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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10484566
log Bayes Factor = 17.6082
Chromosome 6   position 32,835,258  (GRCh37) Explore rs10484566 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M75 Shoulder lesions
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
M75.4 Impingement syndrome of shoulder
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
E10.1 With ketoacidosis
0.997 0.003 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
H30-H36 Disorders of choroid and retina
0.994 0.006 0.000
H36.0 Diabetic retinopathy
0.994 0.006 0.000
H36 Retinal disorders in diseases classified elsewhere
0.994 0.006 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.979 0.021 0.000
M45-M49 Spondylopathies
0.978 0.022 0.000
M20-M25 Other joint disorders
0.974 0.026 0.000
E10.4 With neurological complications
0.969 0.031 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.969 0.031 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.966 0.034 0.000
M45 Ankylosing spondylitis
0.965 0.035 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.964 0.036 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.963 0.037 0.000
S68 Traumatic amputation of wrist and hand
0.959 0.041 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.953 0.047 0.000
M86-M90 Other osteopathies
0.953 0.047 0.000
E10.5 With peripheral circulatory complications
0.949 0.051 0.000
J09-J18 Influenza and pneumonia
0.949 0.051 0.000
S61 Open wound of wrist and hand
0.932 0.068 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.930 0.069 0.000
J20-J22 Other acute lower respiratory infections
0.930 0.070 0.000
M75.2 Bicipital tendinitis
0.926 0.074 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.924 0.076 0.000
J81 Pulmonary oedema
0.915 0.085 0.000
M25 Other joint disorders, not elsewhere classified
0.915 0.085 0.000
T43.2 Other and unspecified antidepressants
0.911 0.089 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.910 0.090 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.905 0.095 0.000
H20 Iridocyclitis
0.904 0.096 0.000
M86 Osteomyelitis
0.902 0.098 0.000
M48 Other spondylopathies
0.902 0.098 0.000
J95-J99 Other diseases of the respiratory system
0.897 0.103 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.893 0.107 0.000
M35 Other systemic involvement of connective tissue
0.890 0.110 0.000
J22 Unspecified acute lower respiratory infection
0.889 0.111 0.000
M91-M94 Chondropathies
0.889 0.111 0.000
E10.8 With unspecified complications
0.889 0.111 0.000
M21 Other acquired deformities of limbs
0.884 0.116 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.883 0.116 0.000
M24 Other specific joint derangements
0.882 0.118 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.876 0.124 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.874 0.126 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.863 0.137 0.000
S70-S79 Injuries to the hip and thigh
0.862 0.138 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.860 0.140 0.000
M86.9 Osteomyelitis, unspecified
0.860 0.140 0.000
H18 Other disorders of cornea
0.856 0.144 0.000
M48.0 Spinal stenosis
0.854 0.146 0.000
L20-L30 Dermatitis and eczema
0.853 0.147 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.847 0.153 0.000
S61.8 Open wound of other parts of wrist and hand
0.846 0.154 0.000
T51 Toxic effect of alcohol
0.845 0.155 0.000
E10.2 With renal complications
0.844 0.156 0.000
L30 Other dermatitis
0.844 0.156 0.000
M05-M14 Inflammatory polyarthropathies
0.843 0.157 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.842 0.158 0.000
J98 Other respiratory disorders
0.841 0.159 0.000
E16 Other disorders of pancreatic internal secretion
0.839 0.161 0.000
J18 Pneumonia, organism unspecified
0.837 0.163 0.000
L30.9 Dermatitis, unspecified
0.835 0.165 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.834 0.166 0.000
M35.3 Polymyalgia rheumatica
0.830 0.170 0.000
H20.9 Iridocyclitis, unspecified
0.830 0.170 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.829 0.171 0.000
M75.5 Bursitis of shoulder
0.829 0.171 0.000
J98.1 Pulmonary collapse
0.826 0.174 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.823 0.177 0.000
M21.1 Varus deformity, not elsewhere classified
0.821 0.179 0.000
M48.06 Spinal stenosis (Lumbar region)
0.820 0.180 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.818 0.182 0.000
M25.5 Pain in joint
0.817 0.183 0.000
M60-M63 Disorders of muscles
0.814 0.186 0.000
Chapter V Mental and behavioural disorders
0.812 0.188 0.000
S62 Fracture at wrist and hand level
0.810 0.190 0.000
M75.9 Shoulder lesion, unspecified
0.810 0.190 0.000
E40-E46 Malnutrition
0.808 0.192 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.808 0.192 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.808 0.192 0.000
Q50-Q56 Congenital malformations of genital organs
0.803 0.197 0.000
S10-S19 Injuries to the neck
0.802 0.198 0.000
M25.51 Pain in joint (Shoulder region)
0.799 0.201 0.000
E10.6 With other specified complications
0.797 0.203 0.000
J84 Other interstitial pulmonary diseases
0.797 0.203 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.796 0.204 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.795 0.205 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.794 0.206 0.000
M94 Other disorders of cartilage
0.792 0.208 0.000
T51.0 Ethanol
0.792 0.208 0.000
M75.3 Calcific tendinitis of shoulder
0.791 0.209 0.000
S68.0 Traumatic amputation of thumb (complete)(partial)
0.790 0.210 0.000
E16.2 Hypoglycaemia, unspecified
0.785 0.215 0.000
H34 Retinal vascular occlusions
0.785 0.215 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.785 0.215 0.000
J90-J94 Other diseases of pleura
0.784 0.216 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.783 0.217 0.000
M90 Osteopathies in diseases classified elsewhere
0.783 0.217 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.782 0.218 0.000
M06 Other rheumatoid arthritis
0.778 0.222 0.000
M75.0 Adhesive capsulitis of shoulder
0.777 0.223 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.775 0.225 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.227 0.000
M00-M03 Infectious arthropathies
0.772 0.228 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.772 0.228 0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.771 0.229 0.000
J17 Pneumonia in diseases classified elsewhere
0.770 0.229 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.766 0.234 0.000
J15.4 Pneumonia due to other streptococci
0.765 0.235 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.763 0.237 0.000
S65 Injury of blood vessels at wrist and hand level
0.761 0.238 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.761 0.239 0.000
H10-H13 Disorders of conjunctiva
0.758 0.242 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.756 0.244 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.753 0.247 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.752 0.247 0.000
M72 Fibroblastic disorders
0.752 0.248 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.750 0.250 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.750 0.250 0.000
Q23 Congenital malformations of aortic and mitral valves
0.749 0.251 0.000
E14 Unspecified diabetes mellitus
0.749 0.251 0.000
H31 Other disorders of choroid
0.748 0.252 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.747 0.252 0.000
M32 Systemic lupus erythematosus
0.746 0.254 0.000
M24.1 Other articular cartilage disorders
0.746 0.254 0.000
F41 Other anxiety disorders
0.745 0.255 0.000
M65-M68 Disorders of synovium and tendon
0.743 0.257 0.000
L28 Lichen simplex chronicus and prurigo
0.743 0.257 0.000
T59 Toxic effect of other gases, fumes and vapours
0.742 0.258 0.000
S20-S29 Injuries to the thorax
0.740 0.260 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.738 0.262 0.000
J14 Pneumonia due to Haemophilus influenzae
0.737 0.263 0.000
M33 Dermatopolymyositis
0.736 0.264 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.734 0.266 0.000
H21 Other disorders of iris and ciliary body
0.734 0.266 0.000
S79 Other and unspecified injuries of hip and thigh
0.732 0.268 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.732 0.268 0.000
T65 Toxic effect of other and unspecified substances
0.730 0.270 0.000
Q60-Q64 Congenital malformations of the urinary system
0.729 0.271 0.000
M06.9 Rheumatoid arthritis, unspecified
0.727 0.273 0.000
J85 Abscess of lung and mediastinum
0.725 0.275 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.723 0.276 0.000
M94.8 Other specified disorders of cartilage
0.723 0.277 0.000
H18.4 Corneal degeneration
0.723 0.277 0.000
M24.2 Disorder of ligament
0.722 0.278 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M25.4 Effusion of joint
0.717 0.283 0.000
M75.8 Other shoulder lesions
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
S61.0 Open wound of finger(s) without damage to nail
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
M25.59 Pain in joint (Site unspecified)
0.713 0.287 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.713 0.287 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.713 0.287 0.000
H30 Chorioretinal inflammation
0.713 0.287 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.712 0.287 0.000
H17 Corneal scars and opacities
0.712 0.287 0.000
H20.0 Acute and subacute iridocyclitis
0.712 0.288 0.000
M40-M43 Deforming dorsopathies
0.711 0.289 0.000
M70.4 Prepatellar bursitis
0.710 0.290 0.000
M25.7 Osteophyte
0.710 0.290 0.000
T39.0 Salicylates
0.710 0.290 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.709 0.290 0.000
S69 Other and unspecified injuries of wrist and hand
0.709 0.291 0.000
F42 Obsessive-compulsive disorder
0.708 0.292 0.000
Q80-Q89 Other congenital malformations
0.708 0.292 0.000
S70 Superficial injury of hip and thigh
0.707 0.293 0.000
Chapter XXII Codes for special purposes
0.706 0.294 0.000
H53-H54 Visual disturbances and blindness
0.705 0.295 0.000
M70.2 Olecranon bursitis
0.702 0.298 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.702 0.298 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.702 0.298 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.702 0.298 0.000
M49 Spondylopathies in diseases classified elsewhere
0.701 0.299 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.699 0.301 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.698 0.302 0.000
M30 Polyarteritis nodosa and related conditions
0.698 0.302 0.000
M89 Other disorders of bone
0.698 0.302 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.698 0.302 0.000
F41.9 Anxiety disorder, unspecified
0.698 0.302 0.000
J18.1 Lobar pneumonia, unspecified
0.697 0.303 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.696 0.304 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.695 0.305 0.000
H15 Disorders of sclera
0.695 0.305 0.000
M22 Disorders of patella
0.693 0.307 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.692 0.308 0.000
Q35-Q37 Cleft lip and cleft palate
0.692 0.308 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.692 0.308 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.692 0.308 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.692 0.308 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.692 0.308 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.692 0.308 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.692 0.308 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.692 0.308 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.692 0.308 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.692 0.308 0.000
J18.0 Bronchopneumonia, unspecified
0.691 0.309 0.000
H18.6 Keratoconus
0.691 0.309 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.691 0.309 0.000
S67 Crushing injury of wrist and hand
0.691 0.309 0.000
T43.9 Psychotropic drug, unspecified
0.690 0.310 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.690 0.310 0.000
T43.6 Psychostimulants with abuse potential
0.690 0.310 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.690 0.310 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.690 0.310 0.000
H20.8 Other iridocyclitis
0.688 0.312 0.000
J11 Influenza, virus not identified
0.688 0.312 0.000
L10-L14 Bullous disorders
0.688 0.312 0.000
M71 Other bursopathies
0.688 0.312 0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified
0.688 0.312 0.000
S68.8 Traumatic amputation of other parts of wrist and hand
0.688 0.312 0.000
S68.4 Traumatic amputation of hand at wrist level
0.688 0.312 0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
0.688 0.312 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.687 0.313 0.000
J80 Adult respiratory distress syndrome
0.687 0.313 0.000
M86.6 Other chronic osteomyelitis
0.686 0.314 0.000
S64 Injury of nerves at wrist and hand level
0.684 0.316 0.000
J15.2 Pneumonia due to staphylococcus
0.684 0.316 0.000
M88 Paget's disease of bone [osteitis deformans]
0.684 0.316 0.000
M24.5 Contracture of joint
0.683 0.317 0.000
M76 Enthesopathies of lower limb, excluding foot
0.682 0.318 0.000
M07 Psoriatic and enteropathic arthropathies
0.682 0.318 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.681 0.319 0.000
E13 Other specified diabetes mellitus
0.681 0.319 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.680 0.319 0.000
J12 Viral pneumonia, not elsewhere classified
0.680 0.319 0.000
J09 Influenza due to certain identified influenza virus
0.680 0.319 0.000
Q23.1 Congenital insufficiency of aortic valve
0.680 0.320 0.000
M62 Other disorders of muscle
0.680 0.320 0.000
H16 Keratitis
0.679 0.321 0.000
M25.0 Haemarthrosis
0.677 0.323 0.000
H43-H45 Disorders of vitreous body and globe
0.676 0.324 0.000
L30.8 Other specified dermatitis
0.674 0.326 0.000
Q00-Q07 Congenital malformations of the nervous system
0.673 0.327 0.000
E46 Unspecified protein-energy malnutrition
0.672 0.328 0.000
M92 Other juvenile osteochondrosis
0.672 0.328 0.000
Chapter XX External causes of morbidity and mortality
0.670 0.330 0.000
M25.3 Other instability of joint
0.669 0.330 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.668 0.331 0.000
F41.2 Mixed anxiety and depressive disorder
0.668 0.332 0.000
T62 Toxic effect of other noxious substances eaten as food
0.667 0.333 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.667 0.333 0.000
T60 Toxic effect of pesticides
0.667 0.333 0.000
T57 Toxic effect of other inorganic substances
0.667 0.333 0.000
T56 Toxic effect of metals
0.667 0.333 0.000
T54 Toxic effect of corrosive substances
0.667 0.333 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.667 0.333 0.000
T52 Toxic effect of organic solvents
0.667 0.333 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.667 0.333 0.000
T58 Toxic effect of carbon monoxide
0.667 0.333 0.000
T55 Toxic effect of soaps and detergents
0.667 0.333 0.000
M21.2 Flexion deformity
0.667 0.333 0.000
J21 Acute bronchiolitis
0.667 0.333 0.000
H18.2 Other corneal oedema
0.667 0.333 0.000
S61.7 Multiple open wounds of wrist and hand
0.665 0.335 0.000
M11 Other crystal arthropathies
0.664 0.336 0.000
L28.0 Lichen simplex chronicus
0.664 0.336 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.663 0.337 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.663 0.337 0.000
S62.6 Fracture of other finger
0.662 0.338 0.000
J94 Other pleural conditions
0.662 0.338 0.000
M90.7 Fracture of bone in neoplastic disease
0.661 0.339 0.000
T40.4 Other synthetic narcotics
0.661 0.339 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.661 0.339 0.000
T79-T79 Certain early complications of trauma
0.660 0.339 0.000
F40 Phobic anxiety disorders
0.660 0.339 0.000
H34.2 Other retinal artery occlusions
0.658 0.342 0.000
H18.8 Other specified disorders of cornea
0.657 0.343 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.657 0.343 0.000
M50-M54 Other dorsopathies
0.657 0.343 0.000
M25.2 Flail joint
0.656 0.344 0.000
M25.1 Fistula of joint
0.656 0.344 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.656 0.344 0.000
M48.02 Spinal stenosis (Cervical region)
0.656 0.344 0.000
M21.6 Other acquired deformities of ankle and foot
0.655 0.345 0.000
E50-E64 Other nutritional deficiencies
0.655 0.345 0.000
H52 Disorders of refraction and accommodation
0.655 0.345 0.000
M35.0 Sicca syndrome [Sjogren]
0.654 0.346 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.652 0.348 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.652 0.348 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.652 0.348 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.652 0.348 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.652 0.348 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.652 0.348 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.652 0.348 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.652 0.348 0.000
T44.0 Anticholinesterase agents
0.652 0.348 0.000
T63 Toxic effect of contact with venomous animals
0.652 0.348 0.000
M87 Osteonecrosis
0.652 0.348 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.651 0.349 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.651 0.349 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.650 0.350 0.000
M24.0 Loose body in joint
0.649 0.350 0.000
M93 Other osteochondropathies
0.649 0.351 0.000
E15 Nondiabetic hypoglycaemic coma
0.649 0.351 0.000
L21 Seborrhoeic dermatitis
0.649 0.351 0.000
H20.2 Lens-induced iridocyclitis
0.648 0.352 0.000
H20.1 Chronic iridocyclitis
0.648 0.352 0.000
J85.2 Abscess of lung without pneumonia
0.647 0.352 0.000
F17.2 Dependence syndrome
0.647 0.353 0.000
M86.8 Other osteomyelitis
0.647 0.353 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.647 0.353 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.647 0.353 0.000
M86.3 Chronic multifocal osteomyelitis
0.647 0.353 0.000
M86.2 Subacute osteomyelitis
0.647 0.353 0.000
M86.1 Other acute osteomyelitis
0.647 0.353 0.000
M86.0 Acute haematogenous osteomyelitis
0.647 0.353 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.647 0.353 0.000
M48.9 Spondylopathy, unspecified
0.647 0.353 0.000
M48.8 Other specified spondylopathies
0.647 0.353 0.000
M48.4 Fatigue fracture of vertebra
0.647 0.353 0.000
M48.3 Traumatic spondylopathy
0.647 0.353 0.000
M48.2 Kissing spine
0.647 0.353 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.647 0.353 0.000
M25.9 Joint disorder, unspecified
0.644 0.355 0.000
J96 Respiratory failure, not elsewhere classified
0.643 0.357 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.642 0.358 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.642 0.358 0.000
S79.9 Unspecified injury of hip and thigh
0.639 0.361 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.638 0.362 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.638 0.362 0.000
M35.8 Other specified systemic involvement of connective tissue
0.638 0.362 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.638 0.362 0.000
M35.5 Multifocal fibrosclerosis
0.638 0.362 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.638 0.362 0.000
M35.2 Behcet's disease
0.638 0.362 0.000
M35.1 Other overlap syndromes
0.638 0.362 0.000
M14 Arthropathies in other diseases classified elsewhere
0.638 0.362 0.000
T40.6 Other and unspecified narcotics
0.638 0.362 0.000
S62.1 Fracture of other carpal bone(s)
0.637 0.362 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.637 0.362 0.000
J10 Influenza due to identified influenza virus
0.637 0.363 0.000
M21.9 Acquired deformity of limb, unspecified
0.634 0.366 0.000
M21.8 Other specified acquired deformities of limbs
0.634 0.366 0.000
M21.7 Unequal limb length (acquired)
0.634 0.366 0.000
M21.4 Flat foot [pes planus] (acquired)
0.634 0.366 0.000
H18.9 Disorder of cornea, unspecified
0.634 0.366 0.000
M34 Systemic sclerosis
0.633 0.367 0.000
J60-J70 Lung diseases due to external agents
0.633 0.367 0.000
M24.9 Joint derangement, unspecified
0.632 0.367 0.000
M24.7 Protrusio acetabuli
0.632 0.367 0.000
M24.6 Ankylosis of joint
0.632 0.367 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.632 0.367 0.000
H34.9 Retinal vascular occlusion, unspecified
0.632 0.368 0.000
L50-L54 Urticaria and erythema
0.632 0.368 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.631 0.369 0.000
Q17 Other congenital malformations of ear
0.628 0.372 0.000
T45.5 Anticoagulants
0.628 0.372 0.000
J17.3 Pneumonia in parasitic diseases
0.627 0.373 0.000
J15.9 Bacterial pneumonia, unspecified
0.626 0.374 0.000
J15.8 Other bacterial pneumonia
0.626 0.374 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.626 0.374 0.000
J15.5 Pneumonia due to Escherichia coli
0.626 0.374 0.000
J15.3 Pneumonia due to streptococcus, group B
0.626 0.374 0.000
M25.72 Osteophyte (Upper arm)
0.626 0.374 0.000
S50-S59 Injuries to the elbow and forearm
0.625 0.375 0.000
S14 Injury of nerves and spinal cord at neck level
0.625 0.375 0.000
H49 Paralytic strabismus
0.624 0.376 0.000
E14.8 With unspecified complications
0.622 0.378 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.622 0.378 0.000
M66 Spontaneous rupture of synovium and tendon
0.622 0.378 0.000
Q12 Congenital lens malformations
0.622 0.378 0.000
Q53 Undescended testicle
0.622 0.378 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.621 0.379 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.620 0.380 0.000
J93 Pneumothorax
0.619 0.381 0.000
M35.7 Hypermobility syndrome
0.619 0.381 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.618 0.381 0.000
T39.4 Antirheumatics, not elsewhere classified
0.618 0.381 0.000
T39.2 Pyrazolone derivatives
0.618 0.381 0.000
S78 Traumatic amputation of hip and thigh
0.618 0.382 0.000
S77 Crushing injury of hip and thigh
0.618 0.382 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.618 0.382 0.000
S75 Injury of blood vessels at hip and thigh level
0.618 0.382 0.000
S74 Injury of nerves at hip and thigh level
0.618 0.382 0.000
J20 Acute bronchitis
0.618 0.382 0.000
S62.3 Fracture of other metacarpal bone
0.617 0.383 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.616 0.383 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.616 0.383 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.616 0.383 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.616 0.383 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.616 0.383 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.616 0.383 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.616 0.383 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.616 0.383 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.616 0.383 0.000
M06.4 Inflammatory polyarthropathy
0.616 0.384 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.616 0.384 0.000
S40-S49 Injuries to the shoulder and upper arm
0.616 0.384 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.616 0.384 0.000
H54 Blindness and low vision
0.615 0.385 0.000
J18.9 Pneumonia, unspecified
0.615 0.385 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.615 0.385 0.000
H18.7 Other corneal deformities
0.614 0.386 0.000
H18.3 Changes in corneal membranes
0.614 0.386 0.000
H18.1 Bullous keratopathy
0.614 0.386 0.000
H18.0 Corneal pigmentations and deposits
0.614 0.386 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.614 0.386 0.000
L29 Pruritus
0.614 0.386 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.613 0.387 0.000
Q39 Congenital malformations of oesophagus
0.612 0.388 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.612 0.388 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.612 0.388 0.000
M48.04 Spinal stenosis (Thoracic region)
0.612 0.388 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.612 0.388 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.612 0.388 0.000
F43 Reaction to severe stress, and adjustment disorders
0.612 0.388 0.000
L25 Unspecified contact dermatitis
0.611 0.389 0.000
L24 Irritant contact dermatitis
0.611 0.389 0.000
L23 Allergic contact dermatitis
0.611 0.389 0.000
L20 Atopic dermatitis
0.611 0.389 0.000
L26 Exfoliative dermatitis
0.611 0.389 0.000
L22 Diaper [napkin] dermatitis
0.611 0.389 0.000
S60 Superficial injury of wrist and hand
0.610 0.390 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.610 0.390 0.000
M25.54 Pain in joint (Hand)
0.609 0.391 0.000
M00 Pyogenic arthritis
0.609 0.391 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.608 0.392 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.608 0.392 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.607 0.392 0.000
Q66 Congenital deformities of feet
0.607 0.393 0.000
M21.3 Wrist or foot drop (acquired)
0.607 0.393 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.607 0.393 0.000
T59.8 Other specified gases, fumes and vapours
0.607 0.393 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.606 0.393 0.000
T51.8 Other alcohols
0.606 0.394 0.000
T51.3 Fusel oil
0.606 0.394 0.000
T51.2 2-Propanol
0.606 0.394 0.000
T51.1 Methanol
0.606 0.394 0.000
L30.5 Pityriasis alba
0.605 0.395 0.000
L30.4 Erythema intertrigo
0.605 0.395 0.000
L30.3 Infective dermatitis
0.605 0.395 0.000
L30.2 Cutaneous autosensitisation
0.605 0.395 0.000
L30.1 Dyshidrosis [pompholyx]
0.605 0.395 0.000
L30.0 Nummular dermatitis
0.605 0.395 0.000
M12 Other specific arthropathies
0.605 0.395 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.605 0.395 0.000
M08 Juvenile arthritis
0.605 0.395 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.604 0.396 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.604 0.396 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.604 0.396 0.000
M70.7 Other bursitis of hip
0.604 0.396 0.000
M70.5 Other bursitis of knee
0.604 0.396 0.000
M70.3 Other bursitis of elbow
0.604 0.396 0.000
M70.1 Bursitis of hand
0.604 0.396 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.604 0.396 0.000
J98.6 Disorders of diaphragm
0.603 0.397 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.603 0.397 0.000
J98.3 Compensatory emphysema
0.603 0.397 0.000
J98.2 Interstitial emphysema
0.603 0.397 0.000
H33 Retinal detachments and breaks
0.603 0.397 0.000
M70.22 Olecranon bursitis-Upper arm
0.602 0.398 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.602 0.398 0.000
S31 Open wound of abdomen, lower back and pelvis
0.602 0.398 0.000
E20-E35 Disorders of other endocrine glands
0.602 0.398 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.602 0.398 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.602 0.398 0.000
E16.4 Abnormal secretion of gastrin
0.602 0.398 0.000
E16.3 Increased secretion of glucagon
0.602 0.398 0.000
E16.1 Other hypoglycaemia
0.602 0.398 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.600 0.399 0.000
M80-M85 Disorders of bone density and structure
0.600 0.400 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.600 0.400 0.000
J18.8 Other pneumonia, organism unspecified
0.600 0.400 0.000
J18.2 Hypostatic pneumonia, unspecified
0.600 0.400 0.000
Q23.0 Congenital stenosis of aortic valve
0.598 0.402 0.000
S12 Fracture of neck
0.597 0.402 0.000
M25.8 Other specified joint disorders
0.597 0.403 0.000
Chapter VI Diseases of the nervous system
0.597 0.403 0.000
J90 Pleural effusion, not elsewhere classified
0.597 0.403 0.000
S69.8 Other specified injuries of wrist and hand
0.596 0.404 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.595 0.405 0.000
S65.0 Injury of ulnar artery at wrist and hand level
0.595 0.405 0.000
E14.3 With ophthalmic complications
0.595 0.405 0.000
S62.4 Multiple fractures of metacarpal bones
0.594 0.406 0.000
T42.1 Iminostilbenes
0.593 0.406 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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