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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1024065
log Bayes Factor = 10.3744
Chromosome 1   position 222,761,601  (GRCh37) Explore rs1024065 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.001 0.999
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.002 0.998
I20.9 Angina pectoris, unspecified
0.000 0.003 0.997
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.005 0.995
I25.2 Old myocardial infarction
0.000 0.006 0.994
I22 Subsequent myocardial infarction
0.000 0.043 0.957
I20.0 Unstable angina
0.000 0.045 0.955
I21 Acute myocardial infarction
0.000 0.059 0.941
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.061 0.939
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.070 0.930
Chapter IX Diseases of the circulatory system
0.000 0.087 0.913
I05-I09 Chronic rheumatic heart diseases
0.000 0.109 0.891
I25.5 Ischaemic cardiomyopathy
0.000 0.122 0.878
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.123 0.877
I60-I69 Cerebrovascular diseases
0.000 0.124 0.876
I05 Rheumatic mitral valve diseases
0.000 0.153 0.847
I67 Other cerebrovascular diseases
0.000 0.154 0.846
I67.9 Cerebrovascular disease, unspecified
0.000 0.161 0.839
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.169 0.831
I60 Subarachnoid haemorrhage
0.000 0.195 0.805
I08 Multiple valve diseases
0.000 0.206 0.794
I10-I15 Hypertensive diseases
0.000 0.210 0.790
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.213 0.787
I12 Hypertensive renal disease
0.000 0.227 0.773
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.236 0.764
I12.0 Hypertensive renal disease with renal failure
0.000 0.243 0.757
I23 Certain current complications following acute myocardial infarction
0.000 0.245 0.755
I25.4 Coronary artery aneurysm
0.000 0.264 0.736
I05.0 Mitral stenosis
0.000 0.271 0.729
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I05.2 Mitral stenosis with insufficiency
0.000 0.284 0.716
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.286 0.714
I61 Intracerebral haemorrhage
0.000 0.291 0.709
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.293 0.707
I20.1 Angina pectoris with documented spasm
0.000 0.295 0.705
I60.8 Other subarachnoid haemorrhage
0.000 0.296 0.704
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.299 0.701
I09 Other rheumatic heart diseases
0.000 0.310 0.690
I69 Sequelae of cerebrovascular disease
0.000 0.314 0.686
I08.8 Other multiple valve diseases
0.000 0.317 0.683
I05.1 Rheumatic mitral insufficiency
0.000 0.319 0.681
I05.9 Mitral valve disease, unspecified
0.000 0.324 0.676
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.325 0.674
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.333 0.667
I77 Other disorders of arteries and arterioles
0.000 0.339 0.661
I07 Rheumatic tricuspid valve diseases
0.000 0.342 0.658
I00-I02 Acute rheumatic fever
0.000 0.345 0.655
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.372 0.628
I77.1 Stricture of artery
0.000 0.379 0.621
I22.8 Subsequent myocardial infarction of other sites
0.000 0.381 0.619
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.381 0.619
I12.9 Hypertensive renal disease without renal failure
0.000 0.386 0.613
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.390 0.610
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.391 0.609
I05.8 Other mitral valve diseases
0.000 0.393 0.607
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.393 0.606
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.393 0.606
I67.5 Moyamoya disease
0.000 0.393 0.606
I67.4 Hypertensive encephalopathy
0.000 0.393 0.606
I67.3 Progressive vascular leukoencephalopathy
0.000 0.393 0.606
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.397 0.603
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.400 0.600
I74 Arterial embolism and thrombosis
0.000 0.408 0.592
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.415 0.585
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.417 0.583
I23.8 Other current complications following acute myocardial infarction
0.000 0.420 0.580
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.423 0.577
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.423 0.577
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.426 0.574
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.427 0.573
I62 Other nontraumatic intracranial haemorrhage
0.000 0.429 0.571
I25.3 Aneurysm of heart
0.000 0.430 0.569
I08.9 Multiple valve disease, unspecified
0.000 0.431 0.569
I06 Rheumatic aortic valve diseases
0.000 0.433 0.567
I13 Hypertensive heart and renal disease
0.000 0.433 0.566
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.443 0.556
I09.9 Rheumatic heart disease, unspecified
0.000 0.453 0.547
I61.8 Other intracerebral haemorrhage
0.000 0.455 0.545
I74.5 Embolism and thrombosis of iliac artery
0.000 0.455 0.545
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.458 0.541
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.458 0.541
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.458 0.541
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.458 0.541
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.458 0.541
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.458 0.541
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.458 0.541
I11 Hypertensive heart disease
0.000 0.460 0.540
I70 Atherosclerosis
0.000 0.460 0.540
I20.8 Other forms of angina pectoris
0.000 0.465 0.535
I69.3 Sequelae of cerebral infarction
0.000 0.465 0.535
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.468 0.532
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.469 0.531
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.476 0.524
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.479 0.521
I77.8 Other specified disorders of arteries and arterioles
0.000 0.483 0.517
I08.0 Disorders of both mitral and aortic valves
0.000 0.486 0.514
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.489 0.511
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.492 0.508
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.498 0.501
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.504 0.495
I09.8 Other specified rheumatic heart diseases
0.000 0.505 0.495
I09.2 Chronic rheumatic pericarditis
0.000 0.505 0.495
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.505 0.495
I09.0 Rheumatic myocarditis
0.000 0.505 0.495
I07.1 Tricuspid insufficiency
0.000 0.509 0.491
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.512 0.488
I15 Secondary hypertension
0.000 0.519 0.481
I77.5 Necrosis of artery
0.000 0.526 0.474
I77.4 Coeliac artery compression syndrome
0.000 0.526 0.474
I77.3 Arterial fibromuscular dysplasia
0.000 0.526 0.474
I77.2 Rupture of artery
0.000 0.526 0.474
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.527 0.473
I07.9 Tricuspid valve disease, unspecified
0.000 0.528 0.472
I07.8 Other tricuspid valve diseases
0.000 0.528 0.472
I07.2 Tricuspid stenosis with insufficiency
0.000 0.528 0.472
I07.0 Tricuspid stenosis
0.000 0.528 0.472
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.529 0.471
I21.4 Acute subendocardial myocardial infarction
0.000 0.530 0.470
I67.8 Other specified cerebrovascular diseases
0.000 0.530 0.470
I02 Rheumatic chorea
0.000 0.530 0.469
I01 Rheumatic fever with heart involvement
0.000 0.530 0.469
I00 Rheumatic fever without mention of heart involvement
0.000 0.530 0.469
I67.1 Cerebral aneurysm, nonruptured
0.000 0.536 0.464
I63 Cerebral infarction
0.000 0.536 0.464
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.540 0.459
I50.1 Left ventricular failure
0.000 0.548 0.452
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.550 0.450
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.550 0.450
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.550 0.450
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.550 0.450
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.550 0.450
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.550 0.450
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.550 0.450
I30-I52 Other forms of heart disease
0.000 0.551 0.449
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.555 0.445
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.556 0.444
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.556 0.444
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.556 0.444
I50 Heart failure
0.000 0.558 0.442
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.559 0.441
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.561 0.439
I68.0 Cerebral amyloid angiopathy
0.000 0.565 0.435
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.568 0.432
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.569 0.431
I79.1 Aortitis in diseases classified elsewhere
0.000 0.569 0.431
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.569 0.431
I99 Other and unspecified disorders of circulatory system
0.000 0.570 0.430
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.575 0.425
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.575 0.425
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.575 0.425
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.576 0.424
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.579 0.421
I72 Other aneurysm
0.000 0.580 0.420
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.583 0.417
I51 Complications and ill-defined descriptions of heart disease
0.000 0.586 0.413
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.590 0.409
I62.1 Nontraumatic extradural haemorrhage
0.000 0.590 0.409
I51.9 Heart disease, unspecified
0.000 0.592 0.408
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.593 0.407
I06.8 Other rheumatic aortic valve diseases
0.000 0.593 0.407
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.593 0.407
I06.1 Rheumatic aortic insufficiency
0.000 0.593 0.407
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.594 0.406
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.594 0.406
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.594 0.406
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.594 0.406
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.596 0.404
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.601 0.399
I34 Nonrheumatic mitral valve disorders
0.000 0.602 0.398
I44 Atrioventricular and left bundle-branch block
0.000 0.611 0.389
I70.9 Generalised and unspecified atherosclerosis
0.000 0.613 0.387
I70.8 Atherosclerosis of other arteries
0.000 0.613 0.387
I51.8 Other ill-defined heart diseases
0.000 0.614 0.386
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.616 0.384
I77.0 Arteriovenous fistula, acquired
0.000 0.616 0.384
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.621 0.379
I70.0 Atherosclerosis of aorta
0.000 0.622 0.378
I34.1 Mitral (valve) prolapse
0.000 0.622 0.378
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.627 0.373
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.627 0.373
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.627 0.373
I65.1 Occlusion and stenosis of basilar artery
0.000 0.627 0.373
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.630 0.370
I70.1 Atherosclerosis of renal artery
0.000 0.633 0.367
I63.8 Other cerebral infarction
0.000 0.633 0.367
I77.6 Arteritis, unspecified
0.000 0.639 0.361
I78 Diseases of capillaries
0.000 0.642 0.358
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.643 0.357
I44.7 Left bundle-branch block, unspecified
0.000 0.644 0.356
I67.2 Cerebral atherosclerosis
0.000 0.648 0.352
I95 Hypotension
0.000 0.652 0.348
I74.8 Embolism and thrombosis of other arteries
0.000 0.652 0.347
I15.9 Seconday hypertension, unspecified
0.000 0.655 0.345
I15.8 Other secondary hypertension
0.000 0.655 0.345
I15.2 Hypertension secondary to endocrine disorders
0.000 0.655 0.345
I15.0 Renovascular hypertension
0.000 0.655 0.345
I44.2 Atrioventricular block, complete
0.000 0.656 0.344
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.658 0.342
I30 Acute pericarditis
0.000 0.662 0.338
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.663 0.337
I01.8 Other acute rheumatic heart disease
0.000 0.663 0.337
I01.2 Acute rheumatic myocarditis
0.000 0.663 0.337
I01.1 Acute rheumatic endocarditis
0.000 0.663 0.337
I01.0 Acute rheumatic pericarditis
0.000 0.663 0.337
I02.9 Rheumatic chorea without heart involvement
0.000 0.663 0.337
I02.0 Rheumatic chorea with heart involvement
0.000 0.663 0.337
I72.0 Aneurysm of carotid artery
0.000 0.664 0.336
I06.0 Rheumatic aortic stenosis
0.000 0.665 0.335
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.667 0.333
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.667 0.333
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.667 0.333
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.669 0.331
I52 Other heart disorders in diseases classified elsewhere
0.000 0.678 0.322
I48 Atrial fibrillation and flutter
0.000 0.678 0.322
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.678 0.322
I41 Myocarditis in diseases classified elsewhere
0.000 0.678 0.322
I40 Acute myocarditis
0.000 0.678 0.322
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.678 0.322
I32 Pericarditis in diseases classified elsewhere
0.000 0.678 0.322
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.679 0.321
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.679 0.321
I36 Nonrheumatic tricuspid valve disorders
0.000 0.680 0.320
I42 Cardiomyopathy
0.000 0.684 0.316
I44.3 Other and unspecified atrioventricular block
0.000 0.686 0.314
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.688 0.312
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.693 0.307
I33 Acute and subacute endocarditis
0.000 0.696 0.304
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.699 0.301
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.699 0.301
I72.1 Aneurysm of artery of upper extremity
0.000 0.699 0.301
I72.9 Aneurysm of unspecified site
0.000 0.699 0.301
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.701 0.299
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.701 0.298
I51.5 Myocardial degeneration
0.000 0.703 0.297
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.703 0.297
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.704 0.296
I72.8 Aneurysm of other specified arteries
0.000 0.705 0.295
I42.0 Dilated cardiomyopathy
0.000 0.705 0.295
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.706 0.294
I27 Other pulmonary heart diseases
0.000 0.706 0.294
I72.4 Aneurysm of artery of lower extremity
0.000 0.708 0.292
I73 Other peripheral vascular diseases
0.000 0.708 0.292
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.711 0.289
I28 Other diseases of pulmonary vessels
0.000 0.711 0.289
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.714 0.286
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.714 0.285
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.716 0.284
I44.4 Left anterior fascicular block
0.000 0.717 0.283
I72.3 Aneurysm of iliac artery
0.000 0.719 0.281
I51.6 Cardiovascular disease, unspecified
0.000 0.721 0.279
I44.5 Left posterior fascicular block
0.000 0.721 0.279
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.722 0.278
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.722 0.278
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.722 0.278
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.722 0.278
I95.0 Idiopathic hypotension
0.000 0.723 0.277
I37 Pulmonary valve disorders
0.000 0.724 0.276
I44.6 Other and unspecified fascicular block
0.000 0.726 0.274
I30.1 Infective pericarditis
0.000 0.726 0.274
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.728 0.272
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.729 0.271
I95.1 Orthostatic hypotension
0.000 0.736 0.264
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.736 0.263
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.737 0.262
I21.9 Acute myocardial infarction, unspecified
0.000 0.738 0.262
I15.1 Hypertension secondary to other renal disorders
0.000 0.740 0.259
I34.0 Mitral (valve) insufficiency
0.000 0.741 0.259
I78.9 Disease of capillaries, unspecified
0.000 0.743 0.256
I95.8 Other hypotension
0.000 0.746 0.254
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.748 0.252
I65.2 Occlusion and stenosis of carotid artery
0.000 0.754 0.246
I51.4 Myocarditis, unspecified
0.000 0.755 0.245
I42.9 Cardiomyopathy, unspecified
0.000 0.756 0.244
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.756 0.243
I30.8 Other forms of acute pericarditis
0.000 0.758 0.242
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.758 0.242
I50.9 Heart failure, unspecified
0.000 0.758 0.242
I71 Aortic aneurysm and dissection
0.000 0.759 0.241
I42.8 Other cardiomyopathies
0.000 0.759 0.241
I27.0 Primary pulmonary hypertension
0.000 0.768 0.232
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.769 0.231
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.769 0.231
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.769 0.231
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.769 0.231
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.769 0.231
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.769 0.231
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.769 0.231
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.769 0.231
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.769 0.231
I40.9 Acute myocarditis, unspecified
0.000 0.769 0.231
I40.8 Other acute myocarditis
0.000 0.769 0.231
I40.1 Isolated myocarditis
0.000 0.769 0.231
I40.0 Infective myocarditis
0.000 0.769 0.231
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.769 0.231
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.769 0.231
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.769 0.231
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.769 0.231
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.769 0.231
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.769 0.231
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.769 0.231
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.769 0.231
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.769 0.231
I48.4 Atypical atrial flutter
0.000 0.769 0.231
I48.3 Typical atrial flutter
0.000 0.769 0.231
I48.2 Chronic atrial fibrillation
0.000 0.769 0.231
I48.1 Persistent atrial fibrillation
0.000 0.769 0.231
I48.0 Paroxysmal atrial fibrillation
0.000 0.769 0.231
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.769 0.231
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.769 0.231
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.769 0.231
I73.8 Other specified peripheral vascular diseases
0.000 0.769 0.231
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.770 0.230
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.770 0.230
I98.0 Cardiovascular syphilis
0.000 0.770 0.230
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.771 0.229
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.771 0.229
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.771 0.229
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.771 0.229
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.773 0.227
I42.5 Other restrictive cardiomyopathy
0.000 0.773 0.227
I42.4 Endocardial fibroelastosis
0.000 0.773 0.227
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.773 0.227
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.773 0.227
I45 Other conduction disorders
0.000 0.774 0.226
I24 Other acute ischaemic heart diseases
0.000 0.775 0.225
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.776 0.224
I38 Endocarditis, valve unspecified
0.000 0.776 0.224
I95.2 Hypotension due to drugs
0.000 0.780 0.220
I27.9 Pulmonary heart disease, unspecified
0.000 0.780 0.220
I30.9 Acute pericarditis, unspecified
0.000 0.781 0.218
I33.9 Acute endocarditis, unspecified
0.000 0.782 0.218
I78.8 Other diseases of capillaries
0.000 0.783 0.217
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.785 0.214
I27.8 Other specified pulmonary heart diseases
0.000 0.786 0.214
I27.1 Kyphoscoliotic heart disease
0.000 0.789 0.211
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.791 0.209
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.792 0.207
I97.0 Postcardiotomy syndrome
0.000 0.792 0.207
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.793 0.207
I28.1 Aneurysm of pulmonary artery
0.000 0.793 0.207
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.793 0.207
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.795 0.205
I26 Pulmonary embolism
0.000 0.796 0.204
I72.2 Aneurysm of renal artery
0.001 0.799 0.201
I33.0 Acute and subacute infective endocarditis
0.000 0.800 0.199
I45.5 Other specified heart block
0.000 0.802 0.198
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.802 0.198
I37.9 Pulmonary valve disorder, unspecified
0.000 0.802 0.198
I37.8 Other pulmonary valve disorders
0.000 0.802 0.198
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.802 0.198
I37.0 Pulmonary valve stenosis
0.000 0.802 0.198
I44.0 Atrioventricular block, first degree
0.000 0.811 0.189
I95.9 Hypotension, unspecified
0.000 0.819 0.181
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.820 0.180
I28.8 Other specified diseases of pulmonary vessels
0.000 0.820 0.180
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.820 0.180
I42.6 Alcoholic cardiomyopathy
0.000 0.821 0.179
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.821 0.179
I45.2 Bifascicular block
0.000 0.825 0.175
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.827 0.173
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.827 0.173
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.827 0.173
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.827 0.173
I45.4 Nonspecific intraventricular block
0.000 0.828 0.172
I51.0 Cardiac septal defect, acquired
0.001 0.829 0.171
I24.1 Dressler's syndrome
0.000 0.830 0.170
I97.1 Other functional disturbances following cardiac surgery
0.000 0.835 0.164
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.837 0.163
I45.0 Right fascicular block
0.000 0.837 0.162
I45.3 Trifascicular block
0.000 0.839 0.161
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.845 0.155
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.846 0.154
I37.1 Pulmonary valve insufficiency
0.000 0.849 0.151
I73.0 Raynaud's syndrome
0.000 0.853 0.147
I86 Varicose veins of other sites
0.000 0.855 0.145
I46 Cardiac arrest
0.000 0.855 0.145
I35 Nonrheumatic aortic valve disorders
0.000 0.856 0.144
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.862 0.138
I45.8 Other specified conduction disorders
0.000 0.864 0.136
I86.4 Gastric varices
0.000 0.869 0.131
I82 Other venous embolism and thrombosis
0.000 0.869 0.131
I27.2 Other secondary pulmonary hypertension
0.000 0.870 0.129
I45.9 Conduction disorder, unspecified
0.000 0.873 0.127
I85 Oesophageal varices
0.000 0.877 0.123
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.883 0.116
I42.2 Other hypertrophic cardiomyopathy
0.001 0.886 0.113
I31 Other diseases of pericardium
0.001 0.888 0.111
I86.1 Scrotal varices
0.000 0.889 0.111
I78.1 Naevus, nonneoplastic
0.000 0.891 0.109
I88 Nonspecific lymphadenitis
0.000 0.892 0.108
I82.8 Embolism and thrombosis of other specified veins
0.000 0.893 0.107
I81 Portal vein thrombosis
0.000 0.895 0.105
I45.6 Preexcitation syndrome
0.000 0.895 0.105
I44.1 Atrioventricular block, second degree
0.000 0.895 0.104
I45.1 Other and unspecified right bundle-branch block
0.000 0.895 0.105
I80 Phlebitis and thrombophlebitis
0.000 0.895 0.104
I86.3 Vulval varices
0.000 0.896 0.104
I86.2 Pelvic varices
0.000 0.896 0.104
I86.0 Sublingual varices
0.000 0.896 0.104
I46.1 Sudden cardiac death, so described
0.000 0.896 0.104
I86.8 Varicose veins of other specified sites
0.000 0.896 0.103
I35.0 Aortic (valve) stenosis
0.000 0.896 0.104
I63.9 Cerebral infarction, unspecified
0.000 0.897 0.103
I87 Other disorders of veins
0.000 0.898 0.102
I82.2 Embolism and thrombosis of vena cava
0.000 0.898 0.101
I71.0 Dissection of aorta [any part]
0.000 0.899 0.101
I35.9 Aortic valve disorder, unspecified
0.000 0.900 0.100
I24.8 Other forms of acute ischaemic heart disease
0.000 0.904 0.096
I82.1 Thrombophlebitis migrans
0.000 0.906 0.094
I82.0 Budd-Chiari syndrome
0.000 0.906 0.094
I85.0 Oesophageal varices with bleeding
0.000 0.907 0.093
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.908 0.092
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.908 0.092
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.910 0.090
I85.9 Oesophageal varices without bleeding
0.000 0.911 0.089
I82.3 Embolism and thrombosis of renal vein
0.000 0.912 0.087
I35.1 Aortic (valve) insufficiency
0.000 0.913 0.087
I35.8 Other aortic valve disorders
0.000 0.913 0.087
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.914 0.086
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.915 0.085
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.917 0.082
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.918 0.082
I31.8 Other specified diseases of pericardium
0.001 0.919 0.080
I31.2 Haemopericardium, not elsewhere classified
0.001 0.919 0.080
I31.1 Chronic constrictive pericarditis
0.001 0.919 0.080
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.922 0.077
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.922 0.077
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.923 0.077
I31.0 Chronic adhesive pericarditis
0.001 0.923 0.076
I87.9 Disorder of vein, unspecified
0.000 0.927 0.073
I87.0 Postphlebitic syndrome
0.000 0.927 0.073
I88.8 Other nonspecific lymphadenitis
0.000 0.931 0.069
I87.1 Compression of vein
0.000 0.935 0.065
I47 Paroxysmal tachycardia
0.000 0.937 0.063
I73.9 Peripheral vascular disease, unspecified
0.000 0.939 0.061
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.941 0.059
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.942 0.058
I46.0 Cardiac arrest with successful resuscitation
0.000 0.943 0.057
I87.8 Other specified disorders of veins
0.000 0.947 0.053
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.948 0.051
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.951 0.049
I83 Varicose veins of lower extremities
0.000 0.952 0.048
I10 Essential (primary) hypertension
0.000 0.955 0.045
I46.9 Cardiac arrest, unspecified
0.000 0.956 0.044
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.956 0.044
I31.3 Pericardial effusion (noninflammatory)
0.000 0.959 0.041
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.959 0.041
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.961 0.039
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.962 0.037
I49 Other cardiac arrhythmias
0.000 0.963 0.037
I47.0 Reentry ventricular arrhythmia
0.000 0.965 0.035
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.968 0.032
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.968 0.032
I89.0 Lymphoedema, not elsewhere classified
0.000 0.969 0.031
I50.0 Congestive heart failure
0.000 0.969 0.031
I89.1 Lymphangitis
0.000 0.972 0.028
I49.4 Other and unspecified premature depolarisation
0.000 0.972 0.028
I49.2 Junctional premature depolarisation
0.000 0.973 0.027
I49.0 Ventricular fibrillation and flutter
0.000 0.973 0.027
I49.3 Ventricular premature depolarisation
0.000 0.977 0.023
I47.2 Ventricular tachycardia
0.000 0.978 0.022
E78.0 Pure hypercholesterolaemia
0.000 0.980 0.020
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.983 0.017
Z95.1 Presence of aortocoronary bypass graft
0.000 0.984 0.016
I31.9 Disease of pericardium, unspecified
0.001 0.984 0.015
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.984 0.016
I49.8 Other specified cardiac arrhythmias
0.000 0.984 0.016
I49.9 Cardiac arrhythmia, unspecified
0.000 0.985 0.015
I49.1 Atrial premature depolarisation
0.000 0.985 0.015
I51.7 Cardiomegaly
0.000 0.986 0.014
Z95.4 Presence of other heart-valve replacement
0.000 0.986 0.014
Z95.0 Presence of cardiac pacemaker
0.000 0.986 0.014
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.986 0.013
I49.5 Sick sinus syndrome
0.000 0.986 0.013
Z95.2 Presence of prosthetic heart valve
0.000 0.987 0.013
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.000 0.989 0.011
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.989 0.011
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.990 0.010
Z95.3 Presence of xenogenic heart valve
0.000 0.990 0.010
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.990 0.010
B18.2 Chronic viral hepatitis C
0.010 0.990 0.000
I47.1 Supraventricular tachycardia
0.000 0.991 0.009
B18 Chronic viral hepatitis
0.008 0.992 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.008 0.992 0.000
R07.4 Chest pain, unspecified
0.000 0.992 0.008
D13.2 Duodenum
0.000 0.992 0.008
B18.9 Chronic viral hepatitis, unspecified
0.006 0.994 0.000
B18.8 Other chronic viral hepatitis
0.006 0.994 0.000
B18.0 Chronic viral hepatitis B with delta-agent
0.006 0.994 0.000
B15-B19 Viral hepatitis
0.006 0.994 0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma
0.005 0.994 0.000
B16 Acute hepatitis B
0.005 0.994 0.000
K51.4 Pseudopolyposis of colon
0.005 0.995 0.000
R07.2 Precordial pain
0.000 0.995 0.005
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.995 0.005
B15 Acute hepatitis A
0.005 0.995 0.000
B17 Other acute viral hepatitis
0.004 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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