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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10498727
log Bayes Factor = 5.07836
Chromosome 6   position 25,486,154  (GRCh37) Explore rs10498727 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E83 Disorders of mineral metabolism
0.000 0.161 0.839
E83.5 Disorders of calcium metabolism
0.000 0.270 0.730
E83.4 Disorders of magnesium metabolism
0.000 0.360 0.640
E70-E90 Metabolic disorders
0.000 0.370 0.630
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.378 0.622
E10-E14 Diabetes mellitus
0.000 0.379 0.621
E11 Non-insulin-dependent diabetes mellitus
0.000 0.394 0.606
E00-E07 Disorders of thyroid gland
0.000 0.395 0.605
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.398 0.602
E83.8 Other disorders of mineral metabolism
0.000 0.398 0.602
E83.2 Disorders of zinc metabolism
0.000 0.398 0.602
E83.0 Disorders of copper metabolism
0.000 0.398 0.602
E10 Insulin-dependent diabetes mellitus
0.000 0.398 0.602
E11.3 With ophthalmic complications
0.000 0.405 0.595
E04 Other non-toxic goitre
0.000 0.432 0.568
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.439 0.561
E11.5 With peripheral circulatory complications
0.000 0.445 0.555
E04.9 Non-toxic goitre, unspecified
0.000 0.447 0.553
E06 Thyroiditis
0.000 0.472 0.528
E11.1 With ketoacidosis
0.000 0.479 0.521
E10.9 Without complications
0.000 0.484 0.516
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.494 0.506
E10.2 With renal complications
0.000 0.498 0.502
E13 Other specified diabetes mellitus
0.000 0.499 0.501
E83.3 Disorders of phosphorus metabolism
0.000 0.500 0.500
E10.4 With neurological complications
0.000 0.500 0.500
E10.1 With ketoacidosis
0.000 0.508 0.492
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.514 0.486
E06.3 Autoimmune thyroiditis
0.000 0.516 0.484
E11.6 With other specified complications
0.000 0.519 0.481
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.519 0.481
E20-E35 Disorders of other endocrine glands
0.000 0.520 0.480
E10.3 With ophthalmic complications
0.000 0.523 0.477
E05.9 Thyrotoxicosis, unspecified
0.000 0.525 0.475
E10.0 With coma
0.000 0.526 0.474
E78.0 Pure hypercholesterolaemia
0.000 0.528 0.472
E74 Other disorders of carbohydrate metabolism
0.000 0.530 0.470
E04.2 Non-toxic multinodular goitre
0.000 0.539 0.461
E73 Lactose intolerance
0.000 0.544 0.456
E84 Cystic fibrosis
0.000 0.548 0.452
E77 Disorders of glycoprotein metabolism
0.000 0.548 0.452
E76 Disorders of glycosaminoglycan metabolism
0.000 0.548 0.452
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.548 0.452
E72 Other disorders of amino-acid metabolism
0.000 0.548 0.452
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.548 0.452
E70 Disorders of aromatic amino-acid metabolism
0.000 0.548 0.452
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.548 0.452
E27 Other disorders of adrenal gland
0.000 0.553 0.447
E12 Malnutrition-related diabetes mellitus
0.000 0.554 0.445
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.562 0.438
E79 Disorders of purine and pyrimidine metabolism
0.000 0.562 0.438
E11.7 With multiple complications
0.000 0.565 0.435
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.566 0.434
E00 Congenital iodine-deficiency syndrome
0.000 0.566 0.434
E10.7 With multiple complications
0.000 0.568 0.431
E10.6 With other specified complications
0.000 0.573 0.427
E11.4 With neurological complications
0.000 0.574 0.426
E11.0 With coma
0.000 0.577 0.423
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.578 0.422
E10.8 With unspecified complications
0.000 0.580 0.420
E13.9 Without complications
0.000 0.585 0.415
E04.0 Non-toxic diffuse goitre
0.000 0.590 0.410
E04.8 Other specified non-toxic goitre
0.000 0.593 0.407
E05.8 Other thyrotoxicosis
0.000 0.598 0.402
E05.5 Thyroid crisis or storm
0.000 0.598 0.402
E05.4 Thyrotoxicosis factitia
0.000 0.598 0.402
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.598 0.402
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.598 0.402
E78.1 Pure hyperglyceridaemia
0.000 0.600 0.400
E03 Other hypothyroidism
0.000 0.601 0.399
E26 Hyperaldosteronism
0.000 0.606 0.394
E10.5 With peripheral circulatory complications
0.000 0.607 0.393
E78.8 Other disorders of lipoprotein metabolism
0.000 0.607 0.393
E29 Testicular dysfunction
0.000 0.609 0.391
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.613 0.387
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.613 0.387
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.615 0.385
E16 Other disorders of pancreatic internal secretion
0.000 0.620 0.380
E06.5 Other chronic thyroiditis
0.000 0.621 0.379
E06.4 Drug-induced thyroiditis
0.000 0.621 0.379
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.621 0.379
E06.1 Subacute thyroiditis
0.000 0.621 0.379
E06.0 Acute thyroiditis
0.000 0.621 0.379
E27.2 Addisonian crisis
0.000 0.624 0.376
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.625 0.375
E27.1 Primary adrenocortical insufficiency
0.000 0.630 0.370
E78.6 Lipoprotein deficiency
0.000 0.637 0.363
E78.3 Hyperchylomicronaemia
0.000 0.637 0.363
E88 Other metabolic disorders
0.000 0.637 0.363
E13.8 With unspecified complications
0.000 0.640 0.359
E13.7 With multiple complications
0.000 0.640 0.359
E13.6 With other specified complications
0.000 0.640 0.359
E13.5 With peripheral circulatory complications
0.000 0.640 0.359
E13.4 With neurological complications
0.000 0.640 0.359
E13.3 With ophthalmic complications
0.000 0.640 0.359
E13.2 With renal complications
0.000 0.640 0.359
E13.1 With ketoacidosis
0.000 0.640 0.359
E13.0 With coma
0.000 0.640 0.359
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.645 0.355
E11.8 With unspecified complications
0.000 0.647 0.352
E22 Hyperfunction of pituitary gland
0.000 0.650 0.350
E15 Nondiabetic hypoglycaemic coma
0.000 0.655 0.345
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.655 0.344
E32 Diseases of thymus
0.000 0.655 0.344
E31 Polyglandular dysfunction
0.000 0.655 0.344
E30 Disorders of puberty, not elsewhere classified
0.000 0.655 0.344
E06.9 Thyroiditis, unspecified
0.000 0.655 0.344
E24 Cushing's syndrome
0.000 0.659 0.341
E85 Amyloidosis
0.000 0.660 0.339
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.663 0.337
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.663 0.337
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.663 0.337
E74.2 Disorders of galactose metabolism
0.000 0.663 0.337
E74.1 Disorders of fructose metabolism
0.000 0.663 0.337
E74.0 Glycogen storage disease
0.000 0.663 0.337
E20 Hypoparathyroidism
0.000 0.664 0.336
E26.0 Primary hyperaldosteronism
0.000 0.668 0.332
E27.8 Other specified disorders of adrenal gland
0.000 0.668 0.332
E73.9 Lactose intolerance, unspecified
0.000 0.669 0.331
E03.8 Other specified hypothyroidism
0.000 0.672 0.327
E73.8 Other lactose intolerance
0.000 0.673 0.327
E73.1 Secondary lactase deficiency
0.000 0.673 0.327
E73.0 Congenital lactase deficiency
0.000 0.673 0.327
E40-E46 Malnutrition
0.000 0.673 0.326
E29.1 Testicular hypofunction
0.000 0.674 0.326
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.676 0.324
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.676 0.324
E70.3 Albinism
0.000 0.676 0.324
E70.2 Disorders of tyrosine metabolism
0.000 0.676 0.324
E70.1 Other hyperphenylalaninaemias
0.000 0.676 0.324
E70.0 Classical phenylketonuria
0.000 0.676 0.324
E71.3 Disorders of fatty-acid metabolism
0.000 0.676 0.324
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.676 0.324
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.676 0.324
E71.0 Maple-syrup-urine disease
0.000 0.676 0.324
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.676 0.324
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.676 0.324
E72.5 Disorders of glycine metabolism
0.000 0.676 0.324
E72.4 Disorders of ornithine metabolism
0.000 0.676 0.324
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.676 0.324
E72.2 Disorders of urea cycle metabolism
0.000 0.676 0.324
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.676 0.324
E72.0 Disorders of amino-acid transport
0.000 0.676 0.324
E75.6 Lipid storage disorder, unspecified
0.000 0.676 0.324
E75.5 Other lipid storage disorders
0.000 0.676 0.324
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.676 0.324
E75.3 Sphingolipidosis, unspecified
0.000 0.676 0.324
E75.2 Other sphingolipidosis
0.000 0.676 0.324
E75.1 Other gangliosidosis
0.000 0.676 0.324
E75.0 GM2 gangliosidosis
0.000 0.676 0.324
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.676 0.324
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.676 0.324
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.676 0.324
E76.2 Other mucopolysaccharidoses
0.000 0.676 0.324
E76.1 Mucopolysaccharidosis, type II
0.000 0.676 0.324
E76.0 Mucopolysaccharidosis, type I
0.000 0.676 0.324
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.676 0.324
E77.8 Other disorders of glycoprotein metabolism
0.000 0.676 0.324
E77.1 Defects in glycoprotein degradation
0.000 0.676 0.324
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.676 0.324
E84.9 Cystic fibrosis, unspecified
0.000 0.676 0.324
E84.8 Cystic fibrosis with other manifestations
0.000 0.676 0.324
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.676 0.324
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.676 0.324
E78.2 Mixed hyperlipidaemia
0.000 0.678 0.322
E27.5 Adrenomedullary hyperfunction
0.000 0.679 0.321
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.679 0.321
E27.0 Other adrenocortical overactivity
0.000 0.679 0.321
E12.9 Without complications
0.000 0.680 0.319
E12.8 With unspecified complications
0.000 0.680 0.319
E12.7 With multiple complications
0.000 0.680 0.319
E12.6 With other specified complications
0.000 0.680 0.319
E12.5 With peripheral circulatory complications
0.000 0.680 0.319
E12.4 With neurological complications
0.000 0.680 0.319
E12.3 With ophthalmic complications
0.000 0.680 0.319
E12.2 With renal complications
0.000 0.680 0.319
E12.1 With ketoacidosis
0.000 0.680 0.319
E12.0 With coma
0.000 0.680 0.319
E23 Hypofunction and other disorders of pituitary gland
0.000 0.685 0.315
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.686 0.314
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.686 0.314
E79.1 Lesch-Nyhan syndrome
0.000 0.686 0.314
E25 Adrenogenital disorders
0.000 0.688 0.312
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.689 0.311
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.689 0.311
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.689 0.311
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.689 0.311
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.689 0.311
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.689 0.311
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.689 0.311
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.689 0.311
E78.4 Other hyperlipidaemia
0.000 0.692 0.308
E16.2 Hypoglycaemia, unspecified
0.000 0.694 0.306
E34 Other endocrine disorders
0.000 0.694 0.306
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.697 0.303
E80.6 Other disorders of bilirubin metabolism
0.000 0.697 0.303
E80.5 Crigler-Najjar syndrome
0.000 0.697 0.303
E80.3 Defects of catalase and peroxydase
0.000 0.697 0.303
E80.2 Other porphyria
0.000 0.697 0.303
E80.1 Porphyria cutanea tarda
0.000 0.697 0.303
E80.0 Hereditary erythropoietic porphyria
0.000 0.697 0.303
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.700 0.300
E16.1 Other hypoglycaemia
0.000 0.701 0.298
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.702 0.298
E07 Other disorders of thyroid
0.000 0.711 0.289
E11.2 With renal complications
0.000 0.713 0.287
E03.5 Myxoedema coma
0.000 0.714 0.286
E03.4 Atrophy of thyroid (acquired)
0.000 0.714 0.286
E03.3 Postinfectious hypothyroidism
0.000 0.714 0.286
E03.1 Congenital hypothyroidism without goitre
0.000 0.714 0.286
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.714 0.286
E28 Ovarian dysfunction
0.000 0.714 0.286
E26.9 Hyperaldosteronism, unspecified
0.000 0.717 0.283
E26.8 Other hyperaldosteronism
0.000 0.717 0.283
E26.1 Secondary hyperaldosteronism
0.000 0.717 0.283
E89.2 Postprocedural hypoparathyroidism
0.000 0.717 0.283
E27.9 Disorder of adrenal gland, unspecified
0.000 0.717 0.283
E29.9 Testicular dysfunction, unspecified
0.000 0.720 0.280
E29.8 Other testicular dysfunction
0.000 0.720 0.280
E29.0 Testicular hyperfunction
0.000 0.720 0.280
E89.3 Postprocedural hypopituitarism
0.000 0.726 0.273
E80.4 Gilbert's syndrome
0.000 0.727 0.273
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.727 0.273
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.727 0.273
E16.4 Abnormal secretion of gastrin
0.000 0.727 0.273
E16.3 Increased secretion of glucagon
0.000 0.727 0.273
E23.2 Diabetes insipidus
0.000 0.729 0.271
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.731 0.269
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.731 0.269
E89.5 Postprocedural testicular hypofunction
0.000 0.731 0.269
E89.1 Postprocedural hypoinsulinaemia
0.000 0.731 0.269
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.731 0.268
E22.0 Acromegaly and pituitary gigantism
0.000 0.737 0.263
E88.9 Metabolic disorder, unspecified
0.000 0.739 0.260
E88.3 Tumour lysis syndrome
0.000 0.739 0.260
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.739 0.260
E89.4 Postprocedural ovarian failure
0.000 0.746 0.254
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.749 0.251
E22.8 Other hyperfunction of pituitary gland
0.000 0.749 0.251
E65-E68 Obesity and other hyperalimentation
0.000 0.752 0.248
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.752 0.248
E22.1 Hyperprolactinaemia
0.000 0.752 0.248
E30.9 Disorder of puberty, unspecified
0.000 0.753 0.247
E30.8 Other disorders of puberty
0.000 0.753 0.247
E30.1 Precocious puberty
0.000 0.753 0.247
E30.0 Delayed puberty
0.000 0.753 0.247
E31.9 Polyglandular dysfunction, unspecified
0.000 0.753 0.247
E31.8 Other polyglandular dysfunction
0.000 0.753 0.247
E31.1 Polyglandular hyperfunction
0.000 0.753 0.247
E31.0 Autoimmune polyglandular failure
0.000 0.753 0.247
E32.9 Disease of thymus, unspecified
0.000 0.753 0.247
E32.8 Other diseases of thymus
0.000 0.753 0.247
E32.1 Abscess of thymus
0.000 0.753 0.247
E32.0 Persistent hyperplasia of thymus
0.000 0.753 0.247
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.753 0.247
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.753 0.247
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.753 0.247
E24.8 Other Cushing's syndrome
0.000 0.755 0.244
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.755 0.244
E24.3 Ectopic ACTH syndrome
0.000 0.755 0.244
E24.2 Drug-induced Cushing's syndrome
0.000 0.755 0.244
E24.1 Nelson's syndrome
0.000 0.755 0.244
E24.0 Pituitary-dependent Cushing's disease
0.000 0.755 0.244
E85.8 Other amyloidosis
0.000 0.756 0.243
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.756 0.243
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.756 0.243
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.756 0.243
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.758 0.242
E88.2 Lipomatosis, not elsewhere classified
0.000 0.758 0.242
E20.8 Other hypoparathyroidism
0.000 0.759 0.241
E20.1 Pseudohypoparathyroidism
0.000 0.759 0.241
E20.0 Idiopathic hypoparathyroidism
0.000 0.759 0.241
E24.9 Cushing's syndrome, unspecified
0.000 0.759 0.241
E88.8 Other specified metabolic disorders
0.000 0.762 0.238
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.765 0.234
E45 Retarded development following protein-energy malnutrition
0.000 0.765 0.234
E43 Unspecified severe protein-energy malnutrition
0.000 0.765 0.234
E42 Marasmic kwashiorkor
0.000 0.765 0.234
E41 Nutritional marasmus
0.000 0.765 0.234
E40 Kwashiorkor
0.000 0.765 0.234
E85.3 Secondary systemic amyloidosis
0.000 0.767 0.233
E20.9 Hypoparathyroidism, unspecified
0.000 0.767 0.233
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.769 0.230
E14 Unspecified diabetes mellitus
0.000 0.770 0.229
E23.6 Other disorders of pituitary gland
0.000 0.771 0.229
E85.9 Amyloidosis, unspecified
0.000 0.774 0.226
E34.8 Other specified endocrine disorders
0.000 0.774 0.226
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.774 0.226
E23.1 Drug-induced hypopituitarism
0.000 0.774 0.226
E25.9 Adrenogenital disorder, unspecified
0.000 0.776 0.224
E25.8 Other adrenogenital disorders
0.000 0.776 0.224
E50-E64 Other nutritional deficiencies
0.000 0.780 0.219
E34.5 Androgen resistance syndrome
0.000 0.781 0.219
E34.4 Constitutional tall stature
0.000 0.781 0.219
E34.3 Short stature, not elsewhere classified
0.000 0.781 0.219
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.781 0.219
E34.1 Other hypersecretion of intestinal hormones
0.000 0.781 0.219
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.781 0.219
E34.0 Carcinoid syndrome
0.000 0.782 0.218
E07.1 Dyshormogenetic goitre
0.000 0.793 0.207
E07.0 Hypersecretion of calcitonin
0.000 0.793 0.207
E28.9 Ovarian dysfunction, unspecified
0.000 0.795 0.205
E28.8 Other ovarian dysfunction
0.000 0.795 0.205
E28.1 Androgen excess
0.000 0.795 0.205
E28.0 Oestrogen excess
0.000 0.795 0.205
E87.2 Acidosis
0.000 0.798 0.202
E23.7 Disorder of pituitary gland, unspecified
0.000 0.801 0.198
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.808 0.192
E89.0 Postprocedural hypothyroidism
0.000 0.815 0.185
E28.3 Primary ovarian failure
0.000 0.815 0.185
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.817 0.183
E86 Volume depletion
0.000 0.819 0.181
E07.8 Other specified disorders of thyroid
0.000 0.819 0.181
E85.4 Organ-limited amyloidosis
0.001 0.819 0.181
E67 Other hyperalimentation
0.000 0.822 0.178
E68 Sequelae of hyperalimentation
0.000 0.822 0.178
E28.2 Polycystic ovarian syndrome
0.000 0.826 0.174
E34.9 Endocrine disorder, unspecified
0.000 0.829 0.171
E44.1 Mild protein-energy malnutrition
0.000 0.832 0.168
E44.0 Moderate protein-energy malnutrition
0.000 0.832 0.168
E14.3 With ophthalmic complications
0.000 0.833 0.167
E87.3 Alkalosis
0.000 0.834 0.166
E14.7 With multiple complications
0.000 0.835 0.165
E14.5 With peripheral circulatory complications
0.000 0.835 0.165
E14.2 Withrenal complications
0.000 0.835 0.165
E14.1 With ketoacidosis
0.000 0.835 0.165
E14.0 With coma
0.000 0.835 0.165
E11.9 Without complications
0.000 0.836 0.164
E14.8 With unspecified complications
0.000 0.837 0.163
E14.4 With neurological complications
0.000 0.842 0.158
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.842 0.157
E63 Other nutritional deficiencies
0.000 0.842 0.157
E56 Other vitamin deficiencies
0.000 0.842 0.157
E51 Thiamine deficiency
0.000 0.842 0.157
E50 Vitamin A deficiency
0.000 0.842 0.157
E60 Dietary zinc deficiency
0.000 0.842 0.157
E59 Dietary selenium deficiency
0.000 0.842 0.157
E58 Dietary calcium deficiency
0.000 0.842 0.157
E54 Ascorbic acid deficiency
0.000 0.842 0.157
E52 Niacin deficiency [pellagra]
0.000 0.842 0.157
E87.4 Mixed disorder of acid-base balance
0.000 0.843 0.157
E14.6 With other specified complications
0.000 0.849 0.150
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.854 0.146
E04.1 Non-toxic single thyroid nodule
0.000 0.857 0.143
E87.5 Hyperkalaemia
0.000 0.857 0.143
E03.9 Hypothyroidism, unspecified
0.000 0.864 0.136
E65 Localised adiposity
0.000 0.865 0.134
E87.6 Hypokalaemia
0.000 0.867 0.133
E53 Deficiency of other B group vitamins
0.000 0.871 0.129
E67.8 Other specified hyperalimentation
0.000 0.872 0.128
E67.3 Hypervitaminosis D
0.000 0.872 0.128
E67.2 Megavitamin-B6 syndrome
0.000 0.872 0.128
E67.1 Hypercarotenaemia
0.000 0.872 0.128
E67.0 Hypervitaminosis A
0.000 0.872 0.128
E23.0 Hypopituitarism
0.000 0.876 0.124
E07.9 Disorder of thyroid, unspecified
0.000 0.883 0.117
E55 Vitamin D deficiency
0.000 0.884 0.115
E46 Unspecified protein-energy malnutrition
0.001 0.884 0.115
E50.9 Vitamin A deficiency, unspecified
0.000 0.887 0.113
E50.8 Other manifestations of vitamin A deficiency
0.000 0.887 0.113
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.887 0.113
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.887 0.113
E50.5 Vitamin A deficiency with night blindness
0.000 0.887 0.113
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.887 0.113
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.887 0.113
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.887 0.113
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.887 0.113
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.887 0.113
E51.9 Thiamine deficiency, unspecified
0.000 0.887 0.113
E51.8 Other manifestations of thiamine deficiency
0.000 0.887 0.113
E51.2 Wernicke's encephalopathy
0.000 0.887 0.113
E51.1 Beriberi
0.000 0.887 0.113
E56.9 Vitamin deficiency, unspecified
0.000 0.887 0.113
E56.8 Deficiency of other vitamins
0.000 0.887 0.113
E56.1 Deficiency of vitamin K
0.000 0.887 0.113
E56.0 Deficiency of vitamin E
0.000 0.887 0.113
E63.9 Nutritional deficiency, unspecified
0.000 0.887 0.113
E63.8 Other specified nutritional deficiencies
0.000 0.887 0.113
E63.1 Imbalance of constituents of food intake
0.000 0.887 0.113
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.887 0.113
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.887 0.113
E64.8 Sequelae of other nutritional deficiencies
0.000 0.887 0.113
E64.3 Sequelae of rickets
0.000 0.887 0.113
E64.2 Sequelae of vitamin C deficiency
0.000 0.887 0.113
E64.1 Sequelae of vitamin A deficiency
0.000 0.887 0.113
E64.0 Sequelae of protein-energy malnutrition
0.000 0.887 0.113
N13.8 Other obstructive and reflux uropathy
0.000 0.895 0.105
N13 Obstructive and reflux uropathy
0.000 0.895 0.105
E21.4 Other specified disorders of parathyroid gland
0.000 0.895 0.105
E21.2 Other hyperparathyroidism
0.000 0.895 0.105
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.896 0.104
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.000 0.897 0.103
N13.5 Kinking and stricture of ureter without hydronephrosis
0.000 0.897 0.103
E61 Deficiency of other nutrient elements
0.001 0.898 0.101
E78.5 Hyperlipidaemia, unspecified
0.000 0.899 0.101
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.905 0.094
E53.1 Pyridoxine deficiency
0.000 0.907 0.093
E53.0 Riboflavin deficiency
0.000 0.907 0.093
N13.9 Obstructive and reflux uropathy, unspecified
0.000 0.909 0.091
E53.8 Deficiency of other specified B group vitamins
0.000 0.910 0.090
N13.6 Pyonephrosis
0.000 0.913 0.087
E87.0 Hyperosmolality and hypernatraemia
0.000 0.915 0.085
E55.0 Rickets, active
0.000 0.917 0.083
E66 Obesity
0.000 0.917 0.083
N13.7 Vesicoureteral-reflux-associated uropathy
0.000 0.924 0.075
E61.9 Deficiency of nutrient element, unspecified
0.001 0.926 0.073
E61.8 Deficiency of other specified nutrient elements
0.001 0.926 0.073
E61.7 Deficiency of multiple nutrient elements
0.001 0.926 0.073
E61.6 Vanadium deficiency
0.001 0.926 0.073
E61.5 Molybdenum deficiency
0.001 0.926 0.073
E61.4 Chromium deficiency
0.001 0.926 0.073
E61.3 Manganese deficiency
0.001 0.926 0.073
E61.0 Copper deficiency
0.001 0.926 0.073
E53.9 Vitamin B deficiency, unspecified
0.001 0.931 0.069
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.000 0.931 0.069
E61.2 Magnesium deficiency
0.001 0.932 0.067
N13.4 Hydroureter
0.000 0.932 0.068
E21.3 Hyperparathyroidism, unspecified
0.000 0.938 0.062
E66.1 Drug-induced obesity
0.000 0.940 0.060
E66.8 Other obesity
0.000 0.941 0.059
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.942 0.058
E87.7 Fluid overload
0.000 0.947 0.053
E21.0 Primary hyperparathyroidism
0.000 0.948 0.052
N13.3 Other and unspecified hydronephrosis
0.000 0.949 0.051
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.000 0.950 0.050
O03 Spontaneous abortion
0.048 0.952 0.000
O03.9 Complete or unspecified, without complication
0.047 0.953 0.000
O03.4 Incomplete, without complication
0.046 0.954 0.000
E66.0 Obesity due to excess calories
0.000 0.955 0.045
O00-O08 Pregnancy with abortive outcome
0.042 0.958 0.000
E55.9 Vitamin D deficiency, unspecified
0.001 0.959 0.041
O03.3 Incomplete, with other and unspecified complications
0.039 0.961 0.000
O02 Other abnormal products of conception
0.039 0.961 0.000
D37.5 Rectum
0.000 0.963 0.037
O02.1 Missed abortion
0.036 0.964 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.034 0.966 0.000
O03.7 Complete or unspecified, complicated by embolism
0.034 0.966 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.034 0.966 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.034 0.966 0.000
O03.2 Incomplete, complicated by embolism
0.034 0.966 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.034 0.966 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.034 0.966 0.000
O21 Excessive vomiting in pregnancy
0.034 0.966 0.000
O21.0 Mild hyperemesis gravidarum
0.033 0.967 0.000
O70.0 First degree perineal laceration during delivery
0.033 0.967 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.033 0.967 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.032 0.968 0.000
E61.1 Iron deficiency
0.001 0.969 0.030
O85-O92 Complications predominantly related to the puerperium
0.031 0.969 0.000
O00 Ectopic pregnancy
0.031 0.969 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.030 0.970 0.000
O07 Failed attempted abortion
0.030 0.970 0.000
O06 Unspecified abortion
0.030 0.970 0.000
O05 Other abortion
0.030 0.970 0.000
O01 Hydatidiform mole
0.030 0.970 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.030 0.970 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.030 0.970 0.000
O21.9 Vomiting of pregnancy, unspecified
0.029 0.971 0.000
O70 Perineal laceration during delivery
0.029 0.971 0.000
O60-O75 Complications of labour and delivery
0.028 0.972 0.000
O02.9 Abnormal product of conception, unspecified
0.028 0.972 0.000
O02.8 Other specified abnormal products of conception
0.028 0.972 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.000 0.972 0.027
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.027 0.973 0.000
O23 Infections of genito-urinary tract in pregnancy
0.027 0.973 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.027 0.973 0.000
O00.9 Ectopic pregnancy, unspecified
0.027 0.973 0.000
O86 Other puerperal infections
0.027 0.973 0.000
O80-O84 Delivery
0.026 0.974 0.000
O90 Complications of the puerperium, not elsewhere classified
0.025 0.975 0.000
O21.2 Late vomiting of pregnancy
0.025 0.975 0.000
D37.7 Other digestive organs
0.000 0.975 0.025
O21.8 Other vomiting complicating pregnancy
0.025 0.975 0.000
O14.9 Preeclampsia, unspecified
0.025 0.975 0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance
0.025 0.975 0.000
D37.0 Lip, oral cavity and pharynx
0.000 0.975 0.025
O85 Puerperal sepsis
0.024 0.976 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.024 0.976 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.024 0.976 0.000
O66 Other obstructed labour
0.024 0.976 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.023 0.976 0.000
D37.1 Stomach
0.000 0.977 0.023
O70.2 Third degree perineal laceration during delivery
0.023 0.977 0.000
O29 Complications of anaesthesia during pregnancy
0.023 0.977 0.000
O22 Venous complications in pregnancy
0.023 0.977 0.000
O25 Malnutrition in pregnancy
0.023 0.977 0.000
O63 Long labour
0.023 0.977 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.023 0.977 0.000
O61 Failed induction of labour
0.023 0.977 0.000
O14.1 Severe preeclampsia
0.023 0.977 0.000
O91 Infections of breast associated with childbirth
0.022 0.977 0.000
O89 Complications of anaesthesia during the puerperium
0.022 0.977 0.000
O88 Obstetric embolism
0.022 0.977 0.000
O71 Other obstetric trauma
0.023 0.977 0.000
D37.6 Liver, gallbladder and bile ducts
0.000 0.977 0.023
O86.2 Urinary tract infection following delivery
0.022 0.978 0.000
O00.8 Other ectopic pregnancy
0.022 0.978 0.000
O00.2 Ovarian pregnancy
0.022 0.978 0.000
O00.0 Abdominal pregnancy
0.022 0.978 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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