TreeWAS – Variant ID: rs10501858

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J84.1 Other interstitial pulmonary diseases with fibrosis	0.032	0.968	0.000
I51.7 Cardiomegaly	0.018	0.982	0.000
I51 Complications and ill-defined descriptions of heart disease	0.016	0.984	0.000
I51.8 Other ill-defined heart diseases	0.016	0.984	0.000
J84 Other interstitial pulmonary diseases	0.015	0.985	0.000
I50 Heart failure	0.014	0.986	0.000
I30-I52 Other forms of heart disease	0.014	0.986	0.000
I50.9 Heart failure, unspecified	0.014	0.986	0.000
I30 Acute pericarditis	0.013	0.987	0.000
I47 Paroxysmal tachycardia	0.013	0.987	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.013	0.987	0.000
I30.9 Acute pericarditis, unspecified	0.013	0.987	0.000
I34 Nonrheumatic mitral valve disorders	0.013	0.987	0.000
I34.0 Mitral (valve) insufficiency	0.013	0.987	0.000
I51.4 Myocarditis, unspecified	0.012	0.987	0.000
E66.9 Obesity, unspecified	0.000	0.988	0.012
I51.5 Myocardial degeneration	0.012	0.988	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.012	0.988	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.012	0.988	0.000
L57.0 Actinic keratosis	0.012	0.988	0.000
I47.1 Supraventricular tachycardia	0.011	0.989	0.000
I50.0 Congestive heart failure	0.011	0.989	0.000
I50.1 Left ventricular failure	0.011	0.989	0.000
I37 Pulmonary valve disorders	0.011	0.989	0.000
I51.6 Cardiovascular disease, unspecified	0.011	0.989	0.000
K76.8 Other specified diseases of liver	0.011	0.989	0.000
I42 Cardiomyopathy	0.011	0.989	0.000
I31 Other diseases of pericardium	0.011	0.989	0.000
J84.8 Other specified interstitial pulmonary diseases	0.011	0.989	0.000
J84.0 Alveolar and parietoalveolar conditions	0.011	0.989	0.000
I51.0 Cardiac septal defect, acquired	0.011	0.989	0.000
I47.2 Ventricular tachycardia	0.011	0.989	0.000
I33 Acute and subacute endocarditis	0.010	0.989	0.000
I38 Endocarditis, valve unspecified	0.010	0.990	0.000
I52 Other heart disorders in diseases classified elsewhere	0.010	0.990	0.000
I48 Atrial fibrillation and flutter	0.010	0.990	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.010	0.990	0.000
I41 Myocarditis in diseases classified elsewhere	0.010	0.990	0.000
I40 Acute myocarditis	0.010	0.990	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.010	0.990	0.000
I32 Pericarditis in diseases classified elsewhere	0.010	0.990	0.000
I47.0 Reentry ventricular arrhythmia	0.010	0.990	0.000
I51.9 Heart disease, unspecified	0.010	0.990	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.010	0.990	0.000
I31.3 Pericardial effusion (noninflammatory)	0.010	0.990	0.000
I30.8 Other forms of acute pericarditis	0.010	0.990	0.000
I30.1 Infective pericarditis	0.010	0.990	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.010	0.990	0.000
I36 Nonrheumatic tricuspid valve disorders	0.010	0.990	0.000
I37.1 Pulmonary valve insufficiency	0.009	0.990	0.000
E66 Obesity	0.000	0.990	0.010
I34.8 Other nonrheumatic mitral valve disorders	0.009	0.991	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.009	0.991	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.009	0.991	0.000
I42.0 Dilated cardiomyopathy	0.009	0.991	0.000
E66.8 Other obesity	0.000	0.991	0.009
C77.2 Intra-abdominal lymph nodes	0.009	0.991	0.000
I35.1 Aortic (valve) insufficiency	0.009	0.991	0.000
K76 Other diseases of liver	0.009	0.991	0.000
Z46.6 Fitting and adjustment of urinary device	0.009	0.991	0.000
I35 Nonrheumatic aortic valve disorders	0.009	0.991	0.000
I42.8 Other cardiomyopathies	0.008	0.991	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.008	0.992	0.000
I37.9 Pulmonary valve disorder, unspecified	0.008	0.992	0.000
I37.8 Other pulmonary valve disorders	0.008	0.992	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.008	0.992	0.000
I37.0 Pulmonary valve stenosis	0.008	0.992	0.000
I42.2 Other hypertrophic cardiomyopathy	0.008	0.992	0.000
K76.6 Portal hypertension	0.008	0.992	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.008	0.992	0.000
I42.6 Alcoholic cardiomyopathy	0.008	0.992	0.000
I42.5 Other restrictive cardiomyopathy	0.008	0.992	0.000
I42.4 Endocardial fibroelastosis	0.008	0.992	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.008	0.992	0.000
I31.8 Other specified diseases of pericardium	0.008	0.992	0.000
I31.2 Haemopericardium, not elsewhere classified	0.008	0.992	0.000
I31.1 Chronic constrictive pericarditis	0.008	0.992	0.000
I31.0 Chronic adhesive pericarditis	0.008	0.992	0.000
I34.1 Mitral (valve) prolapse	0.008	0.992	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.008	0.992	0.000
I33.0 Acute and subacute infective endocarditis	0.008	0.992	0.000
K76.7 Hepatorenal syndrome	0.008	0.992	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.008	0.992	0.000
I33.9 Acute endocarditis, unspecified	0.008	0.992	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.008	0.992	0.000
K29.5 Chronic gastritis, unspecified	0.000	0.992	0.008
I32.8 Pericarditis in other diseases classified elsewhere	0.007	0.992	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.007	0.992	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.007	0.992	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.007	0.992	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.007	0.992	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.007	0.992	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.007	0.992	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.007	0.992	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.007	0.992	0.000
I40.9 Acute myocarditis, unspecified	0.007	0.992	0.000
I40.8 Other acute myocarditis	0.007	0.992	0.000
I40.1 Isolated myocarditis	0.007	0.992	0.000
I40.0 Infective myocarditis	0.007	0.992	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.007	0.992	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.007	0.992	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.007	0.992	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.007	0.992	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.007	0.992	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.007	0.992	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.007	0.992	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.007	0.992	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.007	0.992	0.000
I48.4 Atypical atrial flutter	0.007	0.992	0.000
I48.3 Typical atrial flutter	0.007	0.992	0.000
I48.2 Chronic atrial fibrillation	0.007	0.992	0.000
I48.1 Persistent atrial fibrillation	0.007	0.992	0.000
I48.0 Paroxysmal atrial fibrillation	0.007	0.992	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.007	0.992	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.007	0.992	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.007	0.992	0.000
I65.2 Occlusion and stenosis of carotid artery	0.000	0.992	0.008
I46 Cardiac arrest	0.007	0.993	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.007	0.993	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.007	0.993	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.007	0.993	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.007	0.993	0.000
E66.1 Drug-induced obesity	0.000	0.993	0.007
E66.0 Obesity due to excess calories	0.000	0.993	0.007
J80 Adult respiratory distress syndrome	0.007	0.993	0.000
I31.9 Disease of pericardium, unspecified	0.007	0.993	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.007	0.993	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.993	0.007
K76.5 Hepatic veno-occlusive disease	0.007	0.993	0.000
K76.4 Peliosis hepatis	0.007	0.993	0.000
K76.3 Infarction of liver	0.007	0.993	0.000
K76.2 Central haemorrhagic necrosis of liver	0.007	0.993	0.000
K76.1 Chronic passive congestion of liver	0.007	0.993	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.006	0.993	0.000
K76.9 Liver disease, unspecified	0.006	0.993	0.000
K74.6 Other and unspecified cirrhosis of liver	0.006	0.994	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.994	0.006
I74 Arterial embolism and thrombosis	0.000	0.994	0.006
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.006	0.994	0.000
L57.5 Actinic granuloma	0.006	0.994	0.000
L57.4 Cutis laxa senilis	0.006	0.994	0.000
L57.3 Poikiloderma of Civatte	0.006	0.994	0.000
L57.2 Cutis rhomboidalis nuchae	0.006	0.994	0.000
L57.1 Actinic reticuloid	0.006	0.994	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.006	0.994	0.000
K70 Alcoholic liver disease	0.006	0.994	0.000
K70-K77 Diseases of liver	0.006	0.994	0.000
I77 Other disorders of arteries and arterioles	0.000	0.994	0.006
I35.8 Other aortic valve disorders	0.006	0.994	0.000
D69.6 Thrombocytopenia, unspecified	0.006	0.994	0.000
I42.9 Cardiomyopathy, unspecified	0.006	0.994	0.000
D69 Purpura and other haemorrhagic conditions	0.006	0.994	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.994	0.006
K90.0 Coeliac disease	0.000	0.994	0.006
D66 Hereditary factor VIII deficiency	0.006	0.994	0.000
K74 Fibrosis and cirrhosis of liver	0.005	0.994	0.000
I46.1 Sudden cardiac death, so described	0.005	0.994	0.000
K70.1 Alcoholic hepatitis	0.005	0.994	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.005	0.995	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.995	0.005
D67 Hereditary factor IX deficiency	0.005	0.995	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.995	0.005
J81 Pulmonary oedema	0.005	0.995	0.000
I46.9 Cardiac arrest, unspecified	0.005	0.995	0.000
I35.9 Aortic valve disorder, unspecified	0.005	0.995	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.995	0.005
K70.0 Alcoholic fatty liver	0.005	0.995	0.000
I44 Atrioventricular and left bundle-branch block	0.005	0.995	0.000
D68 Other coagulation defects	0.005	0.995	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.005	0.995	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.995	0.005
K70.3 Alcoholic cirrhosis of liver	0.005	0.995	0.000
I77.1 Stricture of artery	0.000	0.995	0.005
D80 Immunodeficiency with predominantly antibody defects	0.005	0.995	0.000
I73 Other peripheral vascular diseases	0.000	0.995	0.005
D76.3 Other histiocytosis syndromes	0.005	0.995	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.995	0.005
I45 Other conduction disorders	0.005	0.995	0.000
I77.6 Arteritis, unspecified	0.000	0.995	0.005
I73.0 Raynaud's syndrome	0.000	0.995	0.005
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.995	0.005
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.995	0.005
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.995	0.005
D69.4 Other primary thrombocytopenia	0.005	0.995	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.995	0.005
N84.1 Polyp of cervix uteri	0.000	0.995	0.005
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.005	0.995	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.005	0.995	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.004	0.995	0.000
D80-D89 Certain disorders involving the immune mechanism	0.005	0.995	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.004	0.995	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.005	0.995	0.000
K77 Liver disorders in diseases classified elsewhere	0.004	0.995	0.000
K71 Toxic liver disease	0.004	0.995	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.995	0.005
D75 Other diseases of blood and blood-forming organs	0.005	0.995	0.000
I44.2 Atrioventricular block, complete	0.005	0.995	0.000
I77.5 Necrosis of artery	0.000	0.995	0.004
I77.4 Coeliac artery compression syndrome	0.000	0.995	0.004
I77.3 Arterial fibromuscular dysplasia	0.000	0.995	0.004
I77.2 Rupture of artery	0.000	0.995	0.004
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.004	0.995	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.995	0.004
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.004	0.995	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.004	0.995	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.004	0.996	0.000
K70.9 Alcoholic liver disease, unspecified	0.004	0.996	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.004	0.996	0.000
K70.4 Alcoholic hepatic failure	0.004	0.996	0.000
K72 Hepatic failure, not elsewhere classified	0.004	0.996	0.000
D69.0 Allergic purpura	0.004	0.996	0.000
K74.5 Biliary cirrhosis, unspecified	0.004	0.996	0.000
D69.9 Haemorrhagic condition, unspecified	0.004	0.996	0.000
D69.8 Other specified haemorrhagic conditions	0.004	0.996	0.000
D69.2 Other nonthrombocytopenic purpura	0.004	0.996	0.000
D69.1 Qualitative platelet defects	0.004	0.996	0.000
D75.1 Secondary polycythaemia	0.004	0.996	0.000
D68.0 Von Willebrand's disease	0.004	0.996	0.000
K74.4 Secondary biliary cirrhosis	0.004	0.996	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.004	0.996	0.000
K74.1 Hepatic sclerosis	0.004	0.996	0.000
D68.2 Hereditary deficiency of other clotting factors	0.004	0.996	0.000
I71 Aortic aneurysm and dissection	0.000	0.996	0.004
D68.8 Other specified coagulation defects	0.004	0.996	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.996	0.004
I70 Atherosclerosis	0.000	0.996	0.004
D12.7 Rectosigmoid junction	0.004	0.996	0.000
R49.0 Dysphonia	0.000	0.996	0.004
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.004	0.996	0.000
I72 Other aneurysm	0.000	0.996	0.004
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.996	0.004
I44.5 Left posterior fascicular block	0.004	0.996	0.000
I44.4 Left anterior fascicular block	0.004	0.996	0.000
C67 Malignant neoplasm of bladder	0.000	0.996	0.004
K73 Chronic hepatitis, not elsewhere classified	0.004	0.996	0.000
D68.4 Acquired coagulation factor deficiency	0.004	0.996	0.000
D68.1 Hereditary factor XI deficiency	0.004	0.996	0.000
D68.6 Other Thrombophilia	0.004	0.996	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.004	0.996	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.004	0.996	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.004	0.996	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.004	0.996	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.004	0.996	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.004	0.996	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.004	0.996	0.000
D55-D59 Haemolytic anaemias	0.004	0.996	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.004	0.996	0.000
I67.8 Other specified cerebrovascular diseases	0.000	0.996	0.004
I44.6 Other and unspecified fascicular block	0.004	0.996	0.000
I45.8 Other specified conduction disorders	0.004	0.996	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.996	0.004
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.996	0.004
C67.5 Bladder neck	0.000	0.996	0.004
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.004	0.996	0.000
C79 Secondary malignant neoplasm of other sites	0.004	0.996	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.996	0.004
I44.3 Other and unspecified atrioventricular block	0.004	0.996	0.000
D69.5 Secondary thrombocytopenia	0.003	0.996	0.000
I45.4 Nonspecific intraventricular block	0.004	0.996	0.000
I45.0 Right fascicular block	0.004	0.996	0.000
I70.0 Atherosclerosis of aorta	0.000	0.996	0.004
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.004	0.996	0.000
K74.0 Hepatic fibrosis	0.003	0.996	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.996	0.004
C67.6 Ureteric orifice	0.000	0.996	0.004
D68.5 Primary Thrombophilia	0.003	0.996	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.003	0.996	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.003	0.996	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.003	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.996	0.000
D84 Other immunodeficiencies	0.003	0.996	0.000
D83 Common variable immunodeficiency	0.003	0.996	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.996	0.000
D81 Combined immunodeficiencies	0.003	0.996	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.996	0.004
K71.9 Toxic liver disease, unspecified	0.003	0.996	0.000
K71.8 Toxic liver disease with other disorders of liver	0.003	0.996	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.003	0.996	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.003	0.996	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.003	0.996	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.003	0.996	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.003	0.996	0.000
K71.2 Toxic liver disease with acute hepatitis	0.003	0.996	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.003	0.996	0.000
K71.0 Toxic liver disease with cholestasis	0.003	0.996	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.003	0.996	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.003	0.996	0.000
D74 Methaemoglobinaemia	0.003	0.996	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.003	0.996	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.003	0.996	0.000
D75.0 Familial erythrocytosis	0.003	0.996	0.000
Z45.2 Adjustment and management of vascular access device	0.004	0.996	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.003	0.997	0.000
I45.3 Trifascicular block	0.003	0.997	0.000
K72.1 Chronic hepatic failure	0.003	0.997	0.000
K72.0 Acute and subacute hepatic failure	0.003	0.997	0.000
C67.4 Posterior wall of bladder	0.000	0.997	0.003
C67.1 Dome of bladder	0.000	0.997	0.003
C79.2 Secondary malignant neoplasm of skin	0.003	0.997	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
D56 Thalassaemia	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.997	0.003
I71.0 Dissection of aorta [any part]	0.000	0.997	0.003
I45.9 Conduction disorder, unspecified	0.003	0.997	0.000
D75.2 Essential thrombocytosis	0.003	0.997	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.997	0.003
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.997	0.003
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.997	0.003
I72.3 Aneurysm of iliac artery	0.000	0.997	0.003
I72.0 Aneurysm of carotid artery	0.000	0.997	0.003
K72.9 Hepatic failure, unspecified	0.003	0.997	0.000
E65 Localised adiposity	0.000	0.997	0.003
C79.8 Secondary malignant neoplasm of other specified sites	0.003	0.997	0.000
K75 Other inflammatory liver diseases	0.003	0.997	0.000
E67 Other hyperalimentation	0.000	0.997	0.003
E68 Sequelae of hyperalimentation	0.000	0.997	0.003
I70.9 Generalised and unspecified atherosclerosis	0.000	0.997	0.003
I70.8 Atherosclerosis of other arteries	0.000	0.997	0.003
K22.7 Barrett's oesophagus	0.000	0.997	0.003
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.003	0.997	0.000
I45.1 Other and unspecified right bundle-branch block	0.003	0.997	0.000
D72 Other disorders of white blood cells	0.003	0.997	0.000
C66 Malignant neoplasm of ureter	0.000	0.997	0.003
C67.2 Lateral wall of bladder	0.000	0.997	0.003
I44.7 Left bundle-branch block, unspecified	0.003	0.997	0.000
I72.9 Aneurysm of unspecified site	0.000	0.997	0.003
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.997	0.003
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.997	0.003
I72.2 Aneurysm of renal artery	0.000	0.997	0.003
I72.1 Aneurysm of artery of upper extremity	0.000	0.997	0.003
I45.2 Bifascicular block	0.003	0.997	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.003
I79.1 Aortitis in diseases classified elsewhere	0.000	0.997	0.003
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.997	0.003
C67.8 Overlapping lesion of bladder	0.000	0.997	0.003
C67.7 Urachus	0.000	0.997	0.003
C67.3 Anterior wall of bladder	0.000	0.997	0.003
I70.1 Atherosclerosis of renal artery	0.000	0.997	0.003
I72.8 Aneurysm of other specified arteries	0.000	0.997	0.003
K73.8 Other chronic hepatitis, not elsewhere classified	0.003	0.997	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.003	0.997	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.003	0.997	0.000
I78 Diseases of capillaries	0.000	0.997	0.003
D59 Acquired haemolytic anaemia	0.003	0.997	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.003	0.997	0.000
C65 Malignant neoplasm of renal pelvis	0.000	0.997	0.003
D58 Other hereditary haemolytic anaemias	0.003	0.997	0.000
D57 Sickle-cell disorders	0.003	0.997	0.000
D55 Anaemia due to enzyme disorders	0.003	0.997	0.000
I35.0 Aortic (valve) stenosis	0.003	0.997	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.997	0.003
D73 Diseases of spleen	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
I45.6 Preexcitation syndrome	0.003	0.997	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.997	0.003
Z46 Fitting and adjustment of other devices	0.003	0.997	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.003	0.997	0.000
C77.9 Lymph node, unspecified	0.003	0.997	0.000
D56.1 Beta thalassaemia	0.003	0.997	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.003	0.997	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.003	0.997	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.003	0.997	0.000
I46.0 Cardiac arrest with successful resuscitation	0.003	0.997	0.000
D70 Agranulocytosis	0.003	0.997	0.000
D50-D53 Nutritional anaemias	0.003	0.997	0.000
C67.0 Trigone of bladder	0.000	0.997	0.003
K74.3 Primary biliary cirrhosis	0.003	0.997	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.997	0.003
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.997	0.003
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.003
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.003	0.997	0.000
L58 Radiodermatitis	0.003	0.997	0.000
L55 Sunburn	0.003	0.997	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.997	0.003
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.997	0.003
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.997	0.003
I65.1 Occlusion and stenosis of basilar artery	0.000	0.997	0.003
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.997	0.003
D81.9 Combined immunodeficiency, unspecified	0.003	0.997	0.000
D81.8 Other combined immunodeficiencies	0.003	0.997	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.997	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.997	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.997	0.000
D81.4 Nezelof's syndrome	0.003	0.997	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.997	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.997	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.997	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.997	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.997	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.997	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.997	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.997	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.997	0.000
D82.1 Di George's syndrome	0.003	0.997	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
D83.8 Other common variable immunodeficiencies	0.003	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.003	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.003	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
D74.9 Methaemoglobinaemia, unspecified	0.003	0.997	0.000
D74.8 Other methaemoglobinaemias	0.003	0.997	0.000
D74.0 Congenital methaemoglobinaemia	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
I45.5 Other specified heart block	0.003	0.997	0.000
I49 Other cardiac arrhythmias	0.003	0.997	0.000
G81.9 Hemiplegia, unspecified	0.000	0.997	0.003
K75.9 Inflammatory liver disease, unspecified	0.003	0.997	0.000
D52 Folate deficiency anaemia	0.003	0.997	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.997	0.003
I72.4 Aneurysm of artery of lower extremity	0.000	0.997	0.003
C79.7 Secondary malignant neoplasm of adrenal gland	0.003	0.997	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.003	0.997	0.000
D52.9 Folate deficiency anaemia, unspecified	0.003	0.997	0.000
D53 Other nutritional anaemias	0.003	0.997	0.000
D56.9 Thalassaemia, unspecified	0.002	0.997	0.000
D56.8 Other thalassaemias	0.002	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.997	0.000
D56.3 Thalassaemia trait	0.002	0.997	0.000
D56.2 Delta-beta thalassaemia	0.002	0.997	0.000
D56.0 Alpha thalassaemia	0.002	0.997	0.000
C79.6 Secondary malignant neoplasm of ovary	0.003	0.997	0.000
K73.9 Chronic hepatitis, unspecified	0.002	0.997	0.000
C77.8 Lymph nodes of multiple regions	0.003	0.997	0.000
J86.9 Pyothorax without fistula	0.003	0.997	0.000
E67.8 Other specified hyperalimentation	0.000	0.997	0.002
E67.3 Hypervitaminosis D	0.000	0.997	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.997	0.002
E67.1 Hypercarotenaemia	0.000	0.997	0.002
E67.0 Hypervitaminosis A	0.000	0.997	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.997	0.000
K75.2 Nonspecific reactive hepatitis	0.002	0.997	0.000
K75.1 Phlebitis of portal vein	0.002	0.997	0.000
Z48.8 Other specified surgical follow-up care	0.000	0.997	0.003
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.003	0.997	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.997	0.002
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.997	0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.997	0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.997	0.002
D60-D64 Aplastic and other anaemias	0.003	0.997	0.000
D53.9 Nutritional anaemia, unspecified	0.002	0.997	0.000
D72.9 Disorder of white blood cells, unspecified	0.002	0.997	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.997	0.000
D62 Acute posthaemorrhagic anaemia	0.003	0.997	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.997	0.002
D59.1 Other autoimmune haemolytic anaemias	0.002	0.997	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.997	0.002
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.997	0.002
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.997	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.997	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.997	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.997	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.997	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.997	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.997	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.997	0.000
Z46.8 Fitting and adjustment of other specified devices	0.002	0.997	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.998	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.998	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.998	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.998	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.998	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.998	0.000
D57.8 Other sickle-cell disorders	0.002	0.998	0.000
D57.3 Sickle-cell trait	0.002	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.002	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.002	0.998	0.000
C67.9 Bladder, unspecified	0.000	0.998	0.002
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.002	0.998	0.000
D73.4 Cyst of spleen	0.002	0.998	0.000
D73.3 Abscess of spleen	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
D73.1 Hypersplenism	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.002	0.998	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
Z46.9 Fitting and adjustment of other unspecified device	0.002	0.998	0.000
Z46.4 Fitting and adjustment of orthodontic device	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations