TreeWAS – Variant ID: rs1040503

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D68.2 Hereditary deficiency of other clotting factors	1.000	0.000	0.000
D68.5 Primary Thrombophilia	0.978	0.022	0.000
D68 Other coagulation defects	0.977	0.023	0.000
D68.8 Other specified coagulation defects	0.745	0.255	0.000
D68.1 Hereditary factor XI deficiency	0.724	0.276	0.000
D68.6 Other Thrombophilia	0.705	0.295	0.000
D68.4 Acquired coagulation factor deficiency	0.650	0.349	0.000
Z86.7 Personal history of diseases of the circulatory system	0.611	0.389	0.000
D68.9 Coagulation defect, unspecified	0.473	0.527	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.406	0.594	0.001
D68.0 Von Willebrand's disease	0.405	0.594	0.000
N60.1 Diffuse cystic mastopathy	0.382	0.618	0.000
N60 Benign mammary dysplasia	0.367	0.633	0.000
N60.4 Mammary duct ectasia	0.357	0.643	0.000
N60.0 Solitary cyst of breast	0.331	0.669	0.000
N60.9 Benign mammary dysplasia, unspecified	0.315	0.685	0.000
N60.2 Fibroadenosis of breast	0.258	0.742	0.000
N60.3 Fibrosclerosis of breast	0.242	0.758	0.000
N60.8 Other benign mammary dysplasias	0.227	0.773	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.831	0.169
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.126	0.874	0.000
D67 Hereditary factor IX deficiency	0.090	0.910	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.081	0.919	0.000
M23.3 Other meniscus derangements	0.000	0.929	0.071
D66 Hereditary factor VIII deficiency	0.070	0.930	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.938	0.062
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.939	0.061
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.941	0.059
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.948	0.052
M23.37 Other meniscus derangements-Capsular lig	0.000	0.949	0.051
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.957	0.043
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.964	0.036
D69 Purpura and other haemorrhagic conditions	0.036	0.964	0.000
D69.5 Secondary thrombocytopenia	0.031	0.969	0.000
D69.8 Other specified haemorrhagic conditions	0.028	0.972	0.000
D69.0 Allergic purpura	0.028	0.972	0.000
D69.2 Other nonthrombocytopenic purpura	0.027	0.973	0.000
D69.1 Qualitative platelet defects	0.026	0.974	0.000
D69.4 Other primary thrombocytopenia	0.021	0.979	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.019	0.981	0.000
Z93.2 Ileostomy status	0.000	0.982	0.018
Z93 Artificial opening status	0.000	0.983	0.017
Z93.3 Colostomy status	0.000	0.984	0.016
Z93.4 Other artificial openings of gastro-intestinal tract status	0.000	0.985	0.015
Z93.9 Artificial opening status, unspecified	0.000	0.985	0.015
Z93.1 Gastrostomy status	0.000	0.985	0.015
Z93.8 Other artificial opening status	0.000	0.986	0.014
Z93.0 Tracheostomy status	0.000	0.986	0.014
Z89.6 Acquired absence of leg above knee	0.014	0.986	0.000
Z89 Acquired absence of limb	0.014	0.986	0.000
D69.9 Haemorrhagic condition, unspecified	0.013	0.986	0.001
M79.86 Other specified soft tissue disorders (Lower leg)	0.013	0.987	0.000
Z89.5 Acquired absence of leg at or below knee	0.013	0.987	0.000
Z89.9 Acquired absence of limb, unspecified	0.013	0.987	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.013	0.987	0.000
M79.18 Myalgia (Other)	0.013	0.987	0.000
H74.4 Polyp of middle ear	0.000	0.989	0.011
Z93.6 Other artificial openings of urinary tract status	0.000	0.989	0.011
D69.6 Thrombocytopenia, unspecified	0.011	0.989	0.000
Z89.2 Acquired absence of upper limb above wrist	0.010	0.990	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.010	0.990	0.000
Z89.1 Acquired absence of hand and wrist	0.010	0.990	0.000
A41.9 Septicaemia, unspecified	0.010	0.990	0.000
Z89.4 Acquired absence of foot and ankle	0.010	0.990	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.990	0.010
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.010	0.990	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.009	0.990	0.000
M48.02 Spinal stenosis (Cervical region)	0.009	0.991	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.991	0.009
C71.9 Brain, unspecified	0.000	0.992	0.008
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.008	0.992	0.000
C71 Malignant neoplasm of brain	0.000	0.992	0.008
Q61.2 Polycystic kidney, adult type	0.000	0.992	0.008
Z90.1 Acquired absence of breast(s)	0.007	0.993	0.000
Z93.5 Cystostomy status	0.000	0.993	0.007
C71.1 Frontal lobe	0.000	0.993	0.007
Q61 Cystic kidney disease	0.000	0.993	0.007
C71.8 Overlapping lesion of brain	0.000	0.993	0.007
C71.0 Cerebrum, except lobes and ventricles	0.000	0.993	0.007
N60-N64 Disorders of breast	0.006	0.994	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.994	0.006
C71.4 Occipital lobe	0.000	0.994	0.006
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.006	0.994	0.000
C71.2 Temporal lobe	0.000	0.994	0.006
C71.6 Cerebellum	0.000	0.994	0.006
C71.5 Cerebral ventricle	0.000	0.994	0.006
D69.3 Idiopathic thrombocytopenic purpura	0.005	0.994	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.994	0.006
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.006	0.994	0.000
C71.3 Parietal lobe	0.000	0.995	0.005
C71.7 Brain stem	0.000	0.995	0.005
H74 Other disorders of middle ear and mastoid	0.000	0.995	0.005
Q61.5 Medullary cystic kidney	0.000	0.995	0.005
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.995	0.005
Q61.8 Other cystic kidney diseases	0.000	0.995	0.005
Q61.1 Polycystic kidney, infantile type	0.000	0.995	0.005
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.995	0.005
M79.1 Myalgia	0.005	0.995	0.000
Q61.4 Renal dysplasia	0.000	0.995	0.005
Q61.9 Cystic kidney disease, unspecified	0.000	0.995	0.005
M47.99 Spondylosis, unspecified (Site unspecified)	0.005	0.995	0.000
Q61.0 Congenital single renal cyst	0.000	0.995	0.005
T31.0 Burns involving less than 10% of body surface	0.005	0.995	0.000
M54.9 Dorsalgia, unspecified	0.005	0.995	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.004	0.996	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.004	0.996	0.000
Z86 Personal history of certain other diseases	0.004	0.996	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.004	0.996	0.000
Z86.6 Personal history of diseases of the nervous system and sense organs	0.004	0.996	0.000
M23 Internal derangement of knee	0.000	0.996	0.004
M23.5 Chronic instability of knee	0.000	0.996	0.004
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.996	0.004
N62 Hypertrophy of breast	0.004	0.996	0.000
M79.11 Myalgia (Shoulder region)	0.004	0.996	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.996	0.004
Z87.8 Personal history of other specified conditions	0.004	0.996	0.000
H74.1 Adhesive middle ear disease	0.000	0.996	0.004
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.004	0.996	0.000
I80 Phlebitis and thrombophlebitis	0.004	0.996	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.004	0.996	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.004
M23.9 Internal derangement of knee, unspecified	0.000	0.996	0.004
M25.88 Other specified joint disorders (Other)	0.004	0.996	0.000
M25.83 Other specified joint disorders (Forearm)	0.004	0.996	0.000
M25.8 Other specified joint disorders	0.004	0.996	0.000
M79.17 Myalgia (Ankle and foot)	0.004	0.996	0.000
M79.14 Myalgia (Hand)	0.004	0.996	0.000
M79.13 Myalgia (Forearm)	0.004	0.996	0.000
M79.12 Myalgia (Upper arm)	0.004	0.996	0.000
M79.16 Myalgia (Lower leg)	0.004	0.996	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.996	0.004
H74.0 Tympanosclerosis	0.000	0.996	0.004
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.996	0.004
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.004	0.996	0.000
C70 Malignant neoplasm of meninges	0.000	0.996	0.004
M25.87 Other specified joint disorders (Ankle and foot)	0.004	0.996	0.000
K83.0 Cholangitis	0.004	0.996	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.996	0.004
M54.92 Dorsalgia, unspecified (Cervical region)	0.004	0.996	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.004	0.996	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.003	0.996	0.000
D55-D59 Haemolytic anaemias	0.003	0.996	0.000
M25.82 Other specified joint disorders (Upper arm)	0.003	0.996	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.003	0.996	0.000
K83.1 Obstruction of bile duct	0.004	0.996	0.000
D56 Thalassaemia	0.003	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.003	0.996	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.003	0.997	0.000
K27 Peptic ulcer, site unspecified	0.003	0.997	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.997	0.003
C70.0 Cerebral meninges	0.000	0.997	0.003
D56.3 Thalassaemia trait	0.003	0.997	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.003	0.997	0.000
M23.1 Discoid meniscus (congenital)	0.000	0.997	0.003
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.997	0.003
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.997	0.003
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.003
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.997	0.003
C15.9 Oesophagus, unspecified	0.000	0.997	0.003
K35.3 Acute appendicitis with localized peritonitis	0.000	0.997	0.003
G44.0 Cluster headache syndrome	0.003	0.997	0.000
M13.98 Arthritis, unspecified (Other)	0.003	0.997	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.997	0.003
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.997	0.003
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.997	0.003
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.997	0.003
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.997	0.003
M79.19 Myalgia (Site unspecified)	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.003	0.997	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.003	0.997	0.000
M25.86 Other specified joint disorders (Lower leg)	0.003	0.997	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.003	0.997	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.997	0.003
D56.1 Beta thalassaemia	0.003	0.997	0.000
C72.0 Spinal cord	0.000	0.997	0.003
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.003	0.997	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.003
C70.9 Meninges, unspecified	0.000	0.997	0.003
C70.1 Spinal meninges	0.000	0.997	0.003
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.997	0.003
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.003	0.997	0.000
K27.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.003	0.997	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.003	0.997	0.000
D57 Sickle-cell disorders	0.003	0.997	0.000
D55 Anaemia due to enzyme disorders	0.003	0.997	0.000
D56.9 Thalassaemia, unspecified	0.003	0.997	0.000
D56.8 Other thalassaemias	0.003	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.003	0.997	0.000
D56.2 Delta-beta thalassaemia	0.003	0.997	0.000
D56.0 Alpha thalassaemia	0.003	0.997	0.000
K27.4 Chronic or unspecified with haemorrhage	0.003	0.997	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
C69 Malignant neoplasm of eye and adnexa	0.000	0.997	0.003
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.997	0.003
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.003	0.997	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.003	0.997	0.000
C72.9 Central nervous system, unspecified	0.000	0.997	0.003
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.997	0.003
C72.5 Other and unspecified cranial nerves	0.000	0.997	0.003
C72.4 Acoustic nerve	0.000	0.997	0.003
C72.3 Optic nerve	0.000	0.997	0.003
C72.2 Olfactory nerve	0.000	0.997	0.003
C72.1 Cauda equina	0.000	0.997	0.003
E89.3 Postprocedural hypopituitarism	0.003	0.997	0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.003	0.997	0.000
K27.5 Chronic or unspecified with perforation	0.003	0.997	0.000
K27.2 Acute with both haemorrhage and perforation	0.003	0.997	0.000
K27.1 Acute with perforation	0.003	0.997	0.000
K27.0 Acute with haemorrhage	0.003	0.997	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.997	0.003
M25.81 Other specified joint disorders (Shoulder region)	0.003	0.997	0.000
N90.4 Leukoplakia of vulva	0.003	0.997	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.002
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.997	0.002
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.997	0.002
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.002
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.002
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.002
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.002
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.997	0.002
M79.10 Myalgia (Multiple sites)	0.003	0.997	0.000
D59 Acquired haemolytic anaemia	0.003	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.997	0.003
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.003	0.997	0.000
K27.3 Acute without haemorrhage or perforation	0.002	0.997	0.000
M23.0 Cystic meniscus	0.000	0.997	0.002
J03.9 Acute tonsillitis, unspecified	0.003	0.997	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
R58 Haemorrhage, not elsewhere classified	0.000	0.997	0.003
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.002
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.997	0.002
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.997	0.002
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.997	0.002
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.002
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.002
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.002
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.997	0.002
C15.4 Middle third of oesophagus	0.000	0.997	0.002
C18.9 Colon, unspecified	0.000	0.998	0.002
K83 Other diseases of biliary tract	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.998	0.002
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.998	0.002
C69.0 Conjunctiva	0.000	0.998	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.002	0.998	0.000
M95.0 Acquired deformity of nose	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
C21.0 Anus, unspecified	0.000	0.998	0.002
C69.8 Overlapping lesion of eye and adnexa	0.000	0.998	0.002
C69.6 Orbit	0.000	0.998	0.002
C69.5 Lachrymal gland and duct	0.000	0.998	0.002
C69.4 Ciliary body	0.000	0.998	0.002
C69.1 Cornea	0.000	0.998	0.002
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
M47.2 Other spondylosis with radiculopathy	0.002	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
K81.1 Chronic cholecystitis	0.002	0.998	0.000
C69.3 Choroid	0.000	0.998	0.002
D59.8 Other acquired haemolytic anaemias	0.002	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
R94.4 Abnormal results of kidney function studies	0.002	0.998	0.000
T31 Burns classified according to extent of body surface involved	0.002	0.998	0.000
M23.07 Cystic meniscus-Capsular lig	0.000	0.998	0.002
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.998	0.002
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
M23.00 Cystic meniscus (Multiple sites)	0.000	0.998	0.002
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.998	0.000
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
M79.8 Other specified soft tissue disorders	0.002	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.998	0.002
C69.2 Retina	0.000	0.998	0.002
C07 Malignant neoplasm of parotid gland	0.000	0.998	0.002
C15.0 Cervical part of oesophagus	0.000	0.998	0.002
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.002
Y09.4 Street and highway	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
K83.5 Biliary cyst	0.002	0.998	0.000
K83.2 Perforation of bile duct	0.002	0.998	0.000
M54.3 Sciatica	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.000	0.998	0.002
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
C15.8 Overlapping lesion of oesophagus	0.000	0.998	0.002
C15.2 Abdominal part of oesophagus	0.000	0.998	0.002
C15.1 Thoracic part of oesophagus	0.000	0.998	0.002
C69.9 Eye, unspecified	0.000	0.998	0.002
K83.9 Disease of biliary tract, unspecified	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.998	0.002
Y04.5 Trade and service area	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.000	0.998	0.002
M43.1 Spondylolisthesis	0.000	0.998	0.002
M89.8 Other specified disorders of bone	0.002	0.998	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.000	0.998	0.002
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.002	0.998	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.002	0.998	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
C34.0 Main bronchus	0.000	0.998	0.002
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
Y04.8 Other specified place	0.002	0.998	0.000
M62.68 Muscle strain (Other)	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
K83.4 Spasm of sphincter of Oddi	0.002	0.998	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.002	0.998	0.000
C15.3 Upper third of oesophagus	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
Y04 Assault by bodily force	0.002	0.998	0.000
C21.1 Anal canal	0.000	0.998	0.002
G37.5 Concentric sclerosis [Balo]	0.002	0.998	0.000
G37.4 Subacute necrotising myelitis	0.002	0.998	0.000
G37.2 Central pontine myelinolysis	0.002	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.002	0.998	0.000
G37.0 Diffuse sclerosis	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
T31.9 Burns involving 90% or more of body surface	0.002	0.998	0.000
T31.8 Burns involving 80-89% of body surface	0.002	0.998	0.000
T31.7 Burns involving 70-79% of body surface	0.002	0.998	0.000
T31.6 Burns involving 60-69% of body surface	0.002	0.998	0.000
T31.5 Burns involving 50-59% of body surface	0.002	0.998	0.000
T31.4 Burns involving 40-49% of body surface	0.002	0.998	0.000
T31.3 Burns involving 30-39% of body surface	0.002	0.998	0.000
T31.2 Burns involving 20-29% of body surface	0.002	0.998	0.000
Y09 Assault by unspecified means	0.002	0.998	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
M47.8 Other spondylosis	0.002	0.998	0.000
M62.6 Muscle strain	0.002	0.998	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.000	0.998	0.002
K59.3 Megacolon, not elsewhere classified	0.000	0.998	0.002
M89.5 Osteolysis	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
C21 Malignant neoplasm of anus and anal canal	0.000	0.998	0.002
D84 Other immunodeficiencies	0.002	0.998	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.001	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
M23.4 Loose body in knee	0.001	0.998	0.001
M10.96 Gout, unspecified (Lower leg)	0.000	0.998	0.002
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.998	0.001
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.002	0.998	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.002	0.998	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.998	0.002
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
M54.35 Sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.34 Sciatica-Thoracic	0.002	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.002	0.998	0.000
M54.32 Sciatica-Cervical	0.002	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.002	0.998	0.000
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
Y09.8 Other specified place	0.002	0.998	0.000
M23.40 Loose body in knee-Mult sites	0.001	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.002	0.998	0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.998	0.002
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.998	0.002
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.998	0.002
D46.1 Refractory anaemia with sideroblasts	0.000	0.998	0.002
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
K83.3 Fistula of bile duct	0.001	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
M62.66 Muscle strain (Lower leg)	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.998	0.002
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
M89 Other disorders of bone	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.002	0.998	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.998	0.002
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.998	0.002
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.998	0.002
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.998	0.002
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.998	0.002
M47.86 Other spondylosis (Lumbar region)	0.002	0.998	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.998	0.000
D81.8 Other combined immunodeficiencies	0.001	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.998	0.000
D81.4 Nezelof's syndrome	0.001	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.998	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.001	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.001	0.998	0.000
M95.2 Other acquired deformity of head	0.002	0.998	0.000
O87.2 Haemorrhoids in the puerperium	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.000	0.998	0.002
M47 Spondylosis	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.998	0.002
M23.42 Loose body in knee-Pst lig/hrn men	0.001	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
K86.2 Cyst of pancreas	0.002	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
Y04.9 Unspecified place	0.001	0.998	0.000
Y04.4 Street and highway	0.001	0.998	0.000
Y04.0 Home	0.001	0.998	0.000
Y04.7 Farm	0.001	0.998	0.000
Y04.6 Industrial and construction area	0.001	0.998	0.000
Y04.3 Sports and athletics area	0.001	0.998	0.000
Y04.2 School, other institution and public administrative area	0.001	0.998	0.000
Y04.1 Residential institution	0.001	0.998	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.002	0.998	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
M23.43 Loose body in knee-Med lig/oth men	0.001	0.998	0.000
M43.12 Spondylolisthesis (Cervical region)	0.000	0.998	0.001
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.001	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
M54 Dorsalgia	0.002	0.998	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations