TreeWAS – Variant ID: rs10498633

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.018	0.982	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.017	0.983	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.017	0.983	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.016	0.984	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.016	0.984	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.016	0.984	0.000
D86.9 Sarcoidosis, unspecified	0.016	0.984	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.015	0.985	0.000
D86 Sarcoidosis	0.015	0.985	0.000
D86.0 Sarcoidosis of lung	0.015	0.985	0.000
D69.6 Thrombocytopenia, unspecified	0.014	0.986	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.014	0.986	0.000
D86.1 Sarcoidosis of lymph nodes	0.013	0.986	0.000
D69 Purpura and other haemorrhagic conditions	0.013	0.987	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.012	0.988	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.012	0.988	0.000
S42.00 Fracture of clavicle (closed)	0.011	0.989	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.011	0.989	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.011	0.989	0.000
D80-D89 Certain disorders involving the immune mechanism	0.011	0.989	0.000
D69.5 Secondary thrombocytopenia	0.011	0.989	0.000
D69.2 Other nonthrombocytopenic purpura	0.010	0.990	0.000
D69.0 Allergic purpura	0.010	0.990	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.010	0.990	0.000
I51.9 Heart disease, unspecified	0.010	0.990	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.010	0.990	0.000
D86.8 Sarcoidosis of other and combined sites	0.009	0.991	0.000
D69.8 Other specified haemorrhagic conditions	0.009	0.991	0.000
D69.1 Qualitative platelet defects	0.009	0.991	0.000
D86.3 Sarcoidosis of skin	0.009	0.991	0.000
O14.9 Preeclampsia, unspecified	0.000	0.991	0.009
D80 Immunodeficiency with predominantly antibody defects	0.009	0.991	0.000
D69.9 Haemorrhagic condition, unspecified	0.009	0.991	0.000
D84 Other immunodeficiencies	0.008	0.992	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.008	0.992	0.000
D75 Other diseases of blood and blood-forming organs	0.008	0.992	0.000
D81 Combined immunodeficiencies	0.008	0.992	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.008	0.992	0.000
D82 Immunodeficiency associated with other major defects	0.008	0.992	0.000
D69.4 Other primary thrombocytopenia	0.008	0.992	0.000
I51.0 Cardiac septal defect, acquired	0.008	0.992	0.000
D83 Common variable immunodeficiency	0.007	0.993	0.000
D68.2 Hereditary deficiency of other clotting factors	0.007	0.993	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.007	0.993	0.000
D75.0 Familial erythrocytosis	0.007	0.993	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.007	0.993	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.007	0.993	0.000
D72 Other disorders of white blood cells	0.007	0.993	0.000
I51 Complications and ill-defined descriptions of heart disease	0.007	0.993	0.000
D67 Hereditary factor IX deficiency	0.007	0.993	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.993	0.007
D75.9 Disease of blood and blood-forming organs, unspecified	0.007	0.993	0.000
D72.1 Eosinophilia	0.007	0.993	0.000
D75.1 Secondary polycythaemia	0.007	0.993	0.000
D68 Other coagulation defects	0.007	0.993	0.000
D76.3 Other histiocytosis syndromes	0.007	0.993	0.000
D55-D59 Haemolytic anaemias	0.007	0.993	0.000
D75.2 Essential thrombocytosis	0.007	0.993	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.993	0.007
I51.4 Myocarditis, unspecified	0.007	0.993	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.006	0.993	0.000
D84.9 Immunodeficiency, unspecified	0.006	0.993	0.000
I51.6 Cardiovascular disease, unspecified	0.007	0.993	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.006	0.993	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.006	0.993	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.006	0.993	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.006	0.993	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.006	0.993	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.006	0.993	0.000
D66 Hereditary factor VIII deficiency	0.006	0.994	0.000
C50.1 Central portion of breast	0.000	0.994	0.006
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.006	0.994	0.000
D84.8 Other specified immunodeficiencies	0.006	0.994	0.000
D84.1 Defects in the complement system	0.006	0.994	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.006	0.994	0.000
D81.9 Combined immunodeficiency, unspecified	0.006	0.994	0.000
D81.8 Other combined immunodeficiencies	0.006	0.994	0.000
D81.7 Major histocompatibility complex class II deficiency	0.006	0.994	0.000
D81.6 Major histocompatibility complex class I deficiency	0.006	0.994	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.006	0.994	0.000
D81.4 Nezelof's syndrome	0.006	0.994	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.006	0.994	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.006	0.994	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.006	0.994	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.006	0.994	0.000
D74 Methaemoglobinaemia	0.006	0.994	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.006	0.994	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.006	0.994	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.006	0.994	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.006	0.994	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.006	0.994	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.006	0.994	0.000
D82.2 Immunodeficiency with short-limbed stature	0.006	0.994	0.000
D82.0 Wiskott-Aldrich syndrome	0.006	0.994	0.000
D82.1 Di George's syndrome	0.006	0.994	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.994	0.006
D80.1 Nonfamilial hypogammaglobulinaemia	0.006	0.994	0.000
D57 Sickle-cell disorders	0.006	0.994	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.006	0.994	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.006	0.994	0.000
D83.8 Other common variable immunodeficiencies	0.005	0.994	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.005	0.994	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.005	0.994	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.005	0.994	0.000
D68.1 Hereditary factor XI deficiency	0.005	0.995	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.005	0.995	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.005	0.995	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.005	0.995	0.000
D72.9 Disorder of white blood cells, unspecified	0.005	0.995	0.000
D72.0 Genetic anomalies of leukocytes	0.005	0.995	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
I51.5 Myocardial degeneration	0.005	0.995	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.005	0.995	0.000
O14.1 Severe preeclampsia	0.000	0.995	0.005
D56 Thalassaemia	0.005	0.995	0.000
D72.8 Other specified disorders of white blood cells	0.005	0.995	0.000
D59 Acquired haemolytic anaemia	0.005	0.995	0.000
D55 Anaemia due to enzyme disorders	0.005	0.995	0.000
S42.0 Fracture of clavicle	0.005	0.995	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.005	0.995	0.000
D83.9 Common variable immunodeficiency, unspecified	0.005	0.995	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.005	0.995	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.005	0.995	0.000
D68.0 Von Willebrand's disease	0.005	0.995	0.000
D68.4 Acquired coagulation factor deficiency	0.005	0.995	0.000
D57.1 Sickle-cell anaemia without crisis	0.005	0.995	0.000
D73 Diseases of spleen	0.005	0.995	0.000
D68.6 Other Thrombophilia	0.005	0.995	0.000
M81.4 Drug-induced osteoporosis	0.000	0.995	0.005
T85.2 Mechanical complication of intraocular lens	0.004	0.995	0.001
D58 Other hereditary haemolytic anaemias	0.005	0.995	0.000
D68.8 Other specified coagulation defects	0.005	0.995	0.000
D74.9 Methaemoglobinaemia, unspecified	0.004	0.995	0.000
D74.8 Other methaemoglobinaemias	0.004	0.995	0.000
D74.0 Congenital methaemoglobinaemia	0.004	0.995	0.000
O14.2 HELLP syndrome	0.000	0.995	0.004
L73.2 Hidradenitis suppurativa	0.005	0.995	0.000
D56.1 Beta thalassaemia	0.004	0.996	0.000
D68.5 Primary Thrombophilia	0.004	0.996	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.996	0.004
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.996	0.004
D57.8 Other sickle-cell disorders	0.004	0.996	0.000
D57.3 Sickle-cell trait	0.004	0.996	0.000
D57.2 Double heterozygous sickling disorders	0.004	0.996	0.000
D57.0 Sickle-cell anaemia with crisis	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.996	0.004
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
D73.9 Disease of spleen, unspecified	0.004	0.996	0.000
D56.9 Thalassaemia, unspecified	0.004	0.996	0.000
D56.8 Other thalassaemias	0.004	0.996	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.004	0.996	0.000
D56.2 Delta-beta thalassaemia	0.004	0.996	0.000
D56.0 Alpha thalassaemia	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
D56.3 Thalassaemia trait	0.004	0.996	0.000
D73.1 Hypersplenism	0.004	0.996	0.000
D59.1 Other autoimmune haemolytic anaemias	0.004	0.996	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.004	0.996	0.000
D59.8 Other acquired haemolytic anaemias	0.004	0.996	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.004	0.996	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.004	0.996	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.004	0.996	0.000
D59.3 Haemolytic-uraemic syndrome	0.004	0.996	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.004	0.996	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.004	0.996	0.000
D73.4 Cyst of spleen	0.004	0.996	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.004	0.996	0.000
D55.8 Other anaemias due to enzyme disorders	0.004	0.996	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.004	0.996	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.004	0.996	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.004	0.996	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.004	0.996	0.000
S42.01 Fracture of clavicle (open)	0.004	0.996	0.000
L73.9 Follicular disorder, unspecified	0.004	0.996	0.000
O14.0 Moderate preeclampsia	0.000	0.996	0.004
J32.9 Chronic sinusitis, unspecified	0.004	0.996	0.000
I51.8 Other ill-defined heart diseases	0.004	0.996	0.000
N64.8 Other specified disorders of breast	0.004	0.996	0.000
D73.2 Chronic congestive splenomegaly	0.004	0.996	0.000
M81.48 Drug-induced osteoporosis (Other)	0.000	0.996	0.003
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.996	0.003
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.996	0.003
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.996	0.003
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.996	0.003
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.996	0.003
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.996	0.003
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.996	0.003
D73.3 Abscess of spleen	0.003	0.996	0.000
C48.2 Peritoneum, unspecified	0.000	0.996	0.004
D58.8 Other specified hereditary haemolytic anaemias	0.003	0.996	0.000
D58.2 Other haemoglobinopathies	0.003	0.996	0.000
D58.1 Hereditary elliptocytosis	0.003	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
D73.8 Other diseases of spleen	0.003	0.996	0.000
L73 Other follicular disorders	0.003	0.996	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.003	0.997	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.997	0.003
E04.9 Non-toxic goitre, unspecified	0.000	0.997	0.003
M54.37 Sciatica (Lumbosacral region)	0.000	0.997	0.003
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.997	0.003
G31.8 Other specified degenerative diseases of nervous system	0.000	0.997	0.003
D58.0 Hereditary spherocytosis	0.003	0.997	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.997	0.003
D73.5 Infarction of spleen	0.003	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
V23.4 Driver injured in traffic accident	0.000	0.997	0.003
C71.9 Brain, unspecified	0.000	0.997	0.003
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
K58.9 Irritable bowel syndrome without diarrhoea	0.003	0.997	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.997	0.003
G30 Alzheimer's disease	0.000	0.997	0.003
J35.1 Hypertrophy of tonsils	0.003	0.997	0.000
D50-D53 Nutritional anaemias	0.003	0.997	0.000
C48.1 Specified parts of peritoneum	0.000	0.997	0.003
C71.2 Temporal lobe	0.000	0.997	0.003
G60.0 Hereditary motor and sensory neuropathy	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.000	0.997	0.003
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.997	0.003
G30-G32 Other degenerative diseases of the nervous system	0.000	0.997	0.003
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.997	0.003
L73.1 Pseudofolliculitis barbae	0.003	0.997	0.000
L73.0 Acne keloid	0.003	0.997	0.000
L73.8 Other specified follicular disorders	0.003	0.997	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.997	0.003
C71 Malignant neoplasm of brain	0.000	0.997	0.003
M54.3 Sciatica	0.000	0.997	0.003
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.997	0.003
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.997	0.003
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
I85.9 Oesophageal varices without bleeding	0.003	0.997	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.997	0.003
G30.8 Other Alzheimer's disease	0.000	0.997	0.002
O21.0 Mild hyperemesis gravidarum	0.003	0.997	0.000
D68.9 Coagulation defect, unspecified	0.002	0.997	0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.000	0.997	0.002
B97.5 Reovirus as the cause of diseases classified to other chapters	0.000	0.997	0.002
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.000	0.997	0.002
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.000	0.997	0.002
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.000	0.997	0.002
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.000	0.997	0.002
C23 Malignant neoplasm of gallbladder	0.002	0.997	0.000
Z34.8 Supervision of other normal pregnancy	0.002	0.998	0.000
D53 Other nutritional anaemias	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.002
C83.3 Large cell (diffuse)	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
G30.1 Alzheimer's disease with late onset	0.000	0.998	0.002
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.998	0.002
C71.4 Occipital lobe	0.000	0.998	0.002
D52 Folate deficiency anaemia	0.002	0.998	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
B18.1 Chronic viral hepatitis B without delta-agent	0.002	0.998	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
Y83.3 Surgical operation with formation of external stoma	0.002	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O15 Eclampsia	0.000	0.998	0.002
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.998	0.002
M54.35 Sciatica (Thoracolumbar region)	0.000	0.998	0.002
M54.34 Sciatica-Thoracic	0.000	0.998	0.002
M54.33 Sciatica-Cervicothoracic	0.000	0.998	0.002
M54.32 Sciatica-Cervical	0.000	0.998	0.002
M54.31 Sciatica-Occipit-atl-axl	0.000	0.998	0.002
M54.30 Sciatica (Multiple sites in spine)	0.000	0.998	0.002
C48.0 Retroperitoneum	0.000	0.998	0.002
E04 Other non-toxic goitre	0.000	0.998	0.002
B35.1 Tinea unguium	0.000	0.998	0.002
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
C71.3 Parietal lobe	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.000	0.998	0.002
M54.36 Sciatica (Lumbar region)	0.000	0.998	0.002
D53.9 Nutritional anaemia, unspecified	0.002	0.998	0.000
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.002	0.998	0.000
A02.0 Salmonella gastro-enteritis	0.002	0.998	0.000
C71.7 Brain stem	0.000	0.998	0.002
C71.1 Frontal lobe	0.000	0.998	0.002
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.998	0.002
O21 Excessive vomiting in pregnancy	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.998	0.002
N48.2 Other inflammatory disorders of penis	0.002	0.998	0.000
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
D52.8 Other folate deficiency anaemias	0.002	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.002	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.002	0.998	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.998	0.002
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
O21.2 Late vomiting of pregnancy	0.002	0.998	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
K55.0 Acute vascular disorders of intestine	0.002	0.998	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
C44.0 Skin of lip	0.000	0.998	0.002
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O15.9 Eclampsia, unspecified as to time period	0.000	0.998	0.002
O15.2 Eclampsia in the puerperium	0.000	0.998	0.002
O15.1 Eclampsia in labour	0.000	0.998	0.002
O15.0 Eclampsia in pregnancy	0.000	0.998	0.002
E04.8 Other specified non-toxic goitre	0.000	0.998	0.002
M47.92 Spondylosis, unspecified (Cervical region)	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.002	0.998	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.002	0.998	0.000
M24.07 Loose body in joint (Ankle and foot)	0.000	0.998	0.002
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.998	0.002
D52.9 Folate deficiency anaemia, unspecified	0.002	0.998	0.000
Z51.8 Other specified medical care	0.002	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
B18 Chronic viral hepatitis	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.002
O21.8 Other vomiting complicating pregnancy	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
C69.9 Eye, unspecified	0.000	0.998	0.002
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.002
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.002
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.002
E07.9 Disorder of thyroid, unspecified	0.000	0.998	0.002
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.002	0.998	0.000
N94.3 Premenstrual tension syndrome	0.002	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.998	0.002
E04.2 Non-toxic multinodular goitre	0.000	0.998	0.002
M17.3 Other posttraumatic gonarthrosis	0.000	0.998	0.002
O12.2 Gestational oedema with proteinuria	0.000	0.998	0.001
C69 Malignant neoplasm of eye and adnexa	0.000	0.998	0.002
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.000	0.998	0.001
B18.9 Chronic viral hepatitis, unspecified	0.001	0.998	0.000
B18.8 Other chronic viral hepatitis	0.001	0.998	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.001	0.998	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.001
Z13.6 Special screening examination for cardiovascular disorders	0.002	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.998	0.000
Z35.6 Supervision of very young primigravida	0.001	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.998	0.000
C83.7 Burkitt's tumour	0.000	0.998	0.001
Q39.4 Oesophageal web	0.001	0.998	0.000
E07 Other disorders of thyroid	0.000	0.998	0.001
I99 Other and unspecified disorders of circulatory system	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.998	0.001
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.001
W57.8 Other specified place	0.001	0.998	0.000
D60-D64 Aplastic and other anaemias	0.001	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.999	0.000
I20.1 Angina pectoris with documented spasm	0.001	0.999	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.001	0.999	0.000
D51.2 Transcobalamin II deficiency	0.001	0.999	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.999	0.000
O86.0 Infection of obstetric surgical wound	0.000	0.999	0.001
L97 Ulcer of lower limb, not elsewhere classified	0.001	0.999	0.000
C69.0 Conjunctiva	0.000	0.999	0.001
K22.8 Other specified diseases of oesophagus	0.000	0.999	0.001
O12.1 Gestational proteinuria	0.000	0.999	0.001
S82.10 Fracture of upper end of tibia (closed)	0.001	0.999	0.000
E00-E07 Disorders of thyroid gland	0.000	0.999	0.001
C69.8 Overlapping lesion of eye and adnexa	0.000	0.999	0.001
C69.5 Lachrymal gland and duct	0.000	0.999	0.001
C69.4 Ciliary body	0.000	0.999	0.001
C69.3 Choroid	0.000	0.999	0.001
C69.2 Retina	0.000	0.999	0.001
C69.1 Cornea	0.000	0.999	0.001
S01.1 Open wound of eyelid and periocular area	0.001	0.999	0.000
A87 Viral meningitis	0.001	0.999	0.000
O16 Unspecified maternal hypertension	0.000	0.999	0.001
E03.8 Other specified hypothyroidism	0.000	0.999	0.001
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.999	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.999	0.001
V23.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.999	0.001
V23.3 Person injured while boarding or alighting	0.000	0.999	0.001
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.999	0.001
V23.1 Passenger injured in nontraffic accident	0.000	0.999	0.001
V23.0 Driver injured in nontraffic accident	0.000	0.999	0.001
Z35.9 Supervision of high-risk pregnancy, unspecified	0.001	0.999	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.999	0.001
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.999	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.999	0.001
E07.1 Dyshormogenetic goitre	0.000	0.999	0.001
E07.0 Hypersecretion of calcitonin	0.000	0.999	0.001
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.999	0.001
B37.3 Candidiasis of vulva and vagina	0.000	0.999	0.001
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.001	0.999	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.001	0.999	0.000
G60 Hereditary and idiopathic neuropathy	0.001	0.999	0.000
A87.2 Lymphocytic choriomeningitis	0.001	0.999	0.000
Z73.8 Other problems related to life-management difficulty	0.000	0.999	0.001
M24.11 Other articular cartilage disorders (Shoulder region)	0.001	0.999	0.000
M79.18 Myalgia (Other)	0.001	0.999	0.000
E05.8 Other thyrotoxicosis	0.000	0.999	0.001
K55.8 Other vascular disorders of intestine	0.001	0.999	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.001	0.999	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
A49.9 Bacterial infection, unspecified	0.001	0.999	0.000
C69.6 Orbit	0.000	0.999	0.001
E07.8 Other specified disorders of thyroid	0.000	0.999	0.001
E29.1 Testicular hypofunction	0.000	0.999	0.001
R25.2 Cramp and spasm	0.001	0.999	0.000
O86.2 Urinary tract infection following delivery	0.000	0.999	0.001
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.999	0.001
Z35.8 Supervision of other high-risk pregnancies	0.001	0.999	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.999	0.001
E00 Congenital iodine-deficiency syndrome	0.000	0.999	0.001
A87.8 Other viral meningitis	0.001	0.999	0.000
A87.1 Adenoviral meningitis	0.001	0.999	0.000
A87.0 Enteroviral meningitis	0.001	0.999	0.000
E05.5 Thyroid crisis or storm	0.000	0.999	0.001
E05.4 Thyrotoxicosis factitia	0.000	0.999	0.001
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.999	0.001
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.999	0.001
C70 Malignant neoplasm of meninges	0.000	0.999	0.001
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.999	0.001
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.000	0.999	0.001
C72.9 Central nervous system, unspecified	0.000	0.999	0.001
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.999	0.001
C72.5 Other and unspecified cranial nerves	0.000	0.999	0.001
C72.4 Acoustic nerve	0.000	0.999	0.001
C72.3 Optic nerve	0.000	0.999	0.001
C72.2 Olfactory nerve	0.000	0.999	0.001
C72.1 Cauda equina	0.000	0.999	0.001
C72.0 Spinal cord	0.000	0.999	0.001
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.001	0.999	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.001	0.999	0.000
O12.0 Gestational oedema	0.000	0.999	0.001
V23.5 Passenger injured in traffic accident	0.000	0.999	0.001
Z73.3 Stress, not elsewhere classified	0.000	0.999	0.001
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.999	0.000
D60.8 Other acquired pure red cell aplasias	0.001	0.999	0.000
D60.1 Transient acquired pure red cell aplasia	0.001	0.999	0.000
D60.0 Chronic acquired pure red cell aplasia	0.001	0.999	0.000
G60.3 Idiopathic progressive neuropathy	0.001	0.999	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.001	0.999	0.000
G60.1 Refsum's disease	0.001	0.999	0.000
K55.2 Angiodysplasia of colon	0.001	0.999	0.000
M81 Osteoporosis without pathological fracture	0.000	0.999	0.001
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
D73.0 Hyposplenism	0.001	0.999	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.999	0.001
J38.4 Oedema of larynx	0.000	0.999	0.001
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.999	0.001
Z35.5 Supervision of elderly primigravida	0.001	0.999	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.999	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.999	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.999	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.999	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.999	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.999	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.999	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.999	0.001
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.001	0.999	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.001	0.999	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.999	0.001
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.999	0.001
C70.9 Meninges, unspecified	0.000	0.999	0.001
C70.1 Spinal meninges	0.000	0.999	0.001
I82.2 Embolism and thrombosis of vena cava	0.001	0.999	0.000
M81.2 Osteoporosis of disuse	0.000	0.999	0.001
M81.0 Postmenopausal osteoporosis	0.000	0.999	0.001
K55 Vascular disorders of intestine	0.001	0.999	0.000
A02.9 Salmonella infection, unspecified	0.001	0.999	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.001	0.999	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.999	0.001
M81.8 Other osteoporosis	0.000	0.999	0.001
M81.6 Localised osteoporosis [Lequesne]	0.000	0.999	0.001
M81.5 Idiopathic osteoporosis	0.000	0.999	0.001
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.999	0.001
M81.1 Postoophorectomy osteoporosis	0.000	0.999	0.001
M93.9 Osteochondropathy, unspecified	0.000	0.999	0.001
N48.6 Balanitis xerotica obliterans	0.000	0.999	0.001
R85.5 Abnormal microbiological findings	0.001	0.999	0.000
O86 Other puerperal infections	0.000	0.999	0.001
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
F12.2 Dependence syndrome	0.001	0.999	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
R47.8 Other and unspecified speech disturbances	0.000	0.999	0.001
Y60.4 During endoscopic examination	0.000	0.999	0.001
E06 Thyroiditis	0.000	0.999	0.001
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.999	0.001
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.999	0.001
J31.0 Chronic rhinitis	0.001	0.999	0.000
K56.2 Volvulus	0.001	0.999	0.000
O86.1 Other infection of genital tract following delivery	0.000	0.999	0.001
M24.16 Other articular cartilage disorders (Lower leg)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations