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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10484401
log Bayes Factor = 80.8798
Chromosome 6   position 27,746,590  (GRCh37) Explore rs10484401 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
N40 Hyperplasia of prostate
0.000 0.004 0.996
E16 Other disorders of pancreatic internal secretion
0.995 0.005 0.000
E16.2 Hypoglycaemia, unspecified
0.994 0.006 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.009 0.991
E03 Other hypothyroidism
0.990 0.010 0.000
E14 Unspecified diabetes mellitus
0.987 0.013 0.000
E03.9 Hypothyroidism, unspecified
0.982 0.018 0.000
E14.3 With ophthalmic complications
0.940 0.060 0.000
E10.2 With renal complications
0.937 0.063 0.000
E20-E35 Disorders of other endocrine glands
0.935 0.065 0.000
E10.3 With ophthalmic complications
0.908 0.092 0.000
E23 Hypofunction and other disorders of pituitary gland
0.903 0.097 0.000
E10.1 With ketoacidosis
0.896 0.104 0.000
E10.6 With other specified complications
0.865 0.135 0.000
K40 Inguinal hernia
0.000 0.154 0.846
E10.4 With neurological complications
0.840 0.160 0.000
E07 Other disorders of thyroid
0.839 0.161 0.000
E23.2 Diabetes insipidus
0.838 0.162 0.000
E14.6 With other specified complications
0.835 0.165 0.000
E10.7 With multiple complications
0.828 0.172 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.180 0.820
E05.0 Thyrotoxicosis with diffuse goitre
0.817 0.183 0.000
E14.9 Without complications
0.804 0.196 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.793 0.207 0.000
E23.0 Hypopituitarism
0.792 0.208 0.000
E27 Other disorders of adrenal gland
0.789 0.211 0.000
K90 Intestinal malabsorption
0.779 0.221 0.000
E10.5 With peripheral circulatory complications
0.765 0.235 0.000
E10.0 With coma
0.765 0.235 0.000
E14.4 With neurological complications
0.762 0.238 0.000
E14.2 Withrenal complications
0.755 0.245 0.000
E27.1 Primary adrenocortical insufficiency
0.751 0.249 0.000
E11 Non-insulin-dependent diabetes mellitus
0.750 0.250 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.730 0.270 0.000
E31 Polyglandular dysfunction
0.728 0.272 0.000
E24 Cushing's syndrome
0.727 0.272 0.000
E14.5 With peripheral circulatory complications
0.725 0.275 0.000
E10.8 With unspecified complications
0.724 0.276 0.000
E11.5 With peripheral circulatory complications
0.724 0.276 0.000
E14.8 With unspecified complications
0.724 0.276 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.722 0.278 0.000
E16.1 Other hypoglycaemia
0.721 0.279 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.714 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.714 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.714 0.286 0.000
E16.3 Increased secretion of glucagon
0.714 0.286 0.000
E23.7 Disorder of pituitary gland, unspecified
0.712 0.288 0.000
E14.1 With ketoacidosis
0.710 0.290 0.000
E03.5 Myxoedema coma
0.709 0.290 0.000
E03.4 Atrophy of thyroid (acquired)
0.709 0.290 0.000
E03.3 Postinfectious hypothyroidism
0.709 0.290 0.000
E03.1 Congenital hypothyroidism without goitre
0.709 0.290 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.709 0.290 0.000
E11.3 With ophthalmic complications
0.708 0.292 0.000
E14.7 With multiple complications
0.707 0.292 0.000
E14.0 With coma
0.707 0.292 0.000
E20 Hypoparathyroidism
0.706 0.293 0.000
E03.8 Other specified hypothyroidism
0.689 0.310 0.000
E40-E46 Malnutrition
0.689 0.311 0.000
E07.8 Other specified disorders of thyroid
0.685 0.315 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.673 0.327 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.670 0.330 0.000
E32 Diseases of thymus
0.670 0.330 0.000
E30 Disorders of puberty, not elsewhere classified
0.670 0.330 0.000
E34 Other endocrine disorders
0.668 0.332 0.000
E07.9 Disorder of thyroid, unspecified
0.660 0.340 0.000
E13 Other specified diabetes mellitus
0.659 0.341 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.657 0.343 0.000
E25 Adrenogenital disorders
0.653 0.347 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.647 0.352 0.000
E23.1 Drug-induced hypopituitarism
0.647 0.352 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.368 0.632
E23.6 Other disorders of pituitary gland
0.628 0.372 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.610 0.389 0.000
K90.9 Intestinal malabsorption, unspecified
0.608 0.392 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.394 0.606
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.394 0.606
E11.6 With other specified complications
0.603 0.397 0.000
E29 Testicular dysfunction
0.603 0.397 0.000
E07.1 Dyshormogenetic goitre
0.601 0.399 0.000
E07.0 Hypersecretion of calcitonin
0.601 0.399 0.000
E24.2 Drug-induced Cushing's syndrome
0.599 0.401 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.599 0.401 0.000
E05.8 Other thyrotoxicosis
0.594 0.406 0.000
E27.2 Addisonian crisis
0.589 0.411 0.000
E31.0 Autoimmune polyglandular failure
0.580 0.420 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.577 0.423 0.000
E50-E64 Other nutritional deficiencies
0.575 0.425 0.000
E27.5 Adrenomedullary hyperfunction
0.566 0.434 0.000
E27.0 Other adrenocortical overactivity
0.566 0.434 0.000
K90.3 Pancreatic steatorrhoea
0.558 0.442 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.558 0.442 0.000
K90.1 Tropical sprue
0.558 0.442 0.000
E28 Ovarian dysfunction
0.556 0.444 0.000
N40-N51 Diseases of male genital organs
0.000 0.445 0.555
N41 Inflammatory diseases of prostate
0.000 0.452 0.548
E20.9 Hypoparathyroidism, unspecified
0.543 0.457 0.000
E06 Thyroiditis
0.542 0.458 0.000
E24.0 Pituitary-dependent Cushing's disease
0.542 0.458 0.000
E11.7 With multiple complications
0.537 0.462 0.000
E11.0 With coma
0.534 0.466 0.000
K90.8 Other intestinal malabsorption
0.532 0.468 0.000
E13.3 With ophthalmic complications
0.524 0.476 0.000
E31.9 Polyglandular dysfunction, unspecified
0.522 0.478 0.000
E31.8 Other polyglandular dysfunction
0.522 0.478 0.000
E31.1 Polyglandular hyperfunction
0.522 0.478 0.000
E24.8 Other Cushing's syndrome
0.522 0.478 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.522 0.478 0.000
E24.3 Ectopic ACTH syndrome
0.522 0.478 0.000
E24.1 Nelson's syndrome
0.522 0.478 0.000
E34.8 Other specified endocrine disorders
0.520 0.479 0.000
E26 Hyperaldosteronism
0.515 0.484 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
N41.1 Chronic prostatitis
0.000 0.487 0.513
E21.3 Hyperparathyroidism, unspecified
0.512 0.488 0.000
N45 Orchitis and epididymitis
0.000 0.488 0.512
E20.8 Other hypoparathyroidism
0.506 0.493 0.000
E20.1 Pseudohypoparathyroidism
0.506 0.493 0.000
E20.0 Idiopathic hypoparathyroidism
0.506 0.493 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.499 0.501
E21.2 Other hyperparathyroidism
0.497 0.503 0.000
E22 Hyperfunction of pituitary gland
0.495 0.505 0.000
E34.9 Endocrine disorder, unspecified
0.495 0.505 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.494 0.506 0.000
E45 Retarded development following protein-energy malnutrition
0.494 0.506 0.000
E43 Unspecified severe protein-energy malnutrition
0.494 0.506 0.000
E42 Marasmic kwashiorkor
0.494 0.506 0.000
E41 Nutritional marasmus
0.494 0.506 0.000
E40 Kwashiorkor
0.494 0.506 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.510 0.490
E21.5 Disorder of parathyroid gland, unspecified
0.483 0.517 0.000
E21.4 Other specified disorders of parathyroid gland
0.483 0.517 0.000
N41.0 Acute prostatitis
0.000 0.518 0.482
E30.9 Disorder of puberty, unspecified
0.480 0.519 0.000
E30.8 Other disorders of puberty
0.480 0.519 0.000
E30.1 Precocious puberty
0.480 0.519 0.000
E30.0 Delayed puberty
0.480 0.519 0.000
E32.9 Disease of thymus, unspecified
0.480 0.519 0.000
E32.8 Other diseases of thymus
0.480 0.519 0.000
E32.1 Abscess of thymus
0.480 0.519 0.000
E32.0 Persistent hyperplasia of thymus
0.480 0.519 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.480 0.519 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.480 0.519 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.480 0.519 0.000
E34.5 Androgen resistance syndrome
0.479 0.521 0.000
E34.4 Constitutional tall stature
0.479 0.521 0.000
E34.3 Short stature, not elsewhere classified
0.479 0.521 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.479 0.521 0.000
E34.1 Other hypersecretion of intestinal hormones
0.479 0.521 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.474 0.526 0.000
E13.8 With unspecified complications
0.473 0.527 0.000
E13.7 With multiple complications
0.473 0.527 0.000
E13.6 With other specified complications
0.473 0.527 0.000
E13.5 With peripheral circulatory complications
0.473 0.527 0.000
E13.4 With neurological complications
0.473 0.527 0.000
E13.2 With renal complications
0.473 0.527 0.000
E13.1 With ketoacidosis
0.473 0.527 0.000
E13.0 With coma
0.473 0.527 0.000
E25.9 Adrenogenital disorder, unspecified
0.468 0.532 0.000
E25.8 Other adrenogenital disorders
0.468 0.532 0.000
E11.8 With unspecified complications
0.468 0.532 0.000
E27.9 Disorder of adrenal gland, unspecified
0.467 0.533 0.000
E46 Unspecified protein-energy malnutrition
0.466 0.534 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.536 0.464
E24.9 Cushing's syndrome, unspecified
0.463 0.537 0.000
N46 Male infertility
0.000 0.539 0.461
E53 Deficiency of other B group vitamins
0.457 0.543 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.451 0.549 0.000
E21.0 Primary hyperparathyroidism
0.445 0.555 0.000
N44 Torsion of testis
0.000 0.557 0.443
E29.9 Testicular dysfunction, unspecified
0.432 0.568 0.000
E29.8 Other testicular dysfunction
0.432 0.568 0.000
E29.0 Testicular hyperfunction
0.432 0.568 0.000
E11.1 With ketoacidosis
0.429 0.571 0.000
E51 Thiamine deficiency
0.420 0.580 0.000
E58 Dietary calcium deficiency
0.415 0.585 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.412 0.588 0.000
E63 Other nutritional deficiencies
0.412 0.588 0.000
E56 Other vitamin deficiencies
0.412 0.588 0.000
E50 Vitamin A deficiency
0.412 0.588 0.000
E60 Dietary zinc deficiency
0.412 0.588 0.000
E59 Dietary selenium deficiency
0.412 0.588 0.000
E54 Ascorbic acid deficiency
0.412 0.588 0.000
E52 Niacin deficiency [pellagra]
0.412 0.588 0.000
E22.1 Hyperprolactinaemia
0.407 0.593 0.000
N42 Other disorders of prostate
0.000 0.595 0.405
E34.0 Carcinoid syndrome
0.402 0.598 0.000
E28.9 Ovarian dysfunction, unspecified
0.399 0.601 0.000
E28.8 Other ovarian dysfunction
0.399 0.601 0.000
E28.1 Androgen excess
0.399 0.601 0.000
E28.0 Oestrogen excess
0.399 0.601 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.602 0.398
E53.8 Deficiency of other specified B group vitamins
0.395 0.605 0.000
N41.3 Prostatocystitis
0.000 0.607 0.393
N41.2 Abscess of prostate
0.000 0.607 0.393
E28.3 Primary ovarian failure
0.393 0.607 0.000
E06.5 Other chronic thyroiditis
0.389 0.611 0.000
E06.4 Drug-induced thyroiditis
0.389 0.611 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.389 0.611 0.000
E06.1 Subacute thyroiditis
0.389 0.611 0.000
E06.0 Acute thyroiditis
0.389 0.611 0.000
E06.9 Thyroiditis, unspecified
0.387 0.613 0.000
N42.8 Other specified disorders of prostate
0.000 0.624 0.376
E26.9 Hyperaldosteronism, unspecified
0.370 0.630 0.000
E26.8 Other hyperaldosteronism
0.370 0.630 0.000
E26.1 Secondary hyperaldosteronism
0.370 0.630 0.000
E29.1 Testicular hypofunction
0.364 0.635 0.000
E65-E68 Obesity and other hyperalimentation
0.362 0.638 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.355 0.645 0.000
E22.8 Other hyperfunction of pituitary gland
0.355 0.645 0.000
E44.1 Mild protein-energy malnutrition
0.354 0.645 0.000
E44.0 Moderate protein-energy malnutrition
0.354 0.645 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.647 0.353
N41.8 Other inflammatory diseases of prostate
0.000 0.658 0.342
E53.1 Pyridoxine deficiency
0.328 0.672 0.000
E53.0 Riboflavin deficiency
0.328 0.672 0.000
E13.9 Without complications
0.322 0.678 0.000
E55 Vitamin D deficiency
0.316 0.684 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.687 0.313
E51.2 Wernicke's encephalopathy
0.309 0.691 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.695 0.304
E51.9 Thiamine deficiency, unspecified
0.301 0.698 0.000
E51.8 Other manifestations of thiamine deficiency
0.301 0.698 0.000
E51.1 Beriberi
0.301 0.698 0.000
E50.9 Vitamin A deficiency, unspecified
0.296 0.704 0.000
E50.8 Other manifestations of vitamin A deficiency
0.296 0.704 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.296 0.704 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.296 0.704 0.000
E50.5 Vitamin A deficiency with night blindness
0.296 0.704 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.296 0.704 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.296 0.704 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.296 0.704 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.296 0.704 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.296 0.704 0.000
E56.9 Vitamin deficiency, unspecified
0.296 0.704 0.000
E56.8 Deficiency of other vitamins
0.296 0.704 0.000
E56.1 Deficiency of vitamin K
0.296 0.704 0.000
E56.0 Deficiency of vitamin E
0.296 0.704 0.000
E63.9 Nutritional deficiency, unspecified
0.296 0.704 0.000
E63.8 Other specified nutritional deficiencies
0.296 0.704 0.000
E63.1 Imbalance of constituents of food intake
0.296 0.704 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.296 0.704 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.296 0.704 0.000
E64.8 Sequelae of other nutritional deficiencies
0.296 0.704 0.000
E64.3 Sequelae of rickets
0.296 0.704 0.000
E64.2 Sequelae of vitamin C deficiency
0.296 0.704 0.000
E64.1 Sequelae of vitamin A deficiency
0.296 0.704 0.000
E64.0 Sequelae of protein-energy malnutrition
0.296 0.704 0.000
E28.2 Polycystic ovarian syndrome
0.295 0.705 0.000
E61 Deficiency of other nutrient elements
0.292 0.708 0.000
N42.3 Dysplasia of prostate
0.000 0.710 0.290
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.714 0.285
N51.2 Balanitis in diseases classified elsewhere
0.000 0.714 0.285
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.714 0.285
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.714 0.285
E53.9 Vitamin B deficiency, unspecified
0.284 0.716 0.000
N42.0 Calculus of prostate
0.000 0.719 0.281
E22.0 Acromegaly and pituitary gigantism
0.266 0.734 0.000
E67 Other hyperalimentation
0.259 0.740 0.000
E68 Sequelae of hyperalimentation
0.259 0.740 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.741 0.258
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.747 0.253
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.747 0.253
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.747 0.253
E11.2 With renal complications
0.238 0.762 0.000
E55.0 Rickets, active
0.227 0.773 0.000
N42.2 Atrophy of prostate
0.000 0.781 0.219
E06.3 Autoimmune thyroiditis
0.218 0.782 0.000
E26.0 Primary hyperaldosteronism
0.215 0.784 0.001
E61.9 Deficiency of nutrient element, unspecified
0.209 0.790 0.000
E61.8 Deficiency of other specified nutrient elements
0.209 0.790 0.000
E61.7 Deficiency of multiple nutrient elements
0.209 0.790 0.000
E61.6 Vanadium deficiency
0.209 0.790 0.000
E61.5 Molybdenum deficiency
0.209 0.790 0.000
E61.4 Chromium deficiency
0.209 0.790 0.000
E61.3 Manganese deficiency
0.209 0.790 0.000
E61.0 Copper deficiency
0.209 0.790 0.000
E65 Localised adiposity
0.207 0.792 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.801 0.199
E27.8 Other specified disorders of adrenal gland
0.196 0.801 0.003
N43 Hydrocele and spermatocele
0.000 0.807 0.193
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.189 0.811 0.000
E67.8 Other specified hyperalimentation
0.186 0.814 0.000
E67.3 Hypervitaminosis D
0.186 0.814 0.000
E67.2 Megavitamin-B6 syndrome
0.186 0.814 0.000
E67.1 Hypercarotenaemia
0.186 0.814 0.000
E67.0 Hypervitaminosis A
0.186 0.814 0.000
K40-K46 Hernia
0.000 0.827 0.173
K44 Diaphragmatic hernia
0.000 0.834 0.166
E61.1 Iron deficiency
0.164 0.836 0.000
E61.2 Magnesium deficiency
0.161 0.839 0.001
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.840 0.160
E04 Other non-toxic goitre
0.150 0.850 0.000
N43.2 Other hydrocele
0.000 0.861 0.138
N43.1 Infected hydrocele
0.000 0.861 0.138
N43.0 Encysted hydrocele
0.000 0.861 0.138
E55.9 Vitamin D deficiency, unspecified
0.130 0.870 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.878 0.122
K44.1 Diaphragmatic hernia with gangrene
0.000 0.881 0.119
K41 Femoral hernia
0.000 0.888 0.112
N43.4 Spermatocele
0.000 0.889 0.111
K46 Unspecified abdominal hernia
0.000 0.890 0.110
E04.8 Other specified non-toxic goitre
0.108 0.892 0.000
E11.4 With neurological complications
0.099 0.900 0.001
N50 Other disorders of male genital organs
0.000 0.901 0.099
N42.9 Disorder of prostate, unspecified
0.000 0.901 0.099
E04.9 Non-toxic goitre, unspecified
0.097 0.903 0.000
E04.0 Non-toxic diffuse goitre
0.095 0.905 0.000
E83 Disorders of mineral metabolism
0.003 0.909 0.088
N84.1 Polyp of cervix uteri
0.000 0.912 0.088
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.912 0.088
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.919 0.081
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.919 0.081
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.919 0.081
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.919 0.081
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.921 0.079
K45 Other abdominal hernia
0.000 0.923 0.077
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.923 0.077
K42 Umbilical hernia
0.000 0.925 0.075
N50.9 Disorder of male genital organs, unspecified
0.000 0.929 0.071
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.932 0.067
N50.0 Atrophy of testis
0.000 0.933 0.067
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.934 0.066
E83.9 Disorder of mineral metabolism, unspecified
0.002 0.935 0.063
E83.8 Other disorders of mineral metabolism
0.002 0.935 0.063
E83.2 Disorders of zinc metabolism
0.002 0.935 0.063
E83.0 Disorders of copper metabolism
0.002 0.935 0.063
E83.3 Disorders of phosphorus metabolism
0.001 0.936 0.063
K90-K93 Other diseases of the digestive system
0.060 0.940 0.000
E66 Obesity
0.058 0.942 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.943 0.057
K45.1 Other specified abdominal hernia with gangrene
0.000 0.945 0.055
K42.1 Umbilical hernia with gangrene
0.000 0.946 0.054
K42.0 Umbilical hernia with obstruction, without gangrene
0.000 0.947 0.053
K43 Ventral hernia
0.000 0.950 0.050
K93 Disorders of other digestive organs in diseases classified elsewhere
0.043 0.957 0.000
E66.1 Drug-induced obesity
0.041 0.958 0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.961 0.038
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.001 0.962 0.037
E66.0 Obesity due to excess calories
0.037 0.963 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.036 0.964 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.964 0.036
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.964 0.036
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.964 0.036
K43.4 Parastomal hernia with gangrene
0.000 0.964 0.036
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.964 0.036
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.964 0.036
K43.1 Ventral hernia with gangrene
0.000 0.964 0.036
E11.9 Without complications
0.034 0.966 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.031 0.969 0.000
K93.1 Megacolon in Chagas' disease
0.031 0.969 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.031 0.969 0.000
N48 Other disorders of penis
0.000 0.971 0.029
E83.4 Disorders of magnesium metabolism
0.002 0.971 0.027
R47.0 Dysphasia and aphasia
0.028 0.972 0.000
E04.1 Non-toxic single thyroid nodule
0.027 0.973 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.977 0.023
E04.2 Non-toxic multinodular goitre
0.022 0.977 0.000
N48.4 Impotence of organic origin
0.000 0.978 0.022
N48.2 Other inflammatory disorders of penis
0.000 0.978 0.022
N43.3 Hydrocele, unspecified
0.000 0.981 0.019
E66.8 Other obesity
0.019 0.981 0.000
N48.1 Balanoposthitis
0.000 0.981 0.019
N48.0 Leukoplakia of penis
0.000 0.981 0.019
N48.5 Ulcer of penis
0.000 0.981 0.019
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.982 0.018
K60.2 Anal fissure, unspecified
0.018 0.982 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.983 0.017
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.017 0.983 0.000
K75.4 Autoimmune hepatitis
0.017 0.983 0.000
N50.1 Vascular disorders of male genital organs
0.000 0.984 0.016
N48.3 Priapism
0.000 0.985 0.015
K91.9 Postprocedural disorder of digestive system, unspecified
0.014 0.986 0.000
A04 Other bacterial intestinal infections
0.000 0.986 0.014
E83.5 Disorders of calcium metabolism
0.001 0.986 0.013
K75.8 Other specified inflammatory liver diseases
0.013 0.987 0.000
K75 Other inflammatory liver diseases
0.012 0.988 0.000
R47 Speech disturbances, not elsewhere classified
0.012 0.988 0.000
E70-E90 Metabolic disorders
0.011 0.988 0.001
K91.3 Postoperative intestinal obstruction
0.012 0.988 0.000
A04.8 Other specified bacterial intestinal infections
0.000 0.988 0.012
K91.1 Postgastric surgery syndromes
0.012 0.988 0.000
N48.9 Disorder of penis, unspecified
0.000 0.988 0.012
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.988 0.012
K91.4 Colostomy and enterostomy malfunction
0.011 0.989 0.000
K31.7 Polyp of stomach and duodenum
0.000 0.989 0.011
R47.1 Dysarthria and anarthria
0.011 0.989 0.000
K60 Fissure and fistula of anal and rectal regions
0.011 0.989 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.011 0.989 0.000
A04.9 Bacterial intestinal infection, unspecified
0.000 0.990 0.010
K60.1 Chronic anal fissure
0.010 0.990 0.000
K75.9 Inflammatory liver disease, unspecified
0.010 0.990 0.000
A04.4 Other intestinal Escherichia coli infections
0.000 0.990 0.010
A04.6 Enteritis due to Yersinia enterocolitica
0.000 0.990 0.010
A04.3 Enterohaemorrhagic Escherichia coli infection
0.000 0.990 0.010
A04.2 Enteroinvasive Escherichia coli infection
0.000 0.990 0.010
A04.1 Enterotoxigenic Escherichia coli infection
0.000 0.990 0.010
A04.0 Enteropathogenic Escherichia coli infection
0.000 0.990 0.010
K91.5 Postcholecystectomy syndrome
0.010 0.990 0.000
E85 Amyloidosis
0.009 0.990 0.001
S92.30 Fracture of metatarsal bone (closed)
0.010 0.990 0.000
K60.5 Anorectal fistula
0.010 0.990 0.000
S92.3 Fracture of metatarsal bone
0.010 0.990 0.000
S92 Fracture of foot, except ankle
0.010 0.990 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.000 0.990 0.010
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.008 0.991 0.001
K75.3 Granulomatous hepatitis, not elsewhere classified
0.009 0.991 0.000
K75.2 Nonspecific reactive hepatitis
0.009 0.991 0.000
K75.1 Phlebitis of portal vein
0.009 0.991 0.000
E84 Cystic fibrosis
0.008 0.991 0.001
K91.0 Vomiting following gastro-intestinal surgery
0.009 0.991 0.000
E77 Disorders of glycoprotein metabolism
0.008 0.991 0.001
E76 Disorders of glycosaminoglycan metabolism
0.008 0.991 0.001
E72 Other disorders of amino-acid metabolism
0.008 0.991 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.008 0.991 0.001
E70 Disorders of aromatic amino-acid metabolism
0.008 0.991 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.008 0.991 0.001
E85.4 Organ-limited amyloidosis
0.009 0.991 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.009 0.991 0.000
K31.4 Gastric diverticulum
0.000 0.991 0.009
M47.99 Spondylosis, unspecified (Site unspecified)
0.000 0.991 0.009
A04.5 Campylobacter enteritis
0.000 0.991 0.009
S90-S99 Injuries to the ankle and foot
0.009 0.991 0.000
E74 Other disorders of carbohydrate metabolism
0.008 0.991 0.001
E79 Disorders of purine and pyrimidine metabolism
0.007 0.991 0.001
K60.4 Rectal fistula
0.008 0.992 0.000
S93.0 Dislocation of ankle joint
0.008 0.992 0.000
S92.4 Fracture of great toe
0.008 0.992 0.000
E73 Lactose intolerance
0.007 0.992 0.001
S93.1 Dislocation of toe(s)
0.008 0.992 0.000
S92.1 Fracture of talus
0.008 0.992 0.000
N48.8 Other specified disorders of penis
0.000 0.992 0.008
S99 Other and unspecified injuries of ankle and foot
0.008 0.992 0.000
K31 Other diseases of stomach and duodenum
0.000 0.992 0.008
S92.0 Fracture of calcaneus
0.007 0.992 0.000
S99.9 Unspecified injury of ankle and foot
0.007 0.993 0.000
S93.3 Dislocation of other and unspecified parts of foot
0.007 0.993 0.000
E85.8 Other amyloidosis
0.007 0.993 0.001
E85.2 Heredofamilial amyloidosis, unspecified
0.007 0.993 0.001
E85.1 Neuropathic heredofamilial amyloidosis
0.007 0.993 0.001
E85.0 Nonneuropathic heredofamilial amyloidosis
0.007 0.993 0.001
S92.40 Fracture of great toe (closed)
0.007 0.993 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.007 0.993 0.000
S92.2 Fracture of other tarsal bone(s)
0.007 0.993 0.000
E75.5 Other lipid storage disorders
0.006 0.993 0.001
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.993 0.007
S91 Open wound of ankle and foot
0.007 0.993 0.000
S92.31 Fracture of metatarsal bone (open)
0.007 0.993 0.000
S92.9 Fracture of foot, unspecified
0.007 0.993 0.000
E84.9 Cystic fibrosis, unspecified
0.006 0.993 0.001
S97 Crushing injury of ankle and foot
0.007 0.993 0.000
E75.6 Lipid storage disorder, unspecified
0.006 0.993 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.006 0.993 0.001
E75.3 Sphingolipidosis, unspecified
0.006 0.993 0.001
E75.2 Other sphingolipidosis
0.006 0.993 0.001
E75.1 Other gangliosidosis
0.006 0.993 0.001
E75.0 GM2 gangliosidosis
0.006 0.993 0.001
S92.10 Fracture of talus (closed)
0.007 0.993 0.000
E84.8 Cystic fibrosis with other manifestations
0.006 0.993 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.006 0.993 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.006 0.993 0.001
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.006 0.993 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.006 0.993 0.001
E70.3 Albinism
0.006 0.993 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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