TreeWAS – Variant ID: rs10489764

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.850	0.150
Z95.3 Presence of xenogenic heart valve	0.000	0.855	0.145
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.858	0.142
Z95.4 Presence of other heart-valve replacement	0.000	0.860	0.140
Z95.1 Presence of aortocoronary bypass graft	0.000	0.861	0.139
Z95.2 Presence of prosthetic heart valve	0.000	0.867	0.133
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.874	0.126
Z95.0 Presence of cardiac pacemaker	0.000	0.877	0.123
H71 Cholesteatoma of middle ear	0.000	0.920	0.080
H65-H75 Diseases of middle ear and mastoid	0.000	0.925	0.075
H74 Other disorders of middle ear and mastoid	0.000	0.930	0.070
H73 Other disorders of tympanic membrane	0.000	0.930	0.070
H73.8 Other specified disorders of tympanic membrane	0.000	0.932	0.068
Chapter VIII Diseases of the ear and mastoid process	0.000	0.937	0.063
H90-H95 Other disorders of ear	0.000	0.937	0.063
H74.1 Adhesive middle ear disease	0.000	0.938	0.062
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.940	0.060
H92.0 Otalgia	0.000	0.940	0.060
H92 Otalgia and effusion of ear	0.000	0.941	0.059
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.941	0.059
H90 Conductive and sensorineural hearing loss	0.000	0.941	0.059
H66 Suppurative and unspecified otitis media	0.000	0.943	0.057
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.946	0.054
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.946	0.054
H67 Otitis media in diseases classified elsewhere	0.000	0.946	0.054
H68 Eustachian salpingitis and obstruction	0.000	0.947	0.053
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.947	0.053
H80-H83 Diseases of inner ear	0.000	0.947	0.053
H90.2 Conductive hearing loss, unspecified	0.000	0.949	0.051
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.949	0.051
H74.0 Tympanosclerosis	0.000	0.950	0.050
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.950	0.050
H73.1 Chronic myringitis	0.000	0.950	0.050
H73.0 Acute myringitis	0.000	0.950	0.050
H74.4 Polyp of middle ear	0.000	0.951	0.049
H80 Otosclerosis	0.000	0.952	0.048
H72 Perforation of tympanic membrane	0.000	0.952	0.048
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.952	0.048
H69 Other disorders of Eustachian tube	0.000	0.953	0.047
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.953	0.047
H70 Mastoiditis and related conditions	0.000	0.953	0.046
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.954	0.046
E55.9 Vitamin D deficiency, unspecified	0.046	0.954	0.000
H91 Other hearing loss	0.000	0.955	0.045
H80.9 Otosclerosis, unspecified	0.000	0.955	0.045
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.955	0.045
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.956	0.044
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.956	0.044
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.956	0.043
H95.1 Other disorders following mastoidectomy	0.000	0.957	0.043
H92.2 Otorrhagia	0.000	0.957	0.042
H90.5 Sensorineural hearing loss, unspecified	0.000	0.957	0.043
H66.3 Other chronic suppurative otitis media	0.000	0.958	0.042
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.959	0.041
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.959	0.041
H66.0 Acute suppurative otitis media	0.000	0.959	0.041
H72.0 Central perforation of tympanic membrane	0.000	0.960	0.040
H81 Disorders of vestibular function	0.000	0.960	0.040
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.961	0.039
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.961	0.039
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.961	0.039
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.961	0.039
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.961	0.039
H68.0 Eustachian salpingitis	0.000	0.962	0.038
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.962	0.038
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.962	0.038
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.962	0.038
H68.1 Obstruction of Eustachian tube	0.000	0.963	0.037
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.963	0.037
H91.3 Deaf mutism, not elsewhere classified	0.000	0.963	0.037
H81.0 Meniere's disease	0.000	0.963	0.037
H66.9 Otitis media, unspecified	0.000	0.964	0.036
H90.0 Conductive hearing loss, bilateral	0.000	0.964	0.036
H91.9 Hearing loss, unspecified	0.000	0.965	0.035
H70.8 Other mastoiditis and related conditions	0.000	0.965	0.035
H80.8 Other otosclerosis	0.000	0.965	0.035
H80.2 Cochlear otosclerosis	0.000	0.965	0.035
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.965	0.035
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.965	0.035
H72.1 Attic perforation of tympanic membrane	0.000	0.966	0.034
H69.0 Patulous Eustachian tube	0.000	0.966	0.034
H66.4 Suppurative otitis media, unspecified	0.000	0.966	0.034
H70.2 Petrositis	0.000	0.966	0.033
H72.2 Other marginal perforations of tympanic membrane	0.000	0.966	0.034
H81.2 Vestibular neuronitis	0.000	0.967	0.033
H72.8 Other perforations of tympanic membrane	0.000	0.967	0.033
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.967	0.032
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.967	0.032
H90.3 Sensorineural hearing loss, bilateral	0.000	0.967	0.032
H70.1 Chronic mastoiditis	0.000	0.968	0.032
H91.0 Ototoxic hearing loss	0.000	0.968	0.032
H91.8 Other specified hearing loss	0.000	0.968	0.032
H69.8 Other specified disorders of Eustachian tube	0.000	0.968	0.032
H70.9 Mastoiditis, unspecified	0.000	0.969	0.031
H69.9 Eustachian tube disorder, unspecified	0.000	0.969	0.031
H91.2 Sudden idiopathic hearing loss	0.000	0.970	0.030
H70.0 Acute mastoiditis	0.000	0.970	0.030
H81.4 Vertigo of central origin	0.000	0.971	0.029
H83 Other diseases of inner ear	0.000	0.973	0.027
H91.1 Presbycusis	0.000	0.973	0.027
H81.3 Other peripheral vertigo	0.000	0.974	0.026
H81.8 Other disorders of vestibular function	0.000	0.975	0.025
H81.9 Disorder of vestibular function, unspecified	0.000	0.975	0.025
H93 Other disorders of ear, not elsewhere classified	0.000	0.976	0.024
E55 Vitamin D deficiency	0.023	0.977	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.978	0.022
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.978	0.021
H60-H62 Diseases of external ear	0.000	0.980	0.020
H92.1 Otorrhoea	0.000	0.980	0.020
H83.3 Noise effects on inner ear	0.000	0.980	0.020
H93.9 Disorder of ear, unspecified	0.000	0.980	0.020
H83.2 Labyrinthine dysfunction	0.000	0.980	0.020
H83.1 Labyrinthine fistula	0.000	0.980	0.020
H93.0 Degenerative and vascular disorders of ear	0.000	0.982	0.017
E55.0 Rickets, active	0.016	0.983	0.000
H83.8 Other specified diseases of inner ear	0.000	0.984	0.016
H93.3 Disorders of acoustic nerve	0.000	0.984	0.016
H93.2 Other abnormal auditory perceptions	0.000	0.984	0.016
H81.1 Benign paroxysmal vertigo	0.000	0.984	0.016
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.985	0.015
I35.1 Aortic (valve) insufficiency	0.000	0.986	0.014
H65 Nonsuppurative otitis media	0.000	0.986	0.014
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.986	0.013
N89.6 Tight hymenal ring	0.000	0.987	0.013
M84.03 Malunion of fracture (Forearm)	0.013	0.987	0.000
N89 Other noninflammatory disorders of vagina	0.000	0.988	0.012
H93.8 Other specified disorders of ear	0.000	0.988	0.012
H61 Other disorders of external ear	0.000	0.990	0.010
H65.2 Chronic serous otitis media	0.000	0.990	0.010
H65.0 Acute serous otitis media	0.000	0.990	0.010
Z42.0 Follow-up care involving plastic surgery of head and neck	0.010	0.990	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.990	0.010
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.990	0.010
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.990	0.010
H62.2 Otitis externa in mycoses	0.000	0.990	0.010
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.990	0.010
M84.0 Malunion of fracture	0.010	0.990	0.000
N89.5 Stricture and atresia of vagina	0.000	0.990	0.010
H65.1 Other acute nonsuppurative otitis media	0.000	0.990	0.009
M84 Disorders of continuity of bone	0.009	0.991	0.000
H93.1 Tinnitus	0.000	0.991	0.009
N89.7 Haematocolpos	0.000	0.991	0.009
N89.4 Leukoplakia of vagina	0.000	0.991	0.009
N89.3 Dysplasia of vagina, unspecified	0.000	0.991	0.009
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.000	0.991	0.009
N89.1 Moderate vaginal dysplasia	0.000	0.991	0.009
H83.0 Labyrinthitis	0.000	0.991	0.009
N89.0 Mild vaginal dysplasia	0.000	0.991	0.009
M84.1 Nonunion of fracture [pseudarthrosis]	0.009	0.991	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.009	0.991	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.991	0.008
Z29.1 Prophylactic immunotherapy	0.000	0.991	0.009
H61.1 Non-infective disorders of pinna	0.000	0.991	0.008
H65.4 Other chronic nonsuppurative otitis media	0.000	0.992	0.008
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.008	0.992	0.000
N97.1 Female infertility of tubal origin	0.008	0.992	0.000
M84.2 Delayed union of fracture	0.008	0.992	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.008	0.992	0.000
M84.04 Malunion of fracture (Hand)	0.008	0.992	0.000
N97.9 Female infertility, unspecified	0.008	0.992	0.000
M84.4 Pathological fracture, not elsewhere classified	0.008	0.992	0.000
M84.09 Malunion of fracture (Site unspecified)	0.007	0.993	0.000
M84.08 Malunion of fracture (Other)	0.007	0.993	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.007	0.993	0.000
M84.00 Malunion of fracture (Multiple sites)	0.007	0.993	0.000
M84.8 Other disorders of continuity of bone	0.007	0.993	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.007	0.993	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.993	0.007
N97 Female infertility	0.007	0.993	0.000
M84.06 Malunion of fracture (Lower leg)	0.007	0.993	0.000
M84.02 Malunion of fracture (Upper arm)	0.007	0.993	0.000
H61.2 Impacted cerumen	0.000	0.993	0.007
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.007	0.993	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.993	0.007
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.993	0.007
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.007	0.993	0.000
M84.9 Disorder of continuity of bone, unspecified	0.007	0.993	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.007	0.993	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.007	0.993	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.006	0.993	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.006	0.993	0.000
H61.8 Other specified disorders of external ear	0.000	0.993	0.006
H60 Otitis externa	0.000	0.993	0.006
M84.3 Stress fracture, not elsewhere classified	0.006	0.994	0.000
N97.4 Female infertility associated with male factors	0.006	0.994	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.006	0.994	0.000
E50-E64 Other nutritional deficiencies	0.006	0.994	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.006	0.994	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.006	0.994	0.000
M84.28 Delayed union of fracture (Other)	0.006	0.994	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.006	0.994	0.000
M84.26 Delayed union of fracture (Lower leg)	0.006	0.994	0.000
M84.24 Delayed union of fracture (Hand)	0.006	0.994	0.000
M84.23 Delayed union of fracture (Forearm)	0.006	0.994	0.000
M84.22 Delayed union of fracture (Upper arm)	0.006	0.994	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.006	0.994	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.006	0.994	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.006	0.994	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.006	0.994	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.006	0.994	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.006	0.994	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.006	0.994	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.006	0.994	0.000
N80.1 Endometriosis of ovary	0.006	0.994	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.994	0.006
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.005	0.994	0.000
H61.0 Perichondritis of external ear	0.000	0.994	0.006
N97.0 Female infertility associated with anovulation	0.005	0.994	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.005	0.994	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.005	0.994	0.000
M84.88 Other disorders of continuity of bone (Other)	0.005	0.994	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.005	0.994	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.005	0.994	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.005	0.994	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.005	0.994	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.005	0.994	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.005	0.994	0.000
N97.8 Female infertility of other origin	0.005	0.994	0.000
I35 Nonrheumatic aortic valve disorders	0.000	0.994	0.006
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.005	0.994	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
N97.3 Female infertility of cervical origin	0.005	0.995	0.000
N97.2 Female infertility of uterine origin	0.005	0.995	0.000
M84.01 Malunion of fracture (Shoulder region)	0.005	0.995	0.000
H60.8 Other otitis externa	0.000	0.995	0.005
K63.2 Fistula of intestine	0.000	0.995	0.005
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.005	0.995	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.005	0.995	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.005	0.995	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.005	0.995	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.005	0.995	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.005	0.995	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.005	0.995	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.005	0.995	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.005	0.995	0.000
E04.9 Non-toxic goitre, unspecified	0.005	0.995	0.000
H60.2 Malignant otitis externa	0.000	0.995	0.005
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.995	0.005
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.005	0.995	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.005	0.995	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.005	0.995	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
H60.3 Other infective otitis externa	0.000	0.995	0.005
E64 Sequelae of malnutrition and other nutritional deficiencies	0.005	0.995	0.000
E63 Other nutritional deficiencies	0.005	0.995	0.000
E50 Vitamin A deficiency	0.005	0.995	0.000
E60 Dietary zinc deficiency	0.005	0.995	0.000
E59 Dietary selenium deficiency	0.005	0.995	0.000
E54 Ascorbic acid deficiency	0.005	0.995	0.000
E52 Niacin deficiency [pellagra]	0.005	0.995	0.000
H60.0 Abscess of external ear	0.000	0.995	0.004
E51 Thiamine deficiency	0.004	0.995	0.000
C25.0 Head of pancreas	0.005	0.995	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.995	0.004
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.000	0.996	0.004
E53 Deficiency of other B group vitamins	0.004	0.996	0.000
E56 Other vitamin deficiencies	0.004	0.996	0.000
E58 Dietary calcium deficiency	0.004	0.996	0.000
K81.1 Chronic cholecystitis	0.000	0.996	0.004
E61 Deficiency of other nutrient elements	0.004	0.996	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.996	0.004
G43.9 Migraine, unspecified	0.004	0.996	0.000
E53.9 Vitamin B deficiency, unspecified	0.004	0.996	0.000
I27.9 Pulmonary heart disease, unspecified	0.004	0.996	0.000
Z29 Need for other prophylactic measures	0.000	0.996	0.004
C25.1 Body of pancreas	0.004	0.996	0.000
F45.8 Other somatoform disorders	0.004	0.996	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.996	0.003
E50.9 Vitamin A deficiency, unspecified	0.003	0.996	0.000
E50.8 Other manifestations of vitamin A deficiency	0.003	0.996	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.003	0.996	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.003	0.996	0.000
E50.5 Vitamin A deficiency with night blindness	0.003	0.996	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.003	0.996	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.003	0.996	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.003	0.996	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.003	0.996	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.003	0.996	0.000
E63.9 Nutritional deficiency, unspecified	0.003	0.996	0.000
E63.8 Other specified nutritional deficiencies	0.003	0.996	0.000
E63.1 Imbalance of constituents of food intake	0.003	0.996	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.003	0.996	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.003	0.996	0.000
E64.8 Sequelae of other nutritional deficiencies	0.003	0.996	0.000
E64.3 Sequelae of rickets	0.003	0.996	0.000
E64.2 Sequelae of vitamin C deficiency	0.003	0.996	0.000
E64.1 Sequelae of vitamin A deficiency	0.003	0.996	0.000
E64.0 Sequelae of protein-energy malnutrition	0.003	0.996	0.000
E51.9 Thiamine deficiency, unspecified	0.003	0.996	0.000
E51.8 Other manifestations of thiamine deficiency	0.003	0.996	0.000
E51.1 Beriberi	0.003	0.996	0.000
C25.9 Pancreas, unspecified	0.004	0.996	0.000
C25 Malignant neoplasm of pancreas	0.004	0.996	0.000
E51.2 Wernicke's encephalopathy	0.003	0.997	0.000
E53.1 Pyridoxine deficiency	0.003	0.997	0.000
E53.0 Riboflavin deficiency	0.003	0.997	0.000
H60.1 Cellulitis of external ear	0.000	0.997	0.003
Z29.2 Other prophylactic chemotherapy	0.000	0.997	0.003
E56.9 Vitamin deficiency, unspecified	0.003	0.997	0.000
E56.8 Deficiency of other vitamins	0.003	0.997	0.000
E56.0 Deficiency of vitamin E	0.003	0.997	0.000
C25.7 Other parts of pancreas	0.003	0.997	0.000
E61.9 Deficiency of nutrient element, unspecified	0.003	0.997	0.000
E61.8 Deficiency of other specified nutrient elements	0.003	0.997	0.000
E61.7 Deficiency of multiple nutrient elements	0.003	0.997	0.000
E61.6 Vanadium deficiency	0.003	0.997	0.000
E61.5 Molybdenum deficiency	0.003	0.997	0.000
E61.4 Chromium deficiency	0.003	0.997	0.000
E61.3 Manganese deficiency	0.003	0.997	0.000
E61.0 Copper deficiency	0.003	0.997	0.000
E61.2 Magnesium deficiency	0.003	0.997	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.001
E56.1 Deficiency of vitamin K	0.003	0.997	0.000
T90.5 Sequelae of intracranial injury	0.000	0.997	0.003
H60.9 Otitis externa, unspecified	0.000	0.997	0.003
Z29.9 Prophylactic measure, unspecified	0.000	0.997	0.003
M80-M85 Disorders of bone density and structure	0.003	0.997	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.003	0.997	0.000
G93.3 Postviral fatigue syndrome	0.000	0.997	0.003
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.003	0.997	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.997	0.003
E53.8 Deficiency of other specified B group vitamins	0.003	0.997	0.000
M82 Osteoporosis in diseases classified elsewhere	0.003	0.997	0.000
C25.4 Endocrine pancreas	0.003	0.997	0.000
E61.1 Iron deficiency	0.003	0.997	0.000
M82.1 Osteoporosis in endocrine disorders	0.003	0.997	0.000
M85.6 Other cyst of bone	0.003	0.997	0.000
T90.4 Sequelae of injury of eye and orbit	0.000	0.997	0.003
C25.3 Pancreatic duct	0.002	0.997	0.000
H65.3 Chronic mucoid otitis media	0.000	0.997	0.002
T90 Sequelae of injuries of head	0.000	0.997	0.003
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
D23.4 Skin of scalp and neck	0.000	0.998	0.002
Z97.8 Presence of other specified devices	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
M85.66 Other cyst of bone (Lower leg)	0.002	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.002	0.998	0.000
M83 Adult osteomalacia	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.000	0.998	0.002
I27 Other pulmonary heart diseases	0.002	0.998	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.002	0.998	0.000
Z29.0 Isolation	0.000	0.998	0.002
E23.7 Disorder of pituitary gland, unspecified	0.002	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.002	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.002	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.002	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.002	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.002	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.002	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.002	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.002	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.002	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.002	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.000	0.998	0.002
M85.69 Other cyst of bone (Site unspecified)	0.002	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.002	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.002	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.002	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.000	0.998	0.002
T90.1 Sequelae of open wound of head	0.000	0.998	0.002
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
M85.68 Other cyst of bone (Other)	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
F03 Unspecified dementia	0.002	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.002	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
T90.3 Sequelae of injury of cranial nerves	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.998	0.002
R47.8 Other and unspecified speech disturbances	0.000	0.998	0.002
C25.2 Tail of pancreas	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
M83.9 Adult osteomalacia, unspecified	0.002	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.998	0.000
M83.4 Aluminum bone disease	0.002	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.998	0.000
M83.0 Puerperal osteomalacia	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.000	0.998	0.002
M81 Osteoporosis without pathological fracture	0.002	0.998	0.000
R13 Dysphagia	0.000	0.998	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.998	0.002
M83.8 Other adult osteomalacia	0.002	0.998	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.002	0.998	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.002	0.998	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.002	0.998	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.002	0.998	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.002	0.998	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.002	0.998	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.002	0.998	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.002	0.998	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.002	0.998	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.002	0.998	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.002	0.998	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.002	0.998	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.002	0.998	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.002	0.998	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.002	0.998	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.002	0.998	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.002	0.998	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.002	0.998	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.002	0.998	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.002	0.998	0.000
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
M83.1 Senile osteomalacia	0.002	0.998	0.000
M85.2 Hyperostosis of skull	0.002	0.998	0.000
S05.1 Contusion of eyeball and orbital tissues	0.002	0.998	0.000
M85.46 Solitary bone cyst (Lower leg)	0.002	0.998	0.000
I27.8 Other specified pulmonary heart diseases	0.002	0.998	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.002	0.998	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
M81.0 Postmenopausal osteoporosis	0.002	0.998	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.002	0.998	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.002	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.002	0.998	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.002	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.002	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.002	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.002	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.002	0.998	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.002	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.002	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.002	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.002	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.002	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.002	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
M20.4 Other hammer toe(s) (acquired)	0.000	0.998	0.002
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.001	0.998	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.001	0.998	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.001	0.998	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.001	0.998	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.001	0.998	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.001	0.998	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.001	0.998	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.001	0.998	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.001	0.998	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.001	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.001	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.001	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.001	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.001	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.001	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.001	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.001	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.001	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.001	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.001	0.998	0.000
M85.38 Osteitis condensans (Other)	0.001	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.001	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.001	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.001	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.001	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.001	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.001	0.998	0.000
M85.31 Osteitis condensans (Shoulder region)	0.001	0.998	0.000
M85.30 Osteitis condensans (Multiple sites)	0.001	0.998	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.001	0.998	0.000
M85.58 Aneurysmal bone cyst (Other)	0.001	0.998	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.001	0.998	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.001	0.998	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.001	0.998	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.001	0.998	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations