (Other)	0.000	0.996	0.003
M84.24 Delayed union of fracture (Hand)	0.000	0.996	0.003
M84.23 Delayed union of fracture (Forearm)	0.000	0.996	0.003
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.996	0.003
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.996	0.003
S30.0 Contusion of lower back and pelvis	0.000	0.996	0.004
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.996	0.003
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.996	0.003
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.996	0.003
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.996	0.003
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.996	0.003
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.996	0.003
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.996	0.003
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.996	0.003
C31.0 Maxillary sinus	0.000	0.996	0.003
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.003
C31.9 Accessory sinus, unspecified	0.000	0.996	0.003
C31.8 Overlapping lesion of accessory sinuses	0.000	0.996	0.003
C31.3 Sphenoidal sinus	0.000	0.996	0.003
C31.2 Frontal sinus	0.000	0.996	0.003
C31.1 Ethmoidal sinus	0.000	0.996	0.003
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.996	0.003
C39.9 Ill-defined sites within the respiratory system	0.000	0.996	0.003
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.996	0.003
C39.0 Upper respiratory tract, part unspecified	0.000	0.996	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.996	0.003
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.996	0.003
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.996	0.003
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.003
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.996	0.003
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.996	0.003
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.996	0.003
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.996	0.003
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.996	0.003
M84.22 Delayed union of fracture (Upper arm)	0.000	0.996	0.003
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.000	0.997	0.003
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.997	0.003
C38.4 Pleura	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.997	0.003
C38.2 Posterior mediastinum	0.000	0.997	0.003
C38.1 Anterior mediastinum	0.000	0.997	0.003
C38.0 Heart	0.000	0.997	0.003
D51.3 Other dietary vitamin B12 deficiency anaemia	0.003	0.997	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
D51.8 Other vitamin B12 deficiency anaemias	0.003	0.997	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.997	0.003
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.997	0.003
C30.1 Middle ear	0.000	0.997	0.003
C38.3 Mediastinum, part unspecified	0.000	0.997	0.003
M41.9 Scoliosis, unspecified	0.000	0.997	0.003
T42.4 Benzodiazepines	0.003	0.997	0.000
D51.2 Transcobalamin II deficiency	0.003	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.997	0.003
H81.0 Meniere's disease	0.003	0.997	0.000
I49.9 Cardiac arrhythmia, unspecified	0.000	0.997	0.003
M10.97 Gout, unspecified (Ankle and foot)	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
K26 Duodenal ulcer	0.003	0.997	0.000
K26.3 Acute without haemorrhage or perforation	0.003	0.997	0.000
T40.2 Other opioids	0.003	0.997	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.003	0.997	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.997	0.003
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
K66.0 Peritoneal adhesions	0.000	0.997	0.003
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.997	0.002
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.997	0.002
H33.2 Serous retinal detachment	0.000	0.997	0.003
C30.0 Nasal cavity	0.001	0.997	0.002
T40.6 Other and unspecified narcotics	0.003	0.997	0.000
M10.90 Gout, unspecified (Multiple sites)	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
N41 Inflammatory diseases of prostate	0.003	0.997	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.997	0.002
N41.0 Acute prostatitis	0.002	0.997	0.000
T42.0 Hydantoin derivatives	0.002	0.997	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
H33.0 Retinal detachment with retinal break	0.000	0.998	0.002
M10.9 Gout, unspecified	0.002	0.998	0.000
N76.2 Acute vulvitis	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
G30 Alzheimer's disease	0.000	0.998	0.002
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.002
T40.5 Cocaine	0.002	0.998	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.998	0.002
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.000	0.998	0.002
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M10.96 Gout, unspecified (Lower leg)	0.002	0.998	0.000
K26.2 Acute with both haemorrhage and perforation	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
M10.92 Gout, unspecified (Upper arm)	0.002	0.998	0.000
N21.0 Calculus in bladder	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
G30.8 Other Alzheimer's disease	0.000	0.998	0.002
N76.0 Acute vaginitis	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
M10.93 Gout, unspecified (Forearm)	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.002	0.998	0.000
N41.8 Other inflammatory diseases of prostate	0.002	0.998	0.000
N41.3 Prostatocystitis	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
N41.2 Abscess of prostate	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.998	0.002
N76.3 Subacute and chronic vulvitis	0.000	0.998	0.002
C73 Malignant neoplasm of thyroid gland	0.000	0.998	0.002
C74.9 Adrenal gland, unspecified	0.000	0.998	0.002
K26.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
M10.98 Gout, unspecified (Other)	0.002	0.998	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M10.91 Gout, unspecified (Shoulder region)	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
K26.1 Acute with perforation	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.002	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
C74.0 Cortex of adrenal gland	0.000	0.998	0.002
K26.5 Chronic or unspecified with perforation	0.002	0.998	0.000
C74 Malignant neoplasm of adrenal gland	0.000	0.998	0.002
H81.3 Other peripheral vertigo	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
N76 Other inflammation of vagina and vulva	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
H33 Retinal detachments and breaks	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.002	0.998	0.000
R20 Disturbances of skin sensation	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.998	0.002
I49.8 Other specified cardiac arrhythmias	0.000	0.998	0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.000	0.998	0.002
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
M10.94 Gout, unspecified (Hand)	0.002	0.998	0.000
C74.1 Medulla of adrenal gland	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
A04.7 Enterocolitis due to Clostridium difficile	0.002	0.998	0.000
H33.4 Traction detachment of retina	0.000	0.998	0.002
N76.4 Abscess of vulva	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
R10.2 Pelvic and perineal pain	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.002
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
R23.4 Changes in skin texture	0.002	0.998	0.000
S00.0 Superficial injury of scalp	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.998	0.002
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
R23.2 Flushing	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
T37.5 Antiviral drugs	0.001	0.998	0.000
T37.4 Anthelminthics	0.001	0.998	0.000
T37.3 Other antiprotozoal drugs	0.001	0.998	0.000
T37.1 Antimycobacterial drugs	0.001	0.998	0.000
T37.0 Sulphonamides	0.001	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
N76.6 Ulceration of vulva	0.000	0.998	0.002
T39.0 Salicylates	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
T47.7 Emetics	0.001	0.998	0.000
T47.5 Digestants	0.001	0.998	0.000
T47.3 Saline and osmotic laxatives	0.001	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
T41.5 Therapeutic gases	0.001	0.998	0.000
T41.4 Anaesthetic, unspecified	0.001	0.998	0.000
T41.3 Local anaesthetics	0.001	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
T41.1 Intravenous anaesthetics	0.001	0.998	0.000
T41.0 Inhaled anaesthetics	0.001	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
T48.4 Expectorants	0.001	0.998	0.000
T48.3 Antitussives	0.001	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
T48.0 Oxytocic drugs	0.001	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
K26.0 Acute with haemorrhage	0.001	0.998	0.000
T48.5 Anti-common-cold drugs	0.001	0.998	0.000
R23.0 Cyanosis	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
H33.5 Other retinal detachments	0.000	0.998	0.002
N76.5 Ulceration of vagina	0.000	0.998	0.001
R20.1 Hypoaesthesia of skin	0.001	0.998	0.000
R20.0 Anaesthesia of skin	0.001	0.998	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.000	0.998	0.001
Y84.8 Other medical procedures	0.002	0.998	0.000
L40.5 Arthropathic psoriasis	0.002	0.998	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.001	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.001	0.998	0.000
T36.6 Rifamycins	0.001	0.998	0.000
T36.5 Aminoglycosides	0.001	0.998	0.000
T36.2 Chloramphenicol group	0.001	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.001	0.998	0.000
T49.9 Topical agent, unspecified	0.001	0.998	0.000
T49.8 Other topical agents	0.001	0.998	0.000
T49.7 Dental drugs, topically applied	0.001	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.998	0.000
T49.2 Local astringents and local detergents	0.001	0.998	0.000
T49.1 Antipruritics	0.001	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.001	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.998	0.001
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.998	0.001
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.998	0.001
T36.4 Tetracyclines	0.001	0.998	0.000
Z81.8 Family history of other mental and behavioural disorders	0.000	0.998	0.002
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.001
T36.8 Other systemic antibiotics	0.001	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.000	0.998	0.001
N76.8 Other specified inflammation of vagina and vulva	0.000	0.998	0.001
T36.3 Macrolides	0.001	0.998	0.000
T36.0 Penicillins	0.001	0.998	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.000	0.998	0.001
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.998	0.001
T45.0 Antiallergic and antiemetic drugs	0.001	0.998	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.998	0.001
O00.1 Tubal pregnancy	0.001	0.998	0.000
Z39.1 Care and examination of lactating mother	0.001	0.998	0.000
M85 Other disorders of bone density and structure	0.000	0.998	0.001
M80.8 Other osteoporosis with pathological fracture	0.000	0.998	0.001
T47.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
I49 Other cardiac arrhythmias	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.001	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
H81.2 Vestibular neuronitis	0.001	0.999	0.000
M85.9 Disorder of bone density and structure, unspecified	0.000	0.999	0.001
T45.9 Primarily systemic and haematological agent, unspecified	0.001	0.999	0.000
T45.8 Other primarily systemic and haematological agents	0.001	0.999	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.999	0.000
T45.6 Fibrinolysis-affecting drugs	0.001	0.999	0.000
T45.3 Enzymes, not elsewhere classified	0.001	0.999	0.000
T91.1 Sequelae of fracture of spine	0.001	0.999	0.000
M41 Scoliosis	0.000	0.999	0.001
G61.1 Serum neuropathy	0.001	0.999	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.999	0.001
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
M10 Gout	0.001	0.999	0.000
M83 Adult osteomalacia	0.000	0.999	0.001
T45.4 Iron and its compounds	0.001	0.999	0.000
T45.2 Vitamins, not elsewhere classified	0.001	0.999	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
V23.4 Driver injured in traffic accident	0.001	0.999	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
M10.99 Gout, unspecified (Site unspecified)	0.001	0.999	0.000
R20.3 Hyperaesthesia	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations