TreeWAS – Variant ID: rs10435736

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12.4 Descending colon	0.379	0.621	0.000
D12.3 Transverse colon	0.365	0.635	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.350	0.650	0.000
D12.7 Rectosigmoid junction	0.309	0.691	0.000
D12.9 Anus and anal canal	0.290	0.710	0.000
D12.2 Ascending colon	0.236	0.764	0.000
D12.5 Sigmoid colon	0.224	0.776	0.000
D12.1 Appendix	0.221	0.779	0.000
D12.6 Colon, unspecified	0.133	0.867	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.100	0.900	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.098	0.902	0.000
D10-D36 Benign neoplasms	0.094	0.906	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.088	0.912	0.000
D21.9 Connective and other soft tissue, unspecified	0.086	0.914	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.084	0.916	0.000
D33.3 Cranial nerves	0.084	0.916	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.083	0.917	0.000
D29 Benign neoplasm of male genital organs	0.079	0.921	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.078	0.922	0.000
D30 Benign neoplasm of urinary organs	0.077	0.923	0.000
D21.5 Connective and other soft tissue of pelvis	0.077	0.923	0.000
D16 Benign neoplasm of bone and articular cartilage	0.077	0.923	0.000
D11 Benign neoplasm of major salivary glands	0.076	0.924	0.000
D34 Benign neoplasm of thyroid gland	0.075	0.925	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.075	0.925	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.072	0.928	0.000
D21.4 Connective and other soft tissue of abdomen	0.072	0.928	0.000
D21.3 Connective and other soft tissue of thorax	0.072	0.928	0.000
D24 Benign neoplasm of breast	0.072	0.928	0.000
D16.3 Short bones of lower limb	0.069	0.931	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.068	0.932	0.000
D29.1 Prostate	0.068	0.932	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.067	0.933	0.000
D19 Benign neoplasm of mesothelial tissue	0.067	0.933	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.066	0.934	0.000
D33.4 Spinal cord	0.065	0.935	0.000
D33.2 Brain, unspecified	0.065	0.935	0.000
D11.0 Parotid gland	0.065	0.935	0.000
D33.9 Central nervous system, unspecified	0.063	0.937	0.000
D33.7 Other specified parts of central nervous system	0.063	0.937	0.000
D33.1 Brain, infratentorial	0.063	0.937	0.000
D33.0 Brain, supratentorial	0.063	0.937	0.000
D30.3 Bladder	0.063	0.937	0.000
D13.2 Duodenum	0.063	0.937	0.000
D13.1 Stomach	0.063	0.937	0.000
D16.0 Scapula and long bones of upper limb	0.062	0.938	0.000
D32 Benign neoplasm of meninges	0.061	0.939	0.000
D13.9 Ill-defined sites within the digestive system	0.059	0.940	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.059	0.940	0.000
D18 Haemangioma and lymphangioma, any site	0.059	0.941	0.000
D16.4 Bones of skull and face	0.059	0.941	0.000
D11.9 Major salivary gland, unspecified	0.059	0.941	0.000
D30.0 Kidney	0.059	0.941	0.000
D29.4 Scrotum	0.059	0.941	0.000
D13.3 Other and unspecified parts of small intestine	0.059	0.941	0.000
D14.3 Bronchus and lung	0.057	0.943	0.000
D29.9 Male genital organ, unspecified	0.057	0.943	0.000
D29.7 Other male genital organs	0.057	0.943	0.000
D29.3 Epididymis	0.057	0.943	0.000
D29.2 Testis	0.057	0.943	0.000
D29.0 Penis	0.057	0.943	0.000
D10 Benign neoplasm of mouth and pharynx	0.057	0.943	0.000
D28.1 Vagina	0.056	0.944	0.000
D13.7 Endocrine pancreas	0.056	0.944	0.000
D13.6 Pancreas	0.056	0.944	0.000
D13.4 Liver	0.056	0.944	0.000
D30.9 Urinary organ, unspecified	0.056	0.944	0.000
D30.7 Other urinary organs	0.056	0.944	0.000
D30.4 Urethra	0.056	0.944	0.000
D30.2 Ureter	0.056	0.944	0.000
D30.1 Renal pelvis	0.056	0.944	0.000
D12.0 Caecum	0.055	0.944	0.000
D16.9 Bone and articular cartilage, unspecified	0.055	0.945	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.055	0.945	0.000
D16.7 Ribs, sternum and clavicle	0.055	0.945	0.000
D16.6 Vertebral column	0.055	0.945	0.000
D14.4 Respiratory system, unspecified	0.054	0.946	0.000
D14.2 Trachea	0.054	0.946	0.000
D14.1 Larynx	0.052	0.948	0.000
D26 Other benign neoplasms of uterus	0.052	0.948	0.000
D13.5 Extrahepatic bile ducts	0.052	0.948	0.000
D16.5 Lower jaw bone	0.051	0.949	0.000
D15.0 Thymus	0.050	0.950	0.000
D15.9 Intrathoracic organ, unspecified	0.049	0.951	0.000
D15.7 Other specified intrathoracic organs	0.049	0.951	0.000
D15.2 Mediastinum	0.049	0.951	0.000
D15.1 Heart	0.049	0.951	0.000
D19.9 Mesothelial tissue, unspecified	0.048	0.951	0.000
D19.7 Mesothelial tissue of other sites	0.048	0.951	0.000
D19.1 Mesothelial tissue of peritoneum	0.048	0.951	0.000
D19.0 Mesothelial tissue of pleura	0.048	0.951	0.000
D20.1 Peritoneum	0.048	0.951	0.000
D20.0 Retroperitoneum	0.048	0.951	0.000
D13.0 Oesophagus	0.048	0.952	0.000
D16.2 Long bones of lower limb	0.048	0.952	0.000
D11.7 Other major salivary glands	0.048	0.952	0.000
D28.2 Uterine tubes and ligaments	0.048	0.952	0.000
D28.9 Female genital organ, unspecified	0.047	0.953	0.000
D28.7 Other specified female genital organs	0.047	0.953	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.047	0.953	0.000
D10.1 Tongue	0.047	0.953	0.000
D31 Benign neoplasm of eye and adnexa	0.046	0.953	0.000
D32.1 Spinal meninges	0.045	0.955	0.000
D18.1 Lymphangioma, any site	0.043	0.957	0.000
D16.1 Short bones of upper limb	0.042	0.957	0.000
D32.0 Cerebral meninges	0.042	0.958	0.000
D26.0 Cervix uteri	0.042	0.958	0.000
D10.9 Pharynx, unspecified	0.041	0.959	0.000
D10.7 Hypopharynx	0.041	0.959	0.000
D10.6 Nasopharynx	0.041	0.959	0.000
D10.5 Other parts of oropharynx	0.041	0.959	0.000
D10.4 Tonsil	0.041	0.959	0.000
D10.2 Floor of mouth	0.041	0.959	0.000
D35.0 Adrenal gland	0.040	0.960	0.000
D32.9 Meninges, unspecified	0.038	0.962	0.000
D26.7 Other parts of uterus	0.037	0.962	0.000
D22 Melanocytic naevi	0.035	0.965	0.000
D35.9 Endocrine gland, unspecified	0.034	0.966	0.000
D35.8 Pluriglandular involvement	0.034	0.966	0.000
D35.7 Other specified endocrine glands	0.034	0.966	0.000
D35.6 Aortic body and other paraganglia	0.034	0.966	0.000
D35.5 Carotid body	0.034	0.966	0.000
D35.4 Pineal gland	0.034	0.966	0.000
D35.3 Craniopharyngeal duct	0.034	0.966	0.000
D18.0 Haemangioma, any site	0.034	0.966	0.000
D31.9 Eye, unspecified	0.033	0.966	0.000
D31.6 Orbit, unspecified	0.033	0.966	0.000
D31.5 Lachrymal gland and duct	0.033	0.966	0.000
D31.4 Ciliary body	0.033	0.966	0.000
D31.2 Retina	0.033	0.966	0.000
D31.1 Cornea	0.033	0.966	0.000
D22.4 Melanocytic naevi of scalp and neck	0.033	0.967	0.000
D26.9 Uterus, unspecified	0.032	0.968	0.000
D10.0 Lip	0.031	0.968	0.000
D10.3 Other and unspecified parts of mouth	0.030	0.970	0.000
D36 Benign neoplasm of other and unspecified sites	0.029	0.971	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.029	0.971	0.000
D22.0 Melanocytic naevi of lip	0.028	0.972	0.000
D31.0 Conjunctiva	0.026	0.973	0.001
D28.0 Vulva	0.026	0.973	0.001
D22.2 Melanocytic naevi of ear and external auricular canal	0.027	0.973	0.000
D31.3 Choroid	0.024	0.976	0.001
D22.3 Melanocytic naevi of other and unspecified parts of face	0.023	0.977	0.000
D35.2 Pituitary gland	0.022	0.978	0.000
D26.1 Corpus uteri	0.022	0.978	0.000
D36.9 Benign neoplasm of unspecified site	0.021	0.979	0.000
D22.9 Melanocytic naevi, unspecified	0.020	0.980	0.000
D36.0 Lymph nodes	0.018	0.982	0.000
D35.1 Parathyroid gland	0.016	0.983	0.000
R47.8 Other and unspecified speech disturbances	0.016	0.984	0.000
Z91.6 Personal history of other physical trauma	0.000	0.987	0.013
D36.7 Other specified sites	0.013	0.987	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.012	0.987	0.000
D27 Benign neoplasm of ovary	0.012	0.988	0.000
D12.8 Rectum	0.012	0.988	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.012	0.988	0.000
G35 Multiple sclerosis	0.011	0.989	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.011	0.989	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.990	0.010
D22.5 Melanocytic naevi of trunk	0.008	0.992	0.000
D59.1 Other autoimmune haemolytic anaemias	0.008	0.992	0.000
D25 Leiomyoma of uterus	0.008	0.992	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.992	0.008
R47 Speech disturbances, not elsewhere classified	0.007	0.993	0.000
D75.2 Essential thrombocytosis	0.007	0.993	0.000
O34.4 Maternal care for other abnormalities of cervix	0.000	0.993	0.007
D59 Acquired haemolytic anaemia	0.007	0.993	0.000
D75 Other diseases of blood and blood-forming organs	0.007	0.993	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.994	0.006
O34.1 Maternal care for tumour of corpus uteri	0.000	0.994	0.006
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.994	0.006
E83.5 Disorders of calcium metabolism	0.000	0.994	0.006
D89.2 Hypergammaglobulinaemia, unspecified	0.006	0.994	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.006	0.994	0.000
O34.3 Maternal care for cervical incompetence	0.000	0.994	0.006
D75.1 Secondary polycythaemia	0.006	0.994	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.006	0.994	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.994	0.006
O34.6 Maternal care for abnormality of vagina	0.000	0.994	0.006
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.994	0.006
O34.0 Maternal care for congenital malformation of uterus	0.000	0.994	0.006
R47.1 Dysarthria and anarthria	0.006	0.994	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.006	0.994	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.005	0.995	0.000
D55-D59 Haemolytic anaemias	0.005	0.995	0.000
D59.8 Other acquired haemolytic anaemias	0.005	0.995	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.005	0.995	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.005	0.995	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.005	0.995	0.000
D59.3 Haemolytic-uraemic syndrome	0.005	0.995	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.005	0.995	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.005	0.995	0.000
D80-D89 Certain disorders involving the immune mechanism	0.005	0.995	0.000
D80 Immunodeficiency with predominantly antibody defects	0.005	0.995	0.000
R06.5 Mouth breathing	0.000	0.995	0.005
D73.0 Hyposplenism	0.005	0.995	0.000
D25.2 Subserosal leiomyoma of uterus	0.005	0.995	0.000
L40.9 Psoriasis, unspecified	0.000	0.995	0.005
D84 Other immunodeficiencies	0.005	0.995	0.000
D73 Diseases of spleen	0.005	0.995	0.000
R47.0 Dysphasia and aphasia	0.005	0.995	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.005	0.995	0.000
D75.0 Familial erythrocytosis	0.005	0.995	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.995	0.005
D58 Other hereditary haemolytic anaemias	0.004	0.995	0.000
D84.9 Immunodeficiency, unspecified	0.004	0.995	0.000
R04.2 Haemoptysis	0.000	0.995	0.005
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.004	0.996	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
N13.6 Pyonephrosis	0.000	0.996	0.004
D56 Thalassaemia	0.004	0.996	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.004	0.996	0.000
M65.34 Trigger finger-Hand	0.000	0.996	0.004
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
D83 Common variable immunodeficiency	0.004	0.996	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.004	0.996	0.000
D57 Sickle-cell disorders	0.004	0.996	0.000
D55 Anaemia due to enzyme disorders	0.004	0.996	0.000
K86.3 Pseudocyst of pancreas	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.004	0.996	0.000
D82 Immunodeficiency associated with other major defects	0.004	0.996	0.000
D81 Combined immunodeficiencies	0.004	0.996	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.996	0.004
D84.1 Defects in the complement system	0.004	0.996	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.004	0.996	0.000
D73.8 Other diseases of spleen	0.004	0.996	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.004	0.996	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.004	0.996	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.004	0.996	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.004	0.996	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.004	0.996	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.004	0.996	0.000
N13 Obstructive and reflux uropathy	0.000	0.996	0.004
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.004	0.996	0.000
O70.0 First degree perineal laceration during delivery	0.000	0.996	0.004
N13.8 Other obstructive and reflux uropathy	0.000	0.996	0.004
D84.8 Other specified immunodeficiencies	0.004	0.996	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.004	0.996	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996	0.000
D73.9 Disease of spleen, unspecified	0.004	0.996	0.000
D73.4 Cyst of spleen	0.004	0.996	0.000
D73.3 Abscess of spleen	0.004	0.996	0.000
D73.2 Chronic congestive splenomegaly	0.004	0.996	0.000
D73.1 Hypersplenism	0.004	0.996	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.996	0.004
D76.3 Other histiocytosis syndromes	0.004	0.996	0.000
E83.1 Disorders of iron metabolism	0.000	0.996	0.004
D74 Methaemoglobinaemia	0.004	0.996	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.004	0.996	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.004	0.996	0.000
D56.1 Beta thalassaemia	0.003	0.996	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.996	0.004
K05.3 Chronic periodontitis	0.000	0.996	0.004
D58.8 Other specified hereditary haemolytic anaemias	0.003	0.996	0.000
D58.2 Other haemoglobinopathies	0.003	0.996	0.000
D58.1 Hereditary elliptocytosis	0.003	0.996	0.000
D58.0 Hereditary spherocytosis	0.003	0.996	0.000
D73.5 Infarction of spleen	0.003	0.996	0.000
E83 Disorders of mineral metabolism	0.000	0.996	0.004
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.996	0.004
D83.9 Common variable immunodeficiency, unspecified	0.003	0.996	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.000	0.997	0.003
D56.9 Thalassaemia, unspecified	0.003	0.997	0.000
D56.8 Other thalassaemias	0.003	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.003	0.997	0.000
D56.2 Delta-beta thalassaemia	0.003	0.997	0.000
D56.0 Alpha thalassaemia	0.003	0.997	0.000
D83.8 Other common variable immunodeficiencies	0.003	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.997	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.997	0.003
D55.9 Anaemia due to enzyme disorder, unspecified	0.003	0.997	0.000
D55.8 Other anaemias due to enzyme disorders	0.003	0.997	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.003	0.997	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.003	0.997	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.003	0.997	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.003	0.997	0.000
D57.8 Other sickle-cell disorders	0.003	0.997	0.000
D57.3 Sickle-cell trait	0.003	0.997	0.000
D57.2 Double heterozygous sickling disorders	0.003	0.997	0.000
D57.1 Sickle-cell anaemia without crisis	0.003	0.997	0.000
D57.0 Sickle-cell anaemia with crisis	0.003	0.997	0.000
G36 Other acute disseminated demyelination	0.003	0.997	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.997	0.003
D76.2 Haemophagocytic syndrome, infection-associated	0.003	0.997	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.003	0.997	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.003	0.997	0.000
D81.9 Combined immunodeficiency, unspecified	0.003	0.997	0.000
D81.8 Other combined immunodeficiencies	0.003	0.997	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.997	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.997	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.997	0.000
D81.4 Nezelof's syndrome	0.003	0.997	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.997	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.997	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.997	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.997	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.997	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.997	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.997	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.997	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.997	0.000
D82.1 Di George's syndrome	0.003	0.997	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.997	0.000
D56.3 Thalassaemia trait	0.003	0.997	0.000
D25.0 Submucous leiomyoma of uterus	0.003	0.997	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.000	0.997	0.003
R41.3 Other amnesia	0.003	0.997	0.000
D74.9 Methaemoglobinaemia, unspecified	0.003	0.997	0.000
D74.8 Other methaemoglobinaemias	0.003	0.997	0.000
D74.0 Congenital methaemoglobinaemia	0.003	0.997	0.000
G37 Other demyelinating diseases of central nervous system	0.003	0.997	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.997	0.003
E83.8 Other disorders of mineral metabolism	0.000	0.997	0.003
E83.2 Disorders of zinc metabolism	0.000	0.997	0.003
E83.0 Disorders of copper metabolism	0.000	0.997	0.003
D86 Sarcoidosis	0.003	0.997	0.000
L72.0 Epidermal cyst	0.000	0.997	0.003
M18.1 Other primary arthrosis of first carpometacarpal joint	0.003	0.997	0.000
R41.0 Disorientation, unspecified	0.003	0.997	0.000
Z97.4 Presence of external hearing-aid	0.000	0.997	0.003
D25.1 Intramural leiomyoma of uterus	0.003	0.997	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.997	0.003
Z91.7 Personal history of female genital mutilation	0.000	0.997	0.003
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.000	0.997	0.003
Z91.3 Personal history of unhealthy sleep-wake schedule	0.000	0.997	0.003
Z91.2 Personal history of poor personal hygiene	0.000	0.997	0.003
M65.3 Trigger finger	0.000	0.997	0.003
G36.9 Acute disseminated demyelination, unspecified	0.002	0.997	0.000
G36.8 Other specified acute disseminated demyelination	0.002	0.997	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.002	0.997	0.000
G36.0 Neuromyelitis optica [Devic]	0.002	0.997	0.000
S51.9 Open wound of forearm, part unspecified	0.003	0.997	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.997	0.003
S51.8 Open wound of other parts of forearm	0.003	0.997	0.000
O70.2 Third degree perineal laceration during delivery	0.000	0.997	0.002
D72 Other disorders of white blood cells	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
R04.0 Epistaxis	0.000	0.998	0.002
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
G37.5 Concentric sclerosis [Balo]	0.002	0.998	0.000
G37.4 Subacute necrotising myelitis	0.002	0.998	0.000
G37.2 Central pontine myelinolysis	0.002	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.002	0.998	0.000
G37.0 Diffuse sclerosis	0.002	0.998	0.000
R04 Haemorrhage from respiratory passages	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
D23.4 Skin of scalp and neck	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
G93.6 Cerebral oedema	0.002	0.998	0.000
S51 Open wound of forearm	0.002	0.998	0.000
M65.39 Trigger finger-Site unspec	0.000	0.998	0.002
M65.38 Trigger finger-Other	0.000	0.998	0.002
M65.37 Trigger finger-Ankle/foot	0.000	0.998	0.002
M65.36 Trigger finger-Lower leg	0.000	0.998	0.002
M65.35 Trigger finger-Pelvic/thigh	0.000	0.998	0.002
M65.33 Trigger finger-Forearm	0.000	0.998	0.002
M65.32 Trigger finger-Upper arm	0.000	0.998	0.002
M65.31 Trigger finger-Shldr region	0.000	0.998	0.002
M65.30 Trigger finger-Mult sites	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
C44.2 Skin of ear and external auricular canal	0.002	0.998	0.000
G93.4 Encephalopathy, unspecified	0.002	0.998	0.000
G93.9 Disorder of brain, unspecified	0.002	0.998	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.002	0.998	0.000
R47-R49 Symptoms and signs involving speech and voice	0.002	0.998	0.000
S62.61 Fracture of other finger (open)	0.002	0.998	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.002	0.998	0.000
D23.5 Skin of trunk	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.002	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.998	0.002
E83.4 Disorders of magnesium metabolism	0.000	0.998	0.002
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.998	0.002
R04.9 Haemorrhage from respiratory passages, unspecified	0.000	0.998	0.002
R04.1 Haemorrhage from throat	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
G93 Other disorders of brain	0.002	0.998	0.000
G93.8 Other specified disorders of brain	0.002	0.998	0.000
N13.4 Hydroureter	0.000	0.998	0.002
S51.7 Multiple open wounds of forearm	0.002	0.998	0.000
R41.2 Retrograde amnesia	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.002	0.998	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.998	0.002
D72.1 Eosinophilia	0.001	0.998	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.998	0.002
D23.0 Skin of lip	0.000	0.998	0.002
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
G93.0 Cerebral cysts	0.002	0.998	0.000
R41.1 Anterograde amnesia	0.002	0.998	0.000
O70 Perineal laceration during delivery	0.000	0.998	0.002
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.998	0.002
G93.2 Benign intracranial hypertension	0.002	0.998	0.000
D23 Other benign neoplasms of skin	0.000	0.998	0.002
J81 Pulmonary oedema	0.002	0.998	0.000
G93.5 Compression of brain	0.002	0.998	0.000
N26 Unspecified contracted kidney	0.000	0.998	0.002
S51.0 Open wound of elbow	0.002	0.998	0.000
L40 Psoriasis	0.000	0.998	0.002
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.998	0.002
G93.7 Reye's syndrome	0.001	0.998	0.000
H52.2 Astigmatism	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.002
N92.3 Ovulation bleeding	0.002	0.998	0.000
D23.9 Skin, unspecified	0.000	0.998	0.001
R04.8 Haemorrhage from other sites in respiratory passages	0.000	0.998	0.001
R48.8 Other and unspecified symbolic dysfunctions	0.001	0.998	0.000
R48.2 Apraxia	0.001	0.998	0.000
R48.1 Agnosia	0.001	0.998	0.000
R48.0 Dyslexia and alexia	0.001	0.998	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.998	0.002
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.998	0.001
D23.7 Skin of lower limb, including hip	0.000	0.998	0.002
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.000	0.998	0.001
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.000	0.998	0.001
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.000	0.998	0.001
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.000	0.998	0.001
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.000	0.998	0.001
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.000	0.998	0.001
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.000	0.998	0.001
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.000	0.998	0.001
L71.9 Rosacea, unspecified	0.002	0.998	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.998	0.002
N48.6 Balanitis xerotica obliterans	0.000	0.998	0.002
O70.3 Fourth degree perineal laceration during delivery	0.000	0.998	0.001
R90.0 Intracranial space-occupying lesion	0.001	0.998	0.000
D17 Benign lipomatous neoplasm	0.002	0.998	0.000
Z97 Presence of other devices	0.000	0.998	0.002
S62.60 Fracture of other finger (closed)	0.001	0.998	0.000
H49.2 Sixth [abducent] nerve palsy	0.001	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.001	0.999	0.000
U89.8 Agent resistant to other single specified antibiotic	0.001	0.999	0.000
L40.4 Guttate psoriasis	0.000	0.999	0.001
L40.3 Pustulosis palmaris et plantaris	0.000	0.999	0.001
L40.2 Acrodermatitis continua	0.000	0.999	0.001
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.001	0.999	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.001	0.999	0.000
O00.1 Tubal pregnancy	0.001	0.999	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.001	0.999	0.000
K81.9 Cholecystitis, unspecified	0.001	0.999	0.000
L40.8 Other psoriasis	0.000	0.999	0.001
Z71.2 Person consulting for explanation of investigation findings	0.001	0.999	0.000
M65 Synovitis and tenosynovitis	0.000	0.999	0.001
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
J95.8 Other postprocedural respiratory disorders	0.000	0.999	0.001
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
S62.6 Fracture of other finger	0.001	0.999	0.000
Z71.6 Tobacco abuse counselling	0.001	0.999	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.001	0.999	0.000
M54.29 Cervicalgia-Site unspe	0.000	0.999	0.001
H20.9 Iridocyclitis, unspecified	0.000	0.999	0.001
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.999	0.001
Z71.1 Person with feared complaint in whom no diagnosis is made	0.001	0.999	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.001	0.999	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.999	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.001	0.999	0.000
M65.1 Other infective (teno)synovitis	0.000	0.999	0.001
D72.8 Other specified disorders of white blood cells	0.001	0.999	0.000
E22.1 Hyperprolactinaemia	0.001	0.999	0.000
S52.01 Fracture of upper end of ulna (open)	0.001	0.999	0.000
C16.9 Stomach, unspecified	0.001	0.999	0.000
D23.2 Skin of ear and external auricular canal	0.000	0.999	0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.999	0.000
K38.8 Other specified diseases of appendix	0.001	0.999	0.000
L40.1 Generalised pustular psoriasis	0.000	0.999	0.001
B00.5 Herpesviral ocular disease	0.001	0.999	0.000
E06.3 Autoimmune thyroiditis	0.001	0.999	0.000
M65.2 Calcific tendinitis	0.000	0.999	0.001
M65.0 Abscess of tendon sheath	0.000	0.999	0.001
R25 Abnormal involuntary movements	0.001	0.999	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.001	0.999	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.000	0.999	0.001
M66.2 Spontaneous rupture of extensor tendons	0.000	0.999	0.001
I69.1 Sequelae of intracerebral haemorrhage	0.001	0.999	0.000
K86.1 Other chronic pancreatitis	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations