TreeWAS – Variant ID: rs10218452

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G43.9 Migraine, unspecified	0.958	0.042	0.000
G43 Migraine	0.443	0.556	0.000
G43.1 Migraine with aura [classical migraine]	0.353	0.647	0.000
G43.3 Complicated migraine	0.338	0.662	0.000
G43.2 Status migrainosus	0.318	0.682	0.000
G43.8 Other migraine	0.254	0.745	0.000
G43.0 Migraine without aura [common migraine]	0.254	0.746	0.000
G40-G47 Episodic and paroxysmal disorders	0.177	0.823	0.000
G44 Other headache syndromes	0.171	0.829	0.000
G44.2 Tension-type headache	0.164	0.835	0.000
G44.0 Cluster headache syndrome	0.155	0.845	0.000
G41 Status epilepticus	0.138	0.862	0.000
G44.1 Vascular headache, not elsewhere classified	0.136	0.864	0.000
G44.3 Chronic posttraumatic headache	0.123	0.877	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.123	0.877	0.000
G41.0 Grand mal status epilepticus	0.110	0.890	0.000
G47 Sleep disorders	0.107	0.893	0.000
G44.8 Other specified headache syndromes	0.105	0.895	0.000
G41.9 Status epilepticus, unspecified	0.100	0.900	0.000
G41.8 Other status epilepticus	0.099	0.900	0.000
G41.2 Complex partial status epilepticus	0.099	0.900	0.000
G41.1 Petit mal status epilepticus	0.099	0.900	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.092	0.908	0.000
G46.4 Cerebellar stroke syndrome	0.092	0.908	0.000
G46.3 Brain stem stroke syndrome	0.090	0.910	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.089	0.911	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.088	0.912	0.000
G46.6 Pure sensory lacunar syndrome	0.088	0.912	0.000
G46.5 Pure motor lacunar syndrome	0.088	0.912	0.000
G46.2 Posterior cerebral artery syndrome	0.088	0.912	0.000
G46.1 Anterior cerebral artery syndrome	0.088	0.912	0.000
G46.0 Middle cerebral artery syndrome	0.088	0.912	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.088	0.912	0.000
G47.8 Other sleep disorders	0.086	0.914	0.000
G47.4 Narcolepsy and cataplexy	0.079	0.921	0.000
G46.7 Other lacunar syndromes	0.076	0.924	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.071	0.929	0.000
G47.2 Disorders of the sleep-wake schedule	0.068	0.932	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.055	0.945	0.000
G45.4 Transient global amnesia	0.054	0.946	0.000
G45.0 Vertebro-basilar artery syndrome	0.053	0.947	0.000
G47.9 Sleep disorder, unspecified	0.053	0.947	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.051	0.949	0.000
G45.3 Amaurosis fugax	0.051	0.949	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.038	0.962	0.000
N92.6 Irregular menstruation, unspecified	0.000	0.974	0.026
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.988	0.012
S72.00 Fracture of neck of femur (closed)	0.000	0.988	0.012
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.990	0.010
G40 Epilepsy	0.008	0.991	0.000
S72.0 Fracture of neck of femur	0.000	0.992	0.008
G47.3 Sleep apnoea	0.008	0.992	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.008	0.992	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.008	0.992	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.006	0.993	0.000
J98.1 Pulmonary collapse	0.000	0.994	0.006
G40.4 Other generalised epilepsy and epileptic syndromes	0.006	0.994	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.006	0.994	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.994	0.006
O16 Unspecified maternal hypertension	0.006	0.994	0.000
O36.9 Maternal care for foetal problem, unspecified	0.006	0.994	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.006	0.994	0.000
M16.0 Primary coxarthrosis, bilateral	0.006	0.994	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.006	0.994	0.000
G40.8 Other epilepsy	0.005	0.994	0.000
S72 Fracture of femur	0.000	0.994	0.005
O72.2 Delayed and secondary postpartum haemorrhage	0.005	0.995	0.000
G40.5 Special epileptic syndromes	0.005	0.995	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.995	0.005
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.995	0.005
S72.4 Fracture of lower end of femur	0.000	0.995	0.005
S72.8 Fractures of other parts of femur	0.000	0.995	0.005
S72.40 Fracture of lower end of femur (closed)	0.000	0.996	0.004
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
S72.1 Pertrochanteric fracture	0.000	0.996	0.004
Q23.1 Congenital insufficiency of aortic valve	0.004	0.996	0.000
S72.7 Multiple fractures of femur	0.000	0.996	0.004
S72.2 Subtrochanteric fracture	0.000	0.996	0.004
S72.9 Fracture of femur, part unspecified	0.000	0.996	0.004
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
H20.8 Other iridocyclitis	0.004	0.996	0.000
S72.80 Fractures of other parts of femur (closed)	0.000	0.996	0.004
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.004	0.996	0.000
S72.3 Fracture of shaft of femur	0.000	0.996	0.004
S72.41 Fracture of lower end of femur (open)	0.000	0.996	0.004
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
I35.9 Aortic valve disorder, unspecified	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
O72 Postpartum haemorrhage	0.004	0.996	0.000
Q24 Other congenital malformations of heart	0.004	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
S72.81 Fractures of other parts of femur (open)	0.000	0.996	0.003
C25.0 Head of pancreas	0.000	0.996	0.004
Z80.9 Family history of malignant neoplasm, unspecified	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.996	0.000
H20 Iridocyclitis	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.001	0.997	0.003
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.003	0.997	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.997	0.003
H20.0 Acute and subacute iridocyclitis	0.003	0.997	0.000
C25.9 Pancreas, unspecified	0.000	0.997	0.003
O72.1 Other immediate postpartum haemorrhage	0.003	0.997	0.000
O72.0 Third-stage haemorrhage	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.997	0.003
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.003	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.997	0.003
S72.21 Subtrochanteric fracture (open)	0.000	0.997	0.003
S72.71 Multiple fractures of femur (open)	0.000	0.997	0.003
S72.70 Multiple fractures of femur (closed)	0.000	0.997	0.003
S72.20 Subtrochanteric fracture (closed)	0.000	0.997	0.003
S72.91 Fracture of femur, part unspecified (open)	0.000	0.997	0.003
C25.2 Tail of pancreas	0.000	0.997	0.003
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.002	0.997	0.001
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.997	0.003
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.997	0.003
O15 Eclampsia	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.000	0.997	0.003
S72.31 Fracture of shaft of femur (open)	0.000	0.997	0.003
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.003	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.003	0.997	0.000
O72.3 Postpartum coagulation defects	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
O14.0 Moderate preeclampsia	0.003	0.997	0.000
M84.06 Malunion of fracture (Lower leg)	0.003	0.997	0.000
Q24.6 Congenital heart block	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Q24.0 Dextrocardia	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
Y45.2 Propionic acid derivatives	0.000	0.997	0.003
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
N80.9 Endometriosis, unspecified	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.997	0.003
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.997	0.003
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
J14 Pneumonia due to Haemophilus influenzae	0.000	0.997	0.003
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
S42.40 Fracture of lower end of humerus (closed)	0.003	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.5 Ebstein's anomaly	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.997	0.003
H20.2 Lens-induced iridocyclitis	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
J09-J18 Influenza and pneumonia	0.000	0.997	0.003
Q44.4 Choledochal cyst	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.997	0.003
Q40.8 Other specified congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.003	0.997	0.000
J10 Influenza due to identified influenza virus	0.000	0.997	0.003
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
O14.2 HELLP syndrome	0.003	0.997	0.000
O14.1 Severe preeclampsia	0.003	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Q96 Turner's syndrome	0.002	0.997	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.997	0.000
Q20.4 Double inlet ventricle	0.002	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.997	0.000
Q20.2 Double outlet left ventricle	0.002	0.997	0.000
Q20.1 Double outlet right ventricle	0.002	0.997	0.000
Q20.0 Common arterial trunk	0.002	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.997	0.000
Q26.1 Persistent left superior vena cava	0.002	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.002	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.997	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.997	0.000
C25.1 Body of pancreas	0.000	0.997	0.002
O15.9 Eclampsia, unspecified as to time period	0.002	0.997	0.000
O15.2 Eclampsia in the puerperium	0.002	0.997	0.000
O15.1 Eclampsia in labour	0.002	0.997	0.000
O15.0 Eclampsia in pregnancy	0.002	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.997	0.000
Q25.1 Coarctation of aorta	0.002	0.997	0.000
O48 Prolonged pregnancy	0.003	0.997	0.000
Q63 Other congenital malformations of kidney	0.002	0.997	0.000
C25.7 Other parts of pancreas	0.000	0.997	0.002
C25.4 Endocrine pancreas	0.000	0.997	0.002
J98.4 Other disorders of lung	0.000	0.997	0.003
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.997	0.000
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
Q10.0 Congenital ptosis	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.002	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
Q40.1 Congenital hiatus hernia	0.002	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
Q44.7 Other congenital malformations of liver	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.002	0.998	0.000
J17 Pneumonia in diseases classified elsewhere	0.000	0.998	0.002
J98 Other respiratory disorders	0.000	0.998	0.002
O12.1 Gestational proteinuria	0.002	0.998	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.000	0.998	0.002
O12.2 Gestational oedema with proteinuria	0.002	0.998	0.000
J12 Viral pneumonia, not elsewhere classified	0.000	0.998	0.002
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.002	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.002	0.998	0.000
Q45.1 Annular pancreas	0.002	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.998	0.002
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.002	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.002	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.002	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.002	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.002	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.002	0.998	0.000
Q90 Down's syndrome	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
Q03 Congenital hydrocephalus	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.998	0.000
Q38.2 Macroglossia	0.002	0.998	0.000
Q38.1 Ankyloglossia	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.998	0.002
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.002	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
J09 Influenza due to certain identified influenza virus	0.000	0.998	0.002
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.000	0.998	0.002
J12.9 Viral pneumonia, unspecified	0.000	0.998	0.002
Q04.6 Congenital cerebral cysts	0.002	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
J10.8 Influenza with other manifestations, influenza virus identified	0.000	0.998	0.002
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
C25.3 Pancreatic duct	0.000	0.998	0.002
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
M06.9 Rheumatoid arthritis, unspecified	0.000	0.998	0.002
Q39.4 Oesophageal web	0.002	0.998	0.000
Q34 Other congenital malformations of respiratory system	0.002	0.998	0.000
Q33 Congenital malformations of lung	0.002	0.998	0.000
Q32 Congenital malformations of trachea and bronchus	0.002	0.998	0.000
Q31 Congenital malformations of larynx	0.002	0.998	0.000
Q30 Congenital malformations of nose	0.002	0.998	0.000
Q37 Cleft palate with cleft lip	0.002	0.998	0.000
Q36 Cleft lip	0.002	0.998	0.000
Q35 Cleft palate	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
Q96.8 Other variants of Turner's syndrome	0.002	0.998	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.002	0.998	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.002	0.998	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.002	0.998	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.002	0.998	0.000
Q96.0 Karyotype 45,X	0.002	0.998	0.000
J98.2 Interstitial emphysema	0.000	0.998	0.002
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.000	0.998	0.002
M84.0 Malunion of fracture	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.002	0.998	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.002	0.998	0.000
O12.0 Gestational oedema	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.998	0.002
Q10.7 Congenital malformation of orbit	0.002	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.998	0.000
Q10.2 Congenital entropion	0.002	0.998	0.000
Q10.1 Congenital ectropion	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
J17.3 Pneumonia in parasitic diseases	0.000	0.998	0.002
Q04.9 Congenital malformation of brain, unspecified	0.002	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.998	0.000
Q04.5 Megalencephaly	0.002	0.998	0.000
Q04.4 Septo-optic dysplasia	0.002	0.998	0.000
Q04.3 Other reduction deformities of brain	0.002	0.998	0.000
Q04.2 Holoprosencephaly	0.002	0.998	0.000
Q04.1 Arhinencephaly	0.002	0.998	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.998	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.000	0.998	0.002
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.000	0.998	0.002
J98.3 Compensatory emphysema	0.000	0.998	0.002
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
J12.8 Other viral pneumonia	0.000	0.998	0.002
J12.3 Human metapneumovirus pneumonia	0.000	0.998	0.002
J12.1 Respiratory syncytial virus pneumonia	0.000	0.998	0.002
J12.0 Adenoviral pneumonia	0.000	0.998	0.002
L89.0 Stage I decubitus ulcer and pressure area	0.002	0.998	0.000
Q63.2 Ectopic kidney	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
J11 Influenza, virus not identified	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
J10.0 Influenza with pneumonia, influenza virus identified	0.000	0.998	0.002
J17.1 Pneumonia in viral diseases classified elsewhere	0.000	0.998	0.002
Q14.1 Congenital malformation of retina	0.002	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
Q74.1 Congenital malformation of knee	0.002	0.998	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.002	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q90.9 Down's syndrome, unspecified	0.002	0.998	0.000
Q90.2 Trisomy 21, translocation	0.002	0.998	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.002	0.998	0.000
Q91.7 Patau's syndrome, unspecified	0.002	0.998	0.000
Q91.6 Trisomy 13, translocation	0.002	0.998	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.002	0.998	0.000
Q91.3 Edwards' syndrome, unspecified	0.002	0.998	0.000
Q91.2 Trisomy 18, translocation	0.002	0.998	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.002	0.998	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.002	0.998	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.002	0.998	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.002	0.998	0.000
Q92.7 Triploidy and polyploidy	0.002	0.998	0.000
Q92.6 Extra marker chromosomes	0.002	0.998	0.000
Q92.5 Duplications with other complex rearrangements	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations