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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1052486
log Bayes Factor = 138.645
Chromosome 6   position 31,610,686  (GRCh37) Explore rs1052486 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.996 0.004 0.000
E10.2 With renal complications
0.000 0.005 0.995
E10.1 With ketoacidosis
0.000 0.006 0.994
K90 Intestinal malabsorption
0.000 0.016 0.984
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.030 0.970
E50-E64 Other nutritional deficiencies
0.000 0.030 0.970
K90.9 Intestinal malabsorption, unspecified
0.000 0.033 0.967
E14 Unspecified diabetes mellitus
0.000 0.036 0.964
E16 Other disorders of pancreatic internal secretion
0.000 0.051 0.949
E10.4 With neurological complications
0.000 0.060 0.940
E53 Deficiency of other B group vitamins
0.000 0.075 0.925
E16.2 Hypoglycaemia, unspecified
0.000 0.082 0.918
E10.5 With peripheral circulatory complications
0.000 0.093 0.907
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.098 0.902
E14.3 With ophthalmic complications
0.000 0.103 0.897
E55 Vitamin D deficiency
0.000 0.130 0.870
E10.0 With coma
0.000 0.130 0.870
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.130 0.870
E06 Thyroiditis
0.000 0.135 0.865
L40.9 Psoriasis, unspecified
0.859 0.141 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.152 0.848
E14.6 With other specified complications
0.000 0.164 0.836
E53.9 Vitamin B deficiency, unspecified
0.000 0.166 0.834
E53.8 Deficiency of other specified B group vitamins
0.000 0.168 0.832
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.177 0.823
T36-T50 Poisoning by drugs, medicaments and biological substances
0.823 0.177 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.182 0.818
E27.1 Primary adrenocortical insufficiency
0.000 0.184 0.816
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.807 0.193 0.000
T39.1 4-Aminophenol derivatives
0.802 0.198 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.800 0.200 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.799 0.201 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.201 0.799
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.792 0.208 0.000
E27 Other disorders of adrenal gland
0.000 0.220 0.779
E14.2 Withrenal complications
0.000 0.221 0.779
E20-E35 Disorders of other endocrine glands
0.000 0.222 0.778
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.775 0.225 0.000
K90.8 Other intestinal malabsorption
0.000 0.229 0.771
E14.1 With ketoacidosis
0.000 0.232 0.768
R04.0 Epistaxis
0.768 0.232 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.766 0.234 0.000
E06.9 Thyroiditis, unspecified
0.000 0.235 0.765
E14.5 With peripheral circulatory complications
0.000 0.245 0.755
E13 Other specified diabetes mellitus
0.000 0.249 0.751
E14.8 With unspecified complications
0.000 0.253 0.747
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.257 0.743
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.743 0.257 0.000
E10.7 With multiple complications
0.000 0.258 0.742
T43.5 Other and unspecified antipsychotics and neuroleptics
0.733 0.267 0.000
E40-E46 Malnutrition
0.000 0.269 0.731
R31 Unspecified haematuria
0.728 0.272 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.272 0.728
E51 Thiamine deficiency
0.000 0.274 0.726
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.288 0.712
T43.2 Other and unspecified antidepressants
0.710 0.290 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.708 0.292 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.295 0.705
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.295 0.705
K90.1 Tropical sprue
0.000 0.295 0.705
E61 Deficiency of other nutrient elements
0.000 0.296 0.704
T46.4 Angiotensin-converting-enzyme inhibitors
0.703 0.297 0.000
E14.4 With neurological complications
0.000 0.299 0.701
E05.8 Other thyrotoxicosis
0.000 0.299 0.701
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.699 0.301 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.304 0.696
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.304 0.695
E63 Other nutritional deficiencies
0.000 0.304 0.695
E50 Vitamin A deficiency
0.000 0.304 0.695
E60 Dietary zinc deficiency
0.000 0.304 0.695
E59 Dietary selenium deficiency
0.000 0.304 0.695
E52 Niacin deficiency [pellagra]
0.000 0.304 0.695
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.695 0.305 0.000
E14.7 With multiple complications
0.000 0.309 0.691
E14.0 With coma
0.000 0.309 0.691
E58 Dietary calcium deficiency
0.000 0.312 0.688
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.319 0.680
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.319 0.680
E16.4 Abnormal secretion of gastrin
0.000 0.319 0.680
E16.3 Increased secretion of glucagon
0.000 0.319 0.680
T39.0 Salicylates
0.680 0.320 0.000
E06.3 Autoimmune thyroiditis
0.000 0.326 0.674
E53.1 Pyridoxine deficiency
0.000 0.337 0.663
E53.0 Riboflavin deficiency
0.000 0.337 0.663
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.353 0.647
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.647 0.353 0.000
E54 Ascorbic acid deficiency
0.000 0.358 0.642
T46.5 Other antihypertensive drugs, not elsewhere classified
0.641 0.359 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.640 0.360 0.000
E24 Cushing's syndrome
0.000 0.365 0.635
E56 Other vitamin deficiencies
0.000 0.366 0.634
T43.3 Phenothiazine antipsychotics and neuroleptics
0.625 0.375 0.000
E55.0 Rickets, active
0.000 0.376 0.624
T45.0 Antiallergic and antiemetic drugs
0.622 0.378 0.000
E06.4 Drug-induced thyroiditis
0.000 0.380 0.620
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.380 0.620
E06.0 Acute thyroiditis
0.000 0.380 0.620
E06.5 Other chronic thyroiditis
0.000 0.387 0.613
E20 Hypoparathyroidism
0.000 0.391 0.609
E10.8 With unspecified complications
0.000 0.394 0.605
G36 Other acute disseminated demyelination
0.000 0.395 0.605
E61.2 Magnesium deficiency
0.000 0.397 0.603
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.601 0.399 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.600 0.400 0.000
T43.6 Psychostimulants with abuse potential
0.600 0.400 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.600 0.400 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.599 0.401 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.598 0.402 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.596 0.404 0.000
T50.4 Drugs affecting uric acid metabolism
0.595 0.405 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.592 0.408 0.000
E13.9 Without complications
0.000 0.409 0.591
T41 Poisoning by anaesthetics and therapeutic gases
0.590 0.410 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.413 0.586
G37.4 Subacute necrotising myelitis
0.000 0.413 0.586
G37.2 Central pontine myelinolysis
0.000 0.413 0.586
G37.1 Central demyelination of corpus callosum
0.000 0.413 0.586
G37.0 Diffuse sclerosis
0.000 0.413 0.586
T39.4 Antirheumatics, not elsewhere classified
0.578 0.422 0.000
T39.2 Pyrazolone derivatives
0.578 0.422 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.423 0.577
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.576 0.424 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.574 0.426 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.574 0.426 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.574 0.426 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.574 0.426 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.574 0.426 0.000
T44.0 Anticholinesterase agents
0.574 0.426 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.573 0.427 0.000
T46.7 Peripheral vasodilators
0.573 0.427 0.000
E31 Polyglandular dysfunction
0.000 0.427 0.573
E06.1 Subacute thyroiditis
0.000 0.430 0.570
E27.2 Addisonian crisis
0.000 0.431 0.569
T43.9 Psychotropic drug, unspecified
0.568 0.432 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.568 0.432 0.000
T36 Poisoning by systemic antibiotics
0.564 0.436 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.439 0.561
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.560 0.440 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.441 0.559
E27.0 Other adrenocortical overactivity
0.000 0.441 0.559
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.442 0.557
E32 Diseases of thymus
0.000 0.442 0.557
E30 Disorders of puberty, not elsewhere classified
0.000 0.442 0.557
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.558 0.442 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.557 0.443 0.000
E51.2 Wernicke's encephalopathy
0.000 0.449 0.551
T50.7 Analeptics and opioid receptor antagonists
0.549 0.450 0.000
T50.5 Appetite depressants
0.549 0.450 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.549 0.450 0.000
T50.1 Loop [high-ceiling] diuretics
0.549 0.450 0.000
T50.0 Mineralocorticoids and their antagonists
0.549 0.450 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.549 0.451 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.544 0.455 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.461 0.539
E13.8 With unspecified complications
0.000 0.461 0.539
E13.7 With multiple complications
0.000 0.461 0.539
E13.6 With other specified complications
0.000 0.461 0.539
E13.5 With peripheral circulatory complications
0.000 0.461 0.539
E13.4 With neurological complications
0.000 0.461 0.539
E13.2 With renal complications
0.000 0.461 0.539
E13.1 With ketoacidosis
0.000 0.461 0.539
E13.0 With coma
0.000 0.461 0.539
E24.0 Pituitary-dependent Cushing's disease
0.000 0.462 0.538
E25 Adrenogenital disorders
0.000 0.462 0.537
E11.5 With peripheral circulatory complications
0.000 0.470 0.530
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.476 0.524
E45 Retarded development following protein-energy malnutrition
0.000 0.476 0.524
E43 Unspecified severe protein-energy malnutrition
0.000 0.476 0.524
E42 Marasmic kwashiorkor
0.000 0.476 0.524
E41 Nutritional marasmus
0.000 0.476 0.524
E40 Kwashiorkor
0.000 0.476 0.524
E51.9 Thiamine deficiency, unspecified
0.000 0.479 0.521
E51.8 Other manifestations of thiamine deficiency
0.000 0.479 0.521
E51.1 Beriberi
0.000 0.479 0.521
L40 Psoriasis
0.519 0.481 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.519 0.481 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.517 0.483 0.000
E13.3 With ophthalmic complications
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.510 0.490 0.000
T45.5 Anticoagulants
0.510 0.490 0.000
E16.1 Other hypoglycaemia
0.000 0.493 0.507
E61.9 Deficiency of nutrient element, unspecified
0.000 0.495 0.504
E61.8 Deficiency of other specified nutrient elements
0.000 0.495 0.504
E61.7 Deficiency of multiple nutrient elements
0.000 0.495 0.504
E61.6 Vanadium deficiency
0.000 0.495 0.504
E61.5 Molybdenum deficiency
0.000 0.495 0.504
E61.4 Chromium deficiency
0.000 0.495 0.504
E61.3 Manganese deficiency
0.000 0.495 0.504
E61.0 Copper deficiency
0.000 0.495 0.504
T43.4 Butyrophenone and thioxanthene neuroleptics
0.503 0.497 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.497 0.503
T38.1 Thyroid hormones and substitutes
0.502 0.498 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.501 0.499 0.000
T45.8 Other primarily systemic and haematological agents
0.501 0.499 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.501 0.499 0.000
T45.6 Fibrinolysis-affecting drugs
0.501 0.499 0.000
T45.4 Iron and its compounds
0.501 0.499 0.000
T45.3 Enzymes, not elsewhere classified
0.501 0.499 0.000
T38.0 Glucocorticoids and synthetic analogues
0.499 0.501 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.501 0.499
E50.8 Other manifestations of vitamin A deficiency
0.000 0.501 0.499
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.501 0.499
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.501 0.499
E50.5 Vitamin A deficiency with night blindness
0.000 0.501 0.499
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.501 0.499
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.501 0.499
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.501 0.499
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.501 0.499
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.501 0.499
E63.9 Nutritional deficiency, unspecified
0.000 0.501 0.499
E63.8 Other specified nutritional deficiencies
0.000 0.501 0.499
E63.1 Imbalance of constituents of food intake
0.000 0.501 0.499
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.501 0.499
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.501 0.499
E64.8 Sequelae of other nutritional deficiencies
0.000 0.501 0.499
E64.3 Sequelae of rickets
0.000 0.501 0.499
E64.2 Sequelae of vitamin C deficiency
0.000 0.501 0.499
E64.1 Sequelae of vitamin A deficiency
0.000 0.501 0.499
E64.0 Sequelae of protein-energy malnutrition
0.000 0.501 0.499
T38.9 Other and unspecified hormone antagonists
0.499 0.501 0.000
T38.7 Androgens and anabolic congeners
0.499 0.501 0.000
T38.5 Other oestrogens and progestogens
0.499 0.501 0.000
T38.4 Oral contraceptives
0.499 0.501 0.000
T38.2 Antithyroid drugs
0.499 0.501 0.000
T46.1 Calcium-channel blockers
0.493 0.507 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.492 0.508 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.508 0.491
E20.9 Hypoparathyroidism, unspecified
0.000 0.512 0.488
E34 Other endocrine disorders
0.000 0.513 0.487
E11.4 With neurological complications
0.000 0.513 0.487
E27.9 Disorder of adrenal gland, unspecified
0.000 0.515 0.485
T50.8 Diagnostic agents
0.483 0.517 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.482 0.518 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.477 0.523 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.474 0.526 0.000
T45.2 Vitamins, not elsewhere classified
0.470 0.530 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.469 0.531 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.545 0.455
E24.3 Ectopic ACTH syndrome
0.000 0.545 0.455
E24.1 Nelson's syndrome
0.000 0.545 0.455
E56.9 Vitamin deficiency, unspecified
0.000 0.545 0.455
E56.8 Deficiency of other vitamins
0.000 0.545 0.455
E56.0 Deficiency of vitamin E
0.000 0.545 0.455
T47.2 Stimulant laxatives
0.451 0.549 0.000
E11.1 With ketoacidosis
0.000 0.550 0.450
E11.0 With coma
0.000 0.557 0.443
E24.8 Other Cushing's syndrome
0.000 0.559 0.441
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.437 0.563 0.000
E20.8 Other hypoparathyroidism
0.000 0.563 0.437
E20.1 Pseudohypoparathyroidism
0.000 0.563 0.437
E20.0 Idiopathic hypoparathyroidism
0.000 0.563 0.437
G36.9 Acute disseminated demyelination, unspecified
0.000 0.566 0.434
G36.8 Other specified acute disseminated demyelination
0.000 0.566 0.434
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.566 0.434
L40.8 Other psoriasis
0.433 0.567 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.431 0.569 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.431 0.569 0.000
T47.7 Emetics
0.431 0.569 0.000
T47.5 Digestants
0.431 0.569 0.000
T47.3 Saline and osmotic laxatives
0.431 0.569 0.000
G36.0 Neuromyelitis optica [Devic]
0.000 0.570 0.430
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.427 0.573 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.574 0.426
E31.0 Autoimmune polyglandular failure
0.000 0.574 0.426
T49.9 Topical agent, unspecified
0.425 0.575 0.000
T49.8 Other topical agents
0.425 0.575 0.000
T49.7 Dental drugs, topically applied
0.425 0.575 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.425 0.575 0.000
T49.5 Ophthalmological drugs and preparations
0.425 0.575 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.425 0.575 0.000
T49.3 Emollients, demulcents and protectants
0.425 0.575 0.000
T49.2 Local astringents and local detergents
0.425 0.575 0.000
T49.1 Antipruritics
0.425 0.575 0.000
T41.5 Therapeutic gases
0.423 0.577 0.000
T41.4 Anaesthetic, unspecified
0.423 0.577 0.000
T41.3 Local anaesthetics
0.423 0.577 0.000
T41.2 Other and unspecified general anaesthetics
0.423 0.577 0.000
T41.1 Intravenous anaesthetics
0.423 0.577 0.000
T41.0 Inhaled anaesthetics
0.423 0.577 0.000
E11.6 With other specified complications
0.000 0.583 0.417
T47.4 Other laxatives
0.415 0.585 0.000
T47.0 Histamine H(2)-receptor antagonists
0.414 0.585 0.000
E07 Other disorders of thyroid
0.000 0.587 0.413
E31.9 Polyglandular dysfunction, unspecified
0.000 0.589 0.411
E31.8 Other polyglandular dysfunction
0.000 0.589 0.411
E31.1 Polyglandular hyperfunction
0.000 0.589 0.411
L40.0 Psoriasis vulgaris
0.406 0.594 0.000
T42.0 Hydantoin derivatives
0.405 0.595 0.000
E11.7 With multiple complications
0.000 0.595 0.405
T36.9 Systemic antibiotic, unspecified
0.404 0.596 0.000
T36.8 Other systemic antibiotics
0.404 0.596 0.000
T36.7 Antifungal antibiotics, systemically used
0.404 0.596 0.000
T36.6 Rifamycins
0.404 0.596 0.000
T36.5 Aminoglycosides
0.404 0.596 0.000
T36.4 Tetracyclines
0.404 0.596 0.000
T36.3 Macrolides
0.404 0.596 0.000
T36.2 Chloramphenicol group
0.404 0.596 0.000
L40.5 Arthropathic psoriasis
0.404 0.596 0.000
T42.3 Barbiturates
0.403 0.597 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.402 0.598 0.000
T37.5 Antiviral drugs
0.402 0.598 0.000
T37.4 Anthelminthics
0.402 0.598 0.000
T37.3 Other antiprotozoal drugs
0.402 0.598 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.402 0.598 0.000
T37.1 Antimycobacterial drugs
0.402 0.598 0.000
T37.0 Sulphonamides
0.402 0.598 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.600 0.400
E30.8 Other disorders of puberty
0.000 0.600 0.400
E30.1 Precocious puberty
0.000 0.600 0.400
E30.0 Delayed puberty
0.000 0.600 0.400
E32.9 Disease of thymus, unspecified
0.000 0.600 0.400
E32.8 Other diseases of thymus
0.000 0.600 0.400
E32.1 Abscess of thymus
0.000 0.600 0.400
E32.0 Persistent hyperplasia of thymus
0.000 0.600 0.400
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.600 0.400
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.600 0.400
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.600 0.400
E34.8 Other specified endocrine disorders
0.000 0.601 0.399
T47.6 Antidiarrhoeal drugs
0.396 0.603 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.604 0.396
E11.8 With unspecified complications
0.000 0.604 0.396
E56.1 Deficiency of vitamin K
0.000 0.606 0.394
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.390 0.609 0.000
T48.4 Expectorants
0.390 0.609 0.000
T48.3 Antitussives
0.390 0.609 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.390 0.609 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.390 0.609 0.000
T48.0 Oxytocic drugs
0.390 0.609 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.390 0.610 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.387 0.613 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.614 0.385
E25.8 Other adrenogenital disorders
0.000 0.614 0.385
T42.1 Iminostilbenes
0.382 0.618 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.624 0.376
E44.0 Moderate protein-energy malnutrition
0.000 0.624 0.376
T48.5 Anti-common-cold drugs
0.376 0.624 0.000
L40.4 Guttate psoriasis
0.376 0.624 0.000
L40.2 Acrodermatitis continua
0.372 0.627 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.372 0.627 0.000
T42.2 Succinimides and oxazolidinediones
0.372 0.627 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.372 0.628 0.000
E28 Ovarian dysfunction
0.000 0.633 0.367
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.635 0.365
T48.6 Antiasthmatics, not elsewhere classified
0.362 0.638 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.640 0.360
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.649 0.350
E34.5 Androgen resistance syndrome
0.000 0.650 0.349
E34.4 Constitutional tall stature
0.000 0.650 0.349
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.650 0.349
E34.1 Other hypersecretion of intestinal hormones
0.000 0.650 0.349
E29 Testicular dysfunction
0.001 0.662 0.338
T36.0 Penicillins
0.330 0.670 0.000
E26 Hyperaldosteronism
0.001 0.670 0.329
D25.9 Leiomyoma of uterus, unspecified
0.329 0.671 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.326 0.674 0.000
E61.1 Iron deficiency
0.000 0.675 0.325
E34.9 Endocrine disorder, unspecified
0.000 0.678 0.322
L40.1 Generalised pustular psoriasis
0.314 0.685 0.001
L40.3 Pustulosis palmaris et plantaris
0.312 0.687 0.001
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.313 0.687 0.000
E34.0 Carcinoid syndrome
0.000 0.691 0.309
E67 Other hyperalimentation
0.000 0.694 0.306
E68 Sequelae of hyperalimentation
0.000 0.694 0.306
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.700 0.300
E07.1 Dyshormogenetic goitre
0.000 0.703 0.296
E07.0 Hypersecretion of calcitonin
0.000 0.703 0.296
M35.0 Sicca syndrome [Sjogren]
0.000 0.710 0.290
F41.9 Anxiety disorder, unspecified
0.289 0.711 0.000
T42.4 Benzodiazepines
0.288 0.712 0.000
E22 Hyperfunction of pituitary gland
0.000 0.712 0.287
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.283 0.717 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.722 0.277
E28.9 Ovarian dysfunction, unspecified
0.000 0.737 0.263
E28.8 Other ovarian dysfunction
0.000 0.737 0.263
E28.1 Androgen excess
0.000 0.737 0.263
E28.0 Oestrogen excess
0.000 0.737 0.263
F41 Other anxiety disorders
0.262 0.738 0.000
F41.2 Mixed anxiety and depressive disorder
0.257 0.743 0.000
E78.0 Pure hypercholesterolaemia
0.257 0.743 0.000
E11.2 With renal complications
0.000 0.745 0.255
E07.8 Other specified disorders of thyroid
0.000 0.750 0.250
R04 Haemorrhage from respiratory passages
0.244 0.756 0.000
E29.8 Other testicular dysfunction
0.001 0.757 0.242
E29.0 Testicular hyperfunction
0.001 0.757 0.242
E66 Obesity
0.000 0.758 0.242
E23 Hypofunction and other disorders of pituitary gland
0.001 0.761 0.239
E28.3 Primary ovarian failure
0.000 0.761 0.239
E26.8 Other hyperaldosteronism
0.001 0.763 0.236
E26.1 Secondary hyperaldosteronism
0.001 0.763 0.236
E29.9 Testicular dysfunction, unspecified
0.001 0.773 0.226
E66.8 Other obesity
0.000 0.775 0.225
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.777 0.223
T40.5 Cocaine
0.220 0.780 0.000
E67.8 Other specified hyperalimentation
0.000 0.781 0.219
E67.3 Hypervitaminosis D
0.000 0.781 0.219
E67.2 Megavitamin-B6 syndrome
0.000 0.781 0.219
E67.1 Hypercarotenaemia
0.000 0.781 0.219
E67.0 Hypervitaminosis A
0.000 0.781 0.219
F40-F48 Neurotic, stress-related and somatoform disorders
0.219 0.781 0.000
N04.9 Unspecified
0.000 0.783 0.217
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.785 0.215
E11.3 With ophthalmic complications
0.000 0.790 0.210
N04 Nephrotic syndrome
0.000 0.791 0.209
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.794 0.206
E22.8 Other hyperfunction of pituitary gland
0.000 0.794 0.206
F43 Reaction to severe stress, and adjustment disorders
0.206 0.794 0.000
F43.0 Acute stress reaction
0.205 0.795 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.203 0.797 0.000
T40.8 Lysergide [LSD]
0.203 0.797 0.000
T40.7 Cannabis (derivatives)
0.203 0.797 0.000
T40.3 Methadone
0.203 0.797 0.000
T40.0 Opium
0.203 0.797 0.000
F40 Phobic anxiety disorders
0.202 0.798 0.000
E03 Other hypothyroidism
0.000 0.800 0.199
T40.1 Heroin
0.196 0.804 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.195 0.805 0.000
N00-N08 Glomerular diseases
0.000 0.806 0.193
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.807 0.193
F40.2 Specific (isolated) phobias
0.192 0.808 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.812 0.186
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.815 0.185
E23.2 Diabetes insipidus
0.000 0.816 0.183
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.817 0.183
R04.1 Haemorrhage from throat
0.182 0.818 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.820 0.179
E22.1 Hyperprolactinaemia
0.000 0.821 0.179
R04.9 Haemorrhage from respiratory passages, unspecified
0.175 0.825 0.000
I26 Pulmonary embolism
0.000 0.825 0.175
N04.1 Focal and segmental glomerular lesions
0.000 0.826 0.174
E66.1 Drug-induced obesity
0.000 0.826 0.174
F41.3 Other mixed anxiety disorders
0.173 0.827 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.828 0.171
E23.1 Drug-induced hypopituitarism
0.001 0.828 0.171
N04.2 Diffuse membranous glomerulonephritis
0.000 0.829 0.171
N05 Unspecified nephritic syndrome
0.000 0.830 0.170
F48 Other neurotic disorders
0.169 0.831 0.000
E04 Other non-toxic goitre
0.000 0.831 0.169
E21.2 Other hyperparathyroidism
0.000 0.835 0.165
L40-L45 Papulosquamous disorders
0.157 0.836 0.007
E14.9 Without complications
0.000 0.836 0.164
T40.2 Other opioids
0.162 0.838 0.000
F40.9 Phobic anxiety disorder, unspecified
0.162 0.838 0.000
N05.2 Diffuse membranous glomerulonephritis
0.000 0.840 0.160
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.841 0.159
E65 Localised adiposity
0.001 0.843 0.156
F40.1 Social phobias
0.157 0.843 0.000
F43.2 Adjustment disorders
0.156 0.844 0.000
T40.6 Other and unspecified narcotics
0.155 0.845 0.000
E23.6 Other disorders of pituitary gland
0.001 0.846 0.154
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.849 0.151
N04.8 Other
0.000 0.850 0.150
N04.7 Diffuse crescentic glomerulonephritis
0.000 0.850 0.150
N04.6 Dense deposit disease
0.000 0.850 0.150
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.850 0.150
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.850 0.150
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.850 0.150
F43.8 Other reactions to severe stress
0.148 0.852 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.147 0.853 0.000
F40.8 Other phobic anxiety disorders
0.146 0.854 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.855 0.145
E03.5 Myxoedema coma
0.000 0.857 0.143
E03.4 Atrophy of thyroid (acquired)
0.000 0.857 0.143
E03.3 Postinfectious hypothyroidism
0.000 0.857 0.143
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.857 0.143

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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