TreeWAS – Variant ID: rs10223052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.951	0.049	0.000
J44 Other chronic obstructive pulmonary disease	0.948	0.052	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.943	0.057	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.876	0.124	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.779	0.221	0.000
J40-J47 Chronic lower respiratory diseases	0.204	0.796	0.000
J47 Bronchiectasis	0.188	0.812	0.000
J42 Unspecified chronic bronchitis	0.175	0.825	0.000
J46 Status asthmaticus	0.150	0.850	0.000
J41 Simple and mucopurulent chronic bronchitis	0.118	0.882	0.000
J40 Bronchitis, not specified as acute or chronic	0.102	0.898	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.085	0.915	0.000
J41.1 Mucopurulent chronic bronchitis	0.085	0.915	0.000
J41.0 Simple chronic bronchitis	0.056	0.943	0.001
J43 Emphysema	0.052	0.948	0.000
J45 Asthma	0.039	0.958	0.002
J43.1 Panlobular emphysema	0.037	0.963	0.000
J43.0 MacLeod's syndrome	0.037	0.963	0.000
J45.1 Nonallergic asthma	0.031	0.968	0.002
J43.8 Other emphysema	0.031	0.969	0.000
J45.8 Mixed asthma	0.027	0.971	0.002
O72.1 Other immediate postpartum haemorrhage	0.000	0.973	0.027
I49.0 Ventricular fibrillation and flutter	0.025	0.975	0.000
J43.2 Centrilobular emphysema	0.022	0.977	0.000
Q61.0 Congenital single renal cyst	0.018	0.982	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.016	0.984	0.000
Q61 Cystic kidney disease	0.016	0.984	0.000
Q61.2 Polycystic kidney, adult type	0.015	0.985	0.000
J45.0 Predominantly allergic asthma	0.001	0.985	0.014
Q61.9 Cystic kidney disease, unspecified	0.013	0.986	0.000
J43.9 Emphysema, unspecified	0.013	0.987	0.000
Q61.5 Medullary cystic kidney	0.012	0.988	0.000
Q61.8 Other cystic kidney diseases	0.012	0.988	0.000
Q61.1 Polycystic kidney, infantile type	0.012	0.988	0.000
Q61.4 Renal dysplasia	0.012	0.988	0.000
Q60-Q64 Congenital malformations of the urinary system	0.010	0.990	0.000
Q61.3 Polycystic kidney, unspecified	0.009	0.991	0.000
K59.0 Constipation	0.008	0.992	0.000
Q64 Other congenital malformations of urinary system	0.008	0.992	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.007	0.993	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.007	0.993	0.000
M79.0 Rheumatism, unspecified	0.007	0.993	0.000
Q63 Other congenital malformations of kidney	0.007	0.993	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.007	0.993	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.007	0.993	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.993	0.007
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.006	0.993	0.000
N61 Inflammatory disorders of breast	0.006	0.994	0.000
M50.1 Cervical disk disorder with radiculopathy	0.006	0.994	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.006	0.994	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.006	0.994	0.000
Q64.8 Other specified congenital malformations of urinary system	0.006	0.994	0.000
Q64.6 Congenital diverticulum of bladder	0.006	0.994	0.000
Q64.5 Congenital absence of bladder and urethra	0.006	0.994	0.000
Q64.2 Congenital posterior urethral valves	0.006	0.994	0.000
Q64.1 Exstrophy of urinary bladder	0.006	0.994	0.000
Q64.0 Epispadias	0.006	0.994	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.006	0.994	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.006	0.994	0.000
L71.9 Rosacea, unspecified	0.000	0.994	0.006
M79.01 Rheumatism, unspecified (Shoulder region)	0.006	0.994	0.000
Q60.3 Renal hypoplasia, unilateral	0.006	0.994	0.000
Q64.4 Malformation of urachus	0.005	0.994	0.000
Q24.8 Other specified congenital malformations of heart	0.006	0.994	0.000
Q60.0 Renal agenesis, unilateral	0.006	0.994	0.000
D68.8 Other specified coagulation defects	0.000	0.994	0.006
Q64.7 Other congenital malformations of bladder and urethra	0.005	0.994	0.000
Q60.6 Potter's syndrome	0.005	0.994	0.000
Q60.5 Renal hypoplasia, unspecified	0.005	0.994	0.000
Q60.4 Renal hypoplasia, bilateral	0.005	0.994	0.000
Q60.1 Renal agenesis, bilateral	0.005	0.994	0.000
Q60.2 Renal agenesis, unspecified	0.005	0.995	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.005	0.995	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M79.04 Rheumatism, unspecified (Hand)	0.005	0.995	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.005	0.995	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.005	0.995	0.000
Q63.0 Accessory kidney	0.005	0.995	0.000
Q63.3 Hyperplastic and giant kidney	0.005	0.995	0.000
K59.8 Other specified functional intestinal disorders	0.005	0.995	0.000
K59 Other functional intestinal disorders	0.005	0.995	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.005	0.995	0.000
L29.0 Pruritus ani	0.000	0.995	0.005
Q62.2 Congenital megaloureter	0.005	0.995	0.000
Q62.1 Atresia and stenosis of ureter	0.005	0.995	0.000
Q62.8 Other congenital malformations of ureter	0.005	0.995	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.005	0.995	0.000
Q62.6 Malposition of ureter	0.005	0.995	0.000
Q62.4 Agenesis of ureter	0.005	0.995	0.000
Q62.0 Congenital hydronephrosis	0.005	0.995	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
K59.4 Anal spasm	0.005	0.995	0.000
Q63.8 Other specified congenital malformations of kidney	0.004	0.995	0.000
M79.08 Rheumatism, unspecified (Other)	0.004	0.995	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
Z42 Follow-up care involving plastic surgery	0.004	0.996	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.996	0.004
Y85.0 Sequelae of motor-vehicle accident	0.000	0.996	0.004
Q89.2 Congenital malformations of other endocrine glands	0.004	0.996	0.000
K59.9 Functional intestinal disorder, unspecified	0.004	0.996	0.000
Q62.5 Duplication of ureter	0.004	0.996	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.004	0.996	0.000
D68.5 Primary Thrombophilia	0.000	0.996	0.004
Q63.2 Ectopic kidney	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q89 Other congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.996	0.004
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
D12.0 Caecum	0.000	0.996	0.004
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
I84.1 Internal haemorrhoids with other complications	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
H34.2 Other retinal artery occlusions	0.000	0.996	0.004
N60.1 Diffuse cystic mastopathy	0.004	0.996	0.000
Q89.3 Situs inversus	0.004	0.996	0.000
O72 Postpartum haemorrhage	0.000	0.996	0.004
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
K59.1 Functional diarrhoea	0.004	0.996	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.996	0.004
D68 Other coagulation defects	0.000	0.996	0.004
Q26 Congenital malformations of great veins	0.003	0.996	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.996	0.004
Q98.4 Klinefelter's syndrome, unspecified	0.003	0.996	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.996	0.004
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.003	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.996	0.000
Q25 Congenital malformations of great arteries	0.003	0.996	0.000
K59.2 Neurogenic bowel, not elsewhere classified	0.003	0.996	0.000
Q31 Congenital malformations of larynx	0.003	0.996	0.000
G25.0 Essential tremor	0.003	0.997	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.003	0.997	0.000
Q89.9 Congenital malformation, unspecified	0.003	0.997	0.000
Q89.8 Other specified congenital malformations	0.003	0.997	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q89.4 Conjoined twins	0.003	0.997	0.000
Q89.1 Congenital malformations of adrenal gland	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.997	0.003
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
Q22.5 Ebstein's anomaly	0.003	0.997	0.000
Q89.0 Congenital malformations of spleen	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
K83.1 Obstruction of bile duct	0.000	0.997	0.003
Q31.3 Laryngocele	0.003	0.997	0.000
L71 Rosacea	0.000	0.997	0.003
Q96 Turner's syndrome	0.003	0.997	0.000
L71.1 Rhinophyma	0.000	0.997	0.003
S01.8 Open wound of other parts of head	0.003	0.997	0.000
N60.4 Mammary duct ectasia	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.997	0.003
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
N60 Benign mammary dysplasia	0.003	0.997	0.000
Q21.0 Ventricular septal defect	0.003	0.997	0.000
Q40.2 Other specified congenital malformations of stomach	0.003	0.997	0.000
Q40.1 Congenital hiatus hernia	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
Q67.6 Pectus excavatum	0.003	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.003	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.003	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.003	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.003	0.997	0.000
Q98.5 Karyotype 47,XYY	0.003	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.003	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.003	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.003	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
O72.3 Postpartum coagulation defects	0.000	0.997	0.003
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
C83.3 Large cell (diffuse)	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.997	0.003
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.997	0.003
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.997	0.003
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.997	0.003
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.997	0.003
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.997	0.003
Q67.5 Congenital deformity of spine	0.003	0.997	0.000
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q31.9 Congenital malformation of larynx, unspecified	0.003	0.997	0.000
Q31.8 Other congenital malformations of larynx	0.003	0.997	0.000
Q31.5 Congenital laryngomalacia	0.003	0.997	0.000
Q31.4 Congenital laryngeal stridor	0.003	0.997	0.000
Q31.2 Laryngeal hypoplasia	0.003	0.997	0.000
Q31.1 Congenital subglottic stenosis	0.003	0.997	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.003	0.997	0.000
D04.4 Skin of scalp and neck	0.003	0.997	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.997	0.003
Q30.9 Congenital malformation of nose, unspecified	0.003	0.997	0.000
Q83.3 Accessory nipple	0.003	0.997	0.000
Q90.9 Down's syndrome, unspecified	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q31.0 Web of larynx	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.003	0.997	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.003	0.997	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.003	0.997	0.000
D68.6 Other Thrombophilia	0.000	0.997	0.003
Q21.4 Aortopulmonary septal defect	0.003	0.997	0.000
Q21.2 Atrioventricular septal defect	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
Q82.8 Other specified congenital malformations of skin	0.003	0.997	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.003	0.997	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.997	0.003
Q90.2 Trisomy 21, translocation	0.002	0.997	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.002	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.997	0.003
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
Q39.4 Oesophageal web	0.003	0.997	0.000
Q82.5 Congenital nonneoplastic naevus	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
N60.8 Other benign mammary dysplasias	0.003	0.997	0.000
Q30.8 Other congenital malformations of nose	0.002	0.997	0.000
Q30.2 Fissured, notched and cleft nose	0.002	0.997	0.000
Q30.1 Agenesis and underdevelopment of nose	0.002	0.997	0.000
Q30.0 Choanal atresia	0.002	0.997	0.000
Y85 Sequelae of transport accidents	0.000	0.997	0.003
D68.0 Von Willebrand's disease	0.000	0.997	0.003
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.997	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.002	0.997	0.000
Q82.2 Mastocytosis	0.002	0.997	0.000
Q83.9 Congenital malformation of breast, unspecified	0.002	0.997	0.000
Q83.8 Other congenital malformations of breast	0.002	0.997	0.000
Q83.2 Absent nipple	0.002	0.997	0.000
Q83.0 Congenital absence of breast with absent nipple	0.002	0.997	0.000
N63 Unspecified lump in breast	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.002	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.997	0.000
Q82.9 Congenital malformation of skin, unspecified	0.002	0.997	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.002	0.997	0.000
Q82.3 Incontinentia pigmenti	0.002	0.997	0.000
Q82.1 Xeroderma pigmentosum	0.002	0.997	0.000
Q91.7 Patau's syndrome, unspecified	0.002	0.997	0.000
Q91.6 Trisomy 13, translocation	0.002	0.997	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.002	0.997	0.000
Q91.3 Edwards' syndrome, unspecified	0.002	0.997	0.000
Q91.2 Trisomy 18, translocation	0.002	0.997	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.002	0.997	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.002	0.997	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.002	0.997	0.000
Q92.7 Triploidy and polyploidy	0.002	0.997	0.000
Q92.6 Extra marker chromosomes	0.002	0.997	0.000
Q92.5 Duplications with other complex rearrangements	0.002	0.997	0.000
Q92.4 Duplications seen only at prometaphase	0.002	0.997	0.000
Q92.3 Minor partial trisomy	0.002	0.997	0.000
Q92.2 Major partial trisomy	0.002	0.997	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.002	0.997	0.000
Q93.9 Deletion from autosomes, unspecified	0.002	0.997	0.000
Q93.8 Other deletions from the autosomes	0.002	0.997	0.000
Q93.7 Deletions with other complex rearrangements	0.002	0.997	0.000
Q93.6 Deletions seen only at prometaphase	0.002	0.997	0.000
Q93.5 Other deletions of part of a chromosome	0.002	0.997	0.000
Q93.4 Deletion of short arm of chromosome 5	0.002	0.997	0.000
Q93.3 Deletion of short arm of chromosome 4	0.002	0.997	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.002	0.997	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.002	0.997	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.002	0.997	0.000
Q95.8 Other balanced rearrangements and structural markers	0.002	0.997	0.000
Q95.5 Individuals with autosomal fragile site	0.002	0.997	0.000
Q95.4 Individuals with marker heterochromatin	0.002	0.997	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.002	0.997	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.002	0.997	0.000
Q95.1 Chromosome inversion in normal individual	0.002	0.997	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.002	0.997	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.002	0.997	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.002	0.997	0.000
Q97.3 Female with 46,XY karyotype	0.002	0.997	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.002	0.997	0.000
Q97.1 Female with more than three X chromosomes	0.002	0.997	0.000
Q97.0 Karyotype 47,XXX	0.002	0.997	0.000
Q30.3 Congenital perforated nasal septum	0.002	0.997	0.000
Q67.8 Other congenital deformities of chest	0.002	0.997	0.000
Q67.7 Pectus carinatum	0.002	0.997	0.000
Q67.3 Plagiocephaly	0.002	0.997	0.000
Q67.2 Dolichocephaly	0.002	0.997	0.000
Q67.1 Compression facies	0.002	0.997	0.000
Q67.0 Facial asymmetry	0.002	0.997	0.000
Q80.9 Congenital ichthyosis, unspecified	0.002	0.997	0.000
Q80.8 Other congenital ichthyosis	0.002	0.997	0.000
Q80.4 Harlequin foetus	0.002	0.997	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.002	0.997	0.000
Q80.2 Lamellar ichthyosis	0.002	0.997	0.000
Q80.1 X-linked ichthyosis	0.002	0.997	0.000
Q80.0 Ichthyosis vulgaris	0.002	0.997	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.002	0.997	0.000
Q81.8 Other epidermolysis bullosa	0.002	0.997	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.002	0.997	0.000
Q81.1 Epidermolysis bullosa letalis	0.002	0.997	0.000
Q81.0 Epidermolysis bullosa simplex	0.002	0.997	0.000
Q84.9 Congenital malformation of integument, unspecified	0.002	0.997	0.000
Q84.8 Other specified congenital malformations of integument	0.002	0.997	0.000
Q84.6 Other congenital malformations of nails	0.002	0.997	0.000
Q84.5 Enlarged and hypertrophic nails	0.002	0.997	0.000
Q84.4 Congenital leukonychia	0.002	0.997	0.000
Q84.3 Anonychia	0.002	0.997	0.000
Q84.2 Other congenital malformations of hair	0.002	0.997	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.002	0.997	0.000
Q84.0 Congenital alopecia	0.002	0.997	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.002	0.997	0.000
Q86.2 Dysmorphism due to warfarin	0.002	0.997	0.000
Q86.1 Foetal hydantoin syndrome	0.002	0.997	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.002	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.997	0.000
Q32.4 Other congenital malformations of bronchus	0.002	0.997	0.000
Q32.3 Congenital stenosis of bronchus	0.002	0.997	0.000
Q32.2 Congenital bronchomalacia	0.002	0.997	0.000
Q32.1 Other congenital malformations of trachea	0.002	0.997	0.000
Q32.0 Congenital tracheomalacia	0.002	0.997	0.000
Q33.9 Congenital malformation of lung, unspecified	0.002	0.997	0.000
Q33.8 Other congenital malformations of lung	0.002	0.997	0.000
Q33.6 Hypoplasia and dysplasia of lung	0.002	0.997	0.000
Q33.5 Ectopic tissue in lung	0.002	0.997	0.000
Q33.4 Congenital bronchiectasis	0.002	0.997	0.000
Q33.3 Agenesis of lung	0.002	0.997	0.000
Q33.2 Sequestration of lung	0.002	0.997	0.000
Q33.1 Accessory lobe of lung	0.002	0.997	0.000
Q33.0 Congenital cystic lung	0.002	0.997	0.000
Q34.9 Congenital malformation of respiratory system, unspecified	0.002	0.997	0.000
Q34.8 Other specified congenital malformations of respiratory system	0.002	0.997	0.000
Q34.1 Congenital cyst of mediastinum	0.002	0.997	0.000
Q34.0 Anomaly of pleura	0.002	0.997	0.000
Q76.0 Spina bifida occulta	0.002	0.997	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.997	0.003
L71.0 Perioral dermatitis	0.000	0.997	0.002
Q25.4 Other congenital malformations of aorta	0.002	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.997	0.000
N60-N64 Disorders of breast	0.003	0.997	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.997	0.002
Q96.8 Other variants of Turner's syndrome	0.002	0.997	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.002	0.997	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.002	0.997	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.002	0.997	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.002	0.997	0.000
Q96.0 Karyotype 45,X	0.002	0.997	0.000
Q12 Congenital lens malformations	0.002	0.997	0.000
Q21.3 Tetralogy of Fallot	0.002	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.997	0.000
Q76.5 Cervical rib	0.002	0.997	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.000	0.997	0.002
N60.2 Fibroadenosis of breast	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
Q99.9 Chromosomal abnormality, unspecified	0.002	0.998	0.000
Q99.2 Fragile X chromosome	0.002	0.998	0.000
Q99.1 46,XX true hermaphrodite	0.002	0.998	0.000
Q99.0 Chimera 46,XX/46,XY	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
Q44.4 Choledochal cyst	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.002	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.002	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.002	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.002	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.002	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.002	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.002	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.002	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.002	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.002	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.998	0.000
Q44.2 Atresia of bile ducts	0.002	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
K29.2 Alcoholic gastritis	0.002	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
C02.1 Border of tongue	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations