TreeWAS – Variant ID: rs1052248

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40.0 Psoriasis vulgaris	0.973	0.027	0.000
L40.8 Other psoriasis	0.869	0.131	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.776	0.224	0.000
Chapter V Mental and behavioural disorders	0.774	0.226	0.000
F41 Other anxiety disorders	0.759	0.241	0.000
F30-F39 Mood [affective] disorders	0.756	0.244	0.000
L40.1 Generalised pustular psoriasis	0.750	0.250	0.000
F30 Manic episode	0.739	0.261	0.000
F41.9 Anxiety disorder, unspecified	0.736	0.264	0.000
F41.2 Mixed anxiety and depressive disorder	0.731	0.269	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.716	0.284	0.000
F44 Dissociative [conversion] disorders	0.715	0.285	0.000
F30.0 Hypomania	0.710	0.290	0.000
F43 Reaction to severe stress, and adjustment disorders	0.701	0.299	0.000
L40.3 Pustulosis palmaris et plantaris	0.699	0.300	0.000
L40-L45 Papulosquamous disorders	0.693	0.307	0.000
K50.9 Crohn's disease, unspecified	0.693	0.307	0.000
K50 Crohn's disease [regional enteritis]	0.691	0.309	0.000
F33 Recurrent depressive disorder	0.689	0.311	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.678	0.322	0.000
F60-F69 Disorders of adult personality and behaviour	0.677	0.323	0.000
F01 Vascular dementia	0.677	0.323	0.000
F45 Somatoform disorders	0.676	0.324	0.000
K50.1 Crohn's disease of large intestine	0.662	0.338	0.000
K50.0 Crohn's disease of small intestine	0.653	0.347	0.000
F30.9 Manic episode, unspecified	0.653	0.347	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.643	0.357	0.000
K50.8 Other Crohn's disease	0.642	0.358	0.000
F43.0 Acute stress reaction	0.642	0.358	0.000
F01.9 Vascular dementia, unspecified	0.639	0.361	0.000
E11.9 Without complications	0.636	0.364	0.000
F60 Specific personality disorders	0.633	0.367	0.000
F80-F89 Disorders of psychological development	0.632	0.368	0.000
K90 Intestinal malabsorption	0.010	0.370	0.619
F44.5 Dissociative convulsions	0.623	0.377	0.000
F33.9 Recurrent depressive disorder, unspecified	0.620	0.380	0.000
H71 Cholesteatoma of middle ear	0.619	0.381	0.000
F45.8 Other somatoform disorders	0.615	0.385	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.610	0.390	0.000
E78.0 Pure hypercholesterolaemia	0.609	0.391	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.607	0.393	0.000
F43.2 Adjustment disorders	0.606	0.394	0.000
E11 Non-insulin-dependent diabetes mellitus	0.605	0.395	0.000
F06.7 Mild cognitive disorder	0.602	0.398	0.000
F70-F79 Mental retardation	0.599	0.401	0.000
H65-H75 Diseases of middle ear and mastoid	0.598	0.402	0.000
F41.3 Other mixed anxiety disorders	0.592	0.408	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.589	0.411	0.000
E10-E14 Diabetes mellitus	0.588	0.412	0.000
E70-E90 Metabolic disorders	0.586	0.414	0.000
F60.3 Emotionally unstable personality disorder	0.583	0.417	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.581	0.419	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.578	0.422	0.000
# Top node	0.575	0.425	0.000
Chapter VIII Diseases of the ear and mastoid process	0.570	0.430	0.000
F39 Unspecified mood [affective] disorder	0.568	0.432	0.000
F99-F99 Unspecified mental disorder	0.568	0.432	0.000
E85 Amyloidosis	0.565	0.435	0.000
F60.9 Personality disorder, unspecified	0.562	0.438	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.560	0.440	0.000
H73 Other disorders of tympanic membrane	0.555	0.445	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.555	0.445	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.552	0.448	0.000
Y57 Other and unspecified drugs and medicaments	0.548	0.452	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.545	0.455	0.000
F38 Other mood [affective] disorders	0.542	0.458	0.000
Y40 Systemic antibiotics	0.542	0.458	0.000
F44.4 Dissociative motor disorders	0.538	0.462	0.000
L05 Pilonidal cyst	0.538	0.462	0.000
Y57.9 Drug or medicament, unspecified	0.533	0.467	0.000
M07.3 Other psoriatic arthropathies	0.533	0.467	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.532	0.468	0.000
L05.0 Pilonidal cyst with abscess	0.532	0.468	0.000
F51 Nonorganic sleep disorders	0.532	0.468	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.531	0.469	0.000
F01.1 Multi-infarct dementia	0.530	0.470	0.000
F34 Persistent mood [affective] disorders	0.530	0.470	0.000
F30.8 Other manic episodes	0.530	0.470	0.000
F30.1 Mania without psychotic symptoms	0.530	0.470	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.523	0.477	0.000
F84 Pervasive developmental disorders	0.522	0.478	0.000
E11.4 With neurological complications	0.522	0.478	0.000
Chapter XX External causes of morbidity and mortality	0.520	0.480	0.000
F30.2 Mania with psychotic symptoms	0.518	0.482	0.000
F00 Dementia in Alzheimer's disease	0.515	0.485	0.000
E85.9 Amyloidosis, unspecified	0.514	0.486	0.000
H73.8 Other specified disorders of tympanic membrane	0.514	0.486	0.000
E20-E35 Disorders of other endocrine glands	0.514	0.486	0.000
F09 Unspecified organic or symptomatic mental disorder	0.514	0.486	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.514	0.486	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.005	0.486	0.509
F44.8 Other dissociative [conversion] disorders	0.513	0.487	0.000
F44.7 Mixed dissociative [conversion] disorders	0.513	0.487	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.513	0.487	0.000
F44.3 Trance and possession disorders	0.513	0.487	0.000
F44.2 Dissociative stupor	0.513	0.487	0.000
F44.1 Dissociative fugue	0.513	0.487	0.000
F44.0 Dissociative amnesia	0.513	0.487	0.000
F43.9 Reaction to severe stress, unspecified	0.509	0.491	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.508	0.492	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.507	0.493	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.506	0.494	0.000
Y57.8 Other drugs and medicaments	0.503	0.497	0.000
F43.8 Other reactions to severe stress	0.502	0.497	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.502	0.498	0.000
E85.4 Organ-limited amyloidosis	0.498	0.502	0.000
L44 Other papulosquamous disorders	0.497	0.503	0.000
L41 Parapsoriasis	0.497	0.503	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.497	0.503	0.000
F40 Phobic anxiety disorders	0.497	0.503	0.000
H66 Suppurative and unspecified otitis media	0.495	0.505	0.000
F48 Other neurotic disorders	0.495	0.505	0.000
F33.8 Other recurrent depressive disorders	0.494	0.506	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.494	0.506	0.000
Y52 Agents primarily affecting the cardiovascular system	0.492	0.508	0.000
Y40.9 Systemic antibiotic, unspecified	0.491	0.509	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.490	0.510	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.489	0.511	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.489	0.511	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.487	0.513	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.486	0.513	0.000
F06.5 Organic dissociative disorder	0.486	0.513	0.000
F06.4 Organic anxiety disorder	0.486	0.513	0.000
F06.3 Organic mood [affective] disorders	0.486	0.513	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.486	0.513	0.000
F06.1 Organic catatonic disorder	0.486	0.513	0.000
F06.0 Organic hallucinosis	0.486	0.513	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.486	0.514	0.000
F68 Other disorders of adult personality and behaviour	0.486	0.514	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.486	0.514	0.000
F65 Disorders of sexual preference	0.486	0.514	0.000
F63 Habit and impulse disorders	0.486	0.514	0.000
F61 Mixed and other personality disorders	0.486	0.514	0.000
F01.8 Other vascular dementia	0.485	0.515	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.485	0.515	0.000
F01.2 Subcortical vascular dementia	0.485	0.515	0.000
F01.0 Vascular dementia of acute onset	0.485	0.515	0.000
F45.4 Persistent somatoform pain disorder	0.485	0.515	0.000
F45.1 Undifferentiated somatoform disorder	0.485	0.515	0.000
F45.0 Somatisation disorder	0.485	0.515	0.000
K90.8 Other intestinal malabsorption	0.006	0.516	0.478
F60.5 Anankastic personality disorder	0.483	0.517	0.000
Y40.0 Penicillins	0.483	0.517	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.482	0.518	0.000
F45.2 Hypochondriacal disorder	0.480	0.520	0.000
F50 Eating disorders	0.479	0.521	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.477	0.523	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.475	0.525	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.475	0.525	0.000
F45.9 Somatoform disorder, unspecified	0.475	0.525	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.475	0.525	0.000
F79 Unspecified mental retardation	0.473	0.527	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.471	0.529	0.000
F45.3 Somatoform autonomic dysfunction	0.470	0.530	0.000
E89.3 Postprocedural hypopituitarism	0.470	0.530	0.000
F42 Obsessive-compulsive disorder	0.469	0.531	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.468	0.532	0.000
F60.0 Paranoid personality disorder	0.468	0.532	0.000
E88 Other metabolic disorders	0.467	0.533	0.000
E89.1 Postprocedural hypoinsulinaemia	0.465	0.535	0.000
F81 Specific developmental disorders of scholastic skills	0.464	0.536	0.000
L42 Pityriasis rosea	0.463	0.537	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.462	0.538	0.000
M07 Psoriatic and enteropathic arthropathies	0.462	0.538	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.461	0.539	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.461	0.539	0.000
F55 Abuse of non-dependence-producing substances	0.461	0.539	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.461	0.539	0.000
Y40.3 Macrolides	0.461	0.539	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.461	0.539	0.000
E26 Hyperaldosteronism	0.461	0.539	0.000
H66.3 Other chronic suppurative otitis media	0.460	0.540	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.460	0.540	0.000
E11.2 With renal complications	0.459	0.541	0.000
F80 Specific developmental disorders of speech and language	0.457	0.543	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.456	0.544	0.000
F41.1 Generalised anxiety disorder	0.455	0.545	0.000
F60.8 Other specific personality disorders	0.454	0.546	0.000
F60.4 Histrionic personality disorder	0.454	0.546	0.000
F60.2 Dissocial personality disorder	0.454	0.546	0.000
F60.1 Schizoid personality disorder	0.454	0.546	0.000
F89 Unspecified disorder of psychological development	0.453	0.547	0.000
F88 Other disorders of psychological development	0.453	0.547	0.000
F83 Mixed specific developmental disorders	0.453	0.547	0.000
F82 Specific developmental disorder of motor function	0.453	0.547	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.452	0.548	0.000
K90.3 Pancreatic steatorrhoea	0.008	0.548	0.444
K90.2 Blind loop syndrome, not elsewhere classified	0.008	0.548	0.444
K90.1 Tropical sprue	0.008	0.548	0.444
E85.3 Secondary systemic amyloidosis	0.450	0.550	0.000
T91 Sequelae of injuries of neck and trunk	0.450	0.550	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.449	0.551	0.000
S40-S49 Injuries to the shoulder and upper arm	0.449	0.551	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.449	0.551	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.449	0.551	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.449	0.551	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.448	0.552	0.000
E11.0 With coma	0.447	0.553	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.447	0.553	0.000
W50-W64 Exposure to animate mechanical forces	0.446	0.554	0.000
F84.5 Asperger's syndrome	0.445	0.555	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.445	0.555	0.000
H74 Other disorders of middle ear and mastoid	0.445	0.555	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.444	0.556	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.444	0.556	0.000
E11.3 With ophthalmic complications	0.444	0.556	0.000
K90.9 Intestinal malabsorption, unspecified	0.005	0.557	0.439
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.443	0.557	0.000
T91.1 Sequelae of fracture of spine	0.442	0.558	0.000
F41.8 Other specified anxiety disorders	0.441	0.559	0.000
Y59 Other and unspecified vaccines and biological substances	0.441	0.559	0.000
F02 Dementia in other diseases classified elsewhere	0.441	0.559	0.000
H68 Eustachian salpingitis and obstruction	0.440	0.559	0.000
F69 Unspecified disorder of adult personality and behaviour	0.440	0.560	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.440	0.560	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.439	0.560	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.439	0.561	0.000
Q80-Q89 Other congenital malformations	0.439	0.561	0.000
F31 Bipolar affective disorder	0.437	0.563	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.436	0.564	0.000
E11.7 With multiple complications	0.433	0.566	0.000
V10-V19 Pedal cyclist injured in transport accident	0.433	0.567	0.000
E21.3 Hyperparathyroidism, unspecified	0.432	0.568	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.432	0.568	0.000
H72 Perforation of tympanic membrane	0.431	0.569	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.431	0.569	0.000
S43.0 Dislocation of shoulder joint	0.430	0.570	0.000
E78.6 Lipoprotein deficiency	0.430	0.570	0.000
F78 Other mental retardation	0.429	0.571	0.000
F73 Profound mental retardation	0.429	0.571	0.000
F72 Severe mental retardation	0.429	0.571	0.000
F71 Moderate mental retardation	0.429	0.571	0.000
F70 Mild mental retardation	0.429	0.571	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.429	0.571	0.000
H67 Otitis media in diseases classified elsewhere	0.429	0.571	0.000
E65-E68 Obesity and other hyperalimentation	0.428	0.571	0.000
E79 Disorders of purine and pyrimidine metabolism	0.428	0.572	0.000
Y57.6 Other diagnostic agents	0.428	0.572	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.427	0.572	0.000
T91.3 Sequelae of injury of spinal cord	0.425	0.575	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.425	0.575	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.423	0.577	0.000
Y40.7 Antifungal antibiotics, systemically used	0.423	0.577	0.000
F51.5 Nightmares	0.423	0.577	0.000
E20 Hypoparathyroidism	0.422	0.578	0.000
Y00-Y09 Assault	0.422	0.578	0.000
E12 Malnutrition-related diabetes mellitus	0.422	0.578	0.000
F51.0 Nonorganic insomnia	0.421	0.579	0.000
Y44 Agents primarily affecting blood constituents	0.421	0.579	0.000
E23 Hypofunction and other disorders of pituitary gland	0.421	0.579	0.000
E77 Disorders of glycoprotein metabolism	0.420	0.580	0.000
E76 Disorders of glycosaminoglycan metabolism	0.420	0.580	0.000
E72 Other disorders of amino-acid metabolism	0.420	0.580	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.420	0.580	0.000
E70 Disorders of aromatic amino-acid metabolism	0.420	0.580	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.420	0.580	0.000
L03.3 Cellulitis of trunk	0.420	0.580	0.000
F99 Mental disorder, not otherwise specified	0.420	0.580	0.000
T36 Poisoning by systemic antibiotics	0.418	0.582	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.417	0.583	0.000
E13 Other specified diabetes mellitus	0.417	0.583	0.000
Y40.4 Tetracyclines	0.417	0.583	0.000
L03 Cellulitis	0.416	0.584	0.000
W75-W84 Other accidental threats to breathing	0.416	0.584	0.000
Y49.5 Other antipsychotics and neuroleptics	0.416	0.584	0.000
E78.3 Hyperchylomicronaemia	0.414	0.586	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.412	0.588	0.000
L04 Acute lymphadenitis	0.411	0.588	0.000
Y10-Y34 Event of undetermined intent	0.411	0.589	0.000
E26.0 Primary hyperaldosteronism	0.411	0.589	0.000
M05-M14 Inflammatory polyarthropathies	0.411	0.589	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.410	0.590	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.410	0.590	0.000
X00-X09 Exposure to smoke, fire and flames	0.409	0.591	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.407	0.592	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.407	0.593	0.000
L05.9 Pilonidal cyst without abscess	0.407	0.593	0.000
E14 Unspecified diabetes mellitus	0.407	0.593	0.000
S00-S09 Injuries to the head	0.406	0.594	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.406	0.594	0.000
F64 Gender identity disorders	0.405	0.594	0.000
E85.8 Other amyloidosis	0.405	0.595	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.405	0.595	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.405	0.595	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.405	0.595	0.000
Y52.1 Calcium-channel blockers	0.405	0.595	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.404	0.596	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.403	0.597	0.000
V01-V09 Pedestrian injured in transport accident	0.403	0.597	0.000
Y40.6 Rifamycins	0.402	0.598	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.402	0.598	0.000
S32 Fracture of lumbar spine and pelvis	0.402	0.598	0.000
V90-V94 Water transport accidents	0.402	0.598	0.000
W55 Bitten or struck by other mammals	0.401	0.599	0.000
T88.4 Failed or difficult intubation	0.401	0.599	0.000
E11.6 With other specified complications	0.400	0.600	0.000
S06 Intracranial injury	0.399	0.601	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.399	0.601	0.000
H73.1 Chronic myringitis	0.398	0.602	0.000
H73.0 Acute myringitis	0.398	0.602	0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.398	0.602	0.000
F95 Tic disorders	0.398	0.602	0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence	0.398	0.602	0.000
F93 Emotional disorders with onset specific to childhood	0.398	0.602	0.000
F92 Mixed disorders of conduct and emotions	0.398	0.602	0.000
F91 Conduct disorders	0.398	0.602	0.000
F90 Hyperkinetic disorders	0.398	0.602	0.000
Y58 Bacterial vaccines	0.398	0.602	0.000
E89.4 Postprocedural ovarian failure	0.398	0.602	0.000
T50.8 Diagnostic agents	0.397	0.602	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.396	0.604	0.000
F60.7 Dependent personality disorder	0.395	0.605	0.000
Y46.2 Hydantoin derivatives	0.395	0.605	0.000
E89.2 Postprocedural hypoparathyroidism	0.394	0.606	0.000
Y57.7 Vitamins, not elsewhere classified	0.393	0.607	0.000
Y57.4 Pharmaceutical excipients	0.393	0.607	0.000
Y57.3 Alcohol deterrents	0.393	0.607	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.393	0.607	0.000
Y57.1 Lipotropic drugs	0.393	0.607	0.000
Y57.0 Appetite depressants [anorectics]	0.393	0.607	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.393	0.607	0.000
E80.2 Other porphyria	0.392	0.607	0.000
E40-E46 Malnutrition	0.392	0.608	0.000
E74 Other disorders of carbohydrate metabolism	0.392	0.608	0.000
Y49.2 Other and unspecified antidepressants	0.391	0.609	0.000
L00 Staphylococcal scalded skin syndrome	0.391	0.609	0.000
S40 Superficial injury of shoulder and upper arm	0.391	0.609	0.000
E78.1 Pure hyperglyceridaemia	0.390	0.610	0.000
E80.6 Other disorders of bilirubin metabolism	0.390	0.610	0.000
V70-V79 Bus occupant injured in transport accident	0.389	0.611	0.000
Q50-Q56 Congenital malformations of genital organs	0.389	0.611	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.389	0.611	0.000
F38.8 Other specified mood [affective] disorders	0.388	0.611	0.000
F38.1 Other recurrent mood [affective] disorders	0.388	0.611	0.000
F38.0 Other single mood [affective] disorders	0.388	0.611	0.000
Y40.2 Chloramphenicol group	0.388	0.611	0.000
E84 Cystic fibrosis	0.388	0.611	0.000
E11.1 With ketoacidosis	0.388	0.612	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.388	0.612	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.388	0.612	0.000
S06.5 Traumatic subdural haemorrhage	0.388	0.612	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.388	0.612	0.000
F40.2 Specific (isolated) phobias	0.388	0.612	0.000
V98-V99 Other and unspecified transport accidents	0.386	0.613	0.000
H66.4 Suppurative otitis media, unspecified	0.384	0.615	0.000
Y46.5 Valproic acid	0.384	0.616	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.384	0.616	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.384	0.616	0.000
F62.9 Enduring personality change, unspecified	0.384	0.616	0.000
S02 Fracture of skull and facial bones	0.384	0.616	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.383	0.617	0.000
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)	0.383	0.617	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.383	0.617	0.000
Y40.5 Aminoglycosides	0.382	0.617	0.000
M07.38 Other psoriatic arthropathies (Other)	0.382	0.618	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.382	0.618	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.382	0.618	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.382	0.618	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.381	0.619	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.381	0.619	0.000
F51.8 Other nonorganic sleep disorders	0.381	0.619	0.000
F51.4 Sleep terrors [night terrors]	0.381	0.619	0.000
F51.3 Sleepwalking [somnambulism]	0.381	0.619	0.000
F51.2 Nonorganic disorder of the sleep-wake schedule	0.381	0.619	0.000
F51.1 Nonorganic hypersomnia	0.381	0.619	0.000
S32.4 Fracture of acetabulum	0.381	0.619	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.381	0.619	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.381	0.619	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.381	0.619	0.000
E89.5 Postprocedural testicular hypofunction	0.381	0.619	0.000
E34 Other endocrine disorders	0.380	0.620	0.000
F32 Depressive episode	0.380	0.620	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.380	0.620	0.000
F34.8 Other persistent mood [affective] disorders	0.380	0.620	0.000
F34.0 Cyclothymia	0.380	0.620	0.000
E88.8 Other specified metabolic disorders	0.380	0.620	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.380	0.620	0.000
E65 Localised adiposity	0.379	0.621	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.378	0.622	0.000
V95-V97 Air and space transport accidents	0.378	0.622	0.000
E25 Adrenogenital disorders	0.377	0.623	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.376	0.624	0.000
T36.0 Penicillins	0.376	0.624	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.375	0.625	0.000
E78.2 Mixed hyperlipidaemia	0.375	0.625	0.000
Y46.7 Anti-Parkinsonism drugs	0.375	0.625	0.000
H70 Mastoiditis and related conditions	0.375	0.625	0.000
F84.9 Pervasive developmental disorder, unspecified	0.375	0.625	0.000
F84.8 Other pervasive developmental disorders	0.375	0.625	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.375	0.625	0.000
F84.3 Other childhood disintegrative disorder	0.375	0.625	0.000
F84.2 Rett's syndrome	0.375	0.625	0.000
F84.1 Atypical autism	0.375	0.625	0.000
M11 Other crystal arthropathies	0.375	0.625	0.000
E21.4 Other specified disorders of parathyroid gland	0.374	0.626	0.000
Y35-Y36 Legal intervention and operations of war	0.373	0.627	0.000
X85-X99 Assault	0.373	0.627	0.000
X30-X39 Exposure to forces of nature	0.373	0.627	0.000
W65-W74 Accidental drowning and submersion	0.373	0.627	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.373	0.627	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.373	0.627	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.373	0.627	0.000
F84.0 Childhood autism	0.373	0.627	0.000
E21.2 Other hyperparathyroidism	0.373	0.627	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.373	0.627	0.000
S06.2 Diffuse brain injury	0.372	0.628	0.000
W20-W49 Exposure to inanimate mechanical forces	0.370	0.630	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.369	0.630	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.369	0.631	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.369	0.631	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.368	0.631	0.000
E32 Diseases of thymus	0.368	0.631	0.000
E31 Polyglandular dysfunction	0.368	0.631	0.000
E30 Disorders of puberty, not elsewhere classified	0.368	0.631	0.000
F40.8 Other phobic anxiety disorders	0.368	0.631	0.000
E78.8 Other disorders of lipoprotein metabolism	0.368	0.632	0.000
F34.1 Dysthymia	0.368	0.632	0.000
L43 Lichen planus	0.368	0.632	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.368	0.632	0.000
Y46.6 Other and unspecified antiepileptics	0.367	0.633	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.367	0.633	0.000
S32.40 Fracture of acetabulum (closed)	0.367	0.633	0.000
Y57.5 X-ray contrast media	0.367	0.633	0.000
E11.5 With peripheral circulatory complications	0.367	0.633	0.000
Q60-Q64 Congenital malformations of the urinary system	0.366	0.634	0.000
L58 Radiodermatitis	0.364	0.635	0.000
L10-L14 Bullous disorders	0.364	0.636	0.000
F50.2 Bulimia nervosa	0.364	0.636	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.364	0.636	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.363	0.636	0.000
F62.8 Other enduring personality changes	0.363	0.637	0.000
F62.1 Enduring personality change after psychiatric illness	0.363	0.637	0.000
F62.0 Enduring personality change after catastrophic experience	0.363	0.637	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.363	0.637	0.000
Q82 Other congenital malformations of skin	0.363	0.637	0.000
Q35-Q37 Cleft lip and cleft palate	0.363	0.637	0.000
Y43 Primarily systemic agents	0.362	0.638	0.000
F50.9 Eating disorder, unspecified	0.361	0.639	0.000
F31.8 Other bipolar affective disorders	0.361	0.639	0.000
S02.4 Fracture of malar and maxillary bones	0.361	0.639	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.360	0.640	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.360	0.640	0.000
F07.1 Postencephalitic syndrome	0.360	0.640	0.000
E26.9 Hyperaldosteronism, unspecified	0.360	0.640	0.000
E80.1 Porphyria cutanea tarda	0.359	0.640	0.000
F60.6 Anxious [avoidant] personality disorder	0.359	0.640	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.358	0.641	0.000
E28 Ovarian dysfunction	0.358	0.642	0.000
Q44.6 Cystic disease of liver	0.358	0.642	0.000
Y59.3 Immunoglobulin	0.357	0.642	0.000
S10-S19 Injuries to the neck	0.358	0.642	0.000
H66.0 Acute suppurative otitis media	0.357	0.643	0.000
F07.0 Organic personality disorder	0.357	0.643	0.000
E20.9 Hypoparathyroidism, unspecified	0.357	0.643	0.000
L41.9 Parapsoriasis, unspecified	0.357	0.643	0.000
L41.8 Other parapsoriasis	0.357	0.643	0.000
L41.5 Retiform parapsoriasis	0.357	0.643	0.000
L41.4 Large plaque parapsoriasis	0.357	0.643	0.000
L41.3 Small plaque parapsoriasis	0.357	0.643	0.000
L41.2 Lymphomatoid papulosis	0.357	0.643	0.000
L41.1 Pityriasis lichenoides chronica	0.357	0.643	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.357	0.643	0.000
L44.9 Papulosquamous disorder, unspecified	0.357	0.643	0.000
L44.8 Other specified papulosquamous disorders	0.357	0.643	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.357	0.643	0.000
L44.3 Lichen ruber moniliformis	0.357	0.643	0.000
L44.2 Lichen striatus	0.357	0.643	0.000
L44.1 Lichen nitidus	0.357	0.643	0.000
L44.0 Pityriasis rubra pilaris	0.357	0.643	0.000
F40.1 Social phobias	0.356	0.644	0.000
Q38.7 Pharyngeal pouch	0.356	0.644	0.000
E87.6 Hypokalaemia	0.356	0.644	0.000
Y46.4 Iminostilbenes	0.355	0.645	0.000
F48.8 Other specified neurotic disorders	0.355	0.645	0.000
F48.1 Depersonalisation-derealisation syndrome	0.355	0.645	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.355	0.645	0.000
L01 Impetigo	0.355	0.645	0.000
W55.0 Home	0.355	0.645	0.000
E73 Lactose intolerance	0.355	0.645	0.000
E87.2 Acidosis	0.355	0.645	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.354	0.646	0.000
M11.2 Other chondrocalcinosis	0.354	0.646	0.000
F52.2 Failure of genital response	0.354	0.646	0.000
E14.4 With neurological complications	0.353	0.647	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.353	0.647	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.353	0.647	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.353	0.647	0.000
Y52.7 Peripheral vasodilators	0.353	0.647	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.353	0.647	0.000
F07.2 Postconcussional syndrome	0.352	0.648	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.352	0.648	0.000
T50.4 Drugs affecting uric acid metabolism	0.352	0.648	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.351	0.649	0.000
T33-T35 Frostbite	0.351	0.649	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations