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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1028411
log Bayes Factor = 49.3084
Chromosome 6   position 29,367,399  (GRCh37) Explore rs1028411 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E20-E35 Disorders of other endocrine glands
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.002 0.998
E27 Other disorders of adrenal gland
0.000 0.006 0.994
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.006 0.994
E10.2 With renal complications
0.000 0.010 0.990
E27.1 Primary adrenocortical insufficiency
0.000 0.016 0.984
E14 Unspecified diabetes mellitus
0.000 0.031 0.969
E10.4 With neurological complications
0.000 0.042 0.958
E13 Other specified diabetes mellitus
0.000 0.042 0.958
L40.9 Psoriasis, unspecified
0.956 0.044 0.000
E10.1 With ketoacidosis
0.000 0.053 0.947
E14.3 With ophthalmic complications
0.000 0.066 0.934
E24 Cushing's syndrome
0.000 0.071 0.929
E13.9 Without complications
0.000 0.072 0.928
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.087 0.913
E23 Hypofunction and other disorders of pituitary gland
0.000 0.091 0.909
E20 Hypoparathyroidism
0.000 0.095 0.905
E50-E64 Other nutritional deficiencies
0.000 0.144 0.856
E23.0 Hypopituitarism
0.000 0.157 0.843
E20.9 Hypoparathyroidism, unspecified
0.000 0.162 0.838
E24.0 Pituitary-dependent Cushing's disease
0.000 0.172 0.828
E05.8 Other thyrotoxicosis
0.000 0.175 0.825
E14.6 With other specified complications
0.000 0.185 0.815
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.202 0.798
E03 Other hypothyroidism
0.000 0.213 0.787
E22 Hyperfunction of pituitary gland
0.000 0.215 0.785
E24.9 Cushing's syndrome, unspecified
0.000 0.224 0.776
E29 Testicular dysfunction
0.000 0.229 0.771
E14.2 Withrenal complications
0.000 0.236 0.764
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.242 0.757
E10.7 With multiple complications
0.000 0.251 0.749
E10.0 With coma
0.000 0.254 0.746
E55 Vitamin D deficiency
0.000 0.266 0.734
E23.2 Diabetes insipidus
0.000 0.269 0.731
E53 Deficiency of other B group vitamins
0.000 0.273 0.727
E14.5 With peripheral circulatory complications
0.000 0.277 0.723
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.280 0.720
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.284 0.716
E32 Diseases of thymus
0.000 0.284 0.716
E30 Disorders of puberty, not elsewhere classified
0.000 0.284 0.716
E14.8 With unspecified complications
0.000 0.286 0.713
E27.5 Adrenomedullary hyperfunction
0.000 0.287 0.713
E27.0 Other adrenocortical overactivity
0.000 0.287 0.713
E51 Thiamine deficiency
0.000 0.287 0.713
E25 Adrenogenital disorders
0.000 0.292 0.708
E24.2 Drug-induced Cushing's syndrome
0.000 0.299 0.701
E10.8 With unspecified complications
0.000 0.300 0.700
E10.6 With other specified complications
0.000 0.302 0.697
E53.9 Vitamin B deficiency, unspecified
0.000 0.305 0.695
E14.7 With multiple complications
0.000 0.305 0.695
E14.0 With coma
0.000 0.305 0.695
E27.8 Other specified disorders of adrenal gland
0.000 0.306 0.694
E13.3 With ophthalmic complications
0.000 0.311 0.689
E40-E46 Malnutrition
0.000 0.312 0.688
E13.8 With unspecified complications
0.000 0.313 0.687
E13.7 With multiple complications
0.000 0.313 0.687
E13.6 With other specified complications
0.000 0.313 0.687
E13.5 With peripheral circulatory complications
0.000 0.313 0.687
E13.4 With neurological complications
0.000 0.313 0.687
E13.2 With renal complications
0.000 0.313 0.687
E13.1 With ketoacidosis
0.000 0.313 0.687
E13.0 With coma
0.000 0.313 0.687
E31 Polyglandular dysfunction
0.000 0.316 0.684
E14.1 With ketoacidosis
0.000 0.317 0.683
E22.0 Acromegaly and pituitary gigantism
0.000 0.323 0.677
L40 Psoriasis
0.673 0.327 0.000
E28 Ovarian dysfunction
0.000 0.328 0.672
E24.8 Other Cushing's syndrome
0.000 0.334 0.666
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.334 0.666
E24.3 Ectopic ACTH syndrome
0.000 0.334 0.666
E24.1 Nelson's syndrome
0.000 0.334 0.666
E10.5 With peripheral circulatory complications
0.000 0.336 0.664
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.349 0.651
E23.1 Drug-induced hypopituitarism
0.000 0.349 0.651
E20.8 Other hypoparathyroidism
0.000 0.351 0.649
E20.1 Pseudohypoparathyroidism
0.000 0.351 0.649
E20.0 Idiopathic hypoparathyroidism
0.000 0.351 0.649
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.353 0.647
E55.9 Vitamin D deficiency, unspecified
0.000 0.353 0.647
E27.9 Disorder of adrenal gland, unspecified
0.000 0.359 0.641
E23.7 Disorder of pituitary gland, unspecified
0.000 0.362 0.638
E14.4 With neurological complications
0.000 0.370 0.630
E03.9 Hypothyroidism, unspecified
0.000 0.372 0.628
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.386 0.614
E50 Vitamin A deficiency
0.000 0.386 0.614
E60 Dietary zinc deficiency
0.000 0.386 0.614
E59 Dietary selenium deficiency
0.000 0.386 0.614
E52 Niacin deficiency [pellagra]
0.000 0.386 0.614
E51.2 Wernicke's encephalopathy
0.000 0.390 0.610
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.390 0.609
E29.1 Testicular hypofunction
0.000 0.392 0.608
K90 Intestinal malabsorption
0.000 0.394 0.606
E07 Other disorders of thyroid
0.000 0.394 0.606
E27.2 Addisonian crisis
0.000 0.395 0.604
E22.1 Hyperprolactinaemia
0.000 0.401 0.599
E61 Deficiency of other nutrient elements
0.000 0.405 0.595
E34 Other endocrine disorders
0.000 0.411 0.589
E26 Hyperaldosteronism
0.000 0.411 0.589
E14.9 Without complications
0.000 0.413 0.587
E03.1 Congenital hypothyroidism without goitre
0.000 0.416 0.584
E56 Other vitamin deficiencies
0.000 0.424 0.576
E58 Dietary calcium deficiency
0.000 0.425 0.575
E03.5 Myxoedema coma
0.000 0.436 0.564
E03.4 Atrophy of thyroid (acquired)
0.000 0.436 0.564
E03.3 Postinfectious hypothyroidism
0.000 0.436 0.564
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.437 0.563
E22.8 Other hyperfunction of pituitary gland
0.000 0.437 0.563
L40.5 Arthropathic psoriasis
0.562 0.438 0.000
E23.6 Other disorders of pituitary gland
0.000 0.444 0.556
E29.9 Testicular dysfunction, unspecified
0.000 0.447 0.553
E29.8 Other testicular dysfunction
0.000 0.447 0.553
E29.0 Testicular hyperfunction
0.000 0.447 0.553
L40.8 Other psoriasis
0.551 0.449 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.449 0.551
E06 Thyroiditis
0.000 0.457 0.543
E63 Other nutritional deficiencies
0.000 0.470 0.530
E55.0 Rickets, active
0.000 0.474 0.526
L40.0 Psoriasis vulgaris
0.526 0.474 0.000
E54 Ascorbic acid deficiency
0.000 0.475 0.525
E53.1 Pyridoxine deficiency
0.000 0.479 0.521
E53.0 Riboflavin deficiency
0.000 0.479 0.521
E16 Other disorders of pancreatic internal secretion
0.000 0.481 0.519
E15 Nondiabetic hypoglycaemic coma
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.513
E30.8 Other disorders of puberty
0.000 0.486 0.513
E30.1 Precocious puberty
0.000 0.486 0.513
E30.0 Delayed puberty
0.000 0.486 0.513
E32.9 Disease of thymus, unspecified
0.000 0.486 0.513
E32.8 Other diseases of thymus
0.000 0.486 0.513
E32.1 Abscess of thymus
0.000 0.486 0.513
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.513
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.513
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.513
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.513
E51.9 Thiamine deficiency, unspecified
0.000 0.489 0.511
E51.8 Other manifestations of thiamine deficiency
0.000 0.489 0.511
E51.1 Beriberi
0.000 0.489 0.511
E03.8 Other specified hypothyroidism
0.000 0.492 0.508
E25.9 Adrenogenital disorder, unspecified
0.000 0.492 0.508
E25.8 Other adrenogenital disorders
0.000 0.492 0.508
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.500 0.500
K90.9 Intestinal malabsorption, unspecified
0.000 0.502 0.498
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.506 0.494
E45 Retarded development following protein-energy malnutrition
0.000 0.506 0.494
E43 Unspecified severe protein-energy malnutrition
0.000 0.506 0.494
E42 Marasmic kwashiorkor
0.000 0.506 0.494
E41 Nutritional marasmus
0.000 0.506 0.494
E40 Kwashiorkor
0.000 0.506 0.494
E31.9 Polyglandular dysfunction, unspecified
0.000 0.509 0.490
E31.8 Other polyglandular dysfunction
0.000 0.509 0.490
E31.1 Polyglandular hyperfunction
0.000 0.509 0.490
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.512 0.488
L40.2 Acrodermatitis continua
0.482 0.517 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.518 0.482
E28.8 Other ovarian dysfunction
0.000 0.518 0.482
E28.1 Androgen excess
0.000 0.518 0.482
E28.0 Oestrogen excess
0.000 0.518 0.482
E28.2 Polycystic ovarian syndrome
0.000 0.518 0.481
L40.4 Guttate psoriasis
0.481 0.519 0.000
L40.3 Pustulosis palmaris et plantaris
0.468 0.532 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.535 0.465
E31.0 Autoimmune polyglandular failure
0.000 0.541 0.458
L40.1 Generalised pustular psoriasis
0.452 0.548 0.000
E61.2 Magnesium deficiency
0.000 0.558 0.442
E26.9 Hyperaldosteronism, unspecified
0.000 0.560 0.440
E50.9 Vitamin A deficiency, unspecified
0.000 0.560 0.440
E50.8 Other manifestations of vitamin A deficiency
0.000 0.560 0.440
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.560 0.440
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.560 0.440
E50.5 Vitamin A deficiency with night blindness
0.000 0.560 0.440
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.560 0.440
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.560 0.440
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.560 0.440
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.560 0.440
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.560 0.440
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.560 0.440
E64.8 Sequelae of other nutritional deficiencies
0.000 0.560 0.440
E64.3 Sequelae of rickets
0.000 0.560 0.440
E64.2 Sequelae of vitamin C deficiency
0.000 0.560 0.440
E64.1 Sequelae of vitamin A deficiency
0.000 0.560 0.440
E64.0 Sequelae of protein-energy malnutrition
0.000 0.560 0.440
E28.3 Primary ovarian failure
0.000 0.561 0.439
K90.3 Pancreatic steatorrhoea
0.000 0.565 0.435
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.565 0.435
K90.1 Tropical sprue
0.000 0.565 0.435
E07.1 Dyshormogenetic goitre
0.000 0.565 0.435
E07.0 Hypersecretion of calcitonin
0.000 0.565 0.435
E34.3 Short stature, not elsewhere classified
0.000 0.569 0.431
E61.9 Deficiency of nutrient element, unspecified
0.000 0.574 0.426
E61.8 Deficiency of other specified nutrient elements
0.000 0.574 0.426
E61.7 Deficiency of multiple nutrient elements
0.000 0.574 0.426
E61.6 Vanadium deficiency
0.000 0.574 0.426
E61.5 Molybdenum deficiency
0.000 0.574 0.426
E61.4 Chromium deficiency
0.000 0.574 0.426
E61.3 Manganese deficiency
0.000 0.574 0.426
E61.0 Copper deficiency
0.000 0.574 0.426
E34.5 Androgen resistance syndrome
0.000 0.577 0.423
E34.4 Constitutional tall stature
0.000 0.577 0.423
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.577 0.423
E34.1 Other hypersecretion of intestinal hormones
0.000 0.577 0.423
E26.8 Other hyperaldosteronism
0.000 0.577 0.422
E26.1 Secondary hyperaldosteronism
0.000 0.577 0.422
E07.9 Disorder of thyroid, unspecified
0.000 0.580 0.420
E56.9 Vitamin deficiency, unspecified
0.000 0.587 0.413
E56.8 Deficiency of other vitamins
0.000 0.587 0.413
E56.0 Deficiency of vitamin E
0.000 0.587 0.413
K90.8 Other intestinal malabsorption
0.000 0.589 0.411
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.593 0.407
E16.1 Other hypoglycaemia
0.000 0.593 0.407
E34.9 Endocrine disorder, unspecified
0.000 0.599 0.401
E34.8 Other specified endocrine disorders
0.000 0.603 0.396
E06.4 Drug-induced thyroiditis
0.000 0.610 0.389
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.610 0.389
E06.1 Subacute thyroiditis
0.000 0.610 0.389
E06.0 Acute thyroiditis
0.000 0.610 0.389
E61.1 Iron deficiency
0.000 0.612 0.388
E06.9 Thyroiditis, unspecified
0.000 0.617 0.383
E63.8 Other specified nutritional deficiencies
0.000 0.619 0.380
E63.1 Imbalance of constituents of food intake
0.000 0.619 0.380
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.619 0.380
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.622 0.377
E56.1 Deficiency of vitamin K
0.000 0.624 0.375
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.628 0.372
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.628 0.372
E16.4 Abnormal secretion of gastrin
0.000 0.628 0.372
E16.3 Increased secretion of glucagon
0.000 0.628 0.372
E44.1 Mild protein-energy malnutrition
0.000 0.646 0.354
E44.0 Moderate protein-energy malnutrition
0.000 0.646 0.354
E34.0 Carcinoid syndrome
0.000 0.647 0.353
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.647 0.352
E16.2 Hypoglycaemia, unspecified
0.000 0.648 0.352
E07.8 Other specified disorders of thyroid
0.000 0.652 0.347
E06.3 Autoimmune thyroiditis
0.000 0.673 0.327
E06.5 Other chronic thyroiditis
0.000 0.680 0.320
E63.9 Nutritional deficiency, unspecified
0.001 0.703 0.296
E65-E68 Obesity and other hyperalimentation
0.000 0.738 0.262
E26.0 Primary hyperaldosteronism
0.001 0.740 0.259
E67 Other hyperalimentation
0.000 0.812 0.188
E68 Sequelae of hyperalimentation
0.000 0.812 0.188
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.814 0.186
E04 Other non-toxic goitre
0.001 0.864 0.135
E67.8 Other specified hyperalimentation
0.000 0.865 0.135
E67.3 Hypervitaminosis D
0.000 0.865 0.135
E67.2 Megavitamin-B6 syndrome
0.000 0.865 0.135
E67.1 Hypercarotenaemia
0.000 0.865 0.135
E67.0 Hypervitaminosis A
0.000 0.865 0.135
E21.4 Other specified disorders of parathyroid gland
0.000 0.867 0.133
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.870 0.130
E53.8 Deficiency of other specified B group vitamins
0.000 0.871 0.129
E21.2 Other hyperparathyroidism
0.000 0.872 0.128
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.883 0.116
L40-L45 Papulosquamous disorders
0.108 0.892 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.894 0.106
E04.8 Other specified non-toxic goitre
0.001 0.902 0.097
E65 Localised adiposity
0.001 0.902 0.097
M35.0 Sicca syndrome [Sjogren]
0.000 0.906 0.094
L44 Other papulosquamous disorders
0.078 0.922 0.000
L41 Parapsoriasis
0.078 0.922 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.078 0.922 0.000
E83 Disorders of mineral metabolism
0.071 0.929 0.000
L42 Pityriasis rosea
0.061 0.939 0.001
E04.0 Non-toxic diffuse goitre
0.002 0.940 0.058
L41.9 Parapsoriasis, unspecified
0.056 0.944 0.000
L41.8 Other parapsoriasis
0.056 0.944 0.000
L41.5 Retiform parapsoriasis
0.056 0.944 0.000
L41.4 Large plaque parapsoriasis
0.056 0.944 0.000
L41.3 Small plaque parapsoriasis
0.056 0.944 0.000
L41.2 Lymphomatoid papulosis
0.056 0.944 0.000
L41.1 Pityriasis lichenoides chronica
0.056 0.944 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.056 0.944 0.000
L44.9 Papulosquamous disorder, unspecified
0.056 0.944 0.000
L44.8 Other specified papulosquamous disorders
0.056 0.944 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.056 0.944 0.000
L44.3 Lichen ruber moniliformis
0.056 0.944 0.000
L44.2 Lichen striatus
0.056 0.944 0.000
L44.1 Lichen nitidus
0.056 0.944 0.000
L44.0 Pityriasis rubra pilaris
0.056 0.944 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.945 0.055
E83.8 Other disorders of mineral metabolism
0.051 0.949 0.000
E83.2 Disorders of zinc metabolism
0.051 0.949 0.000
E83.0 Disorders of copper metabolism
0.051 0.949 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.050 0.949 0.000
E83.3 Disorders of phosphorus metabolism
0.045 0.955 0.000
K90-K93 Other diseases of the digestive system
0.001 0.961 0.039
E11 Non-insulin-dependent diabetes mellitus
0.000 0.962 0.038
E21.0 Primary hyperparathyroidism
0.000 0.966 0.034
L43 Lichen planus
0.033 0.966 0.001
E11.6 With other specified complications
0.000 0.970 0.030
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.972 0.028
E11.2 With renal complications
0.000 0.972 0.028
E11.7 With multiple complications
0.000 0.972 0.028
E11.9 Without complications
0.000 0.974 0.026
L43.3 Subacute (active) lichen planus
0.024 0.975 0.001
L43.2 Lichenoid drug reaction
0.024 0.975 0.001
L43.1 Bullous lichen planus
0.024 0.975 0.001
L43.0 Hypertrophic lichen planus
0.024 0.975 0.001
E66 Obesity
0.000 0.976 0.023
E11.8 With unspecified complications
0.000 0.977 0.023
E11.0 With coma
0.000 0.978 0.022
E83.4 Disorders of magnesium metabolism
0.021 0.979 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.979 0.020
K93.1 Megacolon in Chagas' disease
0.001 0.979 0.020
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.979 0.020
H90 Conductive and sensorineural hearing loss
0.000 0.982 0.018
L43.8 Other lichen planus
0.017 0.982 0.001
H90.2 Conductive hearing loss, unspecified
0.000 0.983 0.017
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.000 0.983 0.017
H90.3 Sensorineural hearing loss, bilateral
0.000 0.983 0.017
E66.1 Drug-induced obesity
0.000 0.983 0.017
E11.1 With ketoacidosis
0.000 0.983 0.017
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.000 0.984 0.016
E66.0 Obesity due to excess calories
0.000 0.984 0.016
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.984 0.016
A08.4 Viral intestinal infection, unspecified
0.000 0.985 0.015
H90.5 Sensorineural hearing loss, unspecified
0.000 0.985 0.015
E11.5 With peripheral circulatory complications
0.000 0.985 0.015
E04.2 Non-toxic multinodular goitre
0.001 0.986 0.012
E83.5 Disorders of calcium metabolism
0.013 0.987 0.000
M35 Other systemic involvement of connective tissue
0.000 0.987 0.013
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.987 0.013
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.012 0.988 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.000 0.989 0.011
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.989 0.011
E04.1 Non-toxic single thyroid nodule
0.003 0.990 0.007
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.990 0.009
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.990 0.009
M35.5 Multifocal fibrosclerosis
0.000 0.990 0.009
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.990 0.009
M35.2 Behcet's disease
0.000 0.990 0.009
M35.8 Other specified systemic involvement of connective tissue
0.000 0.991 0.009
K51.4 Pseudopolyposis of colon
0.009 0.991 0.000
C50.3 Lower-inner quadrant of breast
0.000 0.991 0.009
H90.0 Conductive hearing loss, bilateral
0.000 0.991 0.009
M35.1 Other overlap syndromes
0.000 0.991 0.009
K51 Ulcerative colitis
0.008 0.992 0.000
K51.2 Ulcerative (chronic) proctitis
0.008 0.992 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.008 0.992 0.000
E11.4 With neurological complications
0.000 0.992 0.008
K92.0 Haematemesis
0.008 0.992 0.000
M35.7 Hypermobility syndrome
0.000 0.992 0.007
K92 Other diseases of digestive system
0.005 0.993 0.002
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.993 0.007
A08 Viral and other specified intestinal infections
0.000 0.993 0.007
K51.5 Mucosal proctocolitis
0.007 0.993 0.000
K92.1 Melaena
0.006 0.994 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.006 0.994 0.000
E11.3 With ophthalmic complications
0.000 0.994 0.006
A08.3 Other viral enteritis
0.000 0.994 0.006
K51.1 Ulcerative (chronic) ileocolitis
0.006 0.994 0.000
K92.8 Other specified diseases of digestive system
0.005 0.994 0.001
B97 Viral agents as the cause of diseases classified to other chapters
0.006 0.994 0.000
X41.9 Unspecified place
0.006 0.994 0.000
A08.5 Other specified intestinal infections
0.000 0.995 0.005
A08.2 Adenoviral enteritis
0.000 0.995 0.005
A08.0 Rotaviral enteritis
0.000 0.995 0.005
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.005 0.995 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.000 0.995 0.005
A87.9 Viral meningitis, unspecified
0.000 0.995 0.005
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.004 0.995 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.004 0.995 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.004 0.995 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.004 0.995 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.004 0.995 0.000
M65.34 Trigger finger-Hand
0.000 0.995 0.005
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.004 0.995 0.000
K51.8 Other ulcerative colitis
0.004 0.996 0.000
M22.2 Patellofemoral disorders
0.000 0.996 0.004
K51.9 Ulcerative colitis, unspecified
0.004 0.996 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.004 0.996 0.000
S82.10 Fracture of upper end of tibia (closed)
0.000 0.996 0.004
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.996 0.004
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.996 0.004
M34.1 CR(E)ST syndrome
0.000 0.996 0.004
H26.9 Cataract, unspecified
0.000 0.996 0.004
C77.4 Inguinal and lower limb lymph nodes
0.000 0.996 0.004
L43.9 Lichen planus, unspecified
0.002 0.996 0.002
S52.60 Fracture of lower end of both ulna and radius (closed)
0.000 0.996 0.004
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.004 0.996 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.996 0.004
D47.4 Osteomyelofibrosis
0.000 0.996 0.004
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.996 0.003
M34 Systemic sclerosis
0.000 0.997 0.003
L53.9 Erythematous condition, unspecified
0.003 0.997 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.003 0.997 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.997 0.003
M34.9 Systemic sclerosis, unspecified
0.000 0.997 0.003
E70-E90 Metabolic disorders
0.001 0.997 0.003
M34.8 Other forms of systemic sclerosis
0.000 0.997 0.003
D47.2 Monoclonal gammopathy
0.000 0.997 0.003
C50.1 Central portion of breast
0.000 0.997 0.003
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.997 0.003
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.997 0.003
K91.1 Postgastric surgery syndromes
0.000 0.997 0.003
K92.9 Disease of digestive system, unspecified
0.001 0.997 0.002
M31.6 Other giant cell arteritis
0.000 0.997 0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.997 0.003
A04.8 Other specified bacterial intestinal infections
0.000 0.997 0.003
Z80.9 Family history of malignant neoplasm, unspecified
0.000 0.997 0.003
A04 Other bacterial intestinal infections
0.000 0.997 0.003
M35.3 Polymyalgia rheumatica
0.000 0.997 0.003
A87 Viral meningitis
0.000 0.997 0.003
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.997 0.003
E73 Lactose intolerance
0.000 0.997 0.003
S32.10 Fracture of sacrum (closed)
0.003 0.997 0.000
B02.2 Zoster with other nervous system involvement
0.000 0.997 0.003
C50.0 Nipple and areola
0.000 0.997 0.003
E79 Disorders of purine and pyrimidine metabolism
0.000 0.997 0.002
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.997 0.003
C50 Malignant neoplasm of breast
0.000 0.997 0.003
X41.0 Home
0.003 0.997 0.000
X41.8 Other specified place
0.003 0.997 0.000
X41.7 Farm
0.003 0.997 0.000
X41.6 Industrial and construction area
0.003 0.997 0.000
X41.5 Trade and service area
0.003 0.997 0.000
X41.4 Street and highway
0.003 0.997 0.000
X41.3 Sports and athletics area
0.003 0.997 0.000
X41.2 School, other institution and public administrative area
0.003 0.997 0.000
X41.1 Residential institution
0.003 0.997 0.000
C50.8 Overlapping lesion of breast
0.000 0.997 0.003
M34.0 Progressive systemic sclerosis
0.000 0.997 0.003
S32.40 Fracture of acetabulum (closed)
0.003 0.997 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.003 0.997 0.000
E77 Disorders of glycoprotein metabolism
0.001 0.997 0.002
E76 Disorders of glycosaminoglycan metabolism
0.001 0.997 0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.997 0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.997 0.002
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.000 0.997 0.002
E70 Disorders of aromatic amino-acid metabolism
0.000 0.997 0.002
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.000 0.997 0.003
S64.0 Injury of ulnar nerve at wrist and hand level
0.003 0.997 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.997 0.002
E84 Cystic fibrosis
0.001 0.997 0.002
K91.5 Postcholecystectomy syndrome
0.000 0.997 0.002
A00-A09 Intestinal infectious diseases
0.000 0.997 0.003
E72 Other disorders of amino-acid metabolism
0.001 0.997 0.002
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.003 0.997 0.000
E73.9 Lactose intolerance, unspecified
0.000 0.997 0.002
H25.9 Senile cataract, unspecified
0.000 0.997 0.003
F99 Mental disorder, not otherwise specified
0.003 0.997 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.002 0.997 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.000 0.998 0.002
E66.8 Other obesity
0.000 0.998 0.002
O43.8 Other placental disorders
0.000 0.998 0.002
S63.3 Traumatic rupture of ligament of wrist and carpus
0.002 0.998 0.000
A04.6 Enteritis due to Yersinia enterocolitica
0.000 0.998 0.002
A04.3 Enterohaemorrhagic Escherichia coli infection
0.000 0.998 0.002
A04.2 Enteroinvasive Escherichia coli infection
0.000 0.998 0.002
A04.1 Enterotoxigenic Escherichia coli infection
0.000 0.998 0.002
A04.0 Enteropathogenic Escherichia coli infection
0.000 0.998 0.002
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.998 0.002
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.998 0.002
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.998 0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.998 0.002
S32.1 Fracture of sacrum
0.002 0.998 0.000
E85 Amyloidosis
0.000 0.998 0.002
N02.9 Unspecified
0.000 0.998 0.002
A04.9 Bacterial intestinal infection, unspecified
0.000 0.998 0.002
A87.8 Other viral meningitis
0.000 0.998 0.002
A87.2 Lymphocytic choriomeningitis
0.000 0.998 0.002
A87.1 Adenoviral meningitis
0.000 0.998 0.002
A87.0 Enteroviral meningitis
0.000 0.998 0.002
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.998 0.002
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.998 0.002
N48.4 Impotence of organic origin
0.002 0.998 0.000
M22 Disorders of patella
0.000 0.998 0.002
A04.4 Other intestinal Escherichia coli infections
0.000 0.998 0.002
S32.4 Fracture of acetabulum
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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