TreeWAS – Variant ID: rs10498792

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.970	0.030	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.969	0.031	0.000
I25.1 Atherosclerotic heart disease	0.967	0.033	0.000
I25.2 Old myocardial infarction	0.897	0.103	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.878	0.122	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.863	0.137	0.000
I25.3 Aneurysm of heart	0.837	0.163	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.780	0.220	0.000
I25.6 Silent myocardial ischaemia	0.696	0.304	0.000
I25.4 Coronary artery aneurysm	0.625	0.375	0.000
I25.5 Ischaemic cardiomyopathy	0.596	0.403	0.000
D22 Melanocytic naevi	0.562	0.438	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.488	0.512	0.000
D22.9 Melanocytic naevi, unspecified	0.451	0.549	0.000
D22.0 Melanocytic naevi of lip	0.451	0.549	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.427	0.573	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.422	0.578	0.000
D22.5 Melanocytic naevi of trunk	0.368	0.632	0.000
I20-I25 Ischaemic heart diseases	0.351	0.649	0.000
I20 Angina pectoris	0.316	0.684	0.000
D22.4 Melanocytic naevi of scalp and neck	0.304	0.696	0.000
D10-D36 Benign neoplasms	0.292	0.708	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.289	0.711	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.286	0.714	0.000
I21 Acute myocardial infarction	0.284	0.716	0.000
I20.1 Angina pectoris with documented spasm	0.280	0.720	0.000
D28.0 Vulva	0.277	0.723	0.000
D13.1 Stomach	0.274	0.726	0.000
I20.8 Other forms of angina pectoris	0.270	0.730	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.269	0.731	0.000
D13.6 Pancreas	0.256	0.744	0.000
D36 Benign neoplasm of other and unspecified sites	0.251	0.749	0.000
I21.4 Acute subendocardial myocardial infarction	0.251	0.749	0.000
I20.0 Unstable angina	0.251	0.749	0.000
D28.1 Vagina	0.248	0.751	0.000
D11 Benign neoplasm of major salivary glands	0.245	0.755	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.241	0.759	0.000
D13.3 Other and unspecified parts of small intestine	0.238	0.762	0.000
D23.1 Skin of eyelid, including canthus	0.238	0.762	0.000
D23 Other benign neoplasms of skin	0.237	0.763	0.000
I23 Certain current complications following acute myocardial infarction	0.236	0.764	0.000
D13.4 Liver	0.235	0.765	0.000
D26 Other benign neoplasms of uterus	0.235	0.765	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.233	0.767	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.225	0.775	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.219	0.781	0.000
D29 Benign neoplasm of male genital organs	0.217	0.783	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.217	0.783	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.209	0.791	0.000
D19 Benign neoplasm of mesothelial tissue	0.209	0.791	0.000
D13.9 Ill-defined sites within the digestive system	0.207	0.792	0.000
D13.7 Endocrine pancreas	0.207	0.792	0.000
D36.0 Lymph nodes	0.207	0.793	0.000
D11.0 Parotid gland	0.207	0.793	0.000
D28.9 Female genital organ, unspecified	0.205	0.794	0.000
D28.7 Other specified female genital organs	0.205	0.794	0.000
D13.2 Duodenum	0.205	0.795	0.000
D28.2 Uterine tubes and ligaments	0.204	0.796	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.204	0.796	0.000
D24 Benign neoplasm of breast	0.201	0.799	0.000
D26.1 Corpus uteri	0.200	0.800	0.000
D27 Benign neoplasm of ovary	0.200	0.800	0.000
D13.0 Oesophagus	0.198	0.802	0.000
D13.5 Extrahepatic bile ducts	0.198	0.802	0.000
D16 Benign neoplasm of bone and articular cartilage	0.195	0.805	0.000
D23.7 Skin of lower limb, including hip	0.192	0.808	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.191	0.809	0.000
D11.9 Major salivary gland, unspecified	0.191	0.809	0.000
D15.0 Thymus	0.189	0.811	0.000
D14.3 Bronchus and lung	0.189	0.811	0.000
D23.3 Skin of other and unspecified parts of face	0.184	0.816	0.000
D10 Benign neoplasm of mouth and pharynx	0.183	0.817	0.000
D36.9 Benign neoplasm of unspecified site	0.180	0.820	0.000
I21.9 Acute myocardial infarction, unspecified	0.176	0.824	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.175	0.825	0.000
D21.9 Connective and other soft tissue, unspecified	0.173	0.827	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.173	0.827	0.000
D21.4 Connective and other soft tissue of abdomen	0.173	0.827	0.000
D21.3 Connective and other soft tissue of thorax	0.173	0.827	0.000
D21.5 Connective and other soft tissue of pelvis	0.172	0.828	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.171	0.829	0.000
D16.9 Bone and articular cartilage, unspecified	0.171	0.829	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.169	0.831	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.169	0.831	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.169	0.831	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.169	0.831	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.169	0.831	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.169	0.831	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.169	0.831	0.000
D26.9 Uterus, unspecified	0.169	0.831	0.000
D15.1 Heart	0.169	0.831	0.000
D26.7 Other parts of uterus	0.169	0.831	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.168	0.832	0.000
D15.9 Intrathoracic organ, unspecified	0.167	0.833	0.000
D15.7 Other specified intrathoracic organs	0.167	0.833	0.000
D15.2 Mediastinum	0.167	0.833	0.000
D31 Benign neoplasm of eye and adnexa	0.166	0.834	0.000
D11.7 Other major salivary glands	0.165	0.835	0.000
D32 Benign neoplasm of meninges	0.162	0.838	0.000
D14.4 Respiratory system, unspecified	0.161	0.839	0.000
D14.2 Trachea	0.161	0.839	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.160	0.839	0.000
D30 Benign neoplasm of urinary organs	0.160	0.840	0.000
D29.1 Prostate	0.160	0.840	0.000
D29.0 Penis	0.159	0.841	0.000
D26.0 Cervix uteri	0.157	0.843	0.000
D29.4 Scrotum	0.157	0.843	0.000
D29.9 Male genital organ, unspecified	0.156	0.844	0.000
D29.7 Other male genital organs	0.156	0.844	0.000
D29.3 Epididymis	0.156	0.844	0.000
D29.2 Testis	0.156	0.844	0.000
D36.7 Other specified sites	0.156	0.844	0.000
I23.8 Other current complications following acute myocardial infarction	0.153	0.847	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.151	0.848	0.000
D14.1 Larynx	0.151	0.849	0.000
I20.9 Angina pectoris, unspecified	0.150	0.850	0.000
D19.9 Mesothelial tissue, unspecified	0.150	0.850	0.000
D19.7 Mesothelial tissue of other sites	0.150	0.850	0.000
D19.1 Mesothelial tissue of peritoneum	0.150	0.850	0.000
D19.0 Mesothelial tissue of pleura	0.150	0.850	0.000
D20.1 Peritoneum	0.150	0.850	0.000
D20.0 Retroperitoneum	0.150	0.850	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.149	0.851	0.000
D23.9 Skin, unspecified	0.147	0.853	0.000
D10.9 Pharynx, unspecified	0.146	0.854	0.000
D16.5 Lower jaw bone	0.145	0.855	0.000
D16.0 Scapula and long bones of upper limb	0.144	0.856	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.140	0.860	0.000
D16.7 Ribs, sternum and clavicle	0.140	0.860	0.000
D16.6 Vertebral column	0.140	0.860	0.000
D18 Haemangioma and lymphangioma, any site	0.137	0.863	0.000
I24 Other acute ischaemic heart diseases	0.137	0.863	0.000
D10.3 Other and unspecified parts of mouth	0.133	0.866	0.000
D23.2 Skin of ear and external auricular canal	0.132	0.868	0.000
D10.7 Hypopharynx	0.131	0.869	0.000
D10.6 Nasopharynx	0.131	0.869	0.000
D10.5 Other parts of oropharynx	0.131	0.869	0.000
D10.4 Tonsil	0.131	0.869	0.000
D10.2 Floor of mouth	0.131	0.869	0.000
D16.2 Long bones of lower limb	0.130	0.869	0.000
D16.3 Short bones of lower limb	0.128	0.872	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.126	0.873	0.000
D32.9 Meninges, unspecified	0.125	0.875	0.000
D35.9 Endocrine gland, unspecified	0.123	0.877	0.000
D35.8 Pluriglandular involvement	0.123	0.877	0.000
D35.7 Other specified endocrine glands	0.123	0.877	0.000
D35.6 Aortic body and other paraganglia	0.123	0.877	0.000
D35.5 Carotid body	0.123	0.877	0.000
D35.4 Pineal gland	0.123	0.877	0.000
D35.3 Craniopharyngeal duct	0.123	0.877	0.000
D35.0 Adrenal gland	0.122	0.877	0.000
D35.1 Parathyroid gland	0.122	0.878	0.000
D23.6 Skin of upper limb, including shoulder	0.120	0.880	0.000
D31.9 Eye, unspecified	0.119	0.880	0.000
D31.6 Orbit, unspecified	0.119	0.880	0.000
D31.5 Lachrymal gland and duct	0.119	0.880	0.000
D31.4 Ciliary body	0.119	0.880	0.000
D31.2 Retina	0.119	0.880	0.000
D31.1 Cornea	0.119	0.880	0.000
D23.0 Skin of lip	0.119	0.881	0.000
D30.9 Urinary organ, unspecified	0.115	0.885	0.000
D30.7 Other urinary organs	0.115	0.885	0.000
D30.4 Urethra	0.115	0.885	0.000
D30.2 Ureter	0.115	0.885	0.000
D30.1 Renal pelvis	0.115	0.885	0.000
D16.4 Bones of skull and face	0.115	0.885	0.000
D10.0 Lip	0.107	0.892	0.000
D33.9 Central nervous system, unspecified	0.107	0.893	0.000
D33.7 Other specified parts of central nervous system	0.107	0.893	0.000
D33.4 Spinal cord	0.107	0.893	0.000
D33.1 Brain, infratentorial	0.107	0.893	0.000
D33.0 Brain, supratentorial	0.107	0.893	0.000
I22 Subsequent myocardial infarction	0.106	0.893	0.000
D16.1 Short bones of upper limb	0.105	0.894	0.000
D10.1 Tongue	0.104	0.895	0.000
D31.3 Choroid	0.104	0.896	0.000
D32.1 Spinal meninges	0.103	0.896	0.000
D30.0 Kidney	0.102	0.897	0.000
D23.4 Skin of scalp and neck	0.102	0.898	0.000
I24.1 Dressler's syndrome	0.101	0.899	0.000
D31.0 Conjunctiva	0.099	0.901	0.000
D33.2 Brain, unspecified	0.092	0.908	0.000
D18.1 Lymphangioma, any site	0.088	0.912	0.000
D23.5 Skin of trunk	0.088	0.912	0.000
D30.3 Bladder	0.087	0.913	0.000
D35.2 Pituitary gland	0.087	0.913	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.086	0.914	0.000
I22.8 Subsequent myocardial infarction of other sites	0.081	0.919	0.000
D34 Benign neoplasm of thyroid gland	0.077	0.923	0.001
I21.1 Acute transmural myocardial infarction of inferior wall	0.074	0.926	0.000
D33.3 Cranial nerves	0.074	0.926	0.000
D32.0 Cerebral meninges	0.072	0.928	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.071	0.929	0.000
I24.8 Other forms of acute ischaemic heart disease	0.063	0.937	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.062	0.938	0.000
I73.9 Peripheral vascular disease, unspecified	0.061	0.939	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.057	0.942	0.001
I70-I79 Diseases of arteries, arterioles and capillaries	0.056	0.944	0.000
I73 Other peripheral vascular diseases	0.055	0.945	0.000
I77 Other disorders of arteries and arterioles	0.053	0.947	0.000
Chapter IX Diseases of the circulatory system	0.053	0.947	0.000
D18.0 Haemangioma, any site	0.050	0.950	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.047	0.953	0.000
I77.1 Stricture of artery	0.046	0.954	0.000
I72 Other aneurysm	0.046	0.954	0.000
I10-I15 Hypertensive diseases	0.046	0.954	0.000
I78 Diseases of capillaries	0.045	0.955	0.000
I70 Atherosclerosis	0.045	0.955	0.000
I72.4 Aneurysm of artery of lower extremity	0.044	0.956	0.000
I10 Essential (primary) hypertension	0.043	0.957	0.000
I77.0 Arteriovenous fistula, acquired	0.042	0.958	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.040	0.960	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.962	0.038
I77.5 Necrosis of artery	0.038	0.962	0.000
I77.4 Coeliac artery compression syndrome	0.038	0.962	0.000
I77.3 Arterial fibromuscular dysplasia	0.038	0.962	0.000
I77.2 Rupture of artery	0.038	0.962	0.000
I00-I02 Acute rheumatic fever	0.038	0.962	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.038	0.962	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.037	0.963	0.000
I77.8 Other specified disorders of arteries and arterioles	0.036	0.964	0.000
I74 Arterial embolism and thrombosis	0.036	0.964	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.036	0.964	0.000
I78.8 Other diseases of capillaries	0.035	0.965	0.000
I73.8 Other specified peripheral vascular diseases	0.035	0.965	0.000
I11 Hypertensive heart disease	0.035	0.965	0.000
I72.9 Aneurysm of unspecified site	0.033	0.967	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.033	0.967	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.033	0.967	0.000
I72.2 Aneurysm of renal artery	0.033	0.967	0.000
I72.1 Aneurysm of artery of upper extremity	0.033	0.967	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.033	0.967	0.000
I77.6 Arteritis, unspecified	0.033	0.967	0.000
I13 Hypertensive heart and renal disease	0.033	0.967	0.000
I72.3 Aneurysm of iliac artery	0.033	0.967	0.000
I70.9 Generalised and unspecified atherosclerosis	0.032	0.968	0.000
I70.8 Atherosclerosis of other arteries	0.032	0.968	0.000
I70.1 Atherosclerosis of renal artery	0.032	0.968	0.000
I78.9 Disease of capillaries, unspecified	0.032	0.968	0.000
I70.0 Atherosclerosis of aorta	0.032	0.968	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.032	0.968	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.031	0.969	0.000
I72.8 Aneurysm of other specified arteries	0.031	0.969	0.000
I15 Secondary hypertension	0.029	0.970	0.000
D25 Leiomyoma of uterus	0.029	0.971	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.028	0.972	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.028	0.972	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.028	0.972	0.000
I02 Rheumatic chorea	0.027	0.973	0.000
I01 Rheumatic fever with heart involvement	0.027	0.973	0.000
I00 Rheumatic fever without mention of heart involvement	0.027	0.973	0.000
I78.1 Naevus, nonneoplastic	0.027	0.973	0.000
I74.8 Embolism and thrombosis of other arteries	0.027	0.973	0.000
I12 Hypertensive renal disease	0.026	0.974	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.026	0.974	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.026	0.974	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.026	0.974	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.026	0.974	0.000
I79.1 Aortitis in diseases classified elsewhere	0.026	0.974	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.026	0.974	0.000
I60-I69 Cerebrovascular diseases	0.024	0.976	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.024	0.976	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.024	0.976	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.024	0.976	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.024	0.976	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.024	0.976	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.023	0.976	0.001
I61 Intracerebral haemorrhage	0.024	0.976	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.023	0.977	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.023	0.977	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.023	0.977	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.023	0.977	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.023	0.977	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.023	0.977	0.000
I05-I09 Chronic rheumatic heart diseases	0.023	0.977	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.023	0.977	0.000
I71 Aortic aneurysm and dissection	0.023	0.977	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.022	0.977	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.022	0.977	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.022	0.978	0.000
I15.9 Seconday hypertension, unspecified	0.022	0.978	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.021	0.978	0.000
I15.8 Other secondary hypertension	0.021	0.978	0.000
I15.2 Hypertension secondary to endocrine disorders	0.021	0.978	0.000
I15.0 Renovascular hypertension	0.021	0.978	0.000
I72.0 Aneurysm of carotid artery	0.021	0.979	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.021	0.979	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.021	0.979	0.000
D17 Benign lipomatous neoplasm	0.021	0.979	0.000
I12.9 Hypertensive renal disease without renal failure	0.020	0.980	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.020	0.980	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.020	0.980	0.000
I01.8 Other acute rheumatic heart disease	0.020	0.980	0.000
I01.2 Acute rheumatic myocarditis	0.020	0.980	0.000
I01.1 Acute rheumatic endocarditis	0.020	0.980	0.000
I01.0 Acute rheumatic pericarditis	0.020	0.980	0.000
I02.9 Rheumatic chorea without heart involvement	0.020	0.980	0.000
I02.0 Rheumatic chorea with heart involvement	0.020	0.980	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.020	0.980	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.020	0.980	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.019	0.981	0.000
I95 Hypotension	0.019	0.981	0.000
I60 Subarachnoid haemorrhage	0.019	0.981	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.019	0.981	0.000
K90.0 Coeliac disease	0.000	0.982	0.018
I68 Cerebrovascular disorders in diseases classified elsewhere	0.018	0.982	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.018	0.982	0.000
I05 Rheumatic mitral valve diseases	0.018	0.982	0.000
I15.1 Hypertension secondary to other renal disorders	0.017	0.982	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.018	0.982	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.017	0.982	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.017	0.983	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.017	0.983	0.000
I71.0 Dissection of aorta [any part]	0.017	0.983	0.000
I06 Rheumatic aortic valve diseases	0.017	0.983	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.017	0.983	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.017	0.983	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.017	0.983	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.017	0.983	0.000
I95.2 Hypotension due to drugs	0.017	0.983	0.000
I05.9 Mitral valve disease, unspecified	0.017	0.983	0.000
I28 Other diseases of pulmonary vessels	0.016	0.984	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.016	0.984	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.016	0.984	0.000
I99 Other and unspecified disorders of circulatory system	0.016	0.984	0.000
I09 Other rheumatic heart diseases	0.015	0.985	0.000
Z95.1 Presence of aortocoronary bypass graft	0.015	0.985	0.000
I07 Rheumatic tricuspid valve diseases	0.015	0.985	0.000
I73.0 Raynaud's syndrome	0.015	0.985	0.000
I62 Other nontraumatic intracranial haemorrhage	0.015	0.985	0.000
I67 Other cerebrovascular diseases	0.015	0.985	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.015	0.985	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.015	0.985	0.000
U80.1 Methicillin resistant agent	0.000	0.985	0.015
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.015	0.985	0.000
I95.0 Idiopathic hypotension	0.015	0.985	0.000
M16.0 Primary coxarthrosis, bilateral	0.000	0.985	0.015
I61.8 Other intracerebral haemorrhage	0.014	0.986	0.000
I95.9 Hypotension, unspecified	0.014	0.986	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.014	0.986	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.014	0.986	0.000
K50.9 Crohn's disease, unspecified	0.000	0.986	0.014
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.014	0.986	0.000
D25.2 Subserosal leiomyoma of uterus	0.014	0.986	0.000
K50.0 Crohn's disease of small intestine	0.000	0.986	0.014
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.014	0.986	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.014	0.986	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.014	0.986	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.014	0.986	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.014	0.986	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.014	0.986	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.014	0.986	0.000
I65.1 Occlusion and stenosis of basilar artery	0.014	0.986	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.013	0.986	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.986	0.014
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.987	0.013
I67.2 Cerebral atherosclerosis	0.013	0.987	0.000
I95.8 Other hypotension	0.013	0.987	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.013	0.987	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.013	0.987	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.013	0.987	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.013	0.987	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.013	0.987	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.013	0.987	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.013	0.987	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.013	0.987	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.013	0.987	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.013	0.987	0.000
I68.0 Cerebral amyloid angiopathy	0.013	0.987	0.000
I05.8 Other mitral valve diseases	0.013	0.987	0.000
I65.2 Occlusion and stenosis of carotid artery	0.013	0.987	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.987	0.013
D25.9 Leiomyoma of uterus, unspecified	0.013	0.987	0.000
I69 Sequelae of cerebrovascular disease	0.013	0.987	0.000
J34.2 Deviated nasal septum	0.000	0.988	0.012
I28.8 Other specified diseases of pulmonary vessels	0.012	0.988	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.012	0.988	0.000
I06.8 Other rheumatic aortic valve diseases	0.012	0.988	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.012	0.988	0.000
I06.1 Rheumatic aortic insufficiency	0.012	0.988	0.000
I06.0 Rheumatic aortic stenosis	0.012	0.988	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.012	0.988	0.000
I28.1 Aneurysm of pulmonary artery	0.012	0.988	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.012	0.988	0.000
I05.0 Mitral stenosis	0.012	0.988	0.000
I74.5 Embolism and thrombosis of iliac artery	0.011	0.988	0.001
K90 Intestinal malabsorption	0.000	0.988	0.012
I67.9 Cerebrovascular disease, unspecified	0.012	0.988	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.012	0.988	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.011	0.989	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.011	0.989	0.000
I09.8 Other specified rheumatic heart diseases	0.011	0.989	0.000
I09.2 Chronic rheumatic pericarditis	0.011	0.989	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.011	0.989	0.000
I09.0 Rheumatic myocarditis	0.011	0.989	0.000
I07.9 Tricuspid valve disease, unspecified	0.011	0.989	0.000
I07.8 Other tricuspid valve diseases	0.011	0.989	0.000
I07.2 Tricuspid stenosis with insufficiency	0.011	0.989	0.000
I07.0 Tricuspid stenosis	0.011	0.989	0.000
K50.8 Other Crohn's disease	0.000	0.989	0.011
K35.9 Acute appendicitis, unspecified	0.000	0.989	0.011
I62.1 Nontraumatic extradural haemorrhage	0.011	0.989	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.011	0.989	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.011	0.989	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.011	0.989	0.000
I67.5 Moyamoya disease	0.011	0.989	0.000
I67.4 Hypertensive encephalopathy	0.011	0.989	0.000
I67.3 Progressive vascular leukoencephalopathy	0.011	0.989	0.000
F20.9 Schizophrenia, unspecified	0.011	0.989	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.011	0.989	0.000
I05.2 Mitral stenosis with insufficiency	0.011	0.989	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.011	0.989	0.000
I27 Other pulmonary heart diseases	0.011	0.989	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.989	0.010
I05.1 Rheumatic mitral insufficiency	0.010	0.990	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.010	0.990	0.000
U80.0 Penicillin resistant agent	0.000	0.990	0.010
I63 Cerebral infarction	0.010	0.990	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.010	0.990	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
I98.0 Cardiovascular syphilis	0.010	0.990	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.010	0.990	0.000
I09.9 Rheumatic heart disease, unspecified	0.010	0.990	0.000
D25.0 Submucous leiomyoma of uterus	0.010	0.990	0.000
I07.1 Tricuspid insufficiency	0.010	0.990	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.010	0.990	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.010	0.990	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.009	0.990	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.009	0.991	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.009	0.991	0.000
I60.8 Other subarachnoid haemorrhage	0.009	0.991	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.009	0.991	0.000
I12.0 Hypertensive renal disease with renal failure	0.009	0.991	0.000
I26 Pulmonary embolism	0.009	0.991	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.009	0.991	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.009	0.991	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.009	0.991	0.000
K90.8 Other intestinal malabsorption	0.000	0.991	0.009
K90.3 Pancreatic steatorrhoea	0.000	0.991	0.009
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.991	0.009
K90.1 Tropical sprue	0.000	0.991	0.009
I63.8 Other cerebral infarction	0.009	0.991	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.008	0.991	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.008	0.992	0.000
I97.0 Postcardiotomy syndrome	0.008	0.992	0.000
I67.1 Cerebral aneurysm, nonruptured	0.008	0.992	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.008	0.992	0.000
I95.1 Orthostatic hypotension	0.008	0.992	0.000
I27.1 Kyphoscoliotic heart disease	0.008	0.992	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.008	0.992	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.008	0.992	0.000
I67.8 Other specified cerebrovascular diseases	0.008	0.992	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.008	0.992	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.007	0.992	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.007	0.992	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.007	0.992	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.008	0.992	0.000
I27.8 Other specified pulmonary heart diseases	0.007	0.993	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.993	0.007
I27.2 Other secondary pulmonary hypertension	0.007	0.993	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.007	0.993	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.007	0.993	0.000
C45.0 Mesothelioma of pleura	0.007	0.993	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.993	0.007
I27.9 Pulmonary heart disease, unspecified	0.007	0.993	0.000
M23.3 Other meniscus derangements	0.007	0.993	0.000
I97.1 Other functional disturbances following cardiac surgery	0.006	0.993	0.000
O47.9 False labour, unspecified	0.000	0.993	0.007
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.007	0.993	0.000
I08 Multiple valve diseases	0.007	0.993	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.006	0.993	0.001
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.007	0.993	0.000
I27.0 Primary pulmonary hypertension	0.007	0.993	0.000
K35 Acute appendicitis	0.000	0.993	0.007
F20 Schizophrenia	0.006	0.994	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.994	0.006
K74.6 Other and unspecified cirrhosis of liver	0.000	0.994	0.006
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.006	0.994	0.000
C45 Mesothelioma	0.006	0.994	0.000
L03.1 Cellulitis of other parts of limb	0.006	0.994	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.006	0.994	0.000
D73.0 Hyposplenism	0.000	0.994	0.006
I98.2 Oesophageal varices in diseases classified elsewhere	0.006	0.994	0.000
K90-K93 Other diseases of the digestive system	0.000	0.994	0.006
M23.30 Other meniscus derangements (Multiple sites)	0.006	0.994	0.000
D25.1 Intramural leiomyoma of uterus	0.006	0.994	0.000
C45.9 Mesothelioma, unspecified	0.006	0.994	0.000
K70-K77 Diseases of liver	0.000	0.994	0.006
K91.3 Postoperative intestinal obstruction	0.000	0.994	0.006
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.006	0.994	0.000
K74.0 Hepatic fibrosis	0.000	0.994	0.006
C45.7 Mesothelioma of other sites	0.006	0.994	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.994	0.006
K50.1 Crohn's disease of large intestine	0.000	0.994	0.006
U81 Agent resistant to vancomycin and related antibiotics	0.000	0.994	0.005
U51 Admission status on psychiatric patients	0.000	0.994	0.006
L03.3 Cellulitis of trunk	0.006	0.994	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.005	0.994	0.000
U50 Level of care administered to neonates	0.000	0.994	0.005
U07 Emergency use of U07	0.000	0.994	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations