TreeWAS – Variant ID: rs10452033

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M35.3 Polymyalgia rheumatica	0.076	0.924	0.000
M35 Other systemic involvement of connective tissue	0.035	0.965	0.000
M35.7 Hypermobility syndrome	0.027	0.973	0.000
M35.8 Other specified systemic involvement of connective tissue	0.026	0.974	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.025	0.975	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.025	0.975	0.000
M35.5 Multifocal fibrosclerosis	0.025	0.975	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.025	0.975	0.000
M35.2 Behcet's disease	0.025	0.975	0.000
M35.0 Sicca syndrome [Sjogren]	0.025	0.975	0.000
M35.1 Other overlap syndromes	0.023	0.977	0.000
J92.0 Pleural plaque with presence of asbestos	0.022	0.978	0.000
J92.9 Pleural plaque without asbestos	0.021	0.979	0.000
Z57.2 Occupational exposure to dust	0.020	0.980	0.000
J92 Pleural plaque	0.020	0.980	0.000
Z57 Occupational exposure to risk-factors	0.019	0.981	0.000
Z57.3 Occupational exposure to other air contaminants	0.019	0.981	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.018	0.982	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.017	0.983	0.000
Z57.8 Occupational exposure to other risk-factors	0.016	0.984	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.014	0.986	0.000
Z57.7 Occupational exposure to vibration	0.014	0.986	0.000
Z57.6 Occupational exposure to extreme temperature	0.014	0.986	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.014	0.986	0.000
Z57.1 Occupational exposure to radiation	0.014	0.986	0.000
Z57.0 Occupational exposure to noise	0.014	0.986	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.989	0.011
K13 Other diseases of lip and oral mucosa	0.000	0.992	0.008
K13.0 Diseases of lips	0.000	0.993	0.007
M79.69 Pain in limb (Site unspecified)	0.007	0.993	0.000
H43.1 Vitreous haemorrhage	0.000	0.993	0.007
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.994	0.006
H43.3 Other vitreous opacities	0.000	0.994	0.006
H43 Disorders of vitreous body	0.000	0.994	0.006
Z89.6 Acquired absence of leg above knee	0.006	0.994	0.000
N43.3 Hydrocele, unspecified	0.006	0.994	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.000	0.994	0.006
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.000	0.994	0.006
K13.5 Oral submucous fibrosis	0.000	0.994	0.006
K13.3 Hairy leukoplakia	0.000	0.994	0.006
K13.1 Cheek and lip biting	0.000	0.994	0.006
R87.6 Abnormal cytological findings	0.000	0.994	0.006
H43.8 Other disorders of vitreous body	0.000	0.994	0.006
K29.4 Chronic atrophic gastritis	0.006	0.994	0.000
H44.2 Degenerative myopia	0.000	0.995	0.005
Z99.8 Dependence on other enabling machines and devices	0.005	0.995	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.005	0.995	0.000
H44 Disorders of globe	0.000	0.995	0.005
H43.2 Crystalline deposits in vitreous body	0.000	0.995	0.004
M07.39 Other psoriatic arthropathies (Site unspecified)	0.005	0.995	0.000
Z99.1 Dependence on respirator	0.005	0.995	0.000
Z89 Acquired absence of limb	0.004	0.996	0.000
H43-H45 Disorders of vitreous body and globe	0.000	0.996	0.004
K13.29 Other disturbances of oral epithelium, including tongue	0.000	0.996	0.004
M07.3 Other psoriatic arthropathies	0.004	0.996	0.000
S62.50 Fracture of thumb (closed)	0.004	0.996	0.000
H43.0 Vitreous prolapse	0.000	0.996	0.004
H44.4 Hypotony of eye	0.000	0.996	0.004
Z89.4 Acquired absence of foot and ankle	0.004	0.996	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.004	0.996	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.004	0.996	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.996	0.004
S19.9 Unspecified injury of neck	0.004	0.996	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.004	0.996	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.004	0.996	0.000
Z89.5 Acquired absence of leg at or below knee	0.004	0.996	0.000
H44.8 Other disorders of globe	0.000	0.996	0.003
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.000	0.996	0.003
H44.6 Retained (old) intraocular foreign body, magnetic	0.000	0.996	0.003
H44.5 Degenerated conditions of globe	0.000	0.996	0.003
H44.3 Other degenerative disorders of globe	0.000	0.996	0.003
H44.1 Other endophthalmitis	0.000	0.996	0.003
S62.5 Fracture of thumb	0.003	0.996	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.003	0.996	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.003	0.996	0.000
Z89.9 Acquired absence of limb, unspecified	0.003	0.996	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.003	0.997	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.003	0.997	0.000
Z89.1 Acquired absence of hand and wrist	0.003	0.997	0.000
Z89.2 Acquired absence of upper limb above wrist	0.003	0.997	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.997	0.003
M07.38 Other psoriatic arthropathies (Other)	0.003	0.997	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.003	0.997	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.003	0.997	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.003	0.997	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.003	0.997	0.000
I07.1 Tricuspid insufficiency	0.003	0.997	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.003	0.997	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.003	0.997	0.000
S62.2 Fracture of first metacarpal bone	0.003	0.997	0.000
E55.9 Vitamin D deficiency, unspecified	0.003	0.997	0.000
H44.9 Disorder of globe, unspecified	0.000	0.997	0.003
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.000	0.997	0.003
Z99.9 Dependence on unspecified enabling machine and device	0.003	0.997	0.000
Z99.4 Dependence on artificial heart	0.003	0.997	0.000
Z99.0 Dependence on aspirator	0.003	0.997	0.000
Z99.3 Dependence on wheelchair	0.003	0.997	0.000
Z99.2 Dependence on renal dialysis	0.003	0.997	0.000
J94 Other pleural conditions	0.003	0.997	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.003	0.997	0.000
J94.1 Fibrothorax	0.003	0.997	0.000
S62 Fracture at wrist and hand level	0.003	0.997	0.000
R54 Senility	0.000	0.997	0.003
S62.0 Fracture of navicular [scaphoid] bone of hand	0.003	0.997	0.000
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
S62.51 Fracture of thumb (open)	0.003	0.997	0.000
S19.8 Other specified injuries of neck	0.003	0.997	0.000
Z91.6 Personal history of other physical trauma	0.003	0.997	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.000	0.997	0.003
H45.1 Endophthalmitis in diseases classified elsewhere	0.000	0.997	0.003
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.000	0.997	0.003
J94.8 Other specified pleural conditions	0.003	0.997	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.003	0.997	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.003	0.997	0.000
J90-J94 Other diseases of pleura	0.003	0.997	0.000
R87 Abnormal findings in specimens from female genital organs	0.000	0.997	0.003
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.003	0.997	0.000
J94.2 Haemothorax	0.002	0.997	0.000
L73.2 Hidradenitis suppurativa	0.000	0.997	0.003
S62.21 Fracture of first metacarpal bone (open)	0.002	0.997	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.997	0.003
S19.7 Multiple injuries of neck	0.002	0.997	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
J94.9 Pleural condition, unspecified	0.002	0.998	0.000
J94.0 Chylous effusion	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.002	0.998	0.000
N43 Hydrocele and spermatocele	0.002	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.998	0.000
S62.7 Multiple fractures of fingers	0.002	0.998	0.000
S62.1 Fracture of other carpal bone(s)	0.002	0.998	0.000
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
R87.8 Other abnormal findings	0.000	0.998	0.002
R87.5 Abnormal microbiological findings	0.000	0.998	0.002
R87.4 Abnormal immunological findings	0.000	0.998	0.002
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.998	0.002
R87.1 Abnormal level of hormones	0.000	0.998	0.002
R87.0 Abnormal level of enzymes	0.000	0.998	0.002
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.998	0.002
K70.4 Alcoholic hepatic failure	0.002	0.998	0.000
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
S62.31 Fracture of other metacarpal bone (open)	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
I77.1 Stricture of artery	0.000	0.998	0.002
S11.9 Open wound of neck, part unspecified	0.002	0.998	0.000
S13.5 Sprain and strain of thyroid region	0.002	0.998	0.000
S13.3 Multiple dislocations of neck	0.002	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.002	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.002	0.998	0.000
C77.8 Lymph nodes of multiple regions	0.002	0.998	0.000
N41.1 Chronic prostatitis	0.000	0.998	0.002
R87.9 Unspecified abnormal finding	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
R87.7 Abnormal histological findings	0.000	0.998	0.002
S62.41 Multiple fractures of metacarpal bones (open)	0.002	0.998	0.000
N43.2 Other hydrocele	0.002	0.998	0.000
N43.1 Infected hydrocele	0.002	0.998	0.000
N43.0 Encysted hydrocele	0.002	0.998	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
K55 Vascular disorders of intestine	0.000	0.998	0.002
K43.9 Ventral hernia without obstruction or gangrene	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.000	0.998	0.002
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.998	0.002
M07.6 Other enteropathic arthropathies	0.002	0.998	0.000
K70 Alcoholic liver disease	0.002	0.998	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.002	0.998	0.000
L40.0 Psoriasis vulgaris	0.000	0.998	0.002
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
Z50.0 Cardiac rehabilitation	0.000	0.998	0.002
N43.4 Spermatocele	0.002	0.998	0.000
S17 Crushing injury of neck	0.002	0.998	0.000
S15 Injury of blood vessels at neck level	0.002	0.998	0.000
S18 Traumatic amputation at neck level	0.002	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.002	0.998	0.000
D37.5 Rectum	0.000	0.998	0.002
K09.2 Other cysts of jaw	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
M07.5 Arthropathy in ulcerative colitis	0.002	0.998	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.002	0.998	0.000
M07.2 Psoriatic spondylitis	0.002	0.998	0.000
M07.1 Arthritis mutilans	0.002	0.998	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.002	0.998	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
S14.3 Injury of brachial plexus	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.002	0.998	0.000
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
S11.8 Open wound of other parts of neck	0.002	0.998	0.000
S11.7 Multiple open wounds of neck	0.002	0.998	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.002	0.998	0.000
S11.1 Open wound involving thyroid gland	0.002	0.998	0.000
S11.0 Open wound involving larynx and trachea	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.998	0.002
S10 Superficial injury of neck	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
K70.0 Alcoholic fatty liver	0.002	0.998	0.000
L52 Erythema nodosum	0.000	0.998	0.002
M07.69 Other enteropathic arthropathies (Site unspecified)	0.002	0.998	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.001	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
F41.1 Generalised anxiety disorder	0.002	0.998	0.000
F43.2 Adjustment disorders	0.000	0.998	0.002
L29.0 Pruritus ani	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
S27.1 Traumatic haemothorax	0.002	0.998	0.000
D69.0 Allergic purpura	0.002	0.998	0.000
Z48.0 Attention to surgical dressings and sutures	0.000	0.998	0.002
M07.68 Other enteropathic arthropathies (Other)	0.001	0.998	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.001	0.998	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.001	0.998	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.001	0.998	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.001	0.998	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.001	0.998	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.001	0.998	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.001	0.998	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.001	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.001	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
H18 Other disorders of cornea	0.000	0.998	0.002
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.998	0.002
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.998	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.000	0.998	0.002
N60.9 Benign mammary dysplasia, unspecified	0.002	0.998	0.000
S62.6 Fracture of other finger	0.002	0.998	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.998	0.000
E10.1 With ketoacidosis	0.000	0.998	0.002
K55.8 Other vascular disorders of intestine	0.000	0.998	0.002
L73.9 Follicular disorder, unspecified	0.000	0.998	0.002
S14.6 Injury of other and unspecified nerves of neck	0.001	0.998	0.000
S14.5 Injury of cervical sympathetic nerves	0.001	0.998	0.000
S14.4 Injury of peripheral nerves of neck	0.001	0.998	0.000
S14.2 Injury of nerve root of cervical spine	0.001	0.998	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.001	0.998	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.001	0.998	0.000
S15.8 Injury of other blood vessels at neck level	0.001	0.998	0.000
S15.7 Injury of multiple blood vessels at neck level	0.001	0.998	0.000
S15.3 Injury of internal jugular vein	0.001	0.998	0.000
S15.2 Injury of external jugular vein	0.001	0.998	0.000
S15.1 Injury of vertebral artery	0.001	0.998	0.000
S15.0 Injury of carotid artery	0.001	0.998	0.000
S17.9 Crushing injury of neck, part unspecified	0.001	0.998	0.000
S17.8 Crushing injury of other parts of neck	0.001	0.998	0.000
S17.0 Crushing injury of larynx and traches	0.001	0.998	0.000
E55 Vitamin D deficiency	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.998	0.000
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
S12 Fracture of neck	0.001	0.998	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.001	0.998	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.001	0.998	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.001	0.998	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.001	0.998	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.001	0.998	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.001	0.998	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.001	0.998	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.001	0.998	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.001	0.998	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.001	0.998	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.001	0.998	0.000
M07.18 Arthritis mutilans (Other)	0.001	0.998	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.001	0.998	0.000
M07.16 Arthritis mutilans (Lower leg)	0.001	0.998	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.001	0.998	0.000
M07.14 Arthritis mutilans (Hand)	0.001	0.998	0.000
M07.13 Arthritis mutilans (Forearm)	0.001	0.998	0.000
M07.12 Arthritis mutilans (Upper arm)	0.001	0.998	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.001	0.998	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.001	0.998	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.001	0.998	0.000
M07.28 Psoriatic spondylitis (Other)	0.001	0.998	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.001	0.998	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.001	0.998	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.001	0.998	0.000
M07.24 Psoriatic spondylitis (Hand)	0.001	0.998	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.001	0.998	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.001	0.998	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.001	0.998	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.001	0.998	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.001	0.998	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.001	0.998	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.001	0.998	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.001	0.998	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.001	0.998	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.001	0.998	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.001	0.998	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.001	0.998	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.001	0.998	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.001	0.998	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.001	0.998	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.001	0.998	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.001	0.998	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.001	0.998	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.001	0.998	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.001	0.998	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.001	0.998	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.001	0.998	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.001	0.998	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.001	0.998	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.001	0.998	0.000
H91.9 Hearing loss, unspecified	0.000	0.998	0.002
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
S10.8 Superficial injury of other parts of neck	0.001	0.998	0.000
S10.7 Multiple superficial injuries of neck	0.001	0.998	0.000
S10.1 Other and unspecified superficial injuries of throat	0.001	0.998	0.000
S10.0 Contusion of throat	0.001	0.998	0.000
Z01.4 Gynaecological examination (general)(routine)	0.000	0.998	0.002
L73 Other follicular disorders	0.000	0.998	0.002
K57.2 Diverticular disease of large intestine with perforation and abscess	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
K70.1 Alcoholic hepatitis	0.001	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.001
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.001	0.998	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.001	0.999	0.000
I97.1 Other functional disturbances following cardiac surgery	0.001	0.999	0.000
L50.9 Urticaria, unspecified	0.000	0.999	0.001
M77.9 Enthesopathy, unspecified	0.001	0.999	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999	0.000
M77.02 Medial epicondylitis (Upper arm)	0.001	0.999	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
R30.0 Dysuria	0.000	0.999	0.001
H18.7 Other corneal deformities	0.000	0.999	0.001
H18.3 Changes in corneal membranes	0.000	0.999	0.001
S10.9 Superficial injury of neck, part unspecified	0.001	0.999	0.000
W19.3 Sports and athletics area	0.000	0.999	0.001
M89.03 Algoneurodystrophy (Forearm)	0.001	0.999	0.000
D69.4 Other primary thrombocytopenia	0.001	0.999	0.000
E55.0 Rickets, active	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.000	0.999	0.001
L50.1 Idiopathic urticaria	0.000	0.999	0.001
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.001	0.999	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.001	0.999	0.000
A49.0 Staphylococcal infection, unspecified	0.001	0.999	0.000
D69.8 Other specified haemorrhagic conditions	0.001	0.999	0.000
D69.1 Qualitative platelet defects	0.001	0.999	0.000
I07.9 Tricuspid valve disease, unspecified	0.001	0.999	0.000
I07.8 Other tricuspid valve diseases	0.001	0.999	0.000
I07.2 Tricuspid stenosis with insufficiency	0.001	0.999	0.000
I07.0 Tricuspid stenosis	0.001	0.999	0.000
M89.0 Algoneurodystrophy	0.001	0.999	0.000
S12.8 Fracture of other parts of neck	0.001	0.999	0.000
S12.0 Fracture of first cervical vertebra	0.001	0.999	0.000
D67 Hereditary factor IX deficiency	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
H18.1 Bullous keratopathy	0.000	0.999	0.001
L73.1 Pseudofolliculitis barbae	0.000	0.999	0.001
L73.0 Acne keloid	0.000	0.999	0.001
M54.4 Lumbago with sciatica	0.001	0.999	0.000
S12.1 Fracture of second cervical vertebra	0.001	0.999	0.000
S27.9 Injury of unspecified intrathoracic organ	0.001	0.999	0.000
S27.7 Multiple injuries of intrathoracic organs	0.001	0.999	0.000
S27.6 Injury of pleura	0.001	0.999	0.000
S27.5 Injury of thoracic trachea	0.001	0.999	0.000
S27.4 Injury of bronchus	0.001	0.999	0.000
Z49.0 Preparatory care for dialysis	0.001	0.999	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.999	0.001
M77.94 Enthesopathy, unspecified (Hand)	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.001	0.999	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.001	0.999	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.001	0.999	0.000
L73.8 Other specified follicular disorders	0.000	0.999	0.001
R84.5 Abnormal microbiological findings	0.000	0.999	0.001
L50 Urticaria	0.000	0.999	0.001
M77.99 Enthesopathy, unspecified (Site unspecified)	0.001	0.999	0.000
M77.98 Enthesopathy, unspecified (Other)	0.001	0.999	0.000
M77.93 Enthesopathy, unspecified (Forearm)	0.001	0.999	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.001	0.999	0.000
M77.90 Enthesopathy, unspecified (Multiple sites)	0.001	0.999	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.001	0.999	0.000
D69.5 Secondary thrombocytopenia	0.001	0.999	0.000
D69.2 Other nonthrombocytopenic purpura	0.001	0.999	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.999	0.000
H18.4 Corneal degeneration	0.000	0.999	0.001
K63.1 Perforation of intestine (nontraumatic)	0.001	0.999	0.000
Q66.3 Other congenital varus deformities of feet	0.001	0.999	0.000
S27.8 Injury of other specified intrathoracic organs	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.999	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.999	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.999	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.999	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.001	0.999	0.000
K55.9 Vascular disorder of intestine, unspecified	0.000	0.999	0.001
S27.2 Traumatic heamopneumothorax	0.001	0.999	0.000
W06.0 Home	0.000	0.999	0.001
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.999	0.001
C18.0 Caecum	0.001	0.999	0.000
H18.2 Other corneal oedema	0.000	0.999	0.001
I84.5 External haemorrhoids without complication	0.000	0.999	0.001
L51.1 Bullous erythema multiforme	0.000	0.999	0.001
S12.9 Fracture of neck, part unspecified	0.001	0.999	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.001	0.999	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.001	0.999	0.000
D56.1 Beta thalassaemia	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.999	0.000
S27.3 Other injuries of lung	0.001	0.999	0.000
D66 Hereditary factor VIII deficiency	0.001	0.999	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.001	0.999	0.000
M54.44 Lumbago with sciatica-Thoracic	0.001	0.999	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.001	0.999	0.000
M54.42 Lumbago with sciatica-Cervical	0.001	0.999	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.001	0.999	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.001	0.999	0.000
M89.08 Algoneurodystrophy (Other)	0.001	0.999	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.999	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.999	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.001	0.999	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.999	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.001	0.999	0.000
S12.01 Fracture of first cervical vertebra (open)	0.001	0.999	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.001	0.999	0.000
S12.81 Fracture of other parts of neck (open)	0.001	0.999	0.000
S12.80 Fracture of other parts of neck (closed)	0.001	0.999	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.001	0.999	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.001	0.999	0.000
F52.2 Failure of genital response	0.000	0.999	0.001
S12.2 Fracture of other specified cervical vertebra	0.001	0.999	0.000
S12.11 Fracture of second cervical vertebra (open)	0.001	0.999	0.000
F45.3 Somatoform autonomic dysfunction	0.001	0.999	0.000
Q83.8 Other congenital malformations of breast	0.001	0.999	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.001	0.999	0.000
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
L50.8 Other urticaria	0.000	0.999	0.001
L50.6 Contact urticaria	0.000	0.999	0.001
L50.5 Cholinergic urticaria	0.000	0.999	0.001
L50.4 Vibratory urticaria	0.000	0.999	0.001
L50.3 Dermatographic urticaria	0.000	0.999	0.001
L50.2 Urticaria due to cold and heat	0.000	0.999	0.001
M89 Other disorders of bone	0.001	0.999	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.999	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.999	0.001
J35.1 Hypertrophy of tonsils	0.000	0.999	0.001
D86 Sarcoidosis	0.001	0.999	0.000
R30 Pain associated with micturition	0.000	0.999	0.001
S12.91 Fracture of neck, part unspecified (open)	0.001	0.999	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.001	0.999	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.999	0.000
E80.4 Gilbert's syndrome	0.001	0.999	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.001	0.999	0.000
N64.5 Other signs and symptoms in breast	0.001	0.999	0.000
J91 Pleural effusion in conditions classified elsewhere	0.001	0.999	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.001	0.999	0.000
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.999	0.001
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.999	0.001
W27.6 Industrial and construction area	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
H18.6 Keratoconus	0.000	0.999	0.001
J93.0 Spontaneous tension pneumothorax	0.001	0.999	0.000
M89.6 Osteopathy after poliomyelitis	0.001	0.999	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.001	0.999	0.000
M89.2 Other disorders of bone development and growth	0.001	0.999	0.000
M89.1 Epiphyseal arrest	0.001	0.999	0.000
R30.1 Vesical tenesmus	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations