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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1049110
log Bayes Factor = 125.97
Chromosome 6   position 32,726,803  (GRCh37) Explore rs1049110 on Ensembl!
Variant rs1049110 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
D50.9 Iron deficiency anaemia, unspecified
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
E14.9 Without complications
0.000 0.006 0.994
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.007 0.993
D50 Iron deficiency anaemia
0.000 0.008 0.992
E00-E07 Disorders of thyroid gland
0.000 0.008 0.992
D50-D53 Nutritional anaemias
0.000 0.009 0.991
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.011 0.989
G37 Other demyelinating diseases of central nervous system
0.000 0.013 0.987
D51 Vitamin B12 deficiency anaemia
0.000 0.014 0.986
E50-E64 Other nutritional deficiencies
0.000 0.020 0.980
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.022 0.978
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.026 0.974
E14.3 With ophthalmic complications
0.000 0.026 0.974
E10.2 With renal complications
0.000 0.031 0.969
D86 Sarcoidosis
0.000 0.041 0.959
D80-D89 Certain disorders involving the immune mechanism
0.000 0.042 0.958
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.045 0.955
D86.9 Sarcoidosis, unspecified
0.000 0.048 0.952
E20-E35 Disorders of other endocrine glands
0.000 0.054 0.946
E27 Other disorders of adrenal gland
0.000 0.056 0.944
E27.1 Primary adrenocortical insufficiency
0.000 0.062 0.938
E53 Deficiency of other B group vitamins
0.000 0.072 0.928
E55 Vitamin D deficiency
0.000 0.080 0.920
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.082 0.918
E10.4 With neurological complications
0.000 0.093 0.907
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.105 0.895
E10.5 With peripheral circulatory complications
0.000 0.105 0.895
E55.9 Vitamin D deficiency, unspecified
0.000 0.123 0.877
E53.8 Deficiency of other specified B group vitamins
0.000 0.125 0.875
D86.0 Sarcoidosis of lung
0.000 0.132 0.868
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.136 0.864
E05.9 Thyrotoxicosis, unspecified
0.000 0.150 0.850
D86.8 Sarcoidosis of other and combined sites
0.000 0.152 0.848
E14.6 With other specified complications
0.000 0.158 0.842
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.163 0.837
E27.2 Addisonian crisis
0.000 0.164 0.836
K90 Intestinal malabsorption
0.000 0.179 0.821
E14.8 With unspecified complications
0.000 0.181 0.819
E20 Hypoparathyroidism
0.000 0.190 0.810
E10.0 With coma
0.000 0.200 0.800
E40-E46 Malnutrition
0.000 0.209 0.791
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.216 0.784
E14.2 Withrenal complications
0.000 0.219 0.781
K90.9 Intestinal malabsorption, unspecified
0.000 0.221 0.779
E10.7 With multiple complications
0.000 0.233 0.767
D80 Immunodeficiency with predominantly antibody defects
0.000 0.234 0.766
D86.3 Sarcoidosis of skin
0.000 0.242 0.758
E14.5 With peripheral circulatory complications
0.000 0.246 0.754
E10.8 With unspecified complications
0.000 0.256 0.743
E53.9 Vitamin B deficiency, unspecified
0.000 0.257 0.743
E27.8 Other specified disorders of adrenal gland
0.000 0.257 0.743
E13 Other specified diabetes mellitus
0.000 0.258 0.742
E10.6 With other specified complications
0.000 0.265 0.735
E54 Ascorbic acid deficiency
0.000 0.267 0.733
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.270 0.730
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.272 0.728
E56 Other vitamin deficiencies
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E20.9 Hypoparathyroidism, unspecified
0.000 0.287 0.713
E05.5 Thyroid crisis or storm
0.000 0.288 0.712
E05.4 Thyrotoxicosis factitia
0.000 0.288 0.712
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.288 0.712
D50.1 Sideropenic dysphagia
0.000 0.289 0.711
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.289 0.711
E00 Congenital iodine-deficiency syndrome
0.000 0.289 0.711
G37.5 Concentric sclerosis [Balo]
0.000 0.292 0.708
G37.4 Subacute necrotising myelitis
0.000 0.292 0.708
G37.2 Central pontine myelinolysis
0.000 0.292 0.708
G37.1 Central demyelination of corpus callosum
0.000 0.292 0.708
G37.0 Diffuse sclerosis
0.000 0.292 0.708
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.293 0.707
D51.2 Transcobalamin II deficiency
0.000 0.293 0.707
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.293 0.707
D83 Common variable immunodeficiency
0.000 0.295 0.705
G36 Other acute disseminated demyelination
0.000 0.296 0.704
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.297 0.702
E63 Other nutritional deficiencies
0.000 0.297 0.702
E50 Vitamin A deficiency
0.000 0.297 0.702
E60 Dietary zinc deficiency
0.000 0.297 0.702
E59 Dietary selenium deficiency
0.000 0.297 0.702
E52 Niacin deficiency [pellagra]
0.000 0.297 0.702
D55-D59 Haemolytic anaemias
0.000 0.301 0.699
E24 Cushing's syndrome
0.000 0.303 0.697
E31 Polyglandular dysfunction
0.000 0.304 0.696
E14.0 With coma
0.000 0.307 0.693
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.311 0.689
E51 Thiamine deficiency
0.000 0.311 0.689
E27.9 Disorder of adrenal gland, unspecified
0.000 0.311 0.689
D86.1 Sarcoidosis of lymph nodes
0.000 0.313 0.687
D81 Combined immunodeficiencies
0.000 0.313 0.687
E07 Other disorders of thyroid
0.000 0.321 0.679
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.322 0.678
E32 Diseases of thymus
0.000 0.322 0.678
E30 Disorders of puberty, not elsewhere classified
0.000 0.322 0.678
E27.5 Adrenomedullary hyperfunction
0.000 0.323 0.677
E27.0 Other adrenocortical overactivity
0.000 0.323 0.677
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.326 0.673
E34 Other endocrine disorders
0.000 0.335 0.665
E53.1 Pyridoxine deficiency
0.000 0.335 0.665
E53.0 Riboflavin deficiency
0.000 0.335 0.665
E58 Dietary calcium deficiency
0.000 0.338 0.662
D84 Other immunodeficiencies
0.000 0.339 0.661
E55.0 Rickets, active
0.000 0.341 0.659
D82 Immunodeficiency associated with other major defects
0.000 0.344 0.655
D53 Other nutritional anaemias
0.000 0.345 0.655
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.355 0.645
E46 Unspecified protein-energy malnutrition
0.000 0.359 0.641
D50.8 Other iron deficiency anaemias
0.000 0.361 0.639
D59 Acquired haemolytic anaemia
0.000 0.370 0.630
E61 Deficiency of other nutrient elements
0.000 0.374 0.626
E14.1 With ketoacidosis
0.000 0.378 0.622
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.378 0.622
K90.8 Other intestinal malabsorption
0.000 0.380 0.620
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.380 0.620
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.390 0.610
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.391 0.609
E14.4 With neurological complications
0.000 0.394 0.606
E13.9 Without complications
0.000 0.397 0.603
D52 Folate deficiency anaemia
0.000 0.398 0.602
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.406 0.593
K90.3 Pancreatic steatorrhoea
0.000 0.411 0.589
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.411 0.589
K90.1 Tropical sprue
0.000 0.411 0.589
D59.1 Other autoimmune haemolytic anaemias
0.000 0.415 0.585
E20.8 Other hypoparathyroidism
0.000 0.419 0.581
E20.1 Pseudohypoparathyroidism
0.000 0.419 0.581
E20.0 Idiopathic hypoparathyroidism
0.000 0.419 0.581
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.421 0.579
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.422 0.578
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.423 0.577
E25 Adrenogenital disorders
0.000 0.431 0.569
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.433 0.567
E45 Retarded development following protein-energy malnutrition
0.000 0.433 0.567
E43 Unspecified severe protein-energy malnutrition
0.000 0.433 0.567
E42 Marasmic kwashiorkor
0.000 0.433 0.567
E41 Nutritional marasmus
0.000 0.433 0.567
E40 Kwashiorkor
0.000 0.433 0.567
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.433 0.566
D89.3 Immune reconstitution syndrome
0.000 0.438 0.562
E28 Ovarian dysfunction
0.000 0.440 0.560
E16.1 Other hypoglycaemia
0.000 0.441 0.558
M05.9 Seropositive rheumatoid arthritis, unspecified
0.552 0.448 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.451 0.549
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.451 0.549
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.451 0.549
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.451 0.549
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.451 0.549
E24.9 Cushing's syndrome, unspecified
0.000 0.455 0.545
E05.8 Other thyrotoxicosis
0.000 0.459 0.540
E24.0 Pituitary-dependent Cushing's disease
0.000 0.461 0.539
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.537 0.463 0.000
M05 Seropositive rheumatoid arthritis
0.533 0.467 0.000
M06 Other rheumatoid arthritis
0.533 0.467 0.000
E13.8 With unspecified complications
0.000 0.468 0.532
E13.7 With multiple complications
0.000 0.468 0.532
E13.6 With other specified complications
0.000 0.468 0.532
E13.5 With peripheral circulatory complications
0.000 0.468 0.532
E13.4 With neurological complications
0.000 0.468 0.532
E13.2 With renal complications
0.000 0.468 0.532
E13.1 With ketoacidosis
0.000 0.468 0.532
E13.0 With coma
0.000 0.468 0.532
E56.1 Deficiency of vitamin K
0.000 0.471 0.529
M06.9 Rheumatoid arthritis, unspecified
0.528 0.472 0.000
E34.0 Carcinoid syndrome
0.000 0.473 0.527
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.526 0.474 0.000
E24.8 Other Cushing's syndrome
0.000 0.476 0.524
D83.9 Common variable immunodeficiency, unspecified
0.000 0.476 0.523
D89.1 Cryoglobulinaemia
0.000 0.478 0.522
E22 Hyperfunction of pituitary gland
0.000 0.481 0.519
E31.0 Autoimmune polyglandular failure
0.000 0.483 0.517
M05-M14 Inflammatory polyarthropathies
0.516 0.484 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.485 0.515
E56.9 Vitamin deficiency, unspecified
0.000 0.486 0.514
E56.8 Deficiency of other vitamins
0.000 0.486 0.514
E56.0 Deficiency of vitamin E
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E26 Hyperaldosteronism
0.000 0.486 0.513
M06.3 Rheumatoid nodule
0.511 0.489 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.489 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.490 0.510
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.490 0.510
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.490 0.510
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.490 0.510
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.490 0.510
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.490 0.510
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.490 0.510
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.490 0.510
E34.8 Other specified endocrine disorders
0.000 0.491 0.509
D84.8 Other specified immunodeficiencies
0.000 0.492 0.508
E06 Thyroiditis
0.000 0.493 0.507
E07.9 Disorder of thyroid, unspecified
0.000 0.493 0.507
E23 Hypofunction and other disorders of pituitary gland
0.000 0.493 0.506
D83.8 Other common variable immunodeficiencies
0.000 0.494 0.505
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.494 0.505
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.494 0.505
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.494 0.505
G36.9 Acute disseminated demyelination, unspecified
0.000 0.495 0.504
G36.8 Other specified acute disseminated demyelination
0.000 0.495 0.504
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.495 0.504
E50.9 Vitamin A deficiency, unspecified
0.000 0.496 0.504
E50.8 Other manifestations of vitamin A deficiency
0.000 0.496 0.504
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.496 0.504
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.496 0.504
E50.5 Vitamin A deficiency with night blindness
0.000 0.496 0.504
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.496 0.504
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.496 0.504
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.496 0.504
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.496 0.504
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.496 0.504
E63.9 Nutritional deficiency, unspecified
0.000 0.496 0.504
E63.8 Other specified nutritional deficiencies
0.000 0.496 0.504
E63.1 Imbalance of constituents of food intake
0.000 0.496 0.504
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.496 0.504
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.496 0.504
E64.8 Sequelae of other nutritional deficiencies
0.000 0.496 0.504
E64.3 Sequelae of rickets
0.000 0.496 0.504
E64.2 Sequelae of vitamin C deficiency
0.000 0.496 0.504
E64.1 Sequelae of vitamin A deficiency
0.000 0.496 0.504
E64.0 Sequelae of protein-energy malnutrition
0.000 0.496 0.504
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.498 0.502
D55 Anaemia due to enzyme disorders
0.000 0.499 0.501
E29 Testicular dysfunction
0.000 0.500 0.500
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.500 0.500
E24.3 Ectopic ACTH syndrome
0.000 0.500 0.500
E24.1 Nelson's syndrome
0.000 0.500 0.500
E31.9 Polyglandular dysfunction, unspecified
0.000 0.501 0.499
E31.8 Other polyglandular dysfunction
0.000 0.501 0.499
E31.1 Polyglandular hyperfunction
0.000 0.501 0.499
G36.0 Neuromyelitis optica [Devic]
0.000 0.501 0.499
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.503 0.497
E51.9 Thiamine deficiency, unspecified
0.000 0.506 0.494
E51.8 Other manifestations of thiamine deficiency
0.000 0.506 0.494
E51.1 Beriberi
0.000 0.506 0.494
D81.9 Combined immunodeficiency, unspecified
0.000 0.507 0.492
D81.8 Other combined immunodeficiencies
0.000 0.507 0.492
D81.7 Major histocompatibility complex class II deficiency
0.000 0.507 0.492
D81.6 Major histocompatibility complex class I deficiency
0.000 0.507 0.492
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.507 0.492
D81.4 Nezelof's syndrome
0.000 0.507 0.492
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.507 0.492
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.507 0.492
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.507 0.492
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.507 0.492
E07.1 Dyshormogenetic goitre
0.000 0.513 0.487
E07.0 Hypersecretion of calcitonin
0.000 0.513 0.487
E30.9 Disorder of puberty, unspecified
0.000 0.514 0.486
E30.8 Other disorders of puberty
0.000 0.514 0.486
E30.1 Precocious puberty
0.000 0.514 0.486
E30.0 Delayed puberty
0.000 0.514 0.486
E32.9 Disease of thymus, unspecified
0.000 0.514 0.486
E32.8 Other diseases of thymus
0.000 0.514 0.486
E32.1 Abscess of thymus
0.000 0.514 0.486
E32.0 Persistent hyperplasia of thymus
0.000 0.514 0.486
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.514 0.486
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.514 0.486
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.514 0.486
D82.1 Di George's syndrome
0.000 0.514 0.486
D84.1 Defects in the complement system
0.000 0.515 0.485
M06.0 Seronegative rheumatoid arthritis
0.485 0.515 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.484 0.516 0.000
E51.2 Wernicke's encephalopathy
0.000 0.519 0.481
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.479 0.521 0.000
E61.2 Magnesium deficiency
0.000 0.521 0.479
E34.5 Androgen resistance syndrome
0.000 0.523 0.477
E34.4 Constitutional tall stature
0.000 0.523 0.477
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.523 0.477
E34.1 Other hypersecretion of intestinal hormones
0.000 0.523 0.477
D60-D64 Aplastic and other anaemias
0.000 0.523 0.477
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.526 0.474
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.530 0.470
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.530 0.470
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.530 0.470
D82.2 Immunodeficiency with short-limbed stature
0.000 0.530 0.470
D82.0 Wiskott-Aldrich syndrome
0.000 0.530 0.470
D53.8 Other specified nutritional anaemias
0.000 0.530 0.469
D53.2 Scorbutic anaemia
0.000 0.530 0.469
D53.0 Protein deficiency anaemia
0.000 0.530 0.469
E13.3 With ophthalmic complications
0.000 0.536 0.463
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.458 0.542 0.000
D57 Sickle-cell disorders
0.000 0.543 0.457
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.544 0.456
M06.34 Rheumatoid nodule (Hand)
0.456 0.544 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.453 0.547 0.000
D59.8 Other acquired haemolytic anaemias
0.000 0.548 0.452
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.548 0.452
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.548 0.452
D59.3 Haemolytic-uraemic syndrome
0.000 0.548 0.452
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.548 0.452
M06.98 Rheumatoid arthritis, unspecified (Other)
0.451 0.549 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.551 0.449
E61.8 Deficiency of other specified nutrient elements
0.000 0.551 0.449
E61.7 Deficiency of multiple nutrient elements
0.000 0.551 0.449
E61.6 Vanadium deficiency
0.000 0.551 0.449
E61.5 Molybdenum deficiency
0.000 0.551 0.449
E61.4 Chromium deficiency
0.000 0.551 0.449
E61.3 Manganese deficiency
0.000 0.551 0.449
E61.0 Copper deficiency
0.000 0.551 0.449
D56 Thalassaemia
0.000 0.553 0.447
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.446 0.554 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.443 0.557 0.000
E28.3 Primary ovarian failure
0.000 0.560 0.440
E34.3 Short stature, not elsewhere classified
0.000 0.561 0.439
D52.8 Other folate deficiency anaemias
0.000 0.568 0.432
D52.1 Drug-induced folate deficiency anaemia
0.000 0.568 0.432
D52.0 Dietary folate deficiency anaemia
0.000 0.568 0.432
D53.9 Nutritional anaemia, unspecified
0.000 0.570 0.430
E07.8 Other specified disorders of thyroid
0.000 0.570 0.430
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.429 0.571 0.000
I77.1 Stricture of artery
0.000 0.574 0.426
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.420 0.580 0.000
M07 Psoriatic and enteropathic arthropathies
0.419 0.581 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.581 0.418
E23.2 Diabetes insipidus
0.000 0.582 0.418
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.418 0.582 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.417 0.583 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.416 0.584 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.413 0.587 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.412 0.588 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.592 0.408
E25.8 Other adrenogenital disorders
0.000 0.592 0.408
E44.1 Mild protein-energy malnutrition
0.000 0.593 0.407
E44.0 Moderate protein-energy malnutrition
0.000 0.593 0.407
M05.1 Rheumatoid lung disease
0.406 0.594 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.598 0.401
E28.8 Other ovarian dysfunction
0.000 0.598 0.401
E28.1 Androgen excess
0.000 0.598 0.401
E28.0 Oestrogen excess
0.000 0.598 0.401
I77 Other disorders of arteries and arterioles
0.000 0.598 0.402
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.401 0.599 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.600 0.400
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.600 0.400
M06.32 Rheumatoid nodule (Upper arm)
0.399 0.601 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.602 0.397
M06.33 Rheumatoid nodule (Forearm)
0.397 0.603 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.396 0.604 0.000
M05.8 Other seropositive rheumatoid arthritis
0.394 0.605 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.394 0.605 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.392 0.608 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.609 0.391
I77.8 Other specified disorders of arteries and arterioles
0.000 0.616 0.384
M06.1 Adult-onset Still's disease
0.383 0.616 0.000
M05.2 Rheumatoid vasculitis
0.383 0.617 0.000
D84.9 Immunodeficiency, unspecified
0.000 0.617 0.383
M06.30 Rheumatoid nodule (Multiple sites)
0.383 0.617 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.382 0.618 0.000
M05.0 Felty's syndrome
0.382 0.618 0.000
M06.2 Rheumatoid bursitis
0.382 0.618 0.000
E06.9 Thyroiditis, unspecified
0.000 0.620 0.380
M08 Juvenile arthritis
0.379 0.621 0.000
E06.1 Subacute thyroiditis
0.000 0.622 0.378
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.378 0.622 0.000
I77.6 Arteritis, unspecified
0.000 0.623 0.377
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.376 0.624 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.627 0.372
E22.8 Other hyperfunction of pituitary gland
0.000 0.627 0.372
M09 Juvenile arthritis in diseases classified elsewhere
0.370 0.630 0.000
E26.8 Other hyperaldosteronism
0.000 0.631 0.368
E26.1 Secondary hyperaldosteronism
0.000 0.631 0.368
E24.2 Drug-induced Cushing's syndrome
0.000 0.633 0.366
M06.39 Rheumatoid nodule (Site unspecified)
0.366 0.634 0.000
M06.38 Rheumatoid nodule (Other)
0.366 0.634 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.366 0.634 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.366 0.634 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.634 0.366
E23.6 Other disorders of pituitary gland
0.000 0.635 0.365
E06.4 Drug-induced thyroiditis
0.000 0.636 0.363
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.636 0.363
E06.0 Acute thyroiditis
0.000 0.636 0.363
M14 Arthropathies in other diseases classified elsewhere
0.364 0.636 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.363 0.637 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.637 0.363
E23.1 Drug-induced hypopituitarism
0.000 0.637 0.363
M06.8 Other specified rheumatoid arthritis
0.363 0.637 0.000
E06.5 Other chronic thyroiditis
0.000 0.639 0.360
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.640 0.360
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.641 0.359
D55.8 Other anaemias due to enzyme disorders
0.000 0.641 0.359
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.641 0.359
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.641 0.359
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.641 0.359
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.641 0.359
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.359 0.641 0.000
D58 Other hereditary haemolytic anaemias
0.000 0.641 0.358
E29.8 Other testicular dysfunction
0.000 0.641 0.358
E29.0 Testicular hyperfunction
0.000 0.641 0.358
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.357 0.643 0.000
M11 Other crystal arthropathies
0.355 0.645 0.000
M07.3 Other psoriatic arthropathies
0.353 0.647 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.647 0.353
D62 Acute posthaemorrhagic anaemia
0.000 0.648 0.352
D64 Other anaemias
0.000 0.649 0.351
M06.04 Seronegative rheumatoid arthritis (Hand)
0.350 0.650 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.349 0.651 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.348 0.652 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.348 0.652 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.348 0.652 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.659 0.341
M06.4 Inflammatory polyarthropathy
0.328 0.672 0.000
D57.8 Other sickle-cell disorders
0.000 0.672 0.328
D57.3 Sickle-cell trait
0.000 0.672 0.328
D57.2 Double heterozygous sickling disorders
0.000 0.672 0.328
D57.0 Sickle-cell anaemia with crisis
0.000 0.672 0.328
E65-E68 Obesity and other hyperalimentation
0.000 0.674 0.326
D52.9 Folate deficiency anaemia, unspecified
0.000 0.677 0.323
E61.1 Iron deficiency
0.000 0.677 0.323
D56.9 Thalassaemia, unspecified
0.000 0.679 0.321
D56.8 Other thalassaemias
0.000 0.679 0.321
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.679 0.321
D56.2 Delta-beta thalassaemia
0.000 0.679 0.321
D56.0 Alpha thalassaemia
0.000 0.679 0.321
E22.0 Acromegaly and pituitary gigantism
0.000 0.680 0.319
E29.9 Testicular dysfunction, unspecified
0.000 0.682 0.318
M05.19 Rheumatoid lung disease (Site unspecified)
0.315 0.685 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.686 0.314
D61 Other aplastic anaemias
0.000 0.699 0.301
M07.5 Arthropathy in ulcerative colitis
0.300 0.700 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.300 0.700 0.000
M07.2 Psoriatic spondylitis
0.300 0.700 0.000
M07.1 Arthritis mutilans
0.300 0.700 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.300 0.700 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.700 0.299
D56.1 Beta thalassaemia
0.000 0.701 0.298
I77.2 Rupture of artery
0.000 0.701 0.299
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.294 0.706 0.000
D56.3 Thalassaemia trait
0.000 0.706 0.293
M07.6 Other enteropathic arthropathies
0.293 0.706 0.000
M05.18 Rheumatoid lung disease (Other)
0.291 0.709 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.291 0.709 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.291 0.709 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.291 0.709 0.000
M05.14 Rheumatoid lung disease (Hand)
0.291 0.709 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.291 0.709 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.291 0.709 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.291 0.709 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.291 0.709 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.709 0.291
I77.5 Necrosis of artery
0.000 0.712 0.288
I77.4 Coeliac artery compression syndrome
0.000 0.712 0.288
D72 Other disorders of white blood cells
0.000 0.713 0.287
M07.39 Other psoriatic arthropathies (Site unspecified)
0.286 0.714 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.284 0.716 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.284 0.716 0.000
M12 Other specific arthropathies
0.284 0.716 0.000
D57.1 Sickle-cell anaemia without crisis
0.000 0.716 0.283
D64.8 Other specified anaemias
0.000 0.716 0.284
M05.88 Other seropositive rheumatoid arthritis (Other)
0.283 0.717 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.283 0.717 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.283 0.717 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.283 0.717 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.283 0.717 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.283 0.717 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.283 0.717 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.283 0.717 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.282 0.717 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.718 0.282
M08.0 Juvenile rheumatoid arthritis
0.281 0.719 0.000
I77.3 Arterial fibromuscular dysplasia
0.000 0.721 0.279
M11.9 Crystal arthropathy, unspecified
0.277 0.723 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.276 0.724 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.276 0.724 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.276 0.724 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.275 0.725 0.000
M06.18 Adult-onset Still's disease (Other)
0.275 0.725 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.275 0.725 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.275 0.725 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.275 0.725 0.000
M06.14 Adult-onset Still's disease (Hand)
0.275 0.725 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.275 0.725 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.275 0.725 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.275 0.725 0.000
M05.28 Rheumatoid vasculitis (Other)
0.275 0.725 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.275 0.725 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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