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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10493807
log Bayes Factor = 10.1493
Chromosome 1   position 88,622,731  (GRCh37) Explore rs10493807 on Ensembl!
Variant rs10493807 is part of Cluster X0086

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C34 Malignant neoplasm of bronchus and lung
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
1.000 0.000 0.000
C34.9 Bronchus or lung, unspecified
1.000 0.000 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
1.000 0.000 0.000
C34.1 Upper lobe, bronchus or lung
0.997 0.003 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.995 0.005 0.000
C77.1 Intrathoracic lymph nodes
0.981 0.019 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.975 0.025 0.000
Chapter IX Diseases of the circulatory system
0.965 0.035 0.000
I30-I52 Other forms of heart disease
0.964 0.036 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.959 0.041 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.958 0.042 0.000
I42 Cardiomyopathy
0.953 0.047 0.000
I71 Aortic aneurysm and dissection
0.945 0.055 0.000
C64-C68 Malignant neoplasms of urinary tract
0.941 0.059 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.936 0.064 0.000
I49 Other cardiac arrhythmias
0.930 0.070 0.000
I35 Nonrheumatic aortic valve disorders
0.921 0.079 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.920 0.080 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.920 0.080 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.918 0.082 0.000
I42.9 Cardiomyopathy, unspecified
0.902 0.098 0.000
C77.0 Lymph nodes of head, face and neck
0.898 0.102 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.893 0.107 0.000
I78 Diseases of capillaries
0.887 0.113 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.885 0.115 0.000
C77.4 Inguinal and lower limb lymph nodes
0.877 0.123 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.877 0.123 0.000
I87 Other disorders of veins
0.875 0.125 0.000
D00-D09 In situ neoplasms
0.871 0.129 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.871 0.129 0.000
I44 Atrioventricular and left bundle-branch block
0.870 0.130 0.000
C77.5 Intrapelvic lymph nodes
0.867 0.133 0.000
C67 Malignant neoplasm of bladder
0.865 0.135 0.000
I10-I15 Hypertensive diseases
0.864 0.136 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.863 0.137 0.000
I35.1 Aortic (valve) insufficiency
0.860 0.140 0.000
I87.1 Compression of vein
0.852 0.148 0.000
C79.6 Secondary malignant neoplasm of ovary
0.848 0.152 0.000
I49.9 Cardiac arrhythmia, unspecified
0.848 0.152 0.000
C71 Malignant neoplasm of brain
0.845 0.155 0.000
I42.0 Dilated cardiomyopathy
0.842 0.158 0.000
# Top node
0.839 0.161 0.000
C34.3 Lower lobe, bronchus or lung
0.837 0.163 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.834 0.166 0.000
I31 Other diseases of pericardium
0.831 0.169 0.000
C51-C58 Malignant neoplasms of female genital organs
0.824 0.176 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.823 0.177 0.000
I78.1 Naevus, nonneoplastic
0.821 0.179 0.000
C34.0 Main bronchus
0.819 0.181 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.819 0.181 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.818 0.182 0.000
I49.3 Ventricular premature depolarisation
0.814 0.186 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.809 0.191 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.809 0.191 0.000
I44.7 Left bundle-branch block, unspecified
0.808 0.192 0.000
D04 Carcinoma in situ of skin
0.802 0.198 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.801 0.199 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.801 0.199 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.794 0.206 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.791 0.209 0.000
I35.9 Aortic valve disorder, unspecified
0.790 0.210 0.000
C32 Malignant neoplasm of larynx
0.777 0.223 0.000
I77 Other disorders of arteries and arterioles
0.767 0.233 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.764 0.236 0.000
I49.5 Sick sinus syndrome
0.758 0.242 0.000
C67.9 Bladder, unspecified
0.756 0.244 0.000
I83 Varicose veins of lower extremities
0.755 0.245 0.000
I49.8 Other specified cardiac arrhythmias
0.753 0.247 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.751 0.249 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.748 0.252 0.000
C78.0 Secondary malignant neoplasm of lung
0.747 0.253 0.000
C54 Malignant neoplasm of corpus uteri
0.743 0.257 0.000
I74 Arterial embolism and thrombosis
0.738 0.262 0.000
I42.2 Other hypertrophic cardiomyopathy
0.733 0.267 0.000
I71.0 Dissection of aorta [any part]
0.732 0.268 0.000
I44.3 Other and unspecified atrioventricular block
0.731 0.269 0.000
I12 Hypertensive renal disease
0.731 0.269 0.000
C67.2 Lateral wall of bladder
0.731 0.269 0.000
Q50-Q56 Congenital malformations of genital organs
0.729 0.271 0.000
C34.2 Middle lobe, bronchus or lung
0.728 0.272 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.724 0.276 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.721 0.279 0.000
C77.8 Lymph nodes of multiple regions
0.720 0.280 0.000
C69 Malignant neoplasm of eye and adnexa
0.720 0.280 0.000
C77.9 Lymph node, unspecified
0.718 0.282 0.000
C34.8 Overlapping lesion of bronchus and lung
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.717 0.283 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.717 0.283 0.000
C31 Malignant neoplasm of accessory sinuses
0.717 0.283 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.717 0.283 0.000
C37 Malignant neoplasm of thymus
0.717 0.283 0.000
C33 Malignant neoplasm of trachea
0.717 0.283 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.716 0.284 0.000
Q80-Q89 Other congenital malformations
0.716 0.284 0.000
I10 Essential (primary) hypertension
0.714 0.286 0.000
I35.8 Other aortic valve disorders
0.714 0.286 0.000
C45 Mesothelioma
0.714 0.286 0.000
L40-L45 Papulosquamous disorders
0.713 0.287 0.000
I42.8 Other cardiomyopathies
0.712 0.287 0.000
I34 Nonrheumatic mitral valve disorders
0.708 0.292 0.000
C79.2 Secondary malignant neoplasm of skin
0.707 0.293 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.706 0.294 0.000
I31.3 Pericardial effusion (noninflammatory)
0.704 0.296 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.703 0.296 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
C71.0 Cerebrum, except lobes and ventricles
0.701 0.299 0.000
I70 Atherosclerosis
0.699 0.301 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.698 0.302 0.000
Chapter VIII Diseases of the ear and mastoid process
0.697 0.303 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.696 0.304 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.695 0.305 0.000
I49.4 Other and unspecified premature depolarisation
0.695 0.305 0.000
L43 Lichen planus
0.694 0.306 0.000
L60-L75 Disorders of skin appendages
0.694 0.306 0.000
I00-I02 Acute rheumatic fever
0.692 0.308 0.000
I52 Other heart disorders in diseases classified elsewhere
0.691 0.309 0.000
I48 Atrial fibrillation and flutter
0.691 0.309 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.691 0.309 0.000
I41 Myocarditis in diseases classified elsewhere
0.691 0.309 0.000
I40 Acute myocarditis
0.691 0.309 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.691 0.309 0.000
I32 Pericarditis in diseases classified elsewhere
0.691 0.309 0.000
C71.2 Temporal lobe
0.688 0.312 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.685 0.315 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.683 0.317 0.000
I42.6 Alcoholic cardiomyopathy
0.683 0.317 0.000
I42.5 Other restrictive cardiomyopathy
0.683 0.317 0.000
I42.4 Endocardial fibroelastosis
0.683 0.317 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.683 0.317 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.681 0.319 0.000
L43.9 Lichen planus, unspecified
0.681 0.319 0.000
D04.6 Skin of upper limb, including shoulder
0.678 0.322 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.677 0.323 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.677 0.323 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.677 0.323 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.677 0.323 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.677 0.323 0.000
I33 Acute and subacute endocarditis
0.676 0.323 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.676 0.324 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.675 0.325 0.000
C65 Malignant neoplasm of renal pelvis
0.675 0.325 0.000
I15 Secondary hypertension
0.674 0.326 0.000
I44.0 Atrioventricular block, first degree
0.673 0.327 0.000
D04.7 Skin of lower limb, including hip
0.673 0.327 0.000
C78.2 Secondary malignant neoplasm of pleura
0.672 0.328 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.671 0.328 0.000
C60-C63 Malignant neoplasms of male genital organs
0.671 0.329 0.000
C54.1 Endometrium
0.668 0.332 0.000
I86 Varicose veins of other sites
0.667 0.333 0.000
I49.2 Junctional premature depolarisation
0.667 0.333 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.667 0.333 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.665 0.335 0.000
I77.8 Other specified disorders of arteries and arterioles
0.663 0.337 0.000
C71.1 Frontal lobe
0.662 0.338 0.000
C67.4 Posterior wall of bladder
0.662 0.338 0.000
I05-I09 Chronic rheumatic heart diseases
0.661 0.338 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.661 0.339 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.659 0.340 0.000
C70 Malignant neoplasm of meninges
0.659 0.340 0.000
I36 Nonrheumatic tricuspid valve disorders
0.659 0.341 0.000
C76.0 Head, face and neck
0.659 0.341 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.658 0.342 0.000
I82 Other venous embolism and thrombosis
0.658 0.342 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.656 0.344 0.000
D05 Carcinoma in situ of breast
0.655 0.345 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.655 0.345 0.000
I31.9 Disease of pericardium, unspecified
0.655 0.345 0.000
L72.1 Trichilemmal cyst
0.654 0.346 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.654 0.346 0.000
C71.3 Parietal lobe
0.653 0.347 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.652 0.348 0.000
I72 Other aneurysm
0.651 0.349 0.000
C67.1 Dome of bladder
0.650 0.350 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.650 0.350 0.000
Q51 Congenital malformations of uterus and cervix
0.648 0.352 0.000
C43 Malignant melanoma of skin
0.646 0.354 0.000
H60-H62 Diseases of external ear
0.644 0.356 0.000
I45 Other conduction disorders
0.643 0.357 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.643 0.357 0.000
I87.8 Other specified disorders of veins
0.642 0.358 0.000
I88 Nonspecific lymphadenitis
0.640 0.360 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.640 0.360 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.640 0.360 0.000
I12.0 Hypertensive renal disease with renal failure
0.639 0.361 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.637 0.363 0.000
I78.9 Disease of capillaries, unspecified
0.636 0.364 0.000
I78.8 Other diseases of capillaries
0.636 0.364 0.000
Q28 Other congenital malformations of circulatory system
0.635 0.365 0.000
D50-D53 Nutritional anaemias
0.630 0.370 0.000
N17-N19 Renal failure
0.629 0.371 0.000
C56 Malignant neoplasm of ovary
0.629 0.371 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.629 0.371 0.000
I87.9 Disorder of vein, unspecified
0.627 0.373 0.000
I87.0 Postphlebitic syndrome
0.627 0.373 0.000
C71.9 Brain, unspecified
0.626 0.374 0.000
C66 Malignant neoplasm of ureter
0.626 0.374 0.000
Q21 Congenital malformations of cardiac septa
0.625 0.374 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.625 0.375 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.625 0.375 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.625 0.375 0.000
C46 Kaposi's sarcoma
0.625 0.375 0.000
C67.6 Ureteric orifice
0.624 0.376 0.000
I44.5 Left posterior fascicular block
0.624 0.376 0.000
I44.4 Left anterior fascicular block
0.624 0.376 0.000
I49.0 Ventricular fibrillation and flutter
0.622 0.378 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.622 0.378 0.000
C01 Malignant neoplasm of base of tongue
0.621 0.379 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.621 0.379 0.000
C67.8 Overlapping lesion of bladder
0.620 0.380 0.000
C67.7 Urachus
0.620 0.380 0.000
C67.3 Anterior wall of bladder
0.620 0.380 0.000
C67.0 Trigone of bladder
0.620 0.380 0.000
I95 Hypotension
0.620 0.380 0.000
I13 Hypertensive heart and renal disease
0.619 0.381 0.000
C32.0 Glottis
0.618 0.382 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.618 0.382 0.000
N18 Chronic renal failure
0.617 0.383 0.000
I30 Acute pericarditis
0.617 0.383 0.000
D04.4 Skin of scalp and neck
0.614 0.386 0.000
Chapter XIV Diseases of the genitourinary system
0.614 0.386 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.614 0.386 0.000
N17 Acute renal failure
0.611 0.389 0.000
C04 Malignant neoplasm of floor of mouth
0.609 0.391 0.000
I44.2 Atrioventricular block, complete
0.608 0.392 0.000
D04.3 Skin of other and unspecified parts of face
0.607 0.393 0.000
C71.8 Overlapping lesion of brain
0.606 0.394 0.000
C71.7 Brain stem
0.606 0.394 0.000
C71.6 Cerebellum
0.606 0.394 0.000
C71.5 Cerebral ventricle
0.606 0.394 0.000
C71.4 Occipital lobe
0.606 0.394 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.604 0.396 0.000
I60-I69 Cerebrovascular diseases
0.604 0.396 0.000
C80 Malignant neoplasm without specification of site
0.602 0.398 0.000
H61 Other disorders of external ear
0.601 0.399 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.601 0.399 0.000
N18.9 Chronic renal failure, unspecified
0.598 0.402 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.597 0.403 0.000
D50 Iron deficiency anaemia
0.597 0.403 0.000
I35.0 Aortic (valve) stenosis
0.596 0.404 0.000
I31.8 Other specified diseases of pericardium
0.596 0.404 0.000
I31.2 Haemopericardium, not elsewhere classified
0.596 0.404 0.000
I31.1 Chronic constrictive pericarditis
0.596 0.404 0.000
I31.0 Chronic adhesive pericarditis
0.596 0.404 0.000
N17.9 Acute renal failure, unspecified
0.595 0.405 0.000
C58 Malignant neoplasm of placenta
0.591 0.409 0.000
C52 Malignant neoplasm of vagina
0.591 0.409 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.590 0.410 0.000
Q35-Q37 Cleft lip and cleft palate
0.590 0.410 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.590 0.410 0.000
I20-I25 Ischaemic heart diseases
0.589 0.411 0.000
C45.0 Mesothelioma of pleura
0.588 0.412 0.000
I44.6 Other and unspecified fascicular block
0.585 0.414 0.000
I11 Hypertensive heart disease
0.583 0.417 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.583 0.417 0.000
Q54 Hypospadias
0.580 0.420 0.000
I89.1 Lymphangitis
0.580 0.420 0.000
I81 Portal vein thrombosis
0.579 0.420 0.000
C54.9 Corpus uteri, unspecified
0.579 0.421 0.000
Q27 Other congenital malformations of peripheral vascular system
0.578 0.422 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.578 0.422 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.577 0.423 0.000
C69.3 Choroid
0.577 0.423 0.000
Q24 Other congenital malformations of heart
0.576 0.424 0.000
D09 Carcinoma in situ of other and unspecified sites
0.575 0.425 0.000
L72.0 Epidermal cyst
0.575 0.425 0.000
D04.9 Skin, unspecified
0.575 0.425 0.000
D04.8 Skin of other sites
0.575 0.425 0.000
D04.5 Skin of trunk
0.575 0.425 0.000
D04.2 Skin of ear and external auricular canal
0.575 0.425 0.000
D04.1 Skin of eyelid, including canthus
0.575 0.425 0.000
D04.0 Skin of lip
0.575 0.425 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.574 0.425 0.000
C76.7 Other ill-defined sites
0.574 0.425 0.000
C76.5 Lower limb
0.574 0.425 0.000
C76.4 Upper limb
0.574 0.425 0.000
C76.3 Pelvis
0.574 0.425 0.000
C76.2 Abdomen
0.574 0.425 0.000
C76.1 Thorax
0.574 0.425 0.000
Q51.3 Bicornate uterus
0.572 0.428 0.000
L10-L14 Bullous disorders
0.572 0.428 0.000
C49.3 Connective and soft tissue of thorax
0.569 0.431 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.569 0.431 0.000
C13 Malignant neoplasm of hypopharynx
0.569 0.431 0.000
C11 Malignant neoplasm of nasopharynx
0.569 0.431 0.000
C10 Malignant neoplasm of oropharynx
0.569 0.431 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.569 0.431 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.569 0.431 0.000
C05 Malignant neoplasm of palate
0.569 0.431 0.000
C03 Malignant neoplasm of gum
0.569 0.431 0.000
C00 Malignant neoplasm of lip
0.569 0.431 0.000
C12 Malignant neoplasm of pyriform sinus
0.569 0.431 0.000
Chapter XXII Codes for special purposes
0.566 0.433 0.000
I95.1 Orthostatic hypotension
0.565 0.435 0.000
L20-L30 Dermatitis and eczema
0.563 0.437 0.000
C07 Malignant neoplasm of parotid gland
0.562 0.438 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.560 0.439 0.000
Q00-Q07 Congenital malformations of the nervous system
0.560 0.439 0.000
D50.8 Other iron deficiency anaemias
0.560 0.440 0.000
I51 Complications and ill-defined descriptions of heart disease
0.560 0.440 0.000
N19 Unspecified renal failure
0.559 0.441 0.000
Q89 Other congenital malformations, not elsewhere classified
0.558 0.442 0.000
C32.8 Overlapping lesion of larynx
0.557 0.442 0.000
C32.3 Laryngeal cartilage
0.557 0.442 0.000
C32.2 Subglottis
0.557 0.442 0.000
C32.1 Supraglottis
0.557 0.442 0.000
C32.9 Larynx, unspecified
0.557 0.443 0.000
Q83 Congenital malformations of breast
0.554 0.445 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.554 0.446 0.000
H80-H83 Diseases of inner ear
0.554 0.446 0.000
I74.5 Embolism and thrombosis of iliac artery
0.553 0.446 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.552 0.447 0.000
C67.5 Bladder neck
0.552 0.448 0.000
D06 Carcinoma in situ of cervix uteri
0.552 0.448 0.000
D00.0 Lip, oral cavity and pharynx
0.552 0.448 0.000
I77.5 Necrosis of artery
0.550 0.450 0.000
I77.4 Coeliac artery compression syndrome
0.550 0.450 0.000
I77.3 Arterial fibromuscular dysplasia
0.550 0.450 0.000
I77.2 Rupture of artery
0.550 0.450 0.000
I49.1 Atrial premature depolarisation
0.549 0.451 0.000
I34.0 Mitral (valve) insufficiency
0.549 0.451 0.000
N18.5 Chronic kidney disease, stage 5
0.549 0.451 0.000
I08 Multiple valve diseases
0.548 0.452 0.000
D80-D89 Certain disorders involving the immune mechanism
0.547 0.453 0.000
H61.0 Perichondritis of external ear
0.546 0.453 0.000
I77.1 Stricture of artery
0.546 0.454 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.546 0.454 0.000
I77.0 Arteriovenous fistula, acquired
0.542 0.458 0.000
I61 Intracerebral haemorrhage
0.542 0.458 0.000
D55-D59 Haemolytic anaemias
0.540 0.460 0.000
D60-D64 Aplastic and other anaemias
0.540 0.460 0.000
I45.8 Other specified conduction disorders
0.540 0.460 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.539 0.460 0.000
Q26 Congenital malformations of great veins
0.539 0.461 0.000
Q25 Congenital malformations of great arteries
0.539 0.461 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.539 0.461 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.539 0.461 0.000
D03 Melanoma in situ
0.538 0.462 0.000
I15.1 Hypertension secondary to other renal disorders
0.538 0.462 0.000
I24 Other acute ischaemic heart diseases
0.537 0.463 0.000
Q21.0 Ventricular septal defect
0.537 0.463 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.536 0.464 0.000
C51 Malignant neoplasm of vulva
0.535 0.465 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.534 0.466 0.000
I27 Other pulmonary heart diseases
0.534 0.466 0.000
Q60-Q64 Congenital malformations of the urinary system
0.534 0.466 0.000
C45.9 Mesothelioma, unspecified
0.533 0.467 0.000
C54.8 Overlapping lesion of corpus uteri
0.532 0.467 0.000
C54.3 Fundus uteri
0.532 0.467 0.000
C54.2 Myometrium
0.532 0.467 0.000
C54.0 Isthmus uteri
0.532 0.467 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.531 0.469 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.530 0.470 0.000
I74.8 Embolism and thrombosis of other arteries
0.529 0.471 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.529 0.471 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.529 0.471 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.529 0.471 0.000
Q85 Phakomatoses, not elsewhere classified
0.527 0.473 0.000
I70.0 Atherosclerosis of aorta
0.523 0.477 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.523 0.477 0.000
Q55 Other congenital malformations of male genital organs
0.523 0.477 0.000
Q53 Undescended testicle
0.523 0.477 0.000
Q52 Other congenital malformations of female genitalia
0.523 0.477 0.000
I46 Cardiac arrest
0.523 0.477 0.000
H61.2 Impacted cerumen
0.523 0.477 0.000
C50-C50 Malignant neoplasm of breast
0.521 0.479 0.000
I12.9 Hypertensive renal disease without renal failure
0.518 0.482 0.000
I38 Endocarditis, valve unspecified
0.518 0.482 0.000
I86.8 Varicose veins of other specified sites
0.517 0.482 0.000
D05.1 Intraductal carcinoma in situ
0.517 0.483 0.000
C48.2 Peritoneum, unspecified
0.517 0.483 0.000
C69.9 Eye, unspecified
0.516 0.484 0.000
C69.8 Overlapping lesion of eye and adnexa
0.516 0.484 0.000
C69.6 Orbit
0.516 0.484 0.000
C69.5 Lachrymal gland and duct
0.516 0.484 0.000
C69.4 Ciliary body
0.516 0.484 0.000
C69.2 Retina
0.516 0.484 0.000
C69.1 Cornea
0.516 0.484 0.000
C69.0 Conjunctiva
0.516 0.484 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.516 0.484 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.514 0.486 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.514 0.486 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.514 0.486 0.000
C30.1 Middle ear
0.514 0.486 0.000
C30.0 Nasal cavity
0.514 0.486 0.000
C31.9 Accessory sinus, unspecified
0.514 0.486 0.000
C31.8 Overlapping lesion of accessory sinuses
0.514 0.486 0.000
C31.3 Sphenoidal sinus
0.514 0.486 0.000
C31.2 Frontal sinus
0.514 0.486 0.000
C31.1 Ethmoidal sinus
0.514 0.486 0.000
C31.0 Maxillary sinus
0.514 0.486 0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.514 0.486 0.000
C38.4 Pleura
0.514 0.486 0.000
C38.3 Mediastinum, part unspecified
0.514 0.486 0.000
C38.2 Posterior mediastinum
0.514 0.486 0.000
C38.1 Anterior mediastinum
0.514 0.486 0.000
C38.0 Heart
0.514 0.486 0.000
C39.9 Ill-defined sites within the respiratory system
0.514 0.486 0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs
0.514 0.486 0.000
C39.0 Upper respiratory tract, part unspecified
0.514 0.486 0.000
I37.1 Pulmonary valve insufficiency
0.514 0.486 0.000
I24.8 Other forms of acute ischaemic heart disease
0.514 0.486 0.000
Q23 Congenital malformations of aortic and mitral valves
0.513 0.487 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.513 0.487 0.000
Q84 Other congenital malformations of integument
0.513 0.487 0.000
Q82 Other congenital malformations of skin
0.513 0.487 0.000
Q81 Epidermolysis bullosa
0.513 0.487 0.000
Q80 Congenital ichthyosis
0.513 0.487 0.000
H90-H95 Other disorders of ear
0.513 0.487 0.000
C77.2 Intra-abdominal lymph nodes
0.512 0.488 0.000
C45.7 Mesothelioma of other sites
0.512 0.488 0.000
C45.2 Mesothelioma of pericardium
0.512 0.488 0.000
C45.1 Mesothelioma of peritoneum
0.512 0.488 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.512 0.488 0.000
L44 Other papulosquamous disorders
0.511 0.489 0.000
L41 Parapsoriasis
0.511 0.489 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.511 0.489 0.000
L42 Pityriasis rosea
0.511 0.489 0.000
D07.1 Vulva
0.511 0.489 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.510 0.490 0.000
C57.0 Fallopian tube
0.509 0.491 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.508 0.492 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.508 0.492 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.508 0.492 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.508 0.492 0.000
C43.4 Malignant melanoma of scalp and neck
0.507 0.493 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.506 0.494 0.000
N18.0 End-stage renal disease
0.505 0.495 0.000
I82.2 Embolism and thrombosis of vena cava
0.505 0.495 0.000
I77.6 Arteritis, unspecified
0.504 0.496 0.000
C02.9 Tongue, unspecified
0.503 0.497 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.503 0.497 0.000
I37.9 Pulmonary valve disorder, unspecified
0.503 0.497 0.000
I37.8 Other pulmonary valve disorders
0.503 0.497 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.503 0.497 0.000
I37.0 Pulmonary valve stenosis
0.503 0.497 0.000
Q18 Other congenital malformations of face and neck
0.503 0.497 0.000
I86.1 Scrotal varices
0.502 0.498 0.000
I34.1 Mitral (valve) prolapse
0.502 0.498 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.501 0.499 0.000
Q43 Other congenital malformations of intestine
0.501 0.499 0.000
I70.9 Generalised and unspecified atherosclerosis
0.501 0.499 0.000
I70.8 Atherosclerosis of other arteries
0.501 0.499 0.000
I70.1 Atherosclerosis of renal artery
0.501 0.499 0.000
C53 Malignant neoplasm of cervix uteri
0.501 0.499 0.000
L65 Other nonscarring hair loss
0.501 0.499 0.000
C49.9 Connective and soft tissue, unspecified
0.501 0.499 0.000
C49.8 Overlapping lesion of connective and soft tissue
0.501 0.499 0.000
C49.6 Connective and soft tissue of trunk, unspecified
0.501 0.499 0.000
C49.5 Connective and soft tissue of pelvis
0.501 0.499 0.000
C49.4 Connective and soft tissue of abdomen
0.501 0.499 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.501 0.499 0.000
C49.0 Connective and soft tissue of head, face and neck
0.501 0.499 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.499 0.501 0.000
C95 Leukaemia of unspecified cell type
0.499 0.501 0.000
C94 Other leukaemias of specified cell type
0.499 0.501 0.000
C93 Monocytic leukaemia
0.499 0.501 0.000
C86 Other specified types of T/NK-cell lymphoma
0.499 0.501 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.499 0.501 0.000
I22 Subsequent myocardial infarction
0.499 0.501 0.000
C09 Malignant neoplasm of tonsil
0.499 0.501 0.000
C90.0 Multiple myeloma
0.499 0.501 0.000
D53 Other nutritional anaemias
0.498 0.501 0.000
L43.8 Other lichen planus
0.497 0.502 0.000
L43.3 Subacute (active) lichen planus
0.497 0.502 0.000
L43.2 Lichenoid drug reaction
0.497 0.502 0.000
L43.1 Bullous lichen planus
0.497 0.502 0.000
L43.0 Hypertrophic lichen planus
0.497 0.502 0.000
L75 Apocrine sweat disorders
0.497 0.503 0.000
L74 Eccrine sweat disorders
0.497 0.503 0.000
L70 Acne
0.497 0.503 0.000
L68 Hypertrichosis
0.497 0.503 0.000
L67 Hair colour and hair shaft abnormalities
0.497 0.503 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.497 0.503 0.000
L64 Androgenic alopecia
0.497 0.503 0.000
L63 Alopecia areata
0.497 0.503 0.000
L62 Nail disorders in diseases classified elsewhere
0.497 0.503 0.000
I02 Rheumatic chorea
0.496 0.504 0.000
I01 Rheumatic fever with heart involvement
0.496 0.504 0.000
I00 Rheumatic fever without mention of heart involvement
0.496 0.504 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.496 0.504 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.495 0.504 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.495 0.504 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.495 0.504 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.495 0.504 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.495 0.504 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.495 0.504 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.495 0.504 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.495 0.504 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.495 0.504 0.000
I40.9 Acute myocarditis, unspecified
0.495 0.504 0.000
I40.8 Other acute myocarditis
0.495 0.504 0.000
I40.1 Isolated myocarditis
0.495 0.504 0.000
I40.0 Infective myocarditis
0.495 0.504 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.495 0.504 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.495 0.504 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.495 0.504 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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