TreeWAS – Variant ID: rs10511779

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J30.1 Allergic rhinitis due to pollen	0.000	0.982	0.018
K35 Acute appendicitis	0.000	0.985	0.015
K35.9 Acute appendicitis, unspecified	0.000	0.985	0.015
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.985	0.015
K35.8 Acute appendicitis, other and unspecified	0.000	0.985	0.015
W19.9 Unspecified place	0.000	0.986	0.014
L30.9 Dermatitis, unspecified	0.000	0.988	0.012
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.989	0.011
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.989	0.011
K35.3 Acute appendicitis with localized peritonitis	0.000	0.989	0.011
K25.7 Chronic without haemorrhage or perforation	0.010	0.990	0.000
L30 Other dermatitis	0.000	0.991	0.009
K35-K38 Diseases of appendix	0.000	0.992	0.008
K37 Unspecified appendicitis	0.000	0.992	0.008
L30.8 Other specified dermatitis	0.000	0.992	0.008
K11.2 Sialoadenitis	0.000	0.992	0.008
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.993	0.007
K11.8 Other diseases of salivary glands	0.000	0.993	0.007
L30.5 Pityriasis alba	0.000	0.993	0.006
L30.4 Erythema intertrigo	0.000	0.993	0.006
L30.3 Infective dermatitis	0.000	0.993	0.006
L30.2 Cutaneous autosensitisation	0.000	0.993	0.006
L30.1 Dyshidrosis [pompholyx]	0.000	0.993	0.006
L30.0 Nummular dermatitis	0.000	0.993	0.006
K11 Diseases of salivary glands	0.000	0.993	0.007
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.994	0.006
J30 Vasomotor and allergic rhinitis	0.000	0.994	0.006
I49.9 Cardiac arrhythmia, unspecified	0.006	0.994	0.000
D37.5 Rectum	0.000	0.994	0.006
K38 Other diseases of appendix	0.000	0.994	0.006
D37.4 Colon	0.000	0.994	0.006
K11.1 Hypertrophy of salivary gland	0.000	0.994	0.006
K11.5 Sialolithiasis	0.000	0.994	0.006
K11.6 Mucocele of salivary gland	0.000	0.994	0.006
D37.7 Other digestive organs	0.000	0.994	0.006
D37.2 Small intestine	0.000	0.995	0.005
D37.1 Stomach	0.000	0.995	0.005
D37.0 Lip, oral cavity and pharynx	0.000	0.995	0.005
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.995	0.005
K25 Gastric ulcer	0.005	0.995	0.000
K36 Other appendicitis	0.000	0.995	0.005
K11.4 Fistula of salivary gland	0.000	0.995	0.005
K11.0 Atrophy of salivary gland	0.000	0.995	0.005
L29.2 Pruritus vulvae	0.000	0.995	0.005
K38.1 Appendicular concretions	0.000	0.995	0.005
D37.9 Digestive organ, unspecified	0.000	0.995	0.005
J30.2 Other seasonal allergic rhinitis	0.000	0.995	0.005
J30.0 Vasomotor rhinitis	0.000	0.995	0.005
K38.9 Disease of appendix, unspecified	0.000	0.995	0.004
J30.3 Other allergic rhinitis	0.000	0.995	0.005
K11.7 Disturbances of salivary secretion	0.000	0.995	0.004
K38.3 Fistula of appendix	0.000	0.995	0.004
K38.2 Diverticulum of appendix	0.000	0.995	0.004
K38.0 Hyperplasia of appendix	0.000	0.995	0.004
K11.3 Abscess of salivary gland	0.000	0.995	0.004
D37.6 Liver, gallbladder and bile ducts	0.000	0.995	0.004
S83.2 Tear of meniscus, current	0.000	0.995	0.005
D37.3 Appendix	0.000	0.996	0.004
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
K25.0 Acute with haemorrhage	0.004	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
D39.1 Ovary	0.000	0.996	0.004
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.996	0.004
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.004	0.996	0.000
L29 Pruritus	0.000	0.996	0.004
K38.8 Other specified diseases of appendix	0.000	0.996	0.004
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.996	0.004
C15.5 Lower third of oesophagus	0.004	0.996	0.000
J30.4 Allergic rhinitis, unspecified	0.000	0.996	0.004
L20-L30 Dermatitis and eczema	0.000	0.996	0.004
K11.9 Disease of salivary gland, unspecified	0.000	0.996	0.004
N13.3 Other and unspecified hydronephrosis	0.004	0.996	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.004	0.996	0.000
K25.2 Acute with both haemorrhage and perforation	0.004	0.996	0.000
K25.1 Acute with perforation	0.004	0.996	0.000
K25.5 Chronic or unspecified with perforation	0.004	0.996	0.000
Y45.1 Salicylates	0.004	0.996	0.000
K25.4 Chronic or unspecified with haemorrhage	0.004	0.996	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.004	0.996	0.000
Q51.2 Other doubling of uterus	0.004	0.996	0.000
Q51.3 Bicornate uterus	0.004	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
Y45.2 Propionic acid derivatives	0.004	0.996	0.000
I49.3 Ventricular premature depolarisation	0.004	0.996	0.000
L29.0 Pruritus ani	0.000	0.996	0.004
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.996	0.003
Y45.8 Other analgesics and antipyretics	0.003	0.997	0.000
G25 Other extrapyramidal and movement disorders	0.000	0.997	0.003
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.997	0.003
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.003	0.997	0.000
G25.0 Essential tremor	0.000	0.997	0.003
K25.3 Acute without haemorrhage or perforation	0.003	0.997	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.000	0.997	0.003
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.003	0.997	0.000
I49 Other cardiac arrhythmias	0.003	0.997	0.000
L27 Dermatitis due to substances taken internally	0.001	0.997	0.002
L29.3 Anogenital pruritus, unspecified	0.000	0.997	0.003
L29.1 Pruritus scroti	0.000	0.997	0.003
L25 Unspecified contact dermatitis	0.000	0.997	0.003
L20 Atopic dermatitis	0.000	0.997	0.003
L24 Irritant contact dermatitis	0.000	0.997	0.003
L26 Exfoliative dermatitis	0.000	0.997	0.003
L22 Diaper [napkin] dermatitis	0.000	0.997	0.003
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.003	0.997	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.003	0.997	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.997	0.003
L21 Seborrhoeic dermatitis	0.000	0.997	0.003
Y45.5 4-Aminophenol derivatives	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
L23 Allergic contact dermatitis	0.000	0.997	0.003
G25.3 Myoclonus	0.000	0.997	0.003
N10-N16 Renal tubulo-interstitial diseases	0.003	0.997	0.000
N13 Obstructive and reflux uropathy	0.003	0.997	0.000
Z03.1 Observation for suspected malignant neoplasm	0.003	0.997	0.000
L29.8 Other pruritus	0.000	0.997	0.003
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.003	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.003	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.003	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.003	0.997	0.000
Q51.4 Unicornate uterus	0.003	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.003	0.997	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.003	0.997	0.000
N11 Chronic tubulo-interstitial nephritis	0.003	0.997	0.000
I49.8 Other specified cardiac arrhythmias	0.003	0.997	0.000
N13.8 Other obstructive and reflux uropathy	0.003	0.997	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.997	0.003
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.997	0.003
Q51.8 Other congenital malformations of uterus and cervix	0.003	0.997	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.997	0.003
G25.5 Other chorea	0.000	0.997	0.003
G25.4 Drug-induced chorea	0.000	0.997	0.003
G25.1 Drug-induced tremor	0.000	0.997	0.003
L28 Lichen simplex chronicus and prurigo	0.000	0.997	0.003
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.000	0.997	0.002
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.000	0.997	0.002
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.000	0.997	0.002
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.000	0.997	0.002
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.000	0.997	0.002
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.000	0.997	0.002
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.000	0.997	0.002
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.000	0.997	0.002
I49.0 Ventricular fibrillation and flutter	0.003	0.997	0.000
I49.2 Junctional premature depolarisation	0.003	0.997	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.003	0.997	0.000
D48.5 Skin	0.000	0.997	0.003
N10 Acute tubulo-interstitial nephritis	0.003	0.997	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.001	0.997	0.002
L27.8 Dermatitis due to other substances taken internally	0.001	0.997	0.002
L27.2 Dermatitis due to ingested food	0.001	0.997	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.003	0.997	0.000
I49.1 Atrial premature depolarisation	0.003	0.997	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.997	0.000
L20.9 Atopic dermatitis, unspecified	0.000	0.997	0.002
Q54 Hypospadias	0.003	0.997	0.000
L20.8 Other atopic dermatitis	0.000	0.997	0.002
L20.0 Besnier's prurigo	0.000	0.997	0.002
L25.9 Unspecified contact dermatitis, unspecified cause	0.000	0.997	0.002
L25.8 Unspecified contact dermatitis due to other agents	0.000	0.997	0.002
L25.5 Unspecified contact dermatitis due to plants, except food	0.000	0.997	0.002
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.000	0.997	0.002
L25.3 Unspecified contact dermatitis due to other chemical products	0.000	0.997	0.002
L25.2 Unspecified contact dermatitis due to dyes	0.000	0.997	0.002
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.000	0.997	0.002
L25.0 Unspecified contact dermatitis due to cosmetics	0.000	0.997	0.002
N99.5 Malfunction of external stoma of urinary tract	0.003	0.997	0.000
L24.9 Irritant contact dermatitis, unspecified cause	0.000	0.997	0.002
L24.8 Irritant contact dermatitis due to other agents	0.000	0.997	0.002
L24.7 Irritant contact dermatitis due to plants, except food	0.000	0.997	0.002
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.000	0.997	0.002
L24.5 Irritant contact dermatitis due to other chemical products	0.000	0.997	0.002
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.000	0.997	0.002
L24.3 Irritant contact dermatitis due to cosmetics	0.000	0.997	0.002
L24.2 Irritant contact dermatitis due to solvents	0.000	0.997	0.002
L24.1 Irritant contact dermatitis due to oils and greases	0.000	0.997	0.002
L24.0 Irritant contact dermatitis due to detergents	0.000	0.997	0.002
N13.6 Pyonephrosis	0.002	0.997	0.000
Q54.1 Hypospadias, penile	0.002	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
N11.1 Chronic obstructive pyelonephritis	0.002	0.997	0.000
L21.8 Other seborrhoeic dermatitis	0.000	0.997	0.002
L21.1 Seborrhoeic infantile dermatitis	0.000	0.997	0.002
L21.0 Seborrhoea capitis	0.000	0.997	0.002
L27.1 Localised skin eruption due to drugs and medicaments	0.001	0.997	0.002
L71.9 Rosacea, unspecified	0.003	0.997	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.003	0.997	0.000
N15 Other renal tubulo-interstitial diseases	0.002	0.997	0.000
R16.1 Splenomegaly, not elsewhere classified	0.002	0.997	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.000	0.998	0.002
L23.8 Allergic contact dermatitis due to other agents	0.000	0.998	0.002
L23.7 Allergic contact dermatitis due to plants, except food	0.000	0.998	0.002
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.000	0.998	0.002
L23.5 Allergic contact dermatitis due to other chemical products	0.000	0.998	0.002
L23.4 Allergic contact dermatitis due to dyes	0.000	0.998	0.002
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.000	0.998	0.002
L23.2 Allergic contact dermatitis due to cosmetics	0.000	0.998	0.002
L23.1 Allergic contact dermatitis due to adhesives	0.000	0.998	0.002
L23.0 Allergic contact dermatitis due to metals	0.000	0.998	0.002
N13.5 Kinking and stricture of ureter without hydronephrosis	0.002	0.998	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
C83.3 Large cell (diffuse)	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.000	0.998	0.002
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.998	0.002
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.002	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.002	0.998	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.002	0.998	0.000
W19 Unspecified fall	0.000	0.998	0.002
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.002	0.998	0.000
M54.22 Cervicalgia (Cervical region)	0.002	0.998	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.002	0.998	0.000
L23.9 Allergic contact dermatitis, unspecified cause	0.000	0.998	0.002
N13.7 Vesicoureteral-reflux-associated uropathy	0.002	0.998	0.000
N15.1 Renal and perinephric abscess	0.002	0.998	0.000
N99.2 Postprocedural adhesions of vagina	0.002	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.000	0.998	0.002
D39.7 Other female genital organs	0.000	0.998	0.002
D39.2 Placenta	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.002	0.998	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
L28.2 Other prurigo	0.000	0.998	0.002
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.002	0.998	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.002	0.998	0.000
N14.3 Nephropathy induced by heavy metals	0.002	0.998	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.002	0.998	0.000
N14.0 Analgesic nephropathy	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
Q54.8 Other hypospadias	0.002	0.998	0.000
Q54.4 Congenital chordee	0.002	0.998	0.000
Q54.3 Hypospadias, perineal	0.002	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Y41.5 Antiviral drugs	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.002	0.998	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.002	0.998	0.000
N15.0 Balkan nephropathy	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.998	0.000
Y41.4 Anthelminthics	0.002	0.998	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.998	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y41.0 Sulphonamides	0.002	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.998	0.002
K83.0 Cholangitis	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.000	0.998	0.002
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.002	0.998	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.002	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.002	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.002	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.002	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.002	0.998	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
W19.8 Other specified place	0.000	0.998	0.002
W19.5 Trade and service area	0.000	0.998	0.002
W19.0 Home	0.000	0.998	0.002
W19.7 Farm	0.000	0.998	0.002
W19.6 Industrial and construction area	0.000	0.998	0.002
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
M75.0 Adhesive capsulitis of shoulder	0.000	0.998	0.002
N99.0 Postprocedural renal failure	0.002	0.998	0.000
D39.0 Uterus	0.000	0.998	0.002
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
I49.4 Other and unspecified premature depolarisation	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.998	0.002
M86.98 Osteomyelitis, unspecified (Other)	0.002	0.998	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
L28.1 Prurigo nodularis	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.998	0.000
W19.3 Sports and athletics area	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Q53 Undescended testicle	0.002	0.998	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.998	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.002	0.998	0.000
R52.1 Chronic intractable pain	0.000	0.998	0.002
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.002	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.002	0.998	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
B37.9 Candidiasis, unspecified	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.002	0.998	0.000
Q50.2 Congenital torsion of ovary	0.002	0.998	0.000
Q50.1 Developmental ovarian cyst	0.002	0.998	0.000
Q50.0 Congenital absence of ovary	0.002	0.998	0.000
W19.2 School, other institution and public administrative area	0.000	0.998	0.002
Y54.5 Other diuretics	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.1 Doubling of vagina	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.002	0.998	0.000
I49.5 Sick sinus syndrome	0.002	0.998	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.000	0.998	0.002
Y59.3 Immunoglobulin	0.002	0.998	0.000
D10 Benign neoplasm of mouth and pharynx	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
W19.09 Unspecified fall; Home; During unspecified activity	0.000	0.998	0.001
W19.08 Unspecified fall; Home; While engaged in other specified activities	0.000	0.998	0.001
W19.59 Unspecified fall; Trade and service area; During unspecified activity	0.000	0.998	0.001
W19.81 Unspecified fall; Other specified places; While engaged in leisure activity	0.000	0.998	0.001
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
W19.1 Residential institution	0.000	0.998	0.001
Y47.1 Benzodiazepines	0.002	0.998	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
E14.9 Without complications	0.002	0.998	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
N99.1 Postprocedural urethral stricture	0.001	0.998	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.998	0.000
Y47.4 Bromine compounds	0.001	0.998	0.000
Y47.3 Paraldehyde	0.001	0.998	0.000
Y47.2 Chloral derivatives	0.001	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.998	0.000
Y59.9 Vaccine or biological substance, unspecified	0.001	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.998	0.000
Y59.2 Protozoal vaccines	0.001	0.998	0.000
Y59.1 Rickettsial vaccines	0.001	0.998	0.000
Y59.0 Viral vaccines	0.001	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.998	0.002
D10.1 Tongue	0.002	0.998	0.000
D10.0 Lip	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y49.9 Psychotropic drug, unspecified	0.001	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.001	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.001	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.001	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.998	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.998	0.000
M89 Other disorders of bone	0.002	0.998	0.000
Q53.9 Undescended testicle, unspecified	0.001	0.998	0.000
Q53.2 Undescended testicle, bilateral	0.001	0.998	0.000
Q53.0 Ectopic testis	0.001	0.998	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.002	0.998	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.002	0.998	0.000
N28.1 Cyst of kidney, acquired	0.000	0.998	0.002
S83.7 Injury to multiple structures of knee	0.000	0.998	0.001
S83.3 Tear of articular cartilage of knee, current	0.000	0.998	0.001
S83.1 Dislocation of knee	0.000	0.998	0.001
S83.0 Dislocation of patella	0.000	0.998	0.001
Y49.5 Other antipsychotics and neuroleptics	0.001	0.998	0.000
Y50.9 Central nervous system stimulant, unspecified	0.001	0.998	0.000
Y50.8 Other central nervous system stimulants	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y50.1 Opioid receptor antagonists	0.001	0.998	0.000
Y50.0 Analeptics	0.001	0.998	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
Y55.5 Anticommon cold drugs	0.001	0.998	0.000
Y55.4 Expectorants	0.001	0.998	0.000
Y55.3 Antitussives	0.001	0.998	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
Y55.0 Oxytocic drugs	0.001	0.998	0.000
Y56.9 Topical agent, unspecified	0.001	0.998	0.000
Y56.8 Other topical agents	0.001	0.998	0.000
Y56.7 Dental drugs, topically applied	0.001	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.001	0.998	0.000
Y56.2 Local astringents and local detergents	0.001	0.998	0.000
Y56.1 Antipruritics	0.001	0.998	0.000
M89.98 Disorder of bone, unspecified (Other)	0.001	0.998	0.000
C71.1 Frontal lobe	0.000	0.998	0.002
D10.5 Other parts of oropharynx	0.002	0.998	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.998	0.002
C15 Malignant neoplasm of oesophagus	0.002	0.998	0.000
Y48 Anaesthetics and therapeutic gases	0.001	0.998	0.000
A04.7 Enterocolitis due to Clostridium difficile	0.002	0.998	0.000
D48.7 Other specified sites	0.000	0.998	0.001
D48.4 Peritoneum	0.000	0.998	0.001
D48.3 Retroperitoneum	0.000	0.998	0.001
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.998	0.001
G00.2 Streptococcal meningitis	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
Y53.7 Emetics	0.001	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.001	0.998	0.000
Y53.5 Digestants	0.001	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.001	0.998	0.000
Y53.2 Stimulant laxatives	0.001	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.001	0.998	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.002	0.998	0.000
D10.9 Pharynx, unspecified	0.002	0.998	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.000	0.998	0.002
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.998	0.002
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
Y54.3 Benzothiadiazine derivatives	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations