TreeWAS – Variant ID: rs10498722

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002	0.000
E10-E14 Diabetes mellitus	0.996	0.004	0.000
E10 Insulin-dependent diabetes mellitus	0.994	0.006	0.000
M35 Other systemic involvement of connective tissue	0.993	0.007	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.990	0.010	0.000
M35.0 Sicca syndrome [Sjogren]	0.989	0.011	0.000
E00-E07 Disorders of thyroid gland	0.988	0.012	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.986	0.014	0.000
S90-S99 Injuries to the ankle and foot	0.982	0.018	0.000
T66-T78 Other and unspecified effects of external causes	0.981	0.019	0.000
E10.9 Without complications	0.981	0.019	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.976	0.024	0.000
M24 Other specific joint derangements	0.973	0.027	0.000
Chapter I Certain infectious and parasitic diseases	0.967	0.033	0.000
E20-E35 Disorders of other endocrine glands	0.961	0.039	0.000
T78 Adverse effects, not elsewhere classified	0.950	0.050	0.000
B35-B49 Mycoses	0.950	0.050	0.000
E10.3 With ophthalmic complications	0.947	0.053	0.000
Chapter VII Diseases of the eye and adnexa	0.942	0.058	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.939	0.061	0.000
E27 Other disorders of adrenal gland	0.937	0.063	0.000
H43-H45 Disorders of vitreous body and globe	0.933	0.067	0.000
M86-M90 Other osteopathies	0.931	0.069	0.000
H43 Disorders of vitreous body	0.928	0.072	0.000
B37 Candidiasis	0.927	0.073	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.925	0.075	0.000
M34 Systemic sclerosis	0.924	0.076	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.916	0.084	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.912	0.087	0.000
S92 Fracture of foot, except ankle	0.912	0.088	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.909	0.091	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.908	0.092	0.000
O36 Maternal care for other known or suspected foetal problems	0.908	0.092	0.000
H43.1 Vitreous haemorrhage	0.908	0.092	0.000
B37.0 Candidal stomatitis	0.908	0.092	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.908	0.092	0.000
S40-S49 Injuries to the shoulder and upper arm	0.905	0.095	0.000
M25 Other joint disorders, not elsewhere classified	0.904	0.096	0.000
Chapter XXII Codes for special purposes	0.901	0.099	0.000
E05.9 Thyrotoxicosis, unspecified	0.897	0.103	0.000
Q60-Q64 Congenital malformations of the urinary system	0.892	0.108	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.889	0.111	0.000
M23 Internal derangement of knee	0.888	0.112	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.887	0.113	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.882	0.118	0.000
E27.1 Primary adrenocortical insufficiency	0.880	0.120	0.000
D60-D64 Aplastic and other anaemias	0.877	0.123	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.874	0.126	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.873	0.127	0.000
E16 Other disorders of pancreatic internal secretion	0.871	0.129	0.000
E83.1 Disorders of iron metabolism	0.001	0.133	0.866
A15-A19 Tuberculosis	0.867	0.133	0.000
M22 Disorders of patella	0.866	0.134	0.000
H30-H36 Disorders of choroid and retina	0.863	0.137	0.000
Q50-Q56 Congenital malformations of genital organs	0.862	0.138	0.000
M15-M19 Arthrosis	0.861	0.139	0.000
M89 Other disorders of bone	0.860	0.140	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.860	0.140	0.000
M80-M85 Disorders of bone density and structure	0.858	0.142	0.000
S00-S09 Injuries to the head	0.857	0.143	0.000
H53-H54 Visual disturbances and blindness	0.857	0.143	0.000
S20-S29 Injuries to the thorax	0.856	0.144	0.000
E03 Other hypothyroidism	0.853	0.147	0.000
S92.3 Fracture of metatarsal bone	0.851	0.149	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.851	0.149	0.000
M24.1 Other articular cartilage disorders	0.850	0.150	0.000
D64 Other anaemias	0.850	0.150	0.000
O43 Placental disorders	0.850	0.150	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.848	0.152	0.000
O85-O92 Complications predominantly related to the puerperium	0.848	0.152	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.848	0.152	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.847	0.153	0.000
O47 False labour	0.846	0.154	0.000
T78.2 Anaphylactic shock, unspecified	0.846	0.154	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.846	0.154	0.000
M25.9 Joint disorder, unspecified	0.845	0.155	0.000
E23 Hypofunction and other disorders of pituitary gland	0.845	0.155	0.000
O36.6 Maternal care for excessive foetal growth	0.841	0.159	0.000
T71 Asphyxiation	0.836	0.164	0.000
E16.2 Hypoglycaemia, unspecified	0.836	0.164	0.000
M17 Gonarthrosis [arthrosis of knee]	0.833	0.167	0.000
D64.9 Anaemia, unspecified	0.832	0.168	0.000
M05-M14 Inflammatory polyarthropathies	0.830	0.170	0.000
B02 Zoster [herpes zoster]	0.829	0.171	0.000
H35 Other retinal disorders	0.828	0.172	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.825	0.175	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.824	0.176	0.000
M23.3 Other meniscus derangements	0.822	0.178	0.000
M17.0 Primary gonarthrosis, bilateral	0.822	0.178	0.000
E10.8 With unspecified complications	0.819	0.181	0.000
H35.8 Other specified retinal disorders	0.816	0.184	0.000
E24 Cushing's syndrome	0.816	0.184	0.000
U80 Agent resistant to penicillin and related antibiotics	0.815	0.185	0.000
H43.8 Other disorders of vitreous body	0.814	0.186	0.000
O42 Premature rupture of membranes	0.814	0.186	0.000
E10.7 With multiple complications	0.813	0.187	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.813	0.187	0.000
S10-S19 Injuries to the neck	0.813	0.187	0.000
B00 Herpesviral [herpes simplex] infections	0.813	0.187	0.000
T00-T07 Injuries involving multiple body regions	0.812	0.188	0.000
B37.9 Candidiasis, unspecified	0.811	0.189	0.000
S06 Intracranial injury	0.810	0.190	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.810	0.190	0.000
E27.2 Addisonian crisis	0.809	0.191	0.000
S92.30 Fracture of metatarsal bone (closed)	0.808	0.192	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.807	0.193	0.000
S50-S59 Injuries to the elbow and forearm	0.805	0.195	0.000
M34.1 CR(E)ST syndrome	0.804	0.196	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.801	0.199	0.000
H54 Blindness and low vision	0.798	0.202	0.000
B02.9 Zoster without complication	0.798	0.202	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.795	0.205	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.790	0.210	0.000
E03.9 Hypothyroidism, unspecified	0.789	0.211	0.000
S90 Superficial injury of ankle and foot	0.789	0.211	0.000
T78.3 Angioneurotic oedema	0.787	0.213	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.787	0.213	0.000
T68 Hypothermia	0.786	0.214	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.786	0.214	0.000
M25.7 Osteophyte	0.786	0.214	0.000
M60-M63 Disorders of muscles	0.784	0.216	0.000
Q61 Cystic kidney disease	0.780	0.220	0.000
M24.0 Loose body in joint	0.777	0.223	0.000
E14 Unspecified diabetes mellitus	0.776	0.224	0.000
M24.5 Contracture of joint	0.775	0.225	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.771	0.229	0.000
H43.3 Other vitreous opacities	0.771	0.229	0.000
O46.8 Other antepartum haemorrhage	0.770	0.230	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.770	0.230	0.000
M80 Osteoporosis with pathological fracture	0.769	0.231	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.769	0.231	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.768	0.232	0.000
E10.5 With peripheral circulatory complications	0.768	0.232	0.000
E07 Other disorders of thyroid	0.768	0.232	0.000
M86 Osteomyelitis	0.766	0.234	0.000
B35 Dermatophytosis	0.765	0.234	0.000
S91 Open wound of ankle and foot	0.765	0.235	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.765	0.235	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.765	0.235	0.000
M89.8 Other specified disorders of bone	0.762	0.238	0.000
M25.4 Effusion of joint	0.761	0.239	0.000
M34.9 Systemic sclerosis, unspecified	0.758	0.242	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.758	0.242	0.000
S21 Open wound of thorax	0.757	0.243	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.757	0.243	0.000
M06 Other rheumatoid arthritis	0.756	0.244	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.755	0.245	0.000
U80.1 Methicillin resistant agent	0.753	0.247	0.000
T92 Sequelae of injuries of upper limb	0.753	0.247	0.000
Chapter XX External causes of morbidity and mortality	0.753	0.247	0.000
T93 Sequelae of injuries of lower limb	0.752	0.248	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.751	0.249	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.746	0.254	0.000
M22.8 Other disorders of patella	0.746	0.254	0.000
S93.1 Dislocation of toe(s)	0.745	0.255	0.000
E10.6 With other specified complications	0.744	0.256	0.000
T20 Burn and corrosion of head and neck	0.744	0.256	0.000
T25 Burn and corrosion of ankle and foot	0.743	0.257	0.000
A80-A89 Viral infections of the central nervous system	0.743	0.257	0.000
M18 Arthrosis of first carpometacarpal joint	0.743	0.257	0.000
M87 Osteonecrosis	0.742	0.258	0.000
S92.4 Fracture of great toe	0.741	0.259	0.000
M34.8 Other forms of systemic sclerosis	0.740	0.260	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.738	0.262	0.000
A30-A49 Other bacterial diseases	0.738	0.262	0.000
O41 Other disorders of amniotic fluid and membranes	0.736	0.264	0.000
H43.9 Disorder of vitreous body, unspecified	0.735	0.264	0.000
B36 Other superficial mycoses	0.734	0.266	0.000
B00.5 Herpesviral ocular disease	0.733	0.267	0.000
E34 Other endocrine disorders	0.731	0.269	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.731	0.269	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.731	0.269	0.000
M24.2 Disorder of ligament	0.731	0.269	0.000
S99 Other and unspecified injuries of ankle and foot	0.731	0.269	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.731	0.269	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.730	0.270	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.728	0.272	0.000
T78.8 Other adverse effects, not elsewhere classified	0.728	0.272	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.727	0.273	0.000
O43.8 Other placental disorders	0.726	0.274	0.000
M17.9 Gonarthrosis, unspecified	0.724	0.276	0.000
H35.4 Peripheral retinal degeneration	0.723	0.277	0.000
Q51 Congenital malformations of uterus and cervix	0.723	0.277	0.000
H54.7 Unspecified visual loss	0.723	0.277	0.000
D68 Other coagulation defects	0.722	0.278	0.000
E10.4 With neurological complications	0.722	0.278	0.000
O16 Unspecified maternal hypertension	0.722	0.278	0.000
M23.8 Other internal derangements of knee	0.719	0.281	0.000
S05 Injury of eye and orbit	0.719	0.281	0.000
S40 Superficial injury of shoulder and upper arm	0.718	0.282	0.000
O45 Premature separation of placenta [abruptio placentae]	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
S43.0 Dislocation of shoulder joint	0.716	0.284	0.000
M00-M03 Infectious arthropathies	0.716	0.284	0.000
T33-T35 Frostbite	0.716	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284	0.000
O86 Other puerperal infections	0.715	0.285	0.000
O46.9 Antepartum haemorrhage, unspecified	0.715	0.285	0.000
S92.2 Fracture of other tarsal bone(s)	0.714	0.286	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.714	0.286	0.000
M32 Systemic lupus erythematosus	0.714	0.286	0.000
E12 Malnutrition-related diabetes mellitus	0.714	0.286	0.000
M25.71 Osteophyte (Shoulder region)	0.713	0.287	0.000
E23.6 Other disorders of pituitary gland	0.712	0.288	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.712	0.288	0.000
M35.8 Other specified systemic involvement of connective tissue	0.712	0.288	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.712	0.288	0.000
M35.5 Multifocal fibrosclerosis	0.712	0.288	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.712	0.288	0.000
M35.2 Behcet's disease	0.712	0.288	0.000
S92.7 Multiple fractures of foot	0.710	0.290	0.000
D62 Acute posthaemorrhagic anaemia	0.710	0.290	0.000
O33 Maternal care for known or suspected disproportion	0.710	0.290	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.709	0.291	0.000
E00 Congenital iodine-deficiency syndrome	0.709	0.291	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.709	0.291	0.000
M35.3 Polymyalgia rheumatica	0.707	0.293	0.000
O31 Complications specific to multiple gestation	0.707	0.293	0.000
O44 Placenta praevia	0.706	0.294	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.705	0.295	0.000
B00.9 Herpesviral infection, unspecified	0.705	0.295	0.000
D55-D59 Haemolytic anaemias	0.705	0.295	0.000
V20-V29 Motorcycle rider injured in transport accident	0.705	0.295	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.705	0.295	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.704	0.296	0.000
S98 Traumatic amputation of ankle and foot	0.704	0.296	0.000
S97 Crushing injury of ankle and foot	0.704	0.296	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.704	0.296	0.000
S95 Injury of blood vessels at ankle and foot level	0.704	0.296	0.000
S94 Injury of nerves at ankle and foot level	0.704	0.296	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.704	0.296	0.000
S93.0 Dislocation of ankle joint	0.704	0.296	0.000
T74 Maltreatment syndromes	0.703	0.297	0.000
T73 Effects of other deprivation	0.703	0.297	0.000
T70 Effects of air pressure and water pressure	0.703	0.297	0.000
T69 Other effects of reduced temperature	0.703	0.297	0.000
T67 Effects of heat and light	0.703	0.297	0.000
T66 Unspecified effects of radiation	0.703	0.297	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.703	0.297	0.000
Q60.2 Renal agenesis, unspecified	0.703	0.297	0.000
E04 Other non-toxic goitre	0.703	0.297	0.000
M33 Dermatopolymyositis	0.703	0.297	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.703	0.297	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.702	0.298	0.000
M31 Other necrotising vasculopathies	0.702	0.298	0.000
S06.5 Traumatic subdural haemorrhage	0.702	0.298	0.000
H31 Other disorders of choroid	0.702	0.298	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.701	0.299	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.701	0.299	0.000
B15-B19 Viral hepatitis	0.700	0.300	0.000
M23.4 Loose body in knee	0.700	0.300	0.000
E05.8 Other thyrotoxicosis	0.700	0.300	0.000
E05.5 Thyroid crisis or storm	0.700	0.300	0.000
E05.4 Thyrotoxicosis factitia	0.700	0.300	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.700	0.300	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.700	0.300	0.000
B37.1 Pulmonary candidiasis	0.699	0.301	0.000
M35.1 Other overlap syndromes	0.699	0.301	0.000
E23.7 Disorder of pituitary gland, unspecified	0.698	0.302	0.000
M24.9 Joint derangement, unspecified	0.697	0.303	0.000
M24.7 Protrusio acetabuli	0.697	0.303	0.000
M24.6 Ankylosis of joint	0.697	0.303	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.697	0.303	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.697	0.303	0.000
H34 Retinal vascular occlusions	0.694	0.306	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.693	0.306	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.693	0.306	0.000
A75-A79 Rickettsioses	0.693	0.306	0.000
A70-A74 Other diseases caused by chlamydiae	0.693	0.306	0.000
A65-A69 Other spirochaetal diseases	0.693	0.306	0.000
A20-A28 Certain zoonotic bacterial diseases	0.693	0.306	0.000
E20 Hypoparathyroidism	0.693	0.307	0.000
S29 Other and unspecified injuries of thorax	0.693	0.307	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.692	0.308	0.000
E70-E90 Metabolic disorders	0.692	0.308	0.000
T79-T79 Certain early complications of trauma	0.692	0.308	0.000
Q80-Q89 Other congenital malformations	0.692	0.308	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.691	0.309	0.000
O47.9 False labour, unspecified	0.689	0.311	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.689	0.311	0.000
E32 Diseases of thymus	0.689	0.311	0.000
E31 Polyglandular dysfunction	0.689	0.311	0.000
E30 Disorders of puberty, not elsewhere classified	0.689	0.311	0.000
E25 Adrenogenital disorders	0.689	0.311	0.000
D68.8 Other specified coagulation defects	0.689	0.311	0.000
T23 Burn and corrosion of wrist and hand	0.687	0.313	0.000
O34.4 Maternal care for other abnormalities of cervix	0.686	0.314	0.000
E40-E46 Malnutrition	0.684	0.315	0.000
B44 Aspergillosis	0.684	0.316	0.000
M11 Other crystal arthropathies	0.684	0.316	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.684	0.316	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.683	0.317	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.683	0.317	0.000
Q60.0 Renal agenesis, unilateral	0.683	0.317	0.000
T78.9 Adverse effect, unspecified	0.681	0.319	0.000
B48 Other mycoses, not elsewhere classified	0.681	0.319	0.000
B47 Mycetoma	0.681	0.319	0.000
B46 Zygomycosis	0.681	0.319	0.000
B45 Cryptococcosis	0.681	0.319	0.000
B43 Chromomycosis and phaeomycotic abscess	0.681	0.319	0.000
B42 Sporotrichosis	0.681	0.319	0.000
B41 Paracoccidioidomycosis	0.681	0.319	0.000
B40 Blastomycosis	0.681	0.319	0.000
B39 Histoplasmosis	0.681	0.319	0.000
B38 Coccidioidomycosis	0.681	0.319	0.000
E10.0 With coma	0.680	0.320	0.000
S50 Superficial injury of forearm	0.678	0.322	0.000
M25.74 Osteophyte (Hand)	0.678	0.322	0.000
M85 Other disorders of bone density and structure	0.678	0.322	0.000
Q61.0 Congenital single renal cyst	0.678	0.322	0.000
B49 Unspecified mycosis	0.678	0.322	0.000
T75 Effects of other external causes	0.676	0.324	0.000
O20 Haemorrhage in early pregnancy	0.676	0.324	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.676	0.324	0.000
S41 Open wound of shoulder and upper arm	0.675	0.325	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.674	0.326	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.673	0.327	0.000
Q35-Q37 Cleft lip and cleft palate	0.673	0.327	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.673	0.327	0.000
E27.5 Adrenomedullary hyperfunction	0.672	0.328	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.672	0.328	0.000
E27.0 Other adrenocortical overactivity	0.672	0.328	0.000
M06.9 Rheumatoid arthritis, unspecified	0.672	0.328	0.000
M25.0 Haemarthrosis	0.671	0.329	0.000
O34.3 Maternal care for cervical incompetence	0.671	0.329	0.000
H35.7 Separation of retinal layers	0.670	0.330	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.670	0.330	0.000
B50-B64 Protozoal diseases	0.670	0.330	0.000
O22 Venous complications in pregnancy	0.670	0.330	0.000
M89.9 Disorder of bone, unspecified	0.669	0.331	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.669	0.331	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.669	0.331	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.668	0.331	0.000
B37.2 Candidiasis of skin and nail	0.668	0.332	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.668	0.332	0.000
T00 Superficial injuries involving multiple body regions	0.668	0.332	0.000
M35.7 Hypermobility syndrome	0.667	0.333	0.000
M81 Osteoporosis without pathological fracture	0.667	0.333	0.000
E10.1 With ketoacidosis	0.666	0.334	0.000
H43.2 Crystalline deposits in vitreous body	0.665	0.335	0.000
H43.0 Vitreous prolapse	0.665	0.335	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.665	0.335	0.000
B37.7 Candidal septicaemia	0.664	0.336	0.000
B37.6 Candidal endocarditis	0.664	0.336	0.000
B37.5 Candidal meningitis	0.664	0.336	0.000
M89.3 Hypertrophy of bone	0.664	0.336	0.000
E15 Nondiabetic hypoglycaemic coma	0.663	0.337	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.663	0.337	0.000
M34.0 Progressive systemic sclerosis	0.663	0.337	0.000
H54.0 Blindness, both eyes	0.662	0.338	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.662	0.338	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.661	0.339	0.000
O43.1 Malformation of placenta	0.660	0.340	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.658	0.341	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.657	0.343	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.657	0.343	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.657	0.343	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.657	0.343	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.657	0.343	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.657	0.343	0.000
M22.3 Other derangements of patella	0.657	0.343	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.656	0.344	0.000
W20-W49 Exposure to inanimate mechanical forces	0.655	0.345	0.000
M23.0 Cystic meniscus	0.655	0.345	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.654	0.346	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.654	0.346	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.654	0.346	0.000
O34.6 Maternal care for abnormality of vagina	0.654	0.346	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.654	0.346	0.000
O34.0 Maternal care for congenital malformation of uterus	0.654	0.346	0.000
T14 Injury of unspecified body region	0.654	0.346	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.654	0.346	0.000
S92.9 Fracture of foot, unspecified	0.653	0.346	0.000
S92.5 Fracture of other toe	0.653	0.346	0.000
A40 Streptococcal septicaemia	0.653	0.347	0.000
S14 Injury of nerves and spinal cord at neck level	0.652	0.348	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.652	0.348	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.652	0.348	0.000
Q00-Q07 Congenital malformations of the nervous system	0.652	0.348	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.651	0.349	0.000
E50-E64 Other nutritional deficiencies	0.651	0.349	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.651	0.349	0.000
O36.2 Maternal care for hydrops foetalis	0.651	0.349	0.000
O36.1 Maternal care for other isoimmunisation	0.651	0.349	0.000
H35.2 Other proliferative retinopathy	0.651	0.349	0.000
M06.3 Rheumatoid nodule	0.650	0.349	0.000
M24.02 Loose body in joint (Upper arm)	0.649	0.351	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.649	0.351	0.000
M89.0 Algoneurodystrophy	0.649	0.351	0.000
S48 Traumatic amputation of shoulder and upper arm	0.649	0.351	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.649	0.351	0.000
S44 Injury of nerves at shoulder and upper arm level	0.649	0.351	0.000
S47 Crushing injury of shoulder and upper arm	0.649	0.351	0.000
T92.1 Sequelae of fracture of arm	0.648	0.352	0.000
M25.2 Flail joint	0.648	0.352	0.000
M25.1 Fistula of joint	0.648	0.352	0.000
M86.9 Osteomyelitis, unspecified	0.648	0.352	0.000
O24 Diabetes mellitus in pregnancy	0.647	0.353	0.000
B35.3 Tinea pedis	0.646	0.354	0.000
Q63 Other congenital malformations of kidney	0.646	0.354	0.000
E24.0 Pituitary-dependent Cushing's disease	0.646	0.354	0.000
S06.3 Focal brain injury	0.645	0.355	0.000
E13 Other specified diabetes mellitus	0.645	0.355	0.000
S90.3 Contusion of other and unspecified parts of foot	0.645	0.355	0.000
Q51.3 Bicornate uterus	0.644	0.356	0.000
T16 Foreign body in ear	0.644	0.356	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.644	0.356	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.644	0.356	0.000
B99-B99 Other infectious diseases	0.643	0.357	0.000
B01 Varicella [chickenpox]	0.643	0.357	0.000
X50-X57 Overexertion, travel and privation	0.643	0.357	0.000
S20 Superficial injury of thorax	0.643	0.357	0.000
E27.9 Disorder of adrenal gland, unspecified	0.642	0.358	0.000
A49 Bacterial infection of unspecified site	0.640	0.360	0.000
E14.3 With ophthalmic complications	0.640	0.360	0.000
E24.2 Drug-induced Cushing's syndrome	0.639	0.360	0.000
S21.9 Open wound of thorax, part unspecified	0.639	0.361	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.639	0.361	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.639	0.361	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.638	0.361	0.000
M22.0 Recurrent dislocation of patella	0.638	0.362	0.000
S93.4 Sprain and strain of ankle	0.637	0.363	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.637	0.363	0.000
S93.5 Sprain and strain of toe(s)	0.637	0.363	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.637	0.363	0.000
Q64 Other congenital malformations of urinary system	0.637	0.363	0.000
T20.2 Burn of second degree of head and neck	0.637	0.363	0.000
T09 Other injuries of spine and trunk, level unspecified	0.636	0.363	0.000
B06 Rubella [German measles]	0.636	0.364	0.000
B05 Measles	0.636	0.364	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.636	0.364	0.000
B04 Monkeypox	0.636	0.364	0.000
B03 Smallpox	0.636	0.364	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.635	0.364	0.000
S59 Other and unspecified injuries of forearm	0.635	0.365	0.000
S43.1 Dislocation of acromioclavicular joint	0.635	0.365	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.632	0.367	0.000
M89.5 Osteolysis	0.632	0.368	0.000
O87 Venous complications in the puerperium	0.632	0.368	0.000
M30 Polyarteritis nodosa and related conditions	0.632	0.368	0.000
T21 Burn and corrosion of trunk	0.632	0.368	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.632	0.368	0.000
S06.0 Concussion	0.631	0.369	0.000
E24.9 Cushing's syndrome, unspecified	0.631	0.369	0.000
V23.4 Driver injured in traffic accident	0.631	0.369	0.000
S21.1 Open wound of front wall of thorax	0.630	0.370	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.629	0.371	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.629	0.371	0.000
U80.0 Penicillin resistant agent	0.628	0.372	0.000
M25.8 Other specified joint disorders	0.627	0.372	0.000
H30 Chorioretinal inflammation	0.627	0.372	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.627	0.373	0.000
S54 Injury of nerves at forearm level	0.627	0.373	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.627	0.373	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.627	0.373	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.627	0.373	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.627	0.373	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.627	0.373	0.000
O21 Excessive vomiting in pregnancy	0.626	0.374	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.625	0.375	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.625	0.375	0.000
T25.3 Burn of third degree of ankle and foot	0.625	0.375	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.624	0.375	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.624	0.375	0.000
E16.4 Abnormal secretion of gastrin	0.624	0.375	0.000
E16.3 Increased secretion of glucagon	0.624	0.375	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.624	0.375	0.000
E28 Ovarian dysfunction	0.623	0.377	0.000
M22.4 Chondromalacia patellae	0.623	0.377	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.622	0.378	0.000
Q61.9 Cystic kidney disease, unspecified	0.622	0.378	0.000
A19 Miliary tuberculosis	0.621	0.378	0.000
A18 Tuberculosis of other organs	0.621	0.378	0.000
A17 Tuberculosis of nervous system	0.621	0.378	0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.621	0.378	0.000
M22.1 Recurrent subluxation of patella	0.621	0.379	0.000
M22.9 Disorder of patella, unspecified	0.621	0.379	0.000
S13.4 Sprain and strain of cervical spine	0.621	0.379	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.620	0.379	0.000
B02.2 Zoster with other nervous system involvement	0.620	0.380	0.000
M62 Other disorders of muscle	0.620	0.380	0.000
O23 Infections of genito-urinary tract in pregnancy	0.620	0.380	0.000
M23.1 Discoid meniscus (congenital)	0.620	0.380	0.000
Q53 Undescended testicle	0.620	0.380	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.619	0.380	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.619	0.381	0.000
E23.0 Hypopituitarism	0.619	0.381	0.000
B25-B34 Other viral diseases	0.619	0.381	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.619	0.381	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.618	0.382	0.000
Q55 Other congenital malformations of male genital organs	0.618	0.382	0.000
Q52 Other congenital malformations of female genitalia	0.618	0.382	0.000
M22.2 Patellofemoral disorders	0.618	0.382	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.617	0.383	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations