TreeWAS – Variant ID: rs10515148

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.308	0.692	0.000
I49 Other cardiac arrhythmias	0.159	0.841	0.000
I49.5 Sick sinus syndrome	0.156	0.844	0.000
I49.8 Other specified cardiac arrhythmias	0.155	0.845	0.000
I49.9 Cardiac arrhythmia, unspecified	0.151	0.849	0.000
I49.1 Atrial premature depolarisation	0.144	0.856	0.000
I49.4 Other and unspecified premature depolarisation	0.135	0.865	0.000
I49.3 Ventricular premature depolarisation	0.120	0.880	0.000
C77.1 Intrathoracic lymph nodes	0.115	0.885	0.000
E03 Other hypothyroidism	0.114	0.886	0.000
I49.2 Junctional premature depolarisation	0.114	0.886	0.000
E03.5 Myxoedema coma	0.082	0.918	0.000
E03.4 Atrophy of thyroid (acquired)	0.082	0.918	0.000
E03.3 Postinfectious hypothyroidism	0.082	0.918	0.000
E03.1 Congenital hypothyroidism without goitre	0.082	0.918	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.082	0.918	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.079	0.921	0.000
E03.8 Other specified hypothyroidism	0.064	0.935	0.000
I49.0 Ventricular fibrillation and flutter	0.055	0.944	0.000
G62 Other polyneuropathies	0.046	0.954	0.000
G62.9 Polyneuropathy, unspecified	0.045	0.955	0.000
G61.0 Guillain-Barre syndrome	0.045	0.955	0.000
G61 Inflammatory polyneuropathy	0.043	0.957	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.042	0.958	0.000
G62.0 Drug-induced polyneuropathy	0.041	0.959	0.000
G62.1 Alcoholic polyneuropathy	0.038	0.962	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.038	0.962	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.035	0.965	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.035	0.965	0.000
C77.2 Intra-abdominal lymph nodes	0.035	0.965	0.000
G62.2 Polyneuropathy due to other toxic agents	0.033	0.967	0.000
E10 Insulin-dependent diabetes mellitus	0.033	0.967	0.000
G62.8 Other specified polyneuropathies	0.032	0.968	0.000
G61.1 Serum neuropathy	0.031	0.969	0.000
E00-E07 Disorders of thyroid gland	0.031	0.969	0.000
E10.0 With coma	0.031	0.969	0.000
G64 Other disorders of peripheral nervous system	0.030	0.970	0.000
G63.2 Diabetic polyneuropathy	0.030	0.970	0.000
E10.2 With renal complications	0.030	0.970	0.000
C77.9 Lymph node, unspecified	0.030	0.970	0.000
E10.9 Without complications	0.028	0.972	0.000
E10.5 With peripheral circulatory complications	0.028	0.972	0.000
C77.5 Intrapelvic lymph nodes	0.027	0.973	0.000
E10.3 With ophthalmic complications	0.027	0.973	0.000
E10.7 With multiple complications	0.026	0.974	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.025	0.975	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.025	0.975	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.025	0.975	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.025	0.975	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.025	0.975	0.000
G63.1 Polyneuropathy in neoplastic disease	0.025	0.975	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.025	0.975	0.000
E10.1 With ketoacidosis	0.025	0.975	0.000
G60 Hereditary and idiopathic neuropathy	0.025	0.975	0.000
E10-E14 Diabetes mellitus	0.024	0.976	0.000
E07 Other disorders of thyroid	0.024	0.976	0.000
E10.6 With other specified complications	0.023	0.977	0.000
E10.8 With unspecified complications	0.022	0.977	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.022	0.977	0.000
E00 Congenital iodine-deficiency syndrome	0.022	0.977	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.022	0.977	0.000
G61.8 Other inflammatory polyneuropathies	0.022	0.977	0.000
E11 Non-insulin-dependent diabetes mellitus	0.021	0.979	0.000
E10.4 With neurological complications	0.020	0.980	0.000
E11.3 With ophthalmic complications	0.020	0.980	0.000
E06 Thyroiditis	0.019	0.980	0.000
C77.8 Lymph nodes of multiple regions	0.019	0.981	0.000
E11.1 With ketoacidosis	0.019	0.981	0.000
E07.8 Other specified disorders of thyroid	0.018	0.982	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.018	0.982	0.000
G60.3 Idiopathic progressive neuropathy	0.018	0.982	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.018	0.982	0.000
G60.1 Refsum's disease	0.018	0.982	0.000
E12 Malnutrition-related diabetes mellitus	0.018	0.982	0.000
C77.0 Lymph nodes of head, face and neck	0.018	0.982	0.000
E13 Other specified diabetes mellitus	0.018	0.982	0.000
E11.4 With neurological complications	0.017	0.983	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.017	0.983	0.000
E07.1 Dyshormogenetic goitre	0.017	0.983	0.000
E07.0 Hypersecretion of calcitonin	0.017	0.983	0.000
E11.2 With renal complications	0.017	0.983	0.000
E07.9 Disorder of thyroid, unspecified	0.017	0.983	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.016	0.984	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.016	0.984	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.016	0.984	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.016	0.984	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.016	0.984	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.016	0.984	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.016	0.984	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.016	0.984	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.016	0.984	0.000
E11.6 With other specified complications	0.016	0.984	0.000
E11.8 With unspecified complications	0.016	0.984	0.000
E06.9 Thyroiditis, unspecified	0.016	0.984	0.000
E11.7 With multiple complications	0.015	0.984	0.000
G60.0 Hereditary motor and sensory neuropathy	0.015	0.985	0.000
E04 Other non-toxic goitre	0.015	0.985	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.014	0.986	0.000
E06.5 Other chronic thyroiditis	0.014	0.986	0.000
E06.4 Drug-induced thyroiditis	0.014	0.986	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.014	0.986	0.000
E06.1 Subacute thyroiditis	0.014	0.986	0.000
E06.0 Acute thyroiditis	0.014	0.986	0.000
E50-E64 Other nutritional deficiencies	0.014	0.986	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.014	0.986	0.000
N00-N08 Glomerular diseases	0.014	0.986	0.000
E11.5 With peripheral circulatory complications	0.013	0.987	0.000
N05 Unspecified nephritic syndrome	0.013	0.987	0.000
E04.9 Non-toxic goitre, unspecified	0.013	0.987	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.013	0.987	0.000
E12.9 Without complications	0.013	0.987	0.000
E12.8 With unspecified complications	0.013	0.987	0.000
E12.7 With multiple complications	0.013	0.987	0.000
E12.6 With other specified complications	0.013	0.987	0.000
E12.5 With peripheral circulatory complications	0.013	0.987	0.000
E12.4 With neurological complications	0.013	0.987	0.000
E12.3 With ophthalmic complications	0.013	0.987	0.000
E12.2 With renal complications	0.013	0.987	0.000
E12.1 With ketoacidosis	0.013	0.987	0.000
E12.0 With coma	0.013	0.987	0.000
E13.8 With unspecified complications	0.013	0.987	0.000
E13.7 With multiple complications	0.013	0.987	0.000
E13.6 With other specified complications	0.013	0.987	0.000
E13.5 With peripheral circulatory complications	0.013	0.987	0.000
E13.4 With neurological complications	0.013	0.987	0.000
E13.3 With ophthalmic complications	0.013	0.987	0.000
E13.2 With renal complications	0.013	0.987	0.000
E13.1 With ketoacidosis	0.013	0.987	0.000
E13.0 With coma	0.013	0.987	0.000
E13.9 Without complications	0.013	0.987	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.013	0.987	0.000
N03 Chronic nephritic syndrome	0.013	0.987	0.000
E14 Unspecified diabetes mellitus	0.012	0.987	0.000
N05.9 Unspecified	0.012	0.988	0.000
E11.0 With coma	0.012	0.988	0.000
N02 Recurrent and persistent haematuria	0.012	0.988	0.000
E65-E68 Obesity and other hyperalimentation	0.012	0.988	0.000
E56 Other vitamin deficiencies	0.012	0.988	0.000
E58 Dietary calcium deficiency	0.012	0.988	0.000
E51 Thiamine deficiency	0.011	0.989	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.011	0.989	0.000
N03.9 Unspecified	0.011	0.989	0.000
E04.8 Other specified non-toxic goitre	0.011	0.989	0.000
E65 Localised adiposity	0.011	0.989	0.000
C77.4 Inguinal and lower limb lymph nodes	0.010	0.989	0.000
N04 Nephrotic syndrome	0.011	0.989	0.000
N05.1 Focal and segmental glomerular lesions	0.011	0.989	0.000
E61 Deficiency of other nutrient elements	0.011	0.989	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.010	0.989	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.010	0.989	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.010	0.989	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.010	0.989	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.010	0.989	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.010	0.989	0.000
E04.1 Non-toxic single thyroid nodule	0.010	0.990	0.000
E14.4 With neurological complications	0.010	0.990	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.010	0.990	0.000
E63 Other nutritional deficiencies	0.010	0.990	0.000
E50 Vitamin A deficiency	0.010	0.990	0.000
E60 Dietary zinc deficiency	0.010	0.990	0.000
E59 Dietary selenium deficiency	0.010	0.990	0.000
E54 Ascorbic acid deficiency	0.010	0.990	0.000
E52 Niacin deficiency [pellagra]	0.010	0.990	0.000
N03.1 Focal and segmental glomerular lesions	0.010	0.990	0.000
E56.1 Deficiency of vitamin K	0.010	0.990	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.010	0.990	0.000
N06 Isolated proteinuria with specified morphological lesion	0.010	0.990	0.000
N01 Rapidly progressive nephritic syndrome	0.010	0.990	0.000
N00 Acute nephritic syndrome	0.010	0.990	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.010	0.990	0.000
N02.9 Unspecified	0.010	0.990	0.000
E40-E46 Malnutrition	0.010	0.990	0.000
E14.6 With other specified complications	0.010	0.990	0.000
N02.8 Other	0.010	0.990	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.010	0.990	0.000
C71.2 Temporal lobe	0.010	0.990	0.000
E14.8 With unspecified complications	0.010	0.990	0.000
E14.2 Withrenal complications	0.010	0.990	0.000
N05.6 Dense deposit disease	0.010	0.990	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.010	0.990	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.010	0.990	0.000
N05.0 Minor glomerular abnormality	0.010	0.990	0.000
C71 Malignant neoplasm of brain	0.010	0.990	0.000
E05.8 Other thyrotoxicosis	0.010	0.990	0.000
E05.5 Thyroid crisis or storm	0.010	0.990	0.000
E05.4 Thyrotoxicosis factitia	0.010	0.990	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.010	0.990	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.010	0.990	0.000
E55 Vitamin D deficiency	0.010	0.990	0.000
N03.8 Other	0.009	0.991	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.009	0.991	0.000
N03.6 Dense deposit disease	0.009	0.991	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.009	0.991	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.009	0.991	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.009	0.991	0.000
N03.2 Diffuse membranous glomerulonephritis	0.009	0.991	0.000
N03.0 Minor glomerular abnormality	0.009	0.991	0.000
E14.7 With multiple complications	0.009	0.991	0.000
E14.5 With peripheral circulatory complications	0.009	0.991	0.000
E14.1 With ketoacidosis	0.009	0.991	0.000
E14.0 With coma	0.009	0.991	0.000
E04.0 Non-toxic diffuse goitre	0.009	0.991	0.000
E51.2 Wernicke's encephalopathy	0.009	0.991	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.009	0.991	0.000
N02.6 Dense deposit disease	0.009	0.991	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.009	0.991	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.009	0.991	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.009	0.991	0.000
N02.2 Diffuse membranous glomerulonephritis	0.009	0.991	0.000
N02.1 Focal and segmental glomerular lesions	0.009	0.991	0.000
N02.0 Minor glomerular abnormality	0.009	0.991	0.000
C71.9 Brain, unspecified	0.009	0.991	0.000
E61.2 Magnesium deficiency	0.009	0.991	0.000
N05.8 Other	0.009	0.991	0.000
E67 Other hyperalimentation	0.009	0.991	0.000
E68 Sequelae of hyperalimentation	0.009	0.991	0.000
E56.9 Vitamin deficiency, unspecified	0.009	0.991	0.000
E56.8 Deficiency of other vitamins	0.009	0.991	0.000
E56.0 Deficiency of vitamin E	0.009	0.991	0.000
N05.2 Diffuse membranous glomerulonephritis	0.009	0.991	0.000
N04.1 Focal and segmental glomerular lesions	0.009	0.991	0.000
E51.9 Thiamine deficiency, unspecified	0.008	0.992	0.000
E51.8 Other manifestations of thiamine deficiency	0.008	0.992	0.000
E51.1 Beriberi	0.008	0.992	0.000
Y84.2 Radiological procedure and radiotherapy	0.008	0.992	0.000
N04.8 Other	0.008	0.992	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.008	0.992	0.000
N04.6 Dense deposit disease	0.008	0.992	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.008	0.992	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.008	0.992	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.008	0.992	0.000
N04.2 Diffuse membranous glomerulonephritis	0.008	0.992	0.000
N04.0 Minor glomerular abnormality	0.008	0.992	0.000
E06.3 Autoimmune thyroiditis	0.008	0.992	0.000
E61.9 Deficiency of nutrient element, unspecified	0.008	0.992	0.000
E61.8 Deficiency of other specified nutrient elements	0.008	0.992	0.000
E61.7 Deficiency of multiple nutrient elements	0.008	0.992	0.000
E61.6 Vanadium deficiency	0.008	0.992	0.000
E61.5 Molybdenum deficiency	0.008	0.992	0.000
E61.4 Chromium deficiency	0.008	0.992	0.000
E61.3 Manganese deficiency	0.008	0.992	0.000
E61.0 Copper deficiency	0.008	0.992	0.000
N04.9 Unspecified	0.008	0.992	0.000
C71.1 Frontal lobe	0.008	0.992	0.000
E53 Deficiency of other B group vitamins	0.007	0.992	0.001
C71.0 Cerebrum, except lobes and ventricles	0.008	0.992	0.000
E50.9 Vitamin A deficiency, unspecified	0.007	0.992	0.000
E50.8 Other manifestations of vitamin A deficiency	0.007	0.992	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.007	0.992	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.007	0.992	0.000
E50.5 Vitamin A deficiency with night blindness	0.007	0.992	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.007	0.992	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.007	0.992	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.007	0.992	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.007	0.992	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.007	0.992	0.000
E63.9 Nutritional deficiency, unspecified	0.007	0.992	0.000
E63.8 Other specified nutritional deficiencies	0.007	0.992	0.000
E63.1 Imbalance of constituents of food intake	0.007	0.992	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.007	0.992	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.007	0.992	0.000
E64.8 Sequelae of other nutritional deficiencies	0.007	0.992	0.000
E64.3 Sequelae of rickets	0.007	0.992	0.000
E64.2 Sequelae of vitamin C deficiency	0.007	0.992	0.000
E64.1 Sequelae of vitamin A deficiency	0.007	0.992	0.000
E64.0 Sequelae of protein-energy malnutrition	0.007	0.992	0.000
N00.9 Unspecified	0.007	0.992	0.000
N00.8 Other	0.007	0.992	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.007	0.992	0.000
N00.6 Dense deposit disease	0.007	0.992	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.007	0.992	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.007	0.992	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.007	0.992	0.000
N00.2 Diffuse membranous glomerulonephritis	0.007	0.992	0.000
N00.1 Focal and segmental glomerular lesions	0.007	0.992	0.000
N00.0 Minor glomerular abnormality	0.007	0.992	0.000
N01.9 Unspecified	0.007	0.992	0.000
N01.8 Other	0.007	0.992	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.007	0.992	0.000
N01.6 Dense deposit disease	0.007	0.992	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.007	0.992	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.007	0.992	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.007	0.992	0.000
N01.2 Diffuse membranous glomerulonephritis	0.007	0.992	0.000
N01.1 Focal and segmental glomerular lesions	0.007	0.992	0.000
N01.0 Minor glomerular abnormality	0.007	0.992	0.000
N06.9 Unspecified	0.007	0.992	0.000
N06.8 Other	0.007	0.992	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.007	0.992	0.000
N06.6 Dense deposit disease	0.007	0.992	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.007	0.992	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.007	0.992	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.007	0.992	0.000
N06.2 Diffuse membranous glomerulonephritis	0.007	0.992	0.000
N06.1 Focal and segmental glomerular lesions	0.007	0.992	0.000
N06.0 Minor glomerular abnormality	0.007	0.992	0.000
N07.9 Unspecified	0.007	0.992	0.000
N07.8 Other	0.007	0.992	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.007	0.992	0.000
N07.6 Dense deposit disease	0.007	0.992	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.007	0.992	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.007	0.992	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.007	0.992	0.000
N07.2 Diffuse membranous glomerulonephritis	0.007	0.992	0.000
N07.1 Focal and segmental glomerular lesions	0.007	0.992	0.000
N07.0 Minor glomerular abnormality	0.007	0.992	0.000
E15 Nondiabetic hypoglycaemic coma	0.007	0.992	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.007	0.992	0.000
E45 Retarded development following protein-energy malnutrition	0.007	0.992	0.000
E43 Unspecified severe protein-energy malnutrition	0.007	0.992	0.000
E42 Marasmic kwashiorkor	0.007	0.992	0.000
E41 Nutritional marasmus	0.007	0.992	0.000
E40 Kwashiorkor	0.007	0.992	0.000
C71.3 Parietal lobe	0.007	0.992	0.000
C71.8 Overlapping lesion of brain	0.007	0.992	0.000
C71.7 Brain stem	0.007	0.993	0.000
C71.6 Cerebellum	0.007	0.993	0.000
C71.5 Cerebral ventricle	0.007	0.993	0.000
C71.4 Occipital lobe	0.007	0.993	0.000
G51.0 Bell's palsy	0.000	0.993	0.007
E55.0 Rickets, active	0.007	0.993	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.993	0.007
Y84.9 Medical procedure, unspecified	0.007	0.993	0.000
E61.1 Iron deficiency	0.007	0.993	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.007	0.993	0.000
N75.0 Cyst of Bartholin's gland	0.000	0.993	0.007
K52.8 Other specified non-infective gastro-enteritis and colitis	0.007	0.993	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.007	0.993	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.007	0.993	0.000
Y84.8 Other medical procedures	0.007	0.993	0.000
C69 Malignant neoplasm of eye and adnexa	0.007	0.993	0.000
E67.8 Other specified hyperalimentation	0.006	0.993	0.000
E67.3 Hypervitaminosis D	0.006	0.993	0.000
E67.2 Megavitamin-B6 syndrome	0.006	0.993	0.000
E67.1 Hypercarotenaemia	0.006	0.993	0.000
E67.0 Hypervitaminosis A	0.006	0.993	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.007	0.993	0.000
E53.9 Vitamin B deficiency, unspecified	0.006	0.994	0.000
E55.9 Vitamin D deficiency, unspecified	0.006	0.994	0.000
C69.3 Choroid	0.006	0.994	0.000
J92.0 Pleural plaque with presence of asbestos	0.006	0.994	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.006	0.994	0.000
E53.1 Pyridoxine deficiency	0.005	0.994	0.001
E53.0 Riboflavin deficiency	0.005	0.994	0.001
C69.9 Eye, unspecified	0.006	0.994	0.000
E44.1 Mild protein-energy malnutrition	0.005	0.994	0.000
E44.0 Moderate protein-energy malnutrition	0.005	0.994	0.000
O42.9 Premature rupture of membranes, unspecified	0.006	0.994	0.000
C69.6 Orbit	0.006	0.994	0.000
I50.0 Congestive heart failure	0.005	0.995	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.005	0.995	0.000
Y84.7 Blood-sampling	0.005	0.995	0.000
Y84.5 Insertion of gastric or duodenal sound	0.005	0.995	0.000
Y84.3 Shock therapy	0.005	0.995	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.005	0.995	0.000
C70 Malignant neoplasm of meninges	0.005	0.995	0.000
C69.8 Overlapping lesion of eye and adnexa	0.005	0.995	0.000
C69.5 Lachrymal gland and duct	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
C69.2 Retina	0.005	0.995	0.000
C69.1 Cornea	0.005	0.995	0.000
C69.0 Conjunctiva	0.005	0.995	0.000
Y84.1 Kidney dialysis	0.005	0.995	0.000
E16 Other disorders of pancreatic internal secretion	0.005	0.995	0.000
E46 Unspecified protein-energy malnutrition	0.005	0.995	0.000
Y84.4 Aspiration of fluid	0.005	0.995	0.000
T31.0 Burns involving less than 10% of body surface	0.000	0.995	0.005
E14.3 With ophthalmic complications	0.005	0.995	0.000
Y84.0 Cardiac catheterisation	0.005	0.995	0.000
Y84.6 Urinary catheterisation	0.005	0.995	0.000
I44.2 Atrioventricular block, complete	0.004	0.996	0.000
E05.9 Thyrotoxicosis, unspecified	0.004	0.996	0.000
F32.9 Depressive episode, unspecified	0.000	0.996	0.004
Z95.0 Presence of cardiac pacemaker	0.004	0.996	0.000
C70.9 Meninges, unspecified	0.004	0.996	0.000
C70.1 Spinal meninges	0.004	0.996	0.000
C70.0 Cerebral meninges	0.004	0.996	0.000
C72.9 Central nervous system, unspecified	0.004	0.996	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.996	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.996	0.000
C72.4 Acoustic nerve	0.004	0.996	0.000
C72.3 Optic nerve	0.004	0.996	0.000
C72.2 Olfactory nerve	0.004	0.996	0.000
C72.1 Cauda equina	0.004	0.996	0.000
C72.0 Spinal cord	0.004	0.996	0.000
K04.5 Chronic apical periodontitis	0.000	0.996	0.004
E16.9 Disorder of pancreatic internal secretion, unspecified	0.004	0.996	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.004	0.996	0.000
E16.4 Abnormal secretion of gastrin	0.004	0.996	0.000
E16.3 Increased secretion of glucagon	0.004	0.996	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.004	0.996	0.000
B34.9 Viral infection, unspecified	0.000	0.996	0.004
C25.9 Pancreas, unspecified	0.000	0.996	0.004
E16.1 Other hypoglycaemia	0.003	0.996	0.000
G51 Facial nerve disorders	0.000	0.996	0.004
F32.1 Moderate depressive episode	0.000	0.996	0.003
B02.9 Zoster without complication	0.000	0.997	0.003
S81.9 Open wound of lower leg, part unspecified	0.000	0.997	0.003
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
F32 Depressive episode	0.000	0.997	0.003
L81.8 Other specified disorders of pigmentation	0.003	0.997	0.000
M47.9 Spondylosis, unspecified	0.003	0.997	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.997	0.003
G51.9 Disorder of facial nerve, unspecified	0.000	0.997	0.003
S52.00 Fracture of upper end of ulna (closed)	0.000	0.997	0.003
G51.8 Other disorders of facial nerve	0.000	0.997	0.003
I35.2 Aortic (valve) stenosis with insufficiency	0.003	0.997	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
S51.8 Open wound of other parts of forearm	0.000	0.997	0.003
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.997	0.003
O42 Premature rupture of membranes	0.003	0.997	0.000
T31 Burns classified according to extent of body surface involved	0.000	0.997	0.003
G51.4 Facial myokymia	0.000	0.997	0.003
G51.2 Melkersson's syndrome	0.000	0.997	0.003
G51.1 Geniculate ganglionitis	0.000	0.997	0.003
N21.0 Calculus in bladder	0.000	0.997	0.003
M47.94 Spondylosis, unspecified (Thoracic region)	0.003	0.997	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.997	0.000
F32.8 Other depressive episodes	0.000	0.997	0.002
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.002	0.997	0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.002	0.997	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.002	0.997	0.000
C77.3 Axillary and upper limb lymph nodes	0.002	0.997	0.000
G51.3 Clonic hemifacial spasm	0.000	0.998	0.002
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.998	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.002	0.998	0.000
L81.9 Disorder of pigmentation, unspecified	0.002	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.998	0.002
S81 Open wound of lower leg	0.000	0.998	0.002
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.998	0.000
T31.9 Burns involving 90% or more of body surface	0.000	0.998	0.002
T31.8 Burns involving 80-89% of body surface	0.000	0.998	0.002
T31.7 Burns involving 70-79% of body surface	0.000	0.998	0.002
T31.6 Burns involving 60-69% of body surface	0.000	0.998	0.002
T31.5 Burns involving 50-59% of body surface	0.000	0.998	0.002
T31.4 Burns involving 40-49% of body surface	0.000	0.998	0.002
T31.3 Burns involving 30-39% of body surface	0.000	0.998	0.002
T31.2 Burns involving 20-29% of body surface	0.000	0.998	0.002
T31.1 Burns involving 10-19% of body surface	0.000	0.998	0.002
E04.2 Non-toxic multinodular goitre	0.002	0.998	0.000
N75 Diseases of Bartholin's gland	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
J92 Pleural plaque	0.002	0.998	0.000
M47.82 Other spondylosis (Cervical region)	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.001	0.998	0.002
R41.0 Disorientation, unspecified	0.000	0.998	0.002
I50 Heart failure	0.002	0.998	0.000
H35.0 Background retinopathy and retinal vascular changes	0.002	0.998	0.000
E66 Obesity	0.002	0.998	0.000
M47.96 Spondylosis, unspecified (Lumbar region)	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.001
K35.0 Acute appendicitis with generalised peritonitis	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.002	0.998	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
F32.0 Mild depressive episode	0.000	0.998	0.002
S51 Open wound of forearm	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
N75.9 Disease of Bartholin's gland, unspecified	0.000	0.998	0.002
N75.8 Other diseases of Bartholin's gland	0.000	0.998	0.002
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.998	0.002
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.000	0.998	0.002
G71.1 Myotonic disorders	0.002	0.998	0.000
M47.8 Other spondylosis	0.002	0.998	0.000
E29 Testicular dysfunction	0.001	0.998	0.001
L81 Other disorders of pigmentation	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
M35.3 Polymyalgia rheumatica	0.002	0.998	0.000
B02 Zoster [herpes zoster]	0.000	0.998	0.002
E66.1 Drug-induced obesity	0.002	0.998	0.000
E24 Cushing's syndrome	0.001	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
B02.3 Zoster ocular disease	0.000	0.998	0.002
S51.7 Multiple open wounds of forearm	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.001	0.998	0.001
E32 Diseases of thymus	0.001	0.998	0.001
E31 Polyglandular dysfunction	0.001	0.998	0.001
E30 Disorders of puberty, not elsewhere classified	0.001	0.998	0.001
E25 Adrenogenital disorders	0.001	0.998	0.001
I30-I52 Other forms of heart disease	0.002	0.998	0.000
B34 Viral infection of unspecified site	0.000	0.998	0.002
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.998	0.002
I40.0 Infective myocarditis	0.002	0.998	0.000
E34 Other endocrine disorders	0.001	0.998	0.001
I40 Acute myocarditis	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.002	0.998	0.000
E26 Hyperaldosteronism	0.001	0.998	0.001
E20 Hypoparathyroidism	0.001	0.998	0.001
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
D12.0 Caecum	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations