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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1055569
log Bayes Factor = 24.3332
Chromosome 6   position 31,440,082  (GRCh37) Explore rs1055569 on Ensembl!
Variant rs1055569 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.004 0.996
E10.1 With ketoacidosis
0.000 0.012 0.988
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.013 0.987
E10-E14 Diabetes mellitus
0.000 0.026 0.974
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.052 0.948
H36.0 Diabetic retinopathy
0.000 0.055 0.945
E00-E07 Disorders of thyroid gland
0.000 0.060 0.940
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.066 0.934
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.067 0.933
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.080 0.920
E10.2 With renal complications
0.000 0.090 0.910
E10.0 With coma
0.000 0.095 0.905
E16 Other disorders of pancreatic internal secretion
0.000 0.100 0.900
M06 Other rheumatoid arthritis
0.000 0.106 0.894
E10.4 With neurological complications
0.000 0.115 0.885
E16.2 Hypoglycaemia, unspecified
0.000 0.116 0.884
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.121 0.879
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.124 0.876
E04 Other non-toxic goitre
0.000 0.150 0.850
M06.0 Seronegative rheumatoid arthritis
0.000 0.150 0.850
E20-E35 Disorders of other endocrine glands
0.000 0.157 0.843
E27 Other disorders of adrenal gland
0.000 0.165 0.835
E27.1 Primary adrenocortical insufficiency
0.000 0.168 0.832
E11 Non-insulin-dependent diabetes mellitus
0.000 0.168 0.832
H36 Retinal disorders in diseases classified elsewhere
0.000 0.181 0.819
E04.9 Non-toxic goitre, unspecified
0.000 0.189 0.811
E11.3 With ophthalmic complications
0.000 0.191 0.809
E11.1 With ketoacidosis
0.000 0.199 0.801
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.208 0.792
E10.5 With peripheral circulatory complications
0.000 0.209 0.791
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.222 0.778
E10.6 With other specified complications
0.000 0.233 0.767
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.240 0.760
E07 Other disorders of thyroid
0.000 0.243 0.757
E10.8 With unspecified complications
0.000 0.251 0.749
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.253 0.747
E04.0 Non-toxic diffuse goitre
0.000 0.258 0.742
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.259 0.741
E22 Hyperfunction of pituitary gland
0.000 0.264 0.735
E14 Unspecified diabetes mellitus
0.000 0.270 0.730
H30-H36 Disorders of choroid and retina
0.000 0.271 0.729
E10.7 With multiple complications
0.000 0.283 0.717
E07.8 Other specified disorders of thyroid
0.000 0.285 0.715
M06.3 Rheumatoid nodule
0.000 0.285 0.715
M06.4 Inflammatory polyarthropathy
0.000 0.286 0.714
E12 Malnutrition-related diabetes mellitus
0.000 0.302 0.698
E40-E46 Malnutrition
0.000 0.309 0.691
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.315 0.685
E06 Thyroiditis
0.000 0.316 0.684
E11.8 With unspecified complications
0.000 0.317 0.683
E20 Hypoparathyroidism
0.000 0.324 0.676
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.326 0.674
E00 Congenital iodine-deficiency syndrome
0.000 0.326 0.674
E27.2 Addisonian crisis
0.000 0.326 0.674
E05.5 Thyroid crisis or storm
0.000 0.331 0.669
E05.4 Thyrotoxicosis factitia
0.000 0.331 0.669
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.331 0.669
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.331 0.669
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.332 0.668
H33 Retinal detachments and breaks
0.000 0.335 0.665
E14.3 With ophthalmic complications
0.000 0.338 0.662
E15 Nondiabetic hypoglycaemic coma
0.000 0.340 0.660
K90 Intestinal malabsorption
0.000 0.342 0.658
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.349 0.651
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.355 0.645
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.355 0.645
E16.4 Abnormal secretion of gastrin
0.000 0.355 0.645
E16.3 Increased secretion of glucagon
0.000 0.355 0.645
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.355 0.645
M06.2 Rheumatoid bursitis
0.000 0.359 0.641
M06.1 Adult-onset Still's disease
0.000 0.359 0.641
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.361 0.639
H34 Retinal vascular occlusions
0.000 0.363 0.637
E28 Ovarian dysfunction
0.000 0.366 0.634
H33.3 Retinal breaks without detachment
0.000 0.367 0.633
H35 Other retinal disorders
0.000 0.387 0.613
E04.8 Other specified non-toxic goitre
0.000 0.390 0.610
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.390 0.610
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.390 0.610
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.390 0.610
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.390 0.610
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.390 0.610
M06.8 Other specified rheumatoid arthritis
0.000 0.393 0.607
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.395 0.605
E32 Diseases of thymus
0.000 0.395 0.605
E31 Polyglandular dysfunction
0.000 0.395 0.605
E30 Disorders of puberty, not elsewhere classified
0.000 0.395 0.605
H35.8 Other specified retinal disorders
0.000 0.395 0.605
E22.0 Acromegaly and pituitary gigantism
0.000 0.398 0.602
E27.5 Adrenomedullary hyperfunction
0.000 0.401 0.599
E27.0 Other adrenocortical overactivity
0.000 0.401 0.599
E11.7 With multiple complications
0.000 0.404 0.596
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.405 0.595
E25 Adrenogenital disorders
0.000 0.407 0.593
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.409 0.591
E14.6 With other specified complications
0.000 0.409 0.591
H33.4 Traction detachment of retina
0.000 0.409 0.591
E11.5 With peripheral circulatory complications
0.000 0.411 0.589
H34.2 Other retinal artery occlusions
0.000 0.411 0.589
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.413 0.587
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.421 0.579
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.429 0.571
E06.3 Autoimmune thyroiditis
0.000 0.429 0.571
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.432 0.568
E22.1 Hyperprolactinaemia
0.000 0.443 0.557
E14.1 With ketoacidosis
0.000 0.444 0.556
E20.9 Hypoparathyroidism, unspecified
0.000 0.444 0.556
K91.4 Colostomy and enterostomy malfunction
0.000 0.445 0.555
H33.2 Serous retinal detachment
0.000 0.448 0.552
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.449 0.551
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.449 0.551
K90-K93 Other diseases of the digestive system
0.000 0.450 0.550
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.452 0.548
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.455 0.545
E27.8 Other specified disorders of adrenal gland
0.000 0.456 0.544
E07.1 Dyshormogenetic goitre
0.000 0.457 0.543
E07.0 Hypersecretion of calcitonin
0.000 0.457 0.543
H35.2 Other proliferative retinopathy
0.000 0.457 0.543
E16.1 Other hypoglycaemia
0.000 0.468 0.532
H30 Chorioretinal inflammation
0.000 0.469 0.531
E13 Other specified diabetes mellitus
0.000 0.471 0.528
E14.8 With unspecified complications
0.000 0.472 0.528
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.473 0.527
E22.8 Other hyperfunction of pituitary gland
0.000 0.473 0.527
E14.7 With multiple complications
0.000 0.477 0.523
E14.0 With coma
0.000 0.477 0.523
H33.1 Retinoschisis and retinal cysts
0.000 0.477 0.523
K90.8 Other intestinal malabsorption
0.000 0.477 0.523
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.477 0.523
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.480 0.520
H34.9 Retinal vascular occlusion, unspecified
0.000 0.481 0.519
M06.34 Rheumatoid nodule (Hand)
0.000 0.484 0.516
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.487 0.513
M06.38 Rheumatoid nodule (Other)
0.000 0.487 0.513
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.487 0.513
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.487 0.513
M06.33 Rheumatoid nodule (Forearm)
0.000 0.487 0.513
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.487 0.513
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.488 0.512
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.488 0.512
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.488 0.512
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.488 0.512
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.488 0.512
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.488 0.512
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.488 0.512
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.488 0.512
E26 Hyperaldosteronism
0.000 0.492 0.508
E46 Unspecified protein-energy malnutrition
0.000 0.493 0.507
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.498 0.502
E12.9 Without complications
0.000 0.499 0.500
E12.8 With unspecified complications
0.000 0.499 0.500
E12.7 With multiple complications
0.000 0.499 0.500
E12.6 With other specified complications
0.000 0.499 0.500
E12.5 With peripheral circulatory complications
0.000 0.499 0.500
E12.4 With neurological complications
0.000 0.499 0.500
E12.3 With ophthalmic complications
0.000 0.499 0.500
E12.2 With renal complications
0.000 0.499 0.500
E12.1 With ketoacidosis
0.000 0.499 0.500
E12.0 With coma
0.000 0.499 0.500
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.499 0.501
E24 Cushing's syndrome
0.000 0.499 0.500
E29 Testicular dysfunction
0.000 0.500 0.500
E14.2 Withrenal complications
0.000 0.502 0.498
R17 Unspecified jaundice
0.000 0.503 0.497
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.504 0.496
E45 Retarded development following protein-energy malnutrition
0.000 0.504 0.496
E43 Unspecified severe protein-energy malnutrition
0.000 0.504 0.496
E42 Marasmic kwashiorkor
0.000 0.504 0.496
E41 Nutritional marasmus
0.000 0.504 0.496
E40 Kwashiorkor
0.000 0.504 0.496
E06.5 Other chronic thyroiditis
0.000 0.507 0.493
E27.9 Disorder of adrenal gland, unspecified
0.000 0.509 0.491
E06.4 Drug-induced thyroiditis
0.000 0.509 0.491
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.509 0.491
E06.0 Acute thyroiditis
0.000 0.509 0.491
E04.2 Non-toxic multinodular goitre
0.000 0.511 0.488
E23 Hypofunction and other disorders of pituitary gland
0.000 0.512 0.488
E20.8 Other hypoparathyroidism
0.000 0.515 0.484
E20.1 Pseudohypoparathyroidism
0.000 0.515 0.484
E20.0 Idiopathic hypoparathyroidism
0.000 0.515 0.484
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.516 0.483
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.516 0.483
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.516 0.483
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.516 0.483
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.516 0.483
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.516 0.483
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.516 0.483
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.516 0.483
H31 Other disorders of choroid
0.000 0.527 0.473
K90.3 Pancreatic steatorrhoea
0.000 0.528 0.471
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.528 0.471
K90.1 Tropical sprue
0.000 0.528 0.471
E28.2 Polycystic ovarian syndrome
0.000 0.529 0.471
E28.3 Primary ovarian failure
0.000 0.530 0.470
E05.9 Thyrotoxicosis, unspecified
0.000 0.532 0.468
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.540 0.460
M06.18 Adult-onset Still's disease (Other)
0.000 0.540 0.460
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.540 0.460
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.540 0.460
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.540 0.460
M06.14 Adult-onset Still's disease (Hand)
0.000 0.540 0.460
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.540 0.460
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.540 0.460
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.540 0.460
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.540 0.460
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.540 0.460
M06.28 Rheumatoid bursitis (Other)
0.000 0.540 0.460
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.540 0.460
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.540 0.460
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.540 0.460
M06.24 Rheumatoid bursitis (Hand)
0.000 0.540 0.460
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.540 0.460
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.540 0.460
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.540 0.460
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.540 0.460
E11.6 With other specified complications
0.000 0.541 0.459
H35.0 Background retinopathy and retinal vascular changes
0.000 0.542 0.458
H34.0 Transient retinal artery occlusion
0.000 0.543 0.457
E28.9 Ovarian dysfunction, unspecified
0.000 0.545 0.455
E28.8 Other ovarian dysfunction
0.000 0.545 0.455
E28.1 Androgen excess
0.000 0.545 0.455
E28.0 Oestrogen excess
0.000 0.545 0.455
E06.9 Thyroiditis, unspecified
0.000 0.548 0.452
E11.2 With renal complications
0.000 0.550 0.450
E05.8 Other thyrotoxicosis
0.001 0.554 0.446
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.554 0.446
H34.8 Other retinal vascular occlusions
0.000 0.556 0.444
H35.1 Retinopathy of prematurity
0.000 0.560 0.440
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.437 0.563 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.565 0.435
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.565 0.435
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.565 0.435
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.565 0.435
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.565 0.435
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.565 0.435
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.565 0.435
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.565 0.435
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.565 0.435
E14.5 With peripheral circulatory complications
0.000 0.566 0.434
E30.9 Disorder of puberty, unspecified
0.000 0.566 0.433
E30.8 Other disorders of puberty
0.000 0.566 0.433
E30.1 Precocious puberty
0.000 0.566 0.433
E30.0 Delayed puberty
0.000 0.566 0.433
E31.9 Polyglandular dysfunction, unspecified
0.000 0.566 0.433
E31.8 Other polyglandular dysfunction
0.000 0.566 0.433
E31.1 Polyglandular hyperfunction
0.000 0.566 0.433
E31.0 Autoimmune polyglandular failure
0.000 0.566 0.433
E32.9 Disease of thymus, unspecified
0.000 0.566 0.433
E32.8 Other diseases of thymus
0.000 0.566 0.433
E32.1 Abscess of thymus
0.000 0.566 0.433
E32.0 Persistent hyperplasia of thymus
0.000 0.566 0.433
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.566 0.433
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.566 0.433
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.566 0.433
E50-E64 Other nutritional deficiencies
0.000 0.572 0.428
E25.9 Adrenogenital disorder, unspecified
0.000 0.575 0.425
E25.8 Other adrenogenital disorders
0.000 0.575 0.425
H35.5 Hereditary retinal dystrophy
0.000 0.578 0.422
E06.1 Subacute thyroiditis
0.000 0.581 0.419
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.583 0.416
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.585 0.415
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.587 0.413
E14.4 With neurological complications
0.000 0.589 0.411
E11.0 With coma
0.000 0.591 0.409
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.599 0.401
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.606 0.394
E23.6 Other disorders of pituitary gland
0.000 0.610 0.390
H30.9 Chorioretinal inflammation, unspecified
0.000 0.611 0.389
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.616 0.384
H30.8 Other chorioretinal inflammations
0.000 0.619 0.380
H30.2 Posterior cyclitis
0.000 0.619 0.380
H30.1 Disseminated chorioretinal inflammation
0.000 0.619 0.380
H30.0 Focal chorioretinal inflammation
0.000 0.619 0.380
E13.8 With unspecified complications
0.000 0.621 0.379
E13.7 With multiple complications
0.000 0.621 0.379
E13.6 With other specified complications
0.000 0.621 0.379
E13.5 With peripheral circulatory complications
0.000 0.621 0.379
E13.4 With neurological complications
0.000 0.621 0.379
E13.3 With ophthalmic complications
0.000 0.621 0.379
E13.2 With renal complications
0.000 0.621 0.379
E13.1 With ketoacidosis
0.000 0.621 0.379
E13.0 With coma
0.000 0.621 0.379
H35.6 Retinal haemorrhage
0.000 0.622 0.378
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.000 0.625 0.375
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.000 0.625 0.375
E24.2 Drug-induced Cushing's syndrome
0.000 0.631 0.369
E26.8 Other hyperaldosteronism
0.000 0.636 0.364
E26.1 Secondary hyperaldosteronism
0.000 0.636 0.364
K91.5 Postcholecystectomy syndrome
0.000 0.639 0.361
E24.8 Other Cushing's syndrome
0.000 0.641 0.359
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.641 0.359
E24.3 Ectopic ACTH syndrome
0.000 0.641 0.359
E24.1 Nelson's syndrome
0.000 0.641 0.359
E29.8 Other testicular dysfunction
0.000 0.641 0.359
E29.0 Testicular hyperfunction
0.000 0.641 0.359
H35.7 Separation of retinal layers
0.000 0.641 0.359
E44.1 Mild protein-energy malnutrition
0.000 0.644 0.355
E44.0 Moderate protein-energy malnutrition
0.000 0.644 0.355
E24.0 Pituitary-dependent Cushing's disease
0.000 0.646 0.353
K91.1 Postgastric surgery syndromes
0.000 0.647 0.353
H31.3 Choroidal haemorrhage and rupture
0.000 0.649 0.351
E34 Other endocrine disorders
0.000 0.650 0.350
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.650 0.350
E23.1 Drug-induced hypopituitarism
0.000 0.650 0.350
H31.8 Other specified disorders of choroid
0.000 0.654 0.346
E14.9 Without complications
0.000 0.656 0.344
H31.1 Choroidal degeneration
0.000 0.657 0.343
E23.2 Diabetes insipidus
0.000 0.659 0.340
H31.4 Choroidal detachment
0.000 0.661 0.339
H31.2 Hereditary choroidal dystrophy
0.000 0.661 0.339
E29.9 Testicular dysfunction, unspecified
0.000 0.664 0.335
H31.9 Disorder of choroid, unspecified
0.000 0.667 0.332
E26.9 Hyperaldosteronism, unspecified
0.000 0.671 0.329
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.328 0.672 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.684 0.315
E26.0 Primary hyperaldosteronism
0.000 0.685 0.315
E58 Dietary calcium deficiency
0.000 0.689 0.310
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.693 0.307
E63 Other nutritional deficiencies
0.000 0.693 0.307
E51 Thiamine deficiency
0.000 0.693 0.307
E50 Vitamin A deficiency
0.000 0.693 0.307
E60 Dietary zinc deficiency
0.000 0.693 0.307
E59 Dietary selenium deficiency
0.000 0.693 0.307
E54 Ascorbic acid deficiency
0.000 0.693 0.307
E52 Niacin deficiency [pellagra]
0.000 0.693 0.307
K91.3 Postoperative intestinal obstruction
0.000 0.695 0.305
E65-E68 Obesity and other hyperalimentation
0.000 0.695 0.304
E55 Vitamin D deficiency
0.000 0.695 0.304
E56 Other vitamin deficiencies
0.000 0.700 0.300
E29.1 Testicular hypofunction
0.000 0.711 0.289
H34.1 Central retinal artery occlusion
0.001 0.712 0.287
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.717 0.283
K93.1 Megacolon in Chagas' disease
0.000 0.717 0.283
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.717 0.283
C82.3 Follicular lymphoma grade IIIa
0.283 0.717 0.000
H35.9 Retinal disorder, unspecified
0.000 0.718 0.282
E03 Other hypothyroidism
0.000 0.728 0.272
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.271 0.729 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.731 0.269
C82.1 Mixed small cleaved and large cell, follicular
0.268 0.732 0.000
H31.0 Chorioretinal scars
0.000 0.734 0.266
H35.4 Peripheral retinal degeneration
0.000 0.736 0.264
C82.0 Small cleaved cell, follicular
0.256 0.744 0.000
E34.5 Androgen resistance syndrome
0.000 0.749 0.251
E34.4 Constitutional tall stature
0.000 0.749 0.251
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.749 0.251
E34.1 Other hypersecretion of intestinal hormones
0.000 0.749 0.251
E24.9 Cushing's syndrome, unspecified
0.000 0.754 0.246
E34.0 Carcinoid syndrome
0.000 0.761 0.238
C82.6 Cutaneous follicle centre lymphoma
0.235 0.765 0.000
C82.5 Diffuse follicle centre lymphoma
0.235 0.765 0.000
C82.4 Follicular lymphoma grade IIIb
0.234 0.766 0.000
E34.3 Short stature, not elsewhere classified
0.001 0.770 0.230
E53 Deficiency of other B group vitamins
0.000 0.774 0.226
E50.9 Vitamin A deficiency, unspecified
0.000 0.780 0.220
E50.8 Other manifestations of vitamin A deficiency
0.000 0.780 0.220
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.780 0.220
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.780 0.220
E50.5 Vitamin A deficiency with night blindness
0.000 0.780 0.220
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.780 0.220
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.780 0.220
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.780 0.220
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.780 0.220
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.780 0.220
E51.9 Thiamine deficiency, unspecified
0.000 0.780 0.220
E51.8 Other manifestations of thiamine deficiency
0.000 0.780 0.220
E51.2 Wernicke's encephalopathy
0.000 0.780 0.220
E51.1 Beriberi
0.000 0.780 0.220
E63.9 Nutritional deficiency, unspecified
0.000 0.780 0.220
E63.8 Other specified nutritional deficiencies
0.000 0.780 0.220
E63.1 Imbalance of constituents of food intake
0.000 0.780 0.220
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.780 0.220
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.780 0.220
E64.8 Sequelae of other nutritional deficiencies
0.000 0.780 0.220
E64.3 Sequelae of rickets
0.000 0.780 0.220
E64.2 Sequelae of vitamin C deficiency
0.000 0.780 0.220
E64.1 Sequelae of vitamin A deficiency
0.000 0.780 0.220
E64.0 Sequelae of protein-energy malnutrition
0.000 0.780 0.220
E23.0 Hypopituitarism
0.000 0.780 0.219
E67 Other hyperalimentation
0.000 0.781 0.218
E68 Sequelae of hyperalimentation
0.000 0.781 0.218
E55.0 Rickets, active
0.000 0.781 0.218
E55.9 Vitamin D deficiency, unspecified
0.000 0.784 0.216
E56.9 Vitamin deficiency, unspecified
0.000 0.785 0.215
E56.8 Deficiency of other vitamins
0.000 0.785 0.215
E56.0 Deficiency of vitamin E
0.000 0.785 0.215
E61 Deficiency of other nutrient elements
0.000 0.787 0.213
E13.9 Without complications
0.001 0.790 0.209
E56.1 Deficiency of vitamin K
0.000 0.792 0.208
E34.8 Other specified endocrine disorders
0.001 0.792 0.207
K90.9 Intestinal malabsorption, unspecified
0.000 0.793 0.206
E03.5 Myxoedema coma
0.000 0.805 0.195
E03.4 Atrophy of thyroid (acquired)
0.000 0.805 0.195
E03.3 Postinfectious hypothyroidism
0.000 0.805 0.195
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.805 0.195
E03.8 Other specified hypothyroidism
0.000 0.812 0.188
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.816 0.184
C82.2 Large cell, follicular
0.181 0.818 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.828 0.171
E03.1 Congenital hypothyroidism without goitre
0.000 0.836 0.164
E53.1 Pyridoxine deficiency
0.000 0.838 0.162
E53.0 Riboflavin deficiency
0.000 0.838 0.162
E67.8 Other specified hyperalimentation
0.000 0.843 0.157
E67.3 Hypervitaminosis D
0.000 0.843 0.157
E67.2 Megavitamin-B6 syndrome
0.000 0.843 0.157
E67.1 Hypercarotenaemia
0.000 0.843 0.157
E67.0 Hypervitaminosis A
0.000 0.843 0.157
E61.2 Magnesium deficiency
0.000 0.845 0.154
E61.9 Deficiency of nutrient element, unspecified
0.000 0.847 0.153
E61.8 Deficiency of other specified nutrient elements
0.000 0.847 0.153
E61.7 Deficiency of multiple nutrient elements
0.000 0.847 0.153
E61.6 Vanadium deficiency
0.000 0.847 0.153
E61.5 Molybdenum deficiency
0.000 0.847 0.153
E61.4 Chromium deficiency
0.000 0.847 0.153
E61.3 Manganese deficiency
0.000 0.847 0.153
E61.0 Copper deficiency
0.000 0.847 0.153
E65 Localised adiposity
0.000 0.849 0.150
E53.9 Vitamin B deficiency, unspecified
0.000 0.850 0.150
H33.0 Retinal detachment with retinal break
0.000 0.851 0.149
M05-M14 Inflammatory polyarthropathies
0.000 0.864 0.136
H35.3 Degeneration of macula and posterior pole
0.000 0.865 0.135
H33.5 Other retinal detachments
0.002 0.875 0.122
M10 Gout
0.000 0.891 0.108
E53.8 Deficiency of other specified B group vitamins
0.000 0.895 0.105
R31 Unspecified haematuria
0.101 0.899 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.002 0.900 0.098
M14 Arthropathies in other diseases classified elsewhere
0.000 0.900 0.100
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.902 0.098
M08 Juvenile arthritis
0.000 0.902 0.098
M12 Other specific arthropathies
0.000 0.904 0.095
E11.4 With neurological complications
0.001 0.907 0.093
M07 Psoriatic and enteropathic arthropathies
0.000 0.911 0.089
M10.0 Idiopathic gout
0.000 0.913 0.087
E07.9 Disorder of thyroid, unspecified
0.002 0.917 0.080
M13 Other arthritis
0.000 0.920 0.080
M10.9 Gout, unspecified
0.000 0.920 0.080
M10.4 Other secondary gout
0.000 0.922 0.078
M10.3 Gout due to impairment of renal function
0.000 0.922 0.078
M10.2 Drug-induced gout
0.000 0.922 0.078
M10.1 Lead-induced gout
0.000 0.922 0.078
M11 Other crystal arthropathies
0.000 0.924 0.075
M10.07 Idiopathic gout (Ankle and foot)
0.000 0.925 0.075
M14.6 Neuropathic arthropathy
0.000 0.926 0.073
E21.4 Other specified disorders of parathyroid gland
0.002 0.928 0.071
E21.5 Disorder of parathyroid gland, unspecified
0.002 0.928 0.071
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.928 0.072
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.928 0.072
M14.4 Arthropathy in amyloidosis
0.000 0.928 0.072
M14.3 Lipoid dermatoarthritis
0.000 0.928 0.072
M14.2 Diabetic arthropathy
0.000 0.928 0.072
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.928 0.072
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.928 0.072
E21.2 Other hyperparathyroidism
0.002 0.929 0.070
M08.9 Juvenile arthritis, unspecified
0.000 0.930 0.070
M08.8 Other juvenile arthritis
0.000 0.930 0.070
M08.4 Pauciarticular juvenile arthritis
0.000 0.930 0.070
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.930 0.070
M08.2 Juvenile arthritis with systemic onset
0.000 0.930 0.070
M08.1 Juvenile ankylosing spondylitis
0.000 0.930 0.070
M08.0 Juvenile rheumatoid arthritis
0.000 0.930 0.070
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.930 0.070
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.930 0.070
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.930 0.070
M09.0 Juvenile arthritis in psoriasis
0.000 0.930 0.070
M12.3 Palindromic rheumatism
0.000 0.930 0.070
M10.93 Gout, unspecified (Forearm)
0.000 0.930 0.070
K92 Other diseases of digestive system
0.000 0.931 0.069
M10.90 Gout, unspecified (Multiple sites)
0.000 0.931 0.069
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.931 0.068
M12.5 Traumatic arthropathy
0.000 0.931 0.068
M12.4 Intermittent hydrarthrosis
0.000 0.931 0.068
M12.1 Kaschin-Beck disease
0.000 0.931 0.068
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.931 0.068
M13.0 Polyarthritis, unspecified
0.000 0.933 0.066
M12.2 Villonodular synovitis (pigmented)
0.000 0.935 0.064
M07.6 Other enteropathic arthropathies
0.000 0.936 0.064
M07.5 Arthropathy in ulcerative colitis
0.000 0.936 0.064
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.936 0.064
M07.2 Psoriatic spondylitis
0.000 0.936 0.064
M07.1 Arthritis mutilans
0.000 0.936 0.064
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.936 0.064
M10.94 Gout, unspecified (Hand)
0.000 0.936 0.064
M13.1 Monoarthritis, not elsewhere classified
0.000 0.937 0.063
M10.08 Idiopathic gout (Other)
0.000 0.937 0.063
M10.06 Idiopathic gout (Lower leg)
0.000 0.937 0.063
M10.05 Idiopathic gout (Pelvic region and thigh)
0.000 0.937 0.063
M10.04 Idiopathic gout (Hand)
0.000 0.937 0.063
M10.03 Idiopathic gout (Forearm)
0.000 0.937 0.063
M10.02 Idiopathic gout (Upper arm)
0.000 0.937 0.063
M10.01 Idiopathic gout (Shoulder region)
0.000 0.937 0.063
M10.00 Idiopathic gout (Multiple sites)
0.000 0.937 0.063
M05 Seropositive rheumatoid arthritis
0.000 0.939 0.061
M10.98 Gout, unspecified (Other)
0.000 0.942 0.057
M10.95 Gout, unspecified (Pelvic region and thigh)
0.000 0.942 0.057

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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