TreeWAS – Variant ID: rs1042116

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
C44 Other malignant neoplasms of skin	1.000	0.000	0.000
C44.2 Skin of ear and external auricular canal	0.998	0.002	0.000
C44.3 Skin of other and unspecified parts of face	0.985	0.015	0.000
C44.0 Skin of lip	0.984	0.016	0.000
C44.5 Skin of trunk	0.954	0.046	0.000
C44.6 Skin of upper limb, including shoulder	0.931	0.069	0.000
I21.9 Acute myocardial infarction, unspecified	0.893	0.107	0.000
C44.7 Skin of lower limb, including hip	0.886	0.114	0.000
C44.4 Skin of scalp and neck	0.883	0.117	0.000
C44.1 Skin of eyelid, including canthus	0.759	0.241	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.735	0.265	0.000
C44.8 Overlapping lesion of skin	0.717	0.283	0.000
K90 Intestinal malabsorption	0.000	0.309	0.691
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.399	0.601
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.580	0.420	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.459	0.541
E10.9 Without complications	0.000	0.473	0.527
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.527	0.473	0.000
K90.8 Other intestinal malabsorption	0.000	0.505	0.495
K90.3 Pancreatic steatorrhoea	0.000	0.505	0.495
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.505	0.495
K90.1 Tropical sprue	0.000	0.505	0.495
I21 Acute myocardial infarction	0.493	0.507	0.000
C82.0 Small cleaved cell, follicular	0.474	0.526	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.456	0.544	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.559	0.441
C82.3 Follicular lymphoma grade IIIa	0.435	0.565	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.433	0.567	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.420	0.580	0.000
E10.1 With ketoacidosis	0.000	0.592	0.408
C82.2 Large cell, follicular	0.396	0.604	0.000
E10.3 With ophthalmic complications	0.000	0.607	0.392
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.383	0.617	0.000
C82.6 Cutaneous follicle centre lymphoma	0.378	0.622	0.000
C82.5 Diffuse follicle centre lymphoma	0.378	0.622	0.000
C82.4 Follicular lymphoma grade IIIb	0.378	0.622	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.361	0.639	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.354	0.646	0.000
E10.8 With unspecified complications	0.000	0.655	0.345
C90 Multiple myeloma and malignant plasma cell neoplasms	0.344	0.656	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.343	0.657	0.000
E10.0 With coma	0.000	0.663	0.337
C92 Myeloid leukaemia	0.325	0.675	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.324	0.676	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.317	0.683	0.000
E10.7 With multiple complications	0.000	0.683	0.316
E10.4 With neurological complications	0.000	0.687	0.313
C90.0 Multiple myeloma	0.311	0.689	0.000
E10.6 With other specified complications	0.000	0.695	0.305
C92.0 Acute myeloid leukaemia	0.300	0.700	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.298	0.702	0.000
E10.2 With renal complications	0.000	0.711	0.289
C95 Leukaemia of unspecified cell type	0.278	0.722	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.274	0.725	0.000
C94 Other leukaemias of specified cell type	0.274	0.725	0.000
C93 Monocytic leukaemia	0.274	0.725	0.000
C86 Other specified types of T/NK-cell lymphoma	0.274	0.725	0.000
C88 Malignant immunoproliferative diseases	0.271	0.729	0.000
C43 Malignant melanoma of skin	0.270	0.730	0.000
C81 Hodgkin's disease	0.267	0.733	0.000
C90.2 Plasmacytoma, extramedullary	0.263	0.737	0.000
C90.3 Solitary plasmacytoma	0.247	0.753	0.000
C90.1 Plasma cell leukaemia	0.247	0.753	0.000
C91 Lymphoid leukaemia	0.241	0.758	0.001
C84 Peripheral and cutaneous T-cell lymphomas	0.240	0.760	0.000
C81.1 Nodular sclerosis	0.233	0.767	0.000
C92.9 Myeloid leukaemia, unspecified	0.233	0.767	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.233	0.767	0.000
C92.7 Other myeloid leukaemia	0.233	0.767	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.233	0.767	0.000
C92.5 Acute myelomonocytic leukaemia	0.233	0.767	0.000
C92.4 Acute promyelocytic leukaemia	0.233	0.767	0.000
C92.3 Myeloid sarcoma	0.233	0.767	0.000
C92.2 Subacute myeloid leukaemia	0.233	0.767	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.232	0.768	0.000
C85.0 Lymphosarcoma	0.232	0.768	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.222	0.778	0.000
E10.5 With peripheral circulatory complications	0.000	0.779	0.221
C85.1 B-cell lymphoma, unspecified	0.221	0.779	0.000
L57.0 Actinic keratosis	0.217	0.783	0.000
C43.4 Malignant melanoma of scalp and neck	0.207	0.793	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.206	0.794	0.000
C95.9 Leukaemia, unspecified	0.203	0.797	0.000
C95.7 Other leukaemia of unspecified cell type	0.199	0.800	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.199	0.800	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.199	0.800	0.000
C95.0 Acute leukaemia of unspecified cell type	0.199	0.800	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.197	0.803	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.197	0.803	0.000
C86.4 Blastic NK-cell lymphoma	0.197	0.803	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.197	0.803	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.197	0.803	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.197	0.803	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.197	0.803	0.000
C93.9 Monocytic leukaemia, unspecified	0.197	0.803	0.000
C93.7 Other monocytic leukaemia	0.197	0.803	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.197	0.803	0.000
C93.2 Subacute monocytic leukaemia	0.197	0.803	0.000
C93.1 Chronic monocytic leukaemia	0.197	0.803	0.000
C93.0 Acute monocytic leukaemia	0.197	0.803	0.000
C94.7 Other specified leukaemias	0.197	0.803	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.197	0.803	0.000
C94.5 Acute myelofibrosis	0.197	0.803	0.000
C94.4 Acute panmyelosis	0.197	0.803	0.000
C94.3 Mast cell leukaemia	0.197	0.803	0.000
C94.2 Acute megakaryoblastic leukaemia	0.197	0.803	0.000
C94.1 Chronic erythraemia	0.197	0.803	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.197	0.803	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.197	0.803	0.000
C96.8 Histiocytic sarcoma	0.197	0.803	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.197	0.803	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.197	0.803	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.197	0.803	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.197	0.803	0.000
C96.3 True histiocytic lymphoma	0.197	0.803	0.000
C96.2 Malignant mast cell tumour	0.197	0.803	0.000
C96.1 Malignant histiocytosis	0.197	0.803	0.000
C96.0 Letterer-Siwe disease	0.197	0.803	0.000
C91.0 Acute lymphoblastic leukaemia	0.196	0.803	0.001
C88.9 Malignant immunoproliferative disease, unspecified	0.194	0.806	0.000
C88.7 Other malignant immunoproliferative diseases	0.194	0.806	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.194	0.806	0.000
C88.3 Immunoproliferative small intestinal disease	0.194	0.806	0.000
C88.2 Gamma heavy chain disease	0.194	0.806	0.000
C88.1 Alpha heavy chain disease	0.194	0.806	0.000
C43.8 Overlapping malignant melanoma of skin	0.194	0.806	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.194	0.806	0.000
C43.0 Malignant melanoma of lip	0.194	0.806	0.000
C91.5 Adult T-cell leukaemia	0.192	0.808	0.001
C81.7 Other Hodgkin's disease	0.192	0.808	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.192	0.808	0.000
C81.3 Lymphocytic depletion	0.192	0.808	0.000
C81.2 Mixed cellularity	0.192	0.808	0.000
C81.0 Lymphocytic predominance	0.192	0.808	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.191	0.809	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.190	0.810	0.000
C91.9 Lymphoid leukaemia, unspecified	0.189	0.810	0.001
C85.7 Other specified types of non-Hodgkin's lymphoma	0.189	0.810	0.000
I20-I25 Ischaemic heart diseases	0.189	0.811	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.187	0.813	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.185	0.815	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.184	0.816	0.000
C92.1 Chronic myeloid leukaemia	0.177	0.822	0.000
I25 Chronic ischaemic heart disease	0.175	0.825	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.173	0.826	0.001
C91.7 Other lymphoid leukaemia	0.173	0.826	0.001
C91.6 Prolymphocytic leukaemia of T-cell type	0.173	0.826	0.001
C91.3 Prolymphocytic leukaemia	0.173	0.826	0.001
C91.2 Subacute lymphocytic leukaemia	0.173	0.826	0.001
C84.9 Mature T/NK-cell lymphoma, unspecified	0.172	0.827	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.172	0.827	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.172	0.827	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.172	0.827	0.000
C84.3 Lymphoepithelioid lymphoma	0.172	0.827	0.000
C84.2 T-zone lymphoma	0.172	0.827	0.000
C84.1 Sezary's diease	0.172	0.827	0.000
C84.0 Mycosis fungoides	0.172	0.827	0.000
I21.4 Acute subendocardial myocardial infarction	0.172	0.828	0.000
C84.5 Other and unspecified T-cell lymphomas	0.165	0.835	0.000
C91.4 Hairy-cell leukaemia	0.155	0.844	0.001
C84.4 Peripheral T-cell lymphoma	0.148	0.851	0.000
C43.5 Malignant melanoma of trunk	0.145	0.855	0.000
I25.3 Aneurysm of heart	0.140	0.860	0.000
C43.9 Malignant melanoma of skin, unspecified	0.140	0.860	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.140	0.860	0.000
I22 Subsequent myocardial infarction	0.139	0.861	0.000
D50.8 Other iron deficiency anaemias	0.000	0.863	0.137
D50 Iron deficiency anaemia	0.000	0.864	0.136
C83.7 Burkitt's tumour	0.132	0.868	0.000
C83.6 Undifferentiated (diffuse)	0.132	0.868	0.000
C83.5 Lymphoblastic (diffuse)	0.132	0.868	0.000
C83.4 Immunoblastic (diffuse)	0.132	0.868	0.000
C83.2 Mixed small and large cell (diffuse)	0.132	0.868	0.000
I23 Certain current complications following acute myocardial infarction	0.132	0.868	0.000
D50-D53 Nutritional anaemias	0.000	0.870	0.130
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.128	0.871	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.872	0.128
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.872	0.128
D50.9 Iron deficiency anaemia, unspecified	0.000	0.873	0.127
C83.3 Large cell (diffuse)	0.127	0.873	0.000
I25.6 Silent myocardial ischaemia	0.126	0.874	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.123	0.877	0.000
I25.5 Ischaemic cardiomyopathy	0.123	0.877	0.000
C83.1 Small cleaved cell (diffuse)	0.117	0.882	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.114	0.885	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.106	0.894	0.000
D86 Sarcoidosis	0.000	0.894	0.106
L57 Skin changes due to chronic exposure to nonionising radiation	0.106	0.894	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.897	0.103
D80-D89 Certain disorders involving the immune mechanism	0.000	0.899	0.101
I25.0 Atherosclerotic cardiovascular disease, so described	0.099	0.901	0.000
I25.4 Coronary artery aneurysm	0.099	0.901	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.901	0.099
D86.0 Sarcoidosis of lung	0.000	0.901	0.099
D50.1 Sideropenic dysphagia	0.000	0.902	0.097
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.095	0.905	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.095	0.905	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.095	0.905	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.095	0.905	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.095	0.905	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.095	0.905	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.095	0.905	0.000
I24 Other acute ischaemic heart diseases	0.094	0.906	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.908	0.092
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.908	0.092
D51.2 Transcobalamin II deficiency	0.000	0.908	0.092
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.908	0.092
D52 Folate deficiency anaemia	0.000	0.908	0.092
I23.8 Other current complications following acute myocardial infarction	0.091	0.909	0.000
Chapter II Neoplasms	0.091	0.909	0.000
I25.2 Old myocardial infarction	0.090	0.910	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.910	0.090
D86.8 Sarcoidosis of other and combined sites	0.000	0.911	0.089
I25.1 Atherosclerotic heart disease	0.087	0.913	0.000
C81.9 Hodgkin's disease, unspecified	0.083	0.916	0.001
D55-D59 Haemolytic anaemias	0.000	0.920	0.080
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.079	0.921	0.000
D53 Other nutritional anaemias	0.000	0.921	0.079
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.921	0.079
I22.8 Subsequent myocardial infarction of other sites	0.077	0.923	0.000
D86.3 Sarcoidosis of skin	0.000	0.924	0.076
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.924	0.076
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.924	0.076
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.076	0.924	0.000
L57.5 Actinic granuloma	0.076	0.924	0.000
L57.3 Poikiloderma of Civatte	0.076	0.924	0.000
L57.2 Cutis rhomboidalis nuchae	0.076	0.924	0.000
L57.1 Actinic reticuloid	0.076	0.924	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.924	0.076
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.926	0.074
C83.0 Small cell (diffuse)	0.073	0.926	0.001
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.073	0.927	0.000
L57.4 Cutis laxa senilis	0.073	0.927	0.000
E10-E14 Diabetes mellitus	0.000	0.927	0.073
D59 Acquired haemolytic anaemia	0.000	0.927	0.072
D83 Common variable immunodeficiency	0.000	0.928	0.072
D82 Immunodeficiency associated with other major defects	0.000	0.928	0.072
D81 Combined immunodeficiencies	0.000	0.928	0.072
I22.9 Subsequent myocardial infarction of unspecified site	0.071	0.929	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.070	0.930	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.069	0.931	0.000
I24.1 Dressler's syndrome	0.067	0.932	0.000
C73 Malignant neoplasm of thyroid gland	0.067	0.933	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.067	0.933	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.933	0.067
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.933	0.067
D68 Other coagulation defects	0.000	0.933	0.067
D52.8 Other folate deficiency anaemias	0.000	0.934	0.066
D52.1 Drug-induced folate deficiency anaemia	0.000	0.934	0.066
D52.0 Dietary folate deficiency anaemia	0.000	0.934	0.066
J45.9 Asthma, unspecified	0.000	0.934	0.066
C40-C41 Malignant neoplasms of bone and articular cartilage	0.065	0.935	0.000
D66 Hereditary factor VIII deficiency	0.000	0.935	0.065
K90-K93 Other diseases of the digestive system	0.000	0.935	0.065
I24.9 Acute ischaemic heart disease, unspecified	0.065	0.935	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.064	0.936	0.000
D84 Other immunodeficiencies	0.000	0.936	0.064
D52.9 Folate deficiency anaemia, unspecified	0.000	0.936	0.064
D80 Immunodeficiency with predominantly antibody defects	0.000	0.936	0.064
C02.1 Border of tongue	0.063	0.937	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.063	0.937	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.060	0.940	0.000
C02.9 Tongue, unspecified	0.059	0.941	0.000
D68.0 Von Willebrand's disease	0.000	0.941	0.059
C74 Malignant neoplasm of adrenal gland	0.059	0.941	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.941	0.059
I24.8 Other forms of acute ischaemic heart disease	0.058	0.942	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.058	0.942	0.000
D57 Sickle-cell disorders	0.000	0.942	0.058
D55 Anaemia due to enzyme disorders	0.000	0.942	0.058
I20 Angina pectoris	0.058	0.942	0.000
D53.8 Other specified nutritional anaemias	0.000	0.943	0.057
D53.2 Scorbutic anaemia	0.000	0.943	0.057
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.943	0.057
D53.0 Protein deficiency anaemia	0.000	0.943	0.057
C03 Malignant neoplasm of gum	0.057	0.943	0.000
D67 Hereditary factor IX deficiency	0.000	0.943	0.057
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.943	0.057
C11 Malignant neoplasm of nasopharynx	0.056	0.944	0.000
D00-D09 In situ neoplasms	0.055	0.945	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.945	0.055
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.945	0.055
D89.3 Immune reconstitution syndrome	0.000	0.945	0.055
D89.1 Cryoglobulinaemia	0.000	0.945	0.055
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.945	0.055
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.946	0.054
C13 Malignant neoplasm of hypopharynx	0.053	0.947	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.053	0.947	0.000
C05 Malignant neoplasm of palate	0.053	0.947	0.000
C04 Malignant neoplasm of floor of mouth	0.053	0.947	0.000
C00 Malignant neoplasm of lip	0.053	0.947	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.947	0.052
D59.8 Other acquired haemolytic anaemias	0.000	0.948	0.052
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.948	0.052
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.948	0.052
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.948	0.052
D59.3 Haemolytic-uraemic syndrome	0.000	0.948	0.052
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.948	0.052
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.948	0.052
D81.9 Combined immunodeficiency, unspecified	0.000	0.948	0.052
D81.8 Other combined immunodeficiencies	0.000	0.948	0.052
D81.7 Major histocompatibility complex class II deficiency	0.000	0.948	0.052
D81.6 Major histocompatibility complex class I deficiency	0.000	0.948	0.052
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.948	0.052
D81.4 Nezelof's syndrome	0.000	0.948	0.052
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.948	0.052
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.948	0.052
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.948	0.052
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.948	0.052
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.948	0.052
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.948	0.052
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.948	0.052
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.948	0.052
D82.2 Immunodeficiency with short-limbed stature	0.000	0.948	0.052
D82.1 Di George's syndrome	0.000	0.948	0.052
D82.0 Wiskott-Aldrich syndrome	0.000	0.948	0.052
D83.9 Common variable immunodeficiency, unspecified	0.000	0.948	0.052
D83.8 Other common variable immunodeficiencies	0.000	0.948	0.052
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.948	0.052
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.948	0.052
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.948	0.052
D58 Other hereditary haemolytic anaemias	0.000	0.948	0.052
C12 Malignant neoplasm of pyriform sinus	0.052	0.948	0.000
I20.1 Angina pectoris with documented spasm	0.052	0.948	0.000
C75.9 Endocrine gland, unspecified	0.051	0.948	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.948	0.051
D68.8 Other specified coagulation defects	0.000	0.949	0.051
C06.9 Mouth, unspecified	0.050	0.950	0.000
D56 Thalassaemia	0.000	0.950	0.050
C49 Malignant neoplasm of other connective and soft tissue	0.050	0.950	0.000
C02.8 Overlapping lesion of tongue	0.050	0.950	0.000
C02.4 Lingual tonsil	0.050	0.950	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.050	0.950	0.000
C02.2 Ventral surface of tongue	0.050	0.950	0.000
C02.0 Dorsal surface of tongue	0.050	0.950	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.950	0.050
C97 Malignant neoplasms of independent (primary) multiple sites	0.050	0.950	0.000
C10 Malignant neoplasm of oropharynx	0.049	0.951	0.000
D03 Melanoma in situ	0.049	0.951	0.000
D68.6 Other Thrombophilia	0.000	0.952	0.048
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.048	0.952	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.952	0.048
D68.1 Hereditary factor XI deficiency	0.000	0.952	0.048
E13 Other specified diabetes mellitus	0.000	0.952	0.048
T81.8 Other complications of procedures, not elsewhere classified	0.000	0.953	0.047
D68.5 Primary Thrombophilia	0.000	0.953	0.047
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.047	0.953	0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.047	0.953	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.047	0.953	0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.047	0.953	0.000
C09 Malignant neoplasm of tonsil	0.047	0.953	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.953	0.047
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.046	0.954	0.000
C46 Kaposi's sarcoma	0.046	0.954	0.000
D84.8 Other specified immunodeficiencies	0.000	0.954	0.046
D84.1 Defects in the complement system	0.000	0.954	0.046
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.954	0.046
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.954	0.046
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.954	0.046
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.954	0.046
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.954	0.046
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.954	0.046
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.954	0.046
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.954	0.046
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.954	0.046
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.046	0.954	0.000
C75.8 Pluriglandular involvement, unspecified	0.045	0.954	0.000
C75.5 Aortic body and other paraganglia	0.045	0.954	0.000
C75.4 Carotid body	0.045	0.954	0.000
C75.3 Pineal gland	0.045	0.954	0.000
C75.2 Craniopharyngeal duct	0.045	0.954	0.000
C75.1 Pituitary gland	0.045	0.954	0.000
C75.0 Parathyroid gland	0.045	0.954	0.000
C03.1 Lower gum	0.045	0.955	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.045	0.955	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.045	0.955	0.000
C74.9 Adrenal gland, unspecified	0.044	0.955	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.044	0.956	0.000
C11.9 Nasopharynx, unspecified	0.044	0.956	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.000	0.956	0.044
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.956	0.043
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.043	0.957	0.000
C06.2 Retromolar area	0.043	0.957	0.000
C06.1 Vestibule of mouth	0.043	0.957	0.000
C06.0 Cheek mucosa	0.043	0.957	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.043	0.957	0.000
E14 Unspecified diabetes mellitus	0.000	0.957	0.043
D53.9 Nutritional anaemia, unspecified	0.001	0.957	0.042
C74.1 Medulla of adrenal gland	0.042	0.957	0.000
C74.0 Cortex of adrenal gland	0.042	0.957	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.000	0.957	0.043
C07 Malignant neoplasm of parotid gland	0.042	0.958	0.000
C64-C68 Malignant neoplasms of urinary tract	0.042	0.958	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.958	0.041
D55.8 Other anaemias due to enzyme disorders	0.000	0.958	0.041
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.958	0.041
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.958	0.041
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.958	0.041
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.958	0.041
D57.8 Other sickle-cell disorders	0.000	0.958	0.041
D57.3 Sickle-cell trait	0.000	0.958	0.041
D57.2 Double heterozygous sickling disorders	0.000	0.958	0.041
D57.1 Sickle-cell anaemia without crisis	0.000	0.958	0.041
D57.0 Sickle-cell anaemia with crisis	0.000	0.958	0.041
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.041	0.958	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.041	0.958	0.000
D04 Carcinoma in situ of skin	0.041	0.959	0.000
C03.9 Gum, unspecified	0.041	0.959	0.000
C03.0 Upper gum	0.041	0.959	0.000
C45 Mesothelioma	0.041	0.959	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.959	0.040
C11.8 Overlapping lesion of nasopharynx	0.040	0.959	0.000
C11.3 Anterior wall of nasopharynx	0.040	0.959	0.000
C11.2 Lateral wall of nasopharynx	0.040	0.959	0.000
C11.1 Posterior wall of nasopharynx	0.040	0.959	0.000
C11.0 Superior wall of nasopharynx	0.040	0.959	0.000
D09 Carcinoma in situ of other and unspecified sites	0.040	0.959	0.000
C49.0 Connective and soft tissue of head, face and neck	0.040	0.960	0.000
C49.4 Connective and soft tissue of abdomen	0.040	0.960	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.039	0.960	0.000
C50-C50 Malignant neoplasm of breast	0.038	0.962	0.000
C00.9 Lip, unspecified	0.038	0.962	0.000
C00.8 Overlapping lesion of lip	0.038	0.962	0.000
C00.6 Commissure of lip	0.038	0.962	0.000
C00.5 Lip, unspecified, inner aspect	0.038	0.962	0.000
C00.4 Lower lip, inner aspect	0.038	0.962	0.000
C00.3 Upper lip, inner aspect	0.038	0.962	0.000
C00.2 External lip, unspecified	0.038	0.962	0.000
C00.1 External lower lip	0.038	0.962	0.000
C00.0 External upper lip	0.038	0.962	0.000
C04.9 Floor of mouth, unspecified	0.038	0.962	0.000
C04.8 Overlapping lesion of floor of mouth	0.038	0.962	0.000
C04.1 Lateral floor of mouth	0.038	0.962	0.000
C04.0 Anterior floor of mouth	0.038	0.962	0.000
C05.9 Palate, unspecified	0.038	0.962	0.000
C05.8 Overlapping lesion of palate	0.038	0.962	0.000
C05.2 Uvula	0.038	0.962	0.000
C05.1 Soft palate	0.038	0.962	0.000
C05.0 Hard palate	0.038	0.962	0.000
C08.9 Major salivary gland, unspecified	0.038	0.962	0.000
C08.8 Overlapping lesion of major salivary glands	0.038	0.962	0.000
C08.1 Sublingual gland	0.038	0.962	0.000
C08.0 Submandibular gland	0.038	0.962	0.000
C13.9 Hypopharynx, unspecified	0.038	0.962	0.000
C13.8 Overlapping lesion of hypopharynx	0.038	0.962	0.000
C13.2 Posterior wall of hypopharynx	0.038	0.962	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.038	0.962	0.000
C13.0 Postcricoid region	0.038	0.962	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.962	0.038
E12.9 Without complications	0.000	0.962	0.038
E12.8 With unspecified complications	0.000	0.962	0.038
E12.7 With multiple complications	0.000	0.962	0.038
E12.6 With other specified complications	0.000	0.962	0.038
E12.5 With peripheral circulatory complications	0.000	0.962	0.038
E12.4 With neurological complications	0.000	0.962	0.038
E12.3 With ophthalmic complications	0.000	0.962	0.038
E12.2 With renal complications	0.000	0.962	0.038
E12.1 With ketoacidosis	0.000	0.962	0.038
E12.0 With coma	0.000	0.962	0.038
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.962	0.038
D03.4 Melanoma in situ of scalp and neck	0.038	0.962	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.962	0.037
D58.2 Other haemoglobinopathies	0.000	0.962	0.037
D58.1 Hereditary elliptocytosis	0.000	0.962	0.037
D03.5 Melanoma in situ of trunk	0.037	0.962	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.037	0.962	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.963	0.037
D01.0 Colon	0.036	0.963	0.000
D56.9 Thalassaemia, unspecified	0.000	0.964	0.036
D56.8 Other thalassaemias	0.000	0.964	0.036
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.964	0.036
D56.2 Delta-beta thalassaemia	0.000	0.964	0.036
D56.0 Alpha thalassaemia	0.000	0.964	0.036
C49.8 Overlapping lesion of connective and soft tissue	0.036	0.964	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.036	0.964	0.000
C49.5 Connective and soft tissue of pelvis	0.036	0.964	0.000
J45 Asthma	0.000	0.964	0.036
C49.9 Connective and soft tissue, unspecified	0.035	0.964	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.035	0.965	0.000
C10.8 Overlapping lesion of oropharynx	0.035	0.965	0.000
C10.4 Branchial cleft	0.035	0.965	0.000
C10.3 Posterior wall of oropharynx	0.035	0.965	0.000
C10.2 Lateral wall of oropharynx	0.035	0.965	0.000
C10.1 Anterior surface of epiglottis	0.035	0.965	0.000
C10.0 Vallecula	0.035	0.965	0.000
D03.9 Melanoma in situ, unspecified	0.035	0.965	0.000
D03.8 Melanoma in situ of other sites	0.035	0.965	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.035	0.965	0.000
D03.0 Melanoma in situ of lip	0.035	0.965	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.035	0.965	0.000
C49.3 Connective and soft tissue of thorax	0.035	0.965	0.000
C65 Malignant neoplasm of renal pelvis	0.035	0.965	0.000
D04.4 Skin of scalp and neck	0.035	0.965	0.000
C01 Malignant neoplasm of base of tongue	0.035	0.965	0.000
D56.3 Thalassaemia trait	0.000	0.965	0.034
E13.8 With unspecified complications	0.000	0.966	0.034
E13.7 With multiple complications	0.000	0.966	0.034
E13.6 With other specified complications	0.000	0.966	0.034
E13.5 With peripheral circulatory complications	0.000	0.966	0.034

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations