TreeWAS – Variant ID: rs1047964

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E66.9 Obesity, unspecified	0.000	0.993	0.007
E66 Obesity	0.000	0.993	0.007
E66.8 Other obesity	0.000	0.994	0.006
E03.9 Hypothyroidism, unspecified	0.000	0.995	0.005
E65-E68 Obesity and other hyperalimentation	0.000	0.995	0.005
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.995	0.005
E66.1 Drug-induced obesity	0.000	0.995	0.005
E66.0 Obesity due to excess calories	0.000	0.995	0.005
E03 Other hypothyroidism	0.000	0.995	0.005
R55 Syncope and collapse	0.005	0.995	0.000
E00-E07 Disorders of thyroid gland	0.000	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.995	0.005
E70-E90 Metabolic disorders	0.000	0.996	0.004
E86 Volume depletion	0.000	0.996	0.004
E20-E35 Disorders of other endocrine glands	0.000	0.996	0.004
E67 Other hyperalimentation	0.000	0.996	0.004
E68 Sequelae of hyperalimentation	0.000	0.996	0.004
E65 Localised adiposity	0.000	0.996	0.004
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.996	0.004
E83 Disorders of mineral metabolism	0.000	0.996	0.004
E07 Other disorders of thyroid	0.000	0.996	0.004
E03.8 Other specified hypothyroidism	0.000	0.996	0.004
E03.5 Myxoedema coma	0.000	0.996	0.004
E03.4 Atrophy of thyroid (acquired)	0.000	0.996	0.004
E03.3 Postinfectious hypothyroidism	0.000	0.996	0.004
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.996	0.004
E03.1 Congenital hypothyroidism without goitre	0.000	0.996	0.004
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.996	0.004
E89.0 Postprocedural hypothyroidism	0.000	0.996	0.004
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.996	0.004
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.996	0.004
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.996	0.003
E00 Congenital iodine-deficiency syndrome	0.000	0.996	0.003
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.996	0.003
E04 Other non-toxic goitre	0.000	0.996	0.004
E83.5 Disorders of calcium metabolism	0.000	0.996	0.004
E40-E46 Malnutrition	0.000	0.996	0.003
E88 Other metabolic disorders	0.000	0.997	0.003
E06 Thyroiditis	0.000	0.997	0.003
E85 Amyloidosis	0.000	0.997	0.003
E84 Cystic fibrosis	0.000	0.997	0.003
E79 Disorders of purine and pyrimidine metabolism	0.000	0.997	0.003
E77 Disorders of glycoprotein metabolism	0.000	0.997	0.003
E76 Disorders of glycosaminoglycan metabolism	0.000	0.997	0.003
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.997	0.003
E74 Other disorders of carbohydrate metabolism	0.000	0.997	0.003
E73 Lactose intolerance	0.000	0.997	0.003
E72 Other disorders of amino-acid metabolism	0.000	0.997	0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.997	0.003
E70 Disorders of aromatic amino-acid metabolism	0.000	0.997	0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.997	0.003
E21.0 Primary hyperparathyroidism	0.000	0.997	0.003
E23 Hypofunction and other disorders of pituitary gland	0.000	0.997	0.003
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.997	0.003
R94.5 Abnormal results of liver function studies	0.000	0.997	0.003
E28 Ovarian dysfunction	0.000	0.997	0.003
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.997	0.003
E83.4 Disorders of magnesium metabolism	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E34 Other endocrine disorders	0.000	0.997	0.003
E32 Diseases of thymus	0.000	0.997	0.003
E31 Polyglandular dysfunction	0.000	0.997	0.003
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.003
E29 Testicular dysfunction	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.000	0.997	0.003
E26 Hyperaldosteronism	0.000	0.997	0.003
E25 Adrenogenital disorders	0.000	0.997	0.003
E24 Cushing's syndrome	0.000	0.997	0.003
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
E20 Hypoparathyroidism	0.000	0.997	0.003
E67.8 Other specified hyperalimentation	0.000	0.997	0.003
E67.3 Hypervitaminosis D	0.000	0.997	0.003
E67.2 Megavitamin-B6 syndrome	0.000	0.997	0.003
E67.1 Hypercarotenaemia	0.000	0.997	0.003
E67.0 Hypervitaminosis A	0.000	0.997	0.003
E50-E64 Other nutritional deficiencies	0.000	0.997	0.003
E07.9 Disorder of thyroid, unspecified	0.000	0.997	0.003
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.997	0.003
E83.3 Disorders of phosphorus metabolism	0.000	0.997	0.003
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.997	0.003
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.997	0.003
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.997	0.003
E89.5 Postprocedural testicular hypofunction	0.000	0.997	0.003
E89.4 Postprocedural ovarian failure	0.000	0.997	0.003
E89.3 Postprocedural hypopituitarism	0.000	0.997	0.003
E89.2 Postprocedural hypoparathyroidism	0.000	0.997	0.003
E89.1 Postprocedural hypoinsulinaemia	0.000	0.997	0.003
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.997	0.003
E83.8 Other disorders of mineral metabolism	0.000	0.997	0.003
E83.2 Disorders of zinc metabolism	0.000	0.997	0.003
E83.0 Disorders of copper metabolism	0.000	0.997	0.003
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
Z03.8 Observation for other suspected diseases and conditions	0.000	0.997	0.003
E07.8 Other specified disorders of thyroid	0.000	0.997	0.003
E07.1 Dyshormogenetic goitre	0.000	0.997	0.003
E07.0 Hypersecretion of calcitonin	0.000	0.997	0.003
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.997	0.003
E21.4 Other specified disorders of parathyroid gland	0.000	0.997	0.003
E21.2 Other hyperparathyroidism	0.000	0.997	0.003
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.997	0.003
E05.9 Thyrotoxicosis, unspecified	0.000	0.997	0.003
E04.9 Non-toxic goitre, unspecified	0.000	0.997	0.003
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
E05.8 Other thyrotoxicosis	0.000	0.997	0.003
E05.5 Thyroid crisis or storm	0.000	0.997	0.003
E05.4 Thyrotoxicosis factitia	0.000	0.997	0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.997	0.003
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.997	0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.997	0.003
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.997	0.003
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.997	0.003
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.997	0.003
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.997	0.003
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.003
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.997	0.003
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.997	0.003
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.997	0.003
E23.0 Hypopituitarism	0.000	0.997	0.003
E04.8 Other specified non-toxic goitre	0.000	0.997	0.003
E04.0 Non-toxic diffuse goitre	0.000	0.997	0.003
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.997	0.003
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.997	0.003
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.997	0.003
E46 Unspecified protein-energy malnutrition	0.000	0.997	0.003
E45 Retarded development following protein-energy malnutrition	0.000	0.997	0.003
E43 Unspecified severe protein-energy malnutrition	0.000	0.997	0.003
E42 Marasmic kwashiorkor	0.000	0.997	0.003
E41 Nutritional marasmus	0.000	0.997	0.003
E40 Kwashiorkor	0.000	0.997	0.003
E87.6 Hypokalaemia	0.000	0.997	0.003
E28.2 Polycystic ovarian syndrome	0.000	0.997	0.003
E88.9 Metabolic disorder, unspecified	0.000	0.997	0.003
E88.8 Other specified metabolic disorders	0.000	0.997	0.003
E88.3 Tumour lysis syndrome	0.000	0.997	0.003
E88.2 Lipomatosis, not elsewhere classified	0.000	0.997	0.003
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.997	0.003
E06.9 Thyroiditis, unspecified	0.000	0.997	0.002
E06.5 Other chronic thyroiditis	0.000	0.997	0.002
E06.4 Drug-induced thyroiditis	0.000	0.997	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.997	0.002
E06.1 Subacute thyroiditis	0.000	0.997	0.002
E06.0 Acute thyroiditis	0.000	0.997	0.002
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.000	0.997	0.003
E23.1 Drug-induced hypopituitarism	0.000	0.997	0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.997	0.003
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.997	0.003
E70.3 Albinism	0.000	0.997	0.003
E70.2 Disorders of tyrosine metabolism	0.000	0.997	0.003
E70.1 Other hyperphenylalaninaemias	0.000	0.997	0.003
E70.0 Classical phenylketonuria	0.000	0.997	0.003
E71.3 Disorders of fatty-acid metabolism	0.000	0.997	0.003
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.997	0.003
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.997	0.003
E71.0 Maple-syrup-urine disease	0.000	0.997	0.003
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.997	0.003
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.997	0.003
E72.5 Disorders of glycine metabolism	0.000	0.997	0.003
E72.4 Disorders of ornithine metabolism	0.000	0.997	0.003
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.997	0.003
E72.2 Disorders of urea cycle metabolism	0.000	0.997	0.003
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.997	0.003
E72.0 Disorders of amino-acid transport	0.000	0.997	0.003
E73.9 Lactose intolerance, unspecified	0.000	0.997	0.003
E73.8 Other lactose intolerance	0.000	0.997	0.003
E73.1 Secondary lactase deficiency	0.000	0.997	0.003
E73.0 Congenital lactase deficiency	0.000	0.997	0.003
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.997	0.003
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.997	0.003
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.997	0.003
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.997	0.003
E74.2 Disorders of galactose metabolism	0.000	0.997	0.003
E74.1 Disorders of fructose metabolism	0.000	0.997	0.003
E74.0 Glycogen storage disease	0.000	0.997	0.003
E75.6 Lipid storage disorder, unspecified	0.000	0.997	0.003
E75.5 Other lipid storage disorders	0.000	0.997	0.003
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.997	0.003
E75.3 Sphingolipidosis, unspecified	0.000	0.997	0.003
E75.2 Other sphingolipidosis	0.000	0.997	0.003
E75.1 Other gangliosidosis	0.000	0.997	0.003
E75.0 GM2 gangliosidosis	0.000	0.997	0.003
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.997	0.003
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.997	0.003
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.997	0.003
E76.2 Other mucopolysaccharidoses	0.000	0.997	0.003
E76.1 Mucopolysaccharidosis, type II	0.000	0.997	0.003
E76.0 Mucopolysaccharidosis, type I	0.000	0.997	0.003
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.997	0.003
E77.8 Other disorders of glycoprotein metabolism	0.000	0.997	0.003
E77.1 Defects in glycoprotein degradation	0.000	0.997	0.003
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.997	0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.997	0.003
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.997	0.003
E79.1 Lesch-Nyhan syndrome	0.000	0.997	0.003
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.997	0.003
E84.9 Cystic fibrosis, unspecified	0.000	0.997	0.003
E84.8 Cystic fibrosis with other manifestations	0.000	0.997	0.003
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.997	0.003
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.997	0.003
E85.9 Amyloidosis, unspecified	0.000	0.997	0.003
E85.8 Other amyloidosis	0.000	0.997	0.003
E85.4 Organ-limited amyloidosis	0.000	0.997	0.003
E85.3 Secondary systemic amyloidosis	0.000	0.997	0.003
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.997	0.003
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.997	0.003
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.997	0.003
E15 Nondiabetic hypoglycaemic coma	0.000	0.997	0.003
E04.2 Non-toxic multinodular goitre	0.000	0.997	0.003
E87.7 Fluid overload	0.000	0.997	0.003
E28.9 Ovarian dysfunction, unspecified	0.000	0.997	0.002
E28.8 Other ovarian dysfunction	0.000	0.997	0.002
E28.3 Primary ovarian failure	0.000	0.997	0.002
E28.1 Androgen excess	0.000	0.997	0.002
E28.0 Oestrogen excess	0.000	0.997	0.002
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.997	0.002
E80.6 Other disorders of bilirubin metabolism	0.000	0.997	0.002
E80.5 Crigler-Najjar syndrome	0.000	0.997	0.002
E80.3 Defects of catalase and peroxydase	0.000	0.997	0.002
E80.2 Other porphyria	0.000	0.997	0.002
E80.1 Porphyria cutanea tarda	0.000	0.997	0.002
E80.0 Hereditary erythropoietic porphyria	0.000	0.997	0.002
E87.5 Hyperkalaemia	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.000	0.997	0.002
E20.8 Other hypoparathyroidism	0.000	0.997	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.997	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.997	0.002
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.997	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.997	0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.002
E22.1 Hyperprolactinaemia	0.000	0.997	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.002
E24.9 Cushing's syndrome, unspecified	0.000	0.997	0.002
E24.8 Other Cushing's syndrome	0.000	0.997	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.997	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.997	0.002
E24.2 Drug-induced Cushing's syndrome	0.000	0.997	0.002
E24.1 Nelson's syndrome	0.000	0.997	0.002
E24.0 Pituitary-dependent Cushing's disease	0.000	0.997	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.997	0.002
E25.8 Other adrenogenital disorders	0.000	0.997	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.997	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.997	0.002
E26.8 Other hyperaldosteronism	0.000	0.997	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.997	0.002
E26.0 Primary hyperaldosteronism	0.000	0.997	0.002
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.002
E27.8 Other specified disorders of adrenal gland	0.000	0.997	0.002
E27.5 Adrenomedullary hyperfunction	0.000	0.997	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.997	0.002
E27.2 Addisonian crisis	0.000	0.997	0.002
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.002
E27.0 Other adrenocortical overactivity	0.000	0.997	0.002
E29.9 Testicular dysfunction, unspecified	0.000	0.997	0.002
E29.8 Other testicular dysfunction	0.000	0.997	0.002
E29.1 Testicular hypofunction	0.000	0.997	0.002
E29.0 Testicular hyperfunction	0.000	0.997	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.997	0.002
E30.8 Other disorders of puberty	0.000	0.997	0.002
E30.1 Precocious puberty	0.000	0.997	0.002
E30.0 Delayed puberty	0.000	0.997	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.997	0.002
E31.8 Other polyglandular dysfunction	0.000	0.997	0.002
E31.1 Polyglandular hyperfunction	0.000	0.997	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.997	0.002
E32.9 Disease of thymus, unspecified	0.000	0.997	0.002
E32.8 Other diseases of thymus	0.000	0.997	0.002
E32.1 Abscess of thymus	0.000	0.997	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.997	0.002
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.002
E34.8 Other specified endocrine disorders	0.000	0.997	0.002
E34.5 Androgen resistance syndrome	0.000	0.997	0.002
E34.4 Constitutional tall stature	0.000	0.997	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.002
E34.0 Carcinoid syndrome	0.000	0.997	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.997	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.997	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.997	0.002
E16 Other disorders of pancreatic internal secretion	0.000	0.997	0.002
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.997	0.002
E63 Other nutritional deficiencies	0.000	0.997	0.002
E56 Other vitamin deficiencies	0.000	0.997	0.002
E51 Thiamine deficiency	0.000	0.997	0.002
E50 Vitamin A deficiency	0.000	0.997	0.002
E60 Dietary zinc deficiency	0.000	0.997	0.002
E59 Dietary selenium deficiency	0.000	0.997	0.002
E58 Dietary calcium deficiency	0.000	0.997	0.002
E54 Ascorbic acid deficiency	0.000	0.997	0.002
E52 Niacin deficiency [pellagra]	0.000	0.997	0.002
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.997	0.002
E87.4 Mixed disorder of acid-base balance	0.000	0.997	0.002
E87.3 Alkalosis	0.000	0.997	0.002
E06.3 Autoimmune thyroiditis	0.000	0.997	0.002
E80.4 Gilbert's syndrome	0.000	0.997	0.002
E55 Vitamin D deficiency	0.000	0.997	0.002
E87.0 Hyperosmolality and hypernatraemia	0.000	0.997	0.002
E53 Deficiency of other B group vitamins	0.000	0.997	0.002
E10-E14 Diabetes mellitus	0.000	0.998	0.002
E61 Deficiency of other nutrient elements	0.000	0.998	0.002
R94 Abnormal results of function studies	0.000	0.998	0.002
E44.1 Mild protein-energy malnutrition	0.000	0.998	0.002
E44.0 Moderate protein-energy malnutrition	0.000	0.998	0.002
Z03 Medical observation and evaluation for suspected diseases and conditions	0.000	0.998	0.002
Y84.8 Other medical procedures	0.002	0.998	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.998	0.002
R12 Heartburn	0.000	0.998	0.002
R94.3 Abnormal results of cardiovascular function studies	0.000	0.998	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.002
E16.3 Increased secretion of glucagon	0.000	0.998	0.002
E16.1 Other hypoglycaemia	0.000	0.998	0.002
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.002
Z03.5 Observation for other suspected cardiovascular diseases	0.000	0.998	0.002
Z03.4 Observation for suspected myocardial infarction	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.000	0.998	0.002
E50.8 Other manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.998	0.002
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.998	0.002
E50.5 Vitamin A deficiency with night blindness	0.000	0.998	0.002
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.998	0.002
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.998	0.002
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.998	0.002
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.998	0.002
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.998	0.002
E51.9 Thiamine deficiency, unspecified	0.000	0.998	0.002
E51.8 Other manifestations of thiamine deficiency	0.000	0.998	0.002
E51.2 Wernicke's encephalopathy	0.000	0.998	0.002
E51.1 Beriberi	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.000	0.998	0.002
E56.8 Deficiency of other vitamins	0.000	0.998	0.002
E56.1 Deficiency of vitamin K	0.000	0.998	0.002
E56.0 Deficiency of vitamin E	0.000	0.998	0.002
E63.9 Nutritional deficiency, unspecified	0.000	0.998	0.002
E63.8 Other specified nutritional deficiencies	0.000	0.998	0.002
E63.1 Imbalance of constituents of food intake	0.000	0.998	0.002
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.998	0.002
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.998	0.002
E64.8 Sequelae of other nutritional deficiencies	0.000	0.998	0.002
E64.3 Sequelae of rickets	0.000	0.998	0.002
E64.2 Sequelae of vitamin C deficiency	0.000	0.998	0.002
E64.1 Sequelae of vitamin A deficiency	0.000	0.998	0.002
E64.0 Sequelae of protein-energy malnutrition	0.000	0.998	0.002
E87.2 Acidosis	0.000	0.998	0.002
E55.0 Rickets, active	0.000	0.998	0.002
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.998	0.002
E53.9 Vitamin B deficiency, unspecified	0.000	0.998	0.002
E53.1 Pyridoxine deficiency	0.000	0.998	0.002
E53.0 Riboflavin deficiency	0.000	0.998	0.002
E55.9 Vitamin D deficiency, unspecified	0.000	0.998	0.002
Y84.2 Radiological procedure and radiotherapy	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.000	0.998	0.002
E12 Malnutrition-related diabetes mellitus	0.000	0.998	0.002
E61.9 Deficiency of nutrient element, unspecified	0.000	0.998	0.002
E61.8 Deficiency of other specified nutrient elements	0.000	0.998	0.002
E61.7 Deficiency of multiple nutrient elements	0.000	0.998	0.002
E61.6 Vanadium deficiency	0.000	0.998	0.002
E61.5 Molybdenum deficiency	0.000	0.998	0.002
E61.4 Chromium deficiency	0.000	0.998	0.002
E61.3 Manganese deficiency	0.000	0.998	0.002
E61.2 Magnesium deficiency	0.000	0.998	0.002
E61.0 Copper deficiency	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.000	0.998	0.002
E53.8 Deficiency of other specified B group vitamins	0.000	0.998	0.002
R94.8 Abnormal results of function studies of other organs and systems	0.000	0.998	0.002
R94.7 Abnormal results of other endocrine function studies	0.000	0.998	0.002
R94.6 Abnormal results of thyroid function studies	0.000	0.998	0.002
R94.4 Abnormal results of kidney function studies	0.000	0.998	0.002
R94.2 Abnormal results of pulmonary function studies	0.000	0.998	0.002
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.000	0.998	0.002
R94.0 Abnormal results of function studies of central nervous system	0.000	0.998	0.002
Z03.6 Observation for suspected toxic effect from ingested substance	0.000	0.998	0.002
Z03.3 Observation for suspected nervous system disorder	0.000	0.998	0.002
Z03.2 Observation for suspected mental and behavioural disorders	0.000	0.998	0.002
Z03.0 Observation for suspected tuberculosis	0.000	0.998	0.002
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.998	0.002
E61.1 Iron deficiency	0.000	0.998	0.001
Z03.1 Observation for suspected malignant neoplasm	0.000	0.998	0.002
E10 Insulin-dependent diabetes mellitus	0.000	0.998	0.002
N17.9 Acute renal failure, unspecified	0.000	0.998	0.002
E14 Unspecified diabetes mellitus	0.000	0.998	0.002
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.998	0.002
E12.9 Without complications	0.000	0.998	0.001
E12.8 With unspecified complications	0.000	0.998	0.001
E12.7 With multiple complications	0.000	0.998	0.001
E12.6 With other specified complications	0.000	0.998	0.001
E12.5 With peripheral circulatory complications	0.000	0.998	0.001
E12.4 With neurological complications	0.000	0.998	0.001
E12.3 With ophthalmic complications	0.000	0.998	0.001
E12.2 With renal complications	0.000	0.998	0.001
E12.1 With ketoacidosis	0.000	0.998	0.001
E12.0 With coma	0.000	0.998	0.001
E13.9 Without complications	0.000	0.998	0.001
E13.8 With unspecified complications	0.000	0.998	0.001
E13.7 With multiple complications	0.000	0.998	0.001
E13.6 With other specified complications	0.000	0.998	0.001
E13.5 With peripheral circulatory complications	0.000	0.998	0.001
E13.4 With neurological complications	0.000	0.998	0.001
E13.3 With ophthalmic complications	0.000	0.998	0.001
E13.2 With renal complications	0.000	0.998	0.001
E13.1 With ketoacidosis	0.000	0.998	0.001
E13.0 With coma	0.000	0.998	0.001
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.998	0.002
H40.9 Glaucoma, unspecified	0.000	0.998	0.002
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.998	0.001
E78.8 Other disorders of lipoprotein metabolism	0.000	0.998	0.001
E78.6 Lipoprotein deficiency	0.000	0.998	0.001
E78.4 Other hyperlipidaemia	0.000	0.998	0.001
E78.3 Hyperchylomicronaemia	0.000	0.998	0.001
E78.2 Mixed hyperlipidaemia	0.000	0.998	0.001
E78.1 Pure hyperglyceridaemia	0.000	0.998	0.001
E10.3 With ophthalmic complications	0.000	0.998	0.001
K82.8 Other specified diseases of gallbladder	0.000	0.998	0.002
E10.8 With unspecified complications	0.000	0.998	0.001
E10.7 With multiple complications	0.000	0.998	0.001
E10.6 With other specified complications	0.000	0.998	0.001
E10.5 With peripheral circulatory complications	0.000	0.998	0.001
E10.4 With neurological complications	0.000	0.998	0.001
E10.2 With renal complications	0.000	0.998	0.001
E10.0 With coma	0.000	0.998	0.001
E14.8 With unspecified complications	0.000	0.998	0.001
E14.7 With multiple complications	0.000	0.998	0.001
E14.6 With other specified complications	0.000	0.998	0.001
E14.5 With peripheral circulatory complications	0.000	0.998	0.001
E14.4 With neurological complications	0.000	0.998	0.001
E14.3 With ophthalmic complications	0.000	0.998	0.001
E14.2 Withrenal complications	0.000	0.998	0.001
E14.1 With ketoacidosis	0.000	0.998	0.001
E14.0 With coma	0.000	0.998	0.001
E11 Non-insulin-dependent diabetes mellitus	0.000	0.998	0.002
R47.8 Other and unspecified speech disturbances	0.001	0.998	0.000
W19.9 Unspecified place	0.000	0.998	0.002
Y84.0 Cardiac catheterisation	0.001	0.998	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
Y84.9 Medical procedure, unspecified	0.001	0.998	0.000
Y84.7 Blood-sampling	0.001	0.998	0.000
Y84.5 Insertion of gastric or duodenal sound	0.001	0.998	0.000
Y84.4 Aspiration of fluid	0.001	0.998	0.000
Y84.3 Shock therapy	0.001	0.998	0.000
Y84.1 Kidney dialysis	0.001	0.998	0.000
E10.1 With ketoacidosis	0.000	0.998	0.001
C77.3 Axillary and upper limb lymph nodes	0.000	0.999	0.001
G81.9 Hemiplegia, unspecified	0.001	0.999	0.000
E11.4 With neurological complications	0.000	0.999	0.001
Y84.6 Urinary catheterisation	0.001	0.999	0.000
E11.8 With unspecified complications	0.000	0.999	0.001
E11.7 With multiple complications	0.000	0.999	0.001
E11.6 With other specified complications	0.000	0.999	0.001
E11.2 With renal complications	0.000	0.999	0.001
E11.1 With ketoacidosis	0.000	0.999	0.001
E11.0 With coma	0.000	0.999	0.001
Z53.9 Procedure not carried out, unspecified reason	0.000	0.999	0.001
E11.5 With peripheral circulatory complications	0.000	0.999	0.001
R10.1 Pain localised to upper abdomen	0.000	0.999	0.001
E10.9 Without complications	0.000	0.999	0.001
Z01.8 Other specified special examinations	0.000	0.999	0.001
O36.6 Maternal care for excessive foetal growth	0.001	0.999	0.000
E11.3 With ophthalmic complications	0.000	0.999	0.001
Z00.0 General medical examination	0.000	0.999	0.001
G40.9 Epilepsy, unspecified	0.001	0.999	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.999	0.001
Z04.8 Examination and observation for other specified reasons	0.000	0.999	0.001
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.000	0.999	0.001
D37.4 Colon	0.001	0.999	0.000
E14.9 Without complications	0.000	0.999	0.001
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.999	0.001
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.000	0.999	0.001
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.001	0.999	0.000
H53.2 Diplopia	0.001	0.999	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.999	0.001
O36.9 Maternal care for foetal problem, unspecified	0.001	0.999	0.000
W19.4 Street and highway	0.000	0.999	0.001
Z04 Examination and observation for other reasons	0.000	0.999	0.001
H33.0 Retinal detachment with retinal break	0.001	0.999	0.000
H52.1 Myopia	0.001	0.999	0.000
Z01.9 Special examination, unspecified	0.000	0.999	0.001
Z01.7 Laboratory examination	0.000	0.999	0.001
Z01.4 Gynaecological examination (general)(routine)	0.000	0.999	0.001
Z01.3 Examination of blood pressure	0.000	0.999	0.001
Z01.2 Dental examination	0.000	0.999	0.001
Z01.1 Examination of ears and hearing	0.000	0.999	0.001
Z01.0 Examination of eyes and vision	0.000	0.999	0.001
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.999	0.001
G81 Hemiplegia	0.001	0.999	0.000
W19 Unspecified fall	0.000	0.999	0.001
E78.0 Pure hypercholesterolaemia	0.000	0.999	0.001
O36.8 Maternal care for other specified foetal problems	0.001	0.999	0.000
Z00.8 Other general examinations	0.000	0.999	0.001
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.999	0.001
Z00.5 Examination of potential donor of organ and tissue	0.000	0.999	0.001
Z00.4 General psychiatric examination, not elsewhere classified	0.000	0.999	0.001
Z00.3 Examination for adolescent development state	0.000	0.999	0.001
Z00.2 Examination for period of rapid growth in childhood	0.000	0.999	0.001
Z00.1 Routine child health examination	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations