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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1044043
log Bayes Factor = 38.2815
Chromosome 6   position 32,793,981  (GRCh37) Explore rs1044043 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.996 0.004 0.000
G37 Other demyelinating diseases of central nervous system
0.995 0.005 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.993 0.007 0.000
E03 Other hypothyroidism
0.000 0.054 0.946
G37.8 Other specified demyelinating diseases of central nervous system
0.891 0.109 0.000
E03.8 Other specified hypothyroidism
0.000 0.149 0.851
E00-E07 Disorders of thyroid gland
0.000 0.152 0.848
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.212 0.788
G36 Other acute disseminated demyelination
0.779 0.221 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.234 0.766
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.765 0.234 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.240 0.760
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.254 0.746
E23 Hypofunction and other disorders of pituitary gland
0.000 0.267 0.733
G37.5 Concentric sclerosis [Balo]
0.714 0.286 0.000
G37.4 Subacute necrotising myelitis
0.714 0.286 0.000
G37.2 Central pontine myelinolysis
0.714 0.286 0.000
G37.1 Central demyelination of corpus callosum
0.714 0.286 0.000
G37.0 Diffuse sclerosis
0.714 0.286 0.000
E21.0 Primary hyperparathyroidism
0.000 0.287 0.713
E05.9 Thyrotoxicosis, unspecified
0.000 0.288 0.712
E06 Thyroiditis
0.000 0.292 0.708
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.295 0.705
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.298 0.702
E24 Cushing's syndrome
0.000 0.309 0.691
E83.1 Disorders of iron metabolism
0.679 0.320 0.000
E03.5 Myxoedema coma
0.000 0.322 0.678
E03.4 Atrophy of thyroid (acquired)
0.000 0.322 0.678
E03.3 Postinfectious hypothyroidism
0.000 0.322 0.678
E03.1 Congenital hypothyroidism without goitre
0.000 0.322 0.678
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.349 0.651
E23.6 Other disorders of pituitary gland
0.000 0.350 0.650
E21.3 Hyperparathyroidism, unspecified
0.000 0.353 0.647
E23.2 Diabetes insipidus
0.000 0.362 0.637
E10-E14 Diabetes mellitus
0.000 0.363 0.637
E06.3 Autoimmune thyroiditis
0.000 0.364 0.636
E23.7 Disorder of pituitary gland, unspecified
0.000 0.369 0.631
G36.0 Neuromyelitis optica [Devic]
0.623 0.377 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.385 0.615
E24.9 Cushing's syndrome, unspecified
0.000 0.386 0.613
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.392 0.608
E00 Congenital iodine-deficiency syndrome
0.000 0.392 0.608
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.398 0.601
E05.8 Other thyrotoxicosis
0.000 0.424 0.576
E24.2 Drug-induced Cushing's syndrome
0.000 0.431 0.568
E16 Other disorders of pancreatic internal secretion
0.000 0.432 0.568
E05.5 Thyroid crisis or storm
0.000 0.435 0.565
E05.4 Thyrotoxicosis factitia
0.000 0.435 0.565
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.435 0.565
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.435 0.565
G36.9 Acute disseminated demyelination, unspecified
0.558 0.441 0.000
G36.8 Other specified acute disseminated demyelination
0.558 0.441 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.558 0.441 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.447 0.553
E28 Ovarian dysfunction
0.000 0.448 0.552
E26 Hyperaldosteronism
0.000 0.448 0.552
E25 Adrenogenital disorders
0.000 0.449 0.551
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.455 0.545
E32 Diseases of thymus
0.000 0.455 0.545
E31 Polyglandular dysfunction
0.000 0.455 0.545
E30 Disorders of puberty, not elsewhere classified
0.000 0.455 0.545
E70-E90 Metabolic disorders
0.000 0.456 0.544
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.457 0.543
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.459 0.541
E78.0 Pure hypercholesterolaemia
0.000 0.460 0.540
E29 Testicular dysfunction
0.000 0.462 0.538
E21.4 Other specified disorders of parathyroid gland
0.000 0.465 0.535
E21.2 Other hyperparathyroidism
0.000 0.465 0.535
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.467 0.533
E06.9 Thyroiditis, unspecified
0.000 0.468 0.532
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.474 0.526
E23.1 Drug-induced hypopituitarism
0.000 0.474 0.526
E23.0 Hypopituitarism
0.000 0.475 0.525
E10.3 With ophthalmic complications
0.000 0.489 0.511
E06.4 Drug-induced thyroiditis
0.000 0.492 0.507
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.492 0.507
E06.0 Acute thyroiditis
0.000 0.492 0.507
E11 Non-insulin-dependent diabetes mellitus
0.000 0.493 0.507
E13 Other specified diabetes mellitus
0.000 0.500 0.500
E24.8 Other Cushing's syndrome
0.000 0.504 0.496
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.504 0.496
E24.3 Ectopic ACTH syndrome
0.000 0.504 0.496
E24.1 Nelson's syndrome
0.000 0.504 0.496
E24.0 Pituitary-dependent Cushing's disease
0.000 0.504 0.496
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.507 0.493
E06.5 Other chronic thyroiditis
0.000 0.521 0.479
E40-E46 Malnutrition
0.000 0.524 0.476
E16.1 Other hypoglycaemia
0.000 0.524 0.475
E78.5 Hyperlipidaemia, unspecified
0.000 0.531 0.469
E15 Nondiabetic hypoglycaemic coma
0.000 0.533 0.467
E12 Malnutrition-related diabetes mellitus
0.000 0.543 0.457
E20 Hypoparathyroidism
0.000 0.548 0.451
E28.2 Polycystic ovarian syndrome
0.000 0.549 0.451
E85 Amyloidosis
0.000 0.554 0.446
E78.1 Pure hyperglyceridaemia
0.000 0.558 0.442
E10.0 With coma
0.000 0.558 0.442
E34 Other endocrine disorders
0.000 0.561 0.439
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.564 0.436
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.564 0.436
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.564 0.436
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.564 0.436
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.564 0.436
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.564 0.436
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.564 0.436
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.564 0.436
E11.6 With other specified complications
0.000 0.564 0.436
E78.6 Lipoprotein deficiency
0.000 0.568 0.432
E06.1 Subacute thyroiditis
0.000 0.571 0.429
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.571 0.429
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.572 0.428
E07 Other disorders of thyroid
0.000 0.574 0.425
E11.2 With renal complications
0.000 0.576 0.424
E10.6 With other specified complications
0.000 0.577 0.423
E11.9 Without complications
0.000 0.579 0.421
E10.5 With peripheral circulatory complications
0.000 0.583 0.417
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.592 0.407
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.592 0.407
E16.4 Abnormal secretion of gastrin
0.000 0.592 0.407
E16.3 Increased secretion of glucagon
0.000 0.592 0.407
E26.0 Primary hyperaldosteronism
0.000 0.597 0.403
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.598 0.401
E13.9 Without complications
0.000 0.599 0.401
E88 Other metabolic disorders
0.000 0.602 0.398
E10.7 With multiple complications
0.000 0.603 0.397
E28.9 Ovarian dysfunction, unspecified
0.000 0.604 0.396
E28.8 Other ovarian dysfunction
0.000 0.604 0.396
E28.1 Androgen excess
0.000 0.604 0.396
E28.0 Oestrogen excess
0.000 0.604 0.396
E26.9 Hyperaldosteronism, unspecified
0.000 0.604 0.396
E26.8 Other hyperaldosteronism
0.000 0.604 0.396
E26.1 Secondary hyperaldosteronism
0.000 0.604 0.396
E25.9 Adrenogenital disorder, unspecified
0.000 0.605 0.395
E25.8 Other adrenogenital disorders
0.000 0.605 0.395
E11.1 With ketoacidosis
0.000 0.607 0.393
E30.9 Disorder of puberty, unspecified
0.000 0.609 0.391
E30.8 Other disorders of puberty
0.000 0.609 0.391
E30.1 Precocious puberty
0.000 0.609 0.391
E30.0 Delayed puberty
0.000 0.609 0.391
E31.9 Polyglandular dysfunction, unspecified
0.000 0.609 0.391
E31.8 Other polyglandular dysfunction
0.000 0.609 0.391
E31.1 Polyglandular hyperfunction
0.000 0.609 0.391
E31.0 Autoimmune polyglandular failure
0.000 0.609 0.391
E32.9 Disease of thymus, unspecified
0.000 0.609 0.391
E32.8 Other diseases of thymus
0.000 0.609 0.391
E32.1 Abscess of thymus
0.000 0.609 0.391
E32.0 Persistent hyperplasia of thymus
0.000 0.609 0.391
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.609 0.391
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.609 0.391
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.609 0.391
E84 Cystic fibrosis
0.000 0.610 0.390
E77 Disorders of glycoprotein metabolism
0.000 0.610 0.390
E76 Disorders of glycosaminoglycan metabolism
0.000 0.610 0.390
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.610 0.390
E72 Other disorders of amino-acid metabolism
0.000 0.610 0.390
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.610 0.390
E70 Disorders of aromatic amino-acid metabolism
0.000 0.610 0.390
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.610 0.390
E10.2 With renal complications
0.000 0.610 0.390
E10.8 With unspecified complications
0.000 0.613 0.387
E29.9 Testicular dysfunction, unspecified
0.000 0.614 0.386
E29.8 Other testicular dysfunction
0.000 0.614 0.386
E29.0 Testicular hyperfunction
0.000 0.614 0.386
E85.9 Amyloidosis, unspecified
0.000 0.619 0.381
E79 Disorders of purine and pyrimidine metabolism
0.000 0.619 0.381
E29.1 Testicular hypofunction
0.000 0.621 0.379
E78.8 Other disorders of lipoprotein metabolism
0.000 0.624 0.376
E65-E68 Obesity and other hyperalimentation
0.000 0.627 0.373
E74 Other disorders of carbohydrate metabolism
0.000 0.628 0.372
E11.8 With unspecified complications
0.000 0.632 0.367
E11.7 With multiple complications
0.000 0.636 0.364
E78.4 Other hyperlipidaemia
0.000 0.637 0.363
E78.2 Mixed hyperlipidaemia
0.000 0.641 0.359
E13.8 With unspecified complications
0.000 0.642 0.358
E13.7 With multiple complications
0.000 0.642 0.358
E13.6 With other specified complications
0.000 0.642 0.358
E13.5 With peripheral circulatory complications
0.000 0.642 0.358
E13.4 With neurological complications
0.000 0.642 0.358
E13.3 With ophthalmic complications
0.000 0.642 0.358
E13.2 With renal complications
0.000 0.642 0.358
E13.1 With ketoacidosis
0.000 0.642 0.358
E13.0 With coma
0.000 0.642 0.358
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.644 0.356
E10.4 With neurological complications
0.000 0.650 0.350
E80.4 Gilbert's syndrome
0.000 0.652 0.348
E16.2 Hypoglycaemia, unspecified
0.000 0.652 0.348
E11.5 With peripheral circulatory complications
0.000 0.654 0.346
E10.9 Without complications
0.000 0.657 0.343
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.659 0.341
E45 Retarded development following protein-energy malnutrition
0.000 0.659 0.341
E43 Unspecified severe protein-energy malnutrition
0.000 0.659 0.341
E42 Marasmic kwashiorkor
0.000 0.659 0.341
E41 Nutritional marasmus
0.000 0.659 0.341
E40 Kwashiorkor
0.000 0.659 0.341
E78.3 Hyperchylomicronaemia
0.000 0.663 0.337
E11.3 With ophthalmic complications
0.000 0.666 0.334
E10.1 With ketoacidosis
0.000 0.668 0.332
E12.9 Without complications
0.000 0.672 0.328
E12.8 With unspecified complications
0.000 0.672 0.328
E12.7 With multiple complications
0.000 0.672 0.328
E12.6 With other specified complications
0.000 0.672 0.328
E12.5 With peripheral circulatory complications
0.000 0.672 0.328
E12.4 With neurological complications
0.000 0.672 0.328
E12.3 With ophthalmic complications
0.000 0.672 0.328
E12.2 With renal complications
0.000 0.672 0.328
E12.1 With ketoacidosis
0.000 0.672 0.328
E12.0 With coma
0.000 0.672 0.328
E20.8 Other hypoparathyroidism
0.000 0.676 0.324
E20.1 Pseudohypoparathyroidism
0.000 0.676 0.324
E20.0 Idiopathic hypoparathyroidism
0.000 0.676 0.324
E11.0 With coma
0.000 0.677 0.323
E28.3 Primary ovarian failure
0.000 0.677 0.323
E85.8 Other amyloidosis
0.000 0.680 0.320
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.680 0.320
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.680 0.320
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.680 0.320
E85.3 Secondary systemic amyloidosis
0.000 0.681 0.319
E34.5 Androgen resistance syndrome
0.000 0.685 0.314
E34.4 Constitutional tall stature
0.000 0.685 0.314
E34.3 Short stature, not elsewhere classified
0.000 0.685 0.314
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.685 0.314
E34.1 Other hypersecretion of intestinal hormones
0.000 0.685 0.314
E80.6 Other disorders of bilirubin metabolism
0.000 0.686 0.314
E85.4 Organ-limited amyloidosis
0.000 0.690 0.310
E07.8 Other specified disorders of thyroid
0.000 0.692 0.308
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.692 0.307
E80.5 Crigler-Najjar syndrome
0.000 0.692 0.307
E80.3 Defects of catalase and peroxydase
0.000 0.692 0.307
E80.2 Other porphyria
0.000 0.692 0.307
E80.0 Hereditary erythropoietic porphyria
0.000 0.692 0.307
E88.2 Lipomatosis, not elsewhere classified
0.000 0.694 0.306
E34.8 Other specified endocrine disorders
0.000 0.695 0.305
E07.1 Dyshormogenetic goitre
0.000 0.695 0.305
E07.0 Hypersecretion of calcitonin
0.000 0.695 0.305
E27 Other disorders of adrenal gland
0.000 0.695 0.305
L40.5 Arthropathic psoriasis
0.000 0.702 0.298
E80.1 Porphyria cutanea tarda
0.000 0.703 0.297
E73 Lactose intolerance
0.000 0.705 0.294
L40 Psoriasis
0.000 0.710 0.290
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.712 0.288
E88.9 Metabolic disorder, unspecified
0.000 0.714 0.285
E88.8 Other specified metabolic disorders
0.000 0.714 0.285
E88.3 Tumour lysis syndrome
0.000 0.714 0.285
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.720 0.280
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.720 0.280
E70.3 Albinism
0.000 0.720 0.280
E70.2 Disorders of tyrosine metabolism
0.000 0.720 0.280
E70.1 Other hyperphenylalaninaemias
0.000 0.720 0.280
E70.0 Classical phenylketonuria
0.000 0.720 0.280
E71.3 Disorders of fatty-acid metabolism
0.000 0.720 0.280
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.720 0.280
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.720 0.280
E71.0 Maple-syrup-urine disease
0.000 0.720 0.280
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.720 0.280
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.720 0.280
E72.5 Disorders of glycine metabolism
0.000 0.720 0.280
E72.4 Disorders of ornithine metabolism
0.000 0.720 0.280
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.720 0.280
E72.2 Disorders of urea cycle metabolism
0.000 0.720 0.280
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.720 0.280
E72.0 Disorders of amino-acid transport
0.000 0.720 0.280
E75.6 Lipid storage disorder, unspecified
0.000 0.720 0.280
E75.5 Other lipid storage disorders
0.000 0.720 0.280
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.720 0.280
E75.3 Sphingolipidosis, unspecified
0.000 0.720 0.280
E75.2 Other sphingolipidosis
0.000 0.720 0.280
E75.1 Other gangliosidosis
0.000 0.720 0.280
E75.0 GM2 gangliosidosis
0.000 0.720 0.280
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.720 0.280
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.720 0.280
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.720 0.280
E76.2 Other mucopolysaccharidoses
0.000 0.720 0.280
E76.1 Mucopolysaccharidosis, type II
0.000 0.720 0.280
E76.0 Mucopolysaccharidosis, type I
0.000 0.720 0.280
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.720 0.280
E77.8 Other disorders of glycoprotein metabolism
0.000 0.720 0.280
E77.1 Defects in glycoprotein degradation
0.000 0.720 0.280
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.720 0.280
E84.9 Cystic fibrosis, unspecified
0.000 0.720 0.280
E84.8 Cystic fibrosis with other manifestations
0.000 0.720 0.280
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.720 0.280
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.720 0.280
E34.0 Carcinoid syndrome
0.000 0.722 0.278
E14 Unspecified diabetes mellitus
0.000 0.723 0.277
L40-L45 Papulosquamous disorders
0.000 0.726 0.273
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.727 0.273
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.727 0.273
E79.1 Lesch-Nyhan syndrome
0.000 0.727 0.273
E22 Hyperfunction of pituitary gland
0.000 0.727 0.273
E34.9 Endocrine disorder, unspecified
0.000 0.727 0.273
E65 Localised adiposity
0.000 0.727 0.272
L40.9 Psoriasis, unspecified
0.000 0.730 0.270
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.730 0.270
L43 Lichen planus
0.000 0.731 0.269
E67 Other hyperalimentation
0.000 0.732 0.268
E68 Sequelae of hyperalimentation
0.000 0.732 0.268
E46 Unspecified protein-energy malnutrition
0.000 0.733 0.267
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.733 0.267
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.733 0.267
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.733 0.267
E74.2 Disorders of galactose metabolism
0.000 0.733 0.267
E74.1 Disorders of fructose metabolism
0.000 0.733 0.267
E74.0 Glycogen storage disease
0.000 0.733 0.267
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.733 0.267
L43.9 Lichen planus, unspecified
0.000 0.735 0.265
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.736 0.264
L57.0 Actinic keratosis
0.000 0.737 0.263
E04 Other non-toxic goitre
0.000 0.749 0.251
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.751 0.249
E44.1 Mild protein-energy malnutrition
0.000 0.755 0.245
E44.0 Moderate protein-energy malnutrition
0.000 0.755 0.245
L72.1 Trichilemmal cyst
0.240 0.760 0.000
E20.9 Hypoparathyroidism, unspecified
0.001 0.769 0.230
E83 Disorders of mineral metabolism
0.056 0.774 0.170
L40.1 Generalised pustular psoriasis
0.000 0.777 0.223
E14.3 With ophthalmic complications
0.000 0.778 0.222
E27.5 Adrenomedullary hyperfunction
0.000 0.781 0.219
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.781 0.219
E27.0 Other adrenocortical overactivity
0.000 0.781 0.219
L43.8 Other lichen planus
0.000 0.785 0.214
E73.8 Other lactose intolerance
0.000 0.788 0.211
E73.1 Secondary lactase deficiency
0.000 0.788 0.211
E73.0 Congenital lactase deficiency
0.000 0.788 0.211
E14.1 With ketoacidosis
0.000 0.792 0.208
L40.4 Guttate psoriasis
0.000 0.792 0.208
L40.3 Pustulosis palmaris et plantaris
0.000 0.792 0.208
L40.2 Acrodermatitis continua
0.000 0.792 0.208
L42 Pityriasis rosea
0.000 0.792 0.207
E27.9 Disorder of adrenal gland, unspecified
0.000 0.793 0.207
E14.4 With neurological complications
0.000 0.795 0.205
E27.8 Other specified disorders of adrenal gland
0.000 0.796 0.203
E27.1 Primary adrenocortical insufficiency
0.000 0.797 0.203
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.800 0.200
E14.7 With multiple complications
0.000 0.801 0.199
E14.0 With coma
0.000 0.801 0.199
E14.5 With peripheral circulatory complications
0.000 0.803 0.197
L40.0 Psoriasis vulgaris
0.000 0.803 0.196
L44 Other papulosquamous disorders
0.000 0.804 0.196
L41 Parapsoriasis
0.000 0.804 0.196
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.804 0.196
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.804 0.196
E22.8 Other hyperfunction of pituitary gland
0.000 0.804 0.196
E89.2 Postprocedural hypoparathyroidism
0.000 0.804 0.196
E14.8 With unspecified complications
0.000 0.805 0.195
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.806 0.194
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.806 0.194
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.806 0.194
E89.5 Postprocedural testicular hypofunction
0.000 0.806 0.194
E89.3 Postprocedural hypopituitarism
0.000 0.806 0.194
L43.3 Subacute (active) lichen planus
0.000 0.807 0.193
L43.2 Lichenoid drug reaction
0.000 0.807 0.193
L43.1 Bullous lichen planus
0.000 0.807 0.193
L43.0 Hypertrophic lichen planus
0.000 0.807 0.193
E67.8 Other specified hyperalimentation
0.000 0.808 0.192
E67.3 Hypervitaminosis D
0.000 0.808 0.192
E67.2 Megavitamin-B6 syndrome
0.000 0.808 0.192
E67.1 Hypercarotenaemia
0.000 0.808 0.192
E67.0 Hypervitaminosis A
0.000 0.808 0.192
E14.2 Withrenal complications
0.000 0.810 0.190
E89.4 Postprocedural ovarian failure
0.000 0.816 0.183
E50-E64 Other nutritional deficiencies
0.001 0.819 0.181
E04.8 Other specified non-toxic goitre
0.000 0.820 0.180
E89.1 Postprocedural hypoinsulinaemia
0.000 0.828 0.172
E22.1 Hyperprolactinaemia
0.000 0.831 0.169
E14.6 With other specified complications
0.000 0.832 0.168
E83.9 Disorder of mineral metabolism, unspecified
0.040 0.838 0.122
E83.8 Other disorders of mineral metabolism
0.040 0.838 0.122
E83.2 Disorders of zinc metabolism
0.040 0.838 0.122
E83.0 Disorders of copper metabolism
0.040 0.838 0.122
E04.1 Non-toxic single thyroid nodule
0.000 0.840 0.160
E04.0 Non-toxic diffuse goitre
0.000 0.842 0.158
L57 Skin changes due to chronic exposure to nonionising radiation
0.001 0.845 0.155
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.847 0.153
E83.3 Disorders of phosphorus metabolism
0.026 0.856 0.118
L41.9 Parapsoriasis, unspecified
0.000 0.859 0.141
L41.8 Other parapsoriasis
0.000 0.859 0.141
L41.5 Retiform parapsoriasis
0.000 0.859 0.141
L41.4 Large plaque parapsoriasis
0.000 0.859 0.141
L41.3 Small plaque parapsoriasis
0.000 0.859 0.141
L41.2 Lymphomatoid papulosis
0.000 0.859 0.141
L41.1 Pityriasis lichenoides chronica
0.000 0.859 0.141
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.859 0.141
L44.9 Papulosquamous disorder, unspecified
0.000 0.859 0.141
L44.8 Other specified papulosquamous disorders
0.000 0.859 0.141
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.859 0.141
L44.3 Lichen ruber moniliformis
0.000 0.859 0.141
L44.2 Lichen striatus
0.000 0.859 0.141
L44.1 Lichen nitidus
0.000 0.859 0.141
L44.0 Pityriasis rubra pilaris
0.000 0.859 0.141
L40.8 Other psoriasis
0.000 0.859 0.140
K90 Intestinal malabsorption
0.000 0.861 0.138
E27.2 Addisonian crisis
0.001 0.865 0.134
E04.9 Non-toxic goitre, unspecified
0.000 0.868 0.132
E89.0 Postprocedural hypothyroidism
0.000 0.868 0.132
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.870 0.130
E56 Other vitamin deficiencies
0.001 0.870 0.130
E51 Thiamine deficiency
0.001 0.870 0.130
E50 Vitamin A deficiency
0.001 0.870 0.130
E60 Dietary zinc deficiency
0.001 0.870 0.130
E59 Dietary selenium deficiency
0.001 0.870 0.130
E54 Ascorbic acid deficiency
0.001 0.870 0.130
E52 Niacin deficiency [pellagra]
0.001 0.870 0.130
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.001 0.870 0.129
E58 Dietary calcium deficiency
0.001 0.873 0.127
E83.4 Disorders of magnesium metabolism
0.016 0.873 0.111
E63 Other nutritional deficiencies
0.001 0.880 0.119
E11.4 With neurological complications
0.000 0.882 0.118
E73.9 Lactose intolerance, unspecified
0.001 0.884 0.115
E07.9 Disorder of thyroid, unspecified
0.000 0.886 0.114
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.887 0.112
L57.5 Actinic granuloma
0.001 0.889 0.111
L57.3 Poikiloderma of Civatte
0.001 0.889 0.111
L57.2 Cutis rhomboidalis nuchae
0.001 0.889 0.111
L57.1 Actinic reticuloid
0.001 0.889 0.111
L56 Other acute skin changes due to ultraviolet radiation
0.001 0.889 0.111
E22.0 Acromegaly and pituitary gigantism
0.001 0.893 0.106
E61 Deficiency of other nutrient elements
0.000 0.893 0.106
K90.3 Pancreatic steatorrhoea
0.000 0.900 0.099
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.900 0.099
K90.1 Tropical sprue
0.000 0.900 0.099
E04.2 Non-toxic multinodular goitre
0.000 0.903 0.097
Chapter XII Diseases of the skin and subcutaneous tissue
0.002 0.905 0.093
E50.9 Vitamin A deficiency, unspecified
0.001 0.906 0.093
E50.8 Other manifestations of vitamin A deficiency
0.001 0.906 0.093
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.906 0.093
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.906 0.093
E50.5 Vitamin A deficiency with night blindness
0.001 0.906 0.093
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.906 0.093
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.906 0.093
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.906 0.093
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.906 0.093
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.906 0.093
E51.9 Thiamine deficiency, unspecified
0.001 0.906 0.093
E51.8 Other manifestations of thiamine deficiency
0.001 0.906 0.093
E51.2 Wernicke's encephalopathy
0.001 0.906 0.093
E51.1 Beriberi
0.001 0.906 0.093
E56.9 Vitamin deficiency, unspecified
0.001 0.906 0.093
E56.8 Deficiency of other vitamins
0.001 0.906 0.093
E56.1 Deficiency of vitamin K
0.001 0.906 0.093
E56.0 Deficiency of vitamin E
0.001 0.906 0.093
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.906 0.093
E64.8 Sequelae of other nutritional deficiencies
0.001 0.906 0.093
E64.3 Sequelae of rickets
0.001 0.906 0.093
E64.2 Sequelae of vitamin C deficiency
0.001 0.906 0.093
E64.1 Sequelae of vitamin A deficiency
0.001 0.906 0.093
E64.0 Sequelae of protein-energy malnutrition
0.001 0.906 0.093
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.001 0.907 0.093
L58 Radiodermatitis
0.001 0.907 0.093
L55 Sunburn
0.001 0.907 0.093
L57.4 Cutis laxa senilis
0.001 0.907 0.093
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.908 0.091
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.910 0.089
E63.8 Other specified nutritional deficiencies
0.001 0.914 0.086
E63.1 Imbalance of constituents of food intake
0.001 0.914 0.086
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.914 0.086
K90.8 Other intestinal malabsorption
0.000 0.914 0.086
E55 Vitamin D deficiency
0.001 0.917 0.083
L56.4 Polymorphous light eruption
0.001 0.920 0.079
L56.3 Solar urticaria
0.001 0.920 0.079
L56.2 Photocontact dermatitis [berloque dermatitis]
0.001 0.920 0.079
L56.1 Drug photoallergic response
0.001 0.920 0.079
L56.0 Drug phototoxic response
0.001 0.920 0.079
E86 Volume depletion
0.000 0.920 0.080
E66 Obesity
0.000 0.923 0.077
E61.9 Deficiency of nutrient element, unspecified
0.000 0.923 0.076
E61.8 Deficiency of other specified nutrient elements
0.000 0.923 0.076
E61.7 Deficiency of multiple nutrient elements
0.000 0.923 0.076
E61.6 Vanadium deficiency
0.000 0.923 0.076
E61.5 Molybdenum deficiency
0.000 0.923 0.076
E61.4 Chromium deficiency
0.000 0.923 0.076
E61.3 Manganese deficiency
0.000 0.923 0.076
E61.0 Copper deficiency
0.000 0.923 0.076
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.924 0.076
E63.9 Nutritional deficiency, unspecified
0.001 0.924 0.075
E61.2 Magnesium deficiency
0.000 0.928 0.071
L10-L14 Bullous disorders
0.002 0.932 0.067
L55.9 Sunburn, unspecified
0.001 0.933 0.067
L55.8 Other sunburn
0.001 0.933 0.067
L55.2 Sunburn of third degree
0.001 0.933 0.067
L55.1 Sunburn of second degree
0.001 0.933 0.067
L55.0 Sunburn of first degree
0.001 0.933 0.067
L58.9 Radiodermatitis, unspecified
0.001 0.933 0.067
L58.1 Chronic radiodermatitis
0.001 0.933 0.067
L58.0 Acute radiodermatitis
0.001 0.933 0.067
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.001 0.933 0.067
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.001 0.933 0.067
L59.0 Erythema ab igne [dermatitis ab igne]
0.001 0.933 0.067
E53 Deficiency of other B group vitamins
0.001 0.937 0.062
E61.1 Iron deficiency
0.000 0.939 0.060
E55.0 Rickets, active
0.001 0.940 0.059
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.940 0.060
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.001 0.941 0.059
E66.1 Drug-induced obesity
0.000 0.944 0.056
L12 Pemphigoid
0.001 0.946 0.053
E66.0 Obesity due to excess calories
0.000 0.948 0.052
K90.9 Intestinal malabsorption, unspecified
0.000 0.948 0.052
E83.5 Disorders of calcium metabolism
0.014 0.949 0.038
L10 Pemphigus
0.001 0.951 0.048

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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