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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1032485
log Bayes Factor = 6.4662
Chromosome 5   position 43,480,252  (GRCh37) Explore rs1032485 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
M47 Spondylosis
0.997 0.003 0.000
M47.8 Other spondylosis
0.995 0.005 0.000
M50-M54 Other dorsopathies
0.993 0.007 0.000
M15-M19 Arthrosis
0.992 0.008 0.000
M19 Other arthrosis
0.991 0.009 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.990 0.010 0.000
# Top node
0.990 0.010 0.000
M80-M85 Disorders of bone density and structure
0.987 0.013 0.000
M50 Cervical disk disorders
0.986 0.014 0.000
M50.2 Other cervical disk displacement
0.979 0.021 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.977 0.023 0.000
Chapter VI Diseases of the nervous system
0.977 0.023 0.000
Chapter X Diseases of the respiratory system
0.974 0.026 0.000
M19.9 Arthrosis, unspecified
0.971 0.029 0.000
M86-M90 Other osteopathies
0.970 0.030 0.000
M47.82 Other spondylosis (Cervical region)
0.969 0.031 0.000
M81 Osteoporosis without pathological fracture
0.968 0.032 0.000
M47.9 Spondylosis, unspecified
0.966 0.034 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.966 0.034 0.000
M19.0 Primary arthrosis of other joints
0.963 0.037 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.963 0.037 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.957 0.043 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.955 0.045 0.000
M81.9 Osteoporosis, unspecified
0.954 0.046 0.000
Chapter XX External causes of morbidity and mortality
0.951 0.049 0.000
M70-M79 Other soft tissue disorders
0.951 0.049 0.000
J09-J18 Influenza and pneumonia
0.944 0.056 0.000
G70-G73 Diseases of myoneural junction and muscle
0.940 0.060 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.934 0.066 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.933 0.067 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.933 0.067 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.927 0.073 0.000
M86 Osteomyelitis
0.925 0.075 0.000
M79.7 Fibromyalgia
0.923 0.077 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.923 0.077 0.000
J40-J47 Chronic lower respiratory diseases
0.918 0.082 0.000
M79.79 Fibromyalgia (Site unspecified)
0.917 0.083 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.911 0.089 0.000
G90-G99 Other disorders of the nervous system
0.910 0.090 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.908 0.092 0.000
J43 Emphysema
0.908 0.092 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.907 0.093 0.000
J95-J99 Other diseases of the respiratory system
0.905 0.095 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.905 0.095 0.000
T17 Foreign body in respiratory tract
0.904 0.096 0.000
M54 Dorsalgia
0.903 0.097 0.000
J43.9 Emphysema, unspecified
0.898 0.102 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.895 0.105 0.000
M40-M43 Deforming dorsopathies
0.895 0.105 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.894 0.106 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.888 0.112 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.886 0.114 0.000
M18 Arthrosis of first carpometacarpal joint
0.884 0.116 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.883 0.117 0.000
M47.86 Other spondylosis (Lumbar region)
0.877 0.123 0.000
G70 Myasthenia gravis and other myoneural disorders
0.870 0.130 0.000
S50-S59 Injuries to the elbow and forearm
0.869 0.131 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.868 0.132 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.867 0.133 0.000
J44 Other chronic obstructive pulmonary disease
0.864 0.136 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.863 0.137 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.862 0.138 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.862 0.138 0.000
G71 Primary disorders of muscles
0.861 0.139 0.000
M81.98 Osteoporosis, unspecified (Other)
0.861 0.139 0.000
M91-M94 Chondropathies
0.861 0.139 0.000
J60-J70 Lung diseases due to external agents
0.859 0.141 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.853 0.147 0.000
M86.9 Osteomyelitis, unspecified
0.853 0.147 0.000
J98 Other respiratory disorders
0.853 0.147 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.845 0.155 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.844 0.156 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.844 0.156 0.000
M43 Other deforming dorsopathies
0.843 0.157 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.835 0.165 0.000
Y40 Systemic antibiotics
0.831 0.169 0.000
Y60.0 During surgical operation
0.830 0.170 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.830 0.170 0.000
M87 Osteonecrosis
0.829 0.171 0.000
M79.2 Neuralgia and neuritis, unspecified
0.824 0.176 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.823 0.177 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.820 0.180 0.000
T17.2 Foreign body in pharynx
0.820 0.180 0.000
M50.1 Cervical disk disorder with radiculopathy
0.820 0.180 0.000
G70.0 Myasthenia gravis
0.819 0.180 0.000
M47.89 Other spondylosis (Site unspecified)
0.819 0.181 0.000
M86.6 Other chronic osteomyelitis
0.811 0.189 0.000
T00-T07 Injuries involving multiple body regions
0.810 0.190 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.809 0.191 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.808 0.192 0.000
T81 Complications of procedures, not elsewhere classified
0.807 0.193 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.806 0.194 0.000
G62 Other polyneuropathies
0.806 0.194 0.000
S90-S99 Injuries to the ankle and foot
0.804 0.196 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.802 0.198 0.000
Q23 Congenital malformations of aortic and mitral valves
0.801 0.199 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.798 0.202 0.000
S51 Open wound of forearm
0.797 0.203 0.000
S20-S29 Injuries to the thorax
0.795 0.205 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.794 0.206 0.000
M48 Other spondylopathies
0.793 0.206 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.792 0.208 0.000
X60-X84 Intentional self-harm
0.791 0.209 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.788 0.212 0.000
M54.4 Lumbago with sciatica
0.787 0.213 0.000
M54.9 Dorsalgia, unspecified
0.784 0.216 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.781 0.219 0.000
M85 Other disorders of bone density and structure
0.778 0.222 0.000
J14 Pneumonia due to Haemophilus influenzae
0.778 0.222 0.000
M84 Disorders of continuity of bone
0.777 0.222 0.000
M19.98 Arthrosis, unspecified (Other)
0.776 0.224 0.000
G91 Hydrocephalus
0.776 0.224 0.000
J98.1 Pulmonary collapse
0.776 0.224 0.000
M43.1 Spondylolisthesis
0.775 0.225 0.000
M19.1 Posttraumatic arthrosis of other joints
0.773 0.227 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.772 0.228 0.000
G71.1 Myotonic disorders
0.771 0.229 0.000
J86 Pyothorax
0.766 0.234 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.764 0.236 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.763 0.237 0.000
Q23.1 Congenital insufficiency of aortic valve
0.763 0.237 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.763 0.237 0.000
J10 Influenza due to identified influenza virus
0.762 0.238 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.761 0.239 0.000
V80-V89 Other land transport accidents
0.760 0.240 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.759 0.241 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.757 0.243 0.000
S10-S19 Injuries to the neck
0.755 0.245 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.754 0.246 0.000
J17 Pneumonia in diseases classified elsewhere
0.753 0.247 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.752 0.248 0.000
M19.2 Other secondary arthrosis
0.751 0.249 0.000
M77 Other enthesopathies
0.750 0.250 0.000
V10-V19 Pedal cyclist injured in transport accident
0.749 0.251 0.000
M49 Spondylopathies in diseases classified elsewhere
0.748 0.252 0.000
M80 Osteoporosis with pathological fracture
0.748 0.252 0.000
G62.9 Polyneuropathy, unspecified
0.747 0.253 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.745 0.255 0.000
M15 Polyarthrosis
0.744 0.256 0.000
M54.2 Cervicalgia
0.743 0.257 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.740 0.259 0.000
T17.5 Foreign body in bronchus
0.740 0.260 0.000
G93 Other disorders of brain
0.740 0.260 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.738 0.262 0.000
W20-W49 Exposure to inanimate mechanical forces
0.738 0.262 0.000
M76 Enthesopathies of lower limb, excluding foot
0.737 0.263 0.000
Chapter I Certain infectious and parasitic diseases
0.737 0.263 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.736 0.264 0.000
M00-M03 Infectious arthropathies
0.734 0.266 0.000
T51 Toxic effect of alcohol
0.734 0.266 0.000
M53 Other dorsopathies, not elsewhere classified
0.733 0.266 0.000
T62 Toxic effect of other noxious substances eaten as food
0.733 0.267 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.732 0.268 0.000
T82.3 Mechanical complication of other vascular grafts
0.731 0.269 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.730 0.270 0.000
E70-E90 Metabolic disorders
0.730 0.270 0.000
Y40.9 Systemic antibiotic, unspecified
0.729 0.271 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.728 0.272 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.728 0.272 0.000
G60 Hereditary and idiopathic neuropathy
0.727 0.272 0.000
T86 Failure and rejection of transplanted organs and tissues
0.726 0.274 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.725 0.275 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.725 0.275 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.724 0.276 0.000
J43.2 Centrilobular emphysema
0.722 0.278 0.000
V20-V29 Motorcycle rider injured in transport accident
0.720 0.280 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.720 0.280 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.719 0.281 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.719 0.281 0.000
Y48 Anaesthetics and therapeutic gases
0.718 0.282 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.718 0.282 0.000
T23 Burn and corrosion of wrist and hand
0.716 0.284 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
M89 Other disorders of bone
0.714 0.286 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.713 0.287 0.000
M47.84 Other spondylosis (Thoracic region)
0.713 0.287 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.713 0.287 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.713 0.287 0.000
M43.0 Spondylolysis
0.713 0.287 0.000
G97.8 Other postprocedural disorders of nervous system
0.712 0.288 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
G61 Inflammatory polyneuropathy
0.711 0.289 0.000
M87.9 Osteonecrosis, unspecified
0.711 0.289 0.000
M19.8 Other specified arthrosis
0.710 0.289 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.710 0.290 0.000
Q00-Q07 Congenital malformations of the nervous system
0.710 0.290 0.000
T33-T35 Frostbite
0.710 0.290 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.710 0.290 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.709 0.290 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.709 0.291 0.000
M79.5 Residual foreign body in soft tissue
0.708 0.292 0.000
J98.8 Other specified respiratory disorders
0.708 0.292 0.000
M83 Adult osteomalacia
0.708 0.292 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.707 0.293 0.000
M50.9 Cervical disk disorder, unspecified
0.707 0.293 0.000
M50.8 Other cervical disk disorders
0.707 0.293 0.000
M48.0 Spinal stenosis
0.704 0.296 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.703 0.296 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.703 0.297 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.703 0.297 0.000
M93 Other osteochondropathies
0.702 0.298 0.000
X20-X29 Contact with venomous animals and plants
0.702 0.298 0.000
M82 Osteoporosis in diseases classified elsewhere
0.702 0.298 0.000
M79.8 Other specified soft tissue disorders
0.701 0.299 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.700 0.300 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.699 0.301 0.000
M88 Paget's disease of bone [osteitis deformans]
0.698 0.302 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.698 0.302 0.000
M71 Other bursopathies
0.698 0.302 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.698 0.302 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.698 0.302 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.697 0.303 0.000
Y44 Agents primarily affecting blood constituents
0.696 0.304 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.696 0.304 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.695 0.305 0.000
M81.8 Other osteoporosis
0.694 0.306 0.000
M81.6 Localised osteoporosis [Lequesne]
0.694 0.306 0.000
M81.5 Idiopathic osteoporosis
0.694 0.306 0.000
M81.1 Postoophorectomy osteoporosis
0.694 0.306 0.000
M81.0 Postmenopausal osteoporosis
0.694 0.306 0.000
T43.2 Other and unspecified antidepressants
0.694 0.306 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.693 0.307 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.693 0.307 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.693 0.307 0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)
0.693 0.307 0.000
S54 Injury of nerves at forearm level
0.692 0.308 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.691 0.309 0.000
M54.8 Other dorsalgia
0.691 0.309 0.000
M19.08 Primary arthrosis of other joints (Other)
0.691 0.309 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.691 0.309 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.691 0.309 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.690 0.310 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.690 0.310 0.000
V40-V49 Car occupant injured in transport accident
0.689 0.311 0.000
M90 Osteopathies in diseases classified elsewhere
0.689 0.311 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.688 0.312 0.000
M81.2 Osteoporosis of disuse
0.688 0.312 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.688 0.312 0.000
M54.1 Radiculopathy
0.687 0.313 0.000
T79-T79 Certain early complications of trauma
0.687 0.313 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.687 0.313 0.000
M50.3 Other cervical disk degeneration
0.687 0.313 0.000
E86 Volume depletion
0.686 0.314 0.000
S20 Superficial injury of thorax
0.686 0.314 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.684 0.316 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.684 0.316 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.684 0.316 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.684 0.316 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.684 0.316 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.683 0.317 0.000
T92 Sequelae of injuries of upper limb
0.683 0.317 0.000
G03 Meningitis due to other and unspecified causes
0.683 0.317 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.682 0.318 0.000
Y35-Y36 Legal intervention and operations of war
0.682 0.318 0.000
Y10-Y34 Event of undetermined intent
0.682 0.318 0.000
X85-X99 Assault
0.682 0.318 0.000
X30-X39 Exposure to forces of nature
0.682 0.318 0.000
X10-X19 Contact with heat and hot substances
0.682 0.318 0.000
X00-X09 Exposure to smoke, fire and flames
0.682 0.318 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.682 0.318 0.000
W75-W84 Other accidental threats to breathing
0.682 0.318 0.000
W65-W74 Accidental drowning and submersion
0.682 0.318 0.000
V98-V99 Other and unspecified transport accidents
0.682 0.318 0.000
V95-V97 Air and space transport accidents
0.682 0.318 0.000
V90-V94 Water transport accidents
0.682 0.318 0.000
V70-V79 Bus occupant injured in transport accident
0.682 0.318 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.682 0.318 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.682 0.318 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.682 0.318 0.000
V01-V09 Pedestrian injured in transport accident
0.682 0.318 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.682 0.318 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.682 0.318 0.000
S32 Fracture of lumbar spine and pelvis
0.681 0.319 0.000
S51.8 Open wound of other parts of forearm
0.681 0.319 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.681 0.319 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.679 0.321 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.679 0.321 0.000
M48.09 Spinal stenosis (Site unspecified)
0.678 0.322 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.678 0.322 0.000
J86.0 Pyothorax with fistula
0.677 0.323 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.677 0.323 0.000
J12 Viral pneumonia, not elsewhere classified
0.677 0.323 0.000
J09 Influenza due to certain identified influenza virus
0.677 0.323 0.000
B95-B98 Bacterial, viral and other infectious agents
0.677 0.323 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.677 0.323 0.000
Y57 Other and unspecified drugs and medicaments
0.676 0.324 0.000
Y54.3 Benzothiadiazine derivatives
0.676 0.324 0.000
J40 Bronchitis, not specified as acute or chronic
0.676 0.324 0.000
T39.1 4-Aminophenol derivatives
0.675 0.325 0.000
M84.0 Malunion of fracture
0.674 0.326 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.674 0.326 0.000
B25-B34 Other viral diseases
0.674 0.326 0.000
G96 Other disorders of central nervous system
0.671 0.329 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
M94 Other disorders of cartilage
0.670 0.330 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.670 0.330 0.000
Y41.5 Antiviral drugs
0.669 0.330 0.000
Y00-Y09 Assault
0.669 0.331 0.000
T19 Foreign body in genito-urinary tract
0.669 0.331 0.000
T15 Foreign body on external eye
0.669 0.331 0.000
T16 Foreign body in ear
0.669 0.331 0.000
M79.3 Panniculitis, unspecified
0.669 0.331 0.000
S92 Fracture of foot, except ankle
0.669 0.331 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.669 0.331 0.000
T01 Open wounds involving multiple body regions
0.668 0.332 0.000
W50-W64 Exposure to animate mechanical forces
0.668 0.332 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.667 0.333 0.000
J60 Coalworker's pneumoconiosis
0.667 0.333 0.000
M60-M63 Disorders of muscles
0.667 0.333 0.000
Q27 Other congenital malformations of peripheral vascular system
0.667 0.333 0.000
Y65 Other misadventures during surgical and medical care
0.667 0.333 0.000
J10.0 Influenza with pneumonia, influenza virus identified
0.666 0.334 0.000
Y54.8 Agents affecting uric acid metabolism
0.666 0.334 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.666 0.334 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.665 0.335 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.664 0.336 0.000
M86.66 Other chronic osteomyelitis (Lower leg)
0.664 0.336 0.000
M86.8 Other osteomyelitis
0.663 0.336 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.663 0.336 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.663 0.336 0.000
M86.3 Chronic multifocal osteomyelitis
0.663 0.336 0.000
M86.2 Subacute osteomyelitis
0.663 0.336 0.000
M86.1 Other acute osteomyelitis
0.663 0.336 0.000
M86.0 Acute haematogenous osteomyelitis
0.663 0.336 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.663 0.336 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.663 0.337 0.000
S27 Injury of other and unspecified intrathoracic organs
0.663 0.337 0.000
M85.6 Other cyst of bone
0.663 0.337 0.000
G93.0 Cerebral cysts
0.663 0.337 0.000
S31 Open wound of abdomen, lower back and pelvis
0.663 0.337 0.000
M79.70 Fibromyalgia (Multiple sites)
0.663 0.337 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.663 0.337 0.000
Q50-Q56 Congenital malformations of genital organs
0.662 0.338 0.000
M79.78 Fibromyalgia (Other)
0.662 0.338 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.662 0.338 0.000
M79.76 Fibromyalgia (Lower leg)
0.662 0.338 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.662 0.338 0.000
M79.74 Fibromyalgia (Hand)
0.662 0.338 0.000
M79.73 Fibromyalgia (Forearm)
0.662 0.338 0.000
M79.72 Fibromyalgia (Upper arm)
0.662 0.338 0.000
M79.71 Fibromyalgia (Shoulder region)
0.662 0.338 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.662 0.338 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.661 0.339 0.000
M40 Kyphosis and lordosis
0.661 0.339 0.000
D55-D59 Haemolytic anaemias
0.659 0.341 0.000
J41 Simple and mucopurulent chronic bronchitis
0.658 0.342 0.000
G91.9 Hydrocephalus, unspecified
0.657 0.343 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.656 0.344 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.655 0.345 0.000
M79.1 Myalgia
0.655 0.345 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.654 0.346 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.653 0.347 0.000
G92 Toxic encephalopathy
0.652 0.348 0.000
G71.0 Muscular dystrophy
0.652 0.348 0.000
Y40.8 Other systemic antibiotics
0.652 0.348 0.000
T21 Burn and corrosion of trunk
0.652 0.348 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.651 0.349 0.000
Y59 Other and unspecified vaccines and biological substances
0.651 0.349 0.000
Y58 Bacterial vaccines
0.651 0.349 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.651 0.349 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.651 0.349 0.000
J43.8 Other emphysema
0.651 0.349 0.000
J43.1 Panlobular emphysema
0.651 0.349 0.000
J43.0 MacLeod's syndrome
0.651 0.349 0.000
Y64 Contaminated medical or biological substances
0.650 0.349 0.000
Y63 Failure in dosage during surgical and medical care
0.650 0.349 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.650 0.349 0.000
Y69 Unspecified misadventure during surgical and medical care
0.650 0.349 0.000
Y66 Nonadministration of surgical and medical care
0.650 0.349 0.000
J96 Respiratory failure, not elsewhere classified
0.649 0.351 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.649 0.351 0.000
S51.9 Open wound of forearm, part unspecified
0.649 0.351 0.000
G64 Other disorders of peripheral nervous system
0.648 0.351 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.648 0.352 0.000
T17.8 Foreign body in other and multiple parts of respiratory tract
0.648 0.352 0.000
T17.4 Foreign body in trachea
0.648 0.352 0.000
T17.3 Foreign body in larynx
0.648 0.352 0.000
T17.1 Foreign body in nostril
0.648 0.352 0.000
T17.0 Foreign body in nasal sinus
0.648 0.352 0.000
M54.0 Panniculitis affecting regions of neck and back
0.647 0.352 0.000
M43.12 Spondylolisthesis (Cervical region)
0.647 0.353 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.646 0.354 0.000
Y54.5 Other diuretics
0.646 0.354 0.000
S52 Fracture of forearm
0.645 0.355 0.000
T58 Toxic effect of carbon monoxide
0.644 0.355 0.000
G90 Disorders of autonomic nervous system
0.644 0.356 0.000
G91.8 Other hydrocephalus
0.644 0.356 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.643 0.356 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.642 0.358 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.642 0.358 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.642 0.358 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.642 0.358 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.642 0.358 0.000
M42 Spinal osteochondrosis
0.642 0.358 0.000
M19.94 Arthrosis, unspecified (Hand)
0.642 0.358 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.641 0.359 0.000
Q35-Q37 Cleft lip and cleft palate
0.641 0.359 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.641 0.359 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.641 0.359 0.000
M92 Other juvenile osteochondrosis
0.640 0.360 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.640 0.360 0.000
M43.02 Spondylolysis (Cervical region)
0.639 0.361 0.000
M84.4 Pathological fracture, not elsewhere classified
0.639 0.361 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.638 0.361 0.000
M79.9 Soft tissue disorder, unspecified
0.638 0.362 0.000
G93.4 Encephalopathy, unspecified
0.638 0.362 0.000
M77.4 Metatarsalgia
0.637 0.363 0.000
T87 Complications peculiar to reattachment and amputation
0.637 0.363 0.000
J98.6 Disorders of diaphragm
0.637 0.363 0.000
T62.9 Noxious substance eaten as food, unspecified
0.637 0.363 0.000
M81.4 Drug-induced osteoporosis
0.636 0.364 0.000
J11 Influenza, virus not identified
0.636 0.364 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.635 0.365 0.000
S36 Injury of intra-abdominal organs
0.635 0.365 0.000
S70-S79 Injuries to the hip and thigh
0.634 0.366 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.634 0.366 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.634 0.366 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.634 0.366 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.634 0.366 0.000
J15.4 Pneumonia due to other streptococci
0.633 0.366 0.000
G10 Huntington's disease
0.633 0.367 0.000
G62.8 Other specified polyneuropathies
0.633 0.367 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.632 0.368 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.631 0.369 0.000
M54.6 Pain in thoracic spine
0.631 0.369 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.631 0.369 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.629 0.371 0.000
M79.0 Rheumatism, unspecified
0.629 0.371 0.000
M87.8 Other osteonecrosis
0.629 0.371 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.628 0.371 0.000
M54.29 Cervicalgia-Site unspe
0.628 0.372 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.628 0.372 0.000
M50.0 Cervical disk disorder with myelopathy
0.628 0.372 0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)
0.627 0.373 0.000
M72 Fibroblastic disorders
0.626 0.374 0.000
S21 Open wound of thorax
0.625 0.374 0.000
E88 Other metabolic disorders
0.625 0.375 0.000
L20-L30 Dermatitis and eczema
0.625 0.375 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.624 0.376 0.000
G70.9 Myoneural disorder, unspecified
0.624 0.376 0.000
G70.8 Other specified myoneural disorders
0.624 0.376 0.000
G70.2 Congenital and developmental myasthenia
0.624 0.376 0.000
G70.1 Toxic myoneural disorders
0.624 0.376 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.624 0.376 0.000
S59 Other and unspecified injuries of forearm
0.623 0.377 0.000
S58 Traumatic amputation of forearm
0.623 0.377 0.000
S57 Crushing injury of forearm
0.623 0.377 0.000
S55 Injury of blood vessels at forearm level
0.623 0.377 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.623 0.377 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.623 0.377 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.623 0.377 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.622 0.378 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.622 0.378 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.622 0.378 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.622 0.378 0.000
T65 Toxic effect of other and unspecified substances
0.621 0.379 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.621 0.379 0.000
T60 Toxic effect of pesticides
0.621 0.379 0.000
T57 Toxic effect of other inorganic substances
0.621 0.379 0.000
T56 Toxic effect of metals
0.621 0.379 0.000
T54 Toxic effect of corrosive substances
0.621 0.379 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.621 0.379 0.000
T52 Toxic effect of organic solvents
0.621 0.379 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.621 0.379 0.000
T55 Toxic effect of soaps and detergents
0.621 0.379 0.000
J17.3 Pneumonia in parasitic diseases
0.621 0.379 0.000
D59 Acquired haemolytic anaemia
0.620 0.380 0.000
T59 Toxic effect of other gases, fumes and vapours
0.620 0.380 0.000
S20.2 Contusion of thorax
0.620 0.380 0.000
Q25 Congenital malformations of great arteries
0.619 0.380 0.000
G61.8 Other inflammatory polyneuropathies
0.619 0.381 0.000
S51.0 Open wound of elbow
0.619 0.381 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.619 0.381 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.619 0.381 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.619 0.381 0.000
Y60.9 During unspecified surgical and medical care
0.618 0.382 0.000
Y60.8 During other surgical and medical care
0.618 0.382 0.000
Y60.7 During administration of enema
0.618 0.382 0.000
Y60.6 During aspiration, puncture and other catheterisation
0.618 0.382 0.000
Y60.5 During heart catheterisation
0.618 0.382 0.000
Y60.3 During injection or immunisation
0.618 0.382 0.000
Y60.2 During kidney dialysis or other perfusion
0.618 0.382 0.000
Y60.1 During infusion or transfusion
0.618 0.382 0.000
G30-G32 Other degenerative diseases of the nervous system
0.618 0.382 0.000
G71.9 Primary disorder of muscle, unspecified
0.617 0.382 0.000
G71.8 Other primary disorders of muscles
0.617 0.382 0.000
G71.2 Congenital myopathies
0.617 0.382 0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)
0.616 0.384 0.000
J70 Respiratory conditions due to other external agents
0.616 0.384 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.616 0.384 0.000
J66 Airway disease due to specific organic dust
0.616 0.384 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.616 0.384 0.000
J62 Pneumoconiosis due to dust containing silica
0.616 0.384 0.000
J65 Pneumoconiosis associated with tuberculosis
0.616 0.384 0.000
J64 Unspecified pneumoconiosis
0.616 0.384 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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