TreeWAS – Variant ID: rs10239506

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12.3 Transverse colon	0.056	0.944	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.055	0.945	0.000
E20-E35 Disorders of other endocrine glands	0.054	0.946	0.000
E27 Other disorders of adrenal gland	0.054	0.946	0.000
D12.0 Caecum	0.054	0.946	0.000
E23 Hypofunction and other disorders of pituitary gland	0.053	0.947	0.000
D12.8 Rectum	0.052	0.948	0.000
E22 Hyperfunction of pituitary gland	0.052	0.948	0.000
D12.4 Descending colon	0.052	0.948	0.000
D12.2 Ascending colon	0.052	0.948	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.051	0.949	0.000
E23.6 Other disorders of pituitary gland	0.050	0.950	0.000
E29 Testicular dysfunction	0.048	0.952	0.000
E27.1 Primary adrenocortical insufficiency	0.047	0.953	0.000
E23.7 Disorder of pituitary gland, unspecified	0.046	0.954	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.045	0.955	0.000
E27.8 Other specified disorders of adrenal gland	0.045	0.955	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.045	0.955	0.000
E34 Other endocrine disorders	0.043	0.957	0.000
E32 Diseases of thymus	0.043	0.957	0.000
E28 Ovarian dysfunction	0.043	0.957	0.000
E20 Hypoparathyroidism	0.043	0.957	0.000
E31 Polyglandular dysfunction	0.042	0.957	0.000
E29.1 Testicular hypofunction	0.042	0.958	0.000
D12.7 Rectosigmoid junction	0.042	0.958	0.000
E27.9 Disorder of adrenal gland, unspecified	0.042	0.958	0.000
D12.1 Appendix	0.041	0.959	0.000
E23.0 Hypopituitarism	0.040	0.960	0.000
E22.1 Hyperprolactinaemia	0.040	0.960	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.039	0.961	0.000
E30 Disorders of puberty, not elsewhere classified	0.039	0.961	0.000
E27.5 Adrenomedullary hyperfunction	0.039	0.961	0.000
E27.0 Other adrenocortical overactivity	0.039	0.961	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.038	0.962	0.000
E23.1 Drug-induced hypopituitarism	0.038	0.962	0.000
E28.3 Primary ovarian failure	0.038	0.962	0.000
E29.9 Testicular dysfunction, unspecified	0.038	0.962	0.000
E22.8 Other hyperfunction of pituitary gland	0.037	0.962	0.000
E27.2 Addisonian crisis	0.037	0.962	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.036	0.964	0.000
E22.0 Acromegaly and pituitary gigantism	0.036	0.964	0.000
E34.3 Short stature, not elsewhere classified	0.036	0.964	0.000
E23.2 Diabetes insipidus	0.036	0.964	0.000
E25 Adrenogenital disorders	0.035	0.965	0.000
E34.0 Carcinoid syndrome	0.035	0.965	0.000
E32.8 Other diseases of thymus	0.035	0.965	0.000
E26 Hyperaldosteronism	0.035	0.965	0.000
E29.8 Other testicular dysfunction	0.035	0.965	0.000
E29.0 Testicular hyperfunction	0.035	0.965	0.000
E24 Cushing's syndrome	0.035	0.965	0.000
E20.9 Hypoparathyroidism, unspecified	0.034	0.966	0.000
E31.0 Autoimmune polyglandular failure	0.034	0.966	0.000
D12.9 Anus and anal canal	0.033	0.967	0.000
E34.5 Androgen resistance syndrome	0.031	0.969	0.000
E34.4 Constitutional tall stature	0.031	0.969	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.031	0.969	0.000
E34.1 Other hypersecretion of intestinal hormones	0.031	0.969	0.000
E32.9 Disease of thymus, unspecified	0.031	0.969	0.000
E32.1 Abscess of thymus	0.031	0.969	0.000
E32.0 Persistent hyperplasia of thymus	0.031	0.969	0.000
E28.9 Ovarian dysfunction, unspecified	0.031	0.969	0.000
E28.8 Other ovarian dysfunction	0.031	0.969	0.000
E28.1 Androgen excess	0.031	0.969	0.000
E28.0 Oestrogen excess	0.031	0.969	0.000
E20.8 Other hypoparathyroidism	0.031	0.969	0.000
E20.1 Pseudohypoparathyroidism	0.031	0.969	0.000
E20.0 Idiopathic hypoparathyroidism	0.031	0.969	0.000
E31.9 Polyglandular dysfunction, unspecified	0.031	0.969	0.000
E31.8 Other polyglandular dysfunction	0.031	0.969	0.000
E31.1 Polyglandular hyperfunction	0.031	0.969	0.000
E34.8 Other specified endocrine disorders	0.030	0.970	0.000
E30.9 Disorder of puberty, unspecified	0.028	0.972	0.000
E30.8 Other disorders of puberty	0.028	0.972	0.000
E30.1 Precocious puberty	0.028	0.972	0.000
E30.0 Delayed puberty	0.028	0.972	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.028	0.972	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.028	0.972	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.028	0.972	0.000
E24.8 Other Cushing's syndrome	0.028	0.972	0.000
E24.0 Pituitary-dependent Cushing's disease	0.026	0.974	0.000
E25.9 Adrenogenital disorder, unspecified	0.025	0.974	0.000
E25.8 Other adrenogenital disorders	0.025	0.974	0.000
E34.9 Endocrine disorder, unspecified	0.025	0.974	0.000
E26.8 Other hyperaldosteronism	0.025	0.975	0.000
E26.1 Secondary hyperaldosteronism	0.025	0.975	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.025	0.975	0.000
E24.3 Ectopic ACTH syndrome	0.025	0.975	0.000
E24.1 Nelson's syndrome	0.025	0.975	0.000
E26.9 Hyperaldosteronism, unspecified	0.025	0.975	0.000
E24.2 Drug-induced Cushing's syndrome	0.024	0.975	0.000
E28.2 Polycystic ovarian syndrome	0.023	0.977	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.021	0.978	0.000
E26.0 Primary hyperaldosteronism	0.021	0.979	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.018	0.981	0.000
E83.4 Disorders of magnesium metabolism	0.018	0.982	0.000
E21.4 Other specified disorders of parathyroid gland	0.015	0.985	0.000
E24.9 Cushing's syndrome, unspecified	0.014	0.985	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.013	0.987	0.000
E21.2 Other hyperparathyroidism	0.013	0.987	0.000
E83.1 Disorders of iron metabolism	0.013	0.987	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.013	0.987	0.000
E83 Disorders of mineral metabolism	0.012	0.988	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.012	0.988	0.000
M85.8 Other specified disorders of bone density and structure	0.012	0.988	0.000
Z63.4 Disappearance and death of family member	0.012	0.988	0.000
T78.4 Allergy, unspecified	0.000	0.989	0.011
M85.88 Other specified disorders of bone density and structure (Other)	0.011	0.989	0.000
Z63 Other problems related to primary support group, including family circumstances	0.010	0.990	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.010	0.990	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.010	0.990	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.990	0.010
E21.3 Hyperparathyroidism, unspecified	0.010	0.990	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.990	0.010
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.010	0.990	0.000
Z63.7 Other stressful life events affecting family and household	0.009	0.991	0.000
E83.8 Other disorders of mineral metabolism	0.009	0.991	0.000
E83.2 Disorders of zinc metabolism	0.009	0.991	0.000
E83.0 Disorders of copper metabolism	0.009	0.991	0.000
Z63.8 Other specified problems related to primary support group	0.009	0.991	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.009	0.991	0.000
Z63.6 Dependent relative needing care at home	0.009	0.991	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.009	0.991	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.009	0.991	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.009	0.991	0.000
E83.3 Disorders of phosphorus metabolism	0.009	0.991	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.008	0.992	0.000
T78.8 Other adverse effects, not elsewhere classified	0.000	0.992	0.008
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.008	0.992	0.000
T78.9 Adverse effect, unspecified	0.000	0.992	0.008
M85 Other disorders of bone density and structure	0.008	0.992	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.008	0.992	0.000
M85.0 Fibrous dysplasia (monostotic)	0.008	0.992	0.000
Z63.9 Problem related to primary support group, unspecified	0.007	0.992	0.000
Z63.3 Absence of family member	0.007	0.992	0.000
Z63.2 Inadequate family support	0.007	0.992	0.000
Z63.1 Problems in relationship with parents and in-laws	0.007	0.992	0.000
S69.9 Unspecified injury of wrist and hand	0.000	0.992	0.008
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.007	0.993	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.993	0.007
Z63.0 Problems in relationship with spouse or partner	0.007	0.993	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.007	0.993	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.007	0.993	0.000
M85.2 Hyperostosis of skull	0.006	0.994	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.006	0.994	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.006	0.994	0.000
Z63.5 Disruption of family by separation and divorce	0.006	0.994	0.000
Z59 Problems related to housing and economic circumstances	0.006	0.994	0.000
H26.8 Other specified cataract	0.000	0.994	0.006
M85.5 Aneurysmal bone cyst	0.006	0.994	0.000
M85.3 Osteitis condensans	0.006	0.994	0.000
M85.1 Skeletal fluorosis	0.006	0.994	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.006	0.994	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.006	0.994	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.006	0.994	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.006	0.994	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.006	0.994	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.006	0.994	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.006	0.994	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.006	0.994	0.000
Z61 Problems related to negative life events in childhood	0.006	0.994	0.000
M85.9 Disorder of bone density and structure, unspecified	0.006	0.994	0.000
T66 Unspecified effects of radiation	0.000	0.994	0.006
T78.3 Angioneurotic oedema	0.000	0.994	0.006
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.994	0.005
T66-T78 Other and unspecified effects of external causes	0.000	0.994	0.006
M07.36 Other psoriatic arthropathies (Lower leg)	0.005	0.995	0.000
M85.22 Hyperostosis of skull-Upper arm	0.005	0.995	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.005	0.995	0.000
M07.3 Other psoriatic arthropathies	0.005	0.995	0.000
Z58 Problems related to physical environment	0.005	0.995	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.005	0.995	0.000
R59.0 Localised enlarged lymph nodes	0.005	0.995	0.000
M85.4 Solitary bone cyst	0.005	0.995	0.000
M85.6 Other cyst of bone	0.005	0.995	0.000
R57.2 Septic shock	0.005	0.995	0.000
Z65 Problems related to other psychosocial circumstances	0.005	0.995	0.000
M85.20 Hyperostosis of skull-Mult sites	0.005	0.995	0.000
M85.29 Hyperostosis of skull-Site unspec	0.005	0.995	0.000
M85.28 Hyperostosis of skull-Other	0.005	0.995	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.005	0.995	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.005	0.995	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.005	0.995	0.000
M85.24 Hyperostosis of skull-Hand	0.005	0.995	0.000
M85.23 Hyperostosis of skull-Forearm	0.005	0.995	0.000
M85.21 Hyperostosis of skull-Shldr region	0.005	0.995	0.000
R27.0 Ataxia, unspecified	0.005	0.995	0.000
Z62 Other problems related to upbringing	0.005	0.995	0.000
Z55 Problems related to education and literacy	0.005	0.995	0.000
Z59.1 Inadequate housing	0.005	0.995	0.000
Z59.0 Homelessness	0.005	0.995	0.000
Z60 Problems related to social environment	0.005	0.995	0.000
M07.38 Other psoriatic arthropathies (Other)	0.005	0.995	0.000
S69 Other and unspecified injuries of wrist and hand	0.000	0.995	0.005
S69.8 Other specified injuries of wrist and hand	0.000	0.995	0.005
Z59.8 Other problems relating to housing and economic circumstances	0.004	0.995	0.000
Z58.8 Other problems related to physical environment	0.004	0.995	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.004	0.995	0.000
Z64 Problems related to certain psychosocial circumstances	0.004	0.995	0.000
Z59.7 Insufficient social insurance and welfare support	0.004	0.996	0.000
Z59.6 Low income	0.004	0.996	0.000
Z59.5 Extreme poverty	0.004	0.996	0.000
Z59.4 Lack of adequate food	0.004	0.996	0.000
Z59.3 Problems related to living in residential institution	0.004	0.996	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.004	0.996	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.004	0.996	0.000
M85.18 Skeletal fluorosis (Other)	0.004	0.996	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.004	0.996	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.004	0.996	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.004	0.996	0.000
M85.14 Skeletal fluorosis (Hand)	0.004	0.996	0.000
M85.13 Skeletal fluorosis (Forearm)	0.004	0.996	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.004	0.996	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.004	0.996	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.004	0.996	0.000
M85.39 Osteitis condensans (Site unspecified)	0.004	0.996	0.000
M85.38 Osteitis condensans (Other)	0.004	0.996	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.004	0.996	0.000
M85.36 Osteitis condensans (Lower leg)	0.004	0.996	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.004	0.996	0.000
M85.34 Osteitis condensans (Hand)	0.004	0.996	0.000
M85.33 Osteitis condensans (Forearm)	0.004	0.996	0.000
M85.32 Osteitis condensans (Upper arm)	0.004	0.996	0.000
M85.31 Osteitis condensans (Shoulder region)	0.004	0.996	0.000
M85.30 Osteitis condensans (Multiple sites)	0.004	0.996	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.004	0.996	0.000
M85.58 Aneurysmal bone cyst (Other)	0.004	0.996	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.004	0.996	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.004	0.996	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.004	0.996	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.004	0.996	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.004	0.996	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.004	0.996	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.004	0.996	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.004	0.996	0.000
T68 Hypothermia	0.000	0.996	0.004
M85.98 Disorder of bone density and structure, unspecified (Other)	0.004	0.996	0.000
Z61.9 Negative life events in childhood, unspecified	0.004	0.996	0.000
Z61.8 Other negative life events in childhood	0.004	0.996	0.000
Z61.7 Personal frightening experience in childhood	0.004	0.996	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.004	0.996	0.000
Z61.2 Altered pattern of family relationships in childhood	0.004	0.996	0.000
Z61.1 Removal from home in childhood	0.004	0.996	0.000
Z61.0 Loss of love relationship in childhood	0.004	0.996	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.004	0.996	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.004	0.996	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.004	0.996	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.004	0.996	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.004	0.996	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.004	0.996	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.004	0.996	0.000
Z58.1 Exposure to air pollution	0.004	0.996	0.000
T74 Maltreatment syndromes	0.000	0.996	0.004
T73 Effects of other deprivation	0.000	0.996	0.004
T69 Other effects of reduced temperature	0.000	0.996	0.004
T67 Effects of heat and light	0.000	0.996	0.004
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.004	0.996	0.000
Z56 Problems related to employment and unemployment	0.004	0.996	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.004	0.996	0.000
Z61.6 Problems related to alleged physical abuse of child	0.004	0.996	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.004	0.996	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.004	0.996	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.004	0.996	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.004	0.996	0.000
Z58.9 Problem related to physical environment, unspecified	0.004	0.996	0.000
Z58.7 Exposure to tobacco smoke	0.004	0.996	0.000
Z58.6 Inadequate drinking-water supply	0.004	0.996	0.000
Z58.4 Exposure to radiation	0.004	0.996	0.000
Z58.3 Exposure to soil pollution	0.004	0.996	0.000
Z58.2 Exposure to water pollution	0.004	0.996	0.000
Z58.0 Exposure to noise	0.004	0.996	0.000
M85.66 Other cyst of bone (Lower leg)	0.004	0.996	0.000
E85.4 Organ-limited amyloidosis	0.004	0.996	0.000
T71 Asphyxiation	0.000	0.996	0.004
Z65.3 Problems related to other legal circumstances	0.004	0.996	0.000
Z60.2 Living alone	0.004	0.996	0.000
J38.1 Polyp of vocal cord and larynx	0.004	0.996	0.000
Z57 Occupational exposure to risk-factors	0.004	0.996	0.000
M85.68 Other cyst of bone (Other)	0.004	0.996	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.004	0.996	0.000
M85.48 Solitary bone cyst (Other)	0.004	0.996	0.000
M85.44 Solitary bone cyst (Hand)	0.004	0.996	0.000
M85.43 Solitary bone cyst (Forearm)	0.004	0.996	0.000
M85.42 Solitary bone cyst (Upper arm)	0.004	0.996	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.004	0.996	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.004	0.996	0.000
D44.0 Thyroid gland	0.000	0.996	0.004
T70 Effects of air pressure and water pressure	0.000	0.996	0.004
M85.69 Other cyst of bone (Site unspecified)	0.004	0.996	0.000
M85.63 Other cyst of bone (Forearm)	0.004	0.996	0.000
M85.62 Other cyst of bone (Upper arm)	0.004	0.996	0.000
M85.61 Other cyst of bone (Shoulder region)	0.004	0.996	0.000
M85.60 Other cyst of bone (Multiple sites)	0.004	0.996	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.004	0.996	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.004	0.996	0.000
Z65.4 Victim of crime and terrorism	0.004	0.996	0.000
Z65.2 Problems related to release from prison	0.004	0.996	0.000
Z65.1 Imprisonment and other incarceration	0.004	0.996	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.004	0.996	0.000
Z56.3 Stressful work schedule	0.004	0.996	0.000
Z60.9 Problem related to social environment, unspecified	0.004	0.996	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.004	0.996	0.000
Z55.8 Other problems relating to education and literacy	0.004	0.996	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.004	0.996	0.000
Z55.3 Underachievement in school	0.004	0.996	0.000
Z55.2 Failed examinations	0.004	0.996	0.000
Z55.1 Schooling unavailable and unattainable	0.004	0.996	0.000
Z55.0 Illiteracy and low-level literacy	0.004	0.996	0.000
Z62.9 Problem related to upbringing, unspecified	0.004	0.996	0.000
Z62.8 Other specified problems related to upbringing	0.004	0.996	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.004	0.996	0.000
Z62.5 Other problems related to neglect in upbringing	0.004	0.996	0.000
Z62.4 Emotional neglect of child	0.004	0.996	0.000
Z62.3 Hostility towards and scapegoating of child	0.004	0.996	0.000
Z62.2 Institutional upbringing	0.004	0.996	0.000
Z62.1 Parental overprotection	0.004	0.996	0.000
Z62.0 Inadequate parental supervision and control	0.004	0.996	0.000
N99.0 Postprocedural renal failure	0.004	0.996	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.003	0.996	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.004	0.996	0.000
Z60.4 Social exclusion and rejection	0.004	0.996	0.000
Z60.3 Acculturation difficulty	0.004	0.996	0.000
Z60.1 Atypical parenting situation	0.004	0.996	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.004	0.996	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.004	0.996	0.000
Z58.5 Exposure to other pollution	0.003	0.996	0.000
M85.64 Other cyst of bone (Hand)	0.003	0.996	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.003	0.996	0.000
M85.46 Solitary bone cyst (Lower leg)	0.003	0.996	0.000
D06.9 Cervix, unspecified	0.004	0.996	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.003	0.996	0.000
T75 Effects of other external causes	0.000	0.996	0.003
I07.1 Tricuspid insufficiency	0.000	0.996	0.004
O75.8 Other specified complications of labour and delivery	0.000	0.996	0.004
Z64.4 Discord with counsellors	0.003	0.996	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.003	0.996	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.003	0.996	0.000
Z64.1 Problems related to multiparity	0.003	0.996	0.000
Z57.8 Occupational exposure to other risk-factors	0.003	0.996	0.000
J38.7 Other diseases of larynx	0.003	0.997	0.000
C62.9 Testis, unspecified	0.000	0.997	0.003
M07.34 Other psoriatic arthropathies (Hand)	0.003	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.003	0.997	0.000
T67.9 Effects of heat and light, unspecified	0.000	0.997	0.003
T67.8 Other effects of heat and light	0.000	0.997	0.003
T67.7 Heat oedema	0.000	0.997	0.003
T67.6 Heat fatigue, transient	0.000	0.997	0.003
T67.5 Heat exhaustion, unspecified	0.000	0.997	0.003
T67.4 Heat exhaustion due to salt depletion	0.000	0.997	0.003
T67.3 Heat exhaustion, anhydrotic	0.000	0.997	0.003
T67.2 Heat cramp	0.000	0.997	0.003
T67.1 Heat syncope	0.000	0.997	0.003
T67.0 Heatstroke and sunstroke	0.000	0.997	0.003
T69.9 Effect of reduced temperature, unspecified	0.000	0.997	0.003
T69.8 Other specified effects of reduced temperature	0.000	0.997	0.003
T69.1 Chilblains	0.000	0.997	0.003
T69.0 Immersion hand and foot	0.000	0.997	0.003
T73.9 Effect of deprivation, unspecified	0.000	0.997	0.003
T73.8 Other effects of deprivation	0.000	0.997	0.003
T73.3 Exhaustion due to excessive exertion	0.000	0.997	0.003
T73.2 Exhaustion due to exposure	0.000	0.997	0.003
T73.1 Effects of thirst	0.000	0.997	0.003
T73.0 Effects of hunger	0.000	0.997	0.003
T74.9 Maltreatment syndrome, unspecified	0.000	0.997	0.003
T74.8 Other maltreatment syndromes	0.000	0.997	0.003
T74.3 Psychological abuse	0.000	0.997	0.003
T74.2 Sexual abuse	0.000	0.997	0.003
T74.1 Physical abuse	0.000	0.997	0.003
T74.0 Neglect or abandonment	0.000	0.997	0.003
S69.7 Multiple injuries of wrist and hand	0.000	0.997	0.003
Z56.5 Uncongenial work	0.003	0.997	0.000
Z56.4 Discord with boss and workmates	0.003	0.997	0.000
Z56.2 Threat of job loss	0.003	0.997	0.000
Z56.1 Change of job	0.003	0.997	0.000
K82.8 Other specified diseases of gallbladder	0.000	0.997	0.003
M79.70 Fibromyalgia (Multiple sites)	0.003	0.997	0.000
D44.6 Carotid body	0.000	0.997	0.003
M85.65 Other cyst of bone (Pelvic region and thigh)	0.003	0.997	0.000
D44.3 Pituitary gland	0.000	0.997	0.003
Z60.8 Other problems related to social environment	0.003	0.997	0.000
J38.4 Oedema of larynx	0.003	0.997	0.000
Z56.7 Other and unspecified problems related to employment	0.003	0.997	0.000
D23.7 Skin of lower limb, including hip	0.003	0.997	0.000
Z64.0 Problems related to unwanted pregnancy	0.003	0.997	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.003	0.997	0.000
Z57.7 Occupational exposure to vibration	0.003	0.997	0.000
Z57.6 Occupational exposure to extreme temperature	0.003	0.997	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.003	0.997	0.000
Z57.1 Occupational exposure to radiation	0.003	0.997	0.000
Z57.0 Occupational exposure to noise	0.003	0.997	0.000
E83.5 Disorders of calcium metabolism	0.003	0.997	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.997	0.003
T70.8 Other effects of air pressure and water pressure	0.000	0.997	0.003
T70.4 Effects of high-pressure fluids	0.000	0.997	0.003
T70.2 Other and unspecified effects of high altitude	0.000	0.997	0.003
T70.1 Sinus barotrauma	0.000	0.997	0.003
T70.0 Otitic barotrauma	0.000	0.997	0.003
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.997	0.003
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.003	0.997	0.000
I97.1 Other functional disturbances following cardiac surgery	0.003	0.997	0.000
J38.3 Other diseases of vocal cords	0.003	0.997	0.000
J38.5 Laryngeal spasm	0.003	0.997	0.000
R57 Shock, not elsewhere classified	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
Z57.3 Occupational exposure to other air contaminants	0.003	0.997	0.000
D44.7 Aortic body and other paraganglia	0.000	0.997	0.003
J38.6 Stenosis of larynx	0.003	0.997	0.000
T75.8 Other specified effects of external causes	0.000	0.997	0.003
T75.3 Motion sickness	0.000	0.997	0.003
T75.2 Effects of vibration	0.000	0.997	0.003
T75.0 Effects of lightning	0.000	0.997	0.003
E85.9 Amyloidosis, unspecified	0.003	0.997	0.000
R57.0 Cardiogenic shock	0.003	0.997	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.003	0.997	0.000
Z57.2 Occupational exposure to dust	0.003	0.997	0.000
Z56.6 Other physical and mental strain related to work	0.002	0.997	0.000
E85 Amyloidosis	0.003	0.997	0.000
T70.3 Caisson disease [decompression sickness]	0.000	0.997	0.002
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
T75.1 Drowning and nonfatal submersion	0.000	0.997	0.002
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.003	0.997	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.002	0.997	0.000
R57.1 Hypovolaemic shock	0.002	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.997	0.003
Z56.0 Unemployment, unspecified	0.002	0.997	0.000
T75.4 Effects of electric current	0.000	0.997	0.002
D44.5 Pineal gland	0.000	0.997	0.002
D44.2 Parathyroid gland	0.000	0.997	0.002
K86.3 Pseudocyst of pancreas	0.002	0.997	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
D44.8 Pluriglandular involvement	0.000	0.998	0.002
J99.8 Respiratory disorders in other diseases classified elsewhere	0.002	0.998	0.000
R57.8 Other shock	0.002	0.998	0.000
H35.7 Separation of retinal layers	0.002	0.998	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
E85.8 Other amyloidosis	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.002	0.998	0.000
J38.2 Nodules of vocal cords	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.002	0.998	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.002	0.998	0.000
C81.1 Nodular sclerosis	0.000	0.998	0.002
M48.5 Collapsed vertebra, not elsewhere classified	0.002	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
D44.9 Endocrine gland, unspecified	0.000	0.998	0.002
D44.4 Craniopharyngeal duct	0.000	0.998	0.002
N28.1 Cyst of kidney, acquired	0.002	0.998	0.000
R57.9 Shock, unspecified	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.002	0.998	0.000
M79.2 Neuralgia and neuritis, unspecified	0.002	0.998	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.998	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.998	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.998	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.002	0.998	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.998	0.002
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.998	0.002
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.002	0.998	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.002	0.998	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.998	0.002
D44.1 Adrenal gland	0.000	0.998	0.002
D06 Carcinoma in situ of cervix uteri	0.002	0.998	0.000
F25 Schizoaffective disorders	0.002	0.998	0.000
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
D07.5 Prostate	0.002	0.998	0.000
K26.3 Acute without haemorrhage or perforation	0.000	0.998	0.002
R87.7 Abnormal histological findings	0.002	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.998	0.002
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.998	0.002
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
D06.0 Endocervix	0.002	0.998	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.002	0.998	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.002	0.998	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.998	0.002
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.998	0.002
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
J38.0 Paralysis of vocal cords and larynx	0.002	0.998	0.000
O75.3 Other infection during labour	0.000	0.998	0.002
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.998	0.002
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.002	0.998	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.002	0.998	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.002	0.998	0.000
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.002	0.998	0.000
J98.6 Disorders of diaphragm	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations