TreeWAS – Variant ID: rs10509586

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80 Cholelithiasis	0.000	0.075	0.925
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.081	0.919
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.084	0.916
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.129	0.871
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.209	0.791
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.239	0.761
K86 Other diseases of pancreas	0.000	0.275	0.725
K80.8 Other cholelithiasis	0.000	0.277	0.723
K85 Acute pancreatitis	0.000	0.286	0.714
K80.4 Calculus of bile duct with cholecystitis	0.000	0.303	0.697
K83 Other diseases of biliary tract	0.000	0.319	0.681
K80.3 Calculus of bile duct with cholangitis	0.000	0.337	0.663
K86.1 Other chronic pancreatitis	0.000	0.349	0.651
K85.1 Biliary acute pancreatitis	0.000	0.373	0.627
K83.8 Other specified diseases of biliary tract	0.000	0.393	0.607
K86.2 Cyst of pancreas	0.000	0.400	0.600
K85.9 Acute pancreatitis, unspecified	0.000	0.413	0.587
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.427	0.573
K86.3 Pseudocyst of pancreas	0.000	0.432	0.568
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.433	0.567
K86.8 Other specified diseases of pancreas	0.000	0.467	0.533
K83.1 Obstruction of bile duct	0.000	0.485	0.515
K85.8 Other acute pancreatitis	0.000	0.488	0.512
K85.3 Drug-induced acute pancreatitis	0.000	0.488	0.512
K85.2 Alcohol-induced acute pancreatitis	0.000	0.488	0.512
K85.0 Idiopathic acute pancreatitis	0.000	0.488	0.512
K83.9 Disease of biliary tract, unspecified	0.000	0.511	0.488
K83.5 Biliary cyst	0.000	0.511	0.488
K83.4 Spasm of sphincter of Oddi	0.000	0.511	0.488
K83.3 Fistula of bile duct	0.000	0.511	0.488
K83.2 Perforation of bile duct	0.000	0.511	0.488
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.524	0.475
K82 Other diseases of gallbladder	0.000	0.533	0.467
K83.0 Cholangitis	0.000	0.557	0.443
K81 Cholecystitis	0.000	0.582	0.418
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.593	0.407
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.593	0.407
K82.1 Hydrops of gallbladder	0.000	0.632	0.368
K82.9 Disease of gallbladder, unspecified	0.000	0.651	0.349
K82.3 Fistula of gallbladder	0.000	0.665	0.335
K82.2 Perforation of gallbladder	0.000	0.665	0.335
K82.0 Obstruction of gallbladder	0.000	0.665	0.335
K81.1 Chronic cholecystitis	0.000	0.670	0.330
K86.9 Disease of pancreas, unspecified	0.001	0.680	0.320
K81.8 Other cholecystitis	0.000	0.700	0.300
K82.4 Cholesterolosis of gallbladder	0.000	0.725	0.275
K81.0 Acute cholecystitis	0.000	0.729	0.271
K82.8 Other specified diseases of gallbladder	0.000	0.771	0.229
K81.9 Cholecystitis, unspecified	0.000	0.873	0.126
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.000	0.992	0.008
K58.9 Irritable bowel syndrome without diarrhoea	0.000	0.994	0.006
J32.9 Chronic sinusitis, unspecified	0.000	0.994	0.006
C44.1 Skin of eyelid, including canthus	0.000	0.995	0.005
N17.9 Acute renal failure, unspecified	0.005	0.995	0.000
K55.2 Angiodysplasia of colon	0.005	0.995	0.000
S22.40 Multiple fractures of ribs (closed)	0.004	0.996	0.000
R50.9 Fever, unspecified	0.000	0.996	0.004
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
N17 Acute renal failure	0.004	0.996	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
S01.4 Open wound of cheek and temporomandibular area	0.004	0.996	0.000
N17.0 Acute renal failure with tubular necrosis	0.004	0.996	0.000
S01 Open wound of head	0.004	0.996	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.996	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.996	0.000
Y45.1 Salicylates	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
Y40 Systemic antibiotics	0.003	0.997	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.997	0.003
S01.3 Open wound of ear	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
S01.5 Open wound of lip and oral cavity	0.003	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
S22.4 Multiple fractures of ribs	0.003	0.997	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
S01.2 Open wound of nose	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
N17.8 Other acute renal failure	0.003	0.997	0.000
N17.2 Acute renal failure with medullary necrosis	0.003	0.997	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.997	0.003
Y49.5 Other antipsychotics and neuroleptics	0.003	0.997	0.000
Y43 Primarily systemic agents	0.003	0.997	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.997	0.003
N18.4 Chronic kidney disease, stage 4	0.003	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
S32.40 Fracture of acetabulum (closed)	0.003	0.997	0.000
D13.1 Stomach	0.000	0.997	0.003
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45.8 Other analgesics and antipyretics	0.003	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
S01.0 Open wound of scalp	0.003	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
Y45.2 Propionic acid derivatives	0.003	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.997	0.003
S00.1 Contusion of eyelid and periocular area	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
N18.2 Chronic kidney disease, stage 2	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.003	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
S01.7 Multiple open wounds of head	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.003	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.003	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.003	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
I69.3 Sequelae of cerebral infarction	0.000	0.997	0.003
Y46.4 Iminostilbenes	0.003	0.997	0.000
Y57.7 Vitamins, not elsewhere classified	0.003	0.997	0.000
Y57.6 Other diagnostic agents	0.003	0.997	0.000
Y57.4 Pharmaceutical excipients	0.003	0.997	0.000
Y57.3 Alcohol deterrents	0.003	0.997	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Y57.1 Lipotropic drugs	0.003	0.997	0.000
Y57.0 Appetite depressants [anorectics]	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
N18 Chronic renal failure	0.003	0.997	0.000
S01.1 Open wound of eyelid and periocular area	0.003	0.997	0.000
Y40.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
Y40.6 Rifamycins	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
Y40.4 Tetracyclines	0.003	0.997	0.000
Y40.2 Chloramphenicol group	0.003	0.997	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
Y56.9 Topical agent, unspecified	0.002	0.997	0.000
Y56.8 Other topical agents	0.002	0.997	0.000
Y56.7 Dental drugs, topically applied	0.002	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.997	0.000
Y56.2 Local astringents and local detergents	0.002	0.997	0.000
Y56.1 Antipruritics	0.002	0.997	0.000
S01.9 Open wound of head, part unspecified	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
Y48.5 Therapeutic gases	0.002	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.997	0.000
Y48.3 Local anaesthetics	0.002	0.997	0.000
Y48.1 Parenteral anaesthetics	0.002	0.997	0.000
Y48.0 Inhaled anaesthetics	0.002	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
S22.41 Multiple fractures of ribs (open)	0.002	0.997	0.000
Y46.8 Antispasticity drugs	0.002	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.997	0.000
Y46.5 Valproic acid	0.002	0.997	0.000
Y46.3 Deoxybarbiturates	0.002	0.997	0.000
Y46.2 Hydantoin derivatives	0.002	0.997	0.000
Y46.1 Oxazolidinediones	0.002	0.997	0.000
Y46.0 Succinimides	0.002	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.997	0.000
Y52.7 Peripheral vasodilators	0.002	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.997	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.997	0.003
Y43.0 Antiallergic and antiemetic drugs	0.002	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.997	0.000
Y54.7 Agents affecting calcification	0.002	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.997	0.000
Y54.5 Other diuretics	0.002	0.997	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.997	0.000
Y54.0 Mineralocorticoids	0.002	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
Y41.5 Antiviral drugs	0.002	0.997	0.000
Y41.4 Anthelminthics	0.002	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.997	0.000
Y41.1 Antimycobacterial drugs	0.002	0.997	0.000
Y41.0 Sulphonamides	0.002	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.002	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.002	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.002	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.002	0.997	0.000
Y43.2 Antineoplastic natural products	0.002	0.997	0.000
N18.1 Chronic kidney disease, stage 1	0.002	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
Y53.2 Stimulant laxatives	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.998	0.000
Y55.5 Anticommon cold drugs	0.002	0.998	0.000
Y55.4 Expectorants	0.002	0.998	0.000
Y55.3 Antitussives	0.002	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.998	0.000
Y55.0 Oxytocic drugs	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
N18.8 Other chronic renal failure	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
S32.4 Fracture of acetabulum	0.002	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
K55 Vascular disorders of intestine	0.002	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
N13.8 Other obstructive and reflux uropathy	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.002	0.998	0.000
S00-S09 Injuries to the head	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
S00 Superficial injury of head	0.002	0.998	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.998	0.002
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
N18.3 Chronic kidney disease, stage 3	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
K76.8 Other specified diseases of liver	0.000	0.998	0.002
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.002	0.998	0.000
N17-N19 Renal failure	0.002	0.998	0.000
S22.3 Fracture of rib	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
H25.0 Senile incipient cataract	0.000	0.998	0.002
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.998	0.000
N18.0 End-stage renal disease	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
S01.8 Open wound of other parts of head	0.002	0.998	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
S02.6 Fracture of mandible	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
S22.9 Fracture of bony thorax, part unspecified	0.002	0.998	0.000
S22.8 Fracture of other parts of bony thorax	0.002	0.998	0.000
J32 Chronic sinusitis	0.000	0.998	0.002
S30 Superficial injury of abdomen, lower back and pelvis	0.002	0.998	0.000
K55.8 Other vascular disorders of intestine	0.002	0.998	0.000
K55.1 Chronic vascular disorders of intestine	0.002	0.998	0.000
S22.5 Flail chest	0.002	0.998	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
S02 Fracture of skull and facial bones	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
S00.9 Superficial injury of head, part unspecified	0.002	0.998	0.000
S22.1 Multiple fractures of thoracic spine	0.002	0.998	0.000
S50.8 Other superficial injuries of forearm	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
D25.9 Leiomyoma of uterus, unspecified	0.002	0.998	0.000
S00.5 Superficial injury of lip and oral cavity	0.002	0.998	0.000
S00.4 Superficial injury of ear	0.002	0.998	0.000
S22.2 Fracture of sternum	0.002	0.998	0.000
M05 Seropositive rheumatoid arthritis	0.002	0.998	0.000
S08 Traumatic amputation of part of head	0.002	0.998	0.000
S07 Crushing injury of head	0.002	0.998	0.000
S04 Injury of cranial nerves	0.002	0.998	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.002	0.998	0.000
S50 Superficial injury of forearm	0.002	0.998	0.000
D13.2 Duodenum	0.000	0.998	0.002
S00.7 Multiple superficial injuries of head	0.002	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.002	0.998	0.000
N13 Obstructive and reflux uropathy	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.002	0.998	0.000
S31.5 Open wound of other and unspecified external genital organs	0.002	0.998	0.000
S31.4 Open wound of vagina and vulva	0.002	0.998	0.000
S31.3 Open wound of scrotum and testes	0.002	0.998	0.000
S31.2 Open wound of penis	0.002	0.998	0.000
S31.0 Open wound of lower back and pelvis	0.002	0.998	0.000
Y44.2 Anticoagulants	0.002	0.998	0.000
D17 Benign lipomatous neoplasm	0.000	0.998	0.002
I67 Other cerebrovascular diseases	0.000	0.998	0.002
S22.31 Fracture of rib (open)	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
J32.4 Chronic pansinusitis	0.000	0.998	0.002
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
N13.4 Hydroureter	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S00.3 Superficial injury of nose	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.998	0.002
S06 Intracranial injury	0.002	0.998	0.000
S05 Injury of eye and orbit	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.998	0.000
I60-I69 Cerebrovascular diseases	0.000	0.998	0.002
N13.7 Vesicoureteral-reflux-associated uropathy	0.002	0.998	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.998	0.002
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.998	0.000
S30.0 Contusion of lower back and pelvis	0.002	0.998	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M20.2 Hallux rigidus	0.000	0.998	0.002
S22.0 Fracture of thoracic vertebra	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.998	0.002
S02.61 Fracture of mandible (open)	0.002	0.998	0.000
S00.0 Superficial injury of scalp	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
W94.8 Other specified place	0.002	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.002	0.998	0.000
S37 Injury of urinary and pelvic organs	0.002	0.998	0.000
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.002	0.998	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.002	0.998	0.000
M77.57 Other enthesopathy of foot-Ankle/Foot	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.000	0.998	0.002
J32.1 Chronic frontal sinusitis	0.000	0.998	0.002
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.002	0.998	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.002	0.998	0.000
S02.5 Fracture of tooth	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.002	0.998	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S30.2 Contusion of external genital organs	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
S22.51 Flail chest (open)	0.001	0.998	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.001	0.998	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.001	0.998	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.001	0.998	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.001	0.998	0.000
S92.11 Fracture of talus (open)	0.001	0.998	0.000
S92.10 Fracture of talus (closed)	0.001	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.998	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.002	0.998	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
S50-S59 Injuries to the elbow and forearm	0.002	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.998	0.001
M89.98 Disorder of bone, unspecified (Other)	0.000	0.998	0.001
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.998	0.001
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.998	0.001
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.998	0.001
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.998	0.001
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.998	0.001
S22.50 Flail chest (closed)	0.001	0.998	0.000
V09.0 Pedestrian injured in nontraffic accident involving other and unspecified motor vehicles	0.002	0.998	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.001	0.998	0.000
S22.21 Fracture of sternum (open)	0.001	0.998	0.000
S00.8 Superficial injury of other parts of head	0.002	0.998	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.001	0.998	0.000
S03.4 Sprain and strain of jaw	0.001	0.998	0.000
S03.3 Dislocation of other and unspecified parts of head	0.001	0.998	0.000
S03.2 Dislocation of tooth	0.001	0.998	0.000
S03.1 Dislocation of septal cartilage of nose	0.001	0.998	0.000
S03.0 Dislocation of jaw	0.001	0.998	0.000
S04.9 Injury of unspecified cranial nerve	0.001	0.998	0.000
S04.8 Injury of other cranial nerves	0.001	0.998	0.000
S04.7 Injury of accessory nerve	0.001	0.998	0.000
S04.6 Injury of acoustic nerve	0.001	0.998	0.000
S04.5 Injury of facial nerve	0.001	0.998	0.000
S04.4 Injury of abducent nerve	0.001	0.998	0.000
S04.3 Injury of trigeminal nerve	0.001	0.998	0.000
S04.2 Injury of trochlear nerve	0.001	0.998	0.000
S04.1 Injury of oculomotor nerve	0.001	0.998	0.000
S04.0 Injury of optic nerve and pathways	0.001	0.998	0.000
S07.9 Crushing injury of head, part unspecified	0.001	0.998	0.000
S07.8 Crushing injury of other parts of head	0.001	0.998	0.000
S07.1 Crushing injury of skull	0.001	0.998	0.000
S07.0 Crushing injury of face	0.001	0.998	0.000
S08.9 Traumatic amputation of unspecified part of head	0.001	0.998	0.000
S08.8 Traumatic amputation of other parts of head	0.001	0.998	0.000
S08.1 Traumatic amputation of ear	0.001	0.998	0.000
S08.0 Avulsion of scalp	0.001	0.998	0.000
S32.3 Fracture of ilium	0.001	0.998	0.000
S32.2 Fracture of coccyx	0.001	0.998	0.000
S32.1 Fracture of sacrum	0.001	0.998	0.000
S50.7 Multiple superficial injuries of forearm	0.001	0.998	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.001	0.998	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.998	0.002
S02.70 Multiple fractures involving skull and facial bones (closed)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations